temporal bone

Summary

Top Publications

  1. ncbi Development and evaluation of an improved cochlear implant electrode design for electric acoustic stimulation
    Oliver Adunka
    ENT Department, J W Goethe University Frankfurt am Main, Frankfurt am Main, Germany
    Laryngoscope 114:1237-41. 2004
  2. doi Analysis of Vibrant Soundbridge placement against the round window membrane in a human cadaveric temporal bone model
    Ronald J E Pennings
    Division of Otolaryngology, Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
    Otol Neurotol 31:998-1003. 2010
  3. ncbi Management outcomes following lateral temporal bone resection for ear and temporal bone malignancies
    Michael G Moore
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Otolaryngol Head Neck Surg 137:893-8. 2007
  4. pmc Endoscopy-assisted transoral resection of the styloid process in Eagle's syndrome. Case report
    Fumihiko Matsumoto
    Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Head Face Med 8:21. 2012
  5. pmc Clinical validation of percutaneous cochlear implant surgery: initial report
    Robert Frederick Labadie
    Department of Otolaryngology Head and Neck Surgery, Vanderbilt University, Nashville, Tennessee 37232 8605, USA
    Laryngoscope 118:1031-9. 2008
  6. ncbi Branchio-oto-renal syndrome: detection of EYA1 and SIX1 mutations in five out of six Danish families by combining linkage, MLPA and sequencing analyses
    Kirsten Marie Sanggaard
    Wilhelm Johannsen Centre for Functional Genome Research, Section of Genetics, Institute of Cellular and Molecular Medicine, The Panum Institute, University of Copenhagen, Copenhagen, Denmark
    Eur J Hum Genet 15:1121-31. 2007
  7. ncbi Three-dimensional modeling of middle ear biomechanics and its applications
    Rong Z Gan
    Hough Ear Institute, 3400 NW 56th Street, Oklahoma City, OK 73112, U S A
    Otol Neurotol 23:271-80. 2002
  8. ncbi The outcome of radical surgery and postoperative radiotherapy for squamous carcinoma of the temporal bone
    David A Moffat
    Department of Otoneurological and Skull Base Surgery, Addenbrooke s Cambridge University Teaching Hospital NHS Trust, Cambridge CB2 2QQ, UK
    Laryngoscope 115:341-7. 2005
  9. doi Minimally invasive computer-assisted approach for cochlear implantation: a human temporal bone study
    Yann Nguyen
    INSERM, UMR S 867, Paris, France
    Surg Innov 18:259-67. 2011
  10. ncbi Age-related histopathologic changes in the human cochlea: a temporal bone study
    Takeshi Kusunoki
    International Hearing Foundation, Minneapolis, Minnesota, USA
    Otolaryngol Head Neck Surg 131:897-903. 2004

Research Grants

  1. Human middle-ear imaging, physiology, and biomechanics
    CHARLES RICHARD STEELE; Fiscal Year: 2013
  2. CLONING OF THE Hol MUTATION
    Licia Selleri; Fiscal Year: 2009
  3. Ossicle vibration measurements in conductive hearing loss
    Steven L Jacques; Fiscal Year: 2013
  4. Microscopy in the cochlea
    Mark J Schnitzer; Fiscal Year: 2011
  5. Drosophila model for noise-induced hearing loss
    Daniel F Eberl; Fiscal Year: 2012
  6. The Otopathology of Hearing Loss: Genotype-Phenotype Correlation in Human TB
    Fred H Linthicum; Fiscal Year: 2013
  7. Optopathology by Light Microscopy and Molecular Techniques
    Michael J McKenna; Fiscal Year: 2013
  8. Otopathology by Light Microscopy and Molecular Techniques
    Saumil N Merchant; Fiscal Year: 2010
  9. Modern Studies of the Human Temporal Bone
    AKIRA NONE ISHIYAMA; Fiscal Year: 2010
  10. OTITIS MEDIA RESEARCH CENTER
    Charles Bluestone; Fiscal Year: 1990

Detail Information

Publications342 found, 100 shown here

  1. ncbi Development and evaluation of an improved cochlear implant electrode design for electric acoustic stimulation
    Oliver Adunka
    ENT Department, J W Goethe University Frankfurt am Main, Frankfurt am Main, Germany
    Laryngoscope 114:1237-41. 2004
    ..Special emphasis was placed on the practicality for combined electric and acoustic stimulation of the auditory system...
  2. doi Analysis of Vibrant Soundbridge placement against the round window membrane in a human cadaveric temporal bone model
    Ronald J E Pennings
    Division of Otolaryngology, Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
    Otol Neurotol 31:998-1003. 2010
    ..To evaluate optimal placement of the Floating Mass Transducer of the Vibrant Soundbridge (Med-El, Innsbruck, Austria) against the round window membrane, particularly the impact of interposed coupling fascia and of covering materials...
  3. ncbi Management outcomes following lateral temporal bone resection for ear and temporal bone malignancies
    Michael G Moore
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Otolaryngol Head Neck Surg 137:893-8. 2007
    To evaluate clinical outcomes following lateral temporal bone resection (LTBR) for management of malignancies involving the ear or temporal bone.
  4. pmc Endoscopy-assisted transoral resection of the styloid process in Eagle's syndrome. Case report
    Fumihiko Matsumoto
    Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Head Face Med 8:21. 2012
    ..Endoscopy provides clear surgical view thus lessen the chance of neurovascular injury and other intraoperative complications. Endoscopy-assisted transoral resection is an optional alternative surgical procedure for Eagle's syndrome...
  5. pmc Clinical validation of percutaneous cochlear implant surgery: initial report
    Robert Frederick Labadie
    Department of Otolaryngology Head and Neck Surgery, Vanderbilt University, Nashville, Tennessee 37232 8605, USA
    Laryngoscope 118:1031-9. 2008
    ..We sought to clinically validate this technique in patients undergoing traditional cochlear implant surgery...
  6. ncbi Branchio-oto-renal syndrome: detection of EYA1 and SIX1 mutations in five out of six Danish families by combining linkage, MLPA and sequencing analyses
    Kirsten Marie Sanggaard
    Wilhelm Johannsen Centre for Functional Genome Research, Section of Genetics, Institute of Cellular and Molecular Medicine, The Panum Institute, University of Copenhagen, Copenhagen, Denmark
    Eur J Hum Genet 15:1121-31. 2007
    ..The present, yet preliminary, observation that renal and temporal bone malformations are less frequent in SIX1-related disease suggests a slightly different clinical profile ..
  7. ncbi Three-dimensional modeling of middle ear biomechanics and its applications
    Rong Z Gan
    Hough Ear Institute, 3400 NW 56th Street, Oklahoma City, OK 73112, U S A
    Otol Neurotol 23:271-80. 2002
    ....
  8. ncbi The outcome of radical surgery and postoperative radiotherapy for squamous carcinoma of the temporal bone
    David A Moffat
    Department of Otoneurological and Skull Base Surgery, Addenbrooke s Cambridge University Teaching Hospital NHS Trust, Cambridge CB2 2QQ, UK
    Laryngoscope 115:341-7. 2005
    The objective was to analyze the clinical data and outcome of all the patients treated surgically for squamous carcinoma of the temporal bone in a tertiary referral department of skull base surgery over a 20-year period.
