psoas muscles

Summary

Summary: A powerful flexor of the thigh at the hip joint (psoas major) and a weak flexor of the trunk and lumbar spinal column (psoas minor). Psoas is derived from the Greek "psoa", the plural meaning "muscles of the loin". It is a common site of infection manifesting as abscess (PSOAS ABSCESS). The psoas muscles and their fibers are also used frequently in experiments in muscle physiology.

Top Publications

  1. pmc Structural transients of contractile proteins upon sudden ATP liberation in skeletal muscle fibers
    Jun ichi Wakayama
    Life and Environment Division, SPring 8, Japan Synchrotron Radiation Research Institute, Hyogo 679 5198, Japan
    Biophys J 87:430-41. 2004
  2. ncbi Lumbar plexus and psoas major muscle: not always as expected
    Lukas Kirchmair
    Department of Anesthesiology and Critical Care Medicine, Innsbruck Medical University, Innsbruck, Austria
    Reg Anesth Pain Med 33:109-14. 2008
  3. pmc Regional Myosin heavy chain distribution in selected paraspinal muscles
    Gilad J Regev
    Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, CA 92093, USA
    Spine (Phila Pa 1976) 35:1265-70. 2010
  4. pmc Anatomy of the psoas muscle and lumbar plexus with respect to the surgical approach for lateral transpsoas interbody fusion
    Christopher K Kepler
    Spine and Scoliosis Service, Department of Orthopaedic Surgery, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA
    Eur Spine J 20:550-6. 2011
  5. pmc Length-dependent activation in three striated muscle types of the rat
    John P Konhilas
    Department of Physiology and Biophysics and Cardiovascular Sciences Program, College of Medicine, University of Illinois at Chicago, 60612, USA
    J Physiol 544:225-36. 2002
  6. ncbi Psoas muscle attenuation measurement with computed tomography indicates intramuscular fat accumulation in patients with the HIV-lipodystrophy syndrome
    Martin Torriani
    Division of Musculoskeletal Radiology, Massachusetts General Hospital, Boston, MA 02114, USA
    J Appl Physiol (1985) 95:1005-10. 2003
  7. pmc Development of a porcine skeletal muscle cDNA microarray: analysis of differential transcript expression in phenotypically distinct muscles
    Qianfan Bai
    Laboratory of Veterinary Molecular Medicine, Department of Veterinary Pathology, University of Glasgow, Bearsden Road, Glasgow G61 1QH, UK
    BMC Genomics 4:8. 2003
  8. ncbi An anatomical study of the lumbosacral plexus as related to the minimally invasive transpsoas approach to the lumbar spine
    David M Benglis
    Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA
    J Neurosurg Spine 10:139-44. 2009
  9. ncbi Defining the safe working zones using the minimally invasive lateral retroperitoneal transpsoas approach: an anatomical study
    Juan S Uribe
    Department of Neurological Surgery, University of South Florida, Tampa, Florida 33606, USA
    J Neurosurg Spine 13:260-6. 2010
  10. ncbi The relationship of intrapsoas nerves during a transpsoas approach to the lumbar spine: anatomic study
    Daniel K Park
    Rush University Medical Center, Chicago, IL 60612, USA
    J Spinal Disord Tech 23:223-8. 2010

Research Grants

Detail Information

Publications193 found, 100 shown here

  1. pmc Structural transients of contractile proteins upon sudden ATP liberation in skeletal muscle fibers
    Jun ichi Wakayama
    Life and Environment Division, SPring 8, Japan Synchrotron Radiation Research Institute, Hyogo 679 5198, Japan
    Biophys J 87:430-41. 2004
    ..These results suggest that the interplay between the reattached active myosin heads and the thin filament is responsible for the prolonged active contraction in the presence of ADP...
  2. ncbi Lumbar plexus and psoas major muscle: not always as expected
    Lukas Kirchmair
    Department of Anesthesiology and Critical Care Medicine, Innsbruck Medical University, Innsbruck, Austria
    Reg Anesth Pain Med 33:109-14. 2008
    ..The present study was carried out to detect anatomical variants regarding the topographical relation between the lumbar plexus and the psoas major muscle as well as lumbar plexus anatomy at the L4-L5 level...
  3. pmc Regional Myosin heavy chain distribution in selected paraspinal muscles
    Gilad J Regev
    Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, CA 92093, USA
    Spine (Phila Pa 1976) 35:1265-70. 2010
    ..Cross-sectional study with repeated measures design...
  4. pmc Anatomy of the psoas muscle and lumbar plexus with respect to the surgical approach for lateral transpsoas interbody fusion
    Christopher K Kepler
    Spine and Scoliosis Service, Department of Orthopaedic Surgery, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA
    Eur Spine J 20:550-6. 2011
    ..Further study will establish the clinical relevance of these measurements and the ability of neurovascular structures to be retracted without significant injury...
  5. pmc Length-dependent activation in three striated muscle types of the rat
    John P Konhilas
    Department of Physiology and Biophysics and Cardiovascular Sciences Program, College of Medicine, University of Illinois at Chicago, 60612, USA
    J Physiol 544:225-36. 2002
    ....
  6. ncbi Psoas muscle attenuation measurement with computed tomography indicates intramuscular fat accumulation in patients with the HIV-lipodystrophy syndrome
    Martin Torriani
    Division of Musculoskeletal Radiology, Massachusetts General Hospital, Boston, MA 02114, USA
    J Appl Physiol (1985) 95:1005-10. 2003
    ..Further studies are needed to assess the mechanisms and consequences of intramuscular lipid accumulation in HIV-infected patients...
  7. pmc Development of a porcine skeletal muscle cDNA microarray: analysis of differential transcript expression in phenotypically distinct muscles
    Qianfan Bai
    Laboratory of Veterinary Molecular Medicine, Department of Veterinary Pathology, University of Glasgow, Bearsden Road, Glasgow G61 1QH, UK
    BMC Genomics 4:8. 2003
    ..This information is not only important for understanding basic muscle biology but also provides underpinning knowledge for enhancing the efficiency of livestock production...
