pelvic floor

Summary

Summary: Soft tissue formed mainly by the pelvic diaphragm, which is composed of the two levator ani and two coccygeus muscles. The pelvic diaphragm lies just below the pelvic aperture (outlet) and separates the pelvic cavity from the PERINEUM. It extends between the PUBIC BONE anteriorly and the COCCYX posteriorly.

Top Publications

  1. ncbi Patient-centered goals for pelvic floor dysfunction surgery: what is success, and is it achieved?
    Kathie L Hullfish
    Department of Obstetrics and Gynecology, University of Virginia Health System, Charlottesville, 22908, USA
    Am J Obstet Gynecol 187:88-92. 2002
  2. ncbi Pelvic floor symptom changes in pessary users
    Yuko M Komesu
    Division of Urogynecology and Pelvic Floor Disorders, Department of Obstetrics and Gynecology, University of New Mexico Health Sciences Center School of Medicine, Albuquerque, NM, USA
    Am J Obstet Gynecol 197:620.e1-6. 2007
  3. ncbi An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction
    Bernard T Haylen
    St Vincent s Clinic, Suite 904, 438 Victoria Street, Darlinghurst, Sydney, 2010, NSW, Australia
    Int Urogynecol J 21:5-26. 2010
  4. ncbi Postural and respiratory functions of the pelvic floor muscles
    P W Hodges
    Division of Physiotherapy, The University of Queensland, Brisbane, Queensland, Australia
    Neurourol Urodyn 26:362-71. 2007
  5. ncbi An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction
    Bernard T Haylen
    University of New South Wales, Sydney, New South Wales, Australia
    Neurourol Urodyn 29:4-20. 2010
  6. pmc The appearance of levator ani muscle abnormalities in magnetic resonance images after vaginal delivery
    John O L Delancey
    University of Michigan, Ann Arbor, Michigan 48109 0276, USA
    Obstet Gynecol 101:46-53. 2003
  7. ncbi Preoperative pelvic floor muscle exercise for early continence after radical prostatectomy: a randomised controlled study
    Antonia Centemero
    Department of Urology, Vita Salute University, San Raffaele Turro Hospital, Milan, Italy
    Eur Urol 57:1039-43. 2010
  8. pmc Prevalence of symptomatic pelvic floor disorders in US women
    Ingrid Nygaard
    Department of Obstetrics and Gynecology, University of Utah School of Medicine, 30 N 1900 E, Salt Lake City, UT 84132 2209, USA
    JAMA 300:1311-6. 2008
  9. ncbi Comparison of levator ani muscle defects and function in women with and without pelvic organ prolapse
    John O L Delancey
    Department of Obstetrics and Gynecology, Department of Biomechanical Engineering, Institute of Gerontology, School of Nursing, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
    Obstet Gynecol 109:295-302. 2007
  10. ncbi Extended abdominoperineal resection with gluteus maximus flap reconstruction of the pelvic floor for rectal cancer
    T Holm
    Department of Surgery, Karolinska University Hospital, Stockholm, Sweden
    Br J Surg 94:232-8. 2007

Detail Information

Publications318 found, 100 shown here

  1. ncbi Patient-centered goals for pelvic floor dysfunction surgery: what is success, and is it achieved?
    Kathie L Hullfish
    Department of Obstetrics and Gynecology, University of Virginia Health System, Charlottesville, 22908, USA
    Am J Obstet Gynecol 187:88-92. 2002
    The purpose of this study was to describe patient-identified goals for pelvic floor dysfunction surgical procedures and patient-reported achievement of those goals.
  2. ncbi Pelvic floor symptom changes in pessary users
    Yuko M Komesu
    Division of Urogynecology and Pelvic Floor Disorders, Department of Obstetrics and Gynecology, University of New Mexico Health Sciences Center School of Medicine, Albuquerque, NM, USA
    Am J Obstet Gynecol 197:620.e1-6. 2007
    The objective of the study was to compare pelvic floor symptom changes in patients who continue vs discontinue pessary use, and determine whether changes predict pessary continuation.
  3. ncbi An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction
    Bernard T Haylen
    St Vincent s Clinic, Suite 904, 438 Victoria Street, Darlinghurst, Sydney, 2010, NSW, Australia
    Int Urogynecol J 21:5-26. 2010
    Next to existing terminology of the lower urinary tract, due to its increasing complexity, the terminology for pelvic floor dysfunction in women may be better updated by a female-specific approach and clinically based consensus report.
  4. ncbi Postural and respiratory functions of the pelvic floor muscles
    P W Hodges
    Division of Physiotherapy, The University of Queensland, Brisbane, Queensland, Australia
    Neurourol Urodyn 26:362-71. 2007
    ..their contribution to modulation of intra-abdominal pressure (IAP) and stiffness of the sacroiliac joints, the pelvic floor muscles (PFM) have been argued to provide a contribution to control of the lumbar spine and pelvis...
