autonomic nervous system

Summary

Summary: The enteric, parasympathetic, and sympathetic nervous systems taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the central nervous system, especially the hypothalamus and the solitary nucleus, which receive information relayed from VISCERAL AFFERENTS; these and related central and sensory structures are sometimes (but not here) considered to be part of the autonomic nervous system itself.

Top Publications

  1. ncbi The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors
    Julian F Thayer
    The Ohio State University, Department of Psychology, 1835 Neil Avenue, Columbus, Ohio 43210, USA
    Int J Cardiol 141:122-31. 2010
  2. ncbi Diabetic cardiovascular autonomic neuropathy
    Aaron I Vinik
    Strelitz Diabetes Research Institute, 855 W Brambleton Avenue, Norfolk, VA 23510, USA
    Circulation 115:387-97. 2007
  3. ncbi Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysis
    Andrew H Kemp
    School of Psychology, University of Sydney, Sydney, Australia
    Biol Psychiatry 67:1067-74. 2010
  4. ncbi Heart rate variability: a review
    U Rajendra Acharya
    Department of ECE, Ngee Ann Polytechnic, 535 Clementi Road, Singapore, Singapore 599 489
    Med Biol Eng Comput 44:1031-51. 2006
  5. ncbi Autonomic nervous system activity in emotion: a review
    Sylvia D Kreibig
    Department of Psychology, University of Geneva and Swiss Center for Affective Sciences, Geneva, Switzerland
    Biol Psychol 84:394-421. 2010
  6. ncbi An autonomic flexibility-neurovisceral integration model of anxiety and cardiac vagal tone
    Bruce H Friedman
    Department of Psychology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061 0436, USA
    Biol Psychol 74:185-99. 2007
  7. ncbi Cardiovascular side-effects of antipsychotic drugs: the role of the autonomic nervous system
    Joanne Y T Leung
    Department of Pharmacology, University of British Columbia, 2176 Health Sciences Mall, Vancouver, B C V6T1Z3, Canada
    Pharmacol Ther 135:113-22. 2012
  8. ncbi Heart-brain interactions in cardiac arrhythmias: role of the autonomic nervous system
    Douglas P Zipes
    Division of Cardiology, Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Cleve Clin J Med 75:S94-6. 2008
  9. ncbi Heart rate variability explored in the frequency domain: a tool to investigate the link between heart and behavior
    Nicola Montano
    Department of Clinical Science, Luigi Sacco Hospital, University of Milan, Milan, Italy
    Neurosci Biobehav Rev 33:71-80. 2009
  10. ncbi Effects of yoga on the autonomic nervous system, gamma-aminobutyric-acid, and allostasis in epilepsy, depression, and post-traumatic stress disorder
    C C Streeter
    Department of Psychiatry, Boston University School of Medicine, Boston, MA 02118, USA
    Med Hypotheses 78:571-9. 2012

Detail Information

Publications392 found, 100 shown here

  1. ncbi The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors
    Julian F Thayer
    The Ohio State University, Department of Psychology, 1835 Neil Avenue, Columbus, Ohio 43210, USA
    Int J Cardiol 141:122-31. 2010
    ..We close with a suggestion that a model of autonomic imbalance may provide a unifying framework within which to investigate the impact of risk factors, including psychosocial factors and work stress, on cardiovascular disease...
  2. ncbi Diabetic cardiovascular autonomic neuropathy
    Aaron I Vinik
    Strelitz Diabetes Research Institute, 855 W Brambleton Avenue, Norfolk, VA 23510, USA
    Circulation 115:387-97. 2007
  3. ncbi Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysis
    Andrew H Kemp
    School of Psychology, University of Sydney, Sydney, Australia
    Biol Psychiatry 67:1067-74. 2010
    ..The objective of the current report is to examine with meta-analysis the impact of depression and antidepressant treatment on HRV in depressed patients without CVD...
  4. ncbi Heart rate variability: a review
    U Rajendra Acharya
    Department of ECE, Ngee Ann Polytechnic, 535 Clementi Road, Singapore, Singapore 599 489
    Med Biol Eng Comput 44:1031-51. 2006
    ..HR against time axis) has become a popular noninvasive tool for assessing the activities of the autonomic nervous system. Computer based analytical tools for in-depth study of data over daylong intervals can be very useful in ..
  5. ncbi Autonomic nervous system activity in emotion: a review
    Sylvia D Kreibig
    Department of Psychology, University of Geneva and Swiss Center for Affective Sciences, Geneva, Switzerland
    Biol Psychol 84:394-421. 2010
    b>Autonomic nervous system (ANS) activity is viewed as a major component of the emotion response in many recent theories of emotion...
  6. ncbi An autonomic flexibility-neurovisceral integration model of anxiety and cardiac vagal tone
    Bruce H Friedman
    Department of Psychology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061 0436, USA
    Biol Psychol 74:185-99. 2007
    ..the qualities of response flexibility and inhibition across multiple levels, incorporating central and autonomic nervous system mechanisms of environmental engagement, as well as principles derived from non-linear dynamics...
  7. ncbi Cardiovascular side-effects of antipsychotic drugs: the role of the autonomic nervous system
    Joanne Y T Leung
    Department of Pharmacology, University of British Columbia, 2176 Health Sciences Mall, Vancouver, B C V6T1Z3, Canada
    Pharmacol Ther 135:113-22. 2012
    ..The direct and indirect effects of antipsychotic drugs on the cardiovascular system and their possible mechanisms of action are discussed in this review, where both preclinical and clinical findings are integrated...
  8. ncbi Heart-brain interactions in cardiac arrhythmias: role of the autonomic nervous system
    Douglas P Zipes
    Division of Cardiology, Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Cleve Clin J Med 75:S94-6. 2008
    The autonomic nervous system plays an important role in the genesis of ventricular arrhythmias and sudden cardiac death. Evidence is substantial for a neural component in sudden cardiac death...
  9. ncbi Heart rate variability explored in the frequency domain: a tool to investigate the link between heart and behavior
    Nicola Montano
    Department of Clinical Science, Luigi Sacco Hospital, University of Milan, Milan, Italy
    Neurosci Biobehav Rev 33:71-80. 2009
    ..heart failure) and in presence of rapid and transients changes or coactivation of the two branches of autonomic nervous system, the development of new non-linear approaches seems to provide a new perspective in investigating neural ..
  10. ncbi Effects of yoga on the autonomic nervous system, gamma-aminobutyric-acid, and allostasis in epilepsy, depression, and post-traumatic stress disorder
    C C Streeter
    Department of Psychiatry, Boston University School of Medicine, Boston, MA 02118, USA
    Med Hypotheses 78:571-9. 2012
    ..It is hypothesized that stress induces (1) imbalance of the autonomic nervous system (ANS) with decreased parasympathetic nervous system (PNS) and increased sympathetic nervous system (SNS) ..
  11. pmc Atrial fibrillation begets atrial fibrillation: autonomic mechanism for atrial electrical remodeling induced by short-term rapid atrial pacing
    Zhibing Lu
    Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China
    Circ Arrhythm Electrophysiol 1:184-92. 2008
    ..We sought to evaluate the contribution of the intrinsic cardiac autonomic nervous system in acute atrial electrical remodeling and AF induced by 6-hour rapid atrial pacing.
  12. pmc Neural regulation of endocrine and autonomic stress responses
    Yvonne M Ulrich-Lai
    Department of Psychiatry, University of Cincinnati, Ohio 45237 0506, USA
    Nat Rev Neurosci 10:397-409. 2009
    ....
  13. ncbi Beyond heart rate variability: vagal regulation of allostatic systems
    Julian F Thayer
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Ann N Y Acad Sci 1088:361-72. 2006
    The autonomic nervous system (ANS) plays a role in a wide range of somatic and mental diseases...
