parasympathetic nervous system

Summary

Summary: The craniosacral division of the autonomic nervous system. The cell bodies of the parasympathetic preganglionic fibers are in brain stem nuclei and in the sacral spinal cord. They synapse in cranial autonomic ganglia or in terminal ganglia near target organs. The parasympathetic nervous system generally acts to conserve resources and restore homeostasis, often with effects reciprocal to the sympathetic nervous system.

Top Publications

  1. ncbi Autonomic changes during wake-sleep transition: a heart rate variability based approach
    Zvi Shinar
    Abramson Center for Medical Physics, Tel Aviv University, Tel Aviv, Israel
    Auton Neurosci 130:17-27. 2006
  2. ncbi Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFR alpha2, a functional neurturin receptor
    J Rossi
    Program of Molecular Neurobiology, Institute of Biotechnology, University of Helsinki, Finland
    Neuron 22:243-52. 1999
  3. ncbi Relationship of heart rate variability to parasympathetic effect
    J J Goldberger
    Division of Cardiology, Department of Medicine, Northwestern University, Chicago, Illinois, USA
    Circulation 103:1977-83. 2001
  4. ncbi Effect of cold water immersion on postexercise parasympathetic reactivation
    M Buchheit
    Research Laboratory, EA 3300 Exercise Physiology and Rehabilitation, Faculty of Sports Sciences, University of Picardie, Jules Verne, Amiens, France
    Am J Physiol Heart Circ Physiol 296:H421-7. 2009
  5. ncbi GDNF and neurturin are target-derived factors essential for cranial parasympathetic neuron development
    E Hashino
    Center for Hearing and Deafness, State University of New York at Buffalo, Buffalo, NY 14214, USA
    Development 128:3773-82. 2001
  6. ncbi Influence of cold water face immersion on post-exercise parasympathetic reactivation
    Hani Al Haddad
    Faculty of Sport Sciences, University of Picardie, Amiens, France
    Eur J Appl Physiol 108:599-606. 2010
  7. ncbi Noninvasive assessment of cardiac parasympathetic function: postexercise heart rate recovery or heart rate variability?
    Martin Buchheit
    Am J Physiol Heart Circ Physiol 293:H8-10. 2007
  8. ncbi GDNF family signalling in exocrine tissues: distinct roles for GDNF and neurturin in parasympathetic neuron development
    Jari Rossi
    Program in Molecular Neurobiology, Institute of Biotechnology, Viikki Biocenter, University of Helsinki, Finland
    Adv Exp Med Biol 506:19-26. 2002
  9. ncbi Spatial segregation within the sacral parasympathetic nucleus of neurons innervating the bladder or the penis of the rat as revealed by three-dimensional reconstruction
    B Banrezes
    Analyse et Modélisation en Imagerie Biologique, I N R A Jeune Equipe 1060 77, 78352 Jouy en Josas, France
    Neuroscience 115:97-109. 2002
  10. ncbi Gene targeting reveals a critical role for neurturin in the development and maintenance of enteric, sensory, and parasympathetic neurons
    R O Heuckeroth
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 22:253-63. 1999

Detail Information

Publications239 found, 100 shown here

  1. ncbi Autonomic changes during wake-sleep transition: a heart rate variability based approach
    Zvi Shinar
    Abramson Center for Medical Physics, Tel Aviv University, Tel Aviv, Israel
    Auton Neurosci 130:17-27. 2006
    ....
  2. ncbi Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFR alpha2, a functional neurturin receptor
    J Rossi
    Program of Molecular Neurobiology, Institute of Biotechnology, University of Helsinki, Finland
    Neuron 22:243-52. 1999
    ..Thus, GFR alpha2 is a physiological NTN receptor, essential for the development of specific postganglionic parasympathetic neurons...
  3. ncbi Relationship of heart rate variability to parasympathetic effect
    J J Goldberger
    Division of Cardiology, Department of Medicine, Northwestern University, Chicago, Illinois, USA
    Circulation 103:1977-83. 2001
    ..We postulated that a quadratic function would describe the relationship between HRV and parasympathetic effect better than a linear function...
  4. ncbi Effect of cold water immersion on postexercise parasympathetic reactivation
    M Buchheit
    Research Laboratory, EA 3300 Exercise Physiology and Rehabilitation, Faculty of Sports Sciences, University of Picardie, Jules Verne, Amiens, France
    Am J Physiol Heart Circ Physiol 296:H421-7. 2009
    ..CWI may serve as a simple and effective means to accelerate parasympathetic reactivation during the immediate period following supramaximal exercise...
  5. ncbi GDNF and neurturin are target-derived factors essential for cranial parasympathetic neuron development
    E Hashino
    Center for Hearing and Deafness, State University of New York at Buffalo, Buffalo, NY 14214, USA
    Development 128:3773-82. 2001
    ....
  6. ncbi Influence of cold water face immersion on post-exercise parasympathetic reactivation
    Hani Al Haddad
    Faculty of Sport Sciences, University of Picardie, Amiens, France
    Eur J Appl Physiol 108:599-606. 2010
    ..026) and HRR (P = 0.002) values for the CWFI compared with the CON condition. Cold water face immersion appears to be a simple and efficient means of immediately accelerating post-exercise parasympathetic reactivation...
  7. ncbi Noninvasive assessment of cardiac parasympathetic function: postexercise heart rate recovery or heart rate variability?
    Martin Buchheit
    Am J Physiol Heart Circ Physiol 293:H8-10. 2007
  8. ncbi GDNF family signalling in exocrine tissues: distinct roles for GDNF and neurturin in parasympathetic neuron development
    Jari Rossi
    Program in Molecular Neurobiology, Institute of Biotechnology, Viikki Biocenter, University of Helsinki, Finland
    Adv Exp Med Biol 506:19-26. 2002
  9. ncbi Spatial segregation within the sacral parasympathetic nucleus of neurons innervating the bladder or the penis of the rat as revealed by three-dimensional reconstruction
    B Banrezes
    Analyse et Modélisation en Imagerie Biologique, I N R A Jeune Equipe 1060 77, 78352 Jouy en Josas, France
    Neuroscience 115:97-109. 2002
    ..These results support the hypothesis of a viscerotopic organization of sacral neurons providing the spinal control of pelvic organs...
  10. ncbi Gene targeting reveals a critical role for neurturin in the development and maintenance of enteric, sensory, and parasympathetic neurons
    R O Heuckeroth
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 22:253-63. 1999
    ..The loss of GFR alpha2-expressing neurons, in conjunction with earlier studies, provides strong support for GFR alpha2/Ret receptor complexes as the critical mediators of NTN function in vivo...
  11. doi Parasympathetic nervous system and heart failure: pathophysiology and potential implications for therapy
    Brian Olshansky
    Division of Cardiology, University of Iowa Hospitals, 200 Hawkins Dr 4426a JCP, Iowa City, IA 52242, USA
    Circulation 118:863-71. 2008
  12. ncbi Muscarinic acetylcholine receptors and airway diseases
    Fiona R Coulson
    Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Pharmacol Ther 98:59-69. 2003
    ..The mechanisms by which neuronal M(2) muscarinic receptor function is lost and its relevance to human airway disease are discussed in this review...
