facial nerve

Summary

Summary: The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and salivary glands, and convey afferent information for taste from the anterior two-thirds of the tongue and for touch from the external ear.

Top Publications

  1. ncbi Re-activation of atrophic motor Schwann cells after hypoglossal-facial nerve anastomosis
    Maria Adele Rueger
    Institut I fur Anatomie, der Universität zu Köln, D 50924 Koln, Germany
    Neurosci Lett 434:253-9. 2008
  2. ncbi Expression patterns in alternative splicing forms of prosaposin mRNA in the rat facial nerve nucleus after facial nerve transection
    Jie Chen
    Division of Anatomy and Embryology, Department of Integrated Basic Medical Science, Ehime University School of Medicine, Shitsukawa, To on, Ehime 791 0295, Japan
    Neurosci Res 60:82-94. 2008
  3. ncbi Monitoring of facial evoked EMG for hemifacial spasm: a critical analysis of its prognostic value
    N Kiya
    Department of Neurosurgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan
    Acta Neurochir (Wien) 143:365-8. 2001
  4. ncbi Hemihypoglossal-facial neurorrhaphy after mastoid dissection of the facial nerve: results in 24 patients and comparison with the classic technique
    Roberto S Martins
    Department of Neurosurgery, Peripheral Nerve Surgery Unit, University of Sao Paulo Medical School, and Hospital Santa Marcelina, Sao Paulo, Brazil
    Neurosurgery 63:310-6; discussion 317. 2008
  5. ncbi Combined use of decellularized allogeneic artery conduits with autologous transdifferentiated adipose-derived stem cells for facial nerve regeneration in rats
    Fei Sun
    Department of Otolaryngology Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, China
    Biomaterials 32:8118-28. 2011
  6. pmc Improved facial nerve identification with novel fluorescently labeled probe
    Amy P Wu
    Division of Otolaryngology Head and Neck Surgery, University of California San Diego, San Diego, California 92093 0647, USA
    Laryngoscope 121:805-10. 2011
  7. ncbi Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve
    Eileen M Foecking
    Department of Otolaryngology Head and Neck Surgery, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA
    J Rehabil Res Dev 49:451-8. 2012
  8. ncbi Outcomes following parotidectomy for metastatic squamous cell carcinoma with microscopic residual disease: implications for facial nerve preservation
    N Gopalakrishna Iyer
    Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, Australia
    Head Neck 31:21-7. 2009
  9. pmc Optical stimulation of the facial nerve: a new monitoring technique?
    Ingo Ulrik Teudt
    Department of Otolaryngology Head and Neck Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611 3008, USA
    Laryngoscope 117:1641-7. 2007
  10. ncbi Impairment of microglial responses to facial nerve axotomy in cathepsin S-deficient mice
    Hai Peng Hao
    Laboratory of Oral Aging Science, Faculty of Dental Sciences, Kyushu University, Fukuoka, Japan
    J Neurosci Res 85:2196-206. 2007

Detail Information

Publications299 found, 100 shown here

  1. ncbi Re-activation of atrophic motor Schwann cells after hypoglossal-facial nerve anastomosis
    Maria Adele Rueger
    Institut I fur Anatomie, der Universität zu Köln, D 50924 Koln, Germany
    Neurosci Lett 434:253-9. 2008
    b>Facial nerve lesions are common in humans and often require surgical intervention...
  2. ncbi Expression patterns in alternative splicing forms of prosaposin mRNA in the rat facial nerve nucleus after facial nerve transection
    Jie Chen
    Division of Anatomy and Embryology, Department of Integrated Basic Medical Science, Ehime University School of Medicine, Shitsukawa, To on, Ehime 791 0295, Japan
    Neurosci Res 60:82-94. 2008
    ..We examined the expression patterns of the alternative splicing forms of prosaposin mRNA in the rat facial nerve nucleus for 52 days following facial nerve transection...
  3. ncbi Monitoring of facial evoked EMG for hemifacial spasm: a critical analysis of its prognostic value
    N Kiya
    Department of Neurosurgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan
    Acta Neurochir (Wien) 143:365-8. 2001
    ..However the outcome at 3 months suggested that waiting for some time before re-exploration is a better option, especially if the HFS had become mild...
  4. ncbi Hemihypoglossal-facial neurorrhaphy after mastoid dissection of the facial nerve: results in 24 patients and comparison with the classic technique
    Roberto S Martins
    Department of Neurosurgery, Peripheral Nerve Surgery Unit, University of Sao Paulo Medical School, and Hospital Santa Marcelina, Sao Paulo, Brazil
    Neurosurgery 63:310-6; discussion 317. 2008
    ..has been widely used for reanimation of paralyzed facial muscles after irreversible proximal injury of the facial nerve. However, complete section of the hypoglossal nerve occasionally results in hemiglossal dysfunction and ..
  5. ncbi Combined use of decellularized allogeneic artery conduits with autologous transdifferentiated adipose-derived stem cells for facial nerve regeneration in rats
    Fei Sun
    Department of Otolaryngology Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, China
    Biomaterials 32:8118-28. 2011
    ..artery conduit containing autologous transdifferentiated adipose-derived stem cells (dADSCs) on an 8-mm facial nerve branch lesion in a rat model...
  6. pmc Improved facial nerve identification with novel fluorescently labeled probe
    Amy P Wu
    Division of Otolaryngology Head and Neck Surgery, University of California San Diego, San Diego, California 92093 0647, USA
    Laryngoscope 121:805-10. 2011
    ..We evaluated the pattern of facial nerve labeling with fluorescently-labeled NP41 (F-NP41)...
  7. ncbi Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve
    Eileen M Foecking
    Department of Otolaryngology Head and Neck Surgery, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA
    J Rehabil Res Dev 49:451-8. 2012
    ..ways to enhance the regeneration of peripheral nerves using daily electrical stimulation (ES) following a facial nerve crush injury. In our previous studies, ES was not initiated until 24 h after injury...
  8. ncbi Outcomes following parotidectomy for metastatic squamous cell carcinoma with microscopic residual disease: implications for facial nerve preservation
    N Gopalakrishna Iyer
    Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, Australia
    Head Neck 31:21-7. 2009
    ..This study aims to determine whether facial nerve preservation followed by radiotherapy is a reasonable option in patients with microscopic residual disease ..
  9. pmc Optical stimulation of the facial nerve: a new monitoring technique?
    Ingo Ulrik Teudt
    Department of Otolaryngology Head and Neck Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611 3008, USA
    Laryngoscope 117:1641-7. 2007
    ..In contrast to electrical stimulation, pulsed infrared optical radiation can be used to safely and selectively stimulate neural tissue and might be valuable for screening...
  10. ncbi Impairment of microglial responses to facial nerve axotomy in cathepsin S-deficient mice
    Hai Peng Hao
    Laboratory of Oral Aging Science, Faculty of Dental Sciences, Kyushu University, Fukuoka, Japan
    J Neurosci Res 85:2196-206. 2007
    ..To better understand the role of CS in microglia, we investigated microglial responses after a facial nerve axotomy in CS-deficient (CS-/-) and wild-type mice...
  11. ncbi Surgical results of the Hypoglossal-Facial nerve Jump Graft technique
    L P Flores
    Unit of Neurosurgery, Hospital de Base do Distrito Federal Brasília, Distrito Federal, Brazil
    Acta Neurochir (Wien) 149:1205-10; discussion 1210. 2007
    The Hypoglossal-Facial nerve crossover has appeared as a surgical option for those scenarios where the facial nerve is injured in its intracranial course, but the conventional technique unequivocally leads to twelfth cranial nerve deficit...
