cranial nerves

Summary

Summary: Twelve pairs of nerves that carry general afferent, visceral afferent, special afferent, somatic efferent, and autonomic efferent fibers.

Top Publications

  1. ncbi Imaging of the lower cranial nerves
    Fred J Laine
    Magn Reson Imaging Clin N Am 10:433-49. 2002
  2. ncbi Anatomical details of the brainstem and cranial nerves visualized by high resolution readout-segmented multi-shot echo-planar diffusion-weighted images using unidirectional MPG at 3T
    Shinji Naganawa
    Department of Radiology, Nagoya University Graduate School of Medicine, Japan
    Magn Reson Med Sci 10:269-75. 2011
  3. ncbi Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox gene Hox-1.6
    O Chisaka
    Howard Hughes Medical Institute, Department of Human Genetics, University of Utah School of Medicine, Salt Lake City 84112
    Nature 355:516-20. 1992
  4. ncbi A clinical study of the involvement of cranial nerves in leprosy
    D V Gopinath
    Department of Dermatology and STD, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry 605 006, India
    Indian J Lepr 76:1-9. 2004
  5. ncbi Patterning and axon guidance of cranial motor neurons
    Sarah Guthrie
    MRC Centre for Developmental Neurobiology, King s College, Guy s Campus, London, SE1 1UL, UK
    Nat Rev Neurosci 8:859-71. 2007
  6. ncbi Transcranial magnetic stimulation of motor pathways directed to muscles supplied by cranial nerves in amyotrophic lateral sclerosis
    Maria Teresa Desiato
    Clinica Neurologica, Dipartimento di Neuroscienze, Universita Tor Vergata, Ospedale S Eugenio, Piazzale Umanesimo, 10, 00144 Rome, Italy
    Clin Neurophysiol 113:132-40. 2002
  7. ncbi Twist is required for patterning the cranial nerves and maintaining the viability of mesodermal cells
    Masato S Ota
    Embryology Unit, Children s Medical Research Institute, Westmead, NSW Australia
    Dev Dyn 230:216-28. 2004
  8. ncbi Three-dimensional in vivo modeling of vestibular schwannomas and surrounding cranial nerves with diffusion imaging tractography
    David Qixiang Chen
    Division of Neurosurgery, Toronto Western Hospital and University of Toronto, Toronto, Ontario, Canada
    Neurosurgery 68:1077-83. 2011
  9. ncbi Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain
    S Schneider-Maunoury
    Unité 368 de l Institut National de la Santé et de la Recherche Médicale, Biologie Moléculaire du Développement, Ecole Normale Superieure, Paris, France
    Cell 75:1199-214. 1993
  10. ncbi Driven equilibrium (drive) MR imaging of the cranial nerves V-VIII: comparison with the T2-weighted 3D TSE sequence
    E Ciftci
    School of Radiology, University of Kocaeli, Derince, 41100, Turkey
    Eur J Radiol 51:234-40. 2004

Research Grants

  1. Human in Mouse Modeling of HNSCC to Predict Resonse to Therapy
    Wendell G Yarbrough; Fiscal Year: 2010
  2. Genetic Regulation of Rhombomere Formation
    CHARLES G SAGERSTROM; Fiscal Year: 2013
  3. Prediction of Physiological Events in People with Sleep Disordered Breathing
    Jonathan A Waxman; Fiscal Year: 2011
  4. Fibulin-1 Regulation of the DiGeorge Syndrome Pathogenesis Pathway
    WILLIAM SCOTT ARGRAVES; Fiscal Year: 2012
  5. Molecular Imaging of Retrograde Nerve Transport
    DAWID NONE SCHELLINGERHOUT; Fiscal Year: 2013
  6. Netrin5 in Mammalian Neurodevelopment
    Robert W Burgess; Fiscal Year: 2013
  7. STRUCTURAL BASIS OF AMBLYOPIA AND STRABISMUS
    Jonathan C Horton; Fiscal Year: 2012
  8. Sensorimotor control of the oropharynx and esophagus
    RODERICK ATKINS SUTHERS; Fiscal Year: 2013
  9. NEURAL REGULATION OF VASOPRESSIN RELEASE
    J Thomas Cunningham; Fiscal Year: 2010
  10. 2010 Conference on neurofibromatosis type 2.
    Marco Giovannini; Fiscal Year: 2010

Detail Information

Publications235 found, 100 shown here

  1. ncbi Imaging of the lower cranial nerves
    Fred J Laine
    Magn Reson Imaging Clin N Am 10:433-49. 2002
    Knowledge of the nuclear origins and the normal course of the cranial nerves, and their functional components, is important in any evaluation of cranial neuropathy...
  2. ncbi Anatomical details of the brainstem and cranial nerves visualized by high resolution readout-segmented multi-shot echo-planar diffusion-weighted images using unidirectional MPG at 3T
    Shinji Naganawa
    Department of Radiology, Nagoya University Graduate School of Medicine, Japan
    Magn Reson Med Sci 10:269-75. 2011
    ..was significantly better than DWI by single-shot EPI for visualizing the medial longitudinal fasciculus, lateral lemniscus, corticospinal tract, and seventh/eighth cranial nerves and offered significantly less distortion of the brainstem.
  3. ncbi Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox gene Hox-1.6
    O Chisaka
    Howard Hughes Medical Institute, Department of Human Genetics, University of Utah School of Medicine, Salt Lake City 84112
    Nature 355:516-20. 1992
    ..in the formation of the external, middle and inner ears as well as in specific hindbrain nuclei, and in cranial nerves and ganglia...
  4. ncbi A clinical study of the involvement of cranial nerves in leprosy
    D V Gopinath
    Department of Dermatology and STD, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry 605 006, India
    Indian J Lepr 76:1-9. 2004
    A clinical descriptive study was conducted to assess the frequency and pattern of involvement of cranial nerves in leprosy and to study the relationship of cranial nerve involvement with a leprosy patch or patches on facial skin...
  5. ncbi Patterning and axon guidance of cranial motor neurons
    Sarah Guthrie
    MRC Centre for Developmental Neurobiology, King s College, Guy s Campus, London, SE1 1UL, UK
    Nat Rev Neurosci 8:859-71. 2007
    ..The recent identification of genes that are mutated in human cranial dysinnervation disorders is now shedding light on the functional consequences of perturbations of cranial motor neuron development...
  6. ncbi Transcranial magnetic stimulation of motor pathways directed to muscles supplied by cranial nerves in amyotrophic lateral sclerosis
    Maria Teresa Desiato
    Clinica Neurologica, Dipartimento di Neuroscienze, Universita Tor Vergata, Ospedale S Eugenio, Piazzale Umanesimo, 10, 00144 Rome, Italy
    Clin Neurophysiol 113:132-40. 2002
    ....
  7. ncbi Twist is required for patterning the cranial nerves and maintaining the viability of mesodermal cells
    Masato S Ota
    Embryology Unit, Children s Medical Research Institute, Westmead, NSW Australia
    Dev Dyn 230:216-28. 2004
    ....
  8. ncbi Three-dimensional in vivo modeling of vestibular schwannomas and surrounding cranial nerves with diffusion imaging tractography
    David Qixiang Chen
    Division of Neurosurgery, Toronto Western Hospital and University of Toronto, Toronto, Ontario, Canada
    Neurosurgery 68:1077-83. 2011
    Preservation of cranial nerves (CNs) is of paramount concern in the treatment of vestibular schwannomas, particularly in large tumors with thinned and distorted CN fibers...