  13. ncbi Parasympathetic innervation and function of endocrine pancreas requires the glial cell line-derived factor family receptor alpha2 (GFRalpha2)
    Jari Rossi
    Neuroscience Center, P O Box 56 Viikinkaari 4, 00014 University of Helsinki, Finland
    Diabetes 54:1324-30. 2005
    ..The GFRalpha2-KO mouse represents a useful model to study the role of parasympathetic innervation of the endocrine pancreas in glucose homeostasis...
  14. pmc The parasympathetic nervous system in the quest for stroke therapeutics
    Cletus Cheyuo
    Center for Immunology and Inflammation, The Feinstein Institute for Medical Research, Manhasset, NY 11030, USA
    J Cereb Blood Flow Metab 31:1187-95. 2011
    ..Activation of the parasympathetic nervous system (PNS) has been shown to antagonize a multiplicity of pathologic mechanisms...
  15. ncbi Links between adolescent sympathetic and parasympathetic nervous system functioning and interpersonal behavior over time
    Lisa M Diamond
    University of Utah, USA
    Int J Psychophysiol 88:339-48. 2013
    ....
  16. ncbi Mortality, cardiac vagal control and physical training--what's the link?
    Ashesh N Buch
    Department of Cardiovascular Medicine, University of Birmingham, UK
    Exp Physiol 87:423-35. 2002
    ..If the mechanism of increase in cardiac vagal activity with training can be determined it may be possible to use pharmacological approaches to mimic the effects of exercise with potentially beneficial effects...
  17. ncbi Suprachiasmatic GABAergic inputs to the paraventricular nucleus control plasma glucose concentrations in the rat via sympathetic innervation of the liver
    Andries Kalsbeek
    Netherlands Institute for Brain Research, 1105 AZ Amsterdam, The Netherlands
    J Neurosci 24:7604-13. 2004
    ....
  18. ncbi Acetylcholine release in human heart atrium: influence of muscarinic autoreceptors, diabetes, and age
    V Oberhauser
    , Innere Medizin IV, Freiburg, Germany
    Circulation 103:1638-43. 2001
    ..Locally impaired cardiac acetylcholine release may therefore represent a pathophysiological link to sudden cardiac death in elderly and diabetic patients...
  19. ncbi Heart rate variability in athletes: relationship with central and peripheral performance
    R Hedelin
    Sports Medicine and Clinical Physiology, Department of Surgical and Perioperative Science, Umea University, Umea, Sweden
    Med Sci Sports Exerc 33:1394-8. 2001
    ..To investigate relationships between heart rate variability (HRV) and peripheral and central performance measures, 17 cross-country (X-C) skiers and seven canoeists were studied before and after a training period of 7 months...
  20. ncbi Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function
    P Gilon
    Unité d Endocrinologie et Métabolisme, University of Louvain Faculty of Medicine, B 1200 Brussels, Belgium
    Endocr Rev 22:565-604. 2001
    ..The paper also discusses the mechanisms explaining the glucose dependence of the effects of ACh on insulin release...
  21. pmc Somatostatin presynaptically inhibits both GABA and glutamate release onto rat basal forebrain cholinergic neurons
    Toshihiko Momiyama
    Division of Cerebral Structure, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8787, Japan
    J Neurophysiol 96:686-94. 2006
    ..These findings suggest that SS presynaptically inhibits both GABA and glutamate release onto BF cholinergic neurons in a Ca(2+)-dependent way, and that SS-induced effect on IPSCs and EPSCs are mediated by different sst subtypes...
  22. ncbi Eosinophil adhesion to cholinergic nerves via ICAM-1 and VCAM-1 and associated eosinophil degranulation
    Deborah A Sawatzky
    Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool L69 3GE, United Kingdom
    Am J Physiol Lung Cell Mol Physiol 282:L1279-88. 2002
    ..Thus eosinophils adhere to cholinergic nerves via specific adhesion molecules, and this leads to eosinophil activation and degranulation; this may be part of the mechanism of eosinophil-induced vagal hyperreactivity...
  23. pmc Neuronal eotaxin and the effects of CCR3 antagonist on airway hyperreactivity and M2 receptor dysfunction
    Allison D Fryer
    Division of Pulmonary and Critical Care Medicine and Department of Physiology and Pharmacology, Oregon Health and Science University, Portland, Oregon 97201, USA
    J Clin Invest 116:228-36. 2006
    ..Thus, signaling via CCR3 mediates eosinophil recruitment to airway nerves and may be a prerequisite to blockade of inhibitory M2Rs by eosinophil major basic protein...
  24. ncbi Activation of the parasympathetic nervous system is necessary for normal meal-induced insulin secretion in rhesus macaques
    D A D'Alessio
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Clin Endocrinol Metab 86:1253-9. 2001
    ..In addition, the parasympathetic nervous system (PNS) is known to mediate preabsorptive, or cephalic phase, insulin secretion...
  25. ncbi Children with disturbances in sensory processing: a pilot study examining the role of the parasympathetic nervous system
    Roseann C Schaaf
    Department of Occupational Therapy, Thomas Jefferson University, 130 South 9th Street, Edison 810, Philadelphia, Pennsylvania 19107, USA
    Am J Occup Ther 57:442-9. 2003
    This study was a preliminary investigation of parasympathetic nervous system (PNS) functioning in children with disturbances in sensory processing...
  26. ncbi The sympathetic and parasympathetic nature of neuropeptide Y-immunoreactive nerve fibres in the major salivary glands of the rat
    T Schultz
    Department of Anatomy, University of Helsinki, Finland
    Histochem J 26:563-70. 1994
    ..Unilateral electrocoagulation of the trigeminal nerve branches caused no detectable change in the density of immunoreactive nerve fibres in any of the major salivary glands.(ABSTRACT TRUNCATED AT 250 WORDS)..
  27. ncbi Cholinergic control of heart rate by nitric oxide is site specific
    Neil Herring
    University Laboratory of Physiology, Oxford University, Oxford OX1 3PT, UK
    News Physiol Sci 17:202-6. 2002
    ..Endogenous nitric oxide can potentially regulate all of these processes; however, recent work suggests that the main functional role of nitric oxide lies in the modulation of acetylcholine release...
  28. ncbi Neural regulation of blood flow in the rat submandibular gland
    L C Anderson
    Dept Oral Biology, University of Washington, Seattle 98195, USA
    Eur J Morphol 36:213-8. 1998
    ..Parasympathetic vasodilation was due to NO-independent mechanisms mediated by acetylcholine and substance P, and NO-dependent mechanisms mediated by VIP...
  29. pmc Role of SREBP-1 in the development of parasympathetic dysfunction in the hearts of type 1 diabetic Akita mice
    Ho Jin Park
    Tufts Medical Center, Molecular Cardiology Research Institute, 750 Washington St, Box 8486, Boston, MA 02111, USA
    Circ Res 105:287-94. 2009
    ..Sterol regulatory element binding protein-1 (SREBP-1) is a lipid-sensitive transcription factor...
  30. ncbi Moderate pressure massage elicits a parasympathetic nervous system response
    Miguel A Diego
    Touch Research Institute, Department of Pediatrics, University of Miami School of Medicine, Miami, Florida, USA
    Int J Neurosci 119:630-8. 2009
    ..The participants who received the moderate pressure massage exhibited a parasympathetic nervous system response characterized by an increase in HF, suggesting increased vagal efferent activity and a ..
