parietal lobe

Summary

Summary: Upper central part of the cerebral hemisphere.

Top Publications

  1. ncbi The precuneus: a review of its functional anatomy and behavioural correlates
    Andrea E Cavanna
    Institute of Neurology, Queen Square, London WC1N3BG, UK
    Brain 129:564-83. 2006
  2. ncbi Top-down versus bottom-up control of attention in the prefrontal and posterior parietal cortices
    Timothy J Buschman
    Picower Institute for Learning and Memory, RIKEN MIT Neuroscience Research Center, and Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Science 315:1860-2. 2007
  3. ncbi Parietal lobe contributions to episodic memory retrieval
    Anthony D Wagner
    Department of Psychology and Neurosciences Program, Stanford University, Stanford, CA, USA
    Trends Cogn Sci 9:445-53. 2005
  4. ncbi Capacity limit of visual short-term memory in human posterior parietal cortex
    J Jay Todd
    Vanderbilt Vision Research Center, Department of Psychology, Vanderbilt University, 530 Wilson Hall, Nashville, Tennessee 37203, USA
    Nature 428:751-4. 2004
  5. ncbi The activation of attentional networks
    Jin Fan
    Laboratory of Neuroimaging, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuroimage 26:471-9. 2005
  6. pmc Attention, intention, and priority in the parietal lobe
    James W Bisley
    Department of Neurobiology and Jules Stein Eye Institute, David Geffen School of Medicine, and Department of Psychology and the Brain Research Institute, University of California, Los Angeles, California 90095, USA
    Annu Rev Neurosci 33:1-21. 2010
  7. ncbi Breakdown of functional connectivity in frontoparietal networks underlies behavioral deficits in spatial neglect
    Biyu J He
    Department of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuron 53:905-18. 2007
  8. ncbi The human inferior parietal cortex: cytoarchitectonic parcellation and interindividual variability
    Svenja Caspers
    C and O Vogt Brain Research Institute, University of Dusseldorf, P O Box 10 10 07, 40001 Dusseldorf, Germany
    Neuroimage 33:430-48. 2006
  9. ncbi Parietal lobe: from action organization to intention understanding
    Leonardo Fogassi
    Dipartimento di Psicologia, Universita di Parma, Borgo Carissimi 10, 43100 Parma, Italy
    Science 308:662-7. 2005
  10. ncbi Uniquely human social cognition
    Rebecca Saxe
    Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology 46 4019, 43 Vassar St, Cambridge MA, 02138, USA
    Curr Opin Neurobiol 16:235-9. 2006

Detail Information

Publications351 found, 100 shown here

  1. ncbi The precuneus: a review of its functional anatomy and behavioural correlates
    Andrea E Cavanna
    Institute of Neurology, Queen Square, London WC1N3BG, UK
    Brain 129:564-83. 2006
    ..studies have started unravelling unexpected functional attributes for the posteromedial portion of the parietal lobe, the precuneus...
  2. ncbi Top-down versus bottom-up control of attention in the prefrontal and posterior parietal cortices
    Timothy J Buschman
    Picower Institute for Learning and Memory, RIKEN MIT Neuroscience Research Center, and Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Science 315:1860-2. 2007
    ..This result indicates that top-down and bottom-up signals arise from the frontal and sensory cortex, respectively, and different modes of attention may emphasize synchrony at different frequencies...
  3. ncbi Parietal lobe contributions to episodic memory retrieval
    Anthony D Wagner
    Department of Psychology and Neurosciences Program, Stanford University, Stanford, CA, USA
    Trends Cogn Sci 9:445-53. 2005
    Although the parietal lobe is not traditionally thought to support declarative memory, recent event-related fMRI studies of episodic retrieval have consistently revealed a range of memory-related influences on activation in lateral ..
  4. ncbi Capacity limit of visual short-term memory in human posterior parietal cortex
    J Jay Todd
    Vanderbilt Vision Research Center, Department of Psychology, Vanderbilt University, 530 Wilson Hall, Nashville, Tennessee 37203, USA
    Nature 428:751-4. 2004
    ..These results suggest that the posterior parietal cortex is a key neural locus of our impoverished mental representation of the visual world...
  5. ncbi The activation of attentional networks
    Jin Fan
    Laboratory of Neuroimaging, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neuroimage 26:471-9. 2005
    ..Overall, the fMRI results suggest that the functional contrasts within this single task differentially activate three separable anatomical networks related to the components of attention...
  6. pmc Attention, intention, and priority in the parietal lobe
    James W Bisley
    Department of Neurobiology and Jules Stein Eye Institute, David Geffen School of Medicine, and Department of Psychology and the Brain Research Institute, University of California, Los Angeles, California 90095, USA
    Annu Rev Neurosci 33:1-21. 2010
    For many years there has been a debate about the role of the parietal lobe in the generation of behavior...
  7. ncbi Breakdown of functional connectivity in frontoparietal networks underlies behavioral deficits in spatial neglect
    Biyu J He
    Department of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuron 53:905-18. 2007
    ..Lastly, disconnection of the white matter tracts connecting frontal and parietal cortices was associated with more severe neglect and more disrupted functional connectivity. These findings support a network view in understanding neglect...
  8. ncbi The human inferior parietal cortex: cytoarchitectonic parcellation and interindividual variability
    Svenja Caspers
    C and O Vogt Brain Research Institute, University of Dusseldorf, P O Box 10 10 07, 40001 Dusseldorf, Germany
    Neuroimage 33:430-48. 2006
    ..Furthermore, the map is registered in three dimensions and thereby provides a robust anatomical base for interpreting functional imaging studies...
  9. ncbi Parietal lobe: from action organization to intention understanding
    Leonardo Fogassi
    Dipartimento di Psicologia, Universita di Parma, Borgo Carissimi 10, 43100 Parma, Italy
    Science 308:662-7. 2005
    ..Thus, these neurons not only code the observed motor act but also allow the observer to understand the agent's intentions...
  10. ncbi Uniquely human social cognition
    Rebecca Saxe
    Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology 46 4019, 43 Vassar St, Cambridge MA, 02138, USA
    Curr Opin Neurobiol 16:235-9. 2006
    ....
  11. ncbi The role of the right temporoparietal junction in social interaction: how low-level computational processes contribute to meta-cognition
    Jean Decety
    Department of Psychology, and Center for Cognitive and Social Neuroscience, The University of Chicago, Chicago, IL 60637, USA
    Neuroscientist 13:580-93. 2007
    ..It is argued that this domain-general computational mechanism is crucial for higher level social cognitive processing...
  12. ncbi Increased activity in human visual cortex during directed attention in the absence of visual stimulation
    S Kastner
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Neuron 22:751-61. 1999
    ..The increased activity in visual cortex in the absence of visual stimulation may reflect a top-down bias of neural signals in favor of the attended location, which derives from a fronto-parietal network...
