radius

Summary

Top Publications

  1. ncbi Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study
    Roger M D Zebaze
    Department of Medicine, Austin Health, University of Melbourne, Melbourne, Vic, Australia
    Lancet 375:1729-36. 2010
  2. pmc Age- and gender-related differences in the geometric properties and biomechanical significance of intracortical porosity in the distal radius and tibia
    Andrew J Burghardt
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
    J Bone Miner Res 25:983-93. 2010
  3. pmc Quantitative characterization of subject motion in HR-pQCT images of the distal radius and tibia
    Miki Sode
    Joint Graduate Group in Bioengineering, University of California at San Francisco and Berkeley, San Francisco and Berkeley, CA, USA
    Bone 48:1291-7. 2011
  4. ncbi Poor trabecular microarchitecture at the distal radius in older men with increased concentration of high-sensitivity C-reactive protein--the STRAMBO study
    T Rolland
    INSERM UMR 1033, Université de Lyon and Hospices Civils de Lyon, Lyon, France
    Calcif Tissue Int 90:496-506. 2012
  5. ncbi [An alternative fixation method for the treatment of unstable distal clavicle fractures: locked distal radius plate]
    Bulent Daglar
    Department of Orthopedics and Traumatology, Ankara Numune Training and Research Hospital, Ankara, Turkey
    Acta Orthop Traumatol Turc 43:324-30. 2009
  6. pmc Reproducibility of direct quantitative measures of cortical bone microarchitecture of the distal radius and tibia by HR-pQCT
    Andrew J Burghardt
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94158, USA
    Bone 47:519-28. 2010
  7. ncbi Significant change in the surgical treatment of distal radius fractures: a nationwide study between 1998 and 2008 in Finland
    Ville M Mattila
    Division of Orthopaedics and Traumatology, Department of Trauma, Musculoskeletal Surgery and Rehabilitation, Tampere University Hospital, and Medical School, University of Tampere, Tampere, Finland
    J Trauma 71:939-42; discussion 942-3. 2011
  8. ncbi Bone geometry and density in the skeleton of pre-pubertal gymnasts and school children
    K A Ward
    Clinical Radiology, Imaging Science and Biomedical Engineering, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Bone 36:1012-8. 2005
  9. ncbi Bone micro-architecture and determinants of strength in the radius and tibia: age-related changes in a population-based study of normal adults measured with high-resolution pQCT
    N Dalzell
    Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Wort s Causeway, Cambridge, CB1 8RN, UK
    Osteoporos Int 20:1683-94. 2009
  10. ncbi Postmenopausal women with osteopenia have higher cortical porosity and thinner cortices at the distal radius and tibia than women with normal aBMD: an in vivo HR-pQCT study
    Kyle K Nishiyama
    Department of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, Canada
    J Bone Miner Res 25:882-90. 2010

Detail Information

Publications287 found, 100 shown here

  1. ncbi Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study
    Roger M D Zebaze
    Department of Medicine, Austin Health, University of Melbourne, Melbourne, Vic, Australia
    Lancet 375:1729-36. 2010
    ..We aimed to re-examine cortical bone as a source of bone loss in the appendicular skeleton...
  2. pmc Age- and gender-related differences in the geometric properties and biomechanical significance of intracortical porosity in the distal radius and tibia
    Andrew J Burghardt
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
    J Bone Miner Res 25:983-93. 2010
    ..methods applied to high-resolution peripheral quantitative computed tomography (HR-pQCT) images of the distal radius and tibia...
  3. pmc Quantitative characterization of subject motion in HR-pQCT images of the distal radius and tibia
    Miki Sode
    Joint Graduate Group in Bioengineering, University of California at San Francisco and Berkeley, San Francisco and Berkeley, CA, USA
    Bone 48:1291-7. 2011
    ..A total of 88 HR-pQCT exams with repeated acquisitions of the distal radius (N = 54) or distal tibia (N = 34) of 49 women (age = 59 ± 14 year) and 3 men (46 ± 2 year) were retrospectively ..
  4. ncbi Poor trabecular microarchitecture at the distal radius in older men with increased concentration of high-sensitivity C-reactive protein--the STRAMBO study
    T Rolland
    INSERM UMR 1033, Université de Lyon and Hospices Civils de Lyon, Lyon, France
    Calcif Tissue Int 90:496-506. 2012
    ..We assessed the association of hsCRP with bone microarchitecture (measured by high-resolution pQCT) at the distal radius and tibia in 1,149 men, aged 19-87 years...
  5. ncbi [An alternative fixation method for the treatment of unstable distal clavicle fractures: locked distal radius plate]
    Bulent Daglar
    Department of Orthopedics and Traumatology, Ankara Numune Training and Research Hospital, Ankara, Turkey
    Acta Orthop Traumatol Turc 43:324-30. 2009
    ..We evaluated the results of surgical treatment of displaced distal clavicle fractures using locked distal radius plates.
  6. pmc Reproducibility of direct quantitative measures of cortical bone microarchitecture of the distal radius and tibia by HR-pQCT
    Andrew J Burghardt
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94158, USA
    Bone 47:519-28. 2010
    ..segment and directly quantify cortical density, geometry, and microarchitecture from HR-pQCT images of the distal radius and tibia...
  7. ncbi Significant change in the surgical treatment of distal radius fractures: a nationwide study between 1998 and 2008 in Finland
    Ville M Mattila
    Division of Orthopaedics and Traumatology, Department of Trauma, Musculoskeletal Surgery and Rehabilitation, Tampere University Hospital, and Medical School, University of Tampere, Tampere, Finland
    J Trauma 71:939-42; discussion 942-3. 2011
    Studies from the United States report a large increase in the surgical treatment of distal radius fractures with open reduction and internal fixation using locked plates...
  8. ncbi Bone geometry and density in the skeleton of pre-pubertal gymnasts and school children
    K A Ward
    Clinical Radiology, Imaging Science and Biomedical Engineering, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Bone 36:1012-8. 2005
    ..We hypothesised that compared to controls, gymnasts would have larger and stronger radius and tibia diaphyses with greater bone mineral content and larger cross-sectional muscle area...
  9. ncbi Bone micro-architecture and determinants of strength in the radius and tibia: age-related changes in a population-based study of normal adults measured with high-resolution pQCT
    N Dalzell
    Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Wort s Causeway, Cambridge, CB1 8RN, UK
    Osteoporos Int 20:1683-94. 2009
    ..Important effects of ageing and contrasts in the effects of sex on the micro-architecture and strength of upper and lower limb bones were revealed...
  10. ncbi Postmenopausal women with osteopenia have higher cortical porosity and thinner cortices at the distal radius and tibia than women with normal aBMD: an in vivo HR-pQCT study
    Kyle K Nishiyama
    Department of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, Canada
    J Bone Miner Res 25:882-90. 2010
    ..The analysis was applied to distal radius and tibia HR-pQCT scans from a subset of participants from the Calgary, Alberta, cohort of the Canadian ..
  11. ncbi Volar plate fixation of distal radius fractures
    Jorge Orbay
    Miami Hand Center, 8905 Southwest 87 Avenue, Suite 100, Miami, FL 33176, USA
    Hand Clin 21:347-54. 2005
    ..be considered as the beginning of a new era in restoring wrist function to patients with dorsally displaced distal radius fractures even in the face of comminuted or osteopenic bone...
  12. pmc Treatment of reducible unstable fractures of the distal radius in adults: a randomised controlled trial of De Palma percutaneous pinning versus bridging external fixation
    João C Belloti
    Departamento de Ortopedia e Traumatologia, Universidade Federal de Sao Paulo Escola Paulista de Medicina, São Paulo 04038 032, Brazil
    BMC Musculoskelet Disord 11:137. 2010
    ..there is no conclusive evidence regarding the best treatment method for reducible unstable fractures of the distal radius. This study compared the effectiveness of two methods used in surgical treatment of such fractures: percutaneous ..
  13. pmc Internal versus external fixation for unstable distal radius fractures: an up-to-date meta-analysis
    Zhuang Cui
    Southern Medical University, Guangzhou, China
    Int Orthop 35:1333-41. 2011
    Our aim was to compare the effect of internal vs external fixation for unstable distal radius fractures regarding postoperative complications, clinical results and radiological outcomes.
  14. pmc Habitual use of the primate forelimb is reflected in the material properties of subchondral bone in the distal radius
    Kristian J Carlson
    Department of Anatomical Sciences, School of Medicine, Stony Brook University, USA
    J Anat 208:659-70. 2006
    ..We evaluated subchondral bone in the distal radius of several primates whose locomotion could be characterized in one of three general ways (quadrupedal, suspensory ..