  12. ncbi Hemifacial spasm: intraoperative electromyographic monitoring as a guide for microvascular decompression
    J J Mooij
    Department of Neurosurgery, University Hospital AZG, Groningen University, Groningen, The Netherlands
    Neurosurgery 49:1365-70; discussion 1370-1. 2001
    ..The aim of this study was to analyze whether intraoperative monitoring by stimulated electromyography of the facial nerve may help to improve the results of vascular decompression for HFS.
  13. ncbi Peripheral facial nerve axotomy in mice causes sprouting of motor axons into perineuronal central white matter: time course and molecular characterization
    Milan Makwana
    Department of Obstetrics and Gynaecology, EGA Institute for Women s Health, University College London, United Kingdom
    J Comp Neurol 518:699-721. 2010
    ..the appearance, composition and effects of gene deletions on intrabrainstem sprouts following peripheral facial nerve axotomy...
  14. ncbi Comparative evaluation of cytokine profiles and reactive gliosis supports a critical role for interleukin-6 in neuron-glia signaling during regeneration
    W J Streit
    Department of Neuroscience, University of Florida College of Medicine and Brain Institute, Gainesville 32611, Florida, USA
    J Neurosci Res 61:10-20. 2000
    ..reactive glial changes with astroglial and microglial markers reveals that the reactive gliosis following adult facial nerve axotomy is more intense than that observed in either of the other two paradigms...
  15. ncbi Focal application of neutralizing antibodies to soluble neurotrophic factors reduces collateral axonal branching after peripheral nerve lesion
    M Streppel
    Anatomical Institute, University of Cologne, 50931 Cologne, FR Germany
    Eur J Neurosci 15:1327-42. 2002
    ..analysis of local protein expression by immunocytochemistry and by in situ hybridization, we transected the facial nerve trunk of adult rats and inserted both ends into a silicon tube containing (i) collagen gel with neutralizing ..
  16. ncbi The effectiveness of neuromuscular facial retraining combined with electromyography in facial paralysis rehabilitation
    Gaye W Cronin
    Department of The Atlanta Ear Clinic, Atlanta, GA, USA
    Otolaryngol Head Neck Surg 128:534-8. 2003
    ..The study goal was to present the effectiveness of neuromuscular facial retraining techniques used in combination with electromyography for improving facial function even in cases of longstanding paralysis...
  17. ncbi The "babysitter" procedure: minihypoglossal to facial nerve transfer and cross-facial nerve grafting
    Julia K Terzis
    Department of Surgery, Division of Plastic and Reconstructive Surgery, and Microsurgical Program, Microsurgical Research Center, Eastern Virginia Medical School, Norfolk, VA 23501, USA
    Plast Reconstr Surg 123:865-76. 2009
    ..It involves two stages, with coaptation of ipsilateral 40 percent hypoglossal to facial nerve on the affected side, performed concomitantly with cross-facial nerve grafting and secondary microcoaptations 8 ..
  18. ncbi Predicting the long-term outcome after idiopathic facial nerve paralysis
    Konstantinos Mantsopoulos
    Department of Otorhinolaryngology Head and Neck Surgery, University of Erlangen Nuremberg, Erlangen, Germany
    Otol Neurotol 32:848-51. 2011
    ..To investigate long-term recovery after Bell's palsy and evaluate specific parameters for predicting the long-term outcome of facial weakness...
  19. ncbi Surgical management of glomus jugulare tumors: a proposal for approach selection based on tumor relationships with the facial nerve
    Luis A B Borba
    Department of Neurosurgery, Evangelic Medical School, Federal University of Parana, Curitiba, Parana, Brazil
    J Neurosurg 112:88-98. 2010
    ..jugulare tumor with the temporal bone and the results of its surgical treatment aiming at preservation of the facial nerve. Based on the tumor extension and its relationships with the facial nerve, new criteria to be used in the ..
  20. ncbi Transplantation of neural stem cells overexpressing glia-derived neurotrophic factor promotes facial nerve regeneration
    Yong Shi
    Department of Otolaryngology Head and Neck Surgery, Fudan University Affiliated Eye, Ear, Nose and Throat Hospital, Shanghai, China
    Acta Otolaryngol 129:906-14. 2009
    ..We constructed a biodegradable nerve conduit (NC) filled with NSCs overexpressing glia-derived neurotrophic factor (GDNF), which is known to protect facial motoneurons, and tested the effect of this NC on facial nerve regeneration.
  21. ncbi Displacement of the facial nerve course by vestibular schwannoma: preoperative visualization using diffusion tensor tractography
    Toshiaki Taoka
    Department of Radiology, Nara Medical University, Nara, and Higashiosaka City General Hospital, Osaka, Japan
    J Magn Reson Imaging 24:1005-10. 2006
    To preoperatively visualize the course of the facial nerve, which is displaced by vestibular schwannoma, using diffusion tensor (DT) tractography, and to evaluate the agreement with surgical findings.
  22. ncbi Diagnostic relevance of transcranial magnetic and electric stimulation of the facial nerve in the management of facial palsy
    Dennis A Nowak
    Department of Psychiatry III, University of Ulm, Germany
    Clin Neurophysiol 116:2051-7. 2005
    Earlier investigations have suggested that isolated conduction block of the facial nerve to transcranial magnetic stimulation early in the disorder represents a very sensitive and potentially specific finding in Bell's palsy ..
  23. ncbi Facial nerve dysfunction after parotidectomy: the role of local factors
    Christophe Gaillard
    Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine Saint Antoine, University of Paris VI Pierre et Marie Curie, Tenon Hospital, 75020 Paris, France
    Laryngoscope 115:287-91. 2005
    The objective was to analyze the incidence and factors associated with facial nerve dysfunction after conservative parotidectomy with facial nerve dissection.
  24. ncbi Nerve of origin, tumor size, hearing preservation, and facial nerve outcomes in 359 vestibular schwannoma resections at a tertiary care academic center
    Abraham Jacob
    Department of Otolaryngology Head and Neck Surgery, Ohio State University School of Medicine, Columbus, OH 43210, USA
    Laryngoscope 117:2087-92. 2007
    To determine nerve of origin, tumor size, hearing preservation rates, and facial nerve outcomes in a retrospective cohort study of patients undergoing translabyrinthine (TL), middle cranial fossa (MCF), and retrosigmoid/suboccipital (SO) ..
  25. ncbi Anatomic bases of superficial temporal artery and temporal branch of facial nerve
    Volkan Tayfur
    Department of Plastic Reconstructive and Aesthetic Surgery, Ondokuz Mayis University, Samsun, Turkey
    J Craniofac Surg 21:1945-7. 2010
    ..These operations may cause facial nerve injury...
  26. ncbi Preoperative detection of the facial nerve by high-field magnetic resonance imaging in patients with vestibular schwannoma
    Tomoaki Nakai
    Department of Neurosurgery, Kobe University Graduate School of Medicine, 7 5 2, Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
    Neuroradiology 55:615-20. 2013
    Preoperative knowledge of the position of the facial nerve relative to a vestibular schwannoma would be very helpful to decide for an adapted therapeutic strategy...
  27. ncbi Preservation of facial nerve function after postoperative vasoactive treatment in vestibular schwannoma surgery
    Christian Strauss
    Department of Neurosurgery, University of Halle Wittenberg, Halle, Germany
    Neurosurgery 59:577-84; discussion 577-84. 2006
    b>Facial nerve paresis and hearing loss are common complications after vestibular schwannoma surgery...