  14. ncbi Software for advanced HRV analysis
    Juha Pekka Niskanen
    Department of Applied Physics, University of Kuopio, P O Box 1627, FIN 70211 Kuopio, Finland
    Comput Methods Programs Biomed 76:73-81. 2004
    ..Together with a modern heart rate monitor capable of recording RR intervals this freely distributed program forms a complete low-cost HRV measuring and analysis system...
  15. ncbi Heart rate variability as a measure of autonomic regulation of cardiac activity for assessing stress and welfare in farm animals -- a review
    Eberhard von Borell
    Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle Wittenberg, 06108 Halle, Germany
    Physiol Behav 92:293-316. 2007
    ..rate variability (HRV) is a non-invasive technique that can be used to investigate the functioning of the autonomic nervous system, especially the balance between sympathetic and vagal activity...
  16. ncbi To err is autonomic: error-related brain potentials, ANS activity, and post-error compensatory behavior
    Greg Hajcak
    Department of Psychology, University of Delaware, Newark, Delaware 19716, USA
    Psychophysiology 40:895-903. 2003
    ..cortex (ACC)--a frontal structure implicated in both cognitive and affective processing, as well as autonomic nervous system (ANS) modulation...
  17. ncbi A model of neurovisceral integration in emotion regulation and dysregulation
    J F Thayer
    National Institute of Aging Gerontology Research Center, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA
    J Affect Disord 61:201-16. 2000
    ..From this perspective, the relative sympathetic activation seen in anxiety disorders may represent dis-inhibition due to faulty inhibitory mechanisms...
  18. ncbi Heart rate variability: measurement and clinical utility
    Robert E Kleiger
    Washington University School of Medicine, St Louis, MO, USA
    Ann Noninvasive Electrocardiol 10:88-101. 2005
    ..by ventilation, baroreflexes, and other genetic and environmental factors that are mediated through the autonomic nervous system. Short term electrocardiographic recordings (5 to 15 minutes), made under controlled conditions, e.g...
  19. ncbi The role of vagal function in the risk for cardiovascular disease and mortality
    Julian F Thayer
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Biol Psychol 74:224-42. 2007
    ....
  20. ncbi Cardiac neuronal hierarchy in health and disease
    J Andrew Armour
    Department of Pharmacology, Faculty of Medicine, University of Montreal, Montreal, Quebec, H3C 3J7 Canada
    Am J Physiol Regul Integr Comp Physiol 287:R262-71. 2004
    ....
  21. ncbi Effect of aging on gender differences in neural control of heart rate
    T B Kuo
    Institute of Neuroscience, Tzu Chi College of Medicine and Humanities, Hualien 970, Taiwan, Republic of China
    Am J Physiol 277:H2233-9. 1999
    ..The gender-related difference in parasympathetic regulation diminishes after age 50 yr, whereas a significant time delay for the disappearance of sympathetic dominance occurs in men...
  22. ncbi Basic notions of heart rate variability and its clinical applicability
    Luiz Carlos Marques Vanderlei
    Faculty of Health and Technology, FCT UNESP, Presidente Prudente, Sao Paulo, SP, Brazil
    Rev Bras Cir Cardiovasc 24:205-17. 2009
    b>Autonomic nervous system (ANS) plays an important role in the regulation of the physiological processes of the human organism during normal and pathological conditions...
  23. ncbi Influence of age, the autonomic nervous system and anxiety on QT-interval variability
    G Piccirillo
    Dipartimento di Scienze dell Invecchiamento, I Clinica Medica, Policlinico Umberto I, 00161 Rome, Italy
    Clin Sci (Lond) 101:429-38. 2001
    ..In the present study we investigated the influence of aging and the autonomic nervous system on QT-interval variability in healthy subjects...
  24. pmc Low-frequency power of heart rate variability is not a measure of cardiac sympathetic tone but may be a measure of modulation of cardiac autonomic outflows by baroreflexes
    David S Goldstein
    Clinical Neurocardiology Section, Clinical Neurosciences Program, Division of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1620, USA
    Exp Physiol 96:1255-61. 2011
    ..Manipulations and drugs that change LF power or LF:HF may do so not by affecting cardiac autonomic outflows directly but by affecting modulation of those outflows by baroreflexes...
  25. ncbi Exercise training associated with diet improves heart rate recovery and cardiac autonomic nervous system activity in obese children
    D M Prado
    Medical School, Department of Endocrinology, University of Sao Paulo, Brazil
    Int J Sports Med 31:860-5. 2010
    ..diet (D) improves both heart rate recovery at 1 min (Δ HRR1) cfter an exercise test, and cardiac autonomic nervous system activity (CANSA) in obese children; 2) Diet and exercise training (DET) combined leads to greater ..
  26. ncbi Hypothalamic control of energy metabolism via the autonomic nervous system
    A Kalsbeek
    Department of Endocrinology and Metabolism, Academic Medical Center AMC, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands
    Ann N Y Acad Sci 1212:114-29. 2010
    ....
  27. ncbi The polyvagal theory: phylogenetic substrates of a social nervous system
    S W Porges
    Department of Psychiatry, University of Illinois at Chicago, 60612-7327, USA
    Int J Psychophysiol 42:123-46. 2001
    The evolution of the autonomic nervous system provides an organizing principle to interpret the adaptive significance of physiological responses in promoting social behavior...
  28. ncbi Respiratory sinus arrhythmia: why does the heartbeat synchronize with respiratory rhythm?
    Fumihiko Yasuma
    Department of Internal Medicine, Suzuka National Hospital, 3 2 1 Kasado, Suzuka 513 8501, Japan
    Chest 125:683-90. 2004
    ..RSA or heart rate variability in synchrony with respiration is a biological phenomenon, which may have a positive influence on gas exchange at the level of the lung via efficient ventilation/perfusion matching...
  29. ncbi The Polyvagal Theory: phylogenetic contributions to social behavior
    Stephen W Porges
    Brain Body Center, Psychiatric Institute, Department of Psychiatry, University of Illinois at Chicago, 1601 W Taylor Street, M C 912, Chicago, IL 60612, USA
    Physiol Behav 79:503-13. 2003
    ..builds on these early findings by MacLean and focuses on the link between phylogenetic changes in the autonomic nervous system and social behavior...
  30. ncbi Effects of propranolol on recovery of heart rate variability following acute myocardial infarction and relation to outcome in the Beta-Blocker Heart Attack Trial
    Rachel Lampert
    Department of Medicine, School of Medicine, Yale University, New Haven, Connecticut 06520, USA
    Am J Cardiol 91:137-42. 2003
    ..These findings may elucidate the mechanisms by which beta blockers decrease mortality and reduce the early morning risk of sudden death after acute myocardial infarction...
  31. ncbi Neural correlates of heart rate variability during emotion
    Richard D Lane
    Department of Psychiatry, University of Arizona, Tucson, AZ, USA
    Neuroimage 44:213-22. 2009
    ..No statistically significant asymmetries were observed. Our findings are consistent with the view that the medial visceromotor network is a final common pathway by which emotional and cognitive functions recruit autonomic support...
  32. ncbi Perturbed autonomic nervous system function in metabolic syndrome
    Nicholas Tentolouris
    1st Department of Propaedeutic Medicine, Athens University Medical School, Athens, Greece
    Neuromolecular Med 10:169-78. 2008
    ..Subjects with metabolic syndrome have autonomic nervous system dysfunction characterized by predominance of the sympathetic nervous system in many organs, i.e...
  33. ncbi The yin and yang of cardiac autonomic control: vago-sympathetic interactions revisited
    J F R Paton
    Department of Physiology, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK
    Brain Res Brain Res Rev 49:555-65. 2005
    ..This may be important when pumping blood into a constricted vascular tree such as is the case during the diving response. We discuss that in some instances, high drive to the heart from both autonomic limbs may also be arrhythmogenic...
  34. ncbi Dysregulation of arousal and amygdala-prefrontal systems in paranoid schizophrenia
    Leanne M Williams
    The Brain Dynamics Centre, Westmead Hospital and University of Sydney, NSW, Australia
    Am J Psychiatry 161:480-9. 2004
    ..It was predicted that paranoid patients would be distinguished by a disjunction of hyperarousal but reduced amygdala and medial prefrontal activity relative to both healthy comparison subjects and patients with nonparanoid schizophrenia...