  9. ncbi Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain
    S Schneider-Maunoury
    Unité 368 de l Institut National de la Santé et de la Recherche Médicale, Biologie Moléculaire du Développement, Ecole Normale Superieure, Paris, France
    Cell 75:1199-214. 1993
    ..Anatomical analysis of the hindbrain and of the cranial nerves during embryogenesis, combined with the determination of the expression patterns of rhombomere-specific genes, ..
  10. ncbi Driven equilibrium (drive) MR imaging of the cranial nerves V-VIII: comparison with the T2-weighted 3D TSE sequence
    E Ciftci
    School of Radiology, University of Kocaeli, Derince, 41100, Turkey
    Eur J Radiol 51:234-40. 2004
    ..The aim of this study is to evaluate the efficacy of the driven equilibrium radio frequency reset pulse (DRIVE) on image quality and nerve detection when used in adjunction with T2-weighted 3D turbo spin-echo (TSE) sequence...
  11. ncbi Intraoperative monitoring of lower cranial nerves in skull base surgery: technical report and review of 123 monitored cases
    Cahide Topsakal
    Firat University School of Medicine, Elazig, Turkey
    Neurosurg Rev 31:45-53. 2008
    ..Injury to the lower cranial nerves (LCN; CN 9-12) profoundly affects a patient's quality of life...
  12. ncbi A clear map of the lower cranial nerves at the superior carotid triangle
    Daniel D Cavalcanti
    Division of Neurological Surgery, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona, USA
    World Neurosurg 74:188-94. 2010
    The lower cranial nerves must be identified to avoid iatrogenic injury during skull base and high cervical approaches. Prompt recognition of these structures using basic landmarks could reduce surgical time and morbidity.
  13. ncbi US Food and Drug Administration/Conformit Europe-approved absorbable nerve conduits for clinical repair of peripheral and cranial nerves
    M F Meek
    Pulvertaft Hand Centre, Derby, United Kingdom
    Ann Plast Surg 60:110-6. 2008
    ..by the US Food and Drug Administration (FDA) and Conformit Europe (CE) for clinical repair of peripheral and cranial nerves. Surgeons are often not aware of the different (bio)materials of these conduits when performing nerve repair...
  14. pmc Diffusion tensor imaging detects axonal injury and demyelination in the spinal cord and cranial nerves of a murine model of globoid cell leukodystrophy
    A Alex Hofling
    Department of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
    NMR Biomed 22:1100-6. 2009
    ..This first reported application of spinal cord DTI in the setting of GLD holds potential as a noninvasive, quantitative assay of therapeutic efficacy in future treatment studies...
  15. ncbi Peripheral development of cranial nerves in a cyclostome, Lampetra japonica: morphological distribution of nerve branches and the vertebrate body plan
    S Kuratani
    Department of Morphogenesis, Institute of Molecular Embryology and Genetics IMEG, Kumamoto University School of Medicine, Japan
    J Comp Neurol 384:483-500. 1997
    ..This results in a deep position of the cranial nerves, which is not observed in gnathostomes.
  16. pmc Loss of the Sall3 gene leads to palate deficiency, abnormalities in cranial nerves, and perinatal lethality
    M Parrish
    Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Mol Cell Biol 24:7102-12. 2004
    ..5. In E10.5 embryos, deficiencies in cranial nerves that normally innervate oral structures, particularly the glossopharyngeal nerve (IX), were observed...
  17. ncbi Diffusional anisotropy in cranial nerves with maturation: quantitative evaluation with diffusion MR imaging in rats
    M Takahashi
    Department of Radiology, University of Pennsylvania Medical Center, Philadelphia 19104, USA
    Radiology 216:881-5. 2000
    ....
  18. ncbi Key roles of retinoic acid receptors alpha and beta in the patterning of the caudal hindbrain, pharyngeal arches and otocyst in the mouse
    V Dupé
    Institut de Genetique et de Biologie Moleculaire et Cellulaire IGBMC, CNRS INSERM ULP College de France, B P 163, CU de Strasbourg, France
    Development 126:5051-9. 1999
    ..Int. J. Dev. Biol. 41, 425-447). In a search for neural crest defects, we have analysed the rhombomeres, cranial nerves and pharyngeal arches of these double null mutants at early embryonic stages...
  19. ncbi The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system
    Karen Niederreither
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP College de France, BP 10142, 67404 Illkirch Cedex, CU de Strasbourg, France
    Development 130:2525-34. 2003
    ..Patterning and axonal outgrowth of the posterior (9th-12th) cranial nerves is also altered...
  20. ncbi Hes1 and Hes5 regulate the development of the cranial and spinal nerve systems
    Jun Hatakeyama
    Institute for Virus Research, Kyoto University, Kyoto, Japan
    Dev Neurosci 28:92-101. 2006
    ..These results indicate that Hes1 and Hes5 play an important role in the formation of the cranial and spinal nerve systems...
  21. ncbi Imaging the cranial nerves: part II: primary and secondary neoplastic conditions and neurovascular conflicts
    Alexandra Borges
    Radiology Department, Instituto Portugues de Oncologia Francisco Gentil Centro de Lisboa, Rua Professor Lima Basto, 1093 Lisboa Codex, Portugal
    Eur Radiol 17:2332-44. 2007
    ..to provide high quality multiplanar and curved reconstructions that can follow the often complex course of cranial nerves. Seeking the cause of a cranial nerve deficit is a common indication for imaging, and it is not uncommon that ..
  22. pmc Cornichon-like protein facilitates secretion of HB-EGF and regulates proper development of cranial nerves
    Hideharu Hoshino
    Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University, Kyoto 606 8502, Japan
    Mol Biol Cell 18:1143-52. 2007
    ..This phenotype closely resembled that of ErbB4 knockout mouse embryos. Because HB-EGF was uniformly expressed in the embryonic hindbrain, CNIL seems to confine the site of HB-EGF action to r3 and r5 in concert with ErbB4...
  23. ncbi Morphological abnormalities of embryonic cranial nerves after in utero exposure to valproic acid: implications for the pathogenesis of autism with multiple developmental anomalies
    Yasura Tashiro
    Department of Anatomy II, Graduate School of Medicine, Mie University, 2 174 Edobashi, Tsu City, Mie, Japan
    Int J Dev Neurosci 29:359-64. 2011
    ..In the present study, to investigate the development of peripheral cranial nerves for use in an animal model of autism, rat embryos were treated with valproic acid (VPA) in utero and their ..
  24. ncbi Motor responses of muscles supplied by cranial nerves to subthalamic nucleus deep brain stimuli
    Joao Costa
    Department of Neurology, Santa Maria University Hospital, Institute of Molecular Medicine, Lisbon Faculty of Medicine Lisbon, Portugal
    Brain 130:245-55. 2007
    ..These findings are relevant in the discussion of the innervation of upper and lower facial muscles in humans and in the interpretation of previous results obtained with transcranial cortical stimulation...
  25. ncbi FoxN3 is required for craniofacial and eye development of Xenopus laevis
    Maximilian Schuff
    Abteilung Biochemie, Universitat Ulm, Ulm, Germany
    Dev Dyn 236:226-39. 2007
    ..in Xenopus laevis, leads to an abnormal formation of the jaw cartilage, absence or malformation of distinct cranial nerves, and reduced size of the eye...
  26. ncbi Localized transcranial electrical motor evoked potentials for monitoring cranial nerves in cranial base surgery
    Ryojo Akagami
    Division of Neurosurgery, Department of Surgery, Vancouver General Hospital, Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
    Neurosurgery 57:78-85; discussion 78-85. 2005
    ..To describe a novel monitoring technique that allows "functional" assessment of cranial nerve continuity during cranial base surgery...