  28. ncbi Nimodipine promotes regeneration of peripheral facial nerve function after traumatic injury following maxillofacial surgery: an off label pilot-study
    K Scheller
    Department of Oral and Maxillofacial Surgery and Facial Plastic Surgery, Martin Luther University of Halle Wittenberg, Ernst Grube Strasse 40, 06120 Halle S, Germany
    J Craniomaxillofac Surg 40:427-34. 2012
    ..Encouraged by these positive results a pilot-study of nimodipine treatment in patients with a peripheral facial nerve (FN) paresis following maxillofacial surgery was performed...
  29. ncbi The course of the frontal branch of the facial nerve in relation to fascial planes: an anatomic study
    Cori A Agarwal
    Division of Plastic Surgery, University of UtahHealth Sciences Center, Salt Lake City, Utah 84132, USA
    Plast Reconstr Surg 125:532-7. 2010
    ..the anatomy of the temporal region, controversy still exists over the depth of the frontal branch of the facial nerve as it travels over the zygomatic arch...
  30. ncbi Unscheduled DNA synthesis and mitochondrial DNA synthetic rate following injury of the facial nerve
    H Korr
    Institute of Anatomy, RWTH Aachen, Germany
    Acta Neuropathol 94:557-66. 1997
    ..rates were determined autoradiographically in different cell types of the rodent brain 14 days after unilateral facial nerve transection...
  31. ncbi The frontal branch of the facial nerve across the zygomatic arch: anatomical relevance of the high-SMAS technique
    Andrew P Trussler
    Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Plast Reconstr Surg 125:1221-9. 2010
    ..This anatomical study defines the depth and fascial boundaries of the frontal branch of the facial nerve over the zygomatic arch.
  32. ncbi Imaging of the facial nerve
    F Veillona
    Service de Radiologie I, Hopital de Hautepierre, 67098 Strasbourg Cedex, France
    Eur J Radiol 74:341-8. 2010
    The facial nerve is responsible for the motor innervation of the face...
  33. ncbi Evaluation of electronspun silk fibroin-based transplants used for facial nerve repair
    Aijun Hu
    Department of Otolaryngology, the Second Affiliated Hospital of Soochow University, Soochow University, Suzhou, Jiangsu, People s Republic of China
    Otol Neurotol 34:311-8. 2013
    To study whether regenerated electrospun silk fibroin (SF) nanofibers as nerve conduits could improve nerve regeneration microenvironment and induce the facial nerve regeneration of Sprague-Dawley rats.
  34. ncbi A new model for facial nerve research: the novel transgenic Thy1-GFP rat
    Christina K Magill
    Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Facial Plast Surg 12:315-20. 2010
    ..transgenic rat model, whose axons constitutively express green fluorescent protein (GFP), in order to study facial nerve regeneration. Facial nerve injury can cause devastating physical and social sequelae...
  35. ncbi Electrophysiologic facial nerve monitoring during parotidectomy
    David W Eisele
    Division of Head and Neck and Endocrine Surgery, Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, San Francisco, California, USA
    Head Neck 32:399-405. 2010
    b>Facial nerve monitoring is an adjunctive method available to a surgeon during parotid surgery to assist with the functional preservation of the facial nerve...
  36. ncbi Electrodiagnostic studies of the facial nerve in peripheral facial palsy and hemifacial spasm
    Josep Valls-Sole
    Unitat d EMG, Servei de Neurologia, Hospital Clinic, Villarroel 170, Barcelona 08036, Spain
    Muscle Nerve 36:14-20. 2007
    ..EDX) assessment is one of the most important aspects in the evaluation of the two most common disorders of the facial nerve: facial palsy and hemifacial spasm...
  37. ncbi Branching patterns of the facial nerve and its communication with the auriculotemporal nerve
    H H Kwak
    Department of Oral Biology, Division of Anatomy and Developmental Biology, College of Dentistry, Oral Science Research Center, Brain Korea 21 Project for Medical Sciences, Yonsei University, 134 Shinchon dong, Seodaemoon gu Seoul, 120 752 Korea
    Surg Radiol Anat 26:494-500. 2004
    This study examines the anatomic relationships and variability of the facial nerve trunk and its branches, with emphasis on the intraparotid connections between the divisions...
  38. ncbi Recovery of facial nerve function after repair or grafting: our experience with 24 patients
    Deborah A Eaton
    Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Am J Otolaryngol 28:37-41. 2007
    The aim of this study was to review the outcomes of facial nerve repair and attempt to identify predictors of recovery time.
  39. ncbi Facial nerve repair with Gore-Tex tube and adipose-derived stem cells: an animal study in dogs
    Mehdi Ghoreishian
    Department of Oral and Maxillofacial Surgery and Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
    J Oral Maxillofac Surg 71:577-87. 2013
    ..The authors evaluated the capability of adipose-derived stem cells in Gore-Tex tubes to enhance facial nerve repair.
  40. ncbi Effects of hyperbaric oxygen therapy on facial nerve regeneration
    Daniela Salgado Alves Vilela
    Otorhinolaryngology Department, Santa Casa São Paulo, Faculty of Medical Sciences, Sao Paulo, Brazil
    Acta Otolaryngol 128:1048-52. 2008
    ..However, the number of myelin nerve fibers of the facial nerve of the rabbits was similar when compared to the control and treatment groups, in both evaluation periods.
  41. ncbi Intraoperative diagnosis of facial nerve schwannoma at parotidectomy
    Ritvik P Mehta
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Am J Otolaryngol 29:126-9. 2008
    Our objective was to provide a diagnostic algorithm for facial nerve schwannomas presenting as a parotid mass.
  42. ncbi Facial nerve in rhytidoplasty: anatomic study of its trajectory in the overlying skin and the most common sites of injury
    Rolando Zani
    Morphologic Department, Federal University of Sao Paulo, Escola Paulista de Medicina, Al Joaquim E de Lima 835, ap 111, São Paulo SP Brazil 01403 001
    Ann Plast Surg 51:236-42. 2003
    The anatomic study of the facial nerve is closely related to the prevention of nerve injury that may occur in facial surgeries...
  43. ncbi Effects of facial nerve injury on mouse motoneurons lacking the p75 low-affinity neurotrophin receptor
    C C Ferri
    Department of Physiology, Queen s University, Kingston, Ontario, Canada
    J Neurobiol 34:1-9. 1998
    ..In adult p75 (-/-) mice, functional recovery of whiskers movement following a facial nerve crush occurred slightly earlier than in p75 (+/+) mice, and some recovery of function over a 25-day interval ..
  44. ncbi Intratemporal facial nerve transfer with direct coaptation to the hypoglossal nerve
    Willem P Godefroy
    Department of Otorhinolaryngology, Leiden University Medical Centre, Leiden, The Netherlands
    Otol Neurotol 28:546-50. 2007
    To evaluate functional recovery after facial-hypoglossal nerve transfer with direct coaptation of the intratemporal part of the facial nerve.
  45. pmc Age and facial nerve axotomy-induced T cell trafficking: relation to microglial and motor neuron status
    Daniel J Dauer
    Department of Psychiatry, McKnight Brain Institute, University of Florida, Gainesville, FL 32610, USA
    Brain Behav Immun 25:77-82. 2011
    Following peripheral axotomy of the facial nerve in mice, T lymphocytes cross the blood-brain-barrier (BBB) into the central nervous system (CNS), where they home to the neuronal cell bodies of origin in the facial motor nucleus (FMN) and ..