  9. doi Minimally invasive computer-assisted approach for cochlear implantation: a human temporal bone study
    Yann Nguyen
    INSERM, UMR S 867, Paris, France
    Surg Innov 18:259-67. 2011
    ..Five temporal bone specimens, with 4 titanium screws placed in the mastoid cortex, were studied...
  10. ncbi Age-related histopathologic changes in the human cochlea: a temporal bone study
    Takeshi Kusunoki
    International Hearing Foundation, Minneapolis, Minnesota, USA
    Otolaryngol Head Neck Surg 131:897-903. 2004
    ..Previous reports on aging of human cochlea included subjects with ear diseases or ototoxic drugs. We studied spiral ganglion cells, hair cells, and lateral wall of cochlea from subjects without ear disease or ototoxic drugs...
  11. pmc Outcomes following temporal bone resection
    Nichole R Dean
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Laryngoscope 120:1516-22. 2010
    To evaluate survival outcomes in patients undergoing temporal bone resection.
  12. ncbi A new classification for cochleovestibular malformations
    Levent Sennaroglu
    Department of Otolaryngology Head and Neck Surgery, Hacettepe University, Ankara, Turkey
    Laryngoscope 112:2230-41. 2002
    ..The report proposes a new classification system for inner ear malformations, based on radiological features of inner ear malformations reviewed in 23 patients...
  13. doi Utility of temporal bone computed tomographic measurements in the evaluation of inner ear malformations
    Judy L Chen
    Department of Otolaryngology Head and Neck Surgery, Stanford University, Palo Alto, CA 94305 5328, USA
    Arch Otolaryngol Head Neck Surg 134:50-6. 2008
    ..To investigate whether normative inner ear measurements can assist in the evaluation of sensorineural hearing loss (SNHL)...
  14. ncbi Two temporal bone computed tomography measurements increase recognition of malformations and predict sensorineural hearing loss
    Derk D Purcell
    Department of Radiology, University of California at San Francisco, San Francisco, CA, USA
    Laryngoscope 116:1439-46. 2006
    ..The objectives of this prospective study were to assess the reproducibility of the measurements of the cochlea and lateral semicircular canal (LSCC) and to determine if abnormal measurements predict sensorineural hearing loss (SNHL)...
  15. ncbi Temporal bone fractures: traditional classification and clinical relevance
    Stacey L Ishman
    Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, U S A
    Laryngoscope 114:1734-41. 2004
    The objectives were to evaluate the clinical relevance of traditional temporal bone radiographic descriptors and to investigate the efficacy of an alternative fracture classification scheme.
  16. ncbi Correlation between microtia and temporal bone malformation evaluated using grading systems
    Shin Ichi Ishimoto
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Arch Otolaryngol Head Neck Surg 131:326-9. 2005
    To evaluate the relationships between temporal bone abnormalities and the severity of microtia in Japanese patients using objective grading systems.
  17. ncbi The visible ear: a digital image library of the temporal bone
    Mads S Sørensen
    Department of Otolaryngology, Head and Neck Surgery, Rigshospitalet, Denmark
    ORL J Otorhinolaryngol Relat Spec 64:378-81. 2002
    High-fidelity computer-based modeling, simulation and visualization systems for the study of temporal bone anatomy and training for middle ear surgery are based on a sequence of digital anatomical images, which must cover a large tissue ..
  18. ncbi Flat-panel volume computed tomography for cochlear implant electrode array examination in isolated temporal bone specimens
    Soenke H Bartling
    Department of Neuroradiology, Hannover Medical School, Hannover, and Department of Diagnostic Radiology, Goettingen University Hospital, Goettingen, Germany
    Otol Neurotol 27:491-8. 2006
    ..Flat-panel based volume computed tomography could improve cochlear implant electrode evaluation in comparison with multislice computed tomography...
  19. doi Diffusion-weighted magnetic resonance imaging of the temporal bone
    B De Foer
    Department of Radiology, GZA Hospitals Sint Augustinus, Oosterveldlaan 24, Wilrijk Antwerp, Belgium
    Neuroradiology 52:785-807. 2010
    This paper summarizes the value of diffusion-weighted magnetic resonance imaging in the evaluation of temporal bone pathology...
  20. ncbi History of Meniere's disease and its clinical presentation
    Fernando Mancini
    Department of Otolaryngology, Ospedale Koelliker, Corso G Ferraris, 251, 10134 Torino, Italy
    Otolaryngol Clin North Am 35:565-80. 2002
    ..It seems reasonable to explain symptoms of Meniere's disease on the basis of mechanical factors (as observed in temporal bone studies) associated with biologic and biochemical factors.
  21. ncbi Hearing loss associated with enlarged vestibular aqueduct and Mondini dysplasia is caused by splice-site mutation in the PDS gene
    Jiann jou Yang
    Genetics Laboratory and Department of Life Sciences, Chung Shan Medical University, No 110, Sec 1, Chien Kuo N Road, Taichung 402, Taiwan, ROC
    Hear Res 199:22-30. 2005
    ..mutations of PDS gene are the common causes of Pendred syndrome and non-syndromic hearing loss associated with temporal bone abnormalities ranging from isolated enlargement of the vestibular aqueduct (EVA) to Mondini dysplasia...
  22. ncbi Fibrous dysplasia involving the skull base and temporal bone
    L R Lustig
    Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University, JHOC Sixth Floor, 601 N Caroline St, Baltimore, MD 21287 0910, USA
    Arch Otolaryngol Head Neck Surg 127:1239-47. 2001
    ..To gain a broader appreciation of the clinical presentation, operative treatment, and outcome of patients with fibrous dysplasia involving the skull base...
  23. ncbi Preservation of basal inner ear structures in cochlear implantation
    Oliver Adunka
    ENT Department, J W Goethe University, Frankfurt am Main, Germany
    ORL J Otorhinolaryngol Relat Spec 66:306-12. 2004
    ....
  24. ncbi A model for cochlear implant electrode insertion and force evaluation: results with a new electrode design and insertion technique
    J Thomas Roland
    Department of Otolaryngology and Neurosurgery, New York University School of Medicine, 550 First Avenue, New York, NY 10016, U S A
    Laryngoscope 115:1325-39. 2005
    ..In addition, this study should serve to present a novel model for cochlear implant electrode insertion evaluations...
  25. ncbi Reliability of the Welling scale (WS1) for rating temporal bone dissection performance
    Nancy N Butler
    Department of Otolaryngology Head and Neck Surgery, The Ohio State University College of Medicine, Columbus, Ohio, USA
    Laryngoscope 117:1803-8. 2007
    To determine the inter- and intrarater reliability of using a new scale (Welling scale) for resident evaluation of temporal bone dissection performance.
  26. pmc Anatomy of the round window and hook region of the cochlea with implications for cochlear implantation and other endocochlear surgical procedures
    Peter M M C Li
    Department of Otology and Laryngology, Harvard Medical School Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Otol Neurotol 28:641-8. 2007
    ..The goal of this study was to create a three-dimensional model of the anatomy of the hook region to identify the optimal site for cochleostomy in cochlear implant surgery...
  27. ncbi Cellular changes of Reissner's membrane in Meniere's disease: human temporal bone study
    Sebahattin Cureoglu
    Department of Otolaryngology, Otitis Media Research Center, University of Minnesota, Minneapolis, USA
    Otolaryngol Head Neck Surg 130:113-9. 2004
    ....