  35. ncbi Depression, the autonomic nervous system, and coronary heart disease
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Psychosom Med 67:S29-33. 2005
    ..Dysregulation of the autonomic nervous system (ANS) may explain why depressed patients are at increased risk...
  36. ncbi Functional assessment of heart rate variability: physiological basis and practical applications
    Jiri Pumprla
    Research Group Functional Rehabilitation, Institute of Biomedical Engineering and Physics, University of Vienna, General Hospital, AKH 4L, Waehringer Guertel 18 20, A 1090, Vienna, Austria
    Int J Cardiol 84:1-14. 2002
    The autonomic nervous system dynamically controls the response of the body to a range of external and internal stimuli, providing physiological stability in the individual...
  37. ncbi Mother and child in synchrony: thermal facial imprints of autonomic contagion
    Sjoerd J Ebisch
    Institute of Advanced Biomedical Technologies, G d Annunzio Foundation, Chieti, Italy
    Biol Psychol 89:123-9. 2012
    ..These findings support a multidimensional approach for the comprehension of emotional parent-child relationships...
  38. ncbi Oxytocin, vasopressin and sociality
    C Sue Carter
    The Brain Body Center, Department of Psychiatry, 1601 W Taylor St MC 912, University of Illinois at Chicago, Chicago, IL, USA
    Prog Brain Res 170:331-6. 2008
    ..e. social isolation)...
  39. pmc What do we know and we do not know about cardiovascular autonomic neuropathy in diabetes
    Rodica Pop-Busui
    Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA
    J Cardiovasc Transl Res 5:463-78. 2012
    ..This review covers current understanding and gaps in that understanding of the clinical implications of CAN and prevention and treatment of CAN...
  40. ncbi Autonomic control of the cardiovascular system during acclimatization to high altitude: effects of sildenafil
    Jérémy Cornolo
    Laboratoire Réponses Cellulaires et Fonctionnelles à l Hypoxie, Universite Paris 13, 93017 Bobigny, France
    J Appl Physiol 97:935-40. 2004
    ..Sil had no deleterious effects on the cardiovascular response to high-altitude exposure and its control by the autonomic nervous system.
  41. ncbi The autonomic nervous system in cardiac electrophysiology: an elegant interaction and emerging concepts
    Suraj Kapa
    Division of Cardiology, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Cardiol Rev 18:275-84. 2010
    The autonomic nervous system plays an integral role in the modulation of normal cardiac electrophysiology...
  42. pmc The autonomic nervous system at high altitude
    Roger Hainsworth
    Institute for Cardiovascular Research, University of Leeds, Leeds, UK
    Clin Auton Res 17:13-9. 2007
    ..Excessive hypoxia due to peripheral chemoreceptor dysfunction has been suggested as a cause. The hyperviscous blood leads to pulmonary hypertension, symptoms of cerebral hypoperfusion, and eventually right heart failure and death...
  43. pmc Minireview: The role of the autonomic nervous system in mediating the glucagon response to hypoglycemia
    Gerald J Taborsky
    Veterans Affairs Puget Sound Health Care System, University of Washington, Seattle, Washington 98108, USA
    Endocrinology 153:1055-62. 2012
    ..In nondiabetic individuals, hypoglycemia activates the autonomic nervous system, which in turn mediates the majority of the glucagon response to moderate and marked hypoglycemia...
  44. ncbi Hypothalamic mechanisms coordinating cardiorespiratory function during exercise and defensive behaviour
    R A L Dampney
    School of Medical Sciences Physiology and Bosch Institute, The University of Sydney, NSW 2006, Australia
    Auton Neurosci 142:3-10. 2008
    ..Finally, we discuss the possible role of the DMH in generating circadian rhythms in arterial blood pressure and heart rate, and also in generating longer-term increases in sympathetic activity in some types of hypertension...
  45. pmc Oxytocin protects against negative behavioral and autonomic consequences of long-term social isolation
    Angela J Grippo
    Dept Psychology, Northern Illinois University, PM 357, DeKalb, IL 60115, United States
    Psychoneuroendocrinology 34:1542-53. 2009
    ....
  46. ncbi The central autonomic nervous system: conscious visceral perception and autonomic pattern generation
    Clifford B Saper
    Department of Neurology and Program in Neuroscience, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215, USA
    Annu Rev Neurosci 25:433-69. 2002
    The overall organization of the peripheral autonomic nervous system has been known for many decades, but the mechanisms by which it is controlled by the central nervous system are just now coming to light...
  47. ncbi Non-stationarities significantly distort short-term spectral, symbolic and entropy heart rate variability indices
    Valentina Magagnin
    Laboratorio di Modellistica di Sistemi Complessi, Dipartimento di Tecnologie per la Salute, Istituto Ortopedico Galeazzi, Universita degli Studi di Milano, Via R Galeazzi 4, Milan, Italy
    Physiol Meas 32:1775-86. 2011
    ..The study suggests that non-stationarities increase the likelihood to overestimate the contribution of sympathetic control and affect the power of statistical tests utilized to discriminate conditions and/or groups...
  48. ncbi Cardiac autonomic modulation during recovery from acute endurance versus resistance exercise
    Kevin S Heffernan
    Department of Kinesiology and Community Health, University of Illinois at Urbana Champaign, Exercise and Cardiovascular Research Laboratory, Champaign, IL 61820, USA
    Eur J Cardiovasc Prev Rehabil 13:80-6. 2006
    ..The kinetics of parasympathetic reactivation after dynamic endurance exercise have been well elucidated. However, autonomic recovery of cardiac function after resistance exercise is not known...
  49. pmc Cortical regions associated with autonomic cardiovascular regulation during lower body negative pressure in humans
    Derek S Kimmerly
    Neurovascular Research Laboratory, Faculty of Health Sciences and School of Kinesiology, The University of Western Ontario, London, Ontario, Canada
    J Physiol 569:331-45. 2005
    ..In addition, we have provided the first evidence for the identification of the cortical network involved specifically with baroreflex-mediated autonomic cardiovascular function in conscious humans...
  50. ncbi Developmental changes in autonomic nervous system resting and reactivity measures in Latino children from 6 to 60 months of age
    Abbey Alkon
    Department of Family Health Care Nursing, School of Nursing, University of California, San Francisco, USA
    J Dev Behav Pediatr 32:668-77. 2011
    This study describes the developmental changes and individual stability in autonomic nervous system (ANS) resting and challenge responses for a cohort of primarily Latino, low-income children during the first 5 years of life.
  51. ncbi Impairment of autonomic nervous system activity in patients with pulmonary arterial hypertension: a case control study
    Stavros Dimopoulos
    3rd Cardiology Department, NKUA, Athens, Greece
    J Card Fail 15:882-9. 2009
    ..The aim of this study was to evaluate CR and HRR in patients with pulmonary arterial hypertension (PAH) in relation to disease severity...
  52. ncbi Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study
    E J Brunner
    International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, England
    Circulation 106:2659-65. 2002
    ..We examine reversibility and the power of psychosocial and behavioral factors to explain the neuroendocrine adaptations that accompany MS...
  53. pmc Distal sudomotor findings in postural tachycardia syndrome
    Amanda Catherine Peltier
    Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, USA
    Clin Auton Res 20:93-9. 2010
    ..Norepinephrine levels above 600 pg/ml have also been used to delineate patients with a hyperadrenergic state. This study aims to determine the relationship of sudomotor abnormalities to other aspects of dysautonomia in POTS...
  54. pmc Autonomic nervous system activity measured directly and QT interval variability in normal and pacing-induced tachycardia heart failure dogs
    Gianfranco Piccirillo
    Dipartimento di Scienze dell Invecchiamento, Universita degli Studi di Roma La Sapienza, Rome, Italy
    J Am Coll Cardiol 54:840-50. 2009
    ..This study sought to find out more about the relationship between sympathetic and vagal nerve activity and the cardiac repolarization in a canine model of pacing-induced tachycardia congestive heart failure (CHF)...