  5. ncbi An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction
    Bernard T Haylen
    University of New South Wales, Sydney, New South Wales, Australia
    Neurourol Urodyn 29:4-20. 2010
    Next to existing terminology of the lower urinary tract, due to its increasing complexity, the terminology for pelvic floor dysfunction in women may be better updated by a female-specific approach and clinically based consensus report.
  6. pmc The appearance of levator ani muscle abnormalities in magnetic resonance images after vaginal delivery
    John O L Delancey
    University of Michigan, Ann Arbor, Michigan 48109 0276, USA
    Obstet Gynecol 101:46-53. 2003
    ..To describe the appearance and occurrence of abnormalities in the levator ani muscle seen on magnetic resonance imaging (MRI) in nulliparous women and in women after their first vaginal birth...
  7. ncbi Preoperative pelvic floor muscle exercise for early continence after radical prostatectomy: a randomised controlled study
    Antonia Centemero
    Department of Urology, Vita Salute University, San Raffaele Turro Hospital, Milan, Italy
    Eur Urol 57:1039-43. 2010
    ..Despite improvements in surgical techniques, urinary incontinence (UI) is not uncommon after radical prostatectomy (RP), and it may dramatically worsen quality of life (QoL)...
  8. pmc Prevalence of symptomatic pelvic floor disorders in US women
    Ingrid Nygaard
    Department of Obstetrics and Gynecology, University of Utah School of Medicine, 30 N 1900 E, Salt Lake City, UT 84132 2209, USA
    JAMA 300:1311-6. 2008
    b>Pelvic floor disorders (urinary incontinence, fecal incontinence, and pelvic organ prolapse) affect many women...
  9. ncbi Comparison of levator ani muscle defects and function in women with and without pelvic organ prolapse
    John O L Delancey
    Department of Obstetrics and Gynecology, Department of Biomechanical Engineering, Institute of Gerontology, School of Nursing, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
    Obstet Gynecol 109:295-302. 2007
    To compare levator ani defects and pelvic floor function among women with prolapse and controls.
  10. ncbi Extended abdominoperineal resection with gluteus maximus flap reconstruction of the pelvic floor for rectal cancer
    T Holm
    Department of Surgery, Karolinska University Hospital, Stockholm, Sweden
    Br J Surg 94:232-8. 2007
    ..technique is the extended posterior perineal approach with gluteus maximus flap reconstruction of the pelvic floor. The aim of this study was to report the technique and early experience of extended APR in a select cohort of ..
  11. ncbi Pelvic floor disorders, diabetes, and obesity in women: findings from the Kaiser Permanente Continence Associated Risk Epidemiology Study
    Jean M Lawrence
    Department of Research and Evaluation, Kaiser Permanente Southern California, 100 S Los Robles, 2nd Floor, Pasadena CA 91101, USA
    Diabetes Care 30:2536-41. 2007
    We examined associations between obesity and diabetes and female pelvic floor disorders (PFDs), stress urinary incontinence (SUI), overactive bladder (OAB), and anal incontinence (AI) in community-dwelling women.
  12. pmc Randomized controlled trial shows biofeedback to be superior to pelvic floor exercises for fecal incontinence
    Steve Heymen
    Department of Medicine Division of Gastroenterology and Hepatology and Center for Functional Gastrointestinal and Motility Disorders, University of North Carolina, Chapel Hill, North Carolina 27599 7080, USA
    Dis Colon Rectum 52:1730-7. 2009
    This study aimed to compare manometric biofeedback with pelvic floor exercises for the treatment of fecal incontinence in a randomized controlled trial controlling for nonspecific treatment effects.
  13. ncbi Pelvic floor exercise for urinary incontinence: a systematic literature review
    Natalia Price
    Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford, UK
    Maturitas 67:309-15. 2010
    ..Physical therapies, particularly pelvic floor muscle exercise, are the mainstay of such conservative management...
  14. ncbi A cross-sectional study of knowledge and practice of pelvic floor exercises during pregnancy and associated symptoms of stress urinary incontinence in North-East Scotland
    Heather M Whitford
    School of Nursing and Midwifery, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK
    Midwifery 23:204-17. 2007
    to establish levels of knowledge about pelvic floor exercises during pregnancy; reported practice of pelvic floor exercises in pregnancy; and prevalence of stress urinary incontinence in a sample of women in the third trimester of ..
  15. ncbi Long-term effect of early postoperative pelvic floor biofeedback on continence in men undergoing radical prostatectomy: a prospective, randomized, controlled trial
    Lúcia Helena S Ribeiro
    Division of Urology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil
    J Urol 184:1034-9. 2010
    The impact of pelvic floor muscle training on the recovery of urinary continence after radical prostatectomy is still controversial...
