heart septum

Summary

Summary: The thin membranous structure between the two heart atria or the thick muscular structure between the two heart ventricles.

Top Publications

  1. ncbi Septal ethanol ablation for hypertrophic obstructive cardiomyopathy: early and intermediate results of a Canadian referral centre
    Rohan Bhagwandeen
    Toronto General Hospital, Toronto, Canada
    Can J Cardiol 19:912-7. 2003
  2. ncbi Tbx5 specifies the left/right ventricles and ventricular septum position during cardiogenesis
    Jun K Takeuchi
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5, Takayama, Ikoma, Nara 630 0101, Japan
    Development 130:5953-64. 2003
  3. ncbi Temporal and distinct TGFbeta ligand requirements during mouse and avian endocardial cushion morphogenesis
    Todd D Camenisch
    Department of Biochemistry and Molecular Biology, Mayo Clinic, Scottsdale, AZ 85259, USA
    Dev Biol 248:170-81. 2002
  4. ncbi Versican expression is associated with chamber specification, septation, and valvulogenesis in the developing mouse heart
    D J Henderson
    Neural Development Unit, Institute of Child Health, University College London, UK
    Circ Res 83:523-32. 1998
  5. ncbi Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart
    Diego Franco
    Department of Experimental Biology, Faculty of Experimental Sciences, University of Jaen, 23071 Jaen, Spain
    Dev Biol 294:366-75. 2006
  6. ncbi Controversies in cardiovascular medicine. Benefits of surgery in obstructive hypertrophic cardiomyopathy: bring septal myectomy back for European patients
    Barry J Maron
    Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 E 28th Street, Minneapolis, MN 55407, USA
    Eur Heart J 32:1055-8. 2011
  7. ncbi Surgical septal myectomy decreases the risk for appropriate implantable cardioverter defibrillator discharge in obstructive hypertrophic cardiomyopathy
    Christopher J McLeod
    Department of Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Eur Heart J 28:2583-8. 2007
  8. doi Myths about surgical myectomy: rumors of its death have been greatly exaggerated
    Barry J Maron
    Am J Cardiol 101:887-9. 2008
  9. ncbi Controversies in cardiovascular medicine. Hypertrophic obstructive cardiomyopathy: alcohol septal ablation
    Michael A Fifer
    Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Eur Heart J 32:1059-64. 2011
  10. ncbi Prevalence of idiopathic hypertrophic cardiomyopathy in China: a population-based echocardiographic analysis of 8080 adults
    Yubao Zou
    Sino German Laboratory for Molecular Medicine, Beijing, China
    Am J Med 116:14-8. 2004

Detail Information

Publications214 found, 100 shown here

  1. ncbi Septal ethanol ablation for hypertrophic obstructive cardiomyopathy: early and intermediate results of a Canadian referral centre
    Rohan Bhagwandeen
    Toronto General Hospital, Toronto, Canada
    Can J Cardiol 19:912-7. 2003
    ..This procedure involves targeted infarction of the basal interventricular septum to reduce left ventricular outflow tract (LVOT) obstruction...
  2. ncbi Tbx5 specifies the left/right ventricles and ventricular septum position during cardiogenesis
    Jun K Takeuchi
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5, Takayama, Ikoma, Nara 630 0101, Japan
    Development 130:5953-64. 2003
    ..Taken together, our data indicate that Tbx5 specifies the identity of LV through tight interactions among several heart-specific factors, and highlight the essential roles of Tbx5 in cardiac development...
  3. ncbi Temporal and distinct TGFbeta ligand requirements during mouse and avian endocardial cushion morphogenesis
    Todd D Camenisch
    Department of Biochemistry and Molecular Biology, Mayo Clinic, Scottsdale, AZ 85259, USA
    Dev Biol 248:170-81. 2002
    ..Thus, both TGFbeta2 and TGFbeta3 appear necessary for the full morphogenetic program of EMT in the chick, but only TGFbeta2 is expressed and obligatory for mammalian endocardial cushion cell transformation...
  4. ncbi Versican expression is associated with chamber specification, septation, and valvulogenesis in the developing mouse heart
    D J Henderson
    Neural Development Unit, Institute of Child Health, University College London, UK
    Circ Res 83:523-32. 1998
    ..Versican may be a key participant in cardiogenesis, responding to the many diffusible signals that mediate interactions between the developing endocardium and myocardium...
  5. ncbi Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart
    Diego Franco
    Department of Experimental Biology, Faculty of Experimental Sciences, University of Jaen, 23071 Jaen, Spain
    Dev Biol 294:366-75. 2006
    ..Examination of the orientation as well as the distribution of labeled cells in clusters provides new insights into the morphogenesis of the septum...
  6. ncbi Controversies in cardiovascular medicine. Benefits of surgery in obstructive hypertrophic cardiomyopathy: bring septal myectomy back for European patients
    Barry J Maron
    Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 E 28th Street, Minneapolis, MN 55407, USA
    Eur Heart J 32:1055-8. 2011
    ..It is our aspiration that this discussion will generate reconsideration and resurgence of interest in surgical septal myectomy as a treatment option for severely symptomatic obstructive HCM patients within Europe...
  7. ncbi Surgical septal myectomy decreases the risk for appropriate implantable cardioverter defibrillator discharge in obstructive hypertrophic cardiomyopathy
    Christopher J McLeod
    Department of Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Eur Heart J 28:2583-8. 2007
    ..Surgical myectomy is the primary treatment strategy for relief of symptoms owing to LVOTO and has been hypothesized to decrease the potential for ventricular tachyarrhythmias...