  8. ncbi An anatomical study of the lumbosacral plexus as related to the minimally invasive transpsoas approach to the lumbar spine
    David M Benglis
    Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA
    J Neurosurg Spine 10:139-44. 2009
    ....
  9. ncbi Defining the safe working zones using the minimally invasive lateral retroperitoneal transpsoas approach: an anatomical study
    Juan S Uribe
    Department of Neurological Surgery, University of South Florida, Tampa, Florida 33606, USA
    J Neurosurg Spine 13:260-6. 2010
    ..The authors undertook this anatomical cadaveric dissection study to define the anatomical safe zones relative to the disc spaces for prevention of nerve injuries during the lateral retroperitoneal transpsoas approach...
  10. ncbi The relationship of intrapsoas nerves during a transpsoas approach to the lumbar spine: anatomic study
    Daniel K Park
    Rush University Medical Center, Chicago, IL 60612, USA
    J Spinal Disord Tech 23:223-8. 2010
    ..A cadaveric study...
  11. ncbi Endoscopic lateral transpsoas approach to the lumbar spine
    Darren L Bergey
    Cedars Sinai Institute for Spinal Disorders, Los Angeles, California, USA
    Spine (Phila Pa 1976) 29:1681-8. 2004
    ..A description of a novel surgical approach to the lumbar spine and a prospective evaluation of the early surgical outcomes...
  12. ncbi The function of the psoas major muscle: passive kinetics and morphological studies using donated cadavers
    Masaharu Yoshio
    Department of Physical Therapy, School of Health Sciences, Sapporo Medical University, Minami 1 Nishi 17, Chuo Ku, Sapporo, Hokkaido 060 8556, Japan
    J Orthop Sci 7:199-207. 2002
    ....
  13. ncbi A rare cause of flank mass: psoas abscess due to extensive primary thoracolumbar tuberculous spondylodiskitis
    H T Sanal
    Department of Radiology, Gulhane Military Medical School, 06018, Etlik, Ankara, Turkey
    AJNR Am J Neuroradiol 27:1735-7. 2006
    ..We report multidetector CT and MR imaging findings of a psoas abscess secondary to primary tuberculous spondylodiskitis of the spine from the T3 to L2 vertebrae, which presented as a flank mass...
  14. ncbi Psoas abscess: a diagnostic dilemma
    Nabil A Ebraheim
    Department of Orthopaedic Surgery, University of Toledo Medical Center, Toledo, OH 43614, USA
    Am J Orthop (Belle Mead NJ) 37:E11-3. 2008
  15. ncbi Psoas and quadratus lumborum muscle asymmetry among elite Australian Football League players
    J Hides
    Division of Physiotherapy, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, 4072 Queensland, Australia
    Br J Sports Med 44:563-7. 2010
    ..In this study, asymmetry relative to the preferred kicking leg was determined if it exists for the psoas and quadratus lumborum muscles among elite Australian Football League (AFL) players...
  16. ncbi Iliopsoas tenotomy at the lesser trochanter versus at the pelvic brim in ambulatory children with cerebral palsy
    Gad M Bialik
    Sheba Medical Center, Tel Hashomer, Israel
    J Pediatr Orthop 29:251-5. 2009
    ....
  17. ncbi Robotic-assisted laparoscopic ureteral reimplantation with psoas hitch: a multi-institutional, multinational evaluation
    Nilesh N Patil
    Center for Robotics and Computer Assisted Surgery, Ohio State University, Columbus, Ohio 43210, USA
    Urology 72:47-50; discussion 50. 2008
    ..To report the collective experience of three multinational institutions with the use of robotics to evaluate and treat complex distal ureteral obstruction...
  18. pmc Thick-filament strain and interfilament spacing in passive muscle: effect of titin-based passive tension
    Thomas Irving
    Department of Biological, Chemical and Physical Sciences, Illinois Institute of Technology, Chicago, Illinois, USA
    Biophys J 100:1499-508. 2011
    ..This difference can be explained by the fact that thick filaments are more compliant at low tension (passive muscle) than at high tension (tetanic tension). The implications of our findings are discussed...
  19. ncbi Femoral nerve palsy. An unusual complication of anterior lumbar interbody fusion
    S L Papastefanou
    Harlow Wood Orthopaedic Hospital, Notts, United Kingdom
    Spine (Phila Pa 1976) 19:2842-4. 1994
    ..In the patients described no other reasons for direct or indirect injury were identified. CONCLUSION. Although uncommon, the complication should be kept in mind. It can be avoided by intraoperative hip flexion...
  20. pmc Endothermic force generation, temperature-jump experiments and effects of increased [MgADP] in rabbit psoas muscle fibres
    M E Coupland
    Muscle Contraction Group, Department of Physiology, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK
    J Physiol 567:471-92. 2005
    ....
  21. ncbi Anatomy, pathology, imaging and intervention of the iliopsoas muscle revisited
    Carmel G Cronin
    Department of Radiology, University College Hospital, Galway, Ireland
    Emerg Radiol 15:295-310. 2008
    ..We review the anatomy, clinical presentation and common imaging findings of iliopsoas disease as it presents through the emergency room...
  22. ncbi Effects of intramuscular psoas lengthening on pelvic and hip motion in patients with spastic diparetic cerebral palsy
    Mauro C Morais Filho
    Gait Analysis Laboratory, AACD, Sao Paulo, Brazil
    J Pediatr Orthop 26:260-4. 2006
    ..The use of external assistive devices in patients with balance problems may lead to increased anterior pelvic tilt as well as reduction of hip extension at terminal stance...
  23. pmc Psoas muscle and lumbar spine stability: a concept uniting existing controversies. Critical review and hypothesis
    L Penning
    University Hospital Groningen, The Netherlands
    Eur Spine J 9:577-85. 2000
    ..The presence of multiple PM fascicles, all of about equal length, and attaching to all LS levels, facilitates this function...