  16. pmc Adherence to behavioral interventions for urge incontinence when combined with drug therapy: adherence rates, barriers, and predictors
    Diane Borello-France
    Department of Physical Therapy, Duquesne University, 111 Health Sciences Bldg, Pittsburgh, PA 15282, USA
    Phys Ther 90:1493-505. 2010
    ..Behavioral intervention outcomes for urinary incontinence (UI) depend on active patient participation...
  17. ncbi Urinary incontinence in men after formal one-to-one pelvic-floor muscle training following radical prostatectomy or transurethral resection of the prostate (MAPS): two parallel randomised controlled trials
    Cathryn Glazener
    Health Services Research Unit, University of Aberdeen, Foresterhill, Aberdeen, UK
    Lancet 378:328-37. 2011
    ..Men are often advised to do pelvic-floor exercises, but evidence to support this is inconclusive. Our aim was to establish if formal one-to-one pelvic floor muscle training reduces incontinence.
  18. ncbi Efficacy of an assisted low-intensity programme of perioperative pelvic floor muscle training in improving the recovery of continence after radical prostatectomy: a randomized controlled trial
    Daniele Tienforti
    Department of Urology, Agostino Gemelli Hospital, Catholic University Medical School, Rome, Italy
    BJU Int 110:1004-10. 2012
    ..What's known on the subject? and What does the study add? Peri-operative pelvic floor muscle training reduces urinary incontinence for men undergoing radical prostatectomy (RP)...
  19. ncbi Estrogen receptor in pelvic floor tissues in patients with stress urinary incontinence
    Lan Zhu
    Dept of O G, Peking Union Medical College Hospital, 100730, Beijing, P R of China
    Int Urogynecol J Pelvic Floor Dysfunct 15:340-3. 2004
    ..Thirty-one biopsy specimens from pelvic floor tissues were obtained from 31 patients categorized into three groups: pelvic organ prolapse (POP), SUI and ..
  20. ncbi Comparisons of approaches to pelvic floor muscle training for urinary incontinence in women
    E Jean C Hay-Smith
    Rehabilitation Teaching and Research Unit, Department of Medicine, University of Otago, Wellington, New Zealand
    Cochrane Database Syst Rev 12:CD009508. 2011
    b>Pelvic floor muscle training is the most commonly recommended physical therapy treatment for women with stress urinary incontinence. It is also sometimes recommended for mixed and, less commonly, urge urinary incontinence...
  21. ncbi A new concept of the anatomy of the anal sphincter mechanism and the physiology of defecation: mass contraction of the pelvic floor muscles
    A Shafik
    Faculty of Medicine, Cairo University, Egypt
    Int Urogynecol J Pelvic Floor Dysfunct 9:28-32. 1998
    ..Each muscle was thereafter stimulated separately and the response of the other pelvic floor muscles registered...
  22. ncbi Electromyography of pelvic floor muscles
    Paul Enck
    Department of Internal Medicine VI, University Hospitals Tubingen, Psychosomatic Medicine, Osianderstr 5, 72076 Tubingen, Germany
    J Electromyogr Kinesiol 16:568-77. 2006
    b>Pelvic floor muscles (PFM) are intimately involved in function of lower urinary tract, the anorectum and sexual functions, therefore their neural control transcends the primarily important somatic innervation of striated muscle, as they ..
  23. ncbi Intergender differences in histological architecture of the fascia pelvis parietalis: a cadaveric study
    Eiji Hirata
    Department of Obstetrics and Gynecology, Hiroshima University, Hiroshima, Japan
    Clin Anat 24:469-77. 2011
    ....
  24. ncbi Minimal criteria for the diagnosis of avulsion of the puborectalis muscle by tomographic ultrasound
    Hans Peter Dietz
    Sydney Medical School Nepean, Penrith, Australia
    Int Urogynecol J 22:699-704. 2011
    ..Puborectalis avulsion is a likely etiological factor for female pelvic organ prolapse (FPOP). We performed a study to establish minimal sonographic criteria for the diagnosis of avulsion...
  25. ncbi Levator avulsion is a risk factor for cystocele recurrence
    H P Dietz
    Sydney Medical School Nepean, University of Sydney, Nepean Hospital, Penrith, Australia
    Ultrasound Obstet Gynecol 36:76-80. 2010
    ..To determine whether levator avulsion is a risk factor for recurrence after cystocele repair...
  26. ncbi Transobturator sling suspension for male urinary incontinence including post-radical prostatectomy
    Peter Rehder
    Department of Urology, Medical University Innsbruck, Austria
    Eur Urol 52:860-6. 2007
    ..To study the anatomical effects of placing a transobturator tape (TOT) in cadavers as well as determining the clinical outcome in men with urinary incontinence...