  8. doi Myths about surgical myectomy: rumors of its death have been greatly exaggerated
    Barry J Maron
    Am J Cardiol 101:887-9. 2008
  9. ncbi Controversies in cardiovascular medicine. Hypertrophic obstructive cardiomyopathy: alcohol septal ablation
    Michael A Fifer
    Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Eur Heart J 32:1059-64. 2011
    ..Non-randomized comparisons of septal ablation and septal myectomy have shown similar mortality rates and post-procedure New York Heart Association class for the two procedures...
  10. ncbi Prevalence of idiopathic hypertrophic cardiomyopathy in China: a population-based echocardiographic analysis of 8080 adults
    Yubao Zou
    Sino German Laboratory for Molecular Medicine, Beijing, China
    Am J Med 116:14-8. 2004
    ..To determine the prevalence of hypertrophic cardiomyopathy in China...
  11. ncbi American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European S
    Barry J Maron
    J Am Coll Cardiol 42:1687-713. 2003
  12. ncbi Septal dyskinesia and global left ventricular dysfunction in pediatric Wolff-Parkinson-White syndrome with septal accessory pathway
    Bo Sang Kwon
    Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
    J Cardiovasc Electrophysiol 21:290-5. 2010
    ..The aim of the present study was to determine the extent to which the AP contributes to global left ventricular (LV) dysfunction...
  13. ncbi Dynamic left ventricular outflow tract obstruction secondary to catecholamine excess in a normal ventricle
    S Mingo
    Int J Cardiol 112:393-6. 2006
    ..We have met only one case reported in the literature matching those conditions. In order to treat this type of patients properly, it is essential to take in consideration this pathology...
  14. ncbi Role of septal to posterior wall motion delay in cardiac resynchronization therapy
    Maria Vittoria Pitzalis
    J Am Coll Cardiol 48:596-7. 2006
  15. ncbi Mitral valve abnormalities in hypertrophic cardiomyopathy: echocardiographic features and surgical outcomes
    Ryan K Kaple
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    Ann Thorac Surg 85:1527-35, 1535.e1-2. 2008
    ..This study was conducted to define the echocardiographic features of MV pathology in patients with HCM and relate these to repairability of the MV, MV procedures performed, durability of repair, and survival...
  16. ncbi Surgical management of obstructive hypertrophic cardiomyopathy: the gold standard
    Morgan L Brown
    Division of Cardiovascular Surgery, 200 1st St SW, Rochester, MN 55905, USA
    Expert Rev Cardiovasc Ther 6:715-22. 2008
    ..In our practice, septal myectomy remains the gold standard for treatment of obstructive hypertrophic cardiomyopathy...
  17. ncbi [Evolution of the surgical strategy in hypertrophic cardiomyopathy: case studies of eight patients]
    Thomas Joudinaud
    Service de chirurgie cardiaque, Hopital Bichat, 46, rue Henri Huchard, 75018 Paris, France
    Ann Cardiol Angeiol (Paris) 57:16-21. 2008
    ..There was an evolution in the surgical strategy to treat the patients who present a left ventricular outflow tract gradient...
  18. ncbi Impact of septal myectomy on left atrial volume and left ventricular diastolic filling patterns: an echocardiographic study of young patients with obstructive hypertrophic cardiomyopathy
    Shaji C Menon
    Departments of Pediatric and Adolescent Medicine, Division of Pediatric Cardiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Am Soc Echocardiogr 21:684-8. 2008
    ..Left atrial (LA) enlargement has been associated with exercise intolerance, severity of mitral regurgitation (MR), and left ventricular (LV) outflow tract (LVOT) obstruction in adults with HCM...
  19. ncbi Extended myectomy for hypertrophic obstructive cardiomyopathy after failure or contraindication of septal ablation or with combined surgical procedures
    H Dorge
    Thoracic Cardiovascular Surgery, Heart Center Göttingen, Georg August University Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Thorac Cardiovasc Surg 52:344-8. 2004
    ..The introduction of catheter-based procedures restricts surgical therapy to a subset of patients not suitable for septal ablation or requiring concomitant cardiac surgery...
  20. ncbi Implantable cardioverter-defibrillator therapy for primary prevention of sudden death after alcohol septal ablation of hypertrophic cardiomyopathy
    Frank A Cuoco
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Am Coll Cardiol 52:1718-23. 2008
    ....
  21. ncbi Early onset and progression of left ventricular remodeling after alcohol septal ablation in hypertrophic obstructive cardiomyopathy
    Willem G van Dockum
    Department of Cardiology, VU University Medical Center, Amsterdam, The Netherlands
    Circulation 111:2503-8. 2005
    ..We sought to describe the early to midterm changes and modulating factors of the remodeling process using cardiac MRI (CMR)...
  22. ncbi Ventricular septal rupture after acute myocardial infarction
    Yochai Birnbaum
    Division of Cardiology, University of Texas Medical Branch, Galveston, TX 77555 0553, USA
    N Engl J Med 347:1426-32. 2002
  23. ncbi Interventricular septal configuration at mr imaging and pulmonary arterial pressure in pulmonary hypertension
    Roald J Roeleveld
    Departments of Pulmonology and Physics and Medical Technology, VU University Medical Center Institute of Cardiovascular Research ICaR VU, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    Radiology 234:710-7. 2005
    ..To investigate whether a relationship exists between septum shape and systolic pulmonary arterial pressure (PAP) in patients with pulmonary hypertension...
  24. ncbi Long-term effects of surgical septal myectomy on survival in patients with obstructive hypertrophic cardiomyopathy
    Steve R Ommen
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Am Coll Cardiol 46:470-6. 2005
    ..This study sought to determine the impact of surgical myectomy on long-term survival in hypertrophic cardiomyopathy (HCM)...