  15. ncbi Peripheral quantitative computed tomography of the proximal radius in young subjects--new reference data and interpretation of results
    F Rauch
    Genetics Unit, Shriners Hospital for Children, Montreal, Canada
    J Musculoskelet Neuronal Interact 8:217-26. 2008
    ..provide reference data for peripheral quantitative computed tomography (Stratec XCT2000) performed at the proximal radius (the so-called '65% site') of young subjects and to discuss the interpretation of such analyses...
  16. pmc Epithelioid hemangioendothelioma of the forearm with radius involvement. Case report
    Claudia D Gherman
    Surgical Clinic No 2, Iuliu Hatieganu University of Medicine and Pharmacy, No 4 6 Clinicilor Street, 400006 Cluj Napoca, Romania
    Diagn Pathol 6:120. 2011
    ..We present the case of a young man, 24-year-old, with EHE of the forearm with secondary involvement of the distal radius. The location and the extension of the tumor allowed a wide excision, without the reconstruction of radius, ..
  17. ncbi Determinants of the first decade of bone loss after menopause at spine, hip and radius
    J Reeve
    University of Cambridge Department of Medicine, Northwick Park Hospital, UK
    QJM 92:261-73. 1999
    ..Forty-three women underwent repeated measurements of bone density at the lumbar spine, proximal femur and distal radius for up to 14 years...
  18. ncbi Relation between image-based assessment of distal radius trabecular structure and compressive strength
    C L Gordon
    Osteoporosis and Arthritis Research Group, University of California, San Francisco 94143, USA
    Can Assoc Radiol J 49:390-7. 1998
    ..To investigate the degree to which an image-based assessment of trabecular bone structure can predict bone strength...
  19. pmc Bone mass and strength in older men with type 2 diabetes: the Osteoporotic Fractures in Men Study
    Moira A Petit
    School of Kinesiology, Laboratory for Musculoskeletal Health, University of Minnesota, Minneapolis, MN, USA
    J Bone Miner Res 25:285-91. 2010
    ..At both the distal tibia and radius, patients with T2DM had greater bone vBMD (+2% to +4%, model 1, p < ...
  20. ncbi Ulnar growth patterns in radial longitudinal deficiency
    Anthony M Sestero
    Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN 55454, USA
    J Hand Surg Am 31:960-7. 2006
    ..To determine the association between centralization surgical procedures and the longitudinal growth of the ulna in radial longitudinal deficiency (RLD)...
  21. pmc Which treatment is the best for giant cell tumors of the distal radius? A meta-analysis
    Yu Peng Liu
    Department of Orthopaedics, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410008, PR China
    Clin Orthop Relat Res 470:2886-94. 2012
    Intralesional excision and en bloc resection are used to treat giant cell tumors (GCTs) of the distal radius. However, it is unclear whether one provides lower rates of recurrences and fewer complications, and whether the use of ..
  22. ncbi Radius pull test: predictor of longitudinal forearm instability
    Adam M Smith
    Department of Orthopedic Surgery, Wake Forest University Baptist Medical Center, Medical Center Boulevard, Box 1070, Winston Salem, NC 27157, USA
    J Bone Joint Surg Am 84:1970-6. 2002
    ..This cadaveric study examines a stress test that can be performed in the operating room to identify injury to the ligamentous structures of the forearm...
  23. ncbi The effect of fracture-related factors on the functional outcome at 1 year in distal radius fractures
    Sumit Batra
    Department of Orthopaedics, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, India
    Injury 33:499-502. 2002
    Sixty-nine cases of distal radius fracture were studied retrospectively for various factors that might affect the functional outcome...
  24. ncbi Pre-centralization soft tissue distraction for Bayne type IV congenital radial deficiency in children
    Sanjeev Sabharwal
    Department of Orthopedics, UMDNJ New Jersey Medical School, Doctors Office Center, 90 Bergen Street, Newark, NJ 07103, USA
    J Pediatr Orthop 25:377-81. 2005
    ..All families were pleased with the results. These findings suggest that a staged surgical approach is a technically feasible alternative in the treatment of severe congenital radial club hand deformity in young children...
  25. ncbi Finite element analysis performed on radius and tibia HR-pQCT images and fragility fractures at all sites in postmenopausal women
    Nicolas Vilayphiou
    INSERM Research Unit 831 and Université de Lyon, Lyon, France
    Bone 46:1030-7. 2010
    Assessment of bone strength at the radius by micro-finite element analysis (muFEA) has already been associated with wrist fractures...
  26. ncbi HR-pQCT based FE analysis of the most distal radius section provides an improved prediction of Colles' fracture load in vitro
    Peter Varga
    Institute of Lightweight Design and Structural Biomechanics, Vienna University of Technology, Gußhausstraße 27 29, A 1040 Vienna, Austria
    Bone 47:982-8. 2010
    ..The remarkable performances of high-resolution peripheral quantitative computed tomography (HR-pQCT) make the distal radius a favorable site for early diagnosis of osteoporosis and improved Colles' fracture risk assessment...
  27. ncbi The recurrence of deformity after surgical centralization for radial clubhand
    E Damore
    Department of Orthopaedic Surgery, Temple University, Philadelphia, PA, USA
    J Hand Surg Am 25:745-51. 2000
    ....
  28. pmc Abnormal microarchitecture and reduced stiffness at the radius and tibia in postmenopausal women with fractures
    Emily M Stein
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Bone Miner Res 25:2572-81. 2010
    ..fracture had aBMD measured by DXA and trabecular and cortical vBMD and trabecular microarchitecture of the radius and tibia measured by HR-pQCT...
  29. ncbi Distraction and microvascular epiphysis transfer for radial club hand
    S K Vilkki
    Department of Hand and Microsurgery, Tampere University Hospital, Finland
    J Hand Surg Br 23:445-52. 1998
    ..This technique appears to be promising but is demanding because of the microvascular joint transplantation at an early age...
  30. ncbi Buttressing angle of the double-plating fixation of a distal radius fracture: a finite element study
    Chun Li Lin
    Department of Mechanical Engineering, Chang Gung University, 259 Wen Hua 1st Road, Kwei Shan, Tao Yuan, 333, Taiwan
    Med Biol Eng Comput 44:665-73. 2006
    Treatment of a distal radius fracture should consider principles including stable fixation and early motion...
  31. ncbi Finite element analysis performed on radius and tibia HR-pQCT images and fragility fractures at all sites in men
    Nicolas Vilayphiou
    INSERM Research Unit 831 and Université de Lyon, Lyon, France
    J Bone Miner Res 26:965-73. 2011
    ..assessed by high resolution (HR)-pQCT, and finite element (µFE) analysis was based on HR-pQCT images of distal radius and tibia...
  32. ncbi Serum leptin and adiponectin are positively associated with bone mineral density at the distal radius in patients with type 2 diabetes mellitus
    Tomoko Tamura
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Metabolism 56:623-8. 2007
    ..Bone mineral density was measured by using dual-energy x-ray absorptiometry at different sites (distal radius, femoral neck, and lumbar spine) and was expressed as z score...
  33. ncbi Functional outcome after centralization for radius dysplasia
    Charles A Goldfarb
    Department of Orthopaedic Surgery, Barnes Jewish Hospital at Washington University, One Barnes Hospital Plaza, St Louis, MO 63110, USA
    J Hand Surg Am 27:118-24. 2002
    Centralization for radius dysplasia purportedly offers a more normal appearance, provides length to a shortened forearm, and improves upper-extremity function. Limited objective outcome data, however, exist to substantiate its use...
  34. pmc The association of disproportionate skeletal growth and abnormal radius dimension ratio with curve severity in adolescent idiopathic scoliosis
    Wei Jun Wang
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, 5 F, Clinical Science Building, Shatin, NT, Hong Kong SAR, China
    Eur Spine J 19:726-31. 2010
    ..whether disproportional ossification and skeletal growth occurred in the peripheral bone of AIS patients using the radius as the target bone...
  35. ncbi Decreased bone mineral density at the distal radius, but not at the lumbar spine or the femoral neck, in Japanese type 2 diabetic patients
    T Majima
    Department of Endocrinology and Metabolism, Rakuwakai Otowa Hospital, Kyoto, Japan
    Osteoporos Int 16:907-13. 2005
    ..density (BMD) at the sites with different cortical/cancellous bone ratio (lumbar spine, femoral neck, and distal radius) using dual-energy X-ray absorptiometry...