  27. ncbi Improved continence outcomes with preoperative pelvic floor muscle strengthening exercises
    C Sueppel
    Physician's Clinic of Iowa/Urology, Cedar Rapids, IA, USA
    Urol Nurs 21:201-10. 2001
    The results of this study involving the timing of pelvic floor muscle strengthening exercises and the return of continence showed that starting biofeedback sessions with pelvic floor muscle exercises prior to radical prostatectomy surgery ..
  28. ncbi Is there correlation between electromyography and digital palpation as means of measuring pelvic floor muscle contractility in nulliparous, pregnant, and postpartum women?
    Simone Botelho
    Federal University of Alfenas UNIFAL MG, Alfenas, Minas Gerais, Brazil
    Neurourol Urodyn 32:420-3. 2013
    The continence mechanisms depend on the integrity of the pelvic floor muscles. It is therefore important to find simple, reliable, and safe methods to assess its contractility in a clinical setting...
  29. ncbi Impact of early pelvic floor rehabilitation after transurethral resection of the prostate
    D Porru
    Divisione Urologia Policlinico S Matteo, Pavia, Italy
    Neurourol Urodyn 20:53-9. 2001
    We examined the results of teaching pelvic floor muscle exercises (PME) on micturition parameters, urinary incontinence, post-micturition dribbling, and quality of life in patients after transurethral prostatectomy (TURP)...
  30. ncbi Pelvic floor ultrasonography: an update
    K L Shek
    Sydney Medical School Nepean, University of Sydney, Sydney, NSW, Australia
    Minerva Ginecol 65:1-20. 2013
    Female pelvic floor dysfunction encompasses a number of highly prevalent clinical conditions such as female pelvic organ prolapse, urinary and fecal incontinence, and sexual dysfunction...
  31. ncbi Can pelvic floor muscle training reverse pelvic organ prolapse and reduce prolapse symptoms? An assessor-blinded, randomized, controlled trial
    Ingeborg Hoff Braekken
    Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway
    Am J Obstet Gynecol 203:170.e1-7. 2010
    The aim of this study was to investigate the effectiveness of pelvic floor muscle training in reversing pelvic organ prolapse and alleviating symptoms.
  32. ncbi Female perineal membrane: a study using pelvic floor semiserial sections from elderly nulliparous and multiparous women
    Masao Kato
    Department of Urology, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3, Kasumi, Minami Ku, Hiroshima, 734 8551, Japan
    Int Urogynecol J Pelvic Floor Dysfunct 19:1663-70. 2008
    ..We hypothesize that the PM plays a role of a shock-absorber at the interface between the levator ani and distalmost vagina. A standard diagram of the female perineal structures is necessary to be revised...
  33. ncbi Placement of probes in electrostimulation and biofeedback training in pelvic floor dysfunction
    Petra J Voorham-van der Zalm
    Department of Physiotherapy, Leiden University Medical Center, The Netherlands
    Acta Obstet Gynecol Scand 85:850-5. 2006
    ..We examined the positioning of five commonly used probes in electrostimulation and biofeedback training...
  34. ncbi A randomized clinical trial comparing pelvic floor muscle training to a Pilates exercise program for improving pelvic muscle strength
    Patrick J Culligan
    Atlantic Health Division of Urogynecology, 95 Madison Ave Suite 204, Morristown, NJ 07960, USA
    Int Urogynecol J 21:401-8. 2010
    The purpose of this study is to determine whether a Pilates exercise program and a pelvic floor muscle-training (PFMT) program could provide similar improvements in pelvic muscle strength.
  35. ncbi Pelvic floor muscle training in treatment of female stress urinary incontinence, pelvic organ prolapse and sexual dysfunction
    Kari Bø
    Department of Sports Medicine, Norwegian School of Sport Sciences, Ulleval Stadion, Oslo, Norway
    World J Urol 30:437-43. 2012
    The objectives of the present review was to present and discuss evidence for pelvic floor muscle (PFM) training on female stress urinary incontinence (SUI), pelvic organ prolapse (POP) and sexual dysfunction.
  36. ncbi Functional anatomy of the female pelvic floor
    James A Ashton-Miller
    Department of Mechanical Engineering, Biomechanics Engineering and Institute of Gerontology, G G Brown 3208, University of Michigan, Ann Arbor, MI 48109 2125, USA
    Ann N Y Acad Sci 1101:266-96. 2007
    ..3 and the pudendal nerve under strains of up to 33%, respectively. Research is needed to better identify the pathomechanics of these conditions...