  27. ncbi Assessing risk factors for postoperative nausea and vomiting: a retrospective study in patients undergoing retromastoid craniectomy with microvascular decompression of cranial nerves
    Li Meng
    Department of Anesthesiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Neurosurg Anesthesiol 18:235-9. 2006
    We have observed that patients, after retromastoid craniectomy (RMC) with microvascular decompression (MVD) of cranial nerves, frequently experienced postoperative nausea and vomiting (PONV)...
  28. ncbi Continuous electromyography monitoring of motor cranial nerves during cerebellopontine angle surgery
    J Romstock
    Department of Neurosurgery, University of Erlangen Nuremberg, Germany
    J Neurosurg 93:586-93. 2000
    ..The aim of this study was to provide a detailed analysis of intraoperative EMG phenomena with respect to their surgical significance...
  29. ncbi Relationship between the number of involved cranial nerves and the percentage of lesions located in the cavernous sinus
    Chou Ching K Lin
    Neurology, National Cheng Kung University Hospital, 138 Sheng Li Road, Tainan, Taiwan, ROC
    Eur Neurol 49:98-102. 2003
    The main objective of this study is to investigate the relationship between the number of cranial nerves passing through the cavernous sinus affected by a lesion and the percentage of lesions located in the cavernous sinus itself...
  30. ncbi Involvement of the cranial nerves and their nuclei in spinocerebellar ataxia type 2 (SCA2)
    K Gierga
    Institute of Clinical Neuroanatomy, J W Goethe University, Theodor Stern Kai 7, 60590, Frankfurt Main, Germany
    Acta Neuropathol 109:617-31. 2005
    Although the cranial nerves, their nuclei and related fiber tracts are crucial for a variety of oculomotor, somatomotor, somatosensory, auditory, vestibular-related, autonomic and ingestion-related functions, knowledge regarding the ..
  31. ncbi Magnetic resonance imaging of the cranial nerves in the posterior fossa: a comparative study of t2-weighted spin-echo sequences at 1.5 and 3.0 tesla
    F Fischbach
    Department of Radiology, Otto von Guericke University, Medical School, Magdeburg, Germany
    Acta Radiol 49:358-63. 2008
    ..0 Tesla (T) is rapidly gaining clinical acceptance. Whether doubling of the field strength of 1.5T and the subsequent increase in signal-to-noise ratio (SNR) leads to a significant improvement of image quality is not automatically given...
  32. ncbi Dose-response tolerance of the visual pathways and cranial nerves of the cavernous sinus to stereotactic radiosurgery
    K A Leber
    Department of Neurosurgery, Karl Franzens University, School of Medicine, Graz, Austria
    J Neurosurg 88:43-50. 1998
    ..As the number of patients treated with stereotactic radiosurgery increases, it becomes particularly important to define with precision adverse effects on distinct structures of the nervous system...
  33. ncbi Magnetic resonance imaging of the extraocular muscles and corresponding cranial nerves in patients with special forms of strabismus
    Yong hong Jiao
    Beijing Tongren Eye Centre, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
    Chin Med J (Engl) 122:2998-3002. 2009
    ..This study was designed to delineate the MRI characteristics in patients with special forms of strabismus...
  34. ncbi US Food and Drug Administration /Conformit Europe- approved absorbable nerve conduits for clinical repair of peripheral and cranial nerves
    M F Meek
    Pulvertaft Hand Center, Derby, United Kingdom
    Ann Plast Surg 60:466-72. 2008
    ..by the US Food and Drug Administration (FDA) and Conformit Europe (CE) for clinical repair of peripheral and cranial nerves . Surgeons are often not aware of the different(bio) materials of these conduits when performing nerve repair...
  35. ncbi [Leptomeningitis carcinomatosa with progressive involvement of the cranial nerves--report of two cases]
    Marek Babiuch
    II Kliniki Neurologii Instytutu Psychiatrii i Neurologii w Warszawie
    Neurol Neurochir Pol 36:581-6. 2002
    This paper reports two cases of leptomeningitis carcinomatosa with progressive cranial nerves injury as the first clinical sign of disseminated disease. Neurological state, diagnostic procedure and treatment are described.
  36. ncbi Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch
    A Gavalas
    Institut de Génétique et de Biologie Moléculaire and Cellulaire, CNRS INSERM ULP, College de France, BP 163 67404 Illkirch Cedex, CU de Strasbourg, France
    Development 125:1123-36. 1998
    ..labelling of motor neurons indicated that Hoxa1 and Hoxb1 synergise in patterning the VIIth through XIth cranial nerves. The second arch expression of neural crest cell markers was abolished or dramatically reduced, suggesting a ..
  37. ncbi The facial nerve in medial acoustic neuromas
    Christian Strauss
    Department of Neurosurgery, University of Erlangen Nuremberg, Erlangen, Germany
    J Neurosurg 97:1083-90. 2002
    ....
  38. ncbi Functional localization of brainstem and cervical spinal cord nuclei in humans with fMRI
    Barry R Komisaruk
    Department of Psychology, Rutgers, The State University of New Jersey, Newark 07102, USA
    AJNR Am J Neuroradiol 23:609-17. 2002
    ..Our purpose was to use 1.5-T functional MR imaging (fMRI) to visualize the location of cranial nerve (CN) nuclei and other pontine, bulbar, and cervical spinal cord nuclei by using specific sensory stimulation or motor performance...
  39. ncbi Imaging of the upper cranial nerves I, III-VIII, and the cavernous sinuses
    Mauricio Castillo
    Department of Radiology, University of North Carolina School of Medicine, 3326 Old Infirmary Building, CB 7510, Chapel Hill, NC 27599 7510, USA
    Magn Reson Imaging Clin N Am 10:415-31, v. 2002
    This article discusses the upper cranial nerves (I, III-VIII) and their anatomy as it pertains to intra-axial nuclei and tracts, cisternal portions, and extracranial portions...
  40. ncbi Bilateral involvement of a single cranial nerve: analysis of 578 cases
    James R Keane
    Department of Neurology, University of Southern California Medical School, Los Angeles, CA, USA
    Neurology 65:950-2. 2005
    ..inpatients in a large municipal hospital to analyze the seats and causes of involvement of single pairs of cranial nerves. Among 578 cases, the sixth (n = 234) and second (211) nerves predominated, followed by the fourth (48), ..
  41. ncbi Treatment of a partially thrombosed giant aneurysm of the vertebral artery by aneurysm trapping and direct vertebral artery-posterior inferior cerebellar artery end-to-end anastomosis: technical case report
    Ludwig Benes
    Department of Neurosurgery, Philipps University Medical Center, Marburg, Germany
    Neurosurgery 59:ONSE166-7; discussion ONSE166-7. 2006
    ....
  42. ncbi Prevalence and distribution of HSV-1, VZV, and HHV-6 in human cranial nerve nuclei III, IV, VI, VII, and XII
    Diethilde Theil
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    J Med Virol 74:102-6. 2004
    ..The absence of LAT in the samples positive for HSV-1 and the distribution of HSV-1 and HHV-6 do not support the hypothesis that idiopathic cranial nerve palsies result from viral reactivation in the brainstem nuclei...
  43. ncbi Combined subtemporal and retrosigmoid keyhole approach for extensive petroclival meningioma surgery: report of experience with 7 cases
    W Zhu
    Department of Neurosurgery, Huashan Hospital of Fudan University, Shanghai Neurosurgical Center, Shanghai, P R China
    Minim Invasive Neurosurg 50:106-10. 2007
    ..Our experience of 7 cases using a combined subtemporal and retrosigmoid keyhole approach surgery was evaluated for the treatment of extensive petroclival meningiomas...