  46. ncbi Facial nerve motor-evoked potential monitoring during microvascular decompression for hemifacial spasm
    Masafumi Fukuda
    Department of Neurosurgery, Brain Research Institute, University of Niigata, 1 757 Asahimachi dori, Chuo Ku, Niigata City 951 8585, Japan
    J Neurol Neurosurg Psychiatry 81:519-23. 2010
    To determine whether monitoring facial nerve motor-evoked potentials (FNMEPs) elicited by transcranial electrical stimulation during microvascular decompression (MVD) for hemifacial spasm (HFS) is useful for predicting postoperative ..
  47. ncbi Lyme disease in a child presenting with bilateral facial nerve palsy: MRI findings and review of the literature
    B Vanzieleghem
    Department of Radiology, University Hospital Gent, Belgium
    Neuroradiology 40:739-42. 1998
    We report a 7-year-old boy with neuroborreliosis presenting with headache and bilateral facial nerve palsy. MRI demonstrated tentorial and bilateral facial and trigeminal nerve enhancement.
  48. ncbi Radiologic evidence for absence of the facial nerve in Möbius syndrome
    Harriette T F M Verzijl
    Department of Neurology, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Neurology 64:849-55. 2005
    ..To detail the radiologic findings in Möbius syndrome, in order to clarify its pathogenetic mechanisms...
  49. ncbi Massive infra-clinic invasion of the facial nerve by a myoepithelial carcinoma of the parotid
    Sylvain Moriniere
    Unité d ORL Pédiatrique et de Chirurgie Cervico Faciale, Hopital Clocheville, Centre de Pédiatrie Gatien de Clocheville CHU de TOURS, Centre Hospitalier Universitaire de Tours, Tours, France
    Int J Pediatr Otorhinolaryngol 67:663-7. 2003
    ..The parotid tumour was slightly tender and measured almost 2 cm in diameter. There was no associated facial nerve paralysis despite surgical and histologic evidence of massive facial nerve infiltration...
  50. ncbi Paraganglioma of the facial nerve, a rare differential diagnosis for facial nerve paralysis: case report and review of the literature
    Julian Künzel
    Department of Otorhinolaryngology, Head and Neck Surgery, Erlangen Medical School, University of Erlangen, Waldstrasse 1, 91054, Erlangen, Germany
    Eur Arch Otorhinolaryngol 269:693-8. 2012
    ..A 39-year-old male patient presented with total peripheral facial nerve paralysis...
  51. ncbi Combination of hypoglossal-facial nerve jump graft by end-to-side neurorrhaphy and cross-face nerve graft for the treatment of facial paralysis
    Kazuki Ueda
    Department of Plastic and Reconstructive Surgery, Fukushima Medical University, Fukushima, Japan
    J Reconstr Microsurg 23:181-7. 2007
    ..The expression was natural and included fine muscle movements. Spontaneous recovery of the facial nerve was observed in three patients...
  52. ncbi The value of abnormal muscle response monitoring during microvascular decompression surgery for hemifacial spasm
    Ting Ting Ying
    Department of Neurosurgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, The Cranial Nerve Disease Center of Shanghai, 1665 KongJiang Rd, Shanghai 200092, China
    Int J Surg 9:347-51. 2011
    Abnormal muscle response (AMR) to the electrical stimulation of a branch of facial nerve is a specific electrophysiological feature of primary hemifacial spasm (HFS)...
  53. ncbi Long-term functional outcome in facial nerve graft by fibrin glue in the temporal bone and cerebellopontine angle
    Alexis Bozorg Grayeli
    Department of Otolaryngology and Head and Neck Surgery, Hôpital Beajon, Clichy, France
    Eur Arch Otorhinolaryngol 262:404-7. 2005
    The aim of this study was to evaluate the functional outcome of facial nerve repair with fibrin glue in end-to-end anastomosis and intermediate nerve graft...
  54. ncbi Temporal branch of the facial nerve and its relationship to fascial layers
    Seda T Babakurban
    Department of Otorhinolaryngology, Baskent University, Ankara
    Arch Facial Plast Surg 12:16-23. 2010
    ..to anatomically and definitively describe the topographic relationship of the temporal branch of the facial nerve to the fascial layers and the fat pads, and to create an effective algorithm to define the safest approaches ..
  55. ncbi CT and MR imaging of the normal and pathologic conditions of the facial nerve
    L Jager
    University of Munich, Institute of Clinical Radiology, Klinik Grosshadern, Marchioninistr 15, 81366 Munich, Germany
    Eur J Radiol 40:133-46. 2001
    ..tomography (CT) and magnetic resonance imaging (MRI) are well established imaging modalities to examine the facial nerve as well as the course of the facial nerve itself...
  56. ncbi Anomalous facial nerve canal with cochlear malformations
    L V Romo
    Department of Radiology, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    AJNR Am J Neuroradiol 22:838-44. 2001
    BACKGROUND AND PURPOSE: Anteromedial "migration" of the first segment of the facial nerve canal has been previously identified in a patient with a non-Mondini-type cochlear malformation...
  57. ncbi Normal and pathological findings for the facial nerve on magnetic resonance imaging
    K Al-Noury
    Department of Otolaryngology, King Abdulaziz University, Jeddah, Saudi Arabia
    Clin Radiol 66:701-7. 2011
    To demonstrate the enhanced radiological anatomy and common pathological conditions of the facial nerve by using magnetic resonance imaging (MRI).
  58. ncbi Free vascularized lateral femoral cutaneous nerve graft with anterolateral thigh flap for reconstruction of facial nerve defects
    Takuya Iida
    Division of Plastic and Reconstructive Surgery, Shizuoka Cancer Center, Shizuoka, Japan
    J Reconstr Microsurg 22:343-8. 2006
    Wide resection of a malignant tumor in the parotid gland often results in loss of a long segment of facial nerve, as well as a soft-tissue defect...
  59. ncbi The hypoglossal-facial nerve repair as a method to improve recovery of motor function after facial nerve injury
    Umut Ozsoy
    Department of Anatomy, Akdeniz University Faculty of Medicine, Antalya, Turkey
    Ann Anat 193:304-13. 2011
    Nerve repair after facial nerve injury provides neural input to the distal facial nerve and facial musculature via a variety of motor nerves such as hypoglossal, spinal accessory, masseteric branch of the trigeminal nerve and motor ..
  60. ncbi Effects of pituitary adenylate cyclase-activating polypeptide on facial nerve recovery in the Guinea pig
    Hiromoto Kimura
    Department of Otolaryngology, Akita University School of Medicine, Japan
    Laryngoscope 113:1000-6. 2003
    ..The presence and distribution of PACAP receptors following facial nerve transection were also investigated.
  61. ncbi Primary and non-primary parotid malignancies: comparison of treatment modalities and outcomes
    Sylvain Moriniere
    Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, University Francois Rabelais, Bretonneau Hospital, 4 Bd Tonnellé, 37044, Tours Cedex 1, France
    Eur Arch Otorhinolaryngol 264:1231-7. 2007
    ..performed total parotidectomy (TP) versus superficial parotidectomy (SP), the need for sacrificing the facial nerve and postoperative facial nerve function in the two groups...
  62. ncbi Gross dehiscence of the bone covering the facial nerve in the light of otological surgery
    Yildirim A Bayazit
    Department of Otolaryngology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey
    J Laryngol Otol 116:800-3. 2002
    ..In this study, our purpose was to identify the incidence of facial nerve dehiscence in patients undergoing surgery for a variety of chronic ear diseases...
  63. ncbi Masseteric-facial nerve anastomosis for early facial reanimation
    Federico Biglioli
    Department of Maxillo Facial Surgery, Galeazzi Hospital, University of Milan, Italy
    J Craniomaxillofac Surg 40:149-55. 2012
    Early repair of facial nerve paralysis when cortical neural input cannot be provided by the facial nerve nucleus, is generally accomplished anastomozing the extracranial stump of the facial nerve to a motor donor nerve...