  25. ncbi Cardiac septation: a late contribution of the embryonic primary myocardium to heart morphogenesis
    Wouter H Lamers
    Department of Anatomy and Embryology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Circ Res 91:93-103. 2002
    ....
  26. ncbi Comparison of surgical septal myectomy and alcohol septal ablation with cardiac magnetic resonance imaging in patients with hypertrophic obstructive cardiomyopathy
    Uma S Valeti
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
    J Am Coll Cardiol 49:350-7. 2007
    ..This study sought to describe the acute morphologic differences that result from septal myectomy and alcohol septal ablation using cardiac magnetic resonance (CMR) imaging...
  27. ncbi Controversies in cardiovascular medicine. Surgical myectomy remains the primary treatment option for severely symptomatic patients with obstructive hypertrophic cardiomyopathy
    Barry J Maron
    Minneapolis Heart Institute Foundation, 920 E 28th St, Ste 60, Minneapolis, MN 55407, USA
    Circulation 116:196-206; discussion 206. 2007
  28. pmc Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2
    Yasuhiko Sakata
    Vascular Medicine Research, Brigham and Women s Hospital and Harvard Medical School, Cambridge, MA 02139, USA
    Proc Natl Acad Sci U S A 99:16197-202. 2002
    ..These mice provide a useful model for the study of the ontogeny and natural history of ventricular septal defects and cardiomyopathy...
  29. ncbi The effect of dobutamine stress on left ventricular outflow tract gradients in hypertensive patients with basal septal hypertrophy
    Fatih Yalcin
    Baskent University School of Medicine, Department of Cardiology, Medical and Research Center, Adana, Turkey
    Angiology 55:295-301. 2004
    ..This suggests dynamic ventricular ejection by stress may contribute to hypertrophy of the basal segment, which is the closest part of septum to increased afterload...
  30. ncbi Initial experience using a radiofrequency powered transseptal needle
    Matthew P Smelley
    Section of Cardiology, Department of Internal Medicine, University of Chicago, Chicago, Illinois, USA
    J Cardiovasc Electrophysiol 21:423-7. 2010
    ..The purpose of this study was to determine the safety and efficacy of using a novel radiofrequency (RF) powered transseptal needle to perform transseptal puncture (TSP)...
  31. ncbi Transseptal left heart catheterization a 50-year odyssey
    John Ross
    University of California San Diego, School of Medicine, La Jolla, California 92093, USA
    J Am Coll Cardiol 51:2107-15. 2008
    ....
  32. ncbi Meltrin beta expressed in cardiac neural crest cells is required for ventricular septum formation of the heart
    Kouji Komatsu
    Department of Growth Regulation, Institute for Frontier Medical Science, Kyoto University, Sakyo ku, Kyoto 606 8507, Japan
    Dev Biol 303:82-92. 2007
    ..These results genetically demonstrated a critical role of cardiac neural crest cells expressing Meltrin beta in triggering fusion of the proximal OT cushions and in formation of the ventricular septum...
  33. ncbi A novel role for VEGF in endocardial cushion formation and its potential contribution to congenital heart defects
    Y Dor
    Department of Molecular Biology, Hebrew University Hadassah Medical School, Jerusalem 91120, Israel
    Development 128:1531-8. 2001
    ..Moreover, ischemia-induced VEGF may be the molecular link between hypoxia and congenital defects in heart septation...
  34. ncbi Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation
    Michela Noseda
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
    Circ Res 94:910-7. 2004
    ....
  35. ncbi False tendons: an endoscopic cadaveric approach
    Marios Loukas
    Department of Anatomical Sciences, St George s University School of Medicine, Grenada, West Indies
    Clin Anat 20:163-9. 2007
    ..Histologically, in 30% of the FTs, conduction tissue fiber was observed to be present, which may implicate them in the appearance of arrhythmias...
  36. ncbi Survival after transcoronary ablation of septal hypertrophy in hypertrophic obstructive cardiomyopathy (TASH): a 10 year experience
    Horst Kuhn
    Chefarzt a D der Klinik für Kardiologie und Internistische Intensivmedizin, Klinikum Bielefeld Mitte, Jörg Tömlingerstr 16, 82152 Planegg, Germany
    Clin Res Cardiol 97:234-43. 2008
    ..Theoretically, the method may be harmful, because widening of the obstructed left ventricular outflow tract is achieved by a septal infarction and subsequently by a potentially arrhythmogenic scar...
  37. ncbi One-year follow-up of percutaneous septal ablation for symptomatic hypertrophic obstructive cardiomyopathy in 312 patients: predictors of hemodynamic and clinical response
    L Faber
    Department of Cardiology, Heart and Diabetes Center NRW, Ruhr University Bochum, GeorgStr 11, 32545, Bad Oeynhausen, Germany
    Clin Res Cardiol 96:864-73. 2007
    ....
  38. ncbi Extended septal myectomy for hypertrophic obstructive cardiomyopathy with anomalous mitral papillary muscles or chordae
    Kenji Minakata
    Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minn, USA
    J Thorac Cardiovasc Surg 127:481-9. 2004
    ..We reviewed our results of procedures designed to relieve obstruction with preservation of the mitral valve...
  39. ncbi Sustained improvement after combined anterior mitral leaflet extension and myectomy in hypertrophic obstructive cardiomyopathy
    Chris van der Lee
    Thoraxcenter, Erasmus Medical Center Rotterdam, The Netherlands
    Circulation 108:2088-92. 2003
    ..The study presents the long-term clinical results and outcome of this technique...