  44. ncbi Brainstem dysgenesis: report of five patients with congenital hypotonia, multiple cranial nerve involvement, and ocular motor apraxia
    Manuel Roig
    Secció de Neurologia Infantil, Hospital Universitari Vail d Hebron, Barcelona, Spain
    Dev Med Child Neurol 45:489-93. 2003
    ..Intelligence or developmental quotients are within the normal range for their age. Facial hypomimia, feeding, and speech articulatory performance difficulties are the main disabilities observed in these patients at follow-up...
  45. ncbi The cranial nerve exam. Its importance and how to complete it in 3 minutes
    David Miller
    Las Vegas Instititute for Advanced Dental Studies, USA
    Funct Orthod 24:14-9. 2007
  46. ncbi Hypertrophic cranial nerve roots in CIDP
    H Inoue
    Neurology 63:1481. 2004
  47. ncbi [The sphenoid bone: anatomy]
    J W Casselman
    A Z St Jan Brugge A V, Bruges, Belgique
    J Neuroradiol 30:201-10. 2003
    ..The osseous anatomy can be studied using CT. On the other hand, MR is mandatory for visualization of the vascular and nervous structures in and around the sphenoid bone...
  48. ncbi A dynamic regulation of GDNF-family receptors correlates with a specific trophic dependency of cranial motor neuron subpopulations during development
    A Mikaels
    Laboratory of Molecular Neurobiology, MBB, Karolinska Institute, S171 77 Stockholm, Sweden
    Eur J Neurosci 12:446-56. 2000
    ..Our results indicate that specific GDNF family ligands support selective muscle-motor neuron circuits during development...
  49. pmc Time-specific effects of ethanol exposure on cranial nerve nuclei: gastrulation and neuronogenesis
    Sandra M Mooney
    Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Exp Neurol 205:56-63. 2007
    ..Thus, prenatal exposure to ethanol affects the number of neurons in brainstem nuclei in a time-dependent manner. Windows of vulnerability coincide with gastrulation (G7/G8) and the period of neuronal generation (G12/G13)...
  50. ncbi Preservation of cranial nerve function following Gamma Knife radiosurgery for benign skull base meningiomas: experience in 121 patients with follow-up of 5 to 9.8 years
    S Eustacchio
    Department of Neurosurgery, Karl Franzens University, Graz, Austria
    Acta Neurochir Suppl 84:71-6. 2002
    ..In this study we evaluated the effect of Gamma Knife Radiosurgery (GKRS) in 121 patients with benign basal meningiomas after a follow-up of 5 to 9.8 years...
  51. ncbi Thickening and enhancement of multiple cranial nerves in conjunction with cystic white matter lesions in early infantile Krabbe disease
    Lauren A Beslow
    Division of Neurology, The Children s Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA 19104 4399, USA
    Pediatr Radiol 38:694-6. 2008
    ..In addition, the combination of both enlargement and enhancement of multiple cranial nerves in conjunction with unusual cystic lesions adjacent to the frontal horns of the lateral ventricles was ..
  52. ncbi Spinal and cranial hypertrophic neuropathy in multiple sclerosis
    Dianna Quan
    Department of Neurology, University of Colorado Health Sciences Center, Box F727, 4200 East Ninth Avenue, Denver, Colorado 80262, USA
    Muscle Nerve 31:772-9. 2005
    ..These cases suggest that the mechanism of disease in symptomatic central and peripheral demyelination may differ from that of disease in only one region, and that optimal therapy in this situation must be explored further...
  53. ncbi Perineural spread in a case of sinonasal sarcoidosis: case report
    S Mazziotti
    Institute of Radiological Sciences, University of Messina, Policlinico Universitario G. Martino, Via Consolare Valeria Gazzi, 98100 Messina, Italy
    AJNR Am J Neuroradiol 22:1207-8. 2001
    ..We report a case of sinonasal sarcoidosis with perineural spread along the trigeminal and vidian nerves in which primarily MR imaging but also CT allowed excellent visualization of this infiltration...
  54. ncbi [Neurosyphilis revealed by a multiple cranial neuropathy: magnetic resonance imaging findings]
    L Hadrane
    Service de Neurologie, Clinique Sainte Elisabeth, 206, avenue de Fré, 1180 Bruxelles, Belgium
    Rev Neurol (Paris) 164:253-7. 2008
    We report the magnetic resonance imaging (MRI) findings in a case of neurosyphilis revealed by the involvement of two cranial nerves.
  55. ncbi Magnetic resonance imaging findings in chronic inflammatory demyelinating polyneuropathy with intracranial findings and enhancing, thickened cranial and spinal nerves
    H A Kale
    Department of Radiology, Jackson Memorial Hospital, University of Miami, Miami, Florida 33136, USA
    Australas Radiol 51:B21-4. 2007
    ..Magnetic resonance imaging showed presence of an intracranial white matter lesion and enhancing, thickened cranial and spinal nerves. This disorder has been described very infrequently in the radiology literature...
  56. ncbi [Pachymeningitis as a first manifestation of an overlap vasculitic syndrome]
    Carmen Tur
    Med Clin (Barc) 125:479. 2005
  57. pmc Multiple cranial neuropathy and HIV-2
    S Calado
    J Neurol Neurosurg Psychiatry 75:660-1. 2004
  58. ncbi Imaging of the glossopharyngeal, vagus, and accessory nerves
    Theodore C Larson
    Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN 37232 2675, USA
    Semin Ultrasound CT MR 23:238-55. 2002
    The origination and course of the glossopharyngeal, vagus and accessory cranial nerves explains their function and localizes pathology...
  59. ncbi Imaging the cranial nerves: Part I: methodology, infectious and inflammatory, traumatic and congenital lesions
    Alexandra Borges
    Department of Radiology, Instituto Portugues de Oncologia Francisco Gentil Centro de Lisboa, Rua Professor Lima Basto, 1093 Lisboa Codex, Portugal
    Eur Radiol 17:2112-25. 2007
    ..in the depiction of normal anatomy and on infectious and inflammatory, traumatic and congenital pathology affecting the cranial nerves. A detailed discussion of individual cranial nerves lesions is beyond the scope of this article.
  60. ncbi Multiple cranial nerve enhancement: a new MR imaging finding in metachromatic leukodystrophy
    Antonio C M Maia
    AJNR Am J Neuroradiol 28:999. 2007
  61. ncbi Absence of sensory neurons before target innervation in brain-derived neurotrophic factor-, neurotrophin 3-, and TrkC-deficient embryonic mice
    D J Liebl
    Developmental Biology Center, University of Texas Southwestern Medical Center, Dallas, Texas 75235 9133, USA
    J Neurosci 17:9113-21. 1997
    ..We suggest that neurotrophins may function in creating early heterogeneity that would enable ganglia to compensate for diverse modality requirements before the period of naturally occurring death...
  62. ncbi Lemierre's syndrome complicated by carotid thrombosis
    N Maalikjy Akkawi
    Neurological Clinic, University of Brescia, Civil Hospital of Brescia, Italy
    Neurol Sci 22:403-4. 2001
    ..We present an atypical case of Lemierre's syndrome complicated by carotid thrombosis. The etiological factors and the diagnostic and therapeutic measures are discussed...
  63. ncbi [Intraoperative monitoring during skull base surgery]
    Shinjiro Saito
    Department of Neurosurgery, Yamagata University Faculty of Medicine
    Nihon Rinsho 63:347-52. 2005
  64. ncbi Internuclear ophthalmoplegia: causes and long-term follow-up in 65 patients
    I Bolaños
    Department of Neuroophthalmology, Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez, Mexico City, Mexico
    Acta Neurol Scand 110:161-5. 2004
    ..To analyze the causes and long-term clinical outcome of internuclear ophthalmoplegia (INO) in a consecutive series of 65 patients...