  64. ncbi Pleomorphic adenoma: extracapsular dissection versus partial superficial parotidectomy with facial nerve dissection
    Robert L Witt
    Head and Neck Multidisciplinary Clinic, Helen F Graham Cancer Center, USA
    Del Med J 81:119-25. 2009
    ..versus Partial Superficial Parotidectomy (PSP) differ in terms of tumor recurrence and transient and permanent facial nerve dysfunction. ECD does not dissect the facial nerve...
  65. ncbi Role of postoperative magnetic resonance imaging after microvascular decompression of the facial nerve for the treatment of hemifacial spasm
    Jin Woo Chang
    Department of Neurosurgery and Brain Research Institute, BK 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea
    Neurosurgery 50:720-5; discussion 726. 2002
    ....
  66. ncbi New technique of side-to-end hypoglossal-facial nerve attachment with translocation of the infratemporal facial nerve
    V Darrouzet
    Department of Otorhinolaryngology, University Hospital of Bordeaux, France
    J Neurosurg 90:27-34. 1999
    The goal of this study was to assess the clinical results of hypoglossal-facial nerve attachment (HFA), which was primarily performed in patients following excision of tumors of the cerebellopontine angle...
  67. pmc IL-15 and IL-15R alpha gene deletion: effects on T lymphocyte trafficking and the microglial and neuronal responses to facial nerve axotomy
    Zhi Huang
    McKnight Brain Institute, University of Florida, Gainesville, FL 32608, USA
    Neurosci Lett 417:160-4. 2007
    ..b>Facial nerve axotomy in mice leads to T cell migration across an intact blood-brain-barrier (BBB), and under certain ..
  68. ncbi Schwann-like mesenchymal stem cells within vein graft facilitate facial nerve regeneration and remyelination
    Xuemei Wang
    The State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China
    Brain Res 1383:71-80. 2011
    ..marrow mesenchymal stem cells (MSCs) and transdifferentiated Schwann-like MSCs (tMSCs) in promoting transected facial nerve branches repair in a rabbit model of injury, rabbit tMSCs were induced from bone marrow MSCs, and Schwann cells ..
  69. ncbi Microvascular decompression for hemifacial spasm: long-term results from 114 operations performed without neurophysiological monitoring
    Mark Dannenbaum
    Department of Neurosurgery, Baylor College of Medicine, Houston, Texas 77096, USA
    J Neurosurg 109:410-5. 2008
    Microvascular decompression (MVD) of the facial nerve is an effective treatment for hemifacial spasm (HFS), but the procedure is associated with a significant risk of complications such as hearing loss and facial weakness...
  70. ncbi Intraoperative electrophysiological monitoring in microvascular decompression for hemifacial spasm
    Bor Ren Huang
    Department of Neurosurgery, Chang Gung University and Chang Gung Memorial Hospital, Kweishan, Taoyan, Taiwan
    J Clin Neurosci 16:209-13. 2009
    ..aimed to determine the reliability of (i) intraoperative monitoring by stimulated electromyography (EMG) of the facial nerve to predict the completeness of microvascular decompression (MVD) for hemifacial spasm (HFS), and (ii) brainstem ..
  71. ncbi Intraoperative facial nerve motor evoked potential monitoring during skull base surgery predicts long-term facial nerve function outcomes
    Masafumi Fukuda
    Department of Neurosurgery, Brain Research Institute, University of Niigata, Japan
    Neurol Res 33:578-82. 2011
    This study was designed to clarify whether facial nerve motor evoked potentials (FNMEPs) elicited by transcranial electrical stimulation during skull base surgery are useful for predicting long-term facial nerve function.
  72. ncbi Intraparotid facial nerve schwannoma: case report and literature review
    J De Ceulaer
    Department of Oral and Maxillofacial Surgery, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, Brussels, Belgium
    B-ENT 8:225-8. 2012
    A 68-year-old female presented with a right parotid mass and partial frontal peripheral facial nerve palsy. Pre-operatively, the mass was thought to be benign...
  73. ncbi Post-traumatic peripheral facial nerve palsy: surgical and neuroradiological consideration in five cases of delayed onset
    Michele Rotondo
    Department of Neurological Sciences, Second University of Naples, CTO Hospital, Italy
    Acta Neurochir (Wien) 152:1705-9. 2010
    The facial nerve is frequently injured after head trauma with or without temporal bone fractures...
  74. ncbi Split hypoglossal-facial nerve neurorrhaphy for treatment of the paralyzed face
    Taha Z Shipchandler
    Facial Plastic and Reconstructive Surgery, Department of Otolaryngology, Indiana University Health, Indianapolis, USA
    Am J Otolaryngol 32:511-6. 2011
    ..The goals of this procedure are to minimize tongue morbidity and to provide good facial reinnervation...
  75. ncbi Temporal bone hemangiomas involving the facial nerve
    Oren Friedman
    Department of Otolaryngology Head and Neck Surgery, Thomas Jefferson University, Graduate Hospital, Philadelphia, Pennsylvania, USA
    Otol Neurotol 23:760-6. 2002
    Hemangiomas of the facial nerve are rare tumors that can mimic more common temporal bone tumors such as vestibular schwannomas and facial nerve schwannomas...
  76. ncbi Facial nerve conduction after sclerotherapy in children with facial lymphatic malformations: report of two cases
    Pei Jung Lin
    Department of Neurology, E Da Hospital, I Shou University, Kaohsiung, Taiwan
    Tohoku J Exp Med 211:401-6. 2007
    ..However, when the lesions are limited to the face only, surgical scar and facial nerve injury may impair cosmetics and facial expression...
  77. ncbi The expression of a motoneuron-specific serine protease, motopsin (PRSS12), after facial nerve axotomy in mice
    Toshiaki Numajiri
    Department of Plastic and Reconstructive Surgery, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto 602 8566, Japan
    J Plast Reconstr Aesthet Surg 59:393-7. 2006
    ..the relationship between motopsin and motoneuron function, we investigated the expression of motopsin mRNA in facial nerve nuclei after facial nerve axotomy at the anterior margin of the parotid gland in mice...
  78. ncbi Clinical outcome of continuous facial nerve monitoring during primary parotidectomy
    J E Terrell
    Department of Otolaryngology, University of Michigan, Department of Veterans Affairs, Ann Arbor, USA
    Arch Otolaryngol Head Neck Surg 123:1081-7. 1997
    To assess whether continuous facial nerve monitoring during parotidectomy is associated with a lower incidence of facial nerve paresis or paralysis compared with parotidectomy without monitoring and to assess the cost of such monitoring.
  79. ncbi Preservation of facial nerve function after resection of vestibular schwannoma
    Michael E Sughrue
    Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Ave, San Francisco, CA 94143, USA
    Br J Neurosurg 24:666-71. 2010
    Most data regarding facial nerve function in patients undergoing microsurgical resection of vestibular schwannomas predominantly include series performed at a single institution...
  80. pmc Glucose transporters GLUT4 and GLUT8 are upregulated after facial nerve axotomy in adult mice
    Olga Gomez
    Departamento de Medicina y Cirugia Animal, Universidad CEU Cardenal Herrera, Moncada Valencia, Spain
    J Anat 219:525-30. 2011
    ..glucose transporters GLUT3, GLUT4 and GLUT8 in the facial nucleus of adult mice during the first days after facial nerve axotomy...