  40. ncbi Short- and long-term hemodynamic effects of intra-aortic balloon support in ventricular septal defect complicating acute myocardial infarction
    Holger Thiele
    Department of Internal Medicine, University of Leipzig, Heart Center, Germany
    Am J Cardiol 92:450-4. 2003
    ..In patients who can be stabilized or remain stable, there is no habituation to the effects of the intra-aortic balloon pump; thus, later surgical closure of the ventricular septal defect might be possible in some patients...
  41. ncbi Percutaneous versus surgical treatment for patients with hypertrophic obstructive cardiomyopathy and enlarged anterior mitral valve leaflets
    Chris van der Lee
    Thoraxcenter, Room Ba 302, Erasmus MC, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Circulation 112:482-8. 2005
    ..Myectomy with MLE previously demonstrated superior hemodynamic results compared with standard myectomy, but its value relative to PTSMA is unknown...
  42. ncbi Pressure-guided nonsurgical myocardial reduction induced by small septal infarctions in hypertrophic obstructive cardiomyopathy
    P Boekstegers
    Internal Medicine I, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    J Am Coll Cardiol 38:846-53. 2001
    ..We sought to assess the safety and efficacy of pressure-guided nonsurgical myocardial reduction (NSMR) with the induction of small septal infarctions in patients with hypertrophic obstructive cardiomyopathy (HOCM)...
  43. ncbi Surgical versus alcohol septal ablation for hypertrophic obstructive cardiomyopathy: the pendulum swings
    Magdi H Yacoub
    Circulation 112:450-2. 2005
  44. ncbi Comparison of ethanol septal reduction therapy with surgical myectomy for the treatment of hypertrophic obstructive cardiomyopathy
    S F Nagueh
    Section of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
    J Am Coll Cardiol 38:1701-6. 2001
    ....
  45. ncbi Hypertrophic cardiomyopathy--the benefits of a multidisciplinary approach
    Eugene Braunwald
    Brigham and Women s Hospital, Boston, MA 02115, USA
    N Engl J Med 347:1306-7. 2002
  46. ncbi Role of transcoronary ablation of septal hypertrophy in patients with hypertrophic cardiomyopathy, New York Heart Association functional class III or IV, and outflow obstruction only under provocable conditions
    Frank H Gietzen
    Department of Internal Medicine and Cardiology, The Bielefeld Hospital, Academic Teaching Hospital of the University of Muenster, Bielefeld, Germany
    Circulation 106:454-9. 2002
    ..It remains a point of debate whether an outflow obstruction at rest is a necessary criterion for interventional therapy...
  47. ncbi Septal myotomy-myectomy and transcoronary septal alcohol ablation in hypertrophic obstructive cardiomyopathy. A comparison of clinical, haemodynamic and exercise outcomes
    S Firoozi
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    Eur Heart J 23:1617-24. 2002
    ..The aim of this non-randomized cohort study was to compare subjective and objective outcomes in patients undergoing these therapies...
  48. ncbi Percutaneous transluminal septal ablation in hypertrophic obstructive cardiomyopathy
    H Seggewiss
    Department of Cardiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany
    Thorac Cardiovasc Surg 47:94-100. 1999
    ....
  49. ncbi Anatomy of the first septal perforating artery: a study with implications for ablation therapy for hypertrophic cardiomyopathy
    M Singh
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 76:799-802. 2001
    ..Similar findings were noted in patients with HCM. A detailed evaluation of the distribution of the FSPA may be necessary in all patients with HCM who are undergoing alcohol septal ablation...
  50. ncbi Using a human cardiopulmonary model to study and predict normal and diseased ventricular mechanics, septal interaction, and atrio-ventricular blood flow patterns
    C Luo
    Department of Electrical and Computer Engineering, Rice University, 6100 Main St, Houston, TX 77005 1892, USA
    Cardiovasc Eng 7:17-31. 2007
    ..It could also simulate the hemodynamic and respiratory effects of ventricular and pulmonary assist devices, and thus help with their development...
  51. ncbi Surgery insight: Septal myectomy for obstructive hypertrophic cardiomyopathy--the Mayo Clinic experience
    Joseph A Dearani
    Division of Cardiovascular Surgery, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Nat Clin Pract Cardiovasc Med 4:503-12. 2007
    ..These results should serve as a basis for comparison with newer nonsurgical treatment regimens...
  52. ncbi Sustained ventricular tachycardia following alcohol septal ablation for hypertrophic obstructive cardiomyopathy
    Ron D B Simon
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Pacing Clin Electrophysiol 28:1354-6. 2005
    ..This case demonstrates probable scar-induced reentrant VT post-alcohol septal ablation, a likely rare but hypothesized complication of this procedure...
  53. ncbi Echocardiographic detection and long-term outcome of coronary artery-left ventricle fistula after septal myectomy in hypertrophic obstructive cardiomyopathy
    J J Bax
    Department of Cardiology, University Hospital Leiden, The Netherlands
    J Am Soc Echocardiogr 14:308-10. 2001
    ..Transesophageal echo-cardiography may be the preferred method to diagnose and evaluate these fistulas. Moreover, in contrast to fistulas to the right ventricle, conservative management carried a good prognosis in this patient...
  54. ncbi A prospective follow-up of alcohol septal ablation for symptomatic hypertrophic obstructive cardiomyopathy--the Baylor experience (1996-2002)
    Valerian L Fernandes
    Section of Cardiology, Medical University of South Carolina, Charleston, South Carolina 77030, USA
    Clin Cardiol 28:124-30. 2005
    ..There is a paucity of data on the long-term outcome of alcohol septal ablation (ASA) for symptomatic hypertrophic obstructive cardiomyopathy (HOCM)...