  55. ncbi Immediate effect of slow pace bhastrika pranayama on blood pressure and heart rate
    Tapas Pramanik
    Department of Physiology, Nepal Medical College, Kathmandu, Nepal
    J Altern Complement Med 15:293-5. 2009
    ....
  56. ncbi The autonomic nervous system and inflammatory bowel disease
    Cormac T Taylor
    School of Medicine and Medical Science, UCD Conway Institute, University College Dublin, Ireland
    Auton Neurosci 133:104-14. 2007
    ..The autonomic nervous system (ANS) has long been known as a critical regulator of intestinal function and much evidence now exists to ..
  57. ncbi Cardiovascular stress hyperreactivity in babies of smokers and in babies born preterm
    Gary Cohen
    Department of Women and Child Health, Neonatal Unit, Karolinska Institute, Elevhemmet H1 02, S 171 76 Stockholm, Sweden
    Circulation 118:1848-53. 2008
    ..Here, we used 2 routine stress reactivity tests to identify incipient "silent" programming of cardiovascular dysfunction associated with adverse perinatal events...
  58. ncbi Love: an emergent property of the mammalian autonomic nervous system
    S W Porges
    Institute for Child Study, University of Maryland, College Park 20742 1131, USA
    Psychoneuroendocrinology 23:837-61. 1998
    The evolution of the autonomic nervous system provides an organizing principle to interpret the adaptive significance of mammalian affective processes including courting, sexual arousal, copulation, and the establishment of enduring ..
  59. ncbi Evidence for autonomic nervous system dysfunction in females with idiopathic overactive bladder syndrome
    Katelyne Hubeaux
    Faculte de Medecine, Universite Pierre et Marie Curie, ER 6, Paris, France
    Neurourol Urodyn 30:1467-72. 2011
    Micturition and continence are largely under the control of the autonomic nervous system (ANS)...
  60. ncbi Heart rate variability and cardiac reflexes in small for gestational age infants
    Barbara C Galland
    Dept of Women s and Children s Health, Dunedin School of Medicine, Univ of Otago, PO Box 913, Dunedin, New Zealand
    J Appl Physiol (1985) 100:933-9. 2006
    ..The finding that the sympathetic component of the control of HRV was higher in SGA infants could link with findings in adulthood of an association between being born SGA and a higher risk of cardiovascular disease...
  61. ncbi Increase in the vagal modulation by acupuncture at neiguan point in the healthy subjects
    Sheng Teng Huang
    Department of Chinese Medicine, Chang Gung Memorial Hospital, Kaohsiung, Taiwan
    Am J Chin Med 33:157-64. 2005
    ..This result may be helpful in the understanding of the mechanism underlying the effect of acupuncture or acupressure at P6 on the lessening of nausea and vomiting in clinic...
  62. ncbi Activation of peripheral delta2 opioid receptors increases cardiac tolerance to ischemia/reperfusion injury Involvement of protein kinase C, NO-synthase, KATP channels and the autonomic nervous system
    Leonid N Maslov
    Laboratory of Experimental Cardiology, Research Institute of Cardiology, Siberian Branch, Russian Academy of Medical Sciences, Tomsk, Russia
    Life Sci 84:657-63. 2009
    ..to investigate the role of peripheral delta(2) opioid receptors in cardiac tolerance to ischemia/reperfusion injury and to examine the contribution of PKC, TK, K(ATP) channels and the autonomic nervous system in delta(2) cardioprotection.
  63. ncbi Periodic variation in R-R intervals and cardiovascular autonomic regulation in young adult Syrian hamsters
    H Mongue-Din
    Institut de Myologie INSERM, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Am J Physiol Regul Integr Comp Physiol 296:R610-7. 2009
    ..Therefore, Syrian hamsters represent a unique model for HRV studies...
  64. ncbi Short-term autonomic and cardiovascular effects of mindfulness body scan meditation
    Blaine Ditto
    Department of Psychology, McGill University, Montreal, QC, Canada
    Ann Behav Med 32:227-34. 2006
    ..Recent research suggests that the Mindfulness-Based Stress Reduction program has positive effects on health, but little is known about the immediate physiological effects of different components of the program...
  65. ncbi The chronic fatigue syndrome is a disease of the autonomic nervous system. Sometimes
    Roy Freeman
    Clin Auton Res 12:231-3. 2002
  66. ncbi Cardiovascular autonomic nervous system tests: determination of normative values and effect of confounding variables
    D A Gelber
    Department of Neurology, Southern Illinois University School of Medicine, Springfield 62794 9230, USA
    J Auton Nerv Syst 62:40-4. 1997
    ....
  67. ncbi Clinical implications of present physiological understanding of HRV components
    Federico Lombardi
    Cardiologia, Dipartimento di Medicina Chirurgia e Odontoiatria, Osp San Paolo, University of Milan, Milan, Italy
    Card Electrophysiol Rev 6:245-9. 2002
    ....
  68. ncbi Is there a glycemic threshold for impaired autonomic control?
    L L Watkins
    Department of Psychiatry and Behavioral Sciences, Duke University, Durham, North Carolina 27710, USA
    Diabetes Care 23:826-30. 2000
    ..This study examined whether fasting plasma glucose (FPG) or fasting plasma insulin (FPI) is associated with reductions in baroreflex sensitivity (BRS) in healthy volunteers...
  69. ncbi The autonomic and sensory innervation of the smooth muscle of the prostate gland: a review of pharmacological and histological studies
    J N Pennefather
    Department of Pharmacology, Monash University, Vic, Australia
    J Auton Pharmacol 20:193-206. 2000
    ..Whether drugs that mimic or modify their actions might be useful in providing symptomatic relief of the urinary symptoms associated with BPH remains to be established...
  70. ncbi Physiology of long pranayamic breathing: neural respiratory elements may provide a mechanism that explains how slow deep breathing shifts the autonomic nervous system
    Ravinder Jerath
    Augusta Women s Center, 2100 Central Avenue, Suite 6 and 7, Augusta, GA 30904, USA
    Med Hypotheses 67:566-71. 2006
    ..It is our hypothesis that voluntary slow deep breathing functionally resets the autonomic nervous system through stretch-induced inhibitory signals and hyperpolarization currents propagated through both neural ..
  71. ncbi Frontal midline theta rhythm is correlated with cardiac autonomic activities during the performance of an attention demanding meditation procedure
    Y Kubota
    Department of Neuropsychiatry, Faculty of Medicine, Kyoto University, Shogoin Kawaharacho, 606 8507, Kyoto, Japan
    Brain Res Cogn Brain Res 11:281-7. 2001
    ..to be the generator of this activity, and the regulative function of the frontal neural network over autonomic nervous system (ANS) during cognitive process is suggested...
  72. ncbi Brain, breathing and breathlessness
    A Guz
    Charing Cross and Westminster Medical School, London, UK
    Respir Physiol 109:197-204. 1997
    ..The opportunities for further work are outlined...
  73. ncbi Effects of music therapy on autonomic nervous system activity, incidence of heart failure events, and plasma cytokine and catecholamine levels in elderly patients with cerebrovascular disease and dementia
    Kaoru Okada
    Department of Internal Medicine and Cardiology, Nippon Medical School, Tokyo, Japan
    Int Heart J 50:95-110. 2009
    ..We investigated the effects of MT on the autonomic nervous system and plasma cytokine and catecholamine levels in elderly patients with CVD and dementia, since these are ..
  74. pmc Analysis of cardiac autonomic modulation in obese and eutrophic children
    Luiz Carlos Marques Vanderlei
    Departament of Physiotherapy, School of Science and Technology, Univ Estadual Paulista, Presidente Prudente, SP, Brazil
    Clinics (Sao Paulo) 65:789-92. 2010
    ..Obesity causes alterations in cardiac autonomic function. However, there are scarce and conflicting data on this function with regard to heart rate variability in obese children...