  24. pmc Dynamics of individual sarcomeres during and after stretch in activated single myofibrils
    Dilson E Rassier
    Department of Bioengineering, University of Washington, Seattle, WA 98195, USA
    Proc Biol Sci 270:1735-40. 2003
    ..Sarcomeres never lengthened to a point beyond thick and thin filament overlap. We conclude that sarcomeres are non-uniform but generally stable on the descending limb of the force-length relationship...
  25. ncbi The hip or not
    J Hamilton
    Centre for Rheumatic Diseases, Glasgow Royal Infirmary, 84 Castle Street, Glasgow G4 OSF, UK
    J Rheumatol 28:1398-400. 2001
    ..Pathologies within the ileopsoas compartment can present as hip pain and as such can be mistaken for diseases of the hip joint. Radiological investigations are useful in helping to differentiate between these pathologies...
  26. pmc Calcium regulation of tension redevelopment kinetics with 2-deoxy-ATP or low [ATP] in rabbit skeletal muscle
    M Regnier
    Department of Bioengineering, University of Washington, Seattle 98195, USA
    Biophys J 74:2005-15. 1998
    ..Moreover, k(tr) was decreased relative to control at P > 0.75Po, but was elevated at P < 0.75Po. These data demonstrate that the cross-bridge cycling rate dominates k(tr) at maximum but not submaximum levels of Ca(2+) activation...
  27. pmc Troponin C modulates the activation of thin filaments by rigor cross-bridges
    P W Brandt
    Department of Anatomy and Cell Biology, Columbia University, New York, New York 10032, USA
    Biophys J 72:2262-7. 1997
    ..Comparison of the structures of fTnC, CaM[3,4TnC], and cTnC indicates that the critical region for this property lies in the central helix or N-terminal domain, including EF hand motifs 1 and 2...
  28. pmc Strong binding of myosin increases shortening velocity of rabbit skinned skeletal muscle fibres at low levels of Ca(2+)
    D R Swartz
    Department of Anatomy, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Physiol 533:357-65. 2001
    ....
  29. ncbi Psoas hitch ureteral reimplantation in adults--analysis of a modified technique and timing of repair
    M Ahn
    Division of Urology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
    Urology 58:184-7. 2001
    ..Immediate repair may be safely undertaken as soon as the ureteral injury is recognized. Long-term sequelae are unusual in adults, even when using refluxing-type ureteral anastomoses...
  30. ncbi Modified psoas hitch with Lich-Gregoir onlay technique for the reconstruction of lower ureter during gynecologic or obstetric operations
    Lutfu Tahmaz
    Department of Urology, Gulhane Military Medical Academy, School of Medicine, Ankara, Turkey
    Urol Int 85:257-60. 2010
    ..We retrospectively review patients who underwent ureteral implantation with a psoas hitch during obstetric or gynecologic operations and describe a new modification...
  31. pmc Iliopsoas abscesses
    I H Mallick
    University Department of Surgery, Royal Free and University College Medical School, Hampstead, London NW3 2QG, UK
    Postgrad Med J 80:459-62. 2004
    ..Its insidious onset and occult characteristics can cause diagnostic delays, resulting in high mortality and morbidity. The epidemiology, aetiology, clinical features, and management of iliopsoas abscess are discussed...
  32. pmc Kinetics of thin filament activation probed by fluorescence of N-((2-(iodoacetoxy)ethyl)-N-methyl)amino-7-nitrobenz-2-oxa-1,3-diazole-labeled troponin I incorporated into skinned fibers of rabbit psoas muscle: implications for regulation of muscle contrac
    B Brenner
    Department of Molecular and Cell Physiology, Medical School Hannover, D 30623 Hannover, Germany
    Biophys J 77:2692-708. 1999
    ....
  33. pmc An asymmetry in the phosphate dependence of tension transients induced by length perturbation in mammalian (rabbit psoas) muscle fibres
    K W Ranatunga
    Department of Physiology, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK
    J Physiol 542:899-910. 2002
    ..The results indicate that the P(i)-sensitive force generation identified in previous studies is strain sensitive (as expected), but it is seen only with respect to positive strain (stretches)...
  34. pmc Presence of enolase in the M-band of skeletal muscle and possible indirect interaction with the cytosolic muscle isoform of creatine kinase
    G Foucault
    Gènes et Protéines Musculaires, EP CNRS 1088, Centre Scientifique d Orsay, France
    Biochem J 338:115-21. 1999
    ..This is the first demonstration of the presence of an enzyme of energy metabolism other than CK at the M-band of myofibres...
  35. ncbi Colocalization of muscle FBPase and muscle aldolase on both sides of the Z-line
    D Rakus
    Department of Animal Physiology, Institute of Zoology, Wroclaw University, Cybulskiego 30, 50 205 Wroclaw, Poland
    Biochem Biophys Res Commun 311:294-9. 2003
    ..The colocalization of FBPase and aldolase on alpha-actinin of the Z-line indicates the existence of glyconeogenic metabolon in vertebrates' myocytes...
  36. ncbi Stretch-induced force enhancement and stability of skeletal muscle myofibrils
    Dilson E Rassier
    Department of Bioengineering, University of Washington, Seattle, WA 98195, USA
    Adv Exp Med Biol 538:501-15; discussion 515. 2003
    ..It is concluded that sarcomeres are stable, and therefore the increased force observed after stretch must be a sarcomeric property, not associated with continuous length changes of unstable sarcomeres, as had been assumed in the past...
  37. ncbi Connecting filament mechanics in the relaxed sarcomere
    Ekaterina Nagornyak
    Department of Bioengineering, University of Washington, 357962, Seattle, WA 98195, USA
    J Muscle Res Cell Motil 26:303-6. 2005
    ..7 nm...