  65. ncbi Surgical management of brainstem cavernomas
    M Samii
    Department of Neurosurgery, Nordstadt Hospital, Germany
    J Neurosurg 95:825-32. 2001
    ..CONCLUSIONS: Based on these findings, resection of brainstem cavernomas is the treatment of choice in the majority of these cases because of the high incidence of morbidity related to one or often several brainstem hemorrhages...
  66. ncbi Neuronal expression of peripherin, a type III intermediate filament protein, in the mouse hindbrain
    Meagan Barclay
    Department of Physiology, The University of Auckland, Private Bag 92019, Auckland, New Zealand
    Histochem Cell Biol 128:541-50. 2007
    ..Peripherin immunolabelling was observed in the nerve fibres and nuclei that are associated with all cranial nerves [(CN) V-XII] in the hindbrain...
  67. ncbi [Brain stem encephalitis in childhood]
    I Bodegas
    , Hospital Infantil La Paz, Madrid,
    Rev Neurol 27:71-3. 1998
    ..by ataxia, reduced level of consciousness, involvement of the pyramidal tracts and paralysis of the cranial nerves. No significant information for the diagnosis of either case was obtained from CT...
  68. ncbi Three-dimensional visualization of neurovascular relationships in the posterior fossa: technique and clinical application
    Ramin Naraghi
    Department of Neurological Surgery, Neurocenter and the Division of Neuroradiology, University of Erlangen Nuremberg, Germany
    J Neurosurg 100:1025-35. 2004
    ..The principles and technical details involved in the accurate simultaneous visualization of vessels and cranial nerves as tiny structures are presented using explicit and implicit segmentation as well as volume rendering.
  69. ncbi Resolution of neurogenic arterial hypertension after suboccipital decompression for Chiari malformation. Case report
    Sait Naderi
    Department of Neurosurgery, Faculty of Medicine, Dokuz Eylul University, Inciralti, Izmir, Turkey
    J Neurosurg 102:1147-50. 2005
    ..Resolution of neurogenic arterial hypertension may be expected even in a case of simple suboccipital decompression...
  70. ncbi Anatomy of the brainstem
    Lisa H Smith
    Section of Child Neurology, Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA
    Semin Pediatr Neurol 10:235-40. 2003
    Understanding the anatomy of the brainstem is essential when evaluating disorders of swallowing and breathing. We present a review of the neuroanatomy of the brainstem and related cranial nerves.
  71. ncbi Brainstem cranial-nerve lesions in an infant with hypoxic cerebral injury
    Seiichi Sugama
    Department of Pediatrics, Tokyo Metropolitan Maternity and Child Health Institute, Tokyo, Japan
    Pediatr Neurol 29:256-9. 2003
    ..brainstem injury caused by perinatal hypoxic cerebral injury and exhibited palsy of the lower-brainstem cranial nerves. Magnetic resonance imaging was used to demonstrate lesions of brainstem cranial nerves, which were consistent ..
  72. ncbi Magnetic resonance imaging of the brainstem and cranial nerves III-VII
    Charles Majoie
    Department of Radiology, Academic Medical Center, Amsterdam, The Netherlands
    Mov Disord 17:S17-9. 2002
  73. ncbi Glomus jugulare tumors with intracranial extension
    C Gary Jackson
    The Otology Group at Vanderbilt, Nashville, Tennessee 37203, USA
    Neurosurg Focus 17:E7. 2004
    ..Particular attention will be paid to prevention of cerebrospinal fluid leaks with the use of vascularized tissue for defect reconstruction...
  74. ncbi Cortical control of voluntary blinking: a transcranial magnetic stimulation study
    Y H Sohn
    Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bldg 10 Room 5N226, 10 Center Drive, Bethesda, MD 20892 1428, USA
    Clin Neurophysiol 115:341-7. 2004
    ..To investigate cortical regions related to voluntary blinking...
  75. ncbi Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways
    Francesca Vitelli
    Department of Pediatrics Cardiology, Baylor College of Medicine, Houston, TX 77030, USA
    Hum Mol Genet 11:915-22. 2002
    ..role of neural crest cells in the pathogenesis of the Tbx1 mutant phenotype; however, these cells, and the cranial nerves, are misdirected...
  76. ncbi [HIV related Foix-Chavany-Marie syndrome]
    L Redondo
    Servicio de Neurologia, Hospital Virgen de la Macarena, Sevilla, Spain
    Neurologia 18:741-5. 2003
    Automatic-voluntary motor dissociation of the face and lower cranial nerves of brainstem is the hallmark of Foix-Chavany-Marie syndrome (biopercular syndrome). It is commonly caused by ischemic strokes...
  77. ncbi [Meningo-orbital fold (MOF) as a guiding point in extradural approach to the anterior clinoid process]
    Safwan Bayassi
    Oddział Neurochirurgii i Neurotraumatologii z Pododdziałem Neurospondyliatrii, Wojewódzki Szpital Zespolony w Elblagu, ul Królewiecka 146, 82 300 Elblag, Poland
    Neurol Neurochir Pol 39:49-55. 2005
    ..The goal of the research is to perform a topographic and morphometric study of the meningo-orbital fold...
  78. ncbi Preoperative depiction of cavernous sinus invasion by pituitary macroadenoma using three-dimensional anisotropy contrast periodically rotated overlapping parallel lines with enhanced reconstruction imaging on a 3-tesla system
    Yuichiro Yoneoka
    Department of Neurosurgery, Graduate School of Medical and Dental Sciences, University of Niigata, Japan
    J Neurosurg 108:37-41. 2008
    ..The aim of this study was to identify intracavernous cranial nerves in patients with pituitary macro-adenoma and in healthy volunteers by using 3DAC MR imaging on a 3-tesla ..
  79. ncbi Neuroophthalmological evaluation after Gamma Knife surgery for cavernous sinus meningiomas
    Alberto Franzin
    Gamma Knife Unit, Department of Neurosurgery, San Raffaele Scientific Institute, Milan, Italy
    Neurosurg Focus 23:E10. 2007
    ..The purpose of this study was to assess the role of GKS in the treatment of CSM and to thoroughly analyze the clinical response to GKS...
  80. ncbi Normal cranial nerves in the cavernous sinuses: contrast-enhanced three-dimensional constructive interference in the steady state MR imaging
    Akiko Yagi
    Department of Diagnostic Radiology and Nuclear Medicine, Gunma University School of Medicine, Showa machi, Maebashi Gunma, Japan
    AJNR Am J Neuroradiol 26:946-50. 2005
    Three-dimensional (3D) constructive interference in steady state (CISS) MR imaging is useful for demonstrating cranial nerves (CNs) in the cistern...
  81. ncbi Cavernous sinus anatomy as a basis for interpretation of the clinical picture and radiological investigations in a case of Entomophthorales infection
    C F Hoogendijk
    Department of Oral and Maxillofacial Surgery, University of Pretoria, Pretoria, South Africa
    Clin Anat 19:535-9. 2006
    Several cranial nerves traverse the cavernous sinus producing the typical symptom complex seen during cavernous venous sinus thrombosis in Mucorales infection...
  82. ncbi Is there a place for microvascular decompression?
    A R Møller
    Acta Neurochir (Wien) 147:921-3. 2005
  83. ncbi Surface rendering-based virtual intraventricular endoscopy: retrospective feasibility study and comparison to volume rendering-based approach
    Nobuyuki Nakajima
    Department of Radiology, Brigham and Women s Hospital, Boston, MA, USA
    Neuroimage 37:S89-99. 2007
    ..We sought to develop SR-virtual endoscopy and compared the visibility of anatomical structures in SR and VR using retrospective cases...
  84. ncbi Unusual exophytic subependymoma in the bulbo-cerebellar angle. Case report
    S Romoli
    Department of Neurosciences, Unit of Neurosurgery, University of Pisa, Pisa, Italy
    J Neurosurg Sci 51:81-4. 2007
    ..Neuroradiological and anatomopathological features of subependymoma are discussed...