  31. ncbi Parasympathetic and sympathetic control of the pancreas: a role for the suprachiasmatic nucleus and other hypothalamic centers that are involved in the regulation of food intake
    R M Buijs
    Netherlands Institute for Brain Research, Meibergdreef 33, Amsterdam 1105 AZ, The Netherlands
    J Comp Neurol 431:405-23. 2001
    ..Examples are given of a high level of interaction between the sympathetic and parasympathetic nervous system. Several cell groups project to both branches of the autonomic nervous system, sometimes even the same ..
  32. ncbi Excitatory prejunctional beta 2-adrenoceptor distribution within equine airway cholinergic nerves
    X Y Zhang
    Department of Large Animal Clinical Sciences, Michigan State University, East Lansing 48824 1314, USA
    Respir Physiol 106:81-90. 1996
    ....
  33. pmc Impaired neurotransmitter release from lacrimal and salivary gland nerves of a murine model of Sjögren's syndrome
    D Zoukhri
    Schepens Eye Research Institute, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 42:925-32. 2001
    ..The second purpose was to determine whether activation of the lacrimal gland nerves of the MRL/lpr mouse leads to protein secretion...
  34. ncbi Muscarinic receptors and salivary secretion
    Gordon B Proctor
    J Appl Physiol 100:1103-4. 2006
  35. ncbi Heart rate variability under resting conditions in postmenopausal and young women
    T F Ribeiro
    , Departamento de Fisioterapia, , , SP, Brasil
    Braz J Med Biol Res 34:871-7. 2001
    ..Thus, time domain HRV proved to be a noninvasive and sensitive method for the identification of changes in autonomic modulation of the sinus node in postmenopausal women...
  36. pmc Dual innervation of white adipose tissue: some evidence for parasympathetic nervous system involvement
    Timothy J Bartness
    Neurobiology and Behavior Program, Department of Biology and Center for Behavioral Neuroscience, Georgia State University, Atlanta, Georgia 30303 3088, USA
    J Clin Invest 110:1235-7. 2002
  37. ncbi Subtle involvement of the parasympathetic nervous system in patients with irritable bowel syndrome
    Narender P van Orshoven
    Rudolf Magnus Institute of Neuroscience, Dept of Clinical Neurophysiology, University Medical Centre Utrecht, 3508 GA Utrecht, The Netherlands
    Clin Auton Res 16:33-9. 2006
    ..These results suggest that reduced baseline activity as well as responsiveness of the parasympathetic system could play a role in the pathogenesis of IBS...
  38. ncbi Low birth weight is associated with increased sympathetic activity: dependence on genetic factors
    Richard G Ijzerman
    Department of Internal Medicine and Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Circulation 108:566-71. 2003
    ....
  39. ncbi Autonomic effects on QT-RR interval dynamics after exercise
    Sri Sundaram
    Division of Cardiac Electrophysiology, Northwestern University Feinberg School of Medicine, 251 E Huron, Chicago, IL 60611, USA
    Am J Physiol Heart Circ Physiol 294:H490-7. 2008
    ..These data support the concept that parasympathetic tone may provide a natural antiarrhythmic effect during this time...
  40. ncbi Autonomic nervous system response to epidural analgesia in laboring patients by wavelet transform of heart rate and blood pressure variability
    Alain Deschamps
    Department of Anesthesiology, McGill University Health Centre, Royal Victoria Hospital, Quebec, Canada
    Anesthesiology 101:21-7. 2004
    ..The goal of this study was to find markers describing the changes in autonomic nervous system activity with epidural anesthesia in laboring patients...
  41. ncbi Selective quantification of the cardiac sympathetic and parasympathetic nervous systems by multisignal analysis of cardiorespiratory variability
    Xiaoxiao Chen
    Department of Electrical and Computer Engineering, Michigan State University, East Lansing, MI 48824, USA
    Am J Physiol Heart Circ Physiol 294:H362-71. 2008
    ..offer an effective marker of the beta-sympathetic nervous system (SNS) due to its overlap with the parasympathetic nervous system (PNS) in the low-frequency (LF) band nor afford specific measures of the CANS due to input ..
  42. ncbi Control of heart rate variability by cardiac parasympathetic nerve activity during voluntary static exercise in humans with tetraplegia
    Makoto Takahashi
    Dept of Sports Medicine, Graduate School of Health Sciences, Hiroshima University, Minami Ku, Hiroshima 734 8551, Japan
    J Appl Physiol (1985) 103:1669-77. 2007
    ....
  43. ncbi Changes in cardiovascular parameters and plasma norepinephrine level in rats after chronic constriction injury on the sciatic nerve
    Yu Jin
    Futuristic Environmental Simulation Center, Research Institute of Environmental Medicine, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8601, Japan
    Pain 135:221-31. 2008
    ..These results demonstrated that cardiovascular function was kept high through sympathetic and non-sympathetic activity for 2 weeks after CCI, followed by a predominance of parasympathetic tone...
  44. ncbi Effect of dimenhydrinate on autonomic activity in humans
    Jason R Carter
    Dept of Exercise Science, Health and Physical Education, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA
    Clin Auton Res 17:186-92. 2007
    ..01). These results indicate that dimenhydrinate augments heart rate responses to baroreceptor unloading, but does not alter resting MSNA, the sympathetic baroreflexes, or the vestibulosympathetic reflex...
  45. ncbi Increased sympathetic and decreased parasympathetic cardiovascular modulation in normal humans with acute sleep deprivation
    Xu Zhong
    Division of Pulmonary, Allergy and Critical Care, Columbia University College of Physicians and Surgeons, 622 West 168th Street, VC 12 206, New York, NY 10032, USA
    J Appl Physiol 98:2024-32. 2005
    ..In summary, acute SD was associated with increased sympathetic and decreased parasympathetic cardiovascular modulation and decreased BRS, most consistently in the seated position and during simple reaction-time testing...
  46. ncbi Heart rate variability and the exercise pressor reflex during dynamic handgrip exercise and postexercise arterial occlusion
    Heidi A Kluess
    Department of Kinesiology, Louisiana State University, Baton Rouge, Louisiana 70803, USA
    Am J Med Sci 329:117-23. 2005
    ..The purpose was to describe the exercise pressor reflex by observing heart rate variability and blood pressure responses to handgrip-exercise and postexercise arterial occlusion...
  47. ncbi Basic autonomic nervous function in patients with neurocardiogenic syncope
    Fumio Saito
    Department of Cardiology, Surugadai Nihon University Hospital, Tokyo, Japan
    Clin Exp Hypertens 29:165-73. 2007
    ....
  48. pmc Heart rate variability and short duration spaceflight: relationship to post-flight orthostatic intolerance
    Andrew P Blaber
    School of Kinesiology, Simon Fraser University, Burnaby, BC, Canada N6A 3K7
    BMC Physiol 4:6. 2004
    ....
  49. ncbi Autonomic nervous system activity in premature and full-term infants from theoretical term to 7 years
    Ivan de Rogalski Landrot
    Laboratoire de Physiologie Clinique et de l Exercice The Synapse Research Group, France
    Auton Neurosci 136:105-9. 2007
    ..Furthermore, compared evolution shows a faster ANS maturation in premature. Potential mechanisms are discussed...