  81. ncbi Total-length invasion of the facial nerve by parotid carcinoma ex pleomorphic adenoma
    Takeshi Tsutsumi
    Department of Oto Rhino Laryngology, Dokkyo Medical University Koshigaya Hospital, Minami Koshigaya, Saitama, Japan
    Auris Nasus Larynx 36:618-22. 2009
    A case of parotid carcinoma extending along the facial nerve up to the internal auditory canal is presented...
  82. ncbi A case report of facial nerve hemangioma
    Takenori Miyashita
    Department of Otolaryngology, Faculty of Medicine, Kagawa University, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Auris Nasus Larynx 34:519-22. 2007
    b>Facial nerve hemangioma is a rare benign tumor that originates from the venous plexus surrounding the facial nerve. A case of facial nerve hemangioma in the geniculate ganglion was reported...
  83. ncbi Facial nerve hemangioma: a rare case involving the vertical segment
    Neda Ahmadi
    Department of Otolaryngology Head and Neck Surgery, Georgetown University Hospital, Washington, DC 20007, USA
    Laryngoscope 123:499-502. 2013
    This case report and literature review reports on a rare case of facial nerve hemangioma (FNH) involving the vertical facial nerve (FN) segment, and discusses the clinical presentation, imaging, pathogenesis, and management of these rare ..
  84. pmc Techniques of facial nerve block
    F Schimek
    Eberhard Karls University, Tubingen, Germany
    Br J Ophthalmol 79:166-73. 1995
    The efficacy of different techniques of facial nerve block for cataract surgery was investigated. Forty four patients underwent either modified O'Brien, Atkinson, van Lint, or lid blocks...
  85. ncbi Facial nerve reconstruction using a vascularized lateral femoral cutaneous nerve graft based on the superficial circumflex iliac artery system: an application of the inferolateral extension of the groin flap
    Katsuhiko Kashiwa
    Department of Plastic, Reconstructive and Aesthetic Surgery, Iwate Medical University, Faculty of Medicine, Uchimaru, Morioka, Japan
    J Reconstr Microsurg 26:577-82. 2010
    ..In this study, we used this technique involving a vascularized LFCN combined with a groin flap to reconstruct a facial nerve defect. The patient was a 58-year-old man with a salivary duct carcinoma in the left parotid gland...
  86. ncbi Facial nerve function in carcinoma of the parotid gland
    Chris Terhaard
    Department of Radiotherapy, University Medical Center, UMC Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Eur J Cancer 42:2744-50. 2006
    To analyse, for patients with carcinoma of the parotid gland, the prognostic value for treatment outcome of the function of the facial nerve (NVII), and determining facial nerve dysfunction after treatment.
  87. ncbi Reorganization of vibrissal motor representation following severing and repair of the facial nerve in adult rats
    G Franchi
    Dipartimento di Scienze Biomediche e Terapie Avanzate, Universita di Ferrara, Italy
    Exp Brain Res 131:33-43. 2000
    ..For this purpose experiments were performed on ten male albino rats where the facial nerve on one side was severed, sutured and allowed to regenerate for 6 months...
  88. ncbi Predicting facial nerve invasion by parotid gland carcinoma and outcome of facial reanimation
    M Preis
    Department of Otolaryngology and Head and Neck Surgery, Rabin Medical Center, Beilinson Campus, 49100 Petach Tikva, Israel
    Eur Arch Otorhinolaryngol 267:107-11. 2010
    We sought to define risk factors for facial nerve involvement in parotid gland carcinoma and assess the outcome of facial nerve reanimation...
  89. ncbi Edematous swelling of the facial nerve in Bell's palsy
    N Yanagihara
    Department of Otolaryngology, Takanoko Hospital, Matsyama, Japan
    Acta Otolaryngol 120:667-71. 2000
    Surgical decompression of the intratemporal facial nerve from the geniculate ganglion to the stylomastoid foramen was carried out in 91 patients with Bell's palsy...
  90. ncbi Proteomic analysis of microdissected facial nuclei of the rat following facial nerve injury
    Christian Melle
    Core Unit Chip Application CUCA, Institute of Human Genetics and Anthropology, University Hospital Jena, Jena, Germany
    J Neurosci Methods 185:23-8. 2009
    ..Introducing proteomics to this field, we unilaterally performed a facial nerve axotomy in 13 adult Wistar rats...
  91. ncbi Was Thomasz Drobnik really the first to operate on the facial nerve?
    Robert C van de Graaf
    Department of Plastic Surgery, University Hospital Groningen, Groningen, The Netherlands
    Otol Neurotol 24:686-90. 2003
    Thomasz Drobnik is considered to have been the first to operate on the facial nerve. The original report of this operation has unfortunately never been found...
  92. ncbi Incidence and characteristics of facial nerve stimulation in children with cochlear implants
    Sharon L Cushing
    Cochlear Implant Program, Department of Otolaryngology, The Hospital for Sick Children and the University of Toronto, Toronto, Canada
    Laryngoscope 116:1787-91. 2006
    ..The aims of this study were to accurately measure facial nerve stimulation in pediatric implant users and to determine the characteristics and incidence of this unwanted ..
  93. ncbi A prospective randomised controlled study on efficacies of acupuncture and steroid in treatment of idiopathic peripheral facial paralysis
    Fu Man Tong
    Department of ENT, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, People s Republic of China
    Acupunct Med 27:169-73. 2009
    ..A randomised controlled trial was undertaken to evaluate the efficacy of acupuncture in comparison with steroid in treatment of idiopathic peripheral facial paralysis (Bell's palsy)...
  94. ncbi Induced NG2 expressing microglia in the facial motor nucleus after facial nerve axotomy
    L Zhu
    Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, 117597 Singapore Department of Plastic Surgery, Chang Zheng Hospital, Shanghai 200003, PR China
    Neuroscience 166:842-51. 2010
    ..It is concluded that axotomized FMN showed two types of NG2 expressing cells namely constitutive NG2 cells and induced-NG2 expressing microglia...
  95. ncbi Brain-derived neurotrophic factor supports facial motoneuron survival after facial nerve transection in immunodeficient mice
    Craig J Serpe
    Rehabilitation, Research and Development Service, Hines VA Hospital, 5th and Roosevelt Road, Hines, IL 60141, USA
    Brain Behav Immun 19:173-80. 2005
    ..4, respectively). The second goal of this study was to begin to elucidate if CD4+ T cells produce NTF after facial nerve axotomy...
  96. ncbi Elimination of facial nerve stimulation by reimplantation in cochlear implant subjects
    Rolf Battmer
    Department of Otolaryngology, Medizinische Hochschule, Germany
    Otol Neurotol 27:918-22. 2006
    ..intracochlear electrodes with contacts facing towards the modiolus have limited current flow towards the outer wall of the cochlea and therefore, may reduce the occurrence of facial nerve stimulation (FN) in cochlear implant subjects.
  97. ncbi Predictive factors of long-term facial nerve function after vestibular schwannoma surgery
    John E Fenton
    Departments of Otolaryngology and Neuro otology, St Vincent s Hospital, Sydney, Australia
    Otol Neurotol 23:388-92. 2002
    To assess predictive factors of long-term facial nerve function in a series of patients undergoing vestibular schwannoma surgery and to evaluate the reproducibility of the relevant parameters.
  98. ncbi Effect of neural-induced mesenchymal stem cells and platelet-rich plasma on facial nerve regeneration in an acute nerve injury model
    Hyong Ho Cho
    Department of Otolaryngology Head and Neck Surgery, Chonnam National University Medical School, 8 Hackdong Donggu, 501 190, Gwangju, South Korea
    Laryngoscope 120:907-13. 2010
    The purpose of this study was to investigate the effects of platelet-rich plasma (PRP) and neural-induced human mesenchymal stem cells (nMSCs) on axonal regeneration from a facial nerve axotomy injury in a guinea pig model.