  37. ncbi Effect of abdominal and pelvic floor tasks on muscle activity, abdominal pressure and bladder neck
    Baerbel Junginger
    NHMRC Centre of Clinical Research Excellence in Spinal Pain, Injury and Health, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Queensland, Australia
    Int Urogynecol J 21:69-77. 2010
    Although the bladder neck is elevated during a pelvic floor muscle (PFM) contraction, it descends during straining...
  38. ncbi Pelvic floor muscle strength and thickness in continent and incontinent nulliparous pregnant women
    Siv Mørkved
    Department of Community Medicine and General Practice, Norwegian University of Science and Technology, 7489 Trondheim, Norway
    Int Urogynecol J Pelvic Floor Dysfunct 15:384-9; discussion 390. 2004
    The aim of the study was to measure pelvic floor muscle function in continent and incontinent nulliparous pregnant women. The study group consisted of 103 nulliparous pregnant women at 20 weeks of pregnancy...
  39. ncbi Anatomy of pelvic floor dysfunction
    Marlene M Corton
    Division of Female Pelvic Medicine and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9032, USA
    Obstet Gynecol Clin North Am 36:401-19. 2009
    ..of the pelvic organs depends on the anatomic integrity and proper interaction among the pelvic structures, the pelvic floor support components, and the nervous system...
  40. ncbi Histotopographic study of the rectourethralis muscle
    Andrea Porzionato
    Department of Human Anatomy and Physiology, Section of Anatomy, University of Padua, Italy
    Clin Anat 18:510-7. 2005
    ..These structural associations suggest a functional cooperation between the two muscles, particularly in determining the anorectal flexure...
  41. ncbi Conservative prevention and management of pelvic organ prolapse in women
    Suzanne Hagen
    Nursing, Midwifery and Allied Health Professions Research Unit, Glasgow Caledonian University, Glasgow, UK, G4 0BA
    Cochrane Database Syst Rev 12:CD003882. 2011
    ..Women with prolapse can experience a variety of pelvic floor symptoms. Treatments include surgery, mechanical devices and conservative management...
  42. ncbi Pelvic floor reconstruction using human acellular dermal matrix after cylindrical abdominoperineal resection
    Jia Gang Han
    Department of General Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People s Republic of China
    Dis Colon Rectum 53:219-23. 2010
    ..Reconstruction using a biomaterial may be a novel alternative. The purpose of this study is to report the initial results of pelvic reconstruction using human acellular dermal matrix after cylindrical abdominoperineal resection...
  43. pmc Conservative management of persistent postnatal urinary and faecal incontinence: randomised controlled trial
    C M Glazener
    Health Services Research Unit, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, AB25 2ZD
    BMJ 323:593-6. 2001
    OBJECTIVES: To assess the effect of nurse assessment with reinforcement of pelvic floor muscle training exercises and bladder training compared with standard management among women with persistent incontinence three months postnatally...
  44. ncbi Prevalence of pelvic floor disorders in the female population and the impact of age, mode of delivery, and parity
    Ilknur Kepenekci
    Department of General Surgery, Ankara University School of Medicine, Ankara, Turkey
    Dis Colon Rectum 54:85-94. 2011
    Dysfunction of pelvic floor may cause many different symptoms, such as urinary and anal incontinence, obstructed defecation and constipation. No previous studies have examined all of these symptoms together...
  45. ncbi Pelvic floor muscle training during pregnancy to prevent urinary incontinence: a single-blind randomized controlled trial
    Siv Mørkved
    Department of Community Medicine and General Practice, Norwegian University of Science and Technology, Trondheim, Norway
    Obstet Gynecol 101:313-9. 2003
    ..Pregnancy and vaginal delivery are main risk factors in the development of urinary incontinence. The aim of this study was to assess whether intensive pelvic floor muscle training during pregnancy could prevent urinary incontinence.
  46. ncbi Pelvic floor trauma in childbirth - myth or reality?
    H P Dietz
    University of Sydney, Western Clinical School, Penrith, New South Wales, Australia
    Aust N Z J Obstet Gynaecol 45:3-11. 2005
    The issue of traumatic damage to the pelvic floor in childbirth is attracting more and more attention amongst obstetric caregivers and laypersons alike...
  47. ncbi Three-dimensional magnetic resonance imaging assessment of levator ani morphologic features in different grades of prolapse
    Kavita Singh
    Department of Obstetrics and Gynecology, Royal Free and University College Medical School, London, United Kingdom
    Am J Obstet Gynecol 188:910-5. 2003
    ....
  48. ncbi Long-term study on the effects of visual biofeedback and muscle training as a therapeutic modality in pelvic floor dyssynergia and slow-transit constipation
    Edda Battaglia
    Servizio di Endoscopia e Motilità Intestinale, Cattedra di Medicina Interna, Dipartimento di Fisiopatologia Clinica, Universita di Torino, Torino, Italy
    Dis Colon Rectum 47:90-5. 2004
    Biofeedback training has been shown as an effective therapeutic measure in patients with pelvic floor dyssynergia, at least in the short term. Long-term effects have received less attention...