  36. ncbi Giant cell tumour of the distal radius: wide resection and reconstruction by non-vascularised proximal fibular autograft
    Ayman Abdelaziz Bassiony
    Orthopaedic Surgery, Ain Shams University, Egypt
    Ann Acad Med Singapore 38:900-4. 2009
    ..Juxtaarticular giant cell tumours of the lower end radius are common and present a special problem of reconstruction after tumour excision...
  37. pmc Muscle weakness, spasticity and disuse contribute to demineralization and geometric changes in the radius following chronic stroke
    M Y C Pang
    Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hung Hom, Hong Kong, China
    Osteoporos Int 18:1243-52. 2007
    Bone health status of the radius in individuals with chronic stroke was evaluated using peripheral quantitative computed tomography...
  38. ncbi Bone strength at the distal radius can be estimated from high-resolution peripheral quantitative computed tomography and the finite element method
    Joshua A MacNeil
    Department of Mechanical and Manufacturing Engineering, Schulich School of Engineering, University of Calgary, Calgary, Canada
    Bone 42:1203-13. 2008
    ..tomography, the finite element (FE) analysis may provide a means to assess patient bone strength in the distal radius. The purpose of this study was to determine an appropriate FE procedure to estimate bone strength by comparison ..
  39. ncbi Denosumab improves density and strength parameters as measured by QCT of the radius in postmenopausal women with low bone mineral density
    H K Genant
    Dept of Radiology, University of California, San Francisco, CA 94143, USA
    Bone 47:131-9. 2010
    ..tomography (QCT) separately assesses cortical and trabecular bone reliably at various sites, including the distal radius where there is a gradation of cortical and trabecular bone...
  40. ncbi The impact of accurate positioning on measurements made by peripheral QCT in the distal radius
    E J Marjanovic
    Clinical Radiology, Imaging Science and Biomedical Engineering, The University of Manchester, Manchester, UK
    Osteoporos Int 20:1207-14. 2009
    ..The results showed 25% of scans were not performed in the same anatomical location at follow-up when one section was scanned. These results have implications for accurate follow-up BMD measurements...
  41. ncbi Long-term protein intake and dietary potential renal acid load are associated with bone modeling and remodeling at the proximal radius in healthy children
    Ute Alexy
    Research Institute of Child Nutrition, Dortmund, Germany
    Am J Clin Nutr 82:1107-14. 2005
    ..Protein and alkalizing minerals are increasingly described as playing a major role in influencing bone status, not only in the elderly but also in children and adolescents...
  42. pmc Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD
    Lishu Zhang
    Institute of Bioscience and Biotechnology, School of Science, Beijing Jiaotong University, Beijing, People s Republic of China
    J Bone Miner Res 25:1572-80. 2010
    ..important to wrist BMD variation, we used a novel pathway-based analysis approach in our GWAS of wrist ultradistal radius (UD) BMD, examining approximately 500,000 SNPs genome-wide from 984 unrelated whites...
  43. ncbi Effects on bone geometry, density, and microarchitecture in the distal radius but not the tibia in women with primary hyperparathyroidism: A case-control study using HR-pQCT
    Stinus Hansen
    Department of Endocrinology, Odense University Hospital, Odense, Denmark
    J Bone Miner Res 25:1941-7. 2010
    ..HR-pQCT) is a new technique for in vivo assessment of geometry, volumetric density, and microarchitecture at the radius and tibia. In this study we aimed to evaluate bone status in women with PHPT compared with controls using HR-pQCT...
  44. ncbi The in vivo bone formation by mesenchymal stem cells in zein scaffolds
    Jinwen Tu
    The Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 225 South Chongqing Road, Shanghai 200025, PR China
    Biomaterials 30:4369-76. 2009
    ..Furthermore, we implanted them into the radius defects of rabbits and assessed whether they could be helpful in the repair of critical-sized bone defects...
  45. ncbi Role of sex steroids in the regulation of bone morphology in men. The MINOS study
    P Szulc
    INSERM Research Unit 403, Hopital Edouard Herriot, Place d Arsonval, 69437, Lyon, France
    Osteoporos Int 15:909-17. 2004
    ..cross-sectional area (CSA), section modulus, buckling ratio and strength index of the femoral neck and distal radius on 760 men aged 40-85 years...
  46. ncbi A physical model for dual-energy X-ray absorptiometry--derived bone mineral density
    H Sievanen
    Bone Research Group, UKK Institute, Tampere, Finland
    Invest Radiol 35:325-30. 2000
    ..The goal of this study was to develop and validate a physical model for appropriate interpretation of BMD...
  47. ncbi Non-invasive bone competence analysis by high-resolution pQCT: an in vitro reproducibility study on structural and mechanical properties at the human radius
    Thomas L Mueller
    Institute for Biomechanics, ETH Zurich, Zurich, Switzerland
    Bone 44:364-71. 2009
    ....
  48. ncbi Functional outcome of en bloc excision and osteoarticular allograft replacement with the Sauve-Kapandji procedure for Campanacci grade 3 giant-cell tumor of the distal radius
    Robert M Szabo
    Department of Orthopaedic Surgery, School of Medicine, University of California, Davis, Sacramento, 95817, USA
    J Hand Surg Am 31:1340-8. 2006
    Multiple options have been reported for reconstruction of Campanacci grade 3 giant-cell tumor of the distal radius after resection...
  49. ncbi Association of physical activity with trabecular microstructure and cortical bone at distal tibia and radius in young adult men
    M Nilsson
    Center for Bone Research at the Sahlgrenska Academy, Institute of Medicine, University of Gothenburg, 416 45 Gothenburg, Sweden
    J Clin Endocrinol Metab 95:2917-26. 2010
    ..The relationship between physical activity, trabecular microstructure, and cortical geometry in weight-bearing and non-weight-bearing bone has not previously been studied in men...
  50. pmc Variations in morphological and biomechanical indices at the distal radius in subjects with identical BMD
    Galateia J Kazakia
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, 185 Berry Street, San Francisco, CA, USA
    J Biomech 44:257-66. 2011
    ..The goal of this study was to determine--within groups of subjects with identical radius aBMD values--the extant variation in densitometric, geometric, microstructural, and biomechanical parameters...
  51. ncbi Do radiographic indices of distal radius fracture reduction predict outcomes in older adults receiving conservative treatment?
    J L Jaremko
    Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada
    Clin Radiol 62:65-72. 2007
    ..To investigate whether radiographic deformities suggesting inadequate reduction would be associated with adverse clinical outcomes...
  52. ncbi A ceramic prosthesis for the treatment of tumours of the distal radius
    H Hatano
    Department of Orthopaedic Surgery, Niigata Cancer Center Hospital, Niigata, Japan
    J Bone Joint Surg Br 88:1656-8. 2006
    ..following juxta-articular resection of tumours, there are few reports of prosthetic replacement of the distal radius. We present two cases of massive bone defects of the distal radius in which alumina ceramic prosthetic ..
  53. ncbi Early impairment of trabecular microarchitecture assessed with HR-pQCT in patients with stage II-IV chronic kidney disease
    Justine Bacchetta
    Centre de Référence des Maladies Rénales Rares, Service de Néphrologie et Rhumatologie Pédiatriques, Hopital Femme Mere Enfant, Bron, France
    J Bone Miner Res 25:849-57. 2010
    ..3D imaging technique [high-resolution peripheral quantitative computed tomography (HR-pQCT)] at the tibia and radius in 70 stage II-IV CKD patients older than 50 years of age; controls belonged to two cohorts of healthy subjects ..
  54. ncbi Outcome following nonoperative treatment of displaced distal radius fractures in low-demand patients older than 60 years
    B T Young
    Department of Orthopaedic Surgery, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
    J Hand Surg Am 25:19-28. 2000
    ..evaluated for function and radiographic results following nonoperative treatment of displaced distal radius fractures. The mean age was 72 years and the average follow-up period was 34 months...
  55. ncbi Paraarticular trabecular bone loss at the ultradistal radius and increased arterial stiffening in postmenopausal patients with rheumatoid arthritis
    Kazumasa Tanaka
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, and Senboku Second Hospital, Asahi machi, Osaka, Japan
    J Rheumatol 33:652-8. 2006
    ..Our aim was to examine whether arterial stiffening, another aspect of atherosclerosis, is also increased in patients with RA, and to determine if it is an important risk factor...