  28. doi Expression of the tumour-suppressor maspin in temporal bone carcinoma
    Gino Marioni
    Otolaryngology Section, Department of Neurosciences, Padova University, Padova, Italy
    Histopathology 63:242-9. 2013
    Although it accounts for fewer than 0.2% of all head and neck tumours, temporal bone squamous cell carcinoma (SCC) is an aggressive malignancy with a poor prognosis in advanced cases...
  29. ncbi Topographical anatomy and measurements of selected parameters of the rat temporal bone
    J Wysocki
    Clinic of Otolaryngology, Medical University of Warsaw, Kajetany, Poland
    Folia Morphol (Warsz) 67:111-9. 2008
    ..12 black rats a systematic anatomical description was made and measurements of selected size parameters of the temporal bone were taken...
  30. doi Variational anatomy of the human cochlea: implications for cochlear implantation
    Elsa Erixon
    Department of Otorhinolaryngology, University of Uppsala, Uppsala, Sweden
    Otol Neurotol 30:14-22. 2009
    ..To study variations in human cochlea anatomy with potential implications for cochlear implantation surgery...
  31. ncbi Morphological changes in the internal structure of the articular eminence of the temporal bone during growth from deciduous to early mixed dentition
    Jun Ichikawa
    Department of Anatomy, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
    J Biomech 40:3541-7. 2007
    ..These results suggest that the morphology of the trabecular bone was altered to adapt to the functional growth progressed from the deciduous to the early mixed dentition...
  32. doi Active middle ear implant application in case of stapes fixation: a temporal bone study
    Arnaud Deveze
    Department of Physiology and Biophysics, School of Medicine, University of Colorado Denver, Aurora, Colorado 80045, U S A
    Otol Neurotol 31:1027-34. 2010
    ..Driving the oval window directly with an active middle ear implant (AMEI) can produce high levels of input to the inner ear...
  33. doi Prognostic factors for squamous cell carcinoma of the temporal bone: extensive bone involvement or extensive soft tissue involvement?
    Makoto Ito
    Department of Otolaryngology Head and Neck Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa University Hospital, 13 1 Takaramachi, Kanazawa, Ishikawa, Japan
    Acta Otolaryngol 129:1313-9. 2009
    Extensive bone erosion correlated with a worse prognosis of the squamous cell carcinoma (SCC) of the temporal bone but extensive soft tissue involvement did not correlate with prognosis in this study...
  34. doi Squamous cell carcinoma of the temporal bone
    Paul W Gidley
    Department of Head and Neck Surgery, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Laryngoscope 120:1144-51. 2010
    To study the survival outcomes of patients with squamous cell carcinoma (SCC) of the temporal bone. A secondary purpose was to evaluate the University of Pittsburgh staging system as a predictor of survival.
  35. ncbi Middle-ear mechanics of Type III tympanoplasty (stapes columella): I. Experimental studies
    Ritvik P Mehta
    Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Otol Neurotol 24:176-85. 2003
    To investigate the mechanics of Type III tympanoplasty by developing a cadaveric temporal bone model.
  36. pmc Creating a cross-institutional grading scale for temporal bone dissection
    Dinah Wan
    Ohio State University College of Medicine, Columbus, Ohio, USA
    Laryngoscope 120:1422-7. 2010
    ..University, have pursued standardized criteria to rate their trainees' performance in the initial steps of temporal bone dissection (complete mastoidectomy with facial recess approach)...
  37. ncbi Computed tomography of the inner ear: size of anatomical structures in the normal temporal bone and in the temporal bone of patients with Menière's disease
    Gabriele A Krombach
    Department of Diagnostic Radiology, University Hospital, University of Technology RWTH Aachen, Pauwelsstrasse 30, 52074, Aachen, Germany
    Eur Radiol 15:1505-13. 2005
    ..CT images of the temporal bone of 67 patients without inner ear pathology and 53 patients with Menière's disease have been evaluated...
  38. ncbi Major and minor temporal bone abnormalities in children with and without congenital sensorineural hearing loss
    John E McClay
    Department of Otolaryngology Head and Neck Surgery, The University of Texas at Southwestern, 5323 Harry Hines Blvd, Dallas, TX 73235 9035, USA
    Arch Otolaryngol Head Neck Surg 128:664-71. 2002
    To determine the extent of correlation between sensorineural hearing loss (SNHL) and abnormal temporal bone anatomy in children.
  39. ncbi Squamous cell carcinoma of the temporal bone: a radiographic-pathologic correlation
    M B Gillespie
    Department of Otolaryngology-Head and Neck Surgery, The Medical University of South Carolina, USA
    Arch Otolaryngol Head Neck Surg 127:803-7. 2001
    ..the utility of a previously proposed staging system for patients with primary squamous cell carcinoma of the temporal bone. METHODS: Retrospective chart review of 15 patients treated for squamous cell carcinoma of the temporal bone ..
  40. pmc Predictors of survival and recurrence after temporal bone resection for cancer
    Luc G T Morris
    Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Head Neck 34:1231-9. 2012
    The purpose of this study was to identify factors predictive of outcome in patients undergoing temporal bone resection (TBR) for head and neck cancer.
  41. ncbi Temporal bone and lateral skull base malignancy: experience and results with 81 patients
    S Manolidis
    The Bobby R Alford Department of Otolaryngology, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Otol 19:S1-15. 1998
    ..Cranial nerve deficits and complications are frequent. The success rate of treatment is dependent on histology and disease extent...
  42. doi Temporal bone histopathological features of a worker who received high doses of radiation in a criticality accident: a case report
    Kimitaka Kaga
    National Institute of Sensory Organs, Department of Research Laboratory, National Tokyo Medical Center, Japan
    Acta Otolaryngol 131:451-5. 2011
    ..The third worker is in a healthy condition. We report on the temporal bone histopathological features of the second worker...
  43. ncbi High resolution micro-CT scanning as an innovative tool for evaluation of the surgical positioning of cochlear implant electrodes
    A Postnov
    Department of Physics, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium
    Acta Otolaryngol 126:467-74. 2006
    ..technique can greatly aid in design and development of new cochlear implant electrodes and is applicable for temporal bone studies...
  44. doi Sensorineural hearing loss: there is no correlation with isolated dysplasia of the lateral semi-circular canal on temporal bone CT
    Koji Yamashita
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Maidashi, Higashi ku, Fukuoka, Japan
    Acta Radiol 52:229-33. 2011
    ..Inner ear malformations may cause sensorineural hearing loss (SNHL). However, the correlation between the small lateral semi-circular canal (LSCC) and SNHL is controversial...
  45. ncbi New approach for 3D imaging and geometry modeling of the human inner ear
    U Vogel
    Fraunhofer Institute for Microelectronic Circuits and Systems IMS2, Dresden, Germany
    ORL J Otorhinolaryngol Relat Spec 61:259-67. 1999
    ..Here a new approach is presented which allows 3D imaging of temporal bone specimens with intact regions of interest and spatial resolution currently in the 10-microm range, but ..
  46. ncbi Rare temporal bone pathology of the Singa calvaria from Sudan
    F Spoor
    Department of Anatomy and Developmental Biology, University College London, United Kingdom
    Am J Phys Anthropol 107:41-50. 1998
    ..Now computed tomography (CT) has revealed that the right temporal bone lacks the structures of the bony labyrinth...