  99. ncbi Facial nerve monitoring parameters as a predictor of postoperative facial nerve outcomes after vestibular schwannoma resection
    Brian A Neff
    College of Medicine, Columbus, Ohio, USA
    Otol Neurotol 26:728-32. 2005
    To evaluate whether the intraoperative stimulus threshold and response amplitude measurements from facial electromyography can predict facial nerve function at 1 year after vestibular schwannoma resection.
  100. ncbi Changes in mRNA for VAMPs following facial nerve transection
    Yong Ho Che
    Department of Anatomy and Neuroscience, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka, Suita, Osaka, Japan
    J Chem Neuroanat 24:147-52. 2002
    ..On the contrary, VAMP1 mRNA, which was abundantly expressed in the control facial nucleus, was transiently decreased from 3 to 21 days after axotomy. Differential regulation of VAMPs may reflect distinct roles in nerve regeneration...
  101. ncbi Facial nerve outcomes in middle cranial fossa vs translabyrinthine approaches
    Brandon Isaacson
    University of Michigan Hospitals, Department of Otolaryngology Head and Neck Surgery, Ann Arbor, MI 48109 0312, USA
    Otolaryngol Head Neck Surg 133:906-10. 2005
    To compare the final facial nerve outcomes between middle cranial fossa (MCF) vs translabyrinthine (TL) resection of size-matched vestibular schwannomas.

Research Grants53

  1. STEROID HORMONES AND NEURONAL REGENERATION
    Kathryn Jones; Fiscal Year: 2001
    ..has identified a role for testosterone propionate (TP) in enhancing neuronal regeneration of the crushed facial nerve in adult hamsters...
  2. CHEMOKINE RECEPTOR EXPRESSION IN THE CNS
    Jeffrey Harrison; Fiscal Year: 2003
    ..g. neonatal facial nerve axotomy and rubrospinal tractotomy. 2...
  3. Psychiatric Co-Morbidity in Facial Nerve Dysfunction
    Karen Schmidt; Fiscal Year: 2007
    ..Award is researching facial signaling and its association with psychiatric morbidity in patients with facial nerve dysfunction...
  4. Immune Regulation of Neuronal Injury and Repair
    KATHRYN JANE JONES; Fiscal Year: 2013
    ..Superimposition of facial nerve axotomy (FNA) on the transgenic mouse model of ALS (SOD1G93A) during pre-symptomatic stages indicates that SOD1 ..
  5. Neural Control of Choroidal Blood Flow
    ANTON J REINER; Fiscal Year: 2013
    ..We have found that the vasodilatory parasympathetic facial nerve input to choroid from the pterygopalatine ganglion appears to maintain high ChBF during low systemic blood ..
  6. Pediatric Percutaneous Cochlear Implantation Clinical Validation &Implementation
    Robert F Labadie; Fiscal Year: 2012
    ..9% avoidance of vital anatomy, specifically the facial nerve. In the attached submission, we propose to translate this technology to the pediatric population...
  7. Clinical Validation and Testing of Percutaneous Cochlear Implantation
    Robert F Labadie; Fiscal Year: 2013
    ..g. the facial nerve) and hit the target-the scala tympani of the cochlea...
  8. International collaborative research to develop quantitive sensory testing guidel
    Mark Drangsholt; Fiscal Year: 2009
    ..in addition to dysfunction of the trigeminal system, damage to taste fibers in the chorda tympani branch of the facial nerve may be related to oral pain conditions...
  9. CFM: Longitudinal Outcomes in Children pre-Kindergarten (CLOCK)
    MATTHEW LOUIS SPELTZ; Fiscal Year: 2013
    ..is frequently associated with malformations of the outer, inner and middle ear, mandible, soft tissue, and facial nerve, resulting in varying degrees of facial asymmetry...
  10. Surgical and Rehabilitative Management of Facial Nerve Injury
    THERESA A HADLOCK; Fiscal Year: 2013
    ..Damage to the facial nerve is particularly disabling because the ability to blink, eat, speak, and communicate through facial expressions ..
  11. Accurate Localization of General Tubular Structures in Medical Images
    JACK NOBLE; Fiscal Year: 2010
    ..a particular algorithm was developed which has performed robustly in localizing two nerves in the ear, the facial nerve and chorda tympani...
  12. AUTONOMIC CONTROL OF LACRIMAL GLAND FUNCTION
    BARRY BROMBERG; Fiscal Year: 1980
    ..Parasympathectomy will be attempted by cauterization of the facial nerve. Chemical sympathectomy will be by systemic release of atropine from subcutaneous or intraperitoneal minipump ..
  13. GUSTATORY CHEMOSENSITIVITY OF THE ORAL PALATE
    INGLIS MILLER; Fiscal Year: 1980
    ..of the rat is examined by recording summated nerve response from the greater superficial petrosal branch of the facial nerve while chemical solutions are applied to the palatine surface...
  14. STUDIES OF THE PATHOPHYSIOLOGY OF HEMIFACIAL SPASM
    Aage Moller; Fiscal Year: 1990
    Classical hemifacial spasm (HFS) is in the majority of cases caused by cross-compression of the facial nerve near its entrance to the brainstem by a blood vessel, but its pathophysiology is largely unknown...
  15. AUTONOMIC CONTROL OF OCULAR BLOOD FLOW
    Michael Koss; Fiscal Year: 1999
    ..are designed to systematically study neurogenic vasodilator mechanisms with emphasis on input from the facial nerve and on the possibility that NO is ultimately responsible for ocular vasodilation at the vascular level...
  16. Blink Prosthesis for Facial Paralysis Patients
    Daniel McDonnall; Fiscal Year: 2010
    ..is to create an implantable stimulator device to restore functional eye blink in patients with unilateral facial nerve paralysis...
  17. Fully Implantable Eye Blink Motor Neuroprosthesis for Facial Nerve Paralysis
    Daniel McDonnall; Fiscal Year: 2006
    ..is to create a totally implantable stimulator device that can restore eye blink in patients with unilateral facial nerve paralysis...
  18. MECHANISMS OF TROPHIN AND TOXIN ELABORATION BY MICROGLIA
    Stella Elkabes; Fiscal Year: 2001
    ..Two models of injury that induce different microglial and neuronal reactions, the facial nerve transection and toxic ricin injection will be employed to investigate the regulation of microglial trophin ..
  19. DIODE LASER SYSTEM FOR FEEDBACK-CONTROLLED TISSUE WELD
    ROBERT REDIKER; Fiscal Year: 1993
    ..In cancer therapy, removal of tumors in head and neck region frequently requires subsequent repair of the facial nerve. In reconstructive surgery of the hand after trauma, multiple microanastomoses are needed...
  20. An ENU screen of the mouse genome for new of ALS
    John Roder; Fiscal Year: 2003
    ..Axon counts will be made on the facial nerve and the L4 ventral roots...
  21. LONG TERM NERVE REGENERATION THROUGH COLLAGEN DEVICES
    Ioannis Yannas; Fiscal Year: 2001
    ..oncological surgery to remove tumors in the cranial base requires transection, and often resection, of the facial nerve. Current clinical treatments have led to incomplete and unsatisfactory recovery of motor and sensory function...
  22. LONG TERM NERVE REGENERATION THROUGH COLLAGEN DEVICES
    Ioannis Yannas; Fiscal Year: 2002
    ..oncological surgery to remove tumors in the cranial base requires transection, and often resection, of the facial nerve. Current clinical treatments have led to incomplete and unsatisfactory recovery of motor and sensory function...
