- Osteoarthritis development in novel experimental mouse models induced by knee joint instability
Department of Orthopaedic Surgery, University of Tokyo, Tokyo, Japan
Osteoarthritis Cartilage 13:632-41. 2005
..To apply approaches from mouse genomics, this study created experimental mouse OA models by producing instability in the knee joints...
- Grand challenge competition to predict in vivo knee loads
Benjamin J Fregly
Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, Florida, USA
J Orthop Res 30:503-13. 2012
- Loading of the knee joint during activities of daily living measured in vivo in five subjects
Julius Wolff Institute, Charite Universitatsmedizin Berlin, 13353 Berlin, Germany
J Biomech 43:2164-73. 2010
Detailed knowledge about loading of the knee joint is essential for preclinical testing of implants, validation of musculoskeletal models and biomechanical understanding of the knee joint...
- A human knee joint model considering fluid pressure and fiber orientation in cartilages and menisci
K B Gu
Department of Mechanical and Manufacturing Engineering, University of Calgary, 2500 University Drive, NW, Calgary, Alberta, Canada T2N 1N4
Med Eng Phys 33:497-503. 2011
..The present study indicates the necessity of implementing the fluid pressure and anisotropic fibril reinforcement in articular cartilage for a more accurate understanding of the mechanics of the knee...
- Responsiveness to change and reliability of measurement of radiographic joint space width in osteoarthritis of the knee: a systematic review
W M Reichmann
Department of Orthopedic Surgery, Brigham and Women s Hospital, Boston, MA, USA
Osteoarthritis Cartilage 19:550-6. 2011
..The goal of this systematic review was to report the responsiveness to change and reliability of conventional radiographic joint space width (JSW) measurement...
- Effect of superficial collagen patterns and fibrillation of femoral articular cartilage on knee joint mechanics-a 3D finite element analysis
M E Mononen
Department of Applied Physics, University of Eastern Finland, POB 1627, FI 70211 Kuopio, Finland
J Biomech 45:579-87. 2012
..of superficial collagen fibril patterns and collagen fibrillation of cartilage on stresses and strains within a knee joint. A 3D finite element model of a knee joint with cartilage and menisci was constructed based on magnetic ..
- Gait kinematics and passive knee joint range of motion in children with hypermobility syndrome
Francis A Fatoye
Department of Health Professions, Faculty of Health, Psychology and Social Care, Manchester Metropolitan University, Elizabeth Gaskell Campus, Hathersage Road, Manchester M13 0JA, UK
Gait Posture 33:447-51. 2011
..The extent of passive knee joint range of motion (ROM) has also not been well reported in children with HMS...
- The treatment of chondral and osteochondral defects of the knee with autologous matrix-induced chondrogenesis (AMIC): method description and recent developments
Jan Philipp Benthien
Department of Orthopaedic Surgery, University of Basel, Basel, Switzerland
Knee Surg Sports Traumatol Arthrosc 19:1316-9. 2011
..This technical note describes the method of autologous matrix-induced chondrogenesis (AMIC), a one-step procedure combining subchondral microfracture with the fixation of a collagen I/III membrane with fibrin glue or sutures...
- Functional mesenchymal stem cell niches in adult mouse knee joint synovium in vivo
Tobias B Kurth
University of Aberdeen, Aberdeen, UK
Arthritis Rheum 63:1289-300. 2011
..We previously reported that human synovium contains cells that, after culture expansion, display properties of mesenchymal stem cells (MSCs). The objective of this study was to identify MSCs in native synovium in vivo...
- Effect of a home program of hip abductor exercises on knee joint loading, strength, function, and pain in people with knee osteoarthritis: a clinical trial
Elizabeth A Sled
School of Rehabilitation Therapy, Queen s University, L D Acton Building, 31 George St, Kingston, Ontario, Canada K7L 3N6
Phys Ther 90:895-904. 2010
..Hip abductor muscle weakness may result in impaired frontal-plane pelvic control during gait, leading to greater medial compartment loading in people with knee osteoarthritis (OA)...
- Patient satisfaction after total knee arthroplasty: who is satisfied and who is not?
Robert B Bourne
University Hospital, London Health Sciences Centre, University of Western Ontario, 339 Windermere Road, London, ON N6A 5A5, Canada
Clin Orthop Relat Res 468:57-63. 2010
..7x greater risk), a low 1-year WOMAC (2.5x greater risk), preoperative pain at rest (2.4x greater risk) and a postoperative complication requiring hospital readmission (1.9x greater risk)...
- Do knee abnormalities visualised on MRI explain knee pain in knee osteoarthritis? A systematic review
Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
Ann Rheum Dis 70:60-7. 2011
- Neurovascular invasion at the osteochondral junction and in osteophytes in osteoarthritis
Academic Rheumatology, University of Nottingham, City Hospital, Hucknall Road, Nottingham, Notts NG5 1PB, UK
Ann Rheum Dis 66:1423-8. 2007
..Normal adult articular cartilage is thought to be avascular and aneural...