  56. ncbi Reproducibility of trabecular bone structure measurements of the distal radius at 1.5 and 3.0 T magnetic resonance imaging
    Thomas Baum
    Institut fur Radiologie, Klinikum rechts der Isar, Technische Universitat Munchen, Munchen, Germany
    J Comput Assist Tomogr 36:623-6. 2012
    ..this study was to assess and compare the reproducibility of trabecular bone structure measurements of the distal radius at 1.5 and 3.0 T magnetic resonance imaging (MRI). Root mean square reproducibility errors ranged from 0.69% to 4...
  57. ncbi Peripheral quantitative computed tomography of the distal radius in young subjects - new reference data and interpretation of results
    F Rauch
    Genetics Unit, Shriners Hospital for Children, Montreal, Canada
    J Musculoskelet Neuronal Interact 5:119-26. 2005
    ..interpretation of results for peripheral quantitative computed tomography (Stratec XCT2000 performed at the distal radius of young subjects...
  58. pmc Performance of the MRI-based virtual bone biopsy in the distal radius: serial reproducibility and reliability of structural and mechanical parameters in women representative of osteoporosis study populations
    Shing Chun Benny Lam
    Laboratory for Structural NMR Imaging, Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Bone 49:895-903. 2011
    ..performance of the MRI-based virtual bone biopsy in terms of 26 structural and mechanical parameters in the distal radius of 20 women in the age range of 50 to 75 years (mean=62.0 years, S.D.=8...
  59. ncbi The hominoid proximal radius: re-interpreting locomotor behaviors in early hominins
    Biren A Patel
    Interdepartmental Doctoral Program in Anthropological Sciences, Stony Brook University, Stony Brook, NY 11794 4364, USA
    J Hum Evol 48:415-32. 2005
    ..Specifically, morphometric variables of the proximal radius were derived from measurements from a sample of all genera of extant hominoids and casts of extinct hominin ..
  60. ncbi Long-term results of surgery for forearm deformities in patients with multiple cartilaginous exostoses
    Shosuke Akita
    Department of Orthopaedic Surgery, National Hospital Organization Osaka Minami Medical Center, 2 1 Kidohigashi, Kawachinagano, Osaka 586 8521, Japan
    J Bone Joint Surg Am 89:1993-9. 2007
    ..The purpose of the present study was to determine the reasonable indications for operative treatment and to evaluate long-term results of forearm surgery in these patients...
  61. ncbi Variable-angle locking screw volar plating of distal radius fractures
    Jung H Park
    Department of Orthopaedic Surgery, Temple University Hospital, 3401 North Broad Street, Philadelphia, PA 19140, USA
    Hand Clin 26:373-80, vi. 2010
    Surgical treatment options for distal radius fractures are many and commonly involve volar locked plating...
  62. ncbi Local topological analysis at the distal radius by HR-pQCT: Application to in vivo bone microarchitecture and fracture assessment in the OFELY study
    J B Pialat
    Inserm U1033, France
    Bone 51:362-8. 2012
    ..peripheral quantitative computed tomography (HR-pQCT) is an in-vivo technique used to analyze the distal radius and tibia. It provides a voxel size of 82μm...
  63. ncbi Radiological evaluation of the effect of biphasic calcium phosphate scaffold (HA+TCP) with 5, 10 and 20 percentage of porosity on healing of segmental bone defect in rabbit radius
    M R Farahpour
    Department of Clinical Science, Islamic Azad University, Uromia, Iran
    Bratisl Lek Listy 113:529-33. 2012
    ..induction of general anesthesia, a segmental bone defect of 10 mm in length was created in the middle of the right radius shaft. In group A, the defect was stabilized with miniplate and 2 screws and left untreated...
  64. pmc The use of beta-tricalcium phosphate bone graft substitute in dorsally plated, comminuted distal radius fractures
    Michael G Jakubietz
    Department of Trauma, Hand, Plastic and Reconstructive Surgery, University of Wuerzburg, Wuerzburg, Germany
    J Orthop Surg Res 6:24. 2011
    Intraarticular distal radius fractures can be treated with many methods...
  65. ncbi Gender differences in trabecular bone architecture of the distal radius assessed with magnetic resonance imaging and implications for mechanical competence
    Martin Hudelmaier
    Institute of Anatomy and Muskuloskeletal Research, Paracelsus Medical Private University, Strubergasse 21, 5020 Salzburg, Austria
    Osteoporos Int 16:1124-33. 2005
    ..Despite obvious gender differences in fracture incidence at the distal radius, little is known about gender differences in trabecular bone microarchitecture and its relationship to the ..
  66. ncbi Treatment of distal clavicle fracture with distal radius volar locking compression plate
    Chao Yu
    Department of Orthopedics, Shanghai Key Laboratory of Orthopaedic Implant, Ninth People s Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200011, China
    Chin J Traumatol 12:299-301. 2009
    To observe the early clinical outcomes of the internal fixation with distal radius volar locking compression plate (LCP) in treatment of distal clavicle fracture.
  67. ncbi Impact of denosumab on the peripheral skeleton of postmenopausal women with osteoporosis: bone density, mass, and strength of the radius, and wrist fracture
    James A Simon
    George Washington University, Washington DC, USA
    Menopause 20:130-7. 2013
    The aim of this study was to report the effects of denosumab on radius cortical and trabecular bone density, mass, and strength, and wrist fracture incidence in the FREEDOM (Fracture REduction Evaluation of Denosumab in Osteoporosis every ..
  68. ncbi Ontogenetic patterns of limb loading, in vivo bone strains and growth in the goat radius
    Russell P Main
    Concord Field Station, Department of Organismic and Evolutionary Biology, Harvard University, 100 Old Causeway Road, Bedford, MA 01730, USA
    J Exp Biol 207:2577-88. 2004
    ..The goal of this study was to relate forelimb loads to in vivo bone strains in the radius of the domestic goat (Capra hircus) across a range of gaits and speeds through ontogeny while observing how the ..
  69. ncbi Low-frequency axial ultrasound velocity correlates with bone mineral density and cortical thickness in the radius and tibia in pre- and postmenopausal women
    V Kilappa
    Department of Physics, University of Jyvaskyla, PO BOX 35 YFL, 40014 Jyvaskyla, Finland
    Osteoporos Int 22:1103-13. 2011
    Axial transmission velocity of a low-frequency first arriving signal (V (LF)) was assessed in the radius and tibia of 254 females, and compared to site-matched pQCT measurements...
  70. ncbi Multiscale computational and experimental approaches to elucidate bone and ligament mechanobiology using the ulna-radius-interosseous membrane construct as a model system
    M L Knothe Tate
    Departments of Biomedical Engineering and Mechanical and Aerospace Engineering, Case Western Reserve University, Cleveland, OH, USA
    Technol Health Care 20:363-78. 2012
    ..well for the study of functional adaptation in bone and the interosseous membrane, a ligament spanning between the radius and ulna...
  71. ncbi Morphology of the distal radius in extant hominoids and fossil hominins: implications for the evolution of bipedalism
    Melissa Tallman
    Department of Anthropology, City University of New York and NYCEP, New York, New York, USA
    Anat Rec (Hoboken) 295:454-64. 2012
    ..Using three-dimensional geometric morphometrics, this study tests whether the distal radius of extant hominoids is sufficient for determining locomotor pattern and the affiliations of Plio-Pleistocene ..
  72. ncbi Treatment of multiple hereditary osteochondromas of the forearm in children: a study of surgical procedures
    E K Shin
    Department of Orthopaedic Surgery UCLA, Centre for Health Sciences, 10833 LeConte Avenue, Los Angeles 90095, California, USA
    J Bone Joint Surg Br 88:255-60. 2006
    ..The Sauvé-Kapandji procedure combined with simple excision of osteochondromas can improve stability of the wrist, movement of the forearm and the radiological appearance...
  73. ncbi Validation of an HR-pQCT-based homogenized finite element approach using mechanical testing of ultra-distal radius sections
    Peter Varga
    Institute of Lightweight Design and Structural Biomechanics, Vienna University of Technology, Gusshausstrasse 27 29, Vienna, Austria
    Biomech Model Mechanobiol 10:431-44. 2011
    Osteoporotic (Colles' type) fractures of the distal radius occur relatively early in lifetime and could estimate risk of fracture of other, more endangered anatomical sites...
  74. ncbi Accuracy of pQCT for evaluating the aged human radius: an ashing, histomorphometry and failure load investigation
    M C Ashe
    Department of Family Practice, University of British Columbia, Suite 320 5950 University Blvd, Vancouver, British Columbia, Canada, V6T 1Z3
    Osteoporos Int 17:1241-51. 2006
    ..However, in a compromised osteoporotic bone, thin cortices and low scan resolution can limit accurate analysis...