  75. pmc Central and autonomic nervous system interaction is altered by short-term meditation
    Yi Yuan Tang
    Institute of Neuroinformatics and Laboratory for Body and Mind, Dalian University of Technology, Dalian 116024, China
    Proc Natl Acad Sci U S A 106:8865-70. 2009
    ..Differences in heart rate variability (HRV) and EEG power suggested greater involvement of the autonomic nervous system (ANS) in the IBMT group during and after training...
  76. ncbi Triggered firing in pulmonary veins initiated by in vitro autonomic nerve stimulation
    Eugene Patterson
    University of Oklahoma Health Sciences Center and Department of Veterans Affairs Medical Center, Oklahoma City, Oklahoma, USA
    Heart Rhythm 2:624-31. 2005
    Rapid firing within pulmonary vein sleeves frequently initiates atrial fibrillation. The role of the autonomic nervous system in facilitating spontaneous firing is unknown.
  77. ncbi Reduced autonomic activity during stepwise exposure to high altitude
    K Sevre
    Department of Cardiology, , Oslo, Norway
    Acta Physiol Scand 173:409-17. 2001
    ..1 +/- 6%, P = 0.03). Diastolic blood pressure, HR and adrenaline displayed similar tendencies. We conclude that a transient reduction in parasympathetic and sympathetic activity was demonstrated during stepwise exposure to high altitude...
  78. ncbi Circadian profile of cardiac autonomic nervous modulation in healthy subjects: differing effects of aging and gender on heart rate variability
    Hendrik Bonnemeier
    Medizinische Kinik II, Medizinische Universitat zu Lubeck, Lubeck, Germany
    J Cardiovasc Electrophysiol 14:791-9. 2003
    ..Circadian Profile of Heart Rate Variability...
  79. ncbi Point: cardiovascular variability is/is not an index of autonomic control of circulation
    Gianfranco Parati
    Department of Clinical Medicine Prevention and Applied Biotechnology University of Milano Bicocca Milan, Italy
    J Appl Physiol 101:676-8; discussion 681-2. 2006
  80. ncbi Cognitive influences on human autonomic nervous system function
    K Hugdahl
    Department of Biological and Medical Psychology, University of Bergen, Norway
    Curr Opin Neurobiol 6:252-8. 1996
    Recent studies of human autonomic nervous system function have challenged the traditional view that the parasympathetic and sympathetic branches have opposite effects...
  81. ncbi Trait negative affect: toward an integrated model of understanding psychological risk for impairment in cardiac autonomic function
    Maria E Bleil
    Department of Psychiatry, University of California San Francisco, 3333 California Street, Suite 465, San Francisco, CA 94143 0848, USA
    Psychosom Med 70:328-37. 2008
    ..g., autonomic nervous system [ANS] dysfunction), the degree to which a general tendency to experience negative emotions may account ..
  82. ncbi Interoception: the sense of the physiological condition of the body
    A D Craig
    Atkinson Pain Research Laboratory, Division of Neurosurgery, Barrow Neurological Institute, Phoenix, AZ 85013, USA
    Curr Opin Neurobiol 13:500-5. 2003
    ....
  83. ncbi Growth of the rat prostate gland is facilitated by the autonomic nervous system
    K T McVary
    Department of Urology, Northwestern University Medical School, Chicago, Illinois 60611
    Biol Reprod 51:99-107. 1994
    ..This study examines the role of the sympathetic and parasympathetic branches of the autonomic nervous system control of different aspects of rat prostate growth and atrophy...
  84. pmc Cerebral correlates of autonomic cardiovascular arousal: a functional neuroimaging investigation in humans
    H D Critchley
    Wellcome Department of Cognitive Neurology, Institute of Neurology and Autonomic Unit, National Hospital for Neurology and Neurosurgery, Institute of Neurology, University College London, Queen Square, London, UK
    J Physiol 523:259-70. 2000
    ....
  85. pmc Effects of prior intensive insulin therapy on cardiac autonomic nervous system function in type 1 diabetes mellitus: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study (DCCT/EDIC)
    Rodica Pop-Busui
    University of Michigan, Department of Internal Medicine, Division of Metabolism, Endocrinology, Diabetes, Ann Arbor, MI, USA
    Circulation 119:2886-93. 2009
    ..We evaluated the effects of prior intensive insulin therapy on the prevalence and incidence of cardiac autonomic neuropathy (CAN) in former DCCT intensive and conventional therapy subjects 13 to 14 years after DCCT closeout...
  86. pmc Projections from bed nuclei of the stria terminalis, anteromedial area: cerebral hemisphere integration of neuroendocrine, autonomic, and behavioral aspects of energy balance
    Hong Wei Dong
    Department of Biological Sciences, University of Southern California, Los Angeles, 90089 2520, USA
    J Comp Neurol 494:142-78. 2006
    ....
  87. ncbi Heart rate variability: a noninvasive electrocardiographic method to measure the autonomic nervous system
    Juan Sztajzel
    Cardiology Center and Medical Policlinics, University Hospital, Geneva, Switzerland
    Swiss Med Wkly 134:514-22. 2004
    The autonomic nervous system (ANS) plays an important role not only in physiological situations, but also in various pathological settings such as diabetic neuropathy, myocardial infarction (MI) and congestive heart failure (CHF)...
  88. ncbi Autonomy of autonomic dysfunction in major depression
    Mandy Koschke
    Department of Psychiatry and Psychotherapy, University Hospital Jena, 07743 Jena, Germany
    Psychosom Med 71:852-60. 2009
    ..Research in this area has faced several limitations because of the heterogeneity of the disease, the influence of medication, and methodological shortcomings...
  89. pmc Cardiovascular autonomic neuropathy, HDL cholesterol, and smoking correlate with arterial stiffness markers determined 18 years later in type 1 diabetes
    Catherine T Prince
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes Care 33:652-7. 2010
    ..This association persists after adjustment for potential confounders as well as for baseline HbA(1), HDL cholesterol, and smoking history, which were also associated with these PWA measures...
  90. ncbi Responses to laboratory psychosocial stress in postpartum women
    M Altemus
    Department of Psychiatry, Weill Medical College, Cornell University, New York, NY 10021, USA
    Psychosom Med 63:814-21. 2001
    ..This study was designed to determine the effect of lactation on hypothalamic-pituitary-adrenal axis, autonomic nervous system, and anxiety responses to psychological stress.
  91. pmc The polyvagal theory: new insights into adaptive reactions of the autonomic nervous system
    Stephen W Porges
    Brain Body Center, Department of Psychiatry MC 912, 1601 W Taylor Street, Chicago, IL 60612, USA
    Cleve Clin J Med 76:S86-90. 2009
    The polyvagal theory describes an autonomic nervous system that is influenced by the central nervous system, sensitive to afferent influences, characterized by an adaptive reactivity dependent on the phylogeny of the neural circuits, and ..
  92. ncbi Plasma leptin concentrations and cardiac autonomic nervous system in healthy subjects with different body weights
    G Paolisso
    Department of Geriatric Medicine and Metabolic Diseases II, University of Naples, Italy
    J Clin Endocrinol Metab 85:1810-4. 2000
    ....
  93. ncbi The biological clock tunes the organs of the body: timing by hormones and the autonomic nervous system
    R M Buijs
    Netherlands Institute for Brain Research, Meibergdreef 33, 1105 AZ Amsterdam, The Netherlands
    J Endocrinol 177:17-26. 2003
    ..of the hypothalamus (PVN) is crucial for the organization/synchronization of the neuroendocrine and autonomic nervous system with the time of day. This SCN-neuroendocrine PVN axis takes care of a timely hormonal secretion...
  94. ncbi New perspectives on the role of autonomic nervous system in the genesis of arrhythmias
    Lan S Chen
    Division of Neurology, Department of Pediatrics, Childrens Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, California 90027, USA
    J Cardiovasc Electrophysiol 18:123-7. 2007
    ..The coexistence of denervated and hyperinnervated area in the diseased myocardium could result in increased electrophysiological heterogeneity during sympathetic activation, leading to ventricular arrhythmia and SCD...