  55. ncbi Percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy: acute results and 3-month follow-up in 25 patients
    H Seggewiss
    Department of Cardiology, Heart and Diabetes Center Nordrhein Westfalch, University Hospital of the Ruhr University of Bochum, Bad Oeynhausen, Germany
    J Am Coll Cardiol 31:252-8. 1998
    ..We report the acute results and midterm clinical course after percutaneous transluminal septal myocardial ablation (PTSMA) in symptomatic patients with hypertrophic obstructive cardiomyopathy (HOCM)...
  56. ncbi Comparison of dual-chamber pacing with nonsurgical septal reduction effect in patients with hypertrophic obstructive cardiomyopathy
    P Petkow Dimitrow
    Institute of Cardiology, Collegium Medicum Jagiellonian University, Krakow, Poland
    Int J Cardiol 94:31-4. 2004
    ..The aim of the study was to compare the influence of dual-chamber pacing vs. nonsurgical septal reduction on hemodynamic and morphological parameters in patients with obstructive form of hypertrophic cardiomyopathy...
  57. ncbi [Left coronaro-ventricular fistula after septal myectomy]
    A Sarkis
    Service de cardiologie, , Paris
    Arch Mal Coeur Vaiss 85:457-60. 1992
    ....
  58. ncbi Complications of percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy
    Weiwei Zhang
    Department of Cardiology, Liaoning Provincial Hospital, Liaoning Cardiac Centre, Shenyang 110016, China
    Chin Med J (Engl) 115:1283-6. 2002
    ..To assess the complications of percutaneous tansluminal septal myocardial ablation (PTSMA) for the treatment of hypertrophic obstructive cardiomyopathy (HOCM)...
  59. ncbi Long-term follow-up of acquired coronary artery fistula after septal myectomy for hypertrophic cardiomyopathy
    Ashish Awasthi
    Division of Cardiology, State University of New York, USA
    J Am Soc Echocardiogr 15:1104-7. 2002
    ..Medical therapy appears to be the appropriate treatment strategy in these patients...
  60. ncbi Acute decompensation of hypertrophic obstructive cardiomyopathy secondary to A-V disassociation: successful treatment with a combination of alcohol septal ablation and permanent pacemaker
    Sameer Rohatgi
    Cardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Interv Cardiol 18:401-6. 2005
    ..This case report is also a unique description of alcohol septal ablation being performed emergently to improve hemodynamics and the urgent implantation of a permanent pacemaker to return A-V synchrony...
  61. ncbi Live three-dimensional transthoracic echocardiographic demonstration of septal perforator coronary artery-left ventricle fistulas following myectomy
    Vinod Patel
    Division of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Echocardiography 22:273-5. 2005
    ..Our case demonstrates the potential usefulness of 3D TTE as a supplement to 2D TTE in the assessment of septal coronary artery-left ventricle fistulas...
  62. ncbi [Percutaneous transluminal septal myocardial ablation: early results and long-term follow-up]
    Łukasz Tekieli
    Klinika Chorób Serca i Naczyń, Krakowski Szpital Specjalistyczny im Jana Pawła II, Uniwersytet Jagiellonski, Collegium Medicum, Krakow
    Przegl Lek 63:628-32. 2006
    ..The aim of our study was to analyze early results, complications and long-term follow-up in patients after PTSMA...
  63. ncbi Real-time 3-dimensional echocardiographic features of fetal cardiac tumor
    Toshiyuki Hata
    Department of Perinatology and Gynecology, Kagawa University School of Medicine, 1750 1 Ikenobe, Miki, Kagawa 761 0793, Japan
    J Clin Ultrasound 35:338-40. 2007
    ..Real-time 3D echocardiography with instantaneous volume rendering showed the cardiac tumors in motion. The advantages and disadvantages of real-time 3D fetal echocardiography are discussed...
  64. ncbi Pressure gradient response after alcohol septal ablation in hypertrophic obstructive cardiomyopathy
    Josef Veselka
    Kardiol Pol 64:1161-2; author reply 1162. 2006
  65. ncbi Residual fibrosis affects a long-term result of left ventricular volume reduction surgery for dilated cardiomyopathy in a rat experimental study
    Taiko Horii
    Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Eur J Cardiothorac Surg 26:1174-9. 2004
    ..The aim of this study is to evaluate the relationship between left ventricular (LV) wall property and the results of LV volume reduction surgery (LVR) to treat dilated cardiomyopathy (DCM) in an experimental model...
  66. ncbi Treatment of right ventricle to coronary artery connections in infants with pulmonary atresia and intact ventricular septum
    John E Foker
    Division of Cardiothoracic Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Thorac Cardiovasc Surg 136:749-56. 2008
    ..Our purpose is to present the first series of right ventricle to coronary artery connections ligated off bypass before right ventricular decompression and to evaluate the consequences of this approach...
  67. ncbi Usefulness of real-time three-dimensional echocardiography for evaluation of myectomy in patients with hypertrophic cardiomyopathy
    Jian Xin Qin
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Cardiol 94:964-6. 2004
    ..4 +/- 0.7 vs 5.1 +/- 1.2 cm(2), p <0.01), significantly increased after myectomy (4.8 +/- 1.8 cm2, p <0.01) and was associated with a reduction of the pressure gradient at rest from 63 +/- 41 to 15 +/- 5 mm Hg (p <0.01)...