- Correlation between the knee adduction torque and medial contact force for a variety of gait patterns
Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, FL, USA
J Orthop Res 25:789-97. 2007
..These results support the hypothesis that the knee adduction torque is highly correlated with medial compartment contact force and medial to total force ratio during gait...
- Prevalence of knee symptoms and radiographic and symptomatic knee osteoarthritis in African Americans and Caucasians: the Johnston County Osteoarthritis Project
Joanne M Jordan
Thurston Arthritis Research Center and Department of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599 7280, USA
J Rheumatol 34:172-80. 2007
..To report contemporary estimates of the prevalence of knee-related osteoarthritis (OA) outcomes in African Americans and Caucasians aged > or = 45 years...
- The discordance between clinical and radiographic knee osteoarthritis: a systematic search and summary of the literature
Arthritis Research Campaign National Primary Care Centre, Keele University, Staffordshire, ST5 5BG, United Kingdom
BMC Musculoskelet Disord 9:116. 2008
- Knee joint kinematics in gait and other functional activities measured using flexible electrogoniometry: how much knee motion is sufficient for normal daily life?
P J Rowe
Department of Physiotherapy, Queen Margaret University College, EH6 8HF, Edinburgh, UK
Gait Posture 12:143-55. 2000
The knee joint kinematics of a group (n=20) of elderly normal subjects (mean age=67 years) were investigated using flexible electrogoniometry...
- The knee adduction moment during gait in subjects with knee osteoarthritis is more closely correlated with static alignment than radiographic disease severity, toe out angle and pain
D E Hurwitz
Department of Orthopedic Surgery, Rush Presbyterian St Luke s Medical Center, Rush Medical College of Rush University, Chicago, IL 60612, USA
J Orthop Res 20:101-7. 2002
..moments, it only accounted for about 50% of its variation, emphasizing the need for a dynamic evaluation of the knee joint loading environment...
- Gait characteristics of patients with knee osteoarthritis
K R Kaufman
Orthopedic Biomechanics Laboratory, Department of Orthopedic Surgery, MN, USA
J Biomech 34:907-15. 2001
..This difference reflects the patient's compensation to reduce the knee joint loading. Further, subjects with OA and a higher body mass index have a lower knee extensor moment...
- Creep behavior of the intact and meniscectomy knee joints
Department of Mechanical and Manufacturing Engineering, University of Calgary, 2500 University Drive, NW, Calgary, Alberta, Canada T2N 1N4
J Mech Behav Biomed Mater 4:1351-8. 2011
..This creep behavior has not been investigated in whole knee joint modeling...
- The osteoarthritis initiative: report on the design rationale for the magnetic resonance imaging protocol for the knee
C G Peterfy
Synarc Inc, San Francisco, CA 94105, USA
Osteoarthritis Cartilage 16:1433-41. 2008
..To report on the process and criteria for selecting acquisition protocols to include in the osteoarthritis initiative (OAI) magnetic resonance imaging (MRI) study protocol for the knee...
- Increased knee joint loads during walking are present in subjects with knee osteoarthritis
A J Baliunas
Department of Orthopedic Surgery, Rush Medical College of Rush University, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
Osteoarthritis Cartilage 10:573-9. 2002
..adduction moment can be used to assess the load distribution between the medial and lateral compartments of the knee joint. Additionally, this study tests if changes in the knee angles, such as a reduced midstance knee flexion angle, ..
- Correlation of power Doppler sonography with vascularity of the synovial tissue of the knee joint in patients with osteoarthritis and rheumatoid arthritis
University of Wuerzburg, Germany
Arthritis Rheum 44:331-8. 2001
..To examine the significance of power Doppler sonography (PDS) in the diagnosis of synovial hypertrophy of the knee joint by verifying and comparing the PDS findings with histopathologic findings of synovial membrane vascularity...
- Independent drilling outperforms conventional transtibial drilling in anterior cruciate ligament reconstruction
Mark E Steiner
Sports Medicine Section, Orthopaedic Department, New England Baptist Hospital, Boston, Massachusetts 02120, USA
Am J Sports Med 37:1912-9. 2009
..Optimal tunnel placement is critical in anterior cruciate ligament reconstructive surgery, yet the method used to drill the tunnels may compromise their placement...