  47. ncbi Temporal bone study of development of the organ of Corti: correlation between auditory function and anatomical structure
    A G Bibas
    UCL Ear Institute, Royal Free and University College London Medical School, London, UK
    J Laryngol Otol 122:336-42. 2008
    ..To study the development of the organ of Corti in the human cochlea, and to correlate our findings with the onset of auditory function...
  48. ncbi Sound- and/or pressure-induced vertigo due to bone dehiscence of the superior semicircular canal
    L B Minor
    Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21203 6402, USA
    Arch Otolaryngol Head Neck Surg 124:249-58. 1998
    ..To describe anatomical findings and outcome in 2 patients undergoing plugging of the superior semicircular canal for treatment of these symptoms...
  49. doi Improving temporal bone dissection using self-directed virtual reality simulation: results of a randomized blinded control trial
    Yi Chen Zhao
    Department of Otolaryngology, University of Melbourne, Victoria, Australia
    Otolaryngol Head Neck Surg 144:357-64. 2011
    ..This study aims to determine whether there are any differences in performance of cadaver temporal bone dissections between novices who received traditional teaching methods and those who received unsupervised self-..
  50. ncbi Temporal bone findings on computed tomography imaging in branchio-oto-renal syndrome
    Evan J Propst
    Department of Otolaryngology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Laryngoscope 115:1855-62. 2005
    To describe temporal bone findings using visual inspection and direct measurement on computerized tomography (CT) in individuals with branchio-oto-renal syndrome (BOR)...
  51. ncbi Temporal bone erosion in patients with chronic suppurative otitis media
    E Yorgancilar
    Department of Otorhinolaryngology and Head and Neck Surgery, Dicle University School of Medicine, Diyarbakir, Turkey
    B-ENT 9:17-22. 2013
    To analyse temporal bone erosion sites (including scutum, labyrinth, facial canal, mastoid tegmen, posterior fossa dural plate and sigmoid sinus plate) in patients with chronic suppurative otitis media (CSOM).
  52. ncbi Digital volume tomography: radiologic examinations of the temporal bone
    Carsten V Dalchow
    Department of Otolaryngology, Head and Neck Surgery, Philipps University Marburg, Deutschhausstr 3, 35037 Marburg, Germany
    AJR Am J Roentgenol 186:416-23. 2006
    We evaluated the clinical applicability and the value of digital volume tomography for visualization of the lateral skull base using temporal bone specimens.
  53. ncbi Three-dimensional stapes footplate motion in human temporal bones
    Naohito Hato
    Division of Otolaryngology Head and Neck Surgery, Stanford University School of Medicine, Palo Alto, Calif, USA
    Audiol Neurootol 8:140-52. 2003
    ..Five microsphere reflective targets were placed on the stapes footplate in ten fresh human cadaver temporal bone preparations, and their vibration measured through an extended facial recess approach using a laser Doppler ..
  54. doi Inadequate acoustical temporal bone window in patients with a transient ischemic attack or minor stroke: role of skull thickness and bone density
    Annemarie D Wijnhoud
    Department of Neurology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Ultrasound Med Biol 34:923-9. 2008
    ..In some patients, especially elderly women, TCD cannot be performed because of temporal bone window failure (WF)...
  55. ncbi Quantitative analysis of Neanderthal temporal bone morphology using three-dimensional geometric morphometrics
    Katerina Harvati
    Department of Anthropology, New York University, New York, New York 10003, USA
    Am J Phys Anthropol 120:323-38. 2003
    The temporal bone is the location of several traits thought to differentiate Neanderthals from modern humans, including some proposed Neanderthal-derived traits...
  56. doi Survival outcomes in surgical treatment of 72 cases of squamous cell carcinoma of the temporal bone
    Fang Lu Chi
    Department of Otology and Skull Base Surgery, Eye and ENT Hospital, Fudan University, Shanghai, People s Republic of China
    Otol Neurotol 32:665-9. 2011
    To evaluate surgical outcomes for squamous cell carcinoma of the temporal bone.
  57. ncbi Application of a rapid-prototyped temporal bone model for surgical planning
    Mamoru Suzuki
    Department of Otolaryngology, Tokyo Medical University, Tokyo, Japan
    Acta Otolaryngol 125:29-32. 2005
    ..This 3D prototyped model constructed using a selective laser sintering method serves as a good material for surgical simulation of a malformed ear...
  58. doi Evidence-based surgical management of T1 or T2 temporal bone malignancies
    Ting Zhang
    Department of Otology and Skull Base Surgery, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China
    Laryngoscope 123:244-8. 2013
    To determine whether aggressive surgical management is more effective than local canal resection (LCR) for early-stage temporal bone malignancies.
  59. doi [The temporal bone of lamb and pig as an alternative in ENT-education]
    A Gurr
    Klinik fur Hals, Nasen, Ohrenheilkunde, Kopf, und Halschirurgie der Ruhr Universität Bochum, St Elisabeth Hospital, Bochum
    Laryngorhinootologie 89:17-24. 2010
    Usually temporal bone dissections are done with human temporal bones. Unfortunately human donors are rare. The analysis of animals' ear morphology might help to improve the quality of surgical training.
  60. doi Management of temporal bone meningo-encephalocoele
    K K Ramalingam
    Institute of ENT and Head and Neck, KKR ENT Hospital and Research Institute, Chennai, India
    J Laryngol Otol 122:1168-74. 2008
    Meningo-encephalocoele of the temporal bone, also known as fungus cerebri, is a rare occurrence in clinical practice. We present a series of 13 patients with chronic otitis media who suffered brain herniation into the mastoid cavity...
  61. doi Completely-in-the-canal magnet-drive hearing device: a temporal bone study
    Hossein Mahboubi
    Division of Neurotology and Skull Base Surgery, Department of Otolaryngology Head and Neck Surgery, University of California, Irvine, CA 92868, USA
    Otolaryngol Head Neck Surg 148:466-8. 2013
    ..A cadaveric temporal bone was prepared. The MHD was coupled to a nickel-epoxy pellet glued to the umbo. Frequency sweeps between 0...
  62. doi Temporal bone imaging: comparison of flat panel volume CT and multisection CT
    O Majdani
    Department of Otolaryngology, Hannover Medical School, Hannover, Germany
    AJNR Am J Neuroradiol 30:1419-24. 2009
    ....
  63. ncbi Spontaneous meningoencephalic herniation of the temporal bone: case series with recommended treatment
    John K Mayeno
    Kaise Permanente Head and Neck Surgery Residency Program, Oakland, California 91402 5497, USA
    Otolaryngol Head Neck Surg 130:486-9. 2004
  64. ncbi Cochlear implantation in children with congenital inner ear malformations
    Craig A Buchman
    W Paul Biggers, MD, Carolina Children s Communication Disorders Program, Department of Otolaryngology Head and Neck Surgery, University of North Carolina, Chapel Hill, North Carolina, 27599 7600, USA
    Laryngoscope 114:309-16. 2004
    ..To assess the audiologic and surgical outcomes for pediatric cochlear implant patients with inner ear malformations...
  65. doi Three-dimensional modeling of the temporal bone for surgical training
    David Bakhos
    Service d ORL et Chirurgie Cervico Faciale, Tours, France
    Otol Neurotol 31:328-34. 2010
    The anatomy of the temporal bone (TB) can only be mastered by repeated surgical and anatomic dissections, and surgical teaching initiative had a major effect on outcomes...