  23. AGE, AXON INJURY AND MOTOR NEURON SYNAPTOLOGY
    DEBORAH VAUGHAN; Fiscal Year: 1993
    ..to examine the changing synaptic relationships of injured facial motor neurons following crush injury of the facial nerve in young (3 month) and middle aged (15 month) rats...
  24. MECHANISMS UNDERLYING MOTOR CORTEX PLASTICITY
    GEORGE HUNTLEY; Fiscal Year: 2000
    ..the forelimb/vibrissa border region contains overlapping distribution of output neurons to the spinal cord and facial nerve nucleus which could represent the anatomical basis for intracortical microstimulation (ICMS)-defected border ..
  25. MOLECULAR MECHANISMS OF MICROGLIAL ACTIVATION
    Wolfgang Streit; Fiscal Year: 1999
    ..The first aim is to measure the cytokines produced by microglia during the regeneration of the facial nerve neurons following axotomy and during rubrospinal nucleus neuronal degeneration following lateral funiculotomy...
  26. Surgical Management of Facial Nerve Injury
    Theresa Hadlock; Fiscal Year: 2007
    ..unreadable] [unreadable] The immediate basic scientific goals are to develop an animal model for the study of facial nerve regeneration, to control the phenomenon of aberrant regeneration (misrouting of axons to an inappropriate ..
  27. Genetic Analysis of Age Related Hearing Impairment
    Rick A Friedman; Fiscal Year: 2010
    ..This improved knowledge base can be anticipated to constitute fertile ground for developing new evidence-based preventive and therapeutic approaches to treating ARHI. ..
  28. Androgens and molecular mediators of motoneuron repair
    KEITH FARGO; Fiscal Year: 2008
    ..This research could potentially lead to future treatment strategies for traumatic nerve injuries and neurodegenerative diseases. [unreadable] [unreadable]..
  29. Study of a genetic network involved in ear development
    Rick Friedman; Fiscal Year: 2005
    ..These and future experiments represent the natural progression from my Mentored Clinical Scientist Development Award (K08). ..
  30. DEVELOPMENT OF THE GUSTATORY SYSTEM
    RICHARD NORTHCUTT; Fiscal Year: 2005
    ..To test the hypothesis that retinoic acid acts as a signal to pattern endoderm directly during gastrulation (aim 3), presumptive pharyngeal endoderm will be excised, exposed to retinoic acid, and cultured. ..
  31. Gene Expression in Acute and Chronic Neurologic Disease
    Donald Gilden; Fiscal Year: 2008
    ..This concerted effort is focused on prospective studies to delineate the cause, pathogenesis and eventual prevention of viral and demyelinating diseases of the human nervous system. ..
  32. GENE EXPRESSION IN ENTAMOEBA HISTOLYTICA
    William Petri; Fiscal Year: 2008
    ..Successful completion of these studies will provide insight into transcription regulation of virulence factors by the novel mechanism of direct calcium control of an EF-hand containing transcription factor. ..
  33. Developmental control of cell polarity in vertebrate embryos.
    John B Wallingford; Fiscal Year: 2010
    ..Together, these experiments will help us to understand how PCP signaling influences such diverse cellular processes as convergent extension and ciliogenesis. ..
  34. Nitogen reduction and xenobiotic response
    Lauren A Trepanier; Fiscal Year: 2010
    ..The ultimate goal of these studies is to find better ways to prevent these adverse reactions. ..
  35. PKA modulation of hedgehog: a mouse medulloblastoma model
    James Waschek; Fiscal Year: 2009
    ..abstract_text> ..
  36. Immunodeficiency and Neuronal Function
    JOHN PETITTO; Fiscal Year: 2008
    ....
  37. RPE-Mphi Binding: Ca++_&O2-_Dependent AMD Responses
    Victor Elner; Fiscal Year: 2008
    ..This new knowledge is likely to lead to advances in therapy, which may stem or prevent AMD. ..
  38. Gene Targeting to Study Light-induced Circadian Changes
    James Waschek; Fiscal Year: 2003
    ..Moreover, the same targeting system should have utility in investigating individual components of the clock, such as PER, CRY, BMAL and CLOCK proteins. ..
  39. ADHERENCE BLOCKING VACCINE FOR AMEBIASIS
    William Petri; Fiscal Year: 2003
    ..In Project 3, the applicants will attempt to develop a novel adjuvant, based on the ricin B subunit to improve the immunogenicity of proteins in plants. ..
  40. Herpesviruses in Vestibular Neuritis
    JEFFREY VRABEC; Fiscal Year: 2003
    ..This information can help determine why some individuals with latent virus in the vestibular ganglion develop clinical symptoms due to reactivation and some do not. ..
  41. Neuroimmunology of IL-15
    JOHN PETITTO; Fiscal Year: 2004
    ..abstract_text> ..
  42. Methylphenidate & gene expression in the rat brain.
    JOAN BAIZER; Fiscal Year: 2004
    ..abstract_text> ..
  43. CLINICAL CHARACTERIZATION&GENETICS OF OPTIC NERVE DRUSEN
    Bradley Katz; Fiscal Year: 2005
    ..These data may suggest novel therapies to prevent the visual field loss associated with OND. In addition, these data may yield information about other diseases of the optic nerve. ..
  44. ANTIGENIC DETERMINANTS OF VARICELLA VIRUS
    Charles Grose; Fiscal Year: 2006
    ..These proposed VZV studies will provide further insight into the multiple functions of gE and the gE:gI complex. ..
  45. Regulation of Neural Precursors: Role of Neuropeptides
    James Waschek; Fiscal Year: 2006
    ..The work may lead to new strategies for the diagnosis and treatment of diseases of brain development, degenerative diseases and brain tumors. ..
  46. Ethanol, neurotrophins, and thalamocortical matching
    SANDRA MOONEY; Fiscal Year: 2006
    ..abstract_text> ..
  47. Bell's Palsy-Randomized Clinical Trial
    John Neely; Fiscal Year: 2007
    ..palsy, the sudden onset of unilateral facial paralysis without identifiable cause involving all branches of the facial nerve, affects approximately 23/100,000 people each year. Herpes simplex virus, type 1, is the putative etiology...
  48. Rapid Diagnostics for Category B Enteropathogens
    William Petri; Fiscal Year: 2007
    ..Successful completion of these studies will yield high throughput diagnostic tests that target multiple enteropathogens simultaneously in a single sample. ..
  49. Replacing an Animal Resource Facility Cage Washer.
    Kristen Drescher; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  50. Sustained Release Inner Ear Delivery of Corticosteroid
    William Slattery; Fiscal Year: 2007
    ..This system could also be used for other drugs where chronic delivery is essential. [unreadable] [unreadable] [unreadable]..
  51. Training Program in Integrative Immunobiology
    Virginia Sanders; Fiscal Year: 2007
    ..In summary, we will provide a multidisciplinary training environment unlike any other for studying the basic science and clinical applications of the immune system in health and disease. ..
  52. The Role of Glutamate and CCK in the PBN in Taste Reactivity
    Michael King; Fiscal Year: 2007
    ..Specifically, data collected during the proposed investigation will determine if glutamate and CCK in the PBN play a critical role in the assessment of ingested substances and subsequent behavioral responses. ..
  53. IL-2 GENE DELETION: NEURODEVELOPMENT AND BEHAVIOR
    JOHN PETITTO; Fiscal Year: 2002
    ..We believe that the proposed research is timely and will lay an essential foundation on which to build in future studies. ..