- The effect of graft tensioning in anatomic 2-bundle ACL reconstruction on knee joint kinematics
Department of Orthopaedic Surgery, Kobe University, Graduate School of Medicine, 7 5 1 Kusunoki cho, Chuo Ku, Kobe, Hyogo, 650 0017, Japan
Knee Surg Sports Traumatol Arthrosc 15:508-14. 2007
- Synovitis: a potential predictive factor of structural progression of medial tibiofemoral knee osteoarthritis -- results of a 1 year longitudinal arthroscopic study in 422 patients
Service de Rhumatologie B, Hopital Cochin, AP HP, Universite Rene Descartes, Paris, France
Osteoarthritis Cartilage 13:361-7. 2005
..To evaluate the prevalence of synovitis in painful medial tibiofemoral knee osteoarthritis (OA) and to evaluate correlation between synovitis and the structural severity and progression of tibiofemoral cartilage damage...
- Assessment of movement-evoked pain in osteoarthritis by the knee-bend and CatWalk tests: a clinically relevant study
Institute of Histology and Embryology, Faculty of Medicine and IBMC, University of Porto, Porto, Portugal
J Pain 9:945-54. 2008
..The aim of this study was to investigate pain-related behaviors on the affected knee joint, the primary source of nociception, in animals with mono-iodoacetate-induced OA, using the knee-bend (which ..
- A brief screening tool for knee pain in primary care (KNEST). 2. Results from a survey in the general population aged 50 and over
Primary Care Sciences Research Centre, Keele University, UK
Rheumatology (Oxford) 43:55-61. 2004
..To use a brief screening tool to identify knee pain (all knee pain, non-chronic and chronic knee pain) and associated health-care use in the general population aged 50 yr and over...
- Primary care treatment of knee pain--a survey in older adults
Primary Care Musculoskeletal Research Centre, Primary Care Sciences, Keele University, Keele, Staffs ST5 5BG, UK
Rheumatology (Oxford) 46:1694-700. 2007
..To describe the treatment of knee pain in older adults in primary care and to compare reported practice with published evidence...
- A framework for the in vivo pathomechanics of osteoarthritis at the knee
Thomas P Andriacchi
Department of Mechanical Engineering, Stanford University, Division of Biomechanical Engineering, Stanford, CA 94305 4038, USA
Ann Biomed Eng 32:447-57. 2004
..The integrated in vivo framework presented here will be helpful for the interpretation of laboratory experiments as well as for the development of new methods for the evaluation of OA at the knee...
- Functional calibration procedure for 3D knee joint angle description using inertial sensors
Ecole Polytechnique Federale de Lausanne EPFL, Laboratory of Movement Analysis and Measurement, Lausanne, Switzerland
J Biomech 42:2330-5. 2009
Measurement of three-dimensional (3D) knee joint angle outside a laboratory is of benefit in clinical examination and therapeutic treatment comparison...
- Lifetime risk of symptomatic knee osteoarthritis
Business Computer Applications, Atlanta, Georgia, USA
Arthritis Rheum 59:1207-13. 2008
..To estimate the lifetime risk of symptomatic knee osteoarthritis (OA), overall and stratified by sex, race, education, history of knee injury, and body mass index (BMI)...
- Soft-tissue balancing during total knee arthroplasty in the varus knee
William M Mihalko
Adult Reconstructive Research, Department of Orthopaedic Surgery, University of Tennessee Campbell Clinic, Memphis, Tennessee 38017, USA
J Am Acad Orthop Surg 17:766-74. 2009
..balancing during total knee arthroplasty is an important step in optimizing the mechanical balance of the knee joint. Soft-tissue contractures that result from varus coronal plane deformity can pose a difficult problem, and the ..
- An intraoperatively moulded PMMA prostheses like spacer for two-stage revision of infected total knee arthroplasty
Department of Orthopaedic Surgery, Inselspital, University of Bern, Switzerland
Knee 18:464-9. 2011
..The use of this spacer is a time sparing, cheap and convenient option in 2-stage TKA revision...
- Proprioception in knee osteoarthritis: a narrative review
Reade, Centre of Rehabilitation and Rheumatology formerly Jan van Breemen Instituut, Department of Rehabilitation Research, Amsterdam, The Netherlands
Osteoarthritis Cartilage 19:381-8. 2011
..To give an overview of the literature on knee proprioception in knee osteoarthritis (OA) patients...
- A finite element model of the human knee joint for the study of tibio-femoral contact
Tammy L Haut Donahue
Department of Mechanical Engineering, Michigan Technological University, Houghton 49931, USA
J Biomech Eng 124:273-80. 2002
..the goals of this study were 1) to develop a geometrically accurate three-dimensional solid model of the knee joint with special attention given to the menisci and articular cartilage, 2) to determine to what extent bony ..
- Secondary gait changes in patients with medial compartment knee osteoarthritis: increased load at the ankle, knee, and hip during walking
Stanford University Medical Center, Stanford, California 94305 4038, USA
Arthritis Rheum 52:2835-44. 2005
..This study tested the hypothesis that gait changes related to knee osteoarthritis (OA) of varied severity are associated with increased loads at the ankle, knee, and hip...