  13. ncbi People thinking about thinking people. The role of the temporo-parietal junction in "theory of mind"
    R Saxe
    Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, NE20 464, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
    Neuroimage 19:1835-42. 2003
    ..Thus, the role of the TPJ-M in understanding other people appears to be specific to reasoning about the content of mental states...
  14. ncbi Matching behavior and the representation of value in the parietal cortex
    Leo P Sugrue
    Howard Hughes Medical Institute and Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Science 304:1782-7. 2004
    ..We found that a simple model based on reward history can duplicate this behavior and that neurons in the parietal cortex represent the relative value of competing actions predicted by this model...
  15. ncbi Association fibre pathways of the brain: parallel observations from diffusion spectrum imaging and autoradiography
    Jeremy D Schmahmann
    Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston MA 02114, USA
    Brain 130:630-53. 2007
    ..association fibre bundles with DSI that match the observations in the isotope material: emanating from the parietal lobe, the superior longitudinal fasciculus subcomponents I, II and III; from the occipital-parietal region, the ..
  16. ncbi Response of neurons in the lateral intraparietal area during a combined visual discrimination reaction time task
    Jamie D Roitman
    Program in Neurobiology and Behavior, Department of Physiology and Biophysics, and Regional Primate Research Center, University of Washington, Seattle, Washington 98195 7290, USA
    J Neurosci 22:9475-89. 2002
    ..A threshold level of LIP activity appears to mark the completion of the decision process and to govern the tradeoff between accuracy and speed of perception...
  17. ncbi Neural basis of a perceptual decision in the parietal cortex (area LIP) of the rhesus monkey
    M N Shadlen
    Howard Hughes Medical Institute, Department of Physiology and Biophysics, and Regional Primate Research Center, University of Washington, Seattle, Washington 98195 7290, USA
    J Neurophysiol 86:1916-36. 2001
    ..The time course of the neural response suggests that LIP accumulates sensory signals relevant to the selection of a target for an eye movement...
  18. pmc A parcellation scheme for human left lateral parietal cortex
    Steven M Nelson
    Department of Neurology, Washington University, St Louis, MO 63110, USA
    Neuron 67:156-70. 2010
    The parietal lobe has long been viewed as a collection of architectonic and functional subdivisions...
  19. ncbi Distributed and overlapping cerebral representations of number, size, and luminance during comparative judgments
    Philippe Pinel
    INSERM Unit 562, Service Hospitalier Frederic Joliot, CEA DRM DSV, 4 Place du General Leclerc, 91401 Orsay Cedex, France
    Neuron 41:983-93. 2004
    ....
  20. ncbi That's my hand! Activity in premotor cortex reflects feeling of ownership of a limb
    H Henrik Ehrsson
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, 12 Queen Square, London WC1N 3BG, UK
    Science 305:875-7. 2004
    ..The neural activity in the premotor cortex reflected the feeling of ownership of the hand. This suggests that multisensory integration in the premotor cortex provides a mechanism for bodily self-attribution...
  21. ncbi Tuning curves for approximate numerosity in the human intraparietal sulcus
    Manuela Piazza
    Unité INSERM 562 Cognitive Neuroimaging, CEA DSV, 91401 Orsay Cedex, France
    Neuron 44:547-55. 2004
    ..Anatomically, the intraparietal site coding for number in humans is compatible with that observed in macaque monkeys. Our results therefore suggest an evolutionary basis for human elementary arithmetic...
  22. pmc The functional organization of the intraparietal sulcus in humans and monkeys
    Christian Grefkes
    Institute of Medicine, Research Center Julich, Germany
    J Anat 207:3-17. 2005
    ....
  23. ncbi Intentional maps in posterior parietal cortex
    Richard A Andersen
    Division of Biology, California Institute of Technology, Mail code 216 76, Pasadena 91125, USA
    Annu Rev Neurosci 25:189-220. 2002
    ..Attention and learning effects are also evident in the PPC. However, these effects may be general to cortex and operate in the PPC in the context of sensory-motor transformations...
  24. ncbi Intention, action planning, and decision making in parietal-frontal circuits
    Richard A Andersen
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Neuron 63:568-83. 2009
    ....
  25. ncbi Functional magnetic resonance imaging reveals the neural substrates of arm transport and grip formation in reach-to-grasp actions in humans
    Cristiana Cavina-Pratesi
    Department of Psychology, Durham University, Durham DH13LE, United Kingdom
    J Neurosci 30:10306-23. 2010
    ....
  26. pmc Probabilistic maps, morphometry, and variability of cytoarchitectonic areas in the human superior parietal cortex
    Filip Scheperjans
    Institute of Medicine, Research Center Julich, D 52425 Julich, Germany
    Cereb Cortex 18:2141-57. 2008
    ..Integrated into functional imaging experiments, they can improve structure-function investigations of the human SPC...
  27. ncbi Sources of mathematical thinking: behavioral and brain-imaging evidence
    S Dehaene
    Unité INSERM 334, Service Hospitalier Frederic Joliot, CEA DSV, 91401 Orsay Cedex, France
    Science 284:970-4. 1999
    ..Mathematical intuition may emerge from the interplay of these brain systems...
  28. ncbi The human inferior parietal lobule in stereotaxic space
    Svenja Caspers
    Research Centre Julich, Institute of Neurosciences and Biophysics Medicine, 52425 Julich, Germany
    Brain Struct Funct 212:481-95. 2008
    ..The cytoarchitectonic probabilistic maps of the seven IPL areas provide a robust anatomical reference and open new perspectives for further structure-function investigations of the human IPL...
  29. pmc A selective working memory impairment after transcranial direct current stimulation to the right parietal lobe
    Marian E Berryhill
    Department of Psychology, Temple University, Philadelphia, PA, USA Center for Cognitive Neuroscience, University of Pennsylvania, Philadelphia, PA, USA
    Neurosci Lett 479:312-6. 2010
    ..We previously found that patients with parietal lobe damage exhibited a selective WM impairment on recognition but not recall tasks...
  30. pmc Space and the parietal cortex
    Masud Husain
    Institute of Cognitive Neuroscience, University College, London, 17 Queen Square, London WC1N 3AR, UK
    Trends Cogn Sci 11:30-6. 2007
    Current views of the parietal cortex have difficulty accommodating the human inferior parietal lobe (IPL) within a simple dorsal versus ventral stream dichotomy...
  31. pmc Diffusion-weighted imaging tractography-based parcellation of the human parietal cortex and comparison with human and macaque resting-state functional connectivity
    Rogier B Mars
    Department of Experimental Psychology and Veterinary Services and Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, Oxford OX1 2JD, United Kingdom
    J Neurosci 31:4087-100. 2011
    ..In contrast, the human parietal cortex differs in the strength of its interactions between the central inferior parietal lobule region and the anterior prefrontal cortex...