  68. ncbi Non-compaction of the right atrium and left ventricle in Ebstein's malformation
    Claudia Stollberger
    Second Medical Department, Krankenanstalt Rudolfstiftung, Vienna, Austria
    J Heart Valve Dis 15:719-20. 2006
    ..Neurologically, hypoacusis, positive pyramidal signs, postural tremor and brisk tendon reflexes were identified...
  69. ncbi Beneficial effect of cibenzoline on left ventricular pressure gradient with sigmoid septum
    Chika Konishi
    Department of Cardiology, Kyoto Prefectural Rakuto Hospital, Japan
    Circ J 68:968-71. 2004
    ..This case shows that cibenzoline may be useful in the treatment of left ventricular outflow tract obstruction caused by sigmoid septum...
  70. ncbi Pathomorphological variants of midventricular obstruction of interventricular septum during hypertrophic cardiomyopathy
    V D Rozenberg
    Department of General Pathology and Pathomorphology, Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia
    Bull Exp Biol Med 137:614-8. 2004
    ....
  71. ncbi Echo-guided percutaneous septal ablation for symptomatic hypertrophic obstructive cardiomyopathy: 7 years of experience
    Lothar Faber
    Department of Cardiology, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, GeorgStr 11, D 32545 Bad Oeynhausen, Germany
    Eur J Echocardiogr 5:347-55. 2004
    ....
  72. ncbi Alcohol septal ablation for hypertrophic obstructive cardiomyopathy: a systematic review of published studies
    Mahboob Alam
    Baylor College of Medicine Cardiology, Houston, Texas 77030, USA
    J Interv Cardiol 19:319-27. 2006
    ..The purpose of this study is to analyze all the published literature on outcomes and complications after ASA...
  73. ncbi Septal alcohol ablation in hypertrophic obstructive cardiomyopathy: improving cardiac function by generating a myocardial scar
    Georgios K Efthimiadis
    Eur Heart J 28:1270-1; author reply 1271. 2007
  74. ncbi Septal myectomy for obstructive hypertrophic cardiomyopathy in pediatric patients: early and late results
    Kenji Minakata
    Division of Cardiovascular Surgery, Mayo Clinic and Foundation, Rochester, Minnesota, USA
    Ann Thorac Surg 80:1424-9; discussion 1429-30. 2005
    ..Transaortic left ventricular septal myectomy provides excellent outcomes for adults with obstructive HCM. We sought to assess the effect of septal myectomy on late survival and outcome in pediatric patients with obstructive HCM...
  75. ncbi Right atrial rhabdomyoma acting as the substrate for Wolff-Parkinson-White syndrome in a 3-month-old infant
    Poothirikovil Venugopalan
    Department of Child Health, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman
    Acta Cardiol 60:543-5. 2005
    ..Right atrial rhabdomyomas are rare and to our knowledge this is the first reported instance where we could document clearly that the tumour itself formed the substrate for the WPW syndrome...
  76. pmc Comparison of the clinical features of apical hypertrophic cardiomyopathy versus asymmetric septal hypertrophy in Korea
    Hyun Suk Yang
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Korean J Intern Med 20:111-5. 2005
    ..We sought to test whether patients with apical hypertrophic cardiomyopathy (APH) have different clinical features compared to those with typical asymmetric septal hypertrophy (ASH)...
  77. ncbi Resection of a lipomatous hypertrophic interatrial septum involving the right ventricle
    Niels J Verberkmoes
    Department of Cardiothoracic Surgery, Catharina Hospital, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands
    Interact Cardiovasc Thorac Surg 6:654-7. 2007
    ..The postoperative period was complicated by superior vena cava syndrome for which she underwent re-operation. The post mortem histopathological diagnosis was a lipomatous hypertrophic interatrial septum...
  78. ncbi Catheter-based septal ablation for symptomatic hypertrophic obstructive cardiomyopathy: follow-up results of the TASH-registry of the German Cardiac Society
    L Faber
    Kardiologische Klinik Herz und Diabeteszentrum NRW, Universitatsklinik der Ruhr Universitat Bochum, Georgstrasse 11, 32545 Bad Oeynhausen, Germany
    Z Kardiol 94:516-23. 2005
    ..An analysis of the acute results has already been published. We now report on the mid-term course (3-6 months) of 242 pts. registered through September 1999...
  79. ncbi Comparison of percutaneous transluminal septal myocardial ablation versus septal myectomy for the treatment of patients with hypertrophic obstructive cardiomyopathy--a meta analysis
    Zhiyu Zeng
    Center for Arrhythmia Diagnosis and Treatment, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Int J Cardiol 112:80-4. 2006
    ..The effects of percutaneous transluminal septal myocardial ablation (PTSMA) with septal myectomy in patients with hypertrophic obstructive cardiomyopathy (HOCM) are not thoroughly compared...
  80. ncbi Quantitative estimation of left atrial linear dimension on a transthoracic echocardiogram using an electrocardiographic formulaic assessment
    Vignendra Ariyarajah
    Division of Cardiology, Department of Medicine, St Boniface General Hospital University of Manitoba, Winnipeg, Manitoba, Canada
    Am J Cardiol 100:894-8. 2007
    ..The LA regression formula is an indirect asset that could perhaps supplement LA quantification on TTE in certain circumstances...
  81. ncbi The concentration of atrial and brain natriuretic peptide in patients with idiopathic hypertension
    Robert Irzmanski
    Department of Internal Diseases and Cardiological Rehabilitation, University Hospital No 5, Medical University of Łódź, Łódź, Poland
    Med Sci Monit 13:CR449-56. 2007
    ....