- Involvement of Nav 1.8 sodium ion channels in the transduction of mechanical pain in a rodent model of osteoarthritis
Department of Physiology and Pharmacology, University of Calgary, 3330, Hospital Drive NW, Calgary, AB, T2N 4N1, Canada
Arthritis Res Ther 14:R5. 2012
..The present study examined whether local application of A-803467, a selective blocker of the Nav 1.8 sodium channel, can reduce nociceptive transmission from the joint in a rodent model of osteoarthritis (OA)...
- Reduced knee joint moment in ACL deficient patients at a cost of dynamic stability during landing
Kai Daniel Oberländer
Institute of Biomechanics and Orthopaedics, German Sport University Cologne, Germany
J Biomech 45:1387-92. 2012
..05) and we found a significant correlation between moment arms at the knee joint and trunk angle (r² = 0.48;p<0.01)...
- Increase in outpatient knee arthroscopy in the United States: a comparison of National Surveys of Ambulatory Surgery, 1996 and 2006
Department of Orthopaedic Surgery, University of California Davis, 4860 Y Street, Suite 3800, Sacramento, CA 95817, USA
J Bone Joint Surg Am 93:994-1000. 2011
..This study was proposed to investigate the changes in the utilization of knee arthroscopy in an ambulatory setting over the past decade in the United States as well as its implications...
- Estimation of quasi-stiffness of the human knee in the stance phase of walking
Department of Mechanical Engineering and Materials Science, School of Engineering and Applied Science, Yale University, New Haven, Connecticut, United States of America
PLoS ONE 8:e59993. 2013
..The knee joint moment-angle relationship is approximately linear in the flexion and extension stages of stance, exhibiting ..
- Inertial sensor-based knee flexion/extension angle estimation
Centre for Rehabilitation and Human Performance Research, University of Salford, UK
J Biomech 42:2678-85. 2009
A new method for estimating knee joint flexion/extension angles from segment acceleration and angular velocity data is described...
- Anterior cruciate ligament changes in the human knee joint in aging and osteoarthritis
Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA
Arthritis Rheum 64:696-704. 2012
- Evolution of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score)
D J Hunter
Rheumatology Department, Royal North Shore Hospital, Northern Clinical School, University of Sydney, Sydney, NSW 2065, Australia
Osteoarthritis Cartilage 19:990-1002. 2011
..The purpose of this report is to describe the instrument and its reliability...
- Prediction of range of motion 2 years after mobile-bearing total knee arthroplasty: PCL-retaining versus PCL-sacrificing
Ishii Orthopaedic and Rehabilitation Clinic, 1089 Shimo Oshi, Gyoda, Saitama, 361 0037, Japan
Knee Surg Sports Traumatol Arthrosc 19:2002-8. 2011
..This study evaluated the changes in the range of motion (ROM) with time postoperatively...
- Massive weight loss-induced mechanical plasticity in obese gait
Department of Exercise and Sport Science, East CarolinaUniversity, Greenville, North Carolina, USA
J Appl Physiol (1985) 111:1391-9. 2011
..There may be a weight loss threshold of 30 kg limiting changes in gait kinematics. Implications for exercise prescription are also discussed...
- Muscle and external load contribution to knee joint contact loads during normal gait
C R Winby
School of Sport Science, Exercise and Health, University of Western Australia, M408 35 Stirling Hwy, Crawley, WA 6009, Australia
J Biomech 42:2294-300. 2009
..osteoarthritis and it has been proposed that these moments increase the load on the medial compartment of the knee joint. However, this mechanism cannot be validated without taking into account the internal forces and moments ..
- Delineating the impact of obesity and its relationship on recovery after total joint arthroplasties
C A Jones
School of Public Health, University of Alberta, Edmonton, AB, Canada T6G 2G4
Osteoarthritis Cartilage 20:511-8. 2012
- Phenotypic alterations of neurons that innervate osteoarthritic joints in rats
University of Porto, Porto, Portugal
Arthritis Rheum 62:3677-85. 2010
..mechanisms of nociception in OA, we studied the expression of the phenotype markers calcitonin gene-related peptide (CGRP), isolectin B4 (IB4), and neurofilament 200 (NF200) in sensory neurons innervating the OA knee joint in rats.
- Autologous chondrocyte implantation: a systematic review
Joshua D Harris
Division of Sports Medicine Cartilage Repair Center, Department of Orthopaedics, The Ohio State University Sports Medicine Center, 2050 Kenny Road, Suite 3100, Columbus, OH 43221 3502, USA
J Bone Joint Surg Am 92:2220-33. 2010
- Does greater knee flexion increase patient function and satisfaction after total knee arthroplasty?