  75. ncbi The dorsal horizon view: detecting screw protrusion at the distal radius
    Samuel James Joseph
    Department of Orthopaedics, Southern Health, Dandenong, Australia
    J Hand Surg Am 36:1691-3. 2011
    Extensor tendon injury after osteosynthesis of distal radius fractures is a well-documented complication...
  76. ncbi Bone density spatial patterns in the distal radius reflect habitual hand postures adopted by quadrupedal primates
    Biren A Patel
    Interdepartmental Doctoral Program in Anthropological Sciences, Stony Brook University, Stony Brook, NY 11794 4364, USA
    J Hum Evol 52:130-41. 2007
    ..g., magnitudes and patterns) in the subchondral cortical plate of bone of the distal radius can be used to evaluate load regimes experienced by the wrist joint in different hand postures...
  77. ncbi Comparison of surgical treatment and nonoperative management for radial longitudinal deficiency
    P P Kotwal
    Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India
    J Hand Surg Eur Vol 37:161-9. 2012
    ..Surgical treatment of radial longitudinal deficiency provides improvement in cosmesis, function and ease of performance of activities when compared with nonoperatively managed hands...
  78. ncbi An analysis of bone regeneration at a segmental bone defect by controlled release of bone morphogenetic protein 2 from a biodegradable sponge composed of gelatin and β-tricalcium phosphate
    N Fujita
    Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan
    J Tissue Eng Regen Med 6:291-8. 2012
    ....
  79. ncbi Long-term complications of distal radius bone grafts
    Jagruti C Patel
    University of Connecticut, Connecticut Children s Medical Center, Hartford, CT, USA
    J Hand Surg Am 28:784-8. 2003
    To assess long-term results and complications of cancellous bone graft taken from the distal radius.
  80. ncbi Radius bone strength in bending, compression, and falling and its correlation with clinical densitometry at multiple sites
    Eva Maria Lochmüller
    Frauenklinik Innenstadt, Ludwig Maximilians Universitat Munchen, Germany
    J Bone Miner Res 17:1629-38. 2002
    ..and nonsite-specific clinical densitometric techniques for predicting mechanical strength of the distal radius in different loading configurations...
  81. ncbi Discrimination of proximal hip fracture by quantitative ultrasound measurement at the radius
    M Weiss
    Endocrine Institute, Assaf Harofeh Medical Center, Zerifin, Israel
    Osteoporos Int 11:411-6. 2000
    ..reports suggested that of the different skeletal sites measured by this device, the distal third of the radius is the preferred measurement site for osteoporosis...
  82. ncbi Trabecular bone architecture in the distal radius using magnetic resonance imaging in subjects with fractures of the proximal femur. Magnetic Resonance Science Center and Osteoporosis and Arthritis Research Group
    S Majumdar
    Department of Radiology, and Department of Internal Medicine, University of California, San Francisco, California, USA
    Osteoporos Int 10:231-9. 1999
    To determine whether magnetic resonance (MR)-derived measures of trabecular bone architecture in the distal radius are predictive for prevalent hip fractures, 20 subjects with hip fractures and 19 age-matched postmenopausal controls were ..
  83. ncbi Hip fracture discrimination study: QUS of the radius and the calcaneum
    Didier Hans
    Division of Nuclear Medicine, Geneva University Hospital, Geneva, CH
    J Clin Densitom 6:163-72. 2003
    ..of technologically different QUS devices available on the market and, so far, no study has compared heel and radius QUS device for the discrimination of subjects with hip fractures...
  84. ncbi The spectrum of radial longitudinal deficiency: a modified classification
    M A James
    Department of Orthopaedic Surgery, Shriners Hospital Northern California, Sacramento 95817, USA
    J Hand Surg Am 24:1145-55. 1999
    ..that includes the spectrum of pathology affecting the radial side of the extremity, including deficiency of the radius, carpal abnormalities, and hypoplastic thumbs...
  85. ncbi Lengthening of the forearm by callus distraction
    M Abe
    Department of Orthopedic Surgery, Osaka Medical College, Takatsuki, Japan
    J Hand Surg Br 21:151-63. 1996
    ..distal ulna in five cases, enchondroma of the distal ulna in one, growth disturbance after fracture of the distal radius in one, radial club hand in one, congenital amputation of the forearm in one and congenital dislocation of the ..
  86. ncbi Thrombocytopenia-absent radius (TAR) syndrome: a clinical genetic series of 14 further cases. impact of the associated 1q21.1 deletion on the genetic counselling
    Ali Houeijeh
    Service de Génétique clinique Guy Fontaine, CHRU Lille, France
    Eur J Med Genet 54:e471-7. 2011
    Thrombocytopenia-absent radius Syndrome (TAR) is a rare congenital malformation syndrome of complicated transmission. 1q21.1 deletion is necessary but not sufficient for its expression...
  87. ncbi The use of frozen-allograft radial head replacement for treatment of established symptomatic proximal translation of the radius: preliminary experience in five cases
    R M Szabo
    Department of Orthopaedic Surgery, University of California, Davis, Sacramento 95817, USA
    J Hand Surg Am 22:269-78. 1997
    Five patients with disabling symptoms related to proximal translation (> 1 cm) of the radius following radial head excision (Essex-Lopresti lesion) were treated with implantation of a frozen-allograft radial head prosthesis...
  88. pmc Radial shortening following a fracture of the proximal radius
    Andrew D Duckworth
    Edinburgh Orthopaedic Trauma Unit, Edinburgh Royal Infirmary, Edinburgh, UK
    Acta Orthop 82:356-9. 2011
    ..We describe the range of radial shortening that occurs following a fracture of the proximal radius, as well as the short-term outcome in these patients.
  89. ncbi Absence of thumbs, A/hypoplasia of radius, hypoplasia of ulnae, retarded bone age, short stature, microcephaly, hypoplastic genitalia, and mental retardation
    Dagmar Wieczorek
    Institut fur Humangenetik, Universitatsklinikum Essen, Essen, Germany
    Am J Med Genet 108:209-13. 2002
    ..Having excluded major differential diagnoses, e.g. Fanconi anemia, RAPADILINO syndrome and VACTERL association, we hypothesize that this boy represents a new multiple congenital anomaly/mental retardation (MCA/MR) syndrome...
  90. doi Deformity correction with the Taylor spatial frame after growth arrest of the distal radius: a technical note on 2 cases
    Dominik Seybold
    Chirurgische Klinikund Poliklinik, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr Universitat Bochum, Germany
    Acta Orthop 79:571-5. 2008
  91. ncbi Does a volar locking plate provide equivalent stability as a dorsal nonlocking plate in a dorsally comminuted distal radius fracture?: a biomechanical study
    Utku Kandemir
    Department of Orthopaedics, University of California, San Francisco, CA 94110, USA
    J Orthop Trauma 22:605-10. 2008
    ..to compare the fixation afforded by a dorsal nonlocking plate with a volar locking plate in a fracture model simulating an extra-articular distal radius fracture with dorsal comminution (OTA [Orthopaedic Trauma Association] type 23-A3.2).
  92. ncbi Congenital radius deficiency: radiographic outcome and survivorship analysis
    M J Geck
    Department of Orthopaedic Surgery, University of California Los Angeles, USA
    J Hand Surg Am 24:1132-44. 1999
    The experience with congenital radius deficiency, or radial hemimelia, at the Shriners' Hospital for Children, Los Angeles Unit, was reviewed...
  93. ncbi Gender-specific pubertal changes in volumetric cortical bone mineral density at the proximal radius
    E Schoenau
    Children s Hospital, University of Cologne, Cologne, Germany
    Bone 31:110-3. 2002
    ..Our results therefore suggest that intracortical remodeling is lower in postpubertal females than in males...
  94. ncbi Association of larger holes in the trabecular bone at the distal radius in postmenopausal women with type 2 diabetes mellitus compared to controls
    Janet M Pritchard
    McMaster University, Hamilton, Ontario, Canada
    Arthritis Care Res (Hoboken) 64:83-91. 2012
    ..The study objective was to compare trabecular bone microarchitecture of postmenopausal women with type 2 DM and women without type 2 DM...