  85. ncbi Microsurgical anatomy of the superior petrosal venous complex: new classifications and implications for subtemporal transtentorial and retrosigmoid suprameatal approaches
    Necmettin Tanriover
    Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    J Neurosurg 106:1041-50. 2007
    ....
  86. ncbi Operative management of skull base malignancies: choosing the appropriate approach
    Daniel R Pieper
    Michigan Institute of Cerebrovascular and Skull Base Surgery, Southfield, Michigan, USA
    Neurosurg Focus 12:e6. 2002
    ..Finally, the use of a multidisciplinary team both in and out of the operating room is recommended, emphasizing a team approach during the resection itself...
  87. ncbi Moving toward the petroclival region: a model for quantitative and anatomical analysis of tumor shift
    Sam Safavi-Abbasi
    Neurosurgery Research Laboratory, Division of Neurological Surgery, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona, USA
    J Neurosurg 107:797-804. 2007
    ..quantitatively assessed the effects of balloon inflation as a model of tumor compression on the brainstem, cranial nerves, and clivus by measuring the working area, angle of attack, and brain shift associated with the retrosigmoid ..
  88. ncbi Focal enhancement of cranial nerve V after radiosurgery with the Leksell gamma knife: experience in 15 patients with medically refractory trigeminal neuralgia
    R A Alberico
    Departments of Diagnostic Radiology (R.A.A.) and Neurosurgery (R.A.F, Roswell Park Cancer Institute, Buffalo, NY
    AJNR Am J Neuroradiol 22:1944-8. 2001
    ..Lack of trigeminal nerve enhancement occurred only with lower doses (35 Gy at 50%). MR imaging may be useful to confirm the presence and location of the treatment site after gamma knife radiosurgery for trigeminal neuralgia...
  89. ncbi Prevention and treatment of postoperative nausea and vomiting
    A L Kovac
    Department of Anaesthesiology, University of Kansas Medical Center, Kansas City 66160 7415, USA
    Drugs 59:213-43. 2000
    ..muscarinic, cholinergic, opioid, histamine, serotonin (5-hydroxy-tryptamine; 5-HT)] and physiology [cranial nerves VIII (acoustic-vestibular), IX (glossopharyngeal) and X (vagus), gastrointestinal reflex] relating to PONV are ..
  90. ncbi [Recovery of facial nerve function using sural nerve transplantation after its injury in acoustic nerve surgery]
    E Nemeth
    Sluzba za fizikalnu medicinu i rehabilitaciju, Zdravstveni centar Dr Gere Istvan, Senta
    Med Pregl 52:283-6. 1999
    ..its growth the tumor exerts pressure on the surrounding anatomic forms within the pontocerebellar angle: cranial nerves, pons, cerebellum...
  91. ncbi Brain and sense organ anatomy and histology of two species of phyletically basal non-Antarctic thornfishes of the Antarctic suborder Notothenioidei (Perciformes: Bovichtidae)
    Joseph T Eastman
    Department of Biomedical Sciences, College of Osteopathic Medicine, Ohio University, Athens, Ohio 45701 2979, USA
    J Morphol 268:485-503. 2007
    ..We provide detailed drawings of the brains and cranial nerves of both species...
  92. ncbi The tentorial notch: anatomical variation, morphometric analysis, and classification in 100 human autopsy cases
    David E Adler
    Department of Neurosurgery, Legacy Health System, Portland, Oregon, USA
    J Neurosurg 96:1103-12. 2002
    ....
  93. ncbi Treatment for diabetic mononeuropathy with alpha-lipoic acid
    T Tankova
    Clinic of Diabetology, Clinical Centre of Endocrinology, Clinic of Neurology, Medical University, Sofia, Bulgaria
    Int J Clin Pract 59:645-50. 2005
    ..7 +/- 17.4 years; mean duration of diabetes: 13.6 +/- 6.9 years) -- with diabetic mononeuropathy of the cranial nerves participated in the study...
  94. ncbi Surgical approaches: postoperative care and complications "posterolateral-far lateral transcondylar approach to the ventral foramen magnum and upper cervical spinal canal"
    Arnold H Menezes
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 1824 JPP, Iowa City, Iowa 52242, USA
    Childs Nerv Syst 24:1203-7. 2008
    ..The posterolateral transcondylar approach provides such a route. In addition, posterior craniocervical stabilization can be accomplished at the same time. The author has reviewed the technique as well as the surgical results here...
  95. ncbi Fatal grand mal seizure in a Dutch trekker
    B Basnyat
    Medical Director, Himalayan Rescue Association and Nepal International Clinic, Medical Attending, Patan Hospital, Lal Durbar, Kathmandu, Nepal
    J Travel Med 5:221-2. 1998
    ..Her pulse was 70 beats per minute and her BP was 110/80 mm of Hg. Her fundi and cranial nerves exam were completely normal...
  96. ncbi Auditory brainstem implantation: the University of Verona experience
    Vittorio Colletti
    ENT Department, University of Verona, Italy
    Otolaryngol Head Neck Surg 127:84-96. 2002
    ....
  97. ncbi Malignant peripheral nerve sheath tumors of cranial nerves and intracranial contents: a clinicopathologic study of 17 cases
    Bernd W Scheithauer
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 33:325-38. 2009
    Malignant peripheral nerve sheath tumors (MPNSTs) arising from cranial nerves or their branches are very uncommon. The literature consists mainly of isolated case reports and small series...
  98. ncbi Anatomy and histology of the brain and sense organs of the Antarctic eel cod Muraenolepis microps (Gadiformes; Muraenolepididae)
    J T Eastman
    Department of Biomedical Sciences, College of Osteopathic Medicine, Ohio University, Athens, Ohio 45701 2979, USA
    J Morphol 250:34-50. 2001
    Brain regions, cranial nerves, and sense organs in Muraenolepis microps, an Antarctic gadiform fish, were examined to determine which features could be attributed to a gadiform ancestry and which to habitation of Antarctic waters...
  99. ncbi Anatomical study of the trigeminal and facial cranial nerves with the aid of 3.0-tesla magnetic resonance imaging
    Yukinari Kakizawa
    Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan
    J Neurosurg 108:483-90. 2008
    ..They also investigated the correlation between aging and the anatomical measurements of the trigeminal and facial nerves...
  100. ncbi The fictively breathing tadpole brainstem preparation as a model for the development of respiratory pattern generation and central chemoreception
    M J Gdovin
    Division of Life Sciences, University of Texas at San Antonio 78249, USA
    Comp Biochem Physiol A Mol Integr Physiol 124:275-86. 1999
    ..Characterization of gill and lung ventilatory activity in cranial nerves in the spontaneously breathing tadpole Rana catesbeiana, FASEB J 1996;10(3):A642; Gdovin MJ, Torgerson CS, ..
  101. ncbi The locked-in syndrome: a syndrome looking for a therapy
    Jose Leon-Carrion
    University of Seville, Spain
    Brain Inj 16:571-82. 2002
    ..an obstruction of the basilar artery, and characterized by upper motor neuron quadriplegia, paralysis of lower cranial nerves, bilateral paresis of horizontal gaze and anarthria, and with preserved consciousness...

Research Grants62

  1. Human in Mouse Modeling of HNSCC to Predict Resonse to Therapy
    Wendell G Yarbrough; Fiscal Year: 2010
    ..role of structures of the upper aerodigestive tract in speech and swallowing and due to the concentration of cranial nerves and major blood vessels in the neck, standard therapeutic modalities frequently result in unacceptable ..