  32. ncbi Experiencing oneself vs another person as being the cause of an action: the neural correlates of the experience of agency
    C Farrer
    Institut des Sciences Cognitives, 67 Boulevard Pinel, 69675 Bron Cedex, France
    Neuroimage 15:596-603. 2002
    ..The inferior parietal cortex, in contrast, represents movements in an allocentric coding system that can be applied to the actions of others as well as the self...
  33. ncbi A magnitude code common to numerosities and number symbols in human intraparietal cortex
    Manuela Piazza
    Institut National de la Sante et de la Recherche Medicale INSERM, Cognitive Neuroimaging Unit, Service Hospitalier Frederic Joliot, F 91401 Orsay, France
    Neuron 53:293-305. 2007
    ..They support the idea that symbols acquire meaning by linking neural populations coding symbol shapes to those holding nonsymbolic representations of quantities...
  34. ncbi Cortical mechanisms of human imitation
    M Iacoboni
    Brain Mapping Center, Neuropsychiatric Institute, Department of Psychiatry, UCLA School of Medicine, Los Angeles, CA 90095 7085, USA
    Science 286:2526-8. 1999
    ..Two areas with these properties were found in the left inferior frontal cortex (opercular region) and the rostral-most region of the right superior parietal lobule...
  35. ncbi Corticocortical connections of visual, sensorimotor, and multimodal processing areas in the parietal lobe of the macaque monkey
    J W Lewis
    California Institute of Technology, Pasadena, California 16825, USA
    J Comp Neurol 428:112-37. 2000
    ..They also support and extend previous evidence for multiple distributed networks that are implicated in multimodal integration, especially with regard to area VIP...
  36. ncbi Neural activity in macaque parietal cortex reflects temporal integration of visual motion signals during perceptual decision making
    Alexander C Huk
    Center for Perceptual Systems, Department of Psychology, University of Texas, Austin, Texas 78712, USA
    J Neurosci 25:10420-36. 2005
    ..Temporal integration may be a fundamental computation underlying higher cognitive functions that are dissociated from immediate sensory inputs or motor outputs...
  37. pmc The parietal cortex and episodic memory: an attentional account
    Roberto Cabeza
    Center for Cognitive Neuroscience, Duke University, B203 LSRC Building, Durham, North Carolina 27708, USA
    Nat Rev Neurosci 9:613-25. 2008
    ....
  38. ncbi Multisensory mechanisms in temporo-parietal cortex support self-location and first-person perspective
    Silvio Ionta
    Laboratory of Cognitive Neuroscience, Ecole Polytechnique Federale de Lausanne, Lausanne, 1015, Switzerland
    Neuron 70:363-74. 2011
    ....
  39. pmc Posterior parietal cortex and episodic retrieval: convergent and divergent effects of attention and memory
    J Benjamin Hutchinson
    Department of Psychology, Stanford University, Stanford, California 94305 2130, USA
    Learn Mem 16:343-56. 2009
    ....
  40. ncbi Neuronal synchronization along the dorsal visual pathway reflects the focus of spatial attention
    Markus Siegel
    Department of Neurophysiology and Pathophysiology, Center of Experimental Medicine, University Medical Center Hamburg Eppendorf, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
    Neuron 60:709-19. 2008
    ....
  41. pmc Episodic memory retrieval, parietal cortex, and the default mode network: functional and topographic analyses
    Carlo Sestieri
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 31:4407-20. 2011
    ..This latter finding demonstrates functional heterogeneity rather than homogeneity within the DMN during episodic memory retrieval...
  42. ncbi Regionally localized thinning of the cerebral cortex in schizophrenia
    Gina R Kuperberg
    Department of Psychiatry, Massachusetts General Hospital and Athinoula A Martinos Center for Biomedical Imaging, Charlestown, 02129, USA
    Arch Gen Psychiatry 60:878-88. 2003
    ....
  43. pmc Evidence for a distributed hierarchy of action representation in the brain
    Scott T Grafton
    Department of Psychology, Room 3837, Building 251, University of California, Santa Barbara, CA 93106, United States
    Hum Mov Sci 26:590-616. 2007
    ....
  44. pmc fMRI adaptation reveals mirror neurons in human inferior parietal cortex
    Trevor T J Chong
    St Vincent s Hospital Melbourne, Fitzroy, Victoria 3065, Australia
    Curr Biol 18:1576-80. 2008
    ..Here, we used fMRI adaptation to show that the right inferior parietal lobe (IPL) responds independently to specific actions regardless of whether they are observed or executed...
  45. ncbi Voluntary orienting is dissociated from target detection in human posterior parietal cortex
    M Corbetta
    Department of Neurology and Neurological Surgery, Washington University School of Medicine, 4525 Scott Avenue, St Louis, Missouri 63110, USA
    Nat Neurosci 3:292-7. 2000
    ....
  46. ncbi The functional role of the parieto-frontal mirror circuit: interpretations and misinterpretations
    Giacomo Rizzolatti
    University of Parma, Department of Neuroscience, and the Italian Institute of Technology, Via Volturno 39, I 43100 Parma, Italy
    Nat Rev Neurosci 11:264-74. 2010
    ....
  47. pmc Default network activity, coupled with the frontoparietal control network, supports goal-directed cognition
    R Nathan Spreng
    Department of Psychology, Harvard University, Cambridge MA 02138, USA
    Neuroimage 53:303-17. 2010
    ....
  48. ncbi Modulation of parietal activation by semantic distance in a number comparison task
    P Pinel
    , , Orsay Cedex, 91401, France
    Neuroimage 14:1013-26. 2001
    ..Our results support the assumption of a central semantic representation of numerical quantity that relies on a common parietal network shared among notations...
  49. ncbi The Parieto-Frontal Integration Theory (P-FIT) of intelligence: converging neuroimaging evidence
    Rex E Jung
    Departments of Neurology and Psychology, University of New Mexico, Albuquerque, NM 87106, USA
    Behav Brain Sci 30:135-54; discussion 154-87. 2007
    ..Moreover, the model provides a framework for testing new hypotheses in future experimental designs...
  50. pmc Free choice activates a decision circuit between frontal and parietal cortex
    Bijan Pesaran
    Center for Neural Science, New York University, New York, New York 10003, USA
    Nature 453:406-9. 2008
    ..Cells participating in this decision circuit may influence movement choices by providing a common bias to the selection of movement goals...
  51. ncbi Direct evidence for a parietal-frontal pathway subserving spatial awareness in humans
    Michel Thiebaut de Schotten
    INSERM Unit 610, Assistance Publique Hopitaux de Paris, Hopital de la Salpetriere, 75013 Paris, France
    Science 309:2226-8. 2005
    ..These findings suggest that parietal-frontal communication is necessary for the symmetrical processing of the visual scene...