  50. ncbi Type 5 adenylyl cyclase disruption alters not only sympathetic but also parasympathetic and calcium-mediated cardiac regulation
    Satoshi Okumura
    Cardiovascular Research Institute, Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, NJ 07101 1709, USA
    Circ Res 93:364-71. 2003
    ....
  51. ncbi Effect of autonomic blockade on ventricular repolarization shortening: response to behavioral stimulus in paced dogs
    Emily R Nolan
    Cardiovascular Research Lab, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, United States
    Auton Neurosci 140:66-71. 2008
    ..The use of a model that eliminates the need to apply correction factors to repolarization indices helps to clarify the role of the autonomic nervous system on ventricular repolarization...
  52. ncbi Parasympathetic cardiac effects in sympathectomized rats
    A R Gizzatullin
    Department of Anatomy, Physiology, and Human Health Protection, Tatar State Humanitarian Pedagogical University, Kazan
    Bull Exp Biol Med 144:166-70. 2007
    ..The sympathetic nervous system plays a role in postvagotomic tachycardia. Sympathectomized rats were characterized by higher reactivity of cardiac beta-adrenoceptors to propranolol compared to intact animals...
  53. pmc Asymmetry in sympathetic and vagal activities during sleep-wake transitions
    Terry B J Kuo
    Institute of Brain Science, National Yang Ming University, Taipei, Taiwan
    Sleep 31:311-20. 2008
    ..To explore the role of autonomic nervous system in initiation of sleep-wake transitions...
  54. ncbi The influence of sleep onset on the diurnal variation in cardiac activity and cardiac control
    Melinda Carrington
    Department of Psychology, University of Melbourne, Parkville, Vic, Australia
    J Sleep Res 12:213-21. 2003
    ....
  55. ncbi Cardiac autonomic activity in methylmercury neurotoxicity: 14-year follow-up of a Faroese birth cohort
    Philippe Grandjean
    Institute of Public Health, University of Southern Denmark, Odense, Denmark
    J Pediatr 144:169-76. 2004
    ..To determine whether heart function in childhood is affected by exposure to methylmercury (MeHg) from seafood...
  56. ncbi Nonlinear analysis of the separate contributions of autonomic nervous systems to heart rate variability using principal dynamic modes
    Yuru Zhong
    Department of Biomedical Engineering, State University of New York at Stony Brook, Stony Brook, NY 11794 8181, USA
    IEEE Trans Biomed Eng 51:255-62. 2004
    ..Our nonlinear PDM approach allows a clear separation of the two autonomic nervous activities, the lack of which has been the main reason why heart rate variability analysis has not had wide clinical acceptance...
  57. ncbi Sympathetic skin response and RR interval variation in patients with cardiac syndrome X
    Armagan Altun
    Cardiology, Medical School, Trakya University, Edirne, Turkey
    Angiology 58:747-50. 2007
    ..variation (RRIV) are noninvasive electrophysiological tests used in the assessment of sympathetic and parasympathetic nervous system function, respectively...
  58. ncbi Effects of vagus nerve stimulation on cardiovascular regulation in patients with epilepsy
    B Stemper
    Department of Neurology, University of Erlangen Nurnberg, Erlangen, Germany
    Acta Neurol Scand 117:231-6. 2008
    ..To evaluate the impact of vagus nerve stimulation (VNS) on heart rate and blood pressure (BP) modulation in epilepsy patients...
  59. ncbi Association of C825T polymorphism of G protein beta3 subunit with the autonomic nervous system in young healthy Japanese individuals
    Tetsuro Matsunaga
    Laboratory of Metabolism, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan
    Am J Hypertens 18:523-9. 2005
    ..In the present study, we have investigated the association of this polymorphism with ANS in young, healthy Japanese male individuals...
  60. pmc Influence of acute progressive hypoxia on cardiovascular variability in conscious spontaneously hypertensive rats
    Mitsutaka Sugimura
    Department of Dental Anesthesiology, Graduate School of Dentistry, Osaka University, 1 8 Yamadaoka, Suita, Osaka 565 0871, Japan
    Auton Neurosci 141:94-103. 2008
    ..Furthermore, it is thought that the influence of acute progressive hypoxia on striatal DA levels is similar in SHR and WKY...
  61. ncbi Abnormal heart rate and blood pressure responses to baroreflex stimulation in multiple sclerosis patients
    Emmanuel O Sanya
    Autonomic Laboratory, Dept of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Clin Auton Res 15:213-8. 2005
    ..27+/-0.29 ln ms(2)). These results indicate that in MS patients, baroreflex dysfunction is not only restricted to the cardiovagal limb of the baroreflex, but that the sympathetic modulation of the blood vessels is also affected...
  62. ncbi Autonomic cardiac modulation in obstructive sleep apnea: effect of an oral jaw-positioning appliance
    Paolo Coruzzi
    Fondazione Don C Gnocchi ONLUS, Fondazione Don C Gnocchi, Piazzale dei Servi n 3, I 43100, Parma, Italy
    Chest 130:1362-8. 2006
    ..The aim of our study was to investigate the responses of autonomic indexes of neural cardiac control to another type of OSA treatment based on an oral jaw-positioning appliance...
  63. ncbi Model for complex heart rate dynamics in health and diseases
    Kiyoshi Kotani
    Graduate School of Information Science and Technology, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8656, Japan
    Phys Rev E Stat Nonlin Soft Matter Phys 72:041904. 2005
    ....
  64. ncbi The many metrics of cardiac chronotropy: a pragmatic primer and a brief comparison of metrics
    John J B Allen
    Department of Psychology, University of Arizona, Tucson, AZ 85721 0068, USA
    Biol Psychol 74:243-62. 2007
    ..Although generally highly correlated, the various metrics responded differently under challenge...
  65. ncbi Dysautonomia rhinitis: associated otolaryngologic manifestations and characterization based on autonomic function tests
    Mohamed Nasser Elsheikh
    Otolaryngology Department, Faculty of Medicine, Tanta University, Tanta, Egypt
    Acta Otolaryngol 126:1206-12. 2006
    ..The term dysautonomia rhinitis may be used to specify this autonomic-related rhinitis...
  66. ncbi Autonomic cardiovascular responses to heme oxygenase inhibition in conscious rats
    Haruhisa Hirakawa
    Department of Physiology, National Defense Medical College, Saitama, Japan
    Hypertension 48:1124-9. 2006
    ..We conclude that the CO/HO system plays an important role in cardiovascular regulation by modulating sympathetic tone...
  67. ncbi Genetic selection on a behavioural fear trait is associated with changes in heart rate variability in quail
    D Valance
    UMR 6175, Physiologie de la Reproduction et des Comportements, INRA Centre de Tours, Nouzilly, France
    Genes Brain Behav 6:339-46. 2007
    ..Selection on tonic immobility duration thus appears to be associated with changes in the sympathovagal control of the heart, which may influence behavioural responses to stressful situations...
  68. ncbi Role of sympathetic and parasympathetic nervous systems in heart rate regulation in cats
    N N Alipov
    Department of Normal Physiology, Russian State Medical University, Moscow
    Bull Exp Biol Med 140:477-82. 2005
    ....