  95. ncbi The expression pattern of the transcription factor Phox2 delineates synaptic pathways of the autonomic nervous system
    M C Tiveron
    Institut de Biologie du Developpement de Marseille, Centre National dela Recherche Scientifique Institut National de la Santé et de la Recherche Médicale Université de la Mediterranée, Marseille, France
    J Neurosci 16:7649-60. 1996
    ..e., that of the medullary control reflexes of autonomic functions. This suggests that Phox2 could be involved in the establishment of these circuits...
  96. pmc The effect of aerobic training and cardiac autonomic regulation in young adults
    Richard P Sloan
    Division of Behavioral Medicine, Department of Psychiatry, Columbia University, 1150 St Nicholas Ave, Suite 121, New York, NY 10032, USA
    Am J Public Health 99:921-8. 2009
    ..We tested the effect of aerobic exercise on autonomic regulation of the heart in healthy young adults...
  97. ncbi The autonomic nerve supply of male sex organs--an important target of circulating androgens
    J R Keast
    Department of Physiology and Pharmacology, University of Queensland, Australia
    Behav Brain Res 105:81-92. 1999
    The autonomic nervous system plays a critical role in the regulation of smooth muscle contraction, exocrine secretion and blood flow in the male reproductive organs...
  98. ncbi HoxB8 in noradrenergic specification and differentiation of the autonomic nervous system
    Leslie Huber
    Research Group Developmental Neurobiology, Max Planck Institute for Brain Research, Frankfurt Main, Germany
    Dev Biol 363:219-33. 2012
    ..These results implicate that Hox genes contribute to the differential development of autonomic neuron precursors by maintaining noradrenergic properties in the trunk sympathetic neuron lineage...
  99. ncbi Power spectral analysis of heart rate variability in HIV-infected and AIDS patients
    Dalmo Correia
    Infectious Diseases Division, Department of Internal Medicine, School of Medicine of the Triangulo Mineiro, Uberaba, MG, Brazil
    Pacing Clin Electrophysiol 29:53-8. 2006
    ..In HIV-infected patients the risks for cardiovascular disease are multifactorial. Autonomic dysfunction has been detected in the early phase of HIV infection as well as in AIDS patients with advanced cardiomyopathy...
  100. pmc Autonomic circulatory control during pregnancy in humans
    Qi Fu
    Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, Dallas, TX 75231, USA
    Semin Reprod Med 27:330-7. 2009
    ..been proposed that these changes occur through autonomic control mechanisms, but the actual role of the autonomic nervous system in pregnancy is poorly understood...
  101. ncbi Cardiac autonomic nervous system activity in obesity
    Stavros Liatis
    1st Department of Propaedeutic Medicine, Athens University Medical School, Laiko General Hospital, Athens, Greece
    Pediatr Endocrinol Rev 1:476-83. 2004
    ..As the autonomic nervous system (ANS) has a role in the regulation of both these variables, it has become a major focus of investigation ..

Research Grants71

  1. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
    ..abstract_text> ..
  2. Autonomic, Endothelial, and Inflammatory Correlates of Sleep Duration
    MERCEDES RENEE CARNETHON; Fiscal Year: 2012
    ..Pathophysiologic mechanisms that could explain these associations such as autonomic nervous system dysfunction, endothelial dysfunction, inflammation, and insulin resistance have been identified in the ..
  3. Chronic nicotine and synaptic transmission in brainstem respiratory neurons
    RALPH FRANK FREGOSI; Fiscal Year: 2013
    ..women smoke, and their offspring have a higher than normal incidence of impaired cardiac function, autonomic nervous system disorders, sleep disorders, delayed speech and central and obstructive apneas...
  4. Respiratory and autonomic plasticity following intermittent hypoxia
    JASON HAROLD MATEIKA; Fiscal Year: 2012
    ..e. a change in system performance based on prior experience) of the respiratory and autonomic nervous system. One adaptation that has been shown to manifest itself in animals following exposure to IH is long-term ..
  5. Iyengar yoga for adolescents and young adults with irritable bowel syndrome
    Subhadra Evans; Fiscal Year: 2013
    ..and include the mediating effects of visceral sensitivity, increased psychospiritual resources, regulated autonomic nervous system (ANS) responses (measured in response to the visceral sensitivity task) and regulated hormonal stress ..
  6. Respiratory motor control and blood pressure regulation after spinal cord injury
    ALEXANDER VLADIMIROVICH OVECHKIN; Fiscal Year: 2013
    ..blood pressure which frequently results in persistent hypotension due to decreased cardiac output and autonomic nervous system dysfunction...
  7. Race-based social stress and health trajectories from adolescence to adulthood
    Jacquelynne S Eccles; Fiscal Year: 2010
    ..e., hypothalamic-pituitary-adrenal [HPA] axis, autonomic nervous system, inflammatory system) in the context of a daily diary study and also in an experimental setting in which ..
  8. Disruption of Autonomic Pathways in Left Atrium by Inhibition of G Proteins
    Alan H Kadish; Fiscal Year: 2010
    ..The autonomic nervous system regulates critical cardiac parameters such as excitability, heart rate, force of contraction, conduction ..
  9. Depression, Adipocytokines and Metabolic Dysregulation in Black and White Women
    Susan A Everson Rose; Fiscal Year: 2010
    ..a pro-inflammatory adipocytokine intimately involved in regulation of metabolism, energy balance, and autonomic nervous system functioning...
  10. Remodeling of the guinea pig intrinsic cardiac plexus with chronic heart disease
    ELIZABETH MARIE SOUTHERLAND; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE: This proposal will examine how the autonomic nervous system adapts to chronic heart disease, with the goal of developing better therapeutics for the treatment of ..
  11. Sympathetic Regulation of AMPK in the control of non-shivering thermogenesis
    Jacob D Mulligan; Fiscal Year: 2012
    ..Our studies examine a way of metabolizing calories into heat instead of storing them as fat, and the possibility that the "health" of fat is regulated by a branch of the autonomic nervous system.
  12. Prenatal stress and epigenetic programming of the HPA axis and autonomic balance
    Rosalind J Wright; Fiscal Year: 2013
    ..stress responses in the offspring including the hypothalamic-pituitary adrenal (HPA) axis and autonomic nervous system (ANS) functioning which may have long-term implications on health...
  13. Perinatal Assessment of At-Risk Populations
    William P Fifer; Fiscal Year: 2013
    ..more direct measures of CNS maturation during sleep, as well as more sophisticated analyses of autonomic nervous system regulation in both the fetus and infant in healthy and at-risk populations...
  14. Disruption of Autonomic Pathways in the Left Atrium by Inhibition of G-proteins
    Rishi Arora; Fiscal Year: 2013
    ..The autonomic nervous system regulates critical cardiac parameters such as excitability, heart rate, force of contraction, conduction ..
  15. Environmental Triggers of Cardiometabolic Disease
    Sanjay Rajagopalan; Fiscal Year: 2013
    ..5 levels and alterations in (a) adipocytokines/inflammatory variables and autonomic nervous system (ANS) balance...
  16. Stress and Subclinical Cardio-Metabolic Disease in Police: A Longitudinal Study
    John M Violanti; Fiscal Year: 2013
    ..blood pressure;laboratory measurement of lipids, glucose, and insulin;heart rate variability to assess autonomic nervous system function;ultrasound imaging studies to measure carotid artery wall thickness (atherosclerosis) and ..
  17. Sex Differences in Myocardial Ischemia Triggered by Emotional Factors after MI
    Viola Vaccarino; Fiscal Year: 2010
    ..stress, including differences in hemodynamic (blood pressure, heart rate), neurobiological (cortisol and autonomic nervous system) and inflammatory responses to the stressful challenge...