  52. ncbi Direct visuomotor transformations for reaching
    Christopher A Buneo
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Nature 416:632-6. 2002
    ..Data obtained in the adjacent parietal reach region (PRR) indicate that this transformation may be achieved by vectorially subtracting hand location from target location, with both locations represented in eye-centred coordinates...
  53. ncbi Neural mechanisms of visual attention: how top-down feedback highlights relevant locations
    Yuri B Saalmann
    Department of Optometry and Vision Sciences, University of Melbourne, Parkville 3010, Australia
    Science 316:1612-5. 2007
    ..Parietal neurons may thus selectively increase activity in earlier sensory areas to enable focused spatial attention...
  54. ncbi Parietal cortex and attention
    Marlene Behrmann
    Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213 3890, USA
    Curr Opin Neurobiol 14:212-7. 2004
    The parietal lobe forms about 20% of the human cerebral cortex and is divided into two major regions, the somatosensory cortex and the posterior parietal cortex...
  55. ncbi Human parietal cortex in action
    Jody C Culham
    Department of Psychology, Social Science Centre, University of Western Ontario, London, Ontario, Canada, N6A 5C2
    Curr Opin Neurobiol 16:205-12. 2006
    ..We review the known subregions of the human posterior parietal cortex and the principles behind their organization...
  56. ncbi From thought to action: the parietal cortex as a bridge between perception, action, and cognition
    Jacqueline Gottlieb
    Center for Neurobiology and Behavior and Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Neuron 53:9-16. 2007
    The lateral intraparietal area (LIP) is a subdivision of the inferior parietal lobe that has been implicated in the guidance of spatial attention...
  57. pmc Dissociable connectivity within human angular gyrus and intraparietal sulcus: evidence from functional and structural connectivity
    Lucina Q Uddin
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94304, USA
    Cereb Cortex 20:2636-46. 2010
    ....
  58. ncbi Probabilistic fibre tract analysis of cytoarchitectonically defined human inferior parietal lobule areas reveals similarities to macaques
    Svenja Caspers
    Institute of Neuroscience and Medicine INM 2, INM 4, Research Centre Julich, 52425 Julich, Germany
    Neuroimage 58:362-80. 2011
    ....
  59. pmc Distinct representations of a perceptual decision and the associated oculomotor plan in the monkey lateral intraparietal area
    Sharath Bennur
    Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6074, USA
    J Neurosci 31:913-21. 2011
    ..The results suggest that perceptual decision-making and action selection are different brain processes that only appear to be inseparable under particular behavioral contexts...
  60. ncbi A representation of the hazard rate of elapsed time in macaque area LIP
    Peter Janssen
    Howard Hughes Medical Institute, National Primate Research Center and Department of Physiology and Biophysics, University of Washington, Box 357290, Seattle, Washington 98195, USA
    Nat Neurosci 8:234-41. 2005
    ..The results indicate that the parietal cortex contains circuitry for representing the time structure of environmental cues over a range of seconds...
  61. ncbi Numerical representation in the parietal lobes: abstract or not abstract?
    Roi Cohen Kadosh
    Institute of Cognitive Neuroscience and Department of Psychology, University College London, London, United Kingdom
    Behav Brain Sci 32:313-28; discussion 328-73. 2009
    ..We argue that numerical representation is primarily non-abstract and is supported by different neuronal populations residing in the parietal cortex...
  62. ncbi Connection patterns distinguish 3 regions of human parietal cortex
    M F S Rushworth
    Department of Experimental Psychology, University of Oxford, and Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, John Radcliffe Hospital, Oxford OX1 3UD, UK
    Cereb Cortex 16:1418-30. 2006
    ..Human parietal areas have anatomical connections resembling those of functionally related macaque parietal areas...
  63. ncbi Cortical connections of the inferior parietal cortical convexity of the macaque monkey
    Stefano Rozzi
    Dipartimento di Neuroscienze, Sezione di Fisiologia, Universita di Parma, I 43100 Parma, Italy
    Cereb Cortex 16:1389-417. 2006
    ....
  64. ncbi FMRI evidence for a 'parietal reach region' in the human brain
    Jason D Connolly
    CIHR Group on Action and Perception, Department of Psychology, University of Western Ontario, London, Ontario, N6A 5C2, Canada
    Exp Brain Res 153:140-5. 2003
    ..We therefore conclude that activation in this region is related to specific motor intent; i.e. it encodes information related to the subject's intention to make a specific movement to a particular spatial location...
  65. ncbi Observer-independent cytoarchitectonic mapping of the human superior parietal cortex
    Filip Scheperjans
    Institute of Medicine, Research Center Jülich and Brain Imaging Center West, D 52425 Julich, Germany
    Cereb Cortex 18:846-67. 2008
    ..These areas are possible structural correlates of functional segregations within the SPC...
  66. pmc Topographic maps in human frontal and parietal cortex
    Michael A Silver
    School of Optometry, Helen Wills Neuroscience Institute, and Henry H Wheeler, Jr Brain Imaging Center, University of California, Berkeley, Berkeley, CA 94720, USA
    Trends Cogn Sci 13:488-95. 2009
    ..The study of higher-order topographic cortex promises to yield unprecedented insights into the neural mechanisms of cognitive processes and, in conjunction with parallel studies in non-human primates, into the evolution of cognition...
  67. pmc Feature binding, attention and object perception
    A Treisman
    Department of Psychology, Princeton University, NJ 08544 1010, USA
    Philos Trans R Soc Lond B Biol Sci 353:1295-306. 1998
    ..However, indirect measures of priming and interference suggest that more information may be implicitly available than we can consciously access...
  68. ncbi Wide-field retinotopy defines human cortical visual area v6
    Sabrina Pitzalis
    Neuroimaging Laboratory, Santa Lucia Foundation, Istituto di Ricovero e Cura a Carattere Scientifico, 00179 Rome, Italy
    J Neurosci 26:7962-73. 2006
    ....
  69. ncbi Functional heterogeneity of macaque lateral intraparietal neurons
    Elsie Premereur
    Laboratorium voor Neuro en Psychofysiologie, Katholieke Universiteit Leuven, 3000 Leuven, Belgium
    J Neurosci 31:12307-17. 2011
    ..Our results suggest that between-study differences in neuronal selection may have contributed significantly to the findings of different research groups with respect to the functional role of area LIP...
  70. ncbi Two different streams form the dorsal visual system: anatomy and functions
    Giacomo Rizzolatti
    Dipartimento di Neuroscienze, Universita di Parma, Via Volturno, 43100 Parma, Italy
    Exp Brain Res 153:146-57. 2003
    ..It, however, also plays a crucial role in space perception and action understanding. The putative mechanisms linking action and perception in the v-d stream is discussed...