Brandon N Devers
Baylor College of Medicine, Houston, Texas 77030, USA
J Arthroplasty 26:178-86. 2011
..This suggests that increased knee flexion, particularly more than 130°, may lead to improved outcomes after TKA...
- Autologous platelet gel for tissue regeneration in degenerative disorders of the knee
Immunohaematology and Transfusion Medicine Unit, Cosenza Hospital, Cosenza, Italy
Blood Transfus 10:72-7. 2012
..The refinement of the use of platelet-derived growth factors that has occurred over the last decade has led to a broadening of the fields of use, in particular for new treatments in orthopaedics aimed at improving tissue regeneration...
- An EMG-driven musculoskeletal model to estimate muscle forces and knee joint moments in vivo
David G Lloyd
School of Human Movement and Exercise Science, University of Western Australia, Perth, 35 Stirling Highway, Crawley, WA 6009, Australia
J Biomech 36:765-76. 2003
..Muscle-tendon lengths and moment arms of 13 muscles crossing the knee joint were determined from joint kinematics using a three-dimensional anatomical model of the lower limb...
- A prospective, randomized clinical study of osteochondral autologous transplantation versus microfracture for the treatment of osteochondritis dissecans in the knee joint in children
Kaunas University of Medicine, Kaunas, Lithuania
J Pediatr Orthop 29:741-8. 2009
..mosaic-type osteochondral autologous transplantation (OAT) and microfracture (MF) procedures for the treatment of osteochondritis dissecans (OCD) defects of the femoral condyles of the knee joint in children under the age of 18 years.
- Definition and classification of early osteoarthritis of the knee
Frank P Luyten
Division of Rheumatology, Laboratory for Skeletal Development and Joint Disorders, Katholieke Universiteit Leuven, O and N 1, Herestraat 49, Bus 813, 3000, Leuven, Belgium
Knee Surg Sports Traumatol Arthrosc 20:401-6. 2012
..Here, classification criteria for this group of patients are presented, allowing a more defined and accurate inclusion in clinical trials in the future...
- Treatment of chondral defects of the knee with one step matrix-assisted technique enhanced by autologous concentrated bone marrow: in vitro characterisation of mesenchymal stem cells from iliac crest and subchondral bone
Laura de Girolamo
Orthopaedic Biotechnologies Lab, IRCCS Galeazzi Orthopaedic Institute, Milan, Italy
Injury 41:1172-7. 2010
..Although the AMIC(®) approach has many advantages, the surgical technique in the application of the microfracture technique remains essential and affects the final result...
- Can single limb support objectively assess the functional severity of knee osteoarthritis?
AposTherapy Research Group, Herzliya, Israel
Knee 19:32-5. 2012
..These results suggest that single-limb support quintiles may be added as an additional scale for generally assessing the symptomatic stage of KOA...
- Validity and inter-rater reliability of medio-lateral knee motion observed during a single-limb mini squat
Department of Orthopedics, Clinical Sciences Lund, Lund University, Sweden
BMC Musculoskelet Disord 11:265. 2010
..The aim was to validate an observational clinical test of assessing the medio-lateral knee motion, using a three-dimensional (3-D) motion analysis system. In addition, the inter-rater reliability was evaluated...
- An efficient subset of morphological measures for articular cartilage in the healthy and diseased human knee
Robert J Buck
StatAnswers Consulting LLC, San Diego, California 92122, USA
Magn Reson Med 63:680-90. 2010
..These variables hence define an efficient subset for describing structural status and change in osteoarthritic cartilage...
- Osteoarthritis year 2010 in review: imaging
Department of Radiology, Boston University School of Medicine, Boston, MA 02118, USA
Osteoarthritis Cartilage 19:354-60. 2011
..ongoing using conventional radiography with a focus on measurements of joint space width and alignment of the knee joint. Ultrasound is emerging as a useful imaging technique, particularly in the field of hand OA research...
- Type III collagen, a fibril network modifier in articular cartilage
Jiann Jiu Wu
Department of Orthopedics and Sports Medicine, University of Washington, Seattle, Washington 98195, USA
J Biol Chem 285:18537-44. 2010
- Effects of increasing tibial slope on the biomechanics of the knee
J Robert Giffin
Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Am J Sports Med 32:376-82. 2004
..To determine the effects of increasing anterior-posterior (A-P) tibial slope on knee kinematics and in situ forces in the cruciate ligaments...
- Treatment of anterior cruciate ligament injuries with special reference to graft type and surgical technique: an assessment of randomized controlled trials
Department of Orthopaedics, Sahlgrenska University Hospital, SE 431 80, Molndal, Sweden
Arthroscopy 25:1139-74. 2009
..The secondary aims were to identify the relative strengths and weaknesses of the selected studies, to resolve contradictions in the literature, and to evaluate the need for further studies...