  38. pmc Kinetics of force recovery following length changes in active skinned single fibres from rabbit psoas muscle: analysis and modelling of the late recovery phase
    Kevin Burton
    The Randall Division of Cell and Molecular Biophysics, New Hunt s House, Guy s Campus, King s College London, London SE1 1UL, UK
    J Physiol 573:305-28. 2006
    ....
  39. pmc Dynamic behaviour of half-sarcomeres during and after stretch in activated rabbit psoas myofibrils: sarcomere asymmetry but no 'sarcomere popping'
    I A Telley
    Laboratory for Biomechanics, ETH Zurich, ETH Honggerberg, HCI E 357 1, CH 8093 Zurich, Switzerland
    J Physiol 573:173-85. 2006
    ..In general, the half-sarcomere length changes (dynamics) before and after stretch were slow and the dynamics after stretch were not readily predictable on the basis of the steady-state force-sarcomere length relation...
  40. ncbi Myofibrillar determinants of rate of relaxation in skinned skeletal muscle fibers
    Ye Luo
    Department of Physiology and Cell Biology, Ohio State University, Columbus, OH 43210, USA
    Adv Exp Med Biol 538:573-81; discussion 581-2. 2003
    ....
  41. pmc Contractile effects of the exchange of cardiac troponin for fast skeletal troponin in rabbit psoas single myofibrils
    N Piroddi
    Dipartimento di Scienze Fisiologiche, Universita di Firenze, I 50134 Firenze, Italy
    J Physiol 552:917-31. 2003
    ..70 to 6.44 and reduced the Hill coefficient from 3.3 to 1.4, suggesting that regulatory protein isoforms primarily alter Ca2+ sensitivity and the cooperativity of the force-generating mechanism...
  42. pmc Mechanical properties of single myosin molecules probed with the photonic force microscope
    Tim Scholz
    Medizinische Hochschule Hannover, Molekular und Zellphysiologie, Hannover, Germany
    Biophys J 88:360-71. 2005
    ..This pivot location coincides with myosin's hinge region. We demonstrate the general applicability of thermal fluctuation analysis to determine elastic properties and geometrical factors of individual molecules...
  43. ncbi Effect of sarcomere length on step size in relaxed rabbit psoas muscle
    Ekaterina Nagornyak
    Department of Bioengineering 357962, University of Washington, Seattle, WA 98195, USA
    J Muscle Res Cell Motil 25:37-43. 2004
    ..7 nm...
  44. ncbi Light microscopy and image analysis of thin filament lengths utilizing dual probes on beef, chicken, and rabbit myofibrils
    T P Ringkob
    Department of Animal Biotechnology, University of Nevada, Reno 89557, USA
    J Anim Sci 82:1445-53. 2004
    ..Strips of beef cutaneous trunci, rectus abdominis, psoas, and masseter; chicken pectoralis; and rabbit psoas muscles were excised 5 to 30 min postmortem...
  45. ncbi Why choose myofibrils to study muscle myosin ATPase?
    Corinne Lionne
    UMR 5121, CNRS Université Montpellier I, Institut de Biologie, 4 boulevard Henri IV CS89508, 34960 Montpellier 2, France
    J Muscle Res Cell Motil 24:139-48. 2003
    ..It is concluded that great care should be taken when extrapolating mechanochemical properties of the contractile proteins in solution to the whole muscle...
  46. ncbi Gigantic variety: expression patterns of titin isoforms in striated muscles and consequences for myofibrillar passive stiffness
    Ciprian Neagoe
    Institute of Physiology and Pathophysiology, University of Heidelberg, Im Neuenheimer Feld 326, D 69120 Heidelberg, Germany
    J Muscle Res Cell Motil 24:175-89. 2003
    ....
  47. ncbi Evidence for the involvement of myosin subfragment 2 in muscle contraction
    Haruo Sugi
    Department of Physiology, School of Medicine, Teikyo University, Itabashi ku, Tokyo 173 0003, Japan
    Adv Exp Med Biol 538:317-31; discussion 331-2. 2003
  48. ncbi Dynamic structures of motor proteins myosin and kinesin, and switch protein troponin as detected by SDSL-ESR
    Toshiaki Arata
    Department of Biology, Graduate School of Science, Osaka University, 1 1 Machikeneyama cho, Toyonaka 560 0043, Japan
    J Electron Microsc (Tokyo) 54:i47-51. 2005
    ..We also succeeded in fixing the newly-synthesized bifunctional spin label rigidly on the TnC molecule in solution, indicating that we can determine the precise coordinate of the spin principal axis of troponin on the oriented filament...
  49. ncbi Lower active force generation and improved fatigue resistance in skeletal muscle from desmin deficient mice
    J Balogh
    Department of Physiological Sciences, Lund University, BMC F11, Tornavagen 10, SE 221 84, Lund, Sweden
    J Muscle Res Cell Motil 24:453-9. 2003
    ..Previous studies have reported a switch towards slower myosin isoforms in slow skeletal muscle of Des-/- mice. The increased fatigue resistance show that this change is reflected in the physiological function of the muscle...
  50. ncbi Does phosphate release limit the ATPases of soleus myofibrils? Evidence that (A)M. ADP.Pi states predominate on the cross-bridge cycle
    Bogdan Iorga
    UMR 5121, Universite Montpellier, Montpellier, France
    J Muscle Res Cell Motil 25:367-78. 2004
    ..ADP.Pi. We propose a reaction pathway that includes several (A)M.ADP.Pi sub-states that are either 'weak' or 'strong', depending on the mechanical condition...
  51. ncbi Correlation between mechanical and enzymatic events in contracting skeletal muscle fiber
    A Shepard
    Department of Molecular Biology and Immunology, University of North Texas, 3500 Camp Bowie Boulevard, Fort Worth, Texas 7610, USA
    Biochemistry 43:2804-11. 2004
    ..Such sequence of events was indeed observed in contracting muscle fibers, suggesting that mechanical and enzymatic events are tightly coupled in vivo...