  71. pmc Hyperexcitability of parietal-motor functional connections in the intact left-hemisphere of patients with neglect
    Giacomo Koch
    Laboratorio di Neurologia Clinica e Comportamentale, Fondazione Santa Lucia IRCCS, Rome, Italy
    Brain 131:3147-55. 2008
    ..Our results provide 'direct' evidence for pathological over-excitability of the LH in the neglect syndrome, as quantified by left PPC influences on left M1, with implications for possible treatment...
  72. ncbi Neuroimaging of cognitive functions in human parietal cortex
    J C Culham
    Department of Psychology, University of Western Ontario, London, Ontario N6A 5C2, Canada
    Curr Opin Neurobiol 11:157-63. 2001
    ..However, parietal activation generalizes across a wide variety of cognitive tasks and the extension of human brain mapping into higher-order "association cortex" may prove to be a challenge...
  73. ncbi The neural bases of complex tool use in humans
    Scott H Johnson-Frey
    Center for Cognitive Neuroscience, Dartmouth College, 6162 Moore Hall, Hanover, NH 03755 3569, USA
    Trends Cogn Sci 8:71-8. 2004
    ..Together, these findings indicate that behaviors associated with complex tool use arise from functionally specialized networks involving temporal, parietal and frontal areas within the left cerebral hemisphere...
  74. ncbi Attentional load and sensory competition in human vision: modulation of fMRI responses by load at fixation during task-irrelevant stimulation in the peripheral visual field
    Sophie Schwartz
    Laboratory for Neurology and Imaging of Cognition, Department of Neurosciences, University of Geneva, Switzerland
    Cereb Cortex 15:770-86. 2005
    ..These distinct mechanisms in selective visual processing may be integrated within posterior parietal areas, rather than earlier occipital cortex...
  75. ncbi Diffusion-weighted imaging tractography-based parcellation of the human lateral premotor cortex identifies dorsal and ventral subregions with anatomical and functional specializations
    Valentina Tomassini
    Centre for Functional MRI of the Brain, University of Oxford, Oxford OX3 9DU, United Kingdom
    J Neurosci 27:10259-69. 2007
    ....
  76. ncbi Neural correlates of decision variables in parietal cortex
    M L Platt
    Center for Neural Science, New York University, New York 10003, USA
    Nature 400:233-8. 1999
    ..Our data indicate that a decision-theoretic model may provide a powerful new framework for studying the neural processes that intervene between sensation and action...
  77. ncbi The counting Stroop: an interference task specialized for functional neuroimaging--validation study with functional MRI
    G Bush
    Department of Radiology, Massachusetts General Hospital, Boston, USA
    Hum Brain Mapp 6:270-82. 1998
    ..These findings have ramifications for attentional, cognitive interference, learning, and motor control mechanism theories...
  78. ncbi Visual topography of human intraparietal sulcus
    Jascha D Swisher
    Perceptual Neuroimaging Laboratory, Program in Neuroscience and Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
    J Neurosci 27:5326-37. 2007
    ..These visual maps may provide a practical framework in which to characterize the functional organization of human IPS...
  79. pmc Distinct encoding of spatial and nonspatial visual information in parietal cortex
    David J Freedman
    Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neurosci 29:5671-80. 2009
    ....
  80. pmc Dorsal premotor neurons encode the relative position of the hand, eye, and goal during reach planning
    Bijan Pesaran
    Division of Biology, California Institute of Technology, Pasadena, California 91125, USA
    Neuron 51:125-34. 2006
    ..Such a relative position code may play an important role in coordinating hand and eye movements by computing their relative position...
  81. ncbi Experience-dependent representation of visual categories in parietal cortex
    David J Freedman
    Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, Massachusetts 02115, USA
    Nature 443:85-8. 2006
    ..This indicates that LIP might be an important nexus for the transformation of visual direction selectivity to more abstract representations that encode the behavioural relevance, or meaning, of stimuli...
  82. ncbi Probabilistic reasoning by neurons
    Tianming Yang
    Howard Hughes Medical Institute, Department of Physiology and Biophysics, National Primate Research Center, University of Washington, Box 357290, Seattle, Washington 98195 7290, USA
    Nature 447:1075-80. 2007
    ..Monkeys learned to combine probabilistic information from the shape combinations. Moreover, neurons in the parietal cortex reveal the addition and subtraction of probabilistic quantities that underlie decision-making on this task...
  83. ncbi Schizophrenia and the inferior parietal lobule
    E Fuller Torrey
    Laboratory Research, The Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, MD 20815, USA
    Schizophr Res 97:215-25. 2007
    ..Studies of the neuroanatomical localization of schizophrenia have not given sufficient attention to the inferior parietal lobule (IPL)...
  84. ncbi White matter (dis)connections and gray matter (dys)functions in visual neglect: gaining insights into the brain networks of spatial awareness
    Fabrizio Doricchi
    Dipartimento di Psicologia 39, Universita degli Studi di Roma La Sapienza, Rome, Italy
    Cortex 44:983-95. 2008
    Seminal case reports collected during the middle part of the XX century, designated the parietal lobe as the principal area of damage in patients suffering from contralesional spatial neglect (Brain WC...
  85. ncbi Control of attention shifts between vision and audition in human cortex
    Sarah Shomstein
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA
    J Neurosci 24:10702-6. 2004
    ..These findings reveal that the attentional control functions of posterior parietal and superior prefrontal cortices are not limited to the visual domain but also include the control of crossmodal shifts of attention...
  86. ncbi A review of the evidence for a disengage deficit following parietal lobe damage
    B J Losier
    Department of Psychology, Cape Breton Regional Hospital, Sydney, B1P 1P3, Nova Scotia, Canada
    Neurosci Biobehav Rev 25:1-13. 2001
    ..Similar, but usually smaller, effects were observed in patients with homologous left-hemisphere damage. The implications of these results for current models of the role of the parietal lobes in attentional orienting are discussed...
  87. ncbi Parietal cortex mediates voluntary control of spatial and nonspatial auditory attention
    Sarah Shomstein
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA
    J Neurosci 26:435-9. 2006
    ....
  88. ncbi Interactions between number and space in parietal cortex
    Edward M Hubbard
    INSERM Unit 562 Cognitive Neuroimaging, Service Hospitalier Frederic Joliot, 4 Place du General Leclerc, F94101 Orsay, France
    Nat Rev Neurosci 6:435-48. 2005
    ....
  89. ncbi Topographical layout of hand, eye, calculation, and language-related areas in the human parietal lobe
    Olivier Simon
    Unité INSERM 334, IFR 49, Service Hospitalier Frederic Joliot, CEA DSV, Orsay, France
    Neuron 33:475-87. 2002
    ..These results suggest human homologs of the monkey areas AIP, MIP, V6A, and LIP and imply a large cortical expansion of the inferior parietal lobule correlated with the development of human language and calculation abilities...