  69. ncbi Quantifying cardiac sympathetic and parasympathetic nervous activities using principal dynamic modes analysis of heart rate variability
    Yuru Zhong
    Department of Biomedical Engineering, State University of New York at Stony Brook, HSC T18, Rm 030, Stony Brook, NY 11794 8181, USA
    Am J Physiol Heart Circ Physiol 291:H1475-83. 2006
    ..These findings suggest that the PDM shows promise as a noninvasive and quantitative marker of ANS imbalance, which has been shown to be a factor in many cardiac and stress-related diseases...
  70. ncbi Hypnotic trait and specific phobia: EEG and autonomic output during phobic stimulation
    Angelo Gemignani
    Department of Physiology and Biochemistry, G Moruzzi, University of Pisa, Via San Zeno 31, 56127 Pisa, Italy
    Brain Res Bull 69:197-203. 2006
    ..However, the presence of a specific phobia attenuates the effectiveness of hypnotizability as a protective factor against possible stress-related cardiac illness...
  71. ncbi Measurement of autonomic dysregulation in multiple sclerosis
    A Kodounis
    251 General Airforce Hospital of Athens, Aeginition University of Neurology Hospital, 401 General Army Hospital of Athens, Athens, Greece
    Acta Neurol Scand 112:403-8. 2005
    ..Exactly 45.45% of patients exhibited subjective symptoms of autonomic dysfunction and 42.42% of patients had abnormal laboratory tests results...
  72. ncbi Blood pressure and heart rate variability response to noninvasive ventilation in patients with exacerbations of chronic obstructive pulmonary disease
    P Skyba
    Department of Respiratory Medicine and Tuberculosis, L Pasteur Teaching Hospital, Kosice, Slovakia
    Physiol Res 56:527-33. 2007
    ..In conclusion, these findings suggest that NPPV may cause improvements in the neural control of heart rate in patients with acute exacerbations of COPD...
  73. ncbi Sympathetic and parasympathetic activities evaluated by heart-rate variability in head injury of various severities
    Chain Fa Su
    The Division of Neurosurgery, Department of Surgery, Tzu Chi University, Hualien, Taiwan, ROC
    Clin Neurophysiol 116:1273-9. 2005
    ....
  74. ncbi Sex differences in monocyte expression of IL-6: role of autonomic mechanisms
    Mary Frances O'Connor
    Cousins Center for Psychoneuroimmunology, UCLA Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, 300 Medical Plaza, Los Angeles, CA 90095 7076, USA
    Am J Physiol Regul Integr Comp Physiol 293:R145-51. 2007
    ..Interventions that target autonomic mechanisms might constitute new strategies to constrain IL-6 production with impacts on inflammatory disease risk in women...
  75. ncbi Peculiarities of autonomic regulation assessed by variability of hemodynamic parameters in rats with different stress resistance
    T N Kirillina
    State Research Institute of General Pathology and Pathological Physiology, Russian Academy of Medical Sciences, Moscow
    Bull Exp Biol Med 142:398-402. 2006
    ..Blockade of NO synthesis with Nw-nitro-L-arginine more markedly increased blood pressure variability in August rats compared to Wistar rats. The data attest to a certain rigidity of the autonomic cardiovascular regulation in August rats...
  76. ncbi Autonomic nervous system activity during autologous blood donation for orthognathic surgery
    Mika Seto
    Department of Diagnostics and General Care, School of Dentistry, Fukuoka Dental College, Fukuoka, Japan
    J Oral Maxillofac Surg 63:1096-100. 2005
    ....
  77. ncbi Influence of endogenous neuropeptide Y (NPY) on the sympathetic-parasympathetic interaction in the canine heart
    Arnfinn Ilebekk
    Institute for Experimental Medical Research, Ulleval University Hospital, 0407 Oslo, Norway
    J Cardiovasc Pharmacol 46:474-80. 2005
    ....
  78. ncbi Electrophysiological study of infant and adult rats under acute intoxication with fluoroacetamide
    Sergey V Kuznetsov
    I M Sechenov Institute of Evolutionary Physiology and Biochemistry, St Petersburg, Russia
    J Appl Toxicol 27:538-50. 2007
    ....
  79. ncbi Preoperative heart rate variability in relation to surgery outcome in refractory epilepsy
    H Persson
    Department of Clinical Neuroscience, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden
    Neurology 65:1021-5. 2005
    ..This risk seems to be reduced after successful surgery but whether this is an effect of surgery or reflects pre-existing differences between good and poor responders is under debate...
  80. ncbi Dual activation of cardiac sympathetic and parasympathetic components during conditioned fear to context in the rat
    Pascal Carrive
    School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia
    Clin Exp Pharmacol Physiol 33:1251-4. 2006
    ..The vagal activation may act to hold back cardiac acceleration while the animal waits for the aversive stimulus to come...
  81. ncbi [Examinations of the autonomic nervous system. The Danish Society of Clinical Physiology and Nuclear Medicine]
    Jesper Mehlsen
    Klinisk Fysiologisk Nuklearmedicinsk Afdeling, H S Frederiksberg Hospital, DK 2000 Frederiksberg
    Ugeskr Laeger 168:1227. 2006
  82. ncbi A new look at cardiac defense: attention or emotion?
    Jaime Vila
    Departamento de Personalidad de Evaluación y Tratamiento Psicológico, Facultad de Psicologia, Campus La Cartuja s n, 18011 Granada, Spain
    Span J Psychol 6:60-78. 2003
    ..The implications of this new look at cardiac defense are discussed in relation to defensive reactions in natural settings, the brain mechanisms controlling such reactions, and their effects on health and illness...
  83. ncbi Microinjection of a 5-HT3 receptor agonist into the NTS of awake rats inhibits the bradycardic response to activation of the von Bezold-Jarisch reflex
    D M Leal
    Department of Physiology, , , , , Brazil
    Brain Res Bull 54:7-11. 2001
    ..The data of the present study suggest that serotonin acting on 5-HT3 receptors in the NTS may play an important inhibitory neuromodulatory role in the bradycardic response to activation of the von Bezold-Jarisch reflex...
  84. ncbi Effects of nitroglycerin treatment on baroreflex sensitivity and short-term heart rate variability in humans
    Tommaso Gori
    Division of Cardiology, Department of Medicine, Mount Sinai Hospital, and the University Health Network Hospitals, Toronto, Canada
    J Am Coll Cardiol 40:2000-5. 2002
    ..We set out to determine the effect of sustained treatment with nitroglycerin (GTN) on neural modulation of heart rate in humans...
  85. ncbi Autonomic nervous system activity and the state and development of obesity in Japanese school children
    Narumi Nagai
    Laboratory of Applied Physiology, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan
    Obes Res 11:25-32. 2003
    ..We further examined a physiological association between the duration of obesity and the sympatho-vagal activities to scrutinize the nature of ANS alteration as a possible etiologic factor of childhood obesity...
  86. ncbi Separation of heart rate variability components of the autonomic nervous system by utilizing principal dynamic modes
    K H Chon
    State University of New York, Stony Brook, HSC T18, Rm 030, State University of New York at Stony Brook, Stony Brook, NY, 11794 8181, USA
    Nonlinear Dynamics Psychol Life Sci 10:163-85. 2006
    ..The PDM methodology is expected to have an added benefit that diagnosis and prognostication of a patient's health can be determined simply via a non-invasive electrocardiogram...