  49. pmc Interrater reliability and physical examination of the pubovisceral portion of the levator ani muscle, validity comparisons using MR imaging
    Rohna Kearney
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Neurourol Urodyn 25:50-4. 2006
    ..This study aims to determine interrater reliability of physical examination in detecting these defects, and to validate findings from physical examination using comparisons with MR images...
  50. ncbi Constipation: a potential cause of pelvic floor damage?
    C Amselem
    Pelvic Floor Institute, Barcelona, Spain
    Neurogastroenterol Motil 22:150-3, e48. 2010
    b>Pelvic floor damage is a major clinical problem usually attributed to obstetric injury...
  51. ncbi Vitamin D and pelvic floor disorders in women: results from the National Health and Nutrition Examination Survey
    Samuel S Badalian
    Department of Obstetrics and Gynecology, SUNY Upstate Medical University, and Gynecology and Urogynecology Center, St Joseph s Hospital Health Center, Syracuse, New York 13203, USA
    Obstet Gynecol 115:795-803. 2010
    To estimate the prevalence of vitamin D deficiency in women with pelvic floor disorders and to evaluate possible associations between vitamin D levels and pelvic floor disorders.
  52. ncbi Intrapartum risk factors for levator trauma
    K L Shek
    Nepean Clinical School, University of Sydney, Nepean Hospital, Sydney, NSW 2750, Australia
    BJOG 117:1485-92. 2010
    ..To determine intrapartum risk factors associated with levator trauma as identified by ultrasound imaging...
  53. ncbi Levator avulsion using a tomographic ultrasound and magnetic resonance-based model
    Rong R Zhuang
    Department of Obstetrics and Gynecology, Fujian Medical University, Fuzhou, Fujian, China
    Am J Obstet Gynecol 205:232.e1-8. 2011
    Delivery-related levator avulsion can cause pelvic floor dysfunction. We compared agreement between tomographic ultrasound and magnetic resonance-based models for the detection of levator defects.
  54. ncbi Behavioral therapy with or without biofeedback and pelvic floor electrical stimulation for persistent postprostatectomy incontinence: a randomized controlled trial
    Patricia S Goode
    Department of Veterans Affairs, Birmingham Atlanta Geriatric Research, Education, and Clinical Center, Atlanta, Georgia, USA
    JAMA 305:151-9. 2011
    ..Although behavioral therapy has been shown to improve postoperative recovery of continence, there have been no controlled trials of behavioral therapy for postprostatectomy incontinence persisting more than 1 year...
  55. ncbi Measurements of pelvic floor dyssynergia: which test result matters?
    Liliana Bordeianou
    Division of Gastrointestinal Surgery, Pelvic Floor Disorders Service, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Dis Colon Rectum 54:60-5. 2011
    ..and abnormal relaxation of anal sphincter on electromyographic testing are frequently used to diagnose pelvic floor dyssynergia...
  56. ncbi Pelvic floor ultrasound in prolapse: what's in it for the surgeon?
    Hans Peter Dietz
    Sydney Medical School Nepean, Nepean Hospital, Penrith, NSW, 2750, Australia
    Int Urogynecol J 22:1221-32. 2011
    ..I will also try and give a perspective for the next 5 years, to consider how imaging may transform the way we deal with pelvic floor disorders.
  57. ncbi Size of the urogenital hiatus in the levator ani muscles in normal women and women with pelvic organ prolapse
    J O DeLancey
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor 48109 0216, USA
    Obstet Gynecol 91:364-8. 1998
    ..Compare urogenital hiatus size in normal women and women with pelvic organ prolapse...
  58. ncbi Pelvic floor function in nulliparous women using three-dimensional ultrasound and magnetic resonance imaging
    J A Kruger
    Department of Sport and Exercise Science, University of Auckland, Auckland, New Zealand
    Obstet Gynecol 111:631-8. 2008
    To compare biometric measures of pelvic floor function obtained using three-dimensional (3D) ultrasound and magnetic resonance imaging (MRI) in a group of nulliparous asymptomatic young women.
  59. ncbi Comparison of pelvic floor muscle training, electromyography biofeedback, and neuromuscular electrical stimulation for bladder dysfunction in people with multiple sclerosis: a randomized pilot study
    D McClurg
    Health and Rehabilitation Sciences Research Institute, University of Ulster, Newtownabbey, Northern Ireland
    Neurourol Urodyn 25:337-48. 2006
    Bladder dysfunction affects up to 90% of the multiple sclerosis (MS) population. Interventions such as Pelvic Floor Training and Advice (PFTA), Electromyography (EMG) Biofeedback, and Neuromuscular Electrical Stimulation (NMES) have ..