  52. pmc Strong binding of myosin heads stretches and twists the actin helix
    Andrey K Tsaturyan
    Institute of Mechanics, M V Lomonosov Moscow State University, Moscow, Russia
    Biophys J 88:1902-10. 2005
    ..Our measurement of actin compliance obtained by applying tension to fibers in rigor is consistent with the results of mechanical measurements...
  53. ncbi Mutations of hydrophobic residues in the N-terminal domain of troponin C affect calcium binding and exchange with the troponin C-troponin I96-148 complex and muscle force production
    Jonathan P Davis
    Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio 43210, USA
    J Biol Chem 279:17348-60. 2004
    ..In conclusion, elucidating the determinants of calcium binding and exchange with troponin C in the presence of troponin I provides a deeper understanding of how troponin C controls signal transduction...
  54. ncbi Misplacement of a psoas compartment catheter in the subarachnoid space
    Rainer J Litz
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Dresden, Germany
    Reg Anesth Pain Med 29:60-4. 2004
    ..This case report describes an unusual cause of misplacement of an indwelling catheter in the subarachnoid space after primary psoas compartment block in a patient undergoing total knee arthroplasty...
  55. ncbi Molecular organizations of myofibrils of skeletal muscle studied by atomic force microscopy
    Takenori Yamada
    Department of Physics Biophysics Section, Faculty of Science, Science University of Tokyo, Shinjuku ku, Tokyo 162 8601, Japan
    Adv Exp Med Biol 538:285-94; discussion 294. 2003
    ..In any case the present studies clearly indicate that the AFM technique is a powerful tool to investigate the mechanical characteristics of sarcomere structure of muscle fiber...
  56. pmc Sarcomere popping requires stretch over a range where total tension decreases with length
    David L Morgan
    J Physiol 574:627-8; author reply 629-30. 2006
  57. ncbi Evidence that phosphate release is the rate-limiting step on the overall ATPase of psoas myofibrils prevented from shortening by chemical cross-linking
    Corinne Lionne
    INSERM U128, 1919 Route de Mende, 34293 Montpellier Cedex 5, France
    Biochemistry 41:13297-308. 2002
    ..ADP state. We discuss two models for accommodating the mechanical and chemical kinetics with reference to the duty cycle in skeletal muscle...
  58. pmc Titin-based contribution to shortening velocity of rabbit skeletal myofibrils
    Ave Minajeva
    Institute of Physiology and Pathophysiology, University of Heidelberg, Im Neuenheimer Feld 326, D 69120 Heidelberg, Germany
    J Physiol 540:177-88. 2002
    ..However, elastic recoil may aid active shortening during phases of high elastic energy utilization, i.e. immediately after the onset of contraction under low or zero load or during prolonged shortening from greater physiological SLs...
  59. ncbi Rapid cryofixation of rabbit muscle fibres after a temperature jump
    P M Bennett
    The Randall Centre for Molecular Mechanisms of Cell Function, Guy s, King s and St Thomas School of Biomedical Sciences, King s College London, New Hunts House, Guys Campus, London SE1 1UL, UK
    J Microsc 206:152-60. 2002
    ..We conclude that we have preserved the 'hot' structure and that cryofixation is sufficiently fast to prevent the transition back to the 'cold' state...
  60. ncbi Fluorescence changes on contractile activation in TnC(DANZ) labeled skinned rabbit psoas fibers
    M Huang
    Department of Biomedical Engineering, Columbia University, New York, NY 10032, USA
    J Muscle Res Cell Motil 22:635-46. 2001
    ..There is evidence that, in the overlap zone, weakly attached myosin cross-bridges enhance cooperation between the regulatory units of the thin filaments...
  61. ncbi Effect of nucleotides and their analogues on essential light chains in myosin head
    Nóra Hartvig
    Central Research Laboratory, Faculty of Medicine, University of Pecs, 12 Szigeti Str, H 7643 Pecs, Hungary
    J Biochem Biophys Methods 53:67-74. 2002
    ..In the presence of ADP and orthovanadate the intensity of the spectra decreased, which showed the dissociation of S1 and this was accompanied with the disappearance of the orientation dependence...
  62. ncbi The length of cooperative units on the thin filament in rabbit psoas muscle fibres
    Wei Ding
    Department of Anatomy and Cell Biology, The University of Iowa, Iowa City, IA 52242, USA
    Exp Physiol 87:691-7. 2002
    ..We infer from the second observation that the Ca(2+) sensitivity is slightly reduced by removal of the cooperative interaction between neighbouring cooperative units...
  63. ncbi Measurement of muscle fiber stiffness during stretch with two continuous different velocities in skeletal muscle fibers
    Takakazu Kobayashi
    Department of Electronic Engineering, Shibaura Institute of Technology, Tokyo, 135 8548 Japan
    Conf Proc IEEE Eng Med Biol Soc 2007:5811-4. 2007
    ..5% with a velocity, and then it was further stretched by 1.5% with another velocity. It is suggested that, during stretch, a considerable fraction of cross-bridges slow down their cycling rate and increase their force-generating ability...
  64. ncbi High mechanical efficiency of the cross-bridge powerstroke in skeletal muscle
    Haruo Sugi
    Department of Physiology, School of Medicine, Teikyo University, Itabashi ku, Tokyo 173 8605, Japan
    J Exp Biol 206:1201-6. 2003
    ..A conservative estimation of the maximum mechanical efficiency at a load of 0.5-0.6 P(o) was 0.7, suggesting that the actual maximum mechanical efficiency of cross-bridge powerstrokes may be close to unity...
  65. pmc Thin filament activation and unloaded shortening velocity of rabbit skinned muscle fibres
    Carl A Morris
    Department of Physiology, School of Medicine, University of California, Los Angeles, CA 90095, USA
    J Physiol 550:205-15. 2003
    ....