  90. pmc Memory retrieval and the parietal cortex: a review of evidence from a dual-process perspective
    Kaia L Vilberg
    Center for the Neurobiology of Learning and Memory, University of California Irvine, Irvine, CA 92697 3800, USA
    Neuropsychologia 46:1787-99. 2008
    ..D. (2000). The episodic buffer: A new component of working memory? Trends in Cognitive Sciences, 4, 417-423]...
  91. ncbi Anatomical and functional connectivity of cytoarchitectonic areas within the human parietal operculum
    Simon B Eickhoff
    Department of Psychiatry and Psychotherapy, Rheinisch Westfälische Technische Hochschule Aachen University, D 52074 Aachen, Germany
    J Neurosci 30:6409-21. 2010
    ..Differences between anatomical and functional connectivity as well as between species, however, highlight the need for an integrative view on connectivity, including comparison and cross-validation of results from different approaches...
  92. ncbi Cortical control of visually guided reaching: evidence from patients with optic ataxia
    Hans Otto Karnath
    Section Neuropsychology, Department of Cognitive Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Tubingen, Germany
    Cereb Cortex 15:1561-9. 2005
    ..These lateral and medial structures seem to be integral to the fast control of visually guided reaching in humans...
  93. ncbi Social brain dysfunctions in schizophrenia: a review of neuroimaging studies
    Eric Brunet-Gouet
    Service de Psychiatrie Adulte, Inserm ERI 0015, Hopital de Versailles, 177 route de Versailles, 78150 Le Chesnay, France
    Psychiatry Res 148:75-92. 2006
    ..hemodynamic response in the medial prefrontal cortex, the prefrontal cortex, the amygdala, the inferior parietal lobe, i.e., a set of regions known to be critically involved in social cognition...
  94. ncbi Integrated model of visual processing
    J Bullier
    Centre de Recherche Cerveau et Cognition CNRS UPS, Universite Paul Sabatier, 133 route de Narbonne, 31062, Cedex 4, Toulouse, France
    Brain Res Brain Res Rev 36:96-107. 2001
    ....
  95. ncbi Is the mirror neuron system involved in imitation? A short review and meta-analysis
    Pascal Molenberghs
    The University of Queensland, Queensland Brain Institute and School of Psychology, St Lucia, Australia
    Neurosci Biobehav Rev 33:975-80. 2009
    ..Our results suggest that parietal and frontal regions which extend beyond the classical mirror neuron network are crucial for imitation...
  96. ncbi Perceptual systems controlling speech production
    Novraj S Dhanjal
    Division of Neuroscience and Mental Health and Medical Research Council Clinical Sciences Centre, Imperial College London, London W12 0NN, United Kingdom
    J Neurosci 28:9969-75. 2008
    ..These findings have novel implications for the acquisition and maintenance of fluent speech...
  97. pmc Some surprising findings on the involvement of the parietal lobe in human memory
    Ingrid R Olson
    Department of Psychology, Temple University, Philadelphia, PA 19122, USA
    Neurobiol Learn Mem 91:155-65. 2009
    The posterior parietal lobe is known to play some role in a far-flung list of mental processes: linking vision to action (saccadic eye movements, reaching, grasping), attending to visual space, numerical calculation, and mental rotation...
  98. ncbi Watching social interactions produces dorsomedial prefrontal and medial parietal BOLD fMRI signal increases compared to a resting baseline
    Marco Iacoboni
    UCLA Brain Mapping Center, University of California, Los Angeles, CA 90095, USA
    Neuroimage 21:1167-73. 2004
    ....
  99. ncbi The priming method: imaging unconscious repetition priming reveals an abstract representation of number in the parietal lobes
    L Naccache
    Unité INSERM 334, Service Hospitalier Frederic Joliot, CEA DRM DSV, 4 Place du General Leclerc, F 91401 Orsay Cedex, France
    Cereb Cortex 11:966-74. 2001
    ....
  100. ncbi Neural correlates of perceptual rivalry in the human brain
    E D Lumer
    Wellcome Department of Cognitive Neurology, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK
    Science 280:1930-4. 1998
    ..These results suggest that frontoparietal areas play a central role in conscious perception, biasing the content of visual awareness toward abstract internal representations of visual scenes, rather than simply toward space...
  101. ncbi Cerebral correlates of alerting, orienting and reorienting of visuospatial attention: an event-related fMRI study
    Christiane M Thiel
    Institute of Medicine, Research Centre Julich, 52425, Julich, Germany
    Neuroimage 21:318-28. 2004
    ..Alerting effects were seen in extrastriate regions which suggest that increased phasic alertness results in a top-down modulation of neural activity in visual processing areas...

Research Grants63

  1. NEURAL MECHANISMS OF CUTANEOUS SPATIAL INTEGRATION
    Esther P Gardner; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): This project analyzes the role of somatosensory neurons in the parietal lobe during performance of skilled manual tasks...
  2. Development of a Microfluidic Thermal Regulator for Studies of Cortical Function
    LEAH ANN KRUBITZER; Fiscal Year: 2013
    ..g., hippocampus), working memory (e.g., prefrontal cortex), and attention (e.g., parietal lobe)...
  3. A Unified Neuroanatomical Model of Speech Production and Perception: Implications
    Christopher Rorden; Fiscal Year: 2013
    ..been controversial, recent studies suggest that damage to Broca's area and the left posterior inferior parietal lobe cause AOS and conduction aphasia, respectively...
  4. Mechanisms of Mathematics Deficits in Fetal Alcohol Spectrum Disorders
    NICOLE ASHLEY CROCKER; Fiscal Year: 2012
    ..in areas known to be associated with mathematics ability and numerical processing, particularly the parietal lobe. The overarching goal of the current study is to characterize mathematics deficits in children with FASD by ..
  5. Spatial and Temporal Visual Attention in Infants with Fragile X Syndrome
    Faraz Farzin; Fiscal Year: 2010
    ..and has been characterized by specific deficits in visual processing abilities associated with the parietal lobe of the brain...
  6. An ERP Study of Infant Numerosity in Fetal Alcohol Syndrome
    Sandra W Jacobson; Fiscal Year: 2012
    ..the ability to mentally represent and manipulate number, which has been linked to alcohol-related deficits in parietal lobe function in neuroimaging studies...
  7. Cortical organization of object knowledge before and after brain surgery
    BRADFORD ZACK MAHON; Fiscal Year: 2013
    ..Those cognitive abilities can be compromised after neurosurgery for removal of temporal or parietal lobe brain tumors...
  8. Visual-Motor Integration
    Jerome Sanes; Fiscal Year: 2009
    ..brain representations become created and modified, especially regarding whether motor plans are formed in the parietal lobe and then relayed to frontal cortex or alternatively that the parietal lobe relays fundamental information to ..