  2. Genetic Regulation of Rhombomere Formation
    CHARLES G SAGERSTROM; Fiscal Year: 2013
    ..g. reticulospinal interneurons and motornuclei of the cranial nerves) and is therefore essential for normal neurological activity...
  3. Prediction of Physiological Events in People with Sleep Disordered Breathing
    Jonathan A Waxman; Fiscal Year: 2011
    ..Other therapies, such as the electrical stimulation of various cranial nerves or pharyngeal muscles, could also be improved by predicting disordered breathing...
  4. Fibulin-1 Regulation of the DiGeorge Syndrome Pathogenesis Pathway
    WILLIAM SCOTT ARGRAVES; Fiscal Year: 2012
    ..fibulin-1 (Fbln1) is required for normal development of the cardiac outflow tract (OFT), pharyngeal glands, cranial nerves and bones of the skull...
  5. Molecular Imaging of Retrograde Nerve Transport
    DAWID NONE SCHELLINGERHOUT; Fiscal Year: 2013
    ..In this application we hope to: 1-extend our experience to other anatomic sites, specifically the cranial nerves where crippling nerve disease frequently occurs, 2-develop new variants of our agent to improve our imaging ..
  6. Netrin5 in Mammalian Neurodevelopment
    Robert W Burgess; Fiscal Year: 2013
    ..The development of motor and sensory neurons in the spinal cord and cranial nerves is well studied;however, major questions remain, including how motor axons identify the ventral motor exit ..
  7. STRUCTURAL BASIS OF AMBLYOPIA AND STRABISMUS
    Jonathan C Horton; Fiscal Year: 2012
    ..The crucial point is that the ocular misalignment usually occurs without any abnormality of the cranial nerves or intrinsic disorder of the eyes...
  8. Sensorimotor control of the oropharynx and esophagus
    RODERICK ATKINS SUTHERS; Fiscal Year: 2013
    ..specific aim will use neuroanatomical and neurophysiological techniques to map the premotor pathways of the cranial nerves in order to identify the neural pathways by which auditory information accesses the motoneurons to muscles of ..
  9. NEURAL REGULATION OF VASOPRESSIN RELEASE
    J Thomas Cunningham; Fiscal Year: 2010
    ..The inhibition of vasopressin release by water intake involves oropharyngeal afferents from the IXth and Xth cranial nerves but not gustatory afferents of the Vllth cranial nerve. 2...
  10. 2010 Conference on neurofibromatosis type 2.
    Marco Giovannini; Fiscal Year: 2010
    ..disorder associated primarily with bilateral schwannomas seen on the superior vestibular branches of the 8th cranial nerves. Significant morbidity, including deafness, can result from surgical treatment of these tumors...
  11. Tissue interactions in taste bud development
    Linda A Barlow; Fiscal Year: 2013
    ..by applicant): Taste buds are found in a distributed array on the tongue surface, and are innervated by cranial nerves that convey taste information to the brain...
  12. Neurological Exams Teaching &Evaluation Using Virtual Patients
    Benjamin Lok; Fiscal Year: 2013
    ..b>Cranial nerves palsies are nerve disorders that can result in patients that present asymmetric eye movement or facial ..
  13. Immersive Virtual Patients with Abnormal Clinical Conditions for Medical Student
    Benjamin Lok; Fiscal Year: 2009
    ..The blurred vision will be caused by one of the following: 1) An injury to one of the cranial nerves, 2) diabetic retinal disease, or 3) cranial mass (brain tumor)...
  14. Oral Sensation During Pharyngeal Swallowing in Infant Mammals
    Shaina Devi Holman; Fiscal Year: 2012
    ..applicant): Swallowing is a well-coordinated activity regulated by the hyolaryngeal muscles and at least five cranial nerves. Swallowing disorders, or dysphagia, can impact nutrition and quality of life for infants...
  15. Scientific Conference on Moebius Syndrome
    VICKI MCCARRELL; Fiscal Year: 2006
    ..a rare, congenital (present from birth) disorder defined by the partial or complete absence of the 6th and 7th cranial nerves, which control eye movements and facial expression...
  16. SALIVARY GLANDS AND THEIR INNERVATION IN DIABETES
    JACOB HANKER; Fiscal Year: 1980
    ..by acetylcholinesterase-positive parasympathetic fibers from branches of the fifth, seventh, ninth and tenth cranial nerves, will be assessed by examining the fibers with a precise histochemical method for acetylcholinesterase...
  17. Embryonic development of taste buds.
    LINDA BARLOW; Fiscal Year: 2009
    Taste buds are multicellular receptor organs of the gustatory system, and are innervated by a discrete set of cranial nerves. For nearly a century, taste buds were believed to form late in embryonic development following induction by ..
  18. Intertrigeminal region control of apnea
    Miodrag Radulovacki; Fiscal Year: 2007
    ..The ITR is innervated by sensory subnuclei of the solitary tract that receive inputs from the ninth and tenth cranial nerves; each of which mediate airway-protective apneic reflexes...
  19. Development of Avian Extraocular Muscles and Nerves
    Drew Noden; Fiscal Year: 2007
    ..b>Cranial nerves In, IV, and VI arise in separate locations and each shows patterns of early outgrowth that are unique...
  20. THE DEVELOPMENT OF THE EYE AND ITS ADNEXA
    ANTHONY PEARSON; Fiscal Year: 1980
    ..The emphasis will be on the development of the eye and the cranial nerves related to it, the orbit and its contents, the eyelids, and the lacrimal apparatus...
  21. F MRI STUDY OF TASTE CORTEX USING FOCAL STIMULI
    Michael Barry; Fiscal Year: 2001
    ..of the human taste system includes 5 distinct fields of taste buds, innervated by at least 4 branches of 3 cranial nerves. Thus loss of taste function resulting from peripheral lesions or disease is rarely complete...
  22. FGF SIGNALING DURING CRANIAL PLACODE DEVELOPMENT
    Alex Nechiporuk; Fiscal Year: 2006
    ..The proper development of cranial nerves is essential for the formation of cranial sensory systems such as vision, smell, hearing, somatosensation, and ..
  23. DEVELOPMENT OF THE GUSTATORY SYSTEM
    RICHARD NORTHCUTT; Fiscal Year: 2005
    ..To test the hypothesis that retinoic acid acts as a signal to pattern endoderm directly during gastrulation (aim 3), presumptive pharyngeal endoderm will be excised, exposed to retinoic acid, and cultured. ..
  24. DEVELOPMENT OF THE OLFACTORY SYSTEM IN ZEBRAFISH
    KATHLEEN WHITLOCK; Fiscal Year: 2004
    ..abstract_text> ..
  25. Development of gonadotropin releasing hormone cells
    KATHLEEN WHITLOCK; Fiscal Year: 2009
    ....
  26. Ethanol, neurotrophins, and thalamocortical matching
    SANDRA MOONEY; Fiscal Year: 2006
    ..abstract_text> ..
  27. Trigeminal Neuralgia Association 5th National Conference
    Albert Rhoton; Fiscal Year: 2005
    ..abstract_text> ..
  28. Mechanisms of prion transport
    RICHARD BESSEN; Fiscal Year: 2008
    ..These studies can determine the role of the olfactory nerve in centrifugal prion spread to the nasal mucosa where agent shedding is a potential route of prion transmission. ..
  29. Genetic analysis of hair cell regeneration in zebrafish
    David Raible; Fiscal Year: 2008
    ..In contrast, hair cells regenerate in other animals. Understanding the regulatory mechanisms behind successful regeneration will influence strategies towards recovery of function in humans. [unreadable] [unreadable]..
  30. Insular AD Pathology and Autonomic Function
    Donald Royall; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  31. Development of Cranial Motor Neurons
    Anand Chandrasekhar; Fiscal Year: 2007
    ..Together, these experiments will generate novel insight into neuronal migration mechanisms in the vertebrate hindbrain. ..