  95. ncbi Quantitative ultrasound of the tibia and radius in prepubertal and early-pubertal female athletes
    Bareket Falk
    Department of Physiology, Ribstein Center for Sport Medicine Sciences and Research, Wingate Institute, Netanya 42902, Israel
    Arch Pediatr Adolesc Med 157:139-43. 2003
    ..Physical exercise during childhood has been shown to enhance bone mineral density, thus reducing the risk of osteoporosis...
  96. ncbi Maternal thrombocytopenia-absent radius syndrome complicated by severe pre-eclampsia
    Joseph R Wax
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Maine Medical Center, Portland, Maine, USA
    J Matern Fetal Neonatal Med 22:175-7. 2009
    Thrombocytopenia-absent radius (TAR) syndrome affects 0.5-1/100,000 live births...
  97. pmc Calcification of the intervertebral discs and curvature of the radius and ulna: a radiographic survey of Finnish miniature dachshunds
    A Lappalainen
    Faculty of Veterinary Medicine, Department of Clinical Veterinary Sciences, University of Helsinki, Finland
    Acta Vet Scand 42:229-36. 2001
    ..The front legs were also radiographed in order to evaluate the curvature of the radius and ulna. Calcified discs were found in 75.9% of the longhaired miniature dachshunds and in 86...
  98. ncbi Assessment of volume fraction and fabric in the distal radius using HR-pQCT
    P Varga
    Institute of Lightweight Design and Structural Biomechanics, Vienna University of Technology, Gusshausstrasse 27 29, A 1040 Vienna, Austria
    Bone 45:909-17. 2009
    ..Four cadaveric human forearms were scanned with HR-pQCT and the dissected radius epiphyses with microCT...
  99. ncbi Cortical porosity is higher in boys compared with girls at the distal radius and distal tibia during pubertal growth: an HR-pQCT study
    Kyle K Nishiyama
    Schulich School of Engineering, University of Calgary, Calgary, Canada
    J Bone Miner Res 27:273-82. 2012
    ..the sex- and maturity-related differences in bone microstructure and estimated bone strength at the distal radius and distal tibia in children and adolescents...
  100. ncbi Site specificity of bone architecture between the distal radius and distal tibia in children and adolescents: An HR-pQCT study
    Danmei Liu
    Department of Orthopaedics, University of British Columbia, Vancouver, BC, Canada
    Calcif Tissue Int 87:314-23. 2010
    ..The purpose of this study was to compare bone architecture between distal radius and distal tibia...
  101. ncbi Radius neck-to-humerus trochlea transposition for elbow reconstruction after resection of the proximal ulna: report of 2 cases
    Scott F M Duncan
    Department of Orthopedics, Mayo Clinic, Scottsdale, AZ 85259, USA
    J Hand Surg Am 33:1384-7. 2008
    ..The purpose of our report was to retrospectively review the outcome of the radius neck-to-humerus trochlea transposition after wide resection of malignant forearm tumors in 2 patients...

Research Grants75

  1. Asymmetric flow FFF and Composition Gradient/Light Scattering System
    Ewa Folta Stogniew; Fiscal Year: 2007
    ..molar mass in a single experiment: the molar mass is determined from a static LS measurement and the hydrodynamic radius is determined from AFFF elution time and from dynamic LS measurements...
  2. FUNCTION AND REGULATION OF AP-2 IN SKELETAL DEVELOPMENT
    Zhengmin Huang; Fiscal Year: 2007
    ..knockout results in skeletal defects in craniofacial and limb bud development (shortened limb length and loss of radius) as well as other embryonic developmental defects (neural tube closure, body wall formation, and eye formation)...
  3. Novel TIRF microscopy analyzing trafficking & signaling at the cell cortex
    Derek Toomre; Fiscal Year: 2009
    ..Consistent with the recovery act's goal, this funding will provide full-time summer employment for 4 undergraduate students and accelerate scientific achievement of the parent DP2 award...
  4. VITamin D and OmegA-3 TriaL: Effects on Bone Structure and Architecture
    MERYL SUSAN LEBOFF; Fiscal Year: 2013
    ..in bone turnover;Aim 2: High-dose vitamin D3 will improve: vBMD and bone structure and architecture at the distal radius and tibia, as assessed by HR-pQCT and bone strength estimates;Aim 3: High-dose vitamin D3 will result in lower (a) ..
  5. Inflammasome Activation in Complex Regional Pain Syndrome
    Wade S Kingery; Fiscal Year: 2013
    ..provided by applicant): Complex Regional Pain Syndrome Type I (CRPS I) is a frequent sequela of distal tibia and radius fractures and limb surgery though it can occur even after minor injuries...
  6. Bone Microarchitecture: The Framingham Osteoporosis Study
    Douglas P Kiel; Fiscal Year: 2013
    ..We will measure volumetric BMD, bone microarchitecture and bone strength at the distal radius and distal tibia using three-dimensional HR-pQCT in 1,411 women and 1,154 men in the Framingham Offspring Cohort...
  7. Traffic and Respiratory Health
    Brian P Leaderer; Fiscal Year: 2013
    ..Our goal is to estimate levels of pollution due to traffic within buffers (e.g. a 500 m radius) around a residence within a neighborhood, i.e., residential-scale pollution levels...
  8. The interaction of anabolic and antiresorptive agents in osteoporosis therapy
    Joy Tsai; Fiscal Year: 2013
    ..Specifically, high-resolution peripheral quantitative computed tomography of the distal tibia and radius will be used to compare the effects of combination TPTD and DMAB therapy versus each individual agent on cortical ..
  9. Modeling TAR Microdeletion Syndrome in Mouse
    Christa Lese Martin; Fiscal Year: 2013
    ..One such low-penetrance CNV syndrome is Thrombocytopenia-absent radius (TAR) syndrome...
  10. The role of Twist family bHLH factors in limb morphogenesis
    Anthony B Firulli; Fiscal Year: 2013
    ..ablation of Hand2 within the limb indicates that Hand2 plays a role in limb antero-posterior (AP) axis formation (radius and ulna, thumb to little finger)...
  11. MicroXCT-200 High Resolution 3D X-ray Microscope
    MOHAMMED PERVEZ AKHTER; Fiscal Year: 2013
    ..Users (seven NIH funded projects) and seven Minor/Other users from five major institutions within a 200- mile radius of Creighton University: Boys Town National Hospital (1 user), Creighton University (3 users), U of Missouri ..
  12. University of New Mexico Cancer Center Support
    Cheryl L Willman; Fiscal Year: 2013
    ..As the only NCI Cancer Center within a 500 mile radius, the special characteristics of the UNM Cancer Center include: the multiethnic and multicultural populations that ..
  13. Serotonin Reuptake Inhibitors and Bone Mineralization in Adolescents
    Chadi A Calarge; Fiscal Year: 2013
    ..mineral density of the lumbar spine and whole body will be measured using dual x-ray absorptiometry and of the radius using peripheral quantitative computerized tomography...
  14. MOLECULAR MECHANISMS OF CFTR FUNCTION
    John R Riordan; Fiscal Year: 2013
    ..rather than influencing ATP hydrolysis, promotes release of unhydrolysed ATP from NBD1 and also increases the radius of gyration of the largely unstructured R domain which in turn alters the conformation of membrane spanning ..
  15. Computational Biomechanics for Prediction of Osteoporotic Vertebral Fracture Risk
    Chamith Sudesh Rajapakse; Fiscal Year: 2013
    ..The proposed study makes use of mMR images of distal radius and distal tibia and midline-sagittal spine MR images in ninety eight patients with osteoporosis...
  16. Light Scattering & Flourescence Study of Sugar Solutions as Cryoprotective Agents
    DAVID LEE SIDEBOTTOM; Fiscal Year: 2010
    ..be used to determine the degree of bonding of sugars to the protein through changes observed in the hydrodynamic radius of these agglomerates as they diffuse in the solution...
  17. Development of 18F-Labeled Agonist PET Probes for Quantifying 5-HT1A Receptors
    MAJO VATTOLY JOSEPH; Fiscal Year: 2010
    ..The F-18 tracer can be shipped to multiple medical centers that are within a radius of 4 hours from the production site...
  18. FSH as a biomarker of bone strength in younger postmenopausal women
    Margaret L Gourlay; Fiscal Year: 2010
    ..unadjusted correlation between the multiplicative variable FSH-years and areal bone density in the distal radius. In the proposed project, we will also test for correlations between FSH-related variables and pQCT measures of ..
  19. Translation of District Sun Safe Policies to Schools
    KIM DANIEL REYNOLDS; Fiscal Year: 2013
    ..Participating schools (N=142) will be recruited from 30 school districts within a radius of 100 miles of Claremont, California, a city in eastern Los Angeles County approximately 35 miles from downtown ..