  87. ncbi Elevated parasympathetic nerve tone in isoproterenol-induced neurally mediated syncope during head-up tilt testing
    A Takei
    First Department of Internal Medicine, Kobe University School of Medicine, Japan
    Jpn Circ J 65:320-4. 2001
    ..The early and persistent increase in parasympathetic nerve tone provoked by isoproterenol plays an important role in enhancing the vasovagal reaction during head-up tilt testing...
  88. ncbi Effect of autonomic blockers on heart period variability in calves: evaluation of the sympathovagal balance
    G Despres
    Adaptation et Comportements Sociaux, URH, Centre INRA de Clermont Theix, 63122, Saint Genes Champanelle, France
    Physiol Res 51:347-53. 2002
    ..VSE, HR, MeanRR and RMSSD were found to be valid indicators of the parasympathetic tone of calves because of large variations due to the drug and low individual variations. No measure reflected the sympathetic tone...
  89. ncbi Acute effects of caffeine on heart rate variability
    Hugo P Sondermeijer
    University of Leiden, Leiden, The Netherlands
    Am J Cardiol 90:906-7. 2002
  90. ncbi Cardiac autonomic denervation and functional response to neurotoxins during acute experimental Chagas' disease in rats
    A L Teixeira
    Departamento de Morfologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
    Auton Neurosci 89:128-32. 2001
    ..Atropine prevented this lower rate. Our results demonstrated sympathetic dysfunction during the acute phase of Trypanosoma cruzi infection in rats, the parasympathetic function being spared...
  91. ncbi Inhomogeneous derangement of cardiac autonomic nerve control in diabetic rats
    Shamarendra Nath Sanyal
    Department of Physiology, Oita Medical University, Japan
    Circ J 66:283-8. 2002
    ....
  92. ncbi Sympathetic blockade significantly improves cardiovascular alterations immediately after spinal cord injury in rats
    G Bravo
    Departamento Farmacobiología, CINVESTAV, IPN, Calzada de los Tenorios 235, Col Granjas Coapa, 14330 Mexico D F, Mexico
    Neurosci Lett 319:95-8. 2002
    ..Likewise, propranolol and pentolinium completely abolished the effects in HR. These data suggest that the early cardiovascular alterations secondary to SCI results from an increased parasympathetic activity and a sympathetic withdrawal...
  93. ncbi Autonomic function in patients with functional dyspepsia assessed by 24-hour heart rate variability
    Sônia Letícia Silva Lorena
    Departamento de Clinica Medica, Universidade Estadual de Campinas, Sao Paulo, Brazil
    Dig Dis Sci 47:27-31. 2002
    ..Our results suggest impaired efferent vagal function in a subgroup of patients with functional dyspepsia. This abnormality may play a role in the pathogenesis of the disease in these patients...
  94. ncbi Neuronal control of heart rate in isolated mouse atria
    J K Choate
    Department of Physiology, PO Box 13F, Monash University, Victoria 3800, Australia
    Am J Physiol Heart Circ Physiol 285:H1340-6. 2003
    ..Activation of ICa,L also appears to contribute to the sympathetic heart rate response. However, the decrease in heart rate with vagal stimulation or carbachol is likely to result primarily from the activation of IK,ACh...
  95. ncbi Erythromycin antagonizes the deceleration of gastric emptying by glucagon-like peptide 1 and unmasks its insulinotropic effect in healthy subjects
    Juris J Meier
    Department of Medicine, Ruhr University, Bochum, Germany
    Diabetes 54:2212-8. 2005
    ..counteracts the deceleration of gastric emptying caused by GLP-1, probably by interacting with the parasympathetic nervous system (pancreatic polypeptide responses)...
  96. ncbi [Heart rate variability. Applications in psychiatry]
    D Servant
    Service de Psychiatrie Générale, Hôpital Fontan, CHRU de Lille, Rue Verhaeghe, 59037 Lille Cedex, France
    Encephale 35:423-8. 2009
    The autonomic nervous system sends messages through the sympathetic and parasympathetic nervous system. The sympathetic nervous system innervates the cardioaccelerating center of the heart, the lungs (increased ventilatory rhythm and ..
  97. ncbi Effect of sensory stimulation (acupuncture) on sympathetic and parasympathetic activities in healthy subjects
    E Haker
    Department of Physical Therapy, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    J Auton Nerv Syst 79:52-9. 2000
    ..The purpose of this study was to investigate to what extent acupuncture applied into the thenar muscle and into the cavum concha of the ear induced changes in the sympathetic and/or parasympathetic nervous system in healthy subjects.
  98. ncbi Autonomic nervous system function in chronic hypotension associated with Bartter and Gitelman syndromes
    Michelangelo Sartori
    Department of Clinical and Experimental Medicine, Clinica Medica 4, University of Padova, Italy
    Am J Kidney Dis 49:330-5. 2007
    ..We tested sympathetic and parasympathetic nervous system function in 4 patients with Bartter and Gitelman syndromes with chronic hypotension...
  99. ncbi Cardiotoxicity of digitalis glycosides: roles of autonomic pathways, autacoids and ion channels
    A T Demiryurek
    Department of Pharmacology, Faculty of Medicine, University of Gaziantep, Gaziantep, Turkey
    Auton Autacoid Pharmacol 25:35-52. 2005
    ..2 The involvement of the sympathetic and parasympathetic nervous system in digitalis cardiac toxicity is reviewed...
  100. pmc Muscarinic receptors participation in angiogenic response induced by macrophages from mammary adenocarcinoma-bearing mice
    Eulalia de la Torre
    Departamento de Inmunobiologia, Instituto de Oncología A H Roffo, Universidad de Buenos Aires, Buenos Aires, Argentina
    Breast Cancer Res 7:R345-52. 2005
    ..Here we investigate the ability of the parasympathetic nervous system to modulate angiogenesis induced by TMps through the activation of the muscarinic acetylcholine ..
  101. pmc Intrinsic innervation and dopaminergic markers after experimental denervation in rat thymus
    F Mignini
    Dip Medicina Clinica e Sperimentale, Lab Anatomia Umana, Univ Piemonte Oriental, Novara, Italy
    Eur J Histochem 54:e17. 2010
    ..In the subcapsular and septal region, no parenchymal nerve branching, belonging to sympathetic or parasympathetic nervous system was noted...

Research Grants62

  1. Respiratory and autonomic plasticity following intermittent hypoxia
    JASON HAROLD MATEIKA; Fiscal Year: 2012
    ..Similarly, LTF of SNSA activity and possibly long-term depression (LTD) of parasympathetic nervous system activity (PNSA) could ultimately lead to persistent increases in blood pressure and heart rate ..
  2. Hostility, PTSD and Physical Health Risk Factors
    Jean C Beckham; Fiscal Year: 2013
    ..Although previous work has demonstrated a relationship between PTSD and reduced parasympathetic nervous system control of the heart under controlled laboratory conditions, no study has evaluated autonomic ..
  3. Adhesion Mechanisms Mediating Sickle Cell Vasooclusion In Vivo
    Paul S Frenette; Fiscal Year: 2013
    ..In addition to the SNS, our preliminary data also suggest a role for parasympathetic nervous system (PNS) in leukocyte recruitment...