  66. ncbi Functional effects of the DCM mutant Gly159Asp troponin C in skinned muscle fibres
    Laura C Preston
    Department of Physiology, University of Oxford, Oxford, UK
    Pflugers Arch 453:771-6. 2007
    ..In vivo, this mutation may cause both a slowing of force generation and reduction in total systolic force. This represents a novel mechanism by which a cardiomyopathy-causing mutation can affect contractility...
  67. ncbi Passive force enhancement in single myofibrils
    V Joumaa
    Human Performance Laboratory, University of Calgary, Calgary, Canada
    Pflugers Arch 455:367-71. 2007
    ..We propose that this might occur through an increase in stiffness when calcium concentration increases upon activation...
  68. pmc Differential scanning calorimetry study of glycerinated rabbit psoas muscle fibres in intermediate state of ATP hydrolysis
    Timea Dergez
    Institute of Bioanalysis Faculty of Medicine, H 7624 Pecs, Hungary
    BMC Struct Biol 7:41. 2007
    ..The energetics of long functioning intermediate states of ATP hydrolysis cycle was studied in muscle fibres by differential scanning calorimetry (DSC)...
  69. pmc Faster force transient kinetics at submaximal Ca2+ activation of skinned psoas fibers from rabbit
    D A Martyn
    Center for Bioengineering, University of Washington, Seattle 98195
    Biophys J 68:235-42. 1995
    ..The data are consistent with models that incorporate a direct effect of [Ca2+] on phase 2 kinetics of individual cross-bridges or, alternatively, in which phase 2 kinetics depend on cooperative interactions between cross-bridges...
  70. ncbi The origin of passive force enhancement in skeletal muscle
    V Joumaa
    Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada
    Am J Physiol Cell Physiol 294:C74-8. 2008
    ..The findings of the present study suggest that passive force enhancement is partly caused by a calcium-induced increase in titin stiffness but also requires cross-bridge formation and/or active force production for full manifestation...
  71. pmc A novel mutant cardiac troponin C disrupts molecular motions critical for calcium binding affinity and cardiomyocyte contractility
    Chee Chew Lim
    Department of Cardiovascular Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Biophys J 94:3577-89. 2008
    ..This in turn may trigger pathways leading to aberrant ventricular remodeling and ultimately a dilated cardiomyopathy phenotype...
  72. pmc Regulation of force development studied by photolysis of caged ADP in rabbit skinned psoas fibers
    Z Lu
    Department of Physiology, University of Wisconsin, Madison, Wisconsin 53706, USA
    Biophys J 81:334-44. 2001
    ..This cooperative interaction influences both the magnitude and kinetics of force generation in skeletal muscle...
  73. ncbi Evidence for high mechanical efficiency of cross-bridge powerstroke in skeletal muscle
    Haruo Sugi
    Department of Physiology, School of Medicine, Teikyo University, Itabashi ku, Tokyo 173 0003, Japan
    Adv Exp Med Biol 538:603-11; discussion 612. 2003
  74. pmc Orientational changes of crossbridges during single turnover of ATP
    J Borejdo
    Department of Molecular Biology and Immunology, University of North Texas, Fort Worth, Texas 76107 2699, USA
    Biophys J 84:2450-9. 2003
    ..A model was constructed that quantified this effect. After accounting for the slowdown, the halftimes of dissociation and attachment were 34 and 200 ms, respectively...
  75. ncbi Thymol: a classical small-molecule compound that has a dual effect (potentiating and inhibitory) on myosin
    Takumi Tamura
    Structural Biochemistry Laboratory, RIKEN Harima Institute, SPring 8, Hyogo 679 5148, Japan
    Biochem Biophys Res Commun 318:786-91. 2004
    ..Thymol may serve as a potent tool for studying the mechanism of coupling between the ATPase reaction and contraction in muscle...
  76. ncbi Force enhancement by PEG during ramp stretches of skeletal muscle
    Marc Chinn
    Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143, USA
    J Muscle Res Cell Motil 24:571-8. 2003
    ....
  77. pmc Effects of sarcomere length and temperature on the rate of ATP utilisation by rabbit psoas muscle fibres
    K Hilber
    School of Biomedical Sciences, King's College London, New Hunt's House, Guy's Campus, London SE1 1UL, UK
    J Physiol 531:771-80. 2001
    ..6. Application of the NADH-linked assay to single muscle fibres in oil improves the effective sensitivity and time resolution of the method, and allows continuous measurements of the rate of ADP production during active contraction...
  78. ncbi Helical order in myosin filaments and evidence for one ligand inducing multiple myosin conformations
    Leepo C Yu
    Laboratory of Muscle Biology, NIAMS, NIH, Bethesda, MD 20892, USA
    Adv Exp Med Biol 538:305-16. 2003
  79. ncbi Actin sliding on reconstituted myosin filaments containing only one myosin heavy chain isoform
    Tim Scholz
    Medizinische Hochschule Hannover, Molekular und Zellphysiologie, Carl Neuberg Str 1, 30625 Hannover, Germany
    J Muscle Res Cell Motil 24:77-86. 2003
    ..1999) J Muscle Res Cell Motil 20(8): 785-796)...
  80. pmc Structural characterization of weakly attached cross-bridges in the A*M*ATP state in permeabilized rabbit psoas muscle
    S Xu
    National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biophys J 82:2111-22. 2002
    ..The significance of the flexibility in the A*M*ATP complex in the process of force generation is discussed...
  81. pmc A model of cross-bridge attachment to actin in the A*M*ATP state based on x-ray diffraction from permeabilized rabbit psoas muscle
    Jin Gu
    National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biophys J 82:2123-33. 2002
    ....
  82. ncbi Analysis of nucleotide myosin complexes in skeletal muscle fibres by DSC and EPR
    D Lorinczy
    Biophysical Department, Faculty of Medicine, University of Pecs, H 7624, Pecs, 12 Szigeti Str, Hungary
    J Biochem Biophys Methods 53:75-87. 2002
    ..Saturation transfer EPR measurements reported increased rotational mobility of spin labels in the presence of ATP plus phosphate analogues corresponding to weakly binding state of myosin to actin...