  20. Mechanical System for Low Force Fatigue Tissue Testing
    Dawn M Elliott; Fiscal Year: 2010
    ..existing mechanical testing equipment within the Penn Center for Musculoskeletal Disorders or within a 200 mile radius of the University of Pennsylvania...
  21. MRI-Based Assessment of Structural and Mechanical Implications of Osteoporosis
    Felix W Wehrli; Fiscal Year: 2013
    ..and sub-volume trabecular bone elastic and shear moduli) derived from in vivo ?MR images at the distal tibia and radius, are associated with structural parameters expressing scale, topology and orientation at the measurement sites, ..
  22. Clinical Bone Mechanics Using HR-pQCT and MRI
    Felix W Wehrli; Fiscal Year: 2013
    ..Morphological measurements and 5FE predictions of stiffness and failure load of the distal tibia and radius from ex vivo 5MRI and HR-pQCT correlate highly with those from 5CT and direct mechanical testing, and, furthermore,..
  23. A Study of Reduced Bone Quality as a Cause of Fractures
    Robert Roy Recker; Fiscal Year: 2012
    ..We will obtain hip structural analyses from dual energy absorptiometry, magnetic resonance images of the radius, quantitative computed tomography of the hip and spine, and two transilial bone biopsy specimens from each subject...
  24. Reducing Health Disparity in AA Women: Physical Activity Adherence
    JoEllen Wilbur; Fiscal Year: 2013
    ..and no history of myocardial infarction, stroke, or insulin-dependent diabetes will be recruited within a 3-mile radius of the community health care centers...
  25. BIOCHEMICAL AND BIOPHYSICAL NATURE OF CLAUDIN-16 AND CLAUDIN-19 CHANNELS
    Jianghui Hou; Fiscal Year: 2013
    ..These studies will measure the paracellular flux of a continuous series of PEG oligomers (of radius 2.8 - 7 [unreadable]) to unveil the size selectivity of claudin-16 and claudin-19 channels...
  26. Cortical Bone Porosity Identifies Diabetes Subjects With Fragility Fractures
    Thomas M Link; Fiscal Year: 2010
    ..resolution (voxel size) to visualize cortical and trabecular bone structure in vivo at the distal tibia and radius. Our research group has acquired extensive experience with this technique, in particular concerning image post-..
  27. Bone Fracture Risk Assessment Through Bound - and Pore - Water MRI
    Mark D Does; Fiscal Year: 2013
    ..along with DXA and qCT, will be applied to multiple cadaveric bone sites (including the femoral neck and distal radius)...
  28. The Bone Trial of the Testosterone Trial
    Peter J Snyder; Fiscal Year: 2013
    ..hip by finite element analysis determined from the QCT data;areal BMD of the lumbar spine, proximal hip and distal radius by DXA;serum markers of bone turnover;and clinical fractures...
  29. Laser endoscopy for guided biopsy in the bile duct
    Eric J Seibel; Fiscal Year: 2010
    ..at the tip of a catheter, making a rigid tip of only 9-mm and a rugged flexible shaft with a 6-mm bending radius. Previously this catheterscope with distal-tip microscanner can acquire 600-line color images at 30 Hz (video rate)..
  30. An intramedullary device for less invasive surgical fixation of wrist fractures.
    Edward Diao; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The distal radius is one of the most common sites of bone fracture and is the most common fracture site in the upper extremity, accounting for approximately 10% of all fractures in adults...
  31. Multisite School-Based Evaluation of a Brief Screener for Underage Drinking
    Jonathan G Tubman; Fiscal Year: 2013
    ..of the screener vary according to the density of alcohol outlets within walking distance (a practical 1/4 mile radius) o each adolescent's home and school addresses, and according to Census-level poverty, affluence, residential ..
  32. Student Development at Chicago State University
    VENKATESWARA DEVI PRASAD POTLURI; Fiscal Year: 2013
    ..both the opportunity and the challenge of educating students who are mostly raised and educated within a ten-mile radius of the campus and are products of both an economically-disadvantaged background and a high- school education which ..
  33. Cyclic Versus Daily Teriparatide on Bone Mass, Microstructure and Strength
    Robert Lindsay; Fiscal Year: 2013
    ..teriparatide given daily for 2 years on BMD of the spine and hip by DXA and QCT and BMD and microstructure of the radius and tibia assessed by high resolution pQCT...
  34. Evidence-Based Research in Hand Surgery
    Kevin C Chung; Fiscal Year: 2012
    ..to develop a multidisciplinary research portfolio at the University of Michigan to study the treatment of distal;radius fracture by applying epidemiology and clinical trial principles...
  35. Uranium in Food Grown in an American Indian Community
    Christine Samuel-Nakamura; Fiscal Year: 2013
    ..2 km) radius from the central part of abandoned U mines, tailings/waste piles, and structures...
  36. Three-dimensional structure-function relationships in glaucoma from SD-OCT
    Milan Sonka; Fiscal Year: 2013
    ..the focal structural-functional correlation in the retina covered by the Humphrey 24-2 perimetry test (24 degree radius visual field) by comparing 24-2 thresholds with their corresponding structural indices derived from registered ..
  37. Request for Leica High-pressure Freezer and Automated Freeze-substitution System
    SCOT CHARLES KUO; Fiscal Year: 2010
    ..Because no equivalent instrument is available for a 55-mile radius, many time-sensitive studies proposed by major users would have been precluded by the extreme delicacy of frozen ..
  38. A Clinical and Computational Study to Improve Brachiocephalic Fistula Outcomes
    MARY SUSAN HAMMES; Fiscal Year: 2013
    ..Aim 2: In the same subjects as Aim 1, measure venous radius and cephalic arch angle over time and derive predictive functions of time, inlet pressure, anastomosis type, and ..
  39. St. Jude/Memphis IMPAACT Clinical Trials Unit (Composite)
    PATRICIA MICHELE FLYNN; Fiscal Year: 2013
    ..is a large Southern urban area that provides tertiary health care for individuals in an approximately 200-mile radius in the states of Tennessee, Mississippi, Missouri, and Arkansas...
  40. St. Jude/Memphis IMPAACT Clinical Trials Unit (Composite)
    PATRICIA MICHELE FLYNN; Fiscal Year: 2011
    ..is a large Southern urban area that provides tertiary health care for individuals in an approximately 200-mile radius in the states of Tennessee, Mississippi, Missouri, and Arkansas...
  41. OSTEOARTHRITIS & OSTEOPOROSIS IN ELDERLY WOMAN
    Michael Nevitt; Fiscal Year: 1992
    ..Therefore, we will study bone mass in the hip in relation to hip OA, bone mass in the radius in relation to hand OA, and bone mass in the spine in relation to spine OA...
  42. IMMUNITY AND INFECTION
    James B Kaper; Fiscal Year: 2013
    ..All faculty members are located within a three-block radius on the University of Maryland Baltimore campus...
  43. Actin filament elasticity and actin-binding protein function
    Enrique M De La Cruz; Fiscal Year: 2013
    ..The proposed activities will provide an explicit link between the microscopic properties (filament radius, monomer dimensions, buried subunit interface area, lateral or longitudinal contacts), the global mechanical ..
  44. Development of an Osseo-Magnetic Link for Control of Prosthetic Limb Rotation
    JULIO JOSE SANTOS MUNNE; Fiscal Year: 2010
    ..of proprioception will be achieved by implanting a permanent magnet into the distal end of the residual radius bone, and magnetic field sensors into the surrounding prosthetic socket...
  45. Tensor Scale-based Methods for Assessment of Trabecular Bone Quality
    PUNAM KUMAR SAHA; Fiscal Year: 2012
    ..Most osteoporotic fractures occur at sites rich in TB (vertebrae, radius, proximal femur)...
  46. Zonular Capture Accommodative-Disaccommodative Intraocular Lens System
    PAUL LEON KAUFMAN; Fiscal Year: 2013
    ..Such optics can be rigid, single or double optics, moving axially, or flexible optics that can change the radius of curvature. Depending on the optic(s) chosen for the system, it is anticipated that a range 3.5-9...
  47. A Biacore T200 for Molecular Interaction Studies at the University of Miami
    Ralf Landgraf; Fiscal Year: 2012
    ..is in stark contrast to the absence of any such equipment with open access within a several hundred mile radius of UM...