  66. pmc Vestibular system changes in sudden deafness with and without vertigo: a human temporal bone study
    Taro Inagaki
    Department of Otolaryngology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Otol Neurotol 33:1151-5. 2012
    ..To investigate the vestibular system changes in sudden deafness with vertigo (SDwV) and sudden deafness without vertigo (SDwoV) and the cause of persistent canal paresis (CP) in SDwV patients...
  67. ncbi Nodal disease in temporal bone squamous carcinoma
    Alessandra Rinaldo
    Department of Surgical Sciences, ENT Clinic, University of Udine, Udine, Italy
    Acta Otolaryngol 125:5-8. 2005
  68. ncbi A new implantable middle ear hearing device for mixed hearing loss: A feasibility study in human temporal bones
    Alexander M Huber
    Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of Zurich, Switzerland
    Otol Neurotol 27:1104-9. 2006
    ..To assess the feasibility of a new, active middle ear device in temporal bones (TB)...
  69. ncbi Goldenhar's syndrome: congenital hearing deficit of conductive or sensorineural origin? Temporal bone histopathologic study
    A W Scholtz
    Department of Otolaryngology, University of Innsbruck, Innsbruck, Austria
    Otol Neurotol 22:501-5. 2001
    ....
  70. pmc Selective inner hair cell loss in prematurity: a temporal bone study of infants from a neonatal intensive care unit
    Monica Amatuzzi
    Department of Otorhinolaryngology, Universidade de Sao Paulo, Brazil
    J Assoc Res Otolaryngol 12:595-604. 2011
    ..the full-term babies (27% vs. 3%, respectively). The findings suggest that a common cause of non-genetic auditory neuropathy is selective loss of inner hair cells rather than primary damage to the cochlear nerve...
  71. doi Third windows as a cause of failure in hearing gain after exploratory tympanotomy
    Sang Cheol Kim
    Department of Otorhinolaryngology, Yonsei University College of Medicine, Seodaemun gu, Seoul, South Korea
    Otolaryngol Head Neck Surg 145:303-8. 2011
    ..It has recently been reported that pathologic third windows in inner ears can cause ABGs. Therefore, the authors conducted this study to evaluate the inner ear anatomical problems of patients who had undergone ET...
  72. doi Can virtual reality simulator be used as a training aid to improve cadaver temporal bone dissection? Results of a randomized blinded control trial
    Yi C Zhao
    Department of Otolaryngology, The University of Melbourne, Victoria, Australia
    Laryngoscope 121:831-7. 2011
    This study aims to determine whether there are improved performances in cadaver temporal bone dissection after training using a VR simulator as a teaching aid compared with traditional training methods
  73. ncbi Development of the first force-controlled robot for otoneurosurgery
    Philipp A Federspil
    Department of Otolaryngology Head and Neck Surgery, University of Saarland, Kirrberger Strasse, D 66421 Homburg Saar, Germany
    Laryngoscope 113:465-71. 2003
    ..In some surgical specialties (eg, orthopedics), robots are already used in the operating room for bony milling work. Otological surgery and otoneurosurgery may also greatly benefit from the enhanced precision of robotics...
  74. doi Three-dimensional representation of the human cochlea using micro-computed tomography data: presenting an anatomical model for further numerical calculations
    Katharina Braun
    Department of Otorhinolaryngology, Technical University Munich, Germany
    Acta Otolaryngol 132:603-13. 2012
    ....
  75. doi Comparison of round-window membrane mechanics before and after experimental stapedotomy
    Jarosław Wysocki
    Department of Otolaryngology and Rehabilitation, 2nd Faculty of Medicine, Medical University of Warsaw, Nadarzyn, Poland
    Laryngoscope 121:1958-64. 2011
    ..In the case of stapedotomy, the majority of patients report lack of satisfactory results for frequencies above 2,000 Hz. The effect has not been experimentally investigated yet...
  76. ncbi [Methods for evaluation of perimodiolar ci electrode arrays in human temporal bones]
    B Richter
    Sektion Phoniatrie und Pädaudiologie der HNO Universitätsklinik Freiburg
    Laryngorhinootologie 84:42-50. 2005
    ....
  77. doi Metachronous inflammatory myofibroblastic tumour in the temporal bone: case report
    B S Goh
    Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
    J Laryngol Otol 123:1184-7. 2009
    We report an extremely rare case of metachronous inflammatory myofibroblastic tumour in the temporal bone.
  78. ncbi The thin sectional anatomy of the temporal bone correlated with multislice spiral CT
    Junping Zhen
    Shandong University, Jinan, Shandong, China
    Surg Radiol Anat 29:409-18. 2007
    The aim of this study was to explore the method for obtaining the thin sectional anatomy data of the adult temporal bone and study the fine structures using this method...
  79. doi Spontaneous meningoencephalocele of the temporal bone: clinical spectrum and presentation
    Zayna Nahas
    Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins Hospital, 601 N Caroline St, JHOC 6251, Baltimore, MD 21287 0910, USA
    Arch Otolaryngol Head Neck Surg 134:509-18. 2008
    To describe the clinical presentation and the radiological and surgical findings in patients with spontaneous meningoencephalocele of the temporal bone.
  80. ncbi Langerhans' cell histiocytosis: temporal bone involvement
    G Marioni
    Department of Otolaryngology Head and Neck Surgery, University of Padua, Padua, Italy
    J Laryngol Otol 115:839-41. 2001
    In Langerhans' cell histiocytosis, radiological findings on temporal bone involvement show destructive bone lesions involving the mastoid, with the squamous part and middle ear less affected...
  81. doi Wideband energy reflectance measurements of ossicular chain discontinuity and repair in human temporal bone
    M Patrick Feeney
    Department of Otolaryngology, Head and Neck Surgery, University of Washington, Virginia Merrill Bloedel Hearing Research Center, Seattle, Washington 98195, USA
    Ear Hear 30:391-400. 2009
    ..The purpose of this study was to examine the use of wideband ER in the evaluation of an ossicular discontinuity and its repair in human cadaver temporal bones...
  82. ncbi Inflammatory pseudotumor of temporal bone with pachymeningitis, cranial neuropathies and uveitis
    A Hyun Cho
    Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Eur Neurol 51:238-40. 2004
  83. ncbi Vascular anomalies, sutures and small canals of the temporal bone on axial CT
    Sabrina Koesling
    Department of Diagnostic Radiology, University of Halle, E Grube Str 40, 06097 Halle, Germany
    Eur J Radiol 54:335-43. 2005
    Subtle bony structures, small canals and fine sutures cause sometimes problems in the analysis of CTs of the temporal bone. The aim of this study was: to analyze the visibility of subtle structures and to estimate the incidence of ..
  84. doi Management of meningoencephalic herniation of the temporal bone: Personal experience and literature review
    Mario Sanna
    Otology and Skull Base Surgery, Gruppo Otologico, Piacenza, Italy
    Laryngoscope 119:1579-85. 2009
    b>Temporal bone meningoencephalic herniation is a rare condition with potentially dangerous complications...
  85. doi Immunoglobulin G4 related systemic sclerosing disease involving the temporal bone
    L Masterson
    Department of Otolaryngology, Norfolk and Norwich University Hospital, UK
    J Laryngol Otol 124:1106-10. 2010
    To report a rare condition affecting the temporal bone. Immunoglobulin G4 related systemic sclerosing disease is a recently described autoimmune condition with manifestations typically involving the pancreas, biliary system, salivary ..