  83. pmc Structural characterization of the binding of Myosin*ADP*Pi to actin in permeabilized rabbit psoas muscle
    Sengen Xu
    National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Biophys J 91:3370-82. 2006
    ....
  84. ncbi [The use of botulinum toxin in the treatment of spastic hip joint instability in children with cerebral palsy]
    Marek Jozwiak
    Katedra i Klinika Ortopedii i Traumatologii Dzieciecej, Uniwersytet Medyczny im Karola Marcinkowskiego w Poznaniu
    Chir Narzadow Ruchu Ortop Pol 72:205-9. 2007
    ..Authors present the effect of intramuscular injections of botulinum toxin A (BTX-A) in the treatment of hip instability in children with spastic cerebral palsy...
  85. ncbi Margin-free spondylectomy for extended malignant spine tumors: surgical technique and outcome of 13 cases
    Kazuhiro Hasegawa
    Niigata Spine Surgery Center, Niigata City, Niigata, Japan
    Spine (Phila Pa 1976) 32:142-8. 2007
    ..Description of surgical technique and retrospective review of 13 cases...
  86. ncbi Effect of position and alteration in synergist muscle force contribution on hip forces when performing hip strengthening exercises
    CARA L LEWIS
    Human Neuromechanics Laboratory, Division of Kinesiology, University of Michigan, 401 Washtenaw Avenue, Ann Arbor, MI 48109 2214, USA
    Clin Biomech (Bristol, Avon) 24:35-42. 2009
    ..The purpose of this study was to evaluate hip joint forces created across a range of hip flexion and extension angles during two hip strengthening exercises: prone hip extension and supine hip flexion...
  87. ncbi Peripheral primitive neuroectodermal tumor (PPNET) of pelvic origin: report of a case arising from an unusual location
    Vito D'Andrea
    Department of Surgical Sciences, Division of General Surgery, La Sapienza University, Rome, Italy
    Tumori 89:202-6. 2003
    ..oblique left inguinal incision to remove the neoplasm, which consisted of a large mass surrounding the iliac-psoas muscles, extending from the transverse apophysis of the spinal column to Scarpa's triangle, and passing through the ..
  88. ncbi Psoas abscesses caused by Paracoccidioides brasiliensis in an adolescent
    Mariana Tresoldi Neves
    Department of Pediatrics, Faculty of Medical Science, University of Campinas, Campinas, Brazil
    Mycopathologia 167:89-93. 2009
    ..In order to describe the case of an adolescent who developed psoas abscesses caused by Paracoccidiodes brasiliensis...
  89. pmc Mechanical study of rat soleus muscle using caged ATP and X-ray diffraction: high ADP affinity of slow cross-bridges
    K Horiuti
    Department of Physiology, Oita Medical University, Japan
    J Physiol 502:433-47. 1997
    1. The cross-bridges in slow- and fast-twitch fibres (taken, respectively, from soleus and psoas muscles of rats) were examined in mechanical experiments using caged ATP and X-ray diffraction, to compare their binding of ATP and ADP. 2...
  90. ncbi Body composition analysis of the pig by magnetic resonance imaging
    A D Mitchell
    USDA ARS, Beltsville, MD 20705, USA
    J Anim Sci 79:1800-13. 2001
    ..MRI volume measurements of fat and muscle regions (Jowl fat, backfat, shoulder muscles, LD muscles, psoas muscles, ham muscles, a 10-cm section of the longissimus muscles and overlying fat, and a 15-cm section of the ham ..
  91. ncbi Effect of paratropomyosin on the increase in sarcomere length of rigor-shortened skeletal muscles
    M Yamanoue
    Department of Animal Science, Faculty of Agriculture, Hokkaido University
    J Biochem 103:843-7. 1988
    ..Using glycerinated fibers of rabbit psoas muscles, we studied the effect of paratropomyosin on the weakening of rigor linkages, which was followed in terms of ..
  92. ncbi Biomechanical and morphologic evaluation of a three-dimensional fabric sheep artificial intervertebral disc: in vitro and in vivo analysis
    K Kadoya
    Department of Orthopaedic Surgery, Hokkaido University, Graduate School of Medicine, Sapporo, Japan
    Spine (Phila Pa 1976) 26:1562-9. 2001
    ..For in vivo evaluation after placing in the sheep psoas muscles for 6 months, the surface of the three-dimensional fabric disc was evaluated using macroscopy and scanning ..
  93. ncbi Salmonella osteomyelitis of multiple ribs and thoracic vertebra with large psoas muscle abscesses
    Xiujun Zheng
    Department of Spine Surgery, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, P R China
    Spine J 9:e1-4. 2009
    ..Salmonella vertebral osteomyelitis is a well-known complication of sickle cell disease. However, it has been infrequently reported in immunologically normal people or diabetic patients...
  94. ncbi Pathologic findings in malignant hyperthermia: a case report and review of literature
    Lydia R Christiansen
    Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Forensic Med Pathol 25:327-33. 2004
    ..At autopsy, the abdomen contained 1800 mL of blood, and bilateral hematomas were present in the psoas muscles. The authors present this case of clinically apparent malignant hyperthermia, discuss how to approach such a ..
  95. ncbi Dorsolumbar junction spinal tuberculosis in an infant: case report
    Kadir Tufan
    Department of Neurosurgery, Gazi University Medical School, Ankara, Turkey
    J Neurosurg 102:431-5. 2005
    ..demonstrated destruction by a tuberculous abscess of the T-12 and L-1 vertebral bodies, extending into the psoas muscles and spinal canal...
  96. ncbi Vertebral body hyperostosis as a presentation of Pott's disease: a report of two cases and literature review
    Alok Umredkar
    Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Neurol India 58:125-7. 2010
    ..had associated lupus vulgaris, while the second patient had milliary mottling of lungs and calcified bilateral psoas muscles. Surgical decompression, followed by full-dose chemotherapy, remains the hallmark of management of this disease...