- The Knee Clinical Assessment Study-CAS(K). A prospective study of knee pain and knee osteoarthritis in the general population: baseline recruitment and retention at 18 months
Primary Care Sciences Research Centre, Keele University, Keele, North Staffordshire, ST5 5BG, UK
BMC Musculoskelet Disord 7:30. 2006
..We investigated these matters in the context of baseline recruitment and retention at 18 months of participants for a prospective observational cohort study of knee pain and knee osteoarthritis in the general population...
- Does accurate anatomical alignment result in better function and quality of life? Comparing conventional and computer-assisted total knee arthroplasty
Peter F Choong
Department of Orthopaedics, St Vincent s Hospital, University of Melbourne, Melbourne, Victoria, Australia
J Arthroplasty 24:560-9. 2009
..Computer-assisted total knee arthroplasty achieves greater accuracy in implant alignment and this correlates with better knee function and improved quality of life...
- In situ compressive stiffness, biochemical composition, and structural integrity of articular cartilage of the human knee joint
Institute of Pathology, University of Bern, Bern, Switzerland
Osteoarthritis Cartilage 9:582-92. 2001
..a hand-held indentation probe has recently been developed and baseline data for macroscopically normal knee joint cartilage were provided. However, the histological stage of degeneration of the measured cartilage was not known...
- A second decade lifetable survival analysis of the Oxford unicompartmental knee arthroplasty
Andrew J Price
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK
Clin Orthop Relat Res 469:174-9. 2011
..Long-term second decade results are required to establish if the design aim can be met...
- Treatment of knee pain in older adults in primary care: development of an evidence-based model of care
Primary Care Musculoskeletal Research Centre, Primary Care Sciences, Keele University, Keele, Staffs ST5 5BG, UK
Rheumatology (Oxford) 46:638-48. 2007
..To develop a stepped model of care for the treatment of knee pain in older adults in primary care based on recommended interventions...
- Macroscopic and histopathologic analysis of human knee menisci in aging and osteoarthritis
Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA
Osteoarthritis Cartilage 19:1132-41. 2011
..The objectives of this study were to (1) establish standardized protocols for representative macroscopic and microscopic analysis, (2) improve existing scoring systems, and (3) apply these techniques to a large number of human menisci...
- Identification of passive elastic joint moments in the lower extremities
Institute of Automatic Control Engineering, Technical University of Munich, Germany
J Biomech 32:539-44. 1999
..The model can be implemented in biomechanical models of the lower extremities, which are generally used for the simulation of multi-joint movements such as standing-up, walking, running, or jumping...
- The role of ambulatory mechanics in the initiation and progression of knee osteoarthritis
Thomas P Andriacchi
Department of Mechanical Engineering, Biomechanical Engineering, Stanford University, Stanford, CA 94305, USA
Curr Opin Rheumatol 18:514-8. 2006
..This review examines recent in-vivo studies of ambulation and discusses the fundamental role of mechanics of ambulation in the initiation and progression of osteoarthritis at the knee...
- Explicit finite element modeling of total knee replacement mechanics
Jason P Halloran
University of Denver, 2390 S York, Denver, CO 80208, USA
J Biomech 38:323-31. 2005
..These analyses have shown that, at low computational cost, a force-control dynamic simulation of a gait cycle can yield useful and predictable results...
- A three-dimensional finite element analysis of the combined behavior of ligaments and menisci in the healthy human knee joint
Group of Structural Mechanics and Material Modelling, Aragon Institute of Engineering Research I3A, University of Zaragoza, Maria de Luna, 3, E 50018 Zaragoza, Spain
J Biomech 39:1686-701. 2006
..The results obtained reproduce the complex, nonuniform stress and strain fields that occur in the biological soft tissues involved and the kinematics of the human knee joint under a physiological external load.
- Muscle performance during maximal isometric and dynamic contractions is influenced by the stiffness of the tendinous structures
Institute of Sports Medicine Copenhagen Team Danmark Test Center, Bispebjerg Bakke, 23, bygn 8, Bispebjerg Hospital, 2400 Copenhagen NV, Denmark
J Appl Physiol (1985) 99:986-94. 2005
- Evidence of abnormal lower-limb torque coupling after stroke: an isometric study
Theresa Hayes Cruz
Department of Biomedical Engineering, Northwestern University, Chicago, IL, USA
Stroke 39:139-47. 2008
..Although stroke survivors often display abnormal joint torque patterns, studies of torque-coupling in the lower limb are lacking, despite their potential impact on gait abnormalities...
- Gait analysis of patients following total knee replacement: a systematic review
Jodie A McClelland
Musculoskeletal Research Centre, La Trobe University, Melbourne, Victoria 3086, Australia
Knee 14:253-63. 2007
..The substantial methodologic differences between studies may contribute to the inconsistencies in reported findings for many gait outcomes. Future research is needed to determine the clinical relevance of these findings...