  9. REORGANIZATION OF MOTOR CORTEX FOLLOWING BRAIN INJURY
    Randolph J Nudo; Fiscal Year: 2013
    ..pathways between the ventral premotor cortex in the frontal lobe and somatosensory cortex in the parietal lobe that occurs spontaneously after cortical infarct...
  10. An fMRI study of the effect of working memory training on ADHD brain dysfunction
    Michael C Stevens; Fiscal Year: 2010
    ..in non-ADHD enhances normal working memory ability by altering brain activity in prefrontal cortex and the parietal lobe. However, no study has characterized brain activity changes following working memory training in ADHD to ..
  11. Behavioral and Neurologic Factors in Speech Learning
    PATRICK C WONG; Fiscal Year: 2012
    ..which is indicated by increased brain responses in auditory association cortex and the recruitment of the parietal lobe;2) poor word learning resulting from a lack of phonetic representation and can be remediated by first training ..
  12. HEPATIC ENCEPHALOPATHY--NEUROPSYCHOLOGY & NEUROCHEMISTRY
    Michael Thomas; Fiscal Year: 2001
    ..absolute cerebral metabolite levels of myo-inositol, choline, and glutamine/glutamate in the frontal lobe, parietal lobe and basal ganglia of a matched group of SHE patients and healthy controls...
  13. The Neurophysiology of visual memory
    MICHAEL ELLIS GOLDBERG; Fiscal Year: 2010
    ..We have discovered that neurons in the lateral intraparietal area, a region in the parietal lobe, maintain a memory of objects in the environment across several trials...
  14. PSYCHOLOGICAL AND NEURAL BASES OF SPATIAL COGNITION
    Marlene Behrmann; Fiscal Year: 1999
    ..general acceptance in the animal and human literature that spatial information is neurally instantiated in the parietal lobe, there is little agreement on the frame of reference within which spatial representations are defined...
  15. Cognition and Action
    Jerome Sanes; Fiscal Year: 2004
    This project focuses upon patterns of human brain activation in the frontal and parietal lobe related to continuous movement tracking and motor learning...
  16. Cognitive and Spatial Systems in Action
    Laurel Buxbaum; Fiscal Year: 2006
    ..anatomically and functionally distinct components: the action representation system, mediated by the inferior parietal lobe, and the action execution system, mediated by dorsal stream structures in fronto-parietal cortex...
  17. The nature of parietal involvement in visual short-term memory
    Marian Berryhill; Fiscal Year: 2009
    ..b>Parietal lobe strokes are relatively common and the behavioral consequences on vision and action are devastating...
  18. Neural Patterns of Visual Learning in Schizophrenia
    Nicola Cascella; Fiscal Year: 2006
    ..DS volunteers will exhibit a significantly reduced BOLD response in the inferior parietal lobe before and after training...
  19. A gene expression study of regional vulnerability in Alzheimer's disease
    Jeremy Miller; Fiscal Year: 2009
    ..cells, followed later by degeneration of the structurally similar CAS pyramidal neurons, posterior, superior parietal lobe, and eventually by degeneration of most of the cerebral cortices, sparing cerebellum and primary sensory ..
  20. Fetal Alcohol Syndrome: Neuropsychological Assessment of Children
    SARAH MATTSON; Fiscal Year: 2007
    ..shifting" of visual attention. These areas have been linked to the parietal lobe, an area of the brain affected by prenatal alcohol exposure...
  21. PSYCHOPHYSICAL STRUCTURE OF HUMAN VISION
    Jeremy Wolfe; Fiscal Year: 2003
    ..internal structure represented? Further, we will study an important neuropsychological patient whose bilateral parietal lobe lesions appear to reduce his perceptual world to the current object of attention...
  22. Sensory Re-Weighting and Re-Alignment: Cerebellar and Parietal Contributions
    HANNAH BLOCK; Fiscal Year: 2009
    ..for these processes by studying individuals with focal brain damage, initially focusing on the cerebellum and parietal lobe. Finally, we will discuss how these processes might be manipulated to compensate for deficits in patient ..
  23. NEURAL MODELS OF HEMINEGLECT USING BASIS FUNCTIONS
    Alexandre Pouget; Fiscal Year: 2002
    ..this proposal is to develop a model of hemineglect - the neurological syndrome resulting from lesions in the parietal lobe - based on the response of single neurons in the parietal cortex...
  24. Discrimination of object orientation by visual cortex
    Julianne Rollenhagen; Fiscal Year: 2003
    ..The results of these studies will elucidate the manner in which object orientation is encode in the brain and provide insight into the nature of processes impaired following parietal lobe injury.
  25. Visual pattern memory: neural basis in humans
    James Muller; Fiscal Year: 2005
    ..task-relevant or otherwise), when presented during a working memory delay, alter working memory in the parietal lobe while leaving prefrontal working memory unchanged...
  26. BRAIN DAMAGE EFFECTS ON FEATURE TRACES IN MEMORY
    Lynn Robertson; Fiscal Year: 1999
    ..They are absent in groups of patients with left parietal lobe lesions...
  27. Neuropsychology of human spatial cognition
    Kevin Thomas; Fiscal Year: 2003
    ..group and 3 patient groups (unilateral right hippocampal lesions, unilateral left hippocampal lesions, and parietal lobe lesions) on tasks of spatial cognition...
  28. Neuroimaging and Functional Senscence in Aging
    Nikolaos Makris; Fiscal Year: 2002
    ..abstract_text> ..
  29. Parietal mechanisms of vision and attention
    Jacqueline Gottlieb; Fiscal Year: 2007
    ..In humans, unilateral damage to the parietal lobe can cause severe contralateral neglect - a syndrome characterized by failure to notice and orient toward ..
  30. Relational Memory and Aging: Role of Prefrontal Lobe
    Roberto Cabeza; Fiscal Year: 2009
    ..Taken together, the results of these studies will clarify the neural correlates of age-related deficits in RM and will have important implications for the promotion of health. ..
  31. NEURAL EFFECTS OF INTERFERENCE WITH WORKING MEMORY
    Clayton Curtis; Fiscal Year: 2002
    ..abstract_text> ..
  32. NEURAL MECHANISMS OF CUTANEOUS SPATIAL INTEGRATION
    ESTHER GARDNER; Fiscal Year: 2008
    This project analyzes the role of somatosensory neurons in the parietal lobe during performance of skilled manual tasks...
  33. Multimodal maps of human imitative behavior
    Marco Iacoboni; Fiscal Year: 2004
    ....
  34. NEUROINFORMATICS AND EYE-HAND COORDINATION
    ESTHER GARDNER; Fiscal Year: 2005
    ....