  97. ncbi Recurrent hernia following endoscopic total extraperitoneal repair
    Pradeep K Chowbey
    Department of Minimal Access Surgery, Sir Ganga Ram Hospital, New Delhi, India
    J Laparoendosc Adv Surg Tech A 13:21-5. 2003
    ..A retrospective study was conducted to identify the reasons for recurrence following endoscopic total extraperitoneal (TEP) repair of inguinal hernias and to develop a strategy to prevent recurrence...
  98. pmc Protein kinase A-dependent modulation of Ca2+ sensitivity in cardiac and fast skeletal muscles after reconstitution with cardiac troponin
    Douchi Matsuba
    Department of Cell Physiology, Jikei University School of Medicine, Tokyo 105 8461, Japan
    J Gen Physiol 133:571-81. 2009
    ..It is therefore suggested that the PKA-dependent phosphorylation or dephosphorylation of cTnI universally modulates Ca2+ sensitivity associated with cTnC in the striated muscle sarcomere, independent of the TnT isoform...
  99. ncbi Evaluation of a deformable musculoskeletal model for estimating muscle-tendon lengths during crouch gait
    A S Arnold
    Mechanical Engineering Department, Stanford University, CA 94305 3030, USA
    Ann Biomed Eng 29:263-74. 2001
    The hamstrings and psoas muscles are often lengthened surgically in an attempt to correct crouch gait in persons with cerebral palsy...
  100. ncbi Changes in lumbar muscle activity because of induced muscle pain evaluated by muscle functional magnetic resonance imaging
    Nele Dickx
    Department of Rehabilitation Sciences and Physical Therapy, Faculty of Medicine, Ghent University, Gent, Belgium
    Spine (Phila Pa 1976) 33:E983-9. 2008
    ..Experimental study of changes in muscle recruitment during trunk extension exercise at 40% of the repetition maximum, because of induced muscle pain...
  101. ncbi MRI study of the size, symmetry and function of the trunk muscles among elite cricketers with and without low back pain
    J Hides
    Division of Physiotherapy, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia
    Br J Sports Med 42:809-13. 2008
    ..To determine if asymmetry of trunk muscles and deficits of motor control exist among elite cricketers with and without low back pain (LBP)...

Research Grants16

  1. Calorimetry Work Station
    SHERWIN LEHRER; Fiscal Year: 2002
    ..iii) measure binding constants and characterize the thermodynamics of binding equilibria. ITC avoids the unavoidable perturbation of fluorescence labels and is more quantitatively than ELISA assays of binding. ..
  2. TROPOMYOSIN AND THE REGULATION OF MUSCLE CONTRACTION
    SHERWIN LEHRER; Fiscal Year: 2009
    ..These measurements between specific labeled amino acid residues will provide information about the dynamics of the changes between the components involved in the regulatory process. ..
  3. DO LIGHT CHAIN EXTENSIONS ENHANCE MUSCLE POWER OUTPUT?
    David Maughan; Fiscal Year: 2004
    ..This research will contribute to understanding and treating human muscle diseases in which power output is compromised. ..
  4. RESEARCH TRAINING IN PHYSIOLOGICAL ADAPTATION TO STRESS
    Leonard Jefferson; Fiscal Year: 2005
    ..abstract_text> ..
  5. Alcohol-Induced Regulation of Hepatic Protein Synthesis
    THOMAS VARY; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  6. Spectroscopy of myosin light chain domain dynamics
    Osha Roopnarine; Fiscal Year: 2010
    ....
  7. Myocardial Stiffness in Aging Associated Diastolic Heart Failure
    Kenneth Campbell; Fiscal Year: 2007
    ..The experimental results will provide new information about the underlying causes of DHF and should help scientists develop better treatments for diastolic dysfunction in elderly populations. [unreadable] [unreadable] [unreadable]..
  8. Rotation of Single Cross-Bridge in Skeletal Muscle Fiber
    Julian Borejdo; Fiscal Year: 2007
    ..This is expected to provide definitive answers about the mechanism of contraction of skeletal muscle. ..
  9. Effects of Myostatin Deficiency on Bone Strength
    Mark Hamrick; Fiscal Year: 2007
    ..abstract_text> ..
  10. Improved Confocal Microscope: Detection & Functionality
    Julian Borejdo; Fiscal Year: 2005
    ..To facilitate a future commercialization, a microscope maintenance/modification company that is interested in distribution of the product version of the modification package has been identified. ..
  11. MOLECULAR BASIS OF DIABETIC CARDIOMYOPATHY
    David Maughan; Fiscal Year: 2003
    ..This research will contribute to understanding and treating human myocardial pathologies that arise from diabetes mellitus, with particular attention to diastolic dysfunctions. (End of Abstract) ..
  12. IMAGING MELANIN IN MELANOCYTES
    Julian Borejdo; Fiscal Year: 2003
    ..The modifications are relatively simple, inexpensive and not tied to a specific brand of instrument. It is expected that the method will find application in a small diagnostic laboratory. ..
  13. MUSCLE RESPONSE TO STRESS IN CANINE MUSCULAR DYSTROPHY
    MARTIN CHILDERS; Fiscal Year: 2002
    ..It is anticipated that findings will improve the understanding of how dystrophic muscle responds to physical stress resulting in improved treatment for patients with Duchenne muscular dystrophy. ..
  14. Myosin-based kinetic differences between muscle types
    David Maughan; Fiscal Year: 2006
    ..abstract_text> ..
  15. Leupeptin in a Canine Model of Duchenne Muscular Dystrophy
    MARTIN CHILDERS; Fiscal Year: 2006
    ..Specific Aim #4b: Compare lean body muscle mass and calpain activity between leupeptin and placebo-treated GRMD dogs. ..
  16. CARDIAC CONTRACTILE KINETICS
    Michael Regnier; Fiscal Year: 2009
    ..abstract_text> ..