- Correlation of maximum flexion with clinical outcome after total knee replacement in Asian patients
K K Park
Joint Reconstruction Center, Seoul National University, Bundang Hospital, 300 Gumi dong, Bundang gu, Seongnam si, Gyeonggi do 463 707, Seoul, Korea
J Bone Joint Surg Br 89:604-8. 2007
..Efforts to increase post-operative maximum flexion should be exercised with caution until concerns relating to high-flexion activities are sufficiently resolved...
- Decreased knee adduction moment does not guarantee decreased medial contact force during gait
Jonathan P Walter
Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, Florida, USA
J Orthop Res 28:1348-54. 2010
..93). Future studies that evaluate the effectiveness of gait modifications for offloading the medial compartment of the knee should consider the combined effect of these two knee moments...
- Tibio-femoral movement in the living knee. A study of weight bearing and non-weight bearing knee kinematics using 'interventional' MRI
Department of Orthopaedics, St Mary s Hospital, W2 1NY London, UK
J Biomech 38:269-76. 2005
- Changes in in vivo knee loading with a variable-stiffness intervention shoe correlate with changes in the knee adduction moment
Jennifer C Erhart
Department of Mechanical Engineering, Stanford University, Stanford, California, USA
J Orthop Res 28:1548-53. 2010
..The reductions in the external knee adduction moment are indicative of reductions in in vivo medial compressive force with this intervention...
- Acoustic stiffness and change in plug cartilage over time after autologous osteochondral grafting: correlation between ultrasound signal intensity and histological score in a rabbit model
Department of Orthopaedic Surgery, School of Health Sciences, Faculty of Medicine, Kyoto University, Kyoto, Japan
Arthritis Res Ther 6:R492-504. 2004
- The influence of foot progression angle on the knee adduction moment during walking and stair climbing in pain free individuals with knee osteoarthritis
Center for Biomedical Engineering Research, Department of Mechanical Engineering, University of Delaware, Newark, DE 19716, United States
Gait Posture 26:436-41. 2007
..No significant differences were noted during stair descent. These results suggest that walking with a toe-out strategy may benefit persons with early stages of medial knee OA...
- Effects of pulsed electromagnetic fields on patients' recovery after arthroscopic surgery: prospective, randomized and double-blind study
Sacro Cuore Don Calabria Hospital, Via don A Sempreboni 5, 37024 Negrar Vr, Italy
Knee Surg Sports Traumatol Arthrosc 15:830-4. 2007
..05). Treatment with I-ONE aided patient recovery after arthroscopic surgery, reduced the use of NSAIDs, and also had a positive long-term effect...
- Systematic review of single-bundle anterior cruciate ligament reconstruction outcomes: a baseline assessment for consideration of double-bundle techniques
Paul B Lewis
Division of Sports Medicine, Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA
Am J Sports Med 36:2028-36. 2008
..Challenging this comparison, however, has been the lack of an established consensus on the success of single-bundle reconstruction...
- Increased failure rate of autologous chondrocyte implantation after previous treatment with marrow stimulation techniques
Cartilage Repair Center, Brigham and Women s Hospital, Harvard Medical School, 850 Boylston Street, Chestnut Hill, MA 02467, USA
Am J Sports Med 37:902-8. 2009
..Common knowledge holds that these treatments do not compromise subsequent cartilage repair procedures with autologous chondrocyte implantation...
- Gender differences exist in the hip joint moments of healthy older walkers
Katherine A Boyer
VA Palo Alto Health Care System, Bone and Joint Rehabilitation R and D Center of Excellence, Palo Alto, CA 94304, USA
J Biomech 41:3360-5. 2008
..This is in favor of a hypothesis that the increased joint contact stress in a female population could contribute to a greater joint degeneration at the hip in females as compared with males...
- The effect of anterior cruciate ligament injury on knee joint function under a simulated muscle load: a three-dimensional computational simulation
Orthopaedic Biomechanics Laboratory, Harvard Medical School, Massachusetts General Hospital Beth Israel Deaconess Medical Center, Boston 02215, USA
Ann Biomed Eng 30:713-20. 2002
- Double-bundle ACL reconstruction can improve rotational stability
Department of Orthopaedic Surgery, Hyogo College of Medicine, Nishinomiya, Japan
Clin Orthop Relat Res 454:100-7. 2007
..However, using the new measurement system, patients with double-bundle ACL reconstruction showed better pivot shift control of complex instability than patients with anteromedial and posterolateral single-bundle reconstruction...
- A systematic review of the femoral origin and tibial insertion morphology of the ACL
Department of Orthopaedic Surgery, University of Pittsburgh, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
Knee Surg Sports Traumatol Arthrosc 17:213-9. 2009
..This study is a systematic review of the morphology of the ACL femoral origin and tibial insertion as reported in the literature...