  86. doi An intraoral surgical approach to the styloid process in Eagle's syndrome
    Bruno Ramos Chrcanovic
    Oral Maxillofac Surg 13:145-51. 2009
    ..A literature review is also presented...
  87. ncbi Hearing levels in patients with microtia: correlation with temporal bone malformation
    Shin Ichi Ishimoto
    Department of Otolaryngology, Social Insurance Central General Hospital, Tokyo, Japan
    Laryngoscope 117:461-5. 2007
    To evaluate the relationship between hearing level and temporal bone abnormalities in patients with microtia.
  88. pmc Three-dimensional virtual model of the human temporal bone: a stand-alone, downloadable teaching tool
    Haobing Wang
    Eaton Peabody Laboratory of Auditory Physiology, Massachusetts Eye and Ear Infirmary, Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Otol Neurotol 27:452-7. 2006
    To develop a three-dimensional virtual model of a human temporal bone based on serial histologic sections.
  89. doi Prevalence of the pneumatized articular eminence in the temporal bone
    Muhammed Selim Yavuz
    Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ataturk University, Erzurum, Turkey
    J Craniomaxillofac Surg 37:137-9. 2009
    The pneumatized articular eminence (PAT) of the temporal bone has been identified as an asymptomatic radiolucent appearance defect in the temporal bone...
  90. ncbi Giant-cell reparative granuloma of the temporal bone: a case report and review of the literature
    Carsten Christof Boedeker
    Department of Otorhinolaryngology Head and Neck Surgery, University of Freiburg, Killianstrasse 5, 79106 Freiburg, Germany
    Ear Nose Throat J 82:926-9, 933-4, 936-7. 2003
    ..GCRG of the temporal bone is exceedingly rare...
  91. ncbi Aneurysmal bone cyst of the temporal bone associated with reversible hemifacial paralysis
    Peter R Sabatini
    Department of Otolaryngology, University of South Alabama College of Medicine, Mobile, USA
    Am J Otolaryngol 26:261-4. 2005
    Aneurysmal bone cyst (ABC) is an uncommon lesion of the temporal bone (TB), with only 20 cases reported. Facial paralysis is a rare complication (2 cases); however, no cases have been reported with preoperative reversal of paralysis...
  92. ncbi Temporal bone encephaloceles
    Matthew T Sdano
    University of Cincinnati Medical Center, Department of Otolaryngology Head and Neck Surgery, University of Cincinnati Medical Center, Cincinnati, Ohio 45267, USA
    Curr Opin Otolaryngol Head Neck Surg 13:287-9. 2005
    This paper reviews the latest literature relating to the diagnosis and treatment of temporal bone encephaloceles, defined as the herniation of meninges or brain tissue into areas of the temporal bone, for example, the petrous apex, ..
  93. doi Inverting papilloma of the temporal bone: case report and meta-analysis of risk factors
    Jasper Shen
    UCSD School of Medicine, Department of Radiology, La Jolla, California 92093 0647, USA
    Otol Neurotol 32:1124-33. 2011
    ..To review the literature on inverting papilloma of the middle ear and mastoid with a focus on familiarizing clinicians with its presentation and cause and to discuss its epidemiologic, diagnostic, and therapeutic issues...
  94. ncbi Aneurysmal bone cyst of the temporal bone
    B Chidambaram
    Childs Nerv Syst 17:411-4. 2001
    ..Their occurrence in the calvarium is rare. We report the occurrence of an aneurysmal bone cyst in the temporal bone of a young boy, which eroded the posterior part of the orbit to cause proptosis.
  95. ncbi Eagle's syndrome: a report of 4 patients treated using a modified extraoral approach
    L H Diamond
    Oral and Maxillofacial Surgery, Cambridge, Ontario, Canada
    J Oral Maxillofac Surg 59:1420-6. 2001
    ..This study evaluated a slightly modified extraoral approach to removing the symptomatic elongated styloid process. A brief description of this surgical technique and its comparison to the intraoral approach is provided...
  96. ncbi Delineation of temporal bone anatomy: feasibility of low-dose 64-row CT in regard to image quality
    Jürgen Lutz
    Department of Clinical Radiology, University of Munich, Grosshadern, Marchioninistr 15, 81377, Munich, Germany
    Eur Radiol 17:2638-45. 2007
    The aim of our present study was to evaluate the visualization of anatomical landmarks of the temporal bone using a low-dose 64-slice computed tomography (CT) technique. A total of 120 patients were evaluated, 60 patients (mean age 47...
  97. ncbi [Computed tomography and magnetic resonance tomography of the normal temporal bone]
    C Czerny
    Abteilung für Osteologie, Univ Klinik fur Radiodiagnostik, AKH Wien, Vienna, Austria
    Radiologe 43:200-6. 2003
    The normal anatomy of the temporal bone and the inner ear will be described in detail on high resolution computed tomography (HRCT) and magnetic resonance images...
  98. ncbi Computed tomography imaging of the temporal bone--normal anatomy
    A T Ahuja
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, HKSAR, China
    Clin Radiol 58:681-6. 2003
    This review describes the fundamental anatomical structures of the temporal bone as depicted on high-resolution computed tomography, and the clinical significance of these structures...
  99. ncbi Presbycusis: a human temporal bone study of individuals with flat audiometric patterns of hearing loss using a new method to quantify stria vascularis volume
    Erik G Nelson
    Section of Otolaryngology Head and Neck Surgery, University of Chicago Medical Center, 5841 S Maryland Avenue, MC 1035, Chicago, IL 60637, USA
    Laryngoscope 113:1672-86. 2003
    ..Stria vascularis volume was not measured in these studies...
  100. ncbi Inflammatory pseudotumor of the temporal bone
    Robert A Williamson
    Bobby R Alford Department of Otorhinolaryngology, Baylor College of Medicine and The Methodist Hospital, Houston, TX 77030, USA
    Otol Neurotol 24:818-22. 2003
    ..presentation, imaging characteristics, intraoperative findings, and key histopathologic features of inflammatory pseudotumors of the temporal bone. Findings from an index case are presented, and the literature is reviewed for comparison.
  101. ncbi Fluctuant, progressive hearing loss associated with Menière like vertigo in three patients with the Pendred syndrome
    C Stinckens
    Department of Otorhinolaryngology, Head and Neck Surgery, KU, Leuven, Belgium
    Int J Pediatr Otorhinolaryngol 61:207-15. 2001
    ..CONCLUSIONS: Patients with Pendred syndrome may exhibit progressive and fluctuant hearing loss with episodes of vertigo...

Research Grants69

  1. Human middle-ear imaging, physiology, and biomechanics
    CHARLES RICHARD STEELE; Fiscal Year: 2013
    ..Specific Aim #2: The human middle-ear cavity is known to be an irregularly shaped space within the temporal bone that varies from person to person...
  2. CLONING OF THE Hol MUTATION
    Licia Selleri; Fiscal Year: 2009
    ..Finally, the cartilage primordium of the petrous part of the temporal bone is absent, leaving a hollow space (therefore this line will be defined hereafter as "Hollow ear", or Hol), and ..
  3. Ossicle vibration measurements in conductive hearing loss
    Steven L Jacques; Fiscal Year: 2013
    ..In Aim 2 we use the prototype otoscope to study human temporal bone specimens to investigate ossicular chain 'disorders'by experimental ossicle fixations and ..