  60. ncbi Management of iatrogenic foreign bodies of the bladder and urethra following pelvic floor surgery
    Tara L Frenkl
    Glickman Urologic and Kidney Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Neurourol Urodyn 27:491-5. 2008
    ..We present our recent experience with the removal of iatrogenic foreign bodies from the bladder and urethra and propose a treatment algorithm...
  61. ncbi Systematic review and economic modelling of the effectiveness and cost-effectiveness of non-surgical treatments for women with stress urinary incontinence
    M Imamura
    Health Services Research Unit, University of Aberdeen, UK
    Health Technol Assess 14:1-188, iii-iv. 2010
    ..To assess the clinical effectiveness and cost-effectiveness of non-surgical treatments for women with stress urinary incontinence (SUI) through systematic review and economic modelling...
  62. ncbi Evaluation of female pelvic-floor muscle function and strength
    Kari Bø
    Norwegian University of Sport and Physical Education, PO Box 4014, Ulleval Stadion, 0806 Oslo, Norway
    Phys Ther 85:269-82. 2005
    ..Imaging techniques may become important clinical tools in future physical therapist practice and research to measure both pathophysiology and impairment of PFM dysfunction...
  63. ncbi Risk factors associated with pelvic floor disorders in women undergoing surgical repair
    Pamela A Moalli
    Department of Obstetrics, Gynecology, and Research, Magee Womens Hospital, Magee Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Obstet Gynecol 101:869-74. 2003
    To identify demographic, obstetric, and gynecologic risk factors associated with the development of pelvic floor disorders in women who undergo surgical correction.
  64. ncbi The prevalence of major abnormalities of the levator ani in urogynaecological patients
    H P Dietz
    University of Sydney, Western Clinical School, Penrith, Australia, and Erasmus Medical Centre, Rotterdam, The Netherlands
    BJOG 113:225-30. 2006
    ..This study was designed to define prevalence and clinical significance of such abnormalities in urogynaecological patients...
  65. pmc Childbirth and pelvic floor dysfunction: an epidemiologic approach to the assessment of prevention opportunities at delivery
    Divya A Patel
    OB GYN Health Services Research Group, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, USA
    Am J Obstet Gynecol 195:23-8. 2006
    Female pelvic floor dysfunction is integral to the woman's role in the reproductive process, largely because of the unique anatomic features that facilitate vaginal birth and also because of the trauma that can occur during that event...
  66. ncbi Pelvic floor muscle activity in different sitting postures in continent and incontinent women
    Ruth R Sapsford
    Department of Physiotherapy, Mater Health Services, Brisbane, Australia
    Arch Phys Med Rehabil 89:1741-7. 2008
    To determine whether resting activity of the pelvic floor muscles (PFMs) and abdominal muscles varied in different sitting postures in parous women with and without stress urinary incontinence (SUI).
  67. ncbi Neurogenic colorectal and pelvic floor dysfunction
    Klaus Krogh
    Neurogastroenterology Unit, Department of Hepatology and Gastroenterology V, Aarhus University Hospital, Norrebrogade 2, 8000 Aarhus C, Denmark
    Best Pract Res Clin Gastroenterol 23:531-43. 2009
    ..For patients with severe symptoms trans-anal irrigation, the Malone appendicostomy or a colostomy can be recommended...
  68. ncbi Morphologies of the interfaces between the levator ani muscle and pelvic viscera, with special reference to muscle insertion into the anorectum in elderly Japanese
    Takashi Arakawa
    Department of Surgery Omori, Division of General and Gastroenterological Surgery, Toho University School of Medicine, 5 21 16 Oomori nishi, Oota ku, Tokyo 143 8540, Japan
    Anat Sci Int 79:72-81. 2004
    ..pelvic connective tissue-like smooth muscles play an important role as an autonomic buffer and/or modulator of pelvic floor function...
  69. ncbi Comparative histological study of levels 1-3 supportive tissues using pelvic floor semiserial sections from elderly nulliparous and multiparous women
    Eiji Hirata
    Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    J Obstet Gynaecol Res 37:13-23. 2011
    ..We examined whether or not the USCT changes its histological architecture by vaginal delivery in correlation with the levels 2 and 3 supportive tissues...
  70. pmc The standardization of terminology for researchers in female pelvic floor disorders
    A M Weber
    Center for Population Research, National Institute of Child Health and Human Development, Bethesda, MD 20892, USA
    Int Urogynecol J Pelvic Floor Dysfunct 12:178-86. 2001
    The lack of standardized terminology in pelvic floor disorders (pelvic organ prolapse, urinary incontinence, and fecal incontinence) is a major obstacle to performing and interpreting research...