  35. FUNCTIONAL MRI OF HUMAN BRAIN LANGUAGE SYSTEMS
    Jeffrey R Binder; Fiscal Year: 2010
    ..abstract_text> ..
  36. Prenatal Virally Induced Brain Disorder in Mouse
    SEYYED FATEMI; Fiscal Year: 2009
    ..In addition, it is expected that the results will provide clues that will lead to fundamental advances in our knowledge of the pathogenesis of schizophrenia and, therefore, of how it can be prevented and treated. ..
  37. SPATIAL INFLUENCES ON LANGUAGE FUNCTION
    H Coslett; Fiscal Year: 2002
    ..abstract_text> ..
  38. Varenicline and Smoking Cessation in Schizophrenia
    SEYYED HOSSEIN FATEMI; Fiscal Year: 2010
    ..Such outcomes will be significant, because they will offer a new treatment for smoking cessation in this vulnerable population. ..
  39. Cognitive neuroscience of temporal processing
    H Branch Coslett; Fiscal Year: 2010
    ..brain lesions involving the basal ganglia as well as specific cortical regions (lateral frontal lobe, inferior parietal lobe;temporal lobe)...
  40. Sensory-motor Integration in the Primate Cortex
    Michael Graziano; Fiscal Year: 2008
    ..The proposed research may also contribute to the development of limb prosthetics and artificial devices for object manipulation. ..
  41. BACK PROPAGATION TECHNIQUE-MODELING CORTICAL COMPUTATION
    David Zipser; Fiscal Year: 1993
    ..with three- dimensional representation, develop a primary visual cortex model using our previous observations on orientation and stereo, and build models of the sensory-motor integration processes thought to occur in the parietal lobe.
  42. Acoustic Interference on Attention in HIV Patients
    Dardo Tomasi; Fiscal Year: 2003
    ..More generally, this study will also improve the understanding of the neural effects of acoustic noise interference during fMRI studies in healthy populations. ..
  43. ANALYSIS OF STRUCTURE-FROM-MOTION IN VISUAL CORTEX
    RALPH SIEGEL; Fiscal Year: 2003
    ..These studies will be crucial in correctly choosing which parietal representations are best modified through therapy when there are spatial deficits in human subjects caused by parietal damage through stroke. ..
  44. Cognitive reserve and age-related brain changes
    Adam Brickman; Fiscal Year: 2005
    ..Results from the study will provide important insights into the normal aging process and will yield valuable information towards understanding the underpinnings of age-associated pathologies. ..
  45. NEUROPHYSIOLOGY OF POSTERIOR PARIETAL CORTEX
    Michael Steinmetz; Fiscal Year: 1993
    ..These data will be examined to determine if there exists an organized representation of extrapersonal space in the parietal lobe.
  46. Neural circuitry of the parietal lobe
    RALPH SIEGEL; Fiscal Year: 2006
    ..The proposal examines these two functions in inferior parietal lobe from a novel perspective- the neural circuit...
  47. Motor Imagery as a Measure of Pain Severity
    H Coslett; Fiscal Year: 2007
    ..Finally, as mental motor imagery tasks require minimal language capacity or abstract reasoning, we propose to investigate the use of these measures in subjects with cognitive impairment. ..
  48. The cognitive neuroscience of body knowledge
    H Coslett; Fiscal Year: 2007
    ..Understanding the cerebral basis of motor control and the body schema is likely to contribute substantially to the development of interventions that target these representations. [unreadable] [unreadable]..
  49. Capacity Limits in Multi-Tasking
    Rene Marois; Fiscal Year: 2008
    ..In addition, this project will investigate how response selection demands affect perception by determining whether our inability at doing more than one task at a time affects our visual cortex ability to "see". ..
  50. The influence semantics on syntactic analysis: fMRI study
    Sharlene Newman; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  51. BODY REPRESENTATIONS--NEUROPSYCHOLOGY AND ANATOMIC BASIS
    H Coslett; Fiscal Year: 2001
    ..The potential clinical significance of this work is also clear. If, as hypothesized, the body schema is crucial to action, interventions targeting this representations may have important therapeutic implications. ..
  52. Epigenesis of Cerebral Asymmetry in Twins
    Mark Eckert; Fiscal Year: 2004
    ....
  53. Functional Neuroimaging of Executive Processing
    Scott Huettel; Fiscal Year: 2002
    ..This research program will inform studies of executive processing, while providing proof-of-concept data for future applications for research support. ..
  54. FMRI CINGULATE DISSECTION IN CINGULOTOMY PATIENTS & ADHD
    ALLAN BUSH; Fiscal Year: 2002
    ....
  55. Brain activation in developmental communication disorder
    James Booth; Fiscal Year: 2004
    ..This project will provide tasks, an experimental approach, and a method for evaluating differences between groups with communication disorders that could potentially be used as a diagnostic and intervention tool. ..
  56. NEUROBEHAVIORAL FEATURES & MESIAL TEMPORAL LOBE EPILEPSY
    Bruce Hermann; Fiscal Year: 2005
    ..The findings will have potential implications for treatment as well as the understanding of the pathophysiology and natural history of TLE. ..
  57. Neuroanatomy and Cognition in Velocardiofacial Syndrome
    Wendy Kates; Fiscal Year: 2005
    ....
  58. Role of the Orbitofrontal Cortex in Regulating Emotion
    ARTHUR SHIMAMURA; Fiscal Year: 2005
    ..In particular, issues of inhibitory control, reward-feedback analysis, and decision making will be considered in light of issues related to drug abuse, such as compulsions, cue-induced cravings, risk taking behavior. ..
  59. Diffuse optical brain imaging for stroke rehabilitation
    Gary Strangman; Fiscal Year: 2007
    ..Importantly, use of the DOT technology in such a research program is expected to enable the investigation of tasks and populations that are otherwise beyond the reach of existing brain imaging technologies. [unreadable] [unreadable]..
  60. Neuroimaging of Executive Processing
    Scott Huettel; Fiscal Year: 2008
    ..g., frontal lobe damage, schizophrenia, Parkinson's disease). [unreadable] [unreadable]..
  61. Neural Compensation and Economic Decision Making in Aging
    Scott Huettel; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
  62. Understanding memory for pictures in Alzheimer's disease
    BRANDON ALLY; Fiscal Year: 2008
    ..Finally, Aim 3 will use grayscale versus color pictures and a level of processing manipulation to evaluate two hypotheses regarding how pictures might affect memory processes in AD. [unreadable] [unreadable] [unreadable]..
  63. TREATMENT OF SOCIAL PHOBIA--MEDIATORS AND MODERATORS
    Stefan Hofmann; Fiscal Year: 2002
    ..The main hypothesis is that perceived emotional control will mediate treatment outcome and generality of effectiveness independent of the specific treatment condition. ..