  82. ncbi Transatrial septal catheterization using a new radiofrequency probe
    Warren Sherman
    Cardiovascular Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
    Catheter Cardiovasc Interv 66:14-7. 2005
    ..We have used an alternative method for transseptal access to the left atrium, which employs a novel radiofrequency catheter system. In this report, we describe the system and its use in our initial series of patients...
  83. ncbi Partial myocardial fibrosis in hypertrophic cardiomyopathy demonstrated by 18F-fluoro-deoxyglucose positron emission tomography and multislice computed tomography
    Nobusada Funabashi
    Int J Cardiol 107:284-6. 2006
  84. ncbi Right atrial dissecting intramural hematoma resulting in interventricular communication without ventricular septal defect: a rare complication of myocardial infarction
    Dimitrios Patsouras
    Cardiology 104:191-2. 2005
  85. ncbi The atrioventricular nodal reentrant tachycardia circuit: a proposal
    Demosthenes G Katritsis
    Department of Cardiology, Athens Euroclinic, 9 Athanassiadou Street, Athens 11521, Greece
    Heart Rhythm 4:1354-60. 2007
    ..In the present article, we summarize the available evidence and propose a comprehensive model of the tachycardia circuit for all forms of atrioventricular nodal reentrant tachycardia based on the concept of atrionodal inputs...
  86. ncbi Alcohol septal ablation after failed surgical myectomy
    Dominique Joyal
    Division of Cardiology, Loyola University Medical Center, Maywood, Illinois 60153, USA
    Catheter Cardiovasc Interv 69:999-1002. 2007
    ....
  87. ncbi Total correction of complete atrioventricular septal defect with tetralogy of Fallot
    Edvin Prifti
    Division of Pediatric Cardiac Surgery, G Pasquinucci Hospital, CREAS IFC CNR, Massa, Italy
    J Heart Valve Dis 12:640-8. 2003
    ..The authors' experience in surgical management of tetralogy of Fallot in association with complete atrioventricular septal defect (CAVSD-TOF) is reported...
  88. ncbi Left atrial mechanical function in patients with essential hypertension
    Mustafa Kemal Erol
    Ataturk University Medical School Hospital, Department of Cardiology, Erzurum, Turkey
    Acta Cardiol 57:323-7. 2002
    ..This study was carried out to assess the left atrial (LA) mechanical function in patients with essential hypertension with two-dimensional echocardiography by means of left atrial volume measurements...
  89. ncbi Does impaired left ventricular relaxation affect P wave dispersion in patients with hypertension?
    Abdullah Dogan
    Department of Cardiology, Sevket Demirel Heart Center, Isparta, Turkey
    Ann Noninvasive Electrocardiol 8:189-93. 2003
    ..P wave dispersion (PD) is considered to reflect the heterogeneous conduction in atria. We investigated whether there was a correlation between the left ventricular (LV) relaxation and PD...
  90. ncbi Feasibility and safety of immediate perioperative implantation of intravascular stents in cavopulmonary pathways
    Muhammad Walayat
    Department of Cardiology, Royal Hospital for Sick Children, Yorkhill, Glasgow, Scotland
    Catheter Cardiovasc Interv 60:94-8; discussion 99-100. 2003
    ..We report the successful use of endovascular stents during the immediate postoperative period in patients undergoing cavopulmonary anastomoses...
  91. ncbi Fenestrated Amplatzer device for percutaneous creation of interatrial communication in patients after Fontan operation
    Ritu Chatrath
    Division of Pediatric Cardiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Catheter Cardiovasc Interv 60:88-93. 2003
    ..At follow-up, device fenestration was occluded in both patients. In both patients, the device fenestration was reopened and patency maintained by placement of two stents within the communicating channel...
  92. pmc Hypertrophic obstructive cardiomyopathy with infundibular stenosis treated by alcohol ablation therapy
    Sung Hak Park
    Department of Internal Medicine, Inha Medical Center, Inha University, Inchon, Korea
    J Korean Med Sci 18:585-8. 2003
    ..This is the first case in which HOCM with infundibular stenosis of the right ventricle was treated by alcohol ablation therapy...
  93. ncbi Depth variation bias and interaction with gain setting in ultrasonic tissue characterization by integrated backscatter analysis
    Marcello Chinali
    Echocardiography Laboratory, Department of Clinical and Experimental Medicine, Federico II University Hospital, School of Medicine, Naples, Italy
    J Am Soc Echocardiogr 16:54-60. 2003
    ..Using appropriate regression modeling may allow analysis in optimal imaging conditions, tolerating between-patient comparisons even in limited diastolic frames...
  94. ncbi Evolution of ventricular septal defect with special reference to spontaneous closure rate, subaortic ridge and aortic valve prolapse
    A G Eroglu
    Department of Pediatrics, Istanbul University Cerrahpas, a Medical Faculty, Aksaray, Istanbul, Turkey
    Pediatr Cardiol 24:31-5. 2003
    ..3% (33) of 450 patients with perimembranous defect. There was no statistical significance between the age at closure and the age of detection of aneurysmal transformation in the patients with perimembranous defect (p = 0.25)...
  95. ncbi Doppler tissue imaging: regional myocardial function in hypertrophic cardiomyopathy and in athlete's heart
    Nuno Cardim
    Department of Cardiology, Hospital Pulido Valente, Lisbon, Portugal
    J Am Soc Echocardiogr 16:223-32. 2003
    ....
  96. ncbi Complete heart block: determinants and clinical impact in patients with hypertrophic obstructive cardiomyopathy undergoing nonsurgical septal reduction therapy
    Su Min Chang
    Section of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
    J Am Coll Cardiol 42:296-300. 2003
    ..The purpose of this paper is to examine the incidence and determinants of permanent complete heart block (CHB) after nonsurgical septal reduction therapy (NSRT), and to evaluate the clinical impact of permanent pacemaker (PPM) placement...