  4. PARASYMPATHETIC DYSFUNCTION IN OBESITY: EFFECT OF CHOLESTEROL ON VAChT
    Yifan Li; Fiscal Year: 2013
    ..In obesity, parasympathetic nervous system (PSNS) regulation of the heart is markedly attenuated 8-10, which may contribute to obesity-related ..
  5. Radiation Combined Injury: Mechanisms and Therapeutic Approaches
    Ping Wang; Fiscal Year: 2012
    ..The action of ghrelin in sepsis also involves the parasympathetic nervous system, as vagotomy prevents its beneficial effects...
  6. NEURAL REGULATION OF PREPARTUM CERVICAL RIPENING
    Steven M Yellon; Fiscal Year: 2013
    ..image analyses approaches provided support for the novel concept that innervation by the central parasympathetic nervous system is critical for the normal timing of birth...
  7. The Treatment of Depression with Yoga and Walking
    CHRIS CONWAY STREETER; Fiscal Year: 2013
    ..There is evidence tha negative emotions are related to decreased activity in the parasympathetic nervous system (PNS) as measured by vagal tone...
  8. Reversing the Autonomic Nervous System Imbalance in Overweight Individuals
    GENEVIEVE ANNA WOODARD; Fiscal Year: 2010
    ..a quantitative measurement of both branches of the ANS: the sympathetic nervous system (SNS) and parasympathetic nervous system (PNS)...
  9. Activation of the Trigeminovascular Pathway
    Rami Burstein; Fiscal Year: 2011
    ..Under hypothesis 3, we will test whether the parasympathetic nervous system mediates sustained activation/sensitization of meningeal nociceptors induced by CSD...
  10. Trigeminal-autonomic relations in ocular homeostasis
    David A Bereiter; Fiscal Year: 2013
    ..all tissues of the eye and serve as the afferent limb for many protective reflexes mediated by the parasympathetic nervous system (PaNS)...
  11. Modulation of Odorant Receptor Function
    Hiroaki Matsunami; Fiscal Year: 2013
    ..regulated by another GPCR, M3R, which is activated by acetylcholine, the key neurotransmitter of the parasympathetic nervous system. An understanding of the interactions between the neurotransmitter receptor and the peripheral ..
  12. Stress, Autonomic Reactivity, and Mental Health in Low Income, Latino Children
    ABBEY DIANE ALKON; Fiscal Year: 2010
    ..the activation of the sympathetic nervous system (the flight or fight response) and withdrawal of the parasympathetic nervous system (the resting response)...
  13. DETERMINANTS OF SODIUM RETENTION IN CIRRHOSIS
    WILLIAM RECTOR; Fiscal Year: 1992
    ..resistance (reflections of arterial BV); 5) left atrial size (central BV); 6) portal-systemic shunt fraction; 7) plasma concentration of PG; 8) sympathetic and parasympathetic nervous system function; and 9) liver metabolic capacity.
  14. Radiation Combined Injury: Mechanisms and Therapeutic Approaches
    Ping Wang; Fiscal Year: 2009
    ..The action of ghrelin in sepsis also involves the parasympathetic nervous system, as vagotomy prevents its beneficial effects...
  15. TRH in mediating the bradycardia of caloric restriction
    Steven Swoap; Fiscal Year: 2005
    ..in cardiovascular biology concerning the roles of thyrotropin releasing hormone, thyroid hormones, the parasympathetic nervous system, and the sympathetic nervous system in the bradycardia of caloric restriction in mice...
  16. Integration by Airway Parasympathic Ganglia Neurons
    Allen Myers; Fiscal Year: 2004
    ..to provide knowledge of how autonomic tone is regulated in the airway, especially that provided by the parasympathetic nervous system. Control of smooth muscle in the trachea and bronchi is predominantly by nerve fibers that emanate ..
  17. Intrinsic and Extrinsic Effects on Trajectories of Infants' Vagal Functioning
    Cathi Propper; Fiscal Year: 2009
    ..for state, motor, and emotion control may have certain underlying physiological processes in the parasympathetic nervous system that play a role in their functioning...
  18. CARDIAC AUTONOMIC CONTROL IN CHILDREN OF HIV+ MOTHERS
    Steven Lipshultz; Fiscal Year: 1993
    ..P2C2 clinical centers to capture noninvasively the time varying contributions of the sympathetic and parasympathetic nervous system to the control of heart rate throughout the course of a day...
  19. NEUROIMMUNOLOGY OF AED IN OCULAR HSV-1 INFECTION
    Daniel Carr; Fiscal Year: 2001
    ..The activation of the hypothalamic pituitary adrenal axis and the sympathetic/parasympathetic nervous system are thought to be involved in inducing reactivation of latent HSV-l...
  20. EXERCISE TO IMPROVE HRV IN SUDDEN CARDIAC ARREST
    CYNTHIA DOUGHERTY; Fiscal Year: 2004
    ..My interest is in determining if exercise will affect cardiac parasympathetic nervous system regulation and therefore convey cardioprotective effects that will subsequently influence rates of ..
  21. Development of Epibranchial Placodes and Ganglia in Zebrafish
    Alex Nechiporuk; Fiscal Year: 2010
    ..Relevance: Sensory component of the parasympathetic nervous system has been implicated in many human disorders, including chronic obstructive pulmonary disease, ..
  22. MODEL OF ACUTE AND CHRONIC AIRWAY DISEASE
    CAROL HIRSHMAN; Fiscal Year: 1990
    ..We have shown that airway hyperreactivity in these dogs is not directly associated with increased parasympathetic nervous system activity, increased lung epithelial permeability in the absence of airway challenge, or an intrinsic ..
  23. Genetic remodeling of Vagal Afferent Organization
    Edward Fox; Fiscal Year: 2009
    The vagus or Xth cranial nerve contains both the sensory and motor divisions of the parasympathetic nervous system that regulate the heart, lungs and digestive tract - regulatory activities that are required to sustain life...
  24. LM AND EM MORPHOLOGY OF SACRAL PARASYMPATHETIC NEURONS
    Charles Morgan; Fiscal Year: 1990
    The parasympathetic nervous system exerts the major control over the excretory and sexual reflexes...
  25. ANTISOCIAL CHILDREN: MARITAL & PHYSIOLOGICAL PROCESSES
    LYNN KATZ; Fiscal Year: 2003
    ..of marital, parent-child and child-peer systems and physiological assessments of sympathetic and parasympathetic nervous system activity will be systematically applied in one study to examine interpersonal and intrapersonal risk ..
  26. Brainstem nAChR Subtypes & Their Effect on GI Function
    RICHARD GILLIS; Fiscal Year: 2006
    ..These and future data obtained from pursuing our Specific Aims will extend current understanding of the different receptor mediated effects of nicotine on parasympathetic nervous system control of the upper GI tract.
  27. PHOTOPERIODIC CONTROL OF OBESITY
    Timothy Bartness; Fiscal Year: 2008
    ..RESEARCH GRANT TABLE OF CONTENTS Page Numbers 1 Face Page .................................................................................................................................................. Description, ..
  28. THE CPA: SOMATIC AND AUTONOMIC SYSTEMS
    W Panneton; Fiscal Year: 2004
    ..Understanding the brainstem mechanisms governing he vascular constriction after either of these somatic stimuli may provide a neurological explanation for this. Such knowledge may lead to an understanding of essential hypertension. ..