  4. Microscopy in the cochlea
    Mark J Schnitzer; Fiscal Year: 2011
    ..manipulation, due to its complex structure, small size, fragility, and embedded location deep within the temporal bone. This inaccessibility to microscopic inspection has long been a major hindrance to advances in clinical ..
  5. Drosophila model for noise-induced hearing loss
    Daniel F Eberl; Fiscal Year: 2012
    ..Mammalian studies are challenged by difficult access to the inner ear inside the temporal bone, and expensive animal care costs...
  6. The Otopathology of Hearing Loss: Genotype-Phenotype Correlation in Human TB
    Fred H Linthicum; Fiscal Year: 2013
    ..such connections remain largely unknown, and the only source of this information is the existing post-mortem temporal bone collections...
  7. Optopathology by Light Microscopy and Molecular Techniques
    Michael J McKenna; Fiscal Year: 2013
    ..the purview of clinical departments of pathology, and is therefore a research endeavor that is performed in temporal bone laboratories...
  8. Otopathology by Light Microscopy and Molecular Techniques
    Saumil N Merchant; Fiscal Year: 2010
    ..the purview of clinical departments of pathology, and is therefore a research endeavor that is performed in temporal bone laboratories...
  9. Modern Studies of the Human Temporal Bone
    AKIRA NONE ISHIYAMA; Fiscal Year: 2010
    Human temporal bone studies have contributed significantly to our understanding of the pathophysiology of hearing and balance disorders...
  10. OTITIS MEDIA RESEARCH CENTER
    Charles Bluestone; Fiscal Year: 1990
    ..anatomy and computer imaging of histological and histopathologic specimens of the Eustachian tube (ET) and temporal bone; biochemical and enzyme composition of middle-ear effusions; studies of OME and hearing in a Rhesus monkey ..
  11. Coupling Strategies for Middle Ear Protheses
    ANN GRONDA; Fiscal Year: 2003
    ..whose physical properties match those of middle ear structures will be selected and characterized in bench and temporal bone studies. Initial candidates include silicone medical adhesive, fibrin glue and BioGlue...
  12. Cell and Molecular Analysis of Human Temporal Bones
    Fred H Linthicum; Fiscal Year: 2010
    ..A consortium of temporal bone centers will greatly enhance the data and resource sharing and will undoubtedly promote collaborations...
  13. SENSORINEURAL HEARING LOSS--PERILYMPHATIC FISTULAS
    Robert Kohut; Fiscal Year: 1999
    ..Ready for submission). (3) The collection of human temporal bone specimens from consecutive autopsies is providing strong preliminary statistical data regarding the frequency ..
  14. Virtual Temporal Bone Surgery: Defining and Translating Standardized Metrics to a
    GREGORY JAMES WIET; Fiscal Year: 2013
    ..funding, we have developed an intuitive virtual simulation environment to be used as an adjuvant for teaching temporal bone surgery...
  15. Precision Freehand Sculpting for Skull Base
    Constantinos Nikou; Fiscal Year: 2009
    ..Specific Aim 3 - Design and implement semi-automated planning algorithms and interfaces for temporal bone surgery. Preoperative planning must be fast and easy to be acceptable for widespread clinical use...
  16. HUMAN MODEL OF VESTIBULAR DEAFFERENTATION
    Akira Ishiyama; Fiscal Year: 2001
    ..One unique aspect of the present proposal is that a wide variety of human temporal bone and brain stem specimens are available for this study, including autopsy, archival and surgical specimens...
  17. ACOUSTICAL ASPECTS OF MIDDLE EAR RECONSTRUCTIVE SURGERY
    SAUMIL MERCHANT; Fiscal Year: 2000
    ..g., sound pressure, ossicular motion, acoustic impedance) in a surgically-modified human temporal bone preparation with anatomical measurements of structure-function relationships of a reconstructed ear which can ..
  18. Development of Methods and Software for Interior Tomography Applications
    Hengyong Yu; Fiscal Year: 2009
    ..implications, and will benefit or enable a wide range of CT applications including lung CT, cardiac CT, temporal bone imaging, intraoperative CT and so on, where we need to handle large objects, minimize radiation dose, suppress ..
  19. Micro Sensor for Cochlear and Middle Ear Implant Systems
    WEN KO; Fiscal Year: 2005
    ..and (4) to evaluate the prototype sensor and the bio-electronic microphone in the laboratory and in the temporal bone expedients to assess the feasibility of pursuing the future development of totally implantable cochlear system ..
  20. SPECTROSCOPY FOR ALZHEIMER'S DISEASE DIAGNOSIS
    Michael Feld; Fiscal Year: 2001
    ..Preliminary studies performed at the LBRC comparing specimens of normal and AD temporal cortex and temporal bone, provided by VAMC (including both microscopic and bulk samples), show very promising signatures in both ..
  21. HISTOPATHOLOGY OF TEMPORAL BONES
    Isamu Sando; Fiscal Year: 2000
    ..Sando and colleagues have developed a unique technique for harvesting the temporal bone and entire ET-ME system as a single specimen...
  22. R&D-OTHER SVC &DEVELOP-B RES
    Joseph B Nadol; Fiscal Year: 2009
    ..organization primarily to provide an infrastructure service across the country for acquiring high quality temporal bone specimens and related brain tissues, and to provide an information superstructure for storing and ..
  23. SPATIAL DYNAMICS OF PROTEIN TURNOVER IN COCHLEA
    Claude Lechene; Fiscal Year: 2002
    ..in a variety of cochlear location: stereocilia, tectorial membrane, Reissner membrane spiral ganglion and temporal bone. The resolution of the mass images is easily 50 nm...
  24. VIRTUAL SIMULATION OF TEMPORAL BONE DISSECTION
    Gregory Wiet; Fiscal Year: 2001
    ..and software to create a robust, realistic virtual environment for synthesizing the techniques involved in temporal bone dissection...
  25. Transcriptome and Proteome Analysis of Mouse Inner Ears
    Qing Zheng; Fiscal Year: 2007
    ..have been attempted because of the difficulty of accessing the small numbers of diverse cells within the hard temporal bone that encases the inner ear...
  26. CONFERENCE ON MOLECULAR BIOLOGY OF HEARING AND DEAFNESS
    Allen Ryan; Fiscal Year: 2001
    ..the molecular substrates of auditory function; transgenic models in auditory function; molecular biology of temporal bone disease; molecular biology of hair cell damage, regeneration and protection; molecular medicine for the ..
  27. NIDCD NAT TEMPORAL BONE HEARING & BALANCE PATH RES
    JOSEPH NADOL; Fiscal Year: 2000
    The purpose of this contract is to maintain and further develop the NIDCD National Temporal Bone, Hearing and Balance Pathology Resource Registry that serves as a national resource for both the public and the biomedical research ..
  28. OTOPATHOLOGY BY LIGHT MICROSCOPY
    HAROLD SCHUKNECHT; Fiscal Year: 1993
    ..will dome from the several morgues of the hospitals serving Harvard Medical School, as well as from the Temporal Bone Bank Program and cooperating otolaryngologists in the USA and several foreign countries...
  29. MULTI-SLICE CT IMAGING TECHNIQUES FOR ULTRA-THIN SLICES
    Hui Hu; Fiscal Year: 2000
    ..imaging capability at only slightly reduced volume coverage speed, for challenging applications such as temporal bone imaging...