  97. ncbi Phased-array intracardiac echocardiography for defining cavotricuspid isthmus anatomy during radiofrequency ablation of typical atrial flutter
    Joseph B Morton
    Department of Cardiology, The Royal Melbourne Hospital, Melbourne, Australia
    J Cardiovasc Electrophysiol 14:591-7. 2003
    ..The aim of this study was to assess the utility of phased-array intracardiac echocardiography (ICE) for imaging the CTI and monitoring RFA of AFL...
  98. ncbi Remodelling after surgical repair of atrial septal defects within the oval fossa
    Christine H Attenhofer Jost
    Division of Cardiology, University Hospital, Zurich Switzerland
    Cardiol Young 12:506-12. 2002
    ..Despite preserved systolic function, persistent diastolic dysfunction is common and is associated with elevated levels of brain natriuretic peptide, which may explain the late occurrence of atrial arrhythmias...
  99. ncbi Comparison of left ventricular diastolic function in obstructive hypertrophic cardiomyopathy in patients undergoing percutaneous septal alcohol ablation versus surgical myotomy/myectomy
    Marta Sitges
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Cardiol 91:817-21. 2003
    ..Thus, diastolic function indexes obtained by echocardiography changed after septal reduction interventions in patients with obstructive HC; this change was similar to that after surgical myectomy and ASR...
  100. ncbi Images in cardiovascular medicine. Atrial septal defect device closure in a patient with lipomatous hypertrophy of the atrial septum
    William Stuart Moir
    Centre for Heart and Chest Research, Department of Medicine, Monash University and Monash Medical Centre, Clayton, Victoria, Australia
    Circulation 107:e217. 2003
  101. ncbi Transthoracic echocardiographic demonstration of septal perforator coronary arteries-left ventricle fistula
    Steven K Sooudi
    Division of Cardiovascular Disease, Heart Station SWB S102, University of Alabama at Birmingham, 619 South 19th Street, Birmingham, AL 35249, USA
    Echocardiography 20:197-8. 2003
    ..In some views this finding mimicked aortic regurgitation...

Research Grants13

  1. Function of Fibulins
    Mon Li Chu; Fiscal Year: 2004
    ..The proposed studies will provide insights into the role of fibulins in human disease and the mechanism of cardiovascular development. ..
  2. Controlled Reperfusion for Whole Body Ischemic Injury
    Gerald Buckberg; Fiscal Year: 2005
    ..If this novel method of management is correct, the scheme of diagnosis and management of this almost always fatal cardiac arrest complex will change markedly. ..
  3. CRANIOFACIAL MORPHOGENESIS IN PRENATAL ALCOHOL EXPOSURE
    Susan Smith; Fiscal Year: 2005
    ..Results also may provide possible explanations for genetic-based variations in fetal responses to prenatal ethanol exposure. ..
  4. 14th Biennial FASEB Summer Research Conference on Retinoids
    Susan Smith; Fiscal Year: 2008
    ..Its goal is to stimulate scientific exchange and new investigations that will provide needed insights into retinoid roles in disease prevention and treatment. [unreadable] [unreadable] [unreadable]..
  5. TGFB RECEPTOR EXPRESSION AND FUNCTION IN CARDIOGENESIS
    Joey Barnett; Fiscal Year: 2005
    ..Our long-term goal to understand the role of TGFbeta in cushion transformation and the genesis of congenital heart defects due to abnormal cushion transformation. ..
  6. Percutaneous MR Guided Creation of a Meso-Caval Shunt
    Aravind Arepally; Fiscal Year: 2008
    ....
  7. COCAINE EXPOSED INFANTS--CARDIAC PROBLEMS AND OUTCOME
    Sudhir Mehta; Fiscal Year: 2001
    ..Therefore, it is crucial to understand the natural history of the cardiovascular abnormalities before measures can be directed toward their treatment and prevention. ..
  8. Cerebellar stimulation for motor recovery from stroke
    Andre Machado; Fiscal Year: 2008
    ..Thus, promising results from a study such as the one proposed ultimately could lead directly to trials in human patients with stroke as the hardware and techniques are already well established. [unreadable] [unreadable] [unreadable]..
  9. TRAINING PROGRAM IN CARDIOVASCULAR PHARMACOLOGY
    Joey Barnett; Fiscal Year: 2008
    ..Our overall goal is to train scientists who will be leaders in academia, industry, or regulatory affairs. ..
  10. National Pharmacology Directors of Graduate Programs Meeting
    Joey Barnett; Fiscal Year: 2007
    ..A continuing dialogue among Directors of training programs and other scientists with an interest in training is identified as a desired major outcome. [unreadable] [unreadable] [unreadable]..
  11. Pediatric Thin-Film TiNi Catheter-Based Heart Valve
    Daniel Levi; Fiscal Year: 2005
    ..Phase II studies will focus on accelerated wear testing, long-term in vivo animal testing, and manufacturing issues. ..
  12. Atrionodal Bundles:Histologic and Physiologic Validation
    DARLENE RACKER; Fiscal Year: 2005
    ..These studies are expected to provide a basis for evaluating transmission, arrhythmogenesis, and drug interactions at the tissue level. ..
  13. Deep brain stimulation of the ventral anterior limb of the internal capsule for m
    Andre Machado; Fiscal Year: 2009
    ..In this proposal, we describe an innovative approach to alleviate suffering and disability among those with severe and refractory chronic neuropathic pain. ..