- AQUILA: assessment of quality in lower limb arthroplasty. An expert Delphi consensus for total knee and total hip arthroplasty
Bart G Pijls
Department of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands, Albinusdreef 2, Leiden, The Netherlands
BMC Musculoskelet Disord 12:173. 2011
..A Delphi approach was used to develop a checklist for reporting quality, methodological quality and generalizability of case series and cohorts in total hip and total knee arthroplasty with a focus on aseptic loosening...
- Differential diagnosis of tumours and tumour-like lesions of the infrapatellar (Hoffa's) fat pad: pictorial review with an emphasis on MR imaging
Department of Radiology, MRI Centre, Royal Orthopaedic Hospital, Birmingham B31 2AP, UK
Eur Radiol 14:2337-46. 2004
..This pictorial review illustrates the spectrum of mass-like lesions that can affect the IFP, emphasizing the radiographic and MR findings that suggest a specific diagnosis...
- Treatment of articular cartilage lesions of the knee joint using a modified AMIC technique
Laboratorio di Chirurgia Artroscopica, Via Teodoro La Cava 36, Isernia, Italy
Knee Surg Sports Traumatol Arthrosc 18:509-13. 2010
..The collagen membrane forms the roof of a 'biological chamber', and serves to protect and contains the stem cells as they differentiate into chondrocytes, which will form a healthy regenerative cartilage...
- High tibial osteotomy for medial compartment osteoarthritis
G S E Dowd
Department of Orthopaedics, Royal Free Hospital, Pond Street, London NW3 2QG, UK
Knee 13:87-92. 2006
..An attempt has been made to incorporate important technical considerations, recent developments and other treatment options in this condition...
- Immediate effects of a controllable knee ankle foot orthosis for functional compensation of gait in patients with proximal leg weakness
Juan C Moreno
Bioengineering Group, Industrial Automation Institute of the Spanish National Research Council, CSIC, Carretera Campo Real, Madrid, Spain
Med Biol Eng Comput 46:43-53. 2008
Application of intermittent control of the knee joint stiffness in a knee ankle foot orthosis (KAFO) during gait is proposed...
- Is there a functional benefit to obtaining high flexion after total knee arthroplasty?
Robert Michael Meneghini
St Vincent Center for Joint Replacement, Indianapolis, Indiana 46260, USA
J Arthroplasty 22:43-6. 2007
..02). Obtaining flexion greater than 125 degrees after TKA does not offer a benefit in overall knee function. However, obtaining a high degree of flexion appears to optimize stair climbing...
- Joint torques and dynamic joint stiffness in elderly and young men during stepping down
Sally D Lark
Active Life Span Research, Manchester Metropolitan University, Alsager ST7 2HL, UK
Clin Biomech (Bristol, Avon) 18:848-55. 2003
..To compare the joint torque pattern and dynamic joint stiffness at the knee and ankle in elderly and young men during stepping down...
- Influence of knee flexion angle on femoral tunnel characteristics when drilled through the anteromedial portal during anterior cruciate ligament reconstruction
Department of Orthopaedic Surgery, University Hospital of Larissa, Medical School, University of Thessalia, Larissa, Greece
Arthroscopy 24:459-64. 2008
- Risk factors for a contralateral anterior cruciate ligament injury
Department of Orthopaedics, Lund University and Lund University Hospital, 221 85 Lund, Sweden
Knee Surg Sports Traumatol Arthrosc 18:277-91. 2010
..This literature review indicates that the increased risk of sustaining a contralateral ACL injury should be contemplated, when considering the return to a high level of activity after an ACL injury...
- The microfracture technique for the treatment of full-thickness articular cartilage lesions of the knee: midterm results
Medical Faculty of Istanbul, University of Istanbul, Istanbul, Turkey
Arthroscopy 24:1214-20. 2008
..The purpose of this study was to determine the effectiveness of the microfracture technique in the treatment of full-thickness articular cartilage lesions of the knee...
- Quantitative T2 mapping of knee cartilage: differentiation of healthy control cartilage and cartilage repair tissue in the knee with unloading--initial results
Tallal C Mamisch
Department of Orthopedic Surgery, University of Berne, Berne, Switzerland
Radiology 254:818-26. 2010
..on T2 cartilage maps the effect of unloading during a clinical magnetic resonance (MR) examination in the postoperative follow-up of patients after matrix-associated autologous chondrocyte transplantation (MACT) of the knee joint.
- Active and passive contributions to joint kinetics during walking in older adults
Department of Biomedical Engineering, University of Wisconsin Madison, Madison, WI 53706, USA
J Biomech 41:1520-7. 2008
..The results of this study suggest that age-related shifts in joint kinetics do not arise as a result of increased passive hip joint stiffness, but seem to be reflected in plantar-flexor weakness...