  29. Cardiovascular Response to Glutamate Nitric Oxide
    WILLIAM TALMAN; Fiscal Year: 2006
    ..e. on nNOS immunoreactive dendrites or neurons in NTS. ..
  30. Antipsychotics: Temporal Effects on Cognitive Function
    Alvin Terry; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  31. NEUROTROPHINS, HORMONES AND POSTPAROUS INCONTINENCE
    Peter Smith; Fiscal Year: 2004
    ....
  32. Cotinine for Cognitive Impairment in Neurological and Neuropsychiatric Disorders
    Alvin V Terry; Fiscal Year: 2010
    ..The partly translational design of the study will provide results leading to eventual clinical trials with cotinine or a relevant analog. ..
  33. Mechanisms of Sympathetic Axon Pruning
    Peter G Smith; Fiscal Year: 2010
    ..Findings will be pertinent to understanding both organizing principles related to normal nervous system plasticity, and to disturbances in innervation in certain disease states. ..
  34. Heart Period Variability in Critically Ill VLBW Infants
    Sandra Smith; Fiscal Year: 2003
    ..of heart period power, (2) test the impact of developmental care on heart period power, and (3) develop and test interventions that would promote balance in the low- and high-frequency regions of heart period power ..
  35. NGF and Post-Infarct Sympathetic Neuroplasticity
    Peter Smith; Fiscal Year: 2009
    ....
  36. SYMPATHETIC NERVE REMODELING IN THE ADULT UTERUS
    Peter Smith; Fiscal Year: 2003
    ..abstract_text> ..
  37. Mindfulness-based Stress Reduction For High Blood Pressure
    Joel Hughes; Fiscal Year: 2007
    ..Accrual rates, acceptance of randomization, treatment adherence, treatment fidelity, and patient satisfaction with treatment will be evaluated. [unreadable] [unreadable] [unreadable]..
  38. Emotion Regulation in Relationships during Separation
    Lisa Diamond; Fiscal Year: 2003
    ..This information will make a significant contribution to research on the multiple biobehavioral processes through which close relationships influence day-to-day emotion regulation and long-term psychological well-being. ..
  39. ACUTE BRAIN INJURY, MECHANISMS AND PROTECTION
    John Olney; Fiscal Year: 2001
    ..The long term goals are to clarify the underlying mechanisms and develop improved methods of treating human pediatric acute brain injury conditions. ..
  40. An animal model for age-related degeneration
    ANN CHARLOTTE ESTHER GRANHOLM; Fiscal Year: 2010
    ..The overall purpose of these studies is to investigate endogenous defense mechanisms as well as the degenerative process in itself, to explore if early intervention strategies can be employed. ..
  41. LIPID & PROTEIN PO4 TURNOVER IN IRIS OF THE EYE
    ATA ABDEL LATIF; Fiscal Year: 2002
    ..the sympathetic nervous system, which governs the formation of cAMP and muscle relaxation, and the parasympathetic nervous system, which governs the generation of IP3-, DAG-, Ca2+, and muscle contraction...
  42. LONG TERM RECORDING FROM AFFERENT TASTE FIBERS
    Robert Bradley; Fiscal Year: 2003
    ..abstract_text> ..
  43. SEROTONERGIC REGULATION OF INSULIN LIKE GROWTH FACTORS
    Jean Lauder; Fiscal Year: 2003
    ....
  44. NEURAL STRUCTURE FUNCTION RELATIONSHIPS IN RETINA
    Franklin Amthor; Fiscal Year: 2003
    ....
  45. Confer. Neural Mechanisms in Cardiovascular Regulation
    MARK CHAPLEAU; Fiscal Year: 2002
    ..Time will be allotted for informal discussions and social interaction. Scientists from the United States and other countries, young investigations and women are well-represented in the program. ..
  46. International meeting Neural Transplantation and Repair
    ANN CHARLOTTE GRANHOLM BENTLEY; Fiscal Year: 2002
    ..In addition, previous statistics demonstrate that we have favored women and minorities in the past (33% of the travel award recipients for this years' meeting were women, and women serve on all the committees in our organization). ..
  47. HOSTILITY REDUCTION AND AUTONOMIC CONTROL OF THE HEART
    Richard Sloan; Fiscal Year: 2004
    ....
  48. MULTI-LEVEL ANALYSIS OF URBAN CHILDHOOD ASTHMA RISK
    Rosalind Wright; Fiscal Year: 2004
    ..An additional feature of the proposal is the opportunity to involve under represented minority students (predoctoral and summer interns) from two NIH-funded grants whose principal investigator is a co-investigator on this proposal. ..
  49. Neurotransmission evoked by 5HT-dependent luminal factor
    Ying Li; Fiscal Year: 2005
    ..Finally, we will examine the roles of various neurotransmitters in the DMN in the mediation of pancreatic secretion stimulated by luminal 5HT-dependent factors using a conscious rat model. ..
  50. WAGES: Workplace Activity for Employee Goal Setting
    RODNEY DISHMAN; Fiscal Year: 2006
    ..The project will implement and rigorously evaluate a multilevel physical activity intervention that has potential for broad application to workplace health promotion. ..
  51. Fat Metabolism During Exercise in Obesity
    EDWARD MELANSON; Fiscal Year: 2007
    ..I believe the results from these studies will lead directly to additional studies to further explain why exercise may be important in the prevention and treatment of obesity. ..
  52. GENETICS OF ADHD
    Josephine Elia; Fiscal Year: 2007
    ..Dr. Douglas Levinson will provide mentoring in statistical methods and data analyses and Dr. Judith Rapoport will provide mentoring in defining novel phenotypic definitions for ADHD. ..
  53. Neural Control of Airway Responses in Early Life
    RICHARD DEY; Fiscal Year: 2009
    ..abstract_text> ..
  54. Does Nasal Stimulation Activate Presympathetic Neurons?
    Paul McCulloch; Fiscal Year: 2005
    ..As such, this research has implications for understanding the etiology of neurogenic hypertension. ..
  55. Epidemiology and Mechanisms of Fecal Incontinence
    Adil Bharucha; Fiscal Year: 2005
    ..abstract_text> ..
  56. HEART RATE VARIABILITY IN SLEEP-DISORDERED BREATHING
    MICHAEL KHOO; Fiscal Year: 2005
    ....
  57. Pharmacotherapy for Minor Depression
    Robert Howland; Fiscal Year: 2004
    ..The results of this study will have profound public health implications by improving our understanding of the efficacy of SJW and standard antidepressants for the treatment of MinorD. ..
  58. AFFERENT PLASTICITY UNDERLYING URETHRAL AND PELVIC PAIN
    Naoki Yoshimura; Fiscal Year: 2010
    ..This is recognized as a high priority in the urologic care of patients with IC/CPPS. ..
  59. COMPONENTS OF PUPILLARY DILATION AND COGNITION
    STUART ROBERT STEINHAUER; Fiscal Year: 2010
    ..Findings will further pinpoint functional systems to be examined using current and future imaging technologies. ..
  60. Coronary Physiology
    Eric O Feigl; Fiscal Year: 2010
    ..This is a resubmission of RO1 HL 082781-01-A1 (This time as a modular grant.) ..