  48. Struct. Invest. of Hsp70 and TGFb by Solution Studies and High-Perform. Comput.
    EMRE H BROOKES; Fiscal Year: 2013
    ..Small angle X-ray and/or neutron scattering profiles, radius of gyration and hydrodynamic molecular parameters, such as the sedimentation coefficient, translational and ..
  49. Socioeconomic Status and Post-Injury Quality of Life and Functional Ability
    Ben L Zarzaur; Fiscal Year: 2012
    ..these aims 250 moderately to severely injured persons admitted to the only Level I Trauma Center for a 150-mile radius to Memphis, Tennessee will be followed for one year...
  50. A prospective study of human bone adaptation using a novel in-vivo loading model
    Karen L Troy; Fiscal Year: 2013
    ..for the first tim in humans, the relationship between strain magnitude and strain rate to changes in distal radius bone structure and strength...
  51. Micro-Mechanical Modeling of Trabecular Bone
    X Edward Guo; Fiscal Year: 2013
    ..fractures, and (2) develop computationally efficient, patient-specific P-R models of whole distal tibia and radius bone segments, which will translate our findings to clinical HR-pQCT research, and (3) establish relationships in ..
  52. Development of Fiber Optic Biosensors for Detection of Cancer Molecular Markers
    Rakesh Kapoor; Fiscal Year: 2010
    ..on enhancement of fluorescence signal by optimization of probe parameters (tapered angle, taper length and probe radius), and adoption of existing sandwich immunoassay techniques to fiber optic probes...
  53. Bar Domains and Neuronal Membrane Structure
    Tobias Meyer; Fiscal Year: 2013
    ..available in vitro assays and structural studies of proteins with membrane binding domains can determine the radius of the membrane curvature that results from the formation of oligomers by curvature sensing proteins...
  54. Direct visualization of the FG nups, the selective gating for nuclear transport
    Loren E Hough; Fiscal Year: 2010
    ..We have covalently attached the FG repeat portion of two archetypal FG nups to 40 nm radius latex beads in an orientation and density comparable to that found in the NPC...
  55. Mentored Experience in Research, Instruction, and Teaching (MERIT) Program
    Lisa M Schwiebert; Fiscal Year: 2013
    ..Birmingham (UAB) in partnership with Miles College and Stillman College;all schools are located within a 50 mile radius. The proposed MERIT Program will include 3 years of concurrent research training and teaching instruction...
  56. Accurate Mass Analysis of Singly-Charged Intact Proteins
    Peter T A Reilly; Fiscal Year: 2010
    ..We have recently created an inlet and large-radius frequency-adjusted linear quadrupole ion trap that is capable of capturing large quantities (>100 million ions) ..
  57. An analysis of environmental risk factors for obesity
    Walker Poston; Fiscal Year: 2007
    ..75 mile radius around the perimeter of each block-group)...
  58. DULUTH COMMUNITY CLINICAL ONCOLOGY PROGRAM
    Daniel A Nikcevich; Fiscal Year: 2013
    ..Geographically, the Duluth CCOP covers a large area including urban and rural areas, with a radius of over 150 miles from Duluth...
  59. Growth of Trabecular Bone Damage Due to Off-axis Loads
    Glen Niebur; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Fractures of the proximal femur and distal radius, both regions where trabecular bone has a major load bearing function, are common...
  60. MBRS SCORE Program at Chicago State University
    RACHEL W LINDSEY; Fiscal Year: 2010
    ..both the opportunity and the challenge of educating students who are mostly raised and educated within a ten-mile radius of the campus and are products of both an economically-disadvantaged background and often a high-school education ..
  61. RADIO-ULNAR LOAD SHARING IN THE CADAVER FOREARM
    Keith Markolf; Fiscal Year: 2003
    The overall objective of the proposed in vitro studies is to measure proximal and distal load-sharing between the radius and ulna before and after surgical procedures designed to alter load transmission pathways...
  62. PLATELET AGGLUTINATION IN THROMBOTIC MICROANGIOPATHY
    ERIC LIAN; Fiscal Year: 1993
    ..1) Further elucidation of the physicochemical properties of PAP p37 and p58 including the molecular weight, Stokes Radius, frictional ratio, sedimentation coefficient, isoelectric point, amino acid composition, carbohydrate, and lipid ..
  63. STABILITY ANALYSIS OF THE DISTAL RADIO ULNAR JOINT
    Richard Berger; Fiscal Year: 1999
    ..to this Aim include: 1a) the volar radio-ulnar ligament stabilizes the DRUJ against volar displacement of the radius relative to the ulna in all positions of forearm rotation; 1b) the dorsal radio-ulnar ligament stabilizes the DRUJ ..
  64. The effect of light rail transit on physical activity: a natural experiment
    Brian E Saelens; Fiscal Year: 2012
    ..Using a case-control longitudinal panel controlled design, 1000 adults living either close to (within 1 mile radius;case) or far from (control) an LRT station who are similar demographically and in initial neighborhood built ..
  65. LONGITUDINAL STUDY OF BONE DENSITY IN ANOREXIA NERVOSA
    MICHAEL PERTSCHUK; Fiscal Year: 1993
    ..by means of dual photonabsorpticmetry of the lumbar spine and single photon absorptiometry of the non-dominant mid-radius. Baseline values will be obtained including serum pregnancy test, estradiol, 25-OH-Vit D, Ca, inorganic PO4, alk ..
  66. BAND 3 N-TERMINAL AA (10-16) AND DEOXY S POLYMERIZATION
    John Harris; Fiscal Year: 1990
    ..protrude approximately 27 angstrom outside the molecule to occupy and occlude a hemispheric volume of 27 angstrom radius around the 2,3-DPG binding site of the betaS chains and 2) the protruding portion of the peptide will, by sheer ..
  67. A THz Resonator for Solid-State DNP-NMR Spectroscopy
    JAGADISHWAR RAO SIRIGIRI; Fiscal Year: 2013
    ..The common assumption is, that the transverse size of a fundamental mode resonator (radius ~0...
  68. Gallium, a potential new therapeutic for CF airway infections
    Pradeep K Singh; Fiscal Year: 2010
    ..Ga has a nearly identical ionic radius as Fe, and many biologic systems are unable to distinguish Ga from Fe...
  69. MULTISCAN PHOTON ABSORPTIOMETRY & OSTEOPOROTIC FRACTURE
    Wilson Hayes; Fiscal Year: 1991
    Approximately 1.3 million osteoporotic fractures of the vertebrae hip, and distal radius occur each year in the U.S., with estimated annual costs in excess of $10 billion...
  70. NONINVASIVE ASSESSMENT OF TRABECULAR ARCHITECTURE
    Sharmila Majumdar; Fiscal Year: 1999
    ..quantification of trabecular architecture in cubic specimen of human trabecular bone from the lumbar spine, distal radius, calcaneus and proximal femur and relate the fractal characteristics of the radiographs measured in three ..
  71. Ultra-soft atomic force microscope (USAFM) technology using nano-cantilevers for
    MEHDI YAZDANPANAH; Fiscal Year: 2009
    ..A sharp molecular tip (e.g. Fibrinogen fiber) will be grown on each nano-cantilever to provide a small tip radius (5-10 nm), converting the bare nano-cantilever into high-resolution ultra-soft- probes (USPs) for USAFM. 2...
  72. BIOMECHANICS OF VERTEBRAL FRACTURES IN OSTEOPOROSIS
    WHITSON EDWARDS; Fiscal Year: 1991
    ..associated with losses in bone volume and increases in the risk of spontaneous fractures of the spine, hip, and radius. Millions of post-menopausal women are particularly at risk...
  73. Neuroblastoma-Specific MRI Contrast Agents
    Stephan Voss; Fiscal Year: 2007
    ..MIONs are ultrasmall (approximately 20 nm hydrodynamic radius) dextran-coated iron oxide superparamagnetic colloids that alter T2-weighted MRI contrast enhancement...
  74. EPIDEMIOLOGY OF HORMONES AND OSTEOPOROSIS
    Lewis Kuller; Fiscal Year: 1991
    ..of endogenous sex steroid hormone concentrations to appendicular cortical bone, specifically the dominant radius, in 174 normal postmenopausal woman, mean age 58 years...
  75. PATHOBIOLOGY OF GLOMERULAR INJURY IN TYPE II DIABETES
    Timothy Meyer; Fiscal Year: 1993
    ..each, reveals that GFR is elevated by 14% and that glomerular pore size distribution is shifted to pores of larger radius at approximately 1 year after the onset of type II diabetes (Group 2)...