  32. NURR1 EXPRESSION AND DAERGIC DYSFUNCTION RELEVANT TO PD
    Wei Dong LE; Fiscal Year: 2003
    ....
  33. Presynaptic Mechanisms of Neurotransmission in NTS
    MICHAEL ANDRESEN; Fiscal Year: 2009
    ..The different sub classes of afferent nerve terminal will be also be compared in terms of their control of glutamate release and modulation by peptides. ..
  34. Wearable-Sensor System for Monitoring Motor Function
    Carlo J De Luca; Fiscal Year: 2010
    ..The successful development of this technology will be transferred for commercial development with the financial assistance of the Massachusetts Community Technology Foundation. ..
  35. Methylphenidate & gene expression in the rat brain.
    JOAN BAIZER; Fiscal Year: 2004
    ..abstract_text> ..
  36. Herpesviruses in Vestibular Neuritis
    JEFFREY VRABEC; Fiscal Year: 2003
    ..This information can help determine why some individuals with latent virus in the vestibular ganglion develop clinical symptoms due to reactivation and some do not. ..
  37. NURR1 Gene Mutations in Parkinson's Disease
    Weidong Le; Fiscal Year: 2006
    ....
  38. Dyspraxia and Autonomic Control in Very Early AD
    Donald Royall; Fiscal Year: 2004
    ..Some dementia treatments are known to reduce HRV, and possibly mortality as well. Alternatively, some psychotropics may increase arrhythmia-related mortality, possibly via a central mechanism. ..
  39. HARNESSING MOTONEURON ACTIVITY: FROM LAB TO CLINIC
    Carlo De Luca; Fiscal Year: 2004
    ..As well as testing specific hypotheses, these studies will be used to test and improve the evolving design of the new decomposition system. ..
  40. The Role of BDNF in Gustatory Neuron Development
    DANIELLE HARLOW; Fiscal Year: 2007
    ..My results will lend basic insight into events of normal vertebrate embryogenesis and provide elementary data for the study of neurological defects. [unreadable] [unreadable] [unreadable]..
  41. IMPROVED CELL COUNTING USING THE OPTICAL DISECTOR
    CHRISTOPHER VON BARTHELD; Fiscal Year: 2004
    ....
  42. NEURONAL PATHWAYS UNDERLYING IN VITRO MOTOR LEARNING
    Joyce Keifer; Fiscal Year: 2003
    ....
  43. REGULATION OF NEURAL CREST DEVELOPMENT
    David Raible; Fiscal Year: 2003
    ..He will test whether BMP2 plays a role in distinguishing between neural crest and placode. ..
  44. Role of BDNF in development and maintenance of taste bu*
    LINDA BARLOW; Fiscal Year: 2002
    ..For these experiments the epibranchial placodes, which give rise to the gustatory ganglia of the VII and IX cranial nerves, will be cultured with appropriate and inappropriate epithelium taken from early embryos; i.e...
  45. CRANIOFACIAL DEVELOPMENT
    GURKIRPAL SOHAL; Fiscal Year: 2001
    ..Results of this study likely will alter our interpretations of mechanisms of normal development, and of the underlying causes of craniofacial anomalies, which make up about 25 percent of all malformations. ..
  46. NEUROETHOLOGY OF VOCAL COMMUNICATION
    Andrea Simmons; Fiscal Year: 2006
    ..abstract_text> ..
  47. Non-Invasive System for Identifying Neural Behavior
    Carlo De Luca; Fiscal Year: 2009
    ..It will be useful to clinicians for assessing the degree of dysfunction in upper motoneuron diseases such as Cerebral Palsy, Parkinson's Disease, ALS, Stroke, and other disorders. ..
  48. Posttranslational Regulation of eNOS by Estrogen in the Vagina and Clitoris
    Biljana Musicki; Fiscal Year: 2007
    ..At the same time it may advance treatments for multiple disease states associated with endothelial dysfunction and alterations in hormonal milieu. [unreadable] [unreadable] [unreadable]..
  49. Personal Electrocardiographic Expert System
    Vladimir Shusterman; Fiscal Year: 2007
    ..Safety and regulatory testing will be completed, and a 51O K application will be submitted to the FDA. [unreadable] [unreadable]..
  50. CENTRAL BAROREFLEX MECHANISMS OF ANESTHETIC ACTION
    MICHAEL ANDRESEN; Fiscal Year: 2006
    ..By examining different anesthetics, we may also better understand whether potentially new anesthetics might be designed to spare these cardioregulatory sites. [unreadable] [unreadable]..
  51. Surgical Management of Facial Nerve Injury
    Theresa Hadlock; Fiscal Year: 2007
    ..The academic environment is one of complete dedication to advancing both biomedical science and patient care through careful study and diligent investigation, and of support for the mentored investigator. [unreadable] [unreadable]..
  52. eNOS-Protein Interaction in the Penis
    Biljana Musicki; Fiscal Year: 2007
    ..At the same time, it may suggest a specific eNOS regulatory pathway as a possible new molecular target for treating ED. [unreadable] [unreadable] [unreadable]..
  53. PEDIATRICS AIDS CLINICAL TRIALS GROUP
    Anne Gershon; Fiscal Year: 2006
    ..We have competent, outstanding staff whose aim is not only to provide compassionate medical care to HIV-infected patients but also to perform meaningful and useful research on prevention and treatment of HIV infection. ..
  54. VAS-COG 2007
    Donald Royall; Fiscal Year: 2007
    ..Many vascular cognitive disorders are preventable and potentially reversible. VAS-COG will provide a forum in which information on these important conditions can be exchanged and disseminated. [unreadable] [unreadable] [unreadable]..
  55. MECHANISMS AND SITES OF VENTILATORY NEUROGENESIS
    WALTER ST JOHN; Fiscal Year: 2008
    ..Such information might provide insights into dysfunctions of the control of ventilation in humans, such as in "sleep apnea" or the "sudden infant death syndrome." [unreadable] [unreadable] [unreadable]..
  56. Replacing an Animal Resource Facility Cage Washer.
    Kristen Drescher; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  57. Cell Fate Regulation by Transcriptional Repression
    David Raible; Fiscal Year: 2006
    ..These experiments will shed light on the differentiation of a possible common glial/melanoblast precursor and lead to understanding how abnormal development of this precursor might underlie congenital tumors. ..
  58. Transmission Across the First Synapse of the Baroreflex
    MICHAEL ANDRESEN; Fiscal Year: 2009
    ..These Aims will provide new and direct information about NTS that leads to a better understanding of the normal basis of the neural control of the circulation as pathophysiology. ..
  59. VZV Receptors and Infective Mechanisms
    Anne Gershon; Fiscal Year: 2007
    ..It may also make it possible to develop a safer and more efficacious vaccine. ..
  60. GENETIC MECHANISMS OF HINDBRAIN SEGMENTATION
    Cecilia Moens; Fiscal Year: 2009
    ..Aim 2 addresses the mechanism of plasticity. Finally, in Aim 3, we consider the mechanism by which long-range signals interact to specify the positions of specific hindbrain boundaries. ..
  61. Contributions of VENT cells to the GI tract
    GURKIRPAL SOHAL; Fiscal Year: 2007
    ..RESEARCH GRANT TABLE OF CONTENTS Page Numbers Face Page .................................................................................................................................................. 1 Description, ..
  62. NEURAL MECHANISMS OF ADAPTIVE BEHAVIOR
    Joyce Keifer; Fiscal Year: 2009
    ..For research focused on the changes to neural function induced by chronic social stress during adolescence, and to direct pharmacotherapy of associated psychiatric disorders. ..