  30. Ear Biomechanics for Restoration of Hearing
    RONG GAN; Fiscal Year: 2009
    ..in the project: (a) accurate geometric reconstruction of entire human ear based on histological images of temporal bone morphometry;(b) direct, accurate measurement of viscoelastic properties of middle ear tissues using the ..
  31. MOLECULAR ANALYSES OF TEMPORAL BONE DEVELOPMENT
    E Crenshaw; Fiscal Year: 2008
    ..However, the specific roles that BMP signaling plays in the chondrogenesis of the temporal bone, and in the formation of the semicircular canals and vestibular sensory epithelia are poorly understood...
  32. Mechanism of Opiate Induced Audiovestibular Dysfunction
    Gail Ishiyama; Fiscal Year: 2006
    ....
  33. Image-Guided Otologic Surgery
    Robert Labadie; Fiscal Year: 2004
    ..It is anticipated that this system will make ear surgery safer and more efficient. ..
  34. Tongue Volume, Function and Biomechanics
    Zi Jun Liu; Fiscal Year: 2006
    ..Application of this information will allow understanding of normal tongue functional morphology and to evaluate how tongue volume affects function and craniofacial growth. ..
  35. Robotic Mastoidectomy
    Robert Labadie; Fiscal Year: 2008
    ..To that end, the motion of a drill used by surgeons to mill away bone as they perform mastoidectomies in the temporal bone laboratory will be tracked via an image-guided surgical system...
  36. DEVELOPMENT OF A MIDDLE EAR BALLOON IMPLANT
    SAUMIL MERCHANT; Fiscal Year: 2003
    ..There is a large market potential for this implant, estimated at over 65,000 devices annually in the U.S. alone. ..
  37. Vestibular Pathology in Meniere's Disease
    Akira Ishiyama; Fiscal Year: 2007
    ..or with alterations in neuronal number or size? 6) What are the morphometric correlates to abnormalities on traditional vestibular testing: caloric paresis, and decreased gain and time constant on step rotational testing? ..
  38. Herpesviruses in Vestibular Neuritis
    JEFFREY VRABEC; Fiscal Year: 2003
    ..This information can help determine why some individuals with latent virus in the vestibular ganglion develop clinical symptoms due to reactivation and some do not. ..
  39. Intranigral Transplantation in Parkinsonian Monkeys
    Thyagarajan Subramanian; Fiscal Year: 2010
    ..Proposed studies will better delineate the pathophysiology of PD and drug induced dyskinesias and potentially bring us close to the ideal of complete restoration of the nigrostriatal dopaminergic pathway in PD. ..
  40. Genetic Modulation of Noise Injury to the Cochlear Lateral Wall
    KEVIN OHLEMILLER; Fiscal Year: 2009
    ..The gene, and the processes in which it is involved, may affect the long-term stability of cochlear injury, and the accumulation of injury that may be diagnosed as presbycusis. ..
  41. Validation/Dissemination Virtual Temporal Bone Dissection
    Gregory Wiet; Fiscal Year: 2008
    ..For this specific project, our focused hypothesis is that a virtual environment for temporal bone dissection is equivalent to training with cadaveric temporal bone dissection in the anatomy laboratory...
  42. Genetics and Pediatric Nonsyndromic Hearing Loss
    Margaret Kenna; Fiscal Year: 2005
    ..3.) The diagnostic evaluation of the hearing loss will include temporal bone imaging studies, as the presence of anatomic temporal bone abnormalities is frequently associated with ..
  43. ASNTR Annual Meeting Student Travel Awards
    Thyagarajan Subramanian; Fiscal Year: 2007
    ..ASNTR and its educational committee includes and encourages participation of minorities including women and persons with disabilities in all its activities. [unreadable] [unreadable] [unreadable]..
  44. Mucana Pruriens for dyskinesias in Parkinson's disease
    Thyagarajan Subramanian; Fiscal Year: 2006
    ..abstract_text> ..
  45. Molecular biology of deafness in the Meniere's Model
    CLIFF MEGERIAN; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  46. SYMPOSIA FOR ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
    Elizabeth Keithley; Fiscal Year: 2008
    ..abstract_text> ..
  47. Electromechanics of the Cochlear Outer Hair Cell
    William E Brownell; Fiscal Year: 2011
    ..The final result will be a complete description of OHC electromechanical force production and its role in hearing. ..
  48. BONE GROWTH, PERIOSTEAL MIGRATION AND MUSCLE FUNCTION
    Susan Herring; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  49. Identify genes causing Kabuki Syndrome
    JEFFREY MILUNSKY; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  50. MECHANICAL ENVIRONMENT IN MANDIBULAR DISTRACTION
    Susan Herring; Fiscal Year: 2006
    ....
  51. Diseases of the Vestibular System
    Robert Baloh; Fiscal Year: 2006
    ..abstract_text> ..
  52. Identify Waardenburg syndrome type 2 loci in man
    JEFFREY MILUNSKY; Fiscal Year: 2005
    ..We will perform a high-density genome scan coupled with linkage disequilibrium analyses on 3 large multigenerational families and multiple smaller families with WS2 to identify candidate gene(s) with mutations causing WS2. ..
  53. DIZZINESS IN OLDER PEOPLE
    Robert Baloh; Fiscal Year: 2006
    ..Prior histopathological studies in older people with balance dysfunction have focused on the temporal bone or brain but not both, have lacked detailed clinical data, and rarely have contained quantitative information ..
  54. Genetic Modulation of Noise Injury to the Cochlear Lateral Wall
    KEVIN OHLEMILLER; Fiscal Year: 2007
    ..The gene, and the processes in which it is involved, may affect the long-term stability of cochlear injury, and the accumulation of injury that may be diagnosed as presbycusis. ..
  55. INNER EAR IMMUNE RESPONSES
    Elizabeth Keithley; Fiscal Year: 2002
    ..inner ear immune response involves the endolymphatic sac, an extension of the membraneous labyrinth within the temporal bone projecting into the dura adjacent to the sigmoid sinus of the posterior cranial fossa...
  56. Non-Invasive Localization of Vulnerable Plaques
    Cynthia McCollough; Fiscal Year: 2009
    ....
  57. Differential Gene Expression in the Cochlear Nucleus
    David Friedland; Fiscal Year: 2008
    ..These data will also provide a powerful template upon which to test and design novel treatments for improving hearing, discrimination and tinnitus in a significant portion of the population. ..
  58. MEASUREMENT OF VESTIBULAR FUNCTION IN MENIERE'S DISEASE
    Steven Rauch; Fiscal Year: 2002
    ..groundwork for detailed clinicopathological studies of the correlation between vestibular function tests and temporal bone vestibular otopathology by soliciting enrollment of study subjects as future temporal bone donors to the NIDCD ..
  59. COCHLEAR VULNERABILITY/REACTIVE OXYGEN SPECIES
    KEVIN OHLEMILLER; Fiscal Year: 2003
    ..Our experiments will establish how well the dynamics of ROS production predict cochlear injury, and whether progressive deafness genes may impair cochlear ROS regulation. ..
  60. Sudden Hearing Loss Multicenter Treatment Trial
    Steven Rauch; Fiscal Year: 2008
    ..Thus the results of this study will have significant impact on evidence-based clinical practice guidelines for management of SSNHL. This application is for the collaborating Clinical Coordinating Center (CCC). ..
  61. Development of a laser holography otoscope for diagnosis in the clinic
    John J Rosowski; Fiscal Year: 2010
    ..abstract_text> ..