  18. Chronic stress-induced gene expression in colonic circular smooth muscle cells.
    Sushil K Sarna; Fiscal Year: 2012
    ..are: corticotropin releasing hormone, norepinephrine, glucocorticoids and the neurotransmitters of the autonomic nervous system. The inflammatory response is mediated by cytokines, chemokines and cell adhesion molecules...
  19. Melanocortin-4 Receptor-dependent regulation of energy balance after gastric bypa
    Vincent Aguirre; Fiscal Year: 2013
    ..The MC4R is expressed in structures of the autonomic nervous system (ANS) that are involved in the regulation of body weight and glucose metabolism (which is dysregulated in ..
  20. Mechanisms of Meditation in Hypertension in Blacks
    Robert Schneider; Fiscal Year: 2010
    ..objective of this study is to investigate acute and chronic effects of meditation on cardiovascular and autonomic nervous system mechanisms of high blood pressure in this high-risk minority population...
  21. NEUROBIOLOGY OF VARICELLA ZOSTER VIRUS
    Donald Gilden; Fiscal Year: 2013
    ..virus (VZV) causes chickenpox, after which the virus becomes latent in cranial nerve, dorsal root and autonomic nervous system ganglia along the entire neuraxis...
  22. Hostility, PTSD and Physical Health Risk Factors
    Jean C Beckham; Fiscal Year: 2013
    ..and blood pressure recovery to a stressful task is slower in hostile veterans with PTSD suggest that the autonomic nervous system may be involved in the increased risk in PTSD veterans with high hostility...
  23. Sympathetic Nervous System and Heart Failure-Role of Primary Afferent Neurons
    Jianhua Li; Fiscal Year: 2010
    ..The long-term goals of the PI are to better understand the mechanisms that regulate the autonomic nervous system during exercise in HF...
  24. Prenatal diet, PM2.5 and programming of the infant autonomic response
    Rosalind J Wright; Fiscal Year: 2013
    ..The autonomic nervous system (ANS) is a putative key regulatory system vulnerable to perinatal environmental programming toward ..
  25. Gender differences in aortic baroreceptor function and neural integration
    John H Schild; Fiscal Year: 2013
    ..important factors, but clinical studies are revealing potential gender differences in afferent mediated autonomic nervous system (ANS) function. Some ANS assessments of cardiovagal reflexes have proven to be sexually dimorphic...
  26. Epidemiologic Studies of Type 2 Diabetes in Normal Weight Adults
    MERCEDES RENEE CARNETHON; Fiscal Year: 2010
    ..e., inflammation, autonomic nervous system function, and depressive symptoms) are predictors of disease in the absence of obesity...
  27. A Prospective Cohort Study of Migraines, Platelet Activation, and Preeclampsia
    Michelle A Williams; Fiscal Year: 2012
    ..common chronic-episodic disorder of idiopathic origin characterized by severe debilitating headaches and autonomic nervous system dysfunction, often accompanied by neurological symptoms, and distinguished from tension-type headaches by ..
  28. Mechanisms of Neuroprotection in the Nucleus Tractus Solitarius of Hibernators
    BARBARA ANN HORWITZ; Fiscal Year: 2010
    ..The long-term goals of the PI are to better understand the mechanisms that regulate the autonomic nervous system during exercise in HF...
  29. Factors that Initiate Arrhythamias in Long QT Syndrome
    Guy Salama; Fiscal Year: 2006
    DESCRIPTION (provided by applicant): The role of the autonomic nervous system in the genesis of life-threatening arrhythmias has been the subject of intense investigation yet remains incomplete and fragmented...
  30. Modulation of Hepatocellular Function in Sepsis
    Ping Wang; Fiscal Year: 2013
    ..The autonomic nervous system reflexively regulates inflammatory responses in real time...
  31. Neuroendocrine Regulation of Adipocyte Metabolism
    Diego Perez-Tilve; Fiscal Year: 2013
    ..we will test if those CNS melanocortin receptors employ downstream neuropeptides CRH/TRH and the efferent autonomic nervous system axis to control cellular lipid metabolism in liver and adipose tissue...
  32. Radiation Combined Injury: Mechanisms and Therapeutic Approaches
    Ping Wang; Fiscal Year: 2012
    ..improves survival;and 3) conduct feasibility experiments demonstrating the effect of human ghrelin on the autonomic nervous system after radiation combined injury...
  33. From Child Maltreatment to Adolescent Substance Abuse: Risks, Protective Factors
    Penelope K Trickett; Fiscal Year: 2010
    ..indictors of stress reactivity (salivary cortisol and salivary alpha amylase) and autonomic nervous system arousal (skin conductance, heart rate);indicators of cognitive abilities and school performance;and ..
  34. Physiological and Emotional Reactivity to Pain after Physical and Sexual Abuse
    KARIN N WESTLUND-HIGH; Fiscal Year: 2011
    ..Hypothesis: Improved self-regulation of autonomic nervous system function with controlled breathing can offset altered physiological responses to a painful heat stress ..
  35. Paraventricular Nucleus Signaling Mechanisms in Hypertension
    Carrie A Northcott; Fiscal Year: 2010
    ..of metabolic processes, stress responses, cardiovascular function/blood pressure regulation and the autonomic nervous system. The overall hypothesis is that sodium-dependent hypertension is associated with increased excitatory ..
  36. The Effects of Docosahexaenoic acid (DHA) on fetal cardiac outcomes
    Kathleen M Gustafson; Fiscal Year: 2010
    ..maternal red blood cell phospholipid DHA and thus will have a positive influence on fetal cardiac autonomic nervous system regulation reflected in higher vagal control (reduced HR) and increased HRV...
  37. Inter-Parental Conflict, Maternal Behavior, and Mother-Child Physiology
    LEAH CORINNE HIBEL; Fiscal Year: 2012
    ..components of the psychobiology of the stress response (the hypothalamic pituitary adrenal axis and the autonomic nervous system, respectively)...
  38. Integrative Stress Reduction for Maternal-Child Health
    Larissa G Duncan; Fiscal Year: 2013
    ..on psychological stress and coping mechanisms, stress physiology (neuroendocrine and cardiovascular/ autonomic nervous system function), and birth outcomes (gestational age and birth weight) will be compared...
  39. Anesthesiology Research Training Program
    Judy R Kersten; Fiscal Year: 2013
    ..cell physiology, adhesion molecules, eicosanoids, exercise and respiratory physiology, hypertension, autonomic nervous system, nitric oxide synthase, nociception, chronic pain, cardioprotection, cerebral circulation)...
  40. Leptin in Human Energy and Neuroendocrine Homeostasis
    Rudolph L Leibel; Fiscal Year: 2013
    ..quantitative studies of body composition, compartmentalized energy expenditure ingestive behavior, autonomic nervous system activity, regional neuronal activity related to energy intake by fMRI, chemical analysis of CSF for ..
  41. Pupil Size and Circadian Salivary Variations in Autism Spectrum Disorder
    JOHN A COLOMBO; Fiscal Year: 2010
    ..Both the hypothalamic and norepinephrine systems contribute to the control of the autonomic nervous system and help to maintain appropriate levels of alertness to prepare the CNS to respond to incoming ..
  42. Nicotinic acetylcholine receptors and neuroblastoma
    Rae Nishi; Fiscal Year: 2012
    ..and therefore may be a new target for drugs because these receptors are uncommon in the normal autonomic nervous system. The proposed aims will test this hypothesis by: 1) using RNAi to determine whether one or more nAChR ..
  43. Treatment of Cocaine Addiction with Integrative Meditation
    Kevin W Chen; Fiscal Year: 2010
    ..to aid in understanding possible underlying mechanisms of IM's effect on attention networks and the autonomic nervous system. A diverse team experienced in meditation and behavior therapy development is brought together to conduct ..
  44. Intermittent Hypoxia: A Model to Study Circulatory Control in Humans
    Urs A Leuenberger; Fiscal Year: 2012
    ..ischemia) exert their effects on the circulation via integrated but at times opposing influences on the autonomic nervous system and local metabolic control...