  71. ncbi Parity, mode of delivery, and pelvic floor disorders
    Emily S Lukacz
    Women s Pelvic Medicine Center, University of California, San Diego, La Jolla, California 92037, USA
    Obstet Gynecol 107:1253-60. 2006
    This study aimed to assess the associations between parity, mode of delivery, and pelvic floor disorders.
  72. ncbi Pelvic floor dysfunction and radical hysterectomy
    K S Jackson
    Northern Gynaecological Oncology Centre, Queen Elizabeth Hospital, Gateshead NE9 6SX, United Kingdom
    Int J Gynecol Cancer 16:354-63. 2006
    ..This review presents an overview of the surgical mechanisms presumed to be responsible for pelvic floor denervation and describes subsequent bladder and bowel dysfunction, together with future possibilities for ..
  73. ncbi Childbirth and pelvic floor trauma
    H P Dietz
    Nepean Campus, Western Clinical School, University of Sydney, Penrith, Australia
    Best Pract Res Clin Obstet Gynaecol 19:913-24. 2005
    The issue of traumatic damage to the pelvic floor in childbirth is attracting more and more attention amongst obstetric caregivers and laypersons alike...
  74. ncbi Totally robotic surgery for rectal cancer: from splenic flexure to pelvic floor in one setup
    Yoon Ah Park
    Department of Surgery, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun gu, 120 752 Seoul, Korea
    Surg Endosc 24:715-20. 2010
    ..However, totally robotic surgery for rectal cancer is still technically challenging. This report describes the technical details and outcomes of totally robotic rectal surgery...
  75. ncbi Psychometric evaluation of 2 comprehensive condition-specific quality of life instruments for women with pelvic floor disorders
    M D Barber
    Division of Gynecologic Specialties, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, USA
    Am J Obstet Gynecol 185:1388-95. 2001
    OBJECTIVE: To evaluate the psychometric properties of the Pelvic Floor Distress Inventory (PFDI) and the Pelvic Floor Impact Questionnaire (PFIQ)...
  76. ncbi Role of static and dynamic MR imaging in surgical pelvic floor dysfunction
    Lousine Boyadzhyan
    Departments of Radiology and Urology, University of California Los Angeles David Geffen School of Medicine, 10833 Le Conte Ave, Los Angeles, CA 90095 1721, USA
    Radiographics 28:949-67. 2008
    b>Pelvic floor dysfunction (PFD) is a hidden women's health epidemic in the United States, with over 10% of women having a lifetime risk for undergoing a surgical repair for this problem...
  77. pmc Significant linkage evidence for a predisposition gene for pelvic floor disorders on chromosome 9q21
    Kristina Allen-Brady
    Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT 84105, USA
    Am J Hum Genet 84:678-82. 2009
    Predisposition factors for pelvic floor disorders (PFDs), including pelvic organ prolapse (POP), stress urinary incontinence (SUI), urge urinary incontinence (UUI), and hernias, are not well understood...
  78. ncbi The effects of birth on urinary continence mechanisms and other pelvic-floor characteristics
    S Meyer
    Gynecology Obstetrics Department, CHUV, Lausanne, Switzerland
    Obstet Gynecol 92:613-8. 1998
    ..To determine the effects of delivery on bladder and anorectal functions...
  79. ncbi The prevalence and factors associated with previous surgery for pelvic organ prolapse and/or urinary incontinence in a cross-sectional study in The Netherlands
    T A de Boer
    Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, The Netherlands
    Eur J Obstet Gynecol Reprod Biol 158:343-9. 2011
    ..To estimate the prevalence and identify the factors associated with previous pelvic organ prolapse (POP) and/or incontinence surgery...
  80. ncbi Three-dimensional ultrasound imaging of the pelvic floor: the effect of parturition on paravaginal support structures
    H P Dietz
    Royal Hospital for Women, Sydney, Australia
    Ultrasound Obstet Gynecol 21:589-95. 2003
    ..This study used three-dimensional translabial ultrasound to assess these structures and document peripartal changes...
  81. ncbi Systematic review of randomized controlled trials of the effectiveness of biofeedback for pelvic floor dysfunction
    C E Koh
    Surgical Outcomes Research Centre SOURCE, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
    Br J Surg 95:1079-87. 2008
    b>Pelvic floor dysfunction (PFD) is a type of functional constipation. The effectiveness of biofeedback as a treatment remains unclear.
  82. ncbi Pelvic floor muscle training for prevention and treatment of urinary and faecal incontinence in antenatal and postnatal women
    Rhianon Boyle
    Academic Urology Unit, University of Aberdeen, Aberdeen, UK
    Cochrane Database Syst Rev 10:CD007471. 2012
    About a third of women have urinary incontinence and up to a 10th have faecal incontinence after childbirth. Pelvic floor muscle training is