  45. AUTONOMIC CARDIOVASCULAR REGULATION
    DAVID HERLIE ROBERTSON; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The autonomic nervous system is the crucial link between the brain and the cardiovascular system...
  46. The role of innervation for hormone secretion in human islets
    ALEJANDRO CAICEDO VIERKANT; Fiscal Year: 2013
    ..The central hypothesis is that the autonomic nervous system modulates human islet function by regulating blood flow within the islet...
  47. Glial Modulation of Autonomic Nervous System Activity
    KEN DOUGLAS MCCARTHY; Fiscal Year: 2013
    ..and piloerection, and a decrease in body temperature;each of these parameters are regulated by the autonomic nervous system. Importantly, CNO has no effect in littermate wt mice, and astrocytic Gq-DREADD mice are not different ..
  48. The role of innervation for hormone secretion in human islets
    ALEJANDRO CAICEDO VIERKANT; Fiscal Year: 2009
    ..The central hypothesis is that in mouse islets the autonomic nervous system modulates insulin secretion via parasympathetic cholinergic fibers and glucagon secretion via sympathetic ..
  49. The Impact of Stress and Psychosocial Factors on Inflammation in Women
    Susan A Everson-Rose; Fiscal Year: 2012
    ..is a pro-inflammatory adipocytokine intimately involved in metabolic regulation, energy balance, and autonomic nervous system functioning...
  50. Detection and Alerting System for Seizure Onset (DASSO)
    Todd A Summers; Fiscal Year: 2013
    ..development and testing of feature extraction and statistical change detection methodologies that exploit autonomic nervous system (ANS) activations preceding or concomitant with seizure events...
  51. The Treatment of Depression with Yoga and Walking
    CHRIS CONWAY STREETER; Fiscal Year: 2013
    ..Changes in neurochemistry, autonomic nervous system function and mood states associated with the interventions will be measured in both interventions over a ..
  52. Hypothalamic Neuronal Plasticity in Chronic Stress
    De Pei Li; Fiscal Year: 2013
    ..populations involved in the regulation of the hypothalamic-pituitary-adrenocortical (HPA) axis and autonomic nervous system. Stimulation of corticotrophin-releasing hormone (CRH)-expressing parvocellular neurons increases ..
  53. FETAL CARDIOVASCULAR AND ENDOCRINE REFLEX RESPONSES
    Charles E Wood; Fiscal Year: 2013
    ..the renewal of this project: 1) to test the hypothesis that ACTH and Arginine Vasopressin (AVP), but not autonomic nervous system responses to BCO, isocapnic hypoxic hypoxia (HH), and partial umbilical cord occlusion (UCC) are ..
  54. A NURSING STUDY OF GUT FUNCTION IN MENSTRUATING WOMEN
    Margaret McLean Heitkemper; Fiscal Year: 2013
    ..Psychological distress, the autonomic nervous system and serotonin transporter protein polymorphisms may serve as biomarkers of symptom type and severity in ..
  55. Social and psychological risk for infectious illness
    Sheldon A Cohen; Fiscal Year: 2010
    ..that the social environment influences behavior, hypothalamic-pituitary-adrenocortical (HPA) and autonomic nervous system (ANS) responses which in turn influence the regulation of both cellular and humoral immune response to ..
  56. Cardiac dysfunction in epilepsy: a candidate mechanism in sudden unexpected death
    Anne E Anderson; Fiscal Year: 2012
    ..Imbalance in the autonomic nervous system, specifically sympathetic nervous system activity is considered an important player in the development of ..
  57. Cardiovascular Regulation in Hindlimb Unweighted Rats
    Eileen M Hasser; Fiscal Year: 2010
    ..bedrest or microgravity, and in rats after HU, are not clear, but alterations in regulation of the autonomic nervous system likely play an important role Blunted sympathetic vasoconstriction and enhanced cardiopulmonary receptor ..
  58. Peripheral and Central Mechanisms of Fatigue and Pain in Patients with ME/CFS
    Roland Staud; Fiscal Year: 2013
    ..ERGO) (afferents sensitive to muscle metabolites) and nociceptors in muscles with resulting autonomic nervous system (ANS), HPAaxis, fatigue, and pain pathway activation...
  59. Regulation of adipose tissue metabolism by central insulin and leptin
    Christoph Buettner; Fiscal Year: 2013
    ..The brain control of adipose tissue metabolism via the autonomic nervous system is poorly understood...
  60. Regulation and Function of Ascl1 in Neural Development
    Jane E Johnson; Fiscal Year: 2013
    ..and sub- type specification of multiple neuronal cell-types throughout the brain, spinal cord, and autonomic nervous system, as well as neuroendocrine cels and cels in sensory systems such as the retina and olfactory epithelia...
  61. Diabetes suppresses sympathetic neurotransmission and thereby glucagon secretion
    Gerald J Taborsky; Fiscal Year: 2013
    ..of the glucagon response to both moderate and marked insulin-induced hypoglycemia is mediated by the autonomic nervous system. This autonomic activation is caused by central neuroglucopenia and includes activation of pancreatic ..
  62. Hypothalamic and Limbic Forebrain Stress Reactivity
    Layla Banihashemi; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): In response to an acute stressor, the autonomic nervous system orchestrates a number of cardiovascular adjustments, including increases in blood pressure and heart rate, which support an adaptive ..
  63. Neuroendocrine Mechanisms of Developmental Massage Therapy in Preterm Infants
    Laurie Moyer Mileur; Fiscal Year: 2009
    ..Physiologic stability is dependent upon the sympathetic (SNS) and parasympathetic (PNS) branches of the autonomic nervous system (ANS) and the hypothalamic-pituitary-adrenal (HPA) axis of the endocrine system...
  64. BAROREFLEX AND POSTERIOR HYPOTHALAMIC NEUROPEPTIDE-Y
    John Martin; Fiscal Year: 1991
    ..The goal of Specific Aim 1 is to determine the contribution of the autonomic nervous system to the cardiovascular changes elicited by posterior hypothalamic administration of NPY or carbachol (CCH)...
  65. Autonomic consequences of brief seizures
    Mark Stewart; Fiscal Year: 2004
    Focal and generalized seizures can influence autonomic nervous system (ANS) function. Flushing, sweating and piloerection are reported in some patients with simple partial seizures...
  66. AUTONOMIC CONTROL OF LACRIMAL GLAND FUNCTION
    BARRY BROMBERG; Fiscal Year: 1980
    This project seeks to determine the function of the autonomic nervous system in the maintenance of lacrimal gland structure and in the secretion of lacrimal gland proteins...
  67. "Innate intestinal responses in murine toxoplasmosis"
    Fernando Monroy; Fiscal Year: 2005
    ..is mediated, in part, through products of the hypothalamic-pituitary-adrenal (HPA) axis and the autonomic nervous system. Stress activates the HPA axis and the sympathetic nervous system leading to the release of ..
  68. Genetic Characterization of Essential Hyperhidrosis
    Gary Swergold; Fiscal Year: 2003
    ..Hyperhidrosis (EH), and to develop an improved understanding of the regulation of sweating by the autonomic nervous system. EH is a relatively common disorder in which patients' experience excessive sweating from their palms and ..
  69. SPLANCHNIC HEMODYNAMICS IN PORTAL HYPERTENSION
    JAMES SITZMANN; Fiscal Year: 1992
    ..Part I will study whether PGI2 mediates or modulates the portal hemodynamic effects of the autonomic nervous system by utilizing selective blockade and stimulation of various limbs of the autonomic nervous system in the ..
  70. Integration by Airway Parasympathic Ganglia Neurons
    Allen Myers; Fiscal Year: 2004
    In the airway, the autonomic nervous system controls smooth muscle tone, secretion by glands, and blood flow...
  71. AUTONOMIC NERVOUS SYSTEM FUNCTIONING IN THE HUMAN FETUS
    Lynn Groome; Fiscal Year: 1999
    ..in children, including learning disabilities, can be traced to deficits in attention and abnormalities in autonomic nervous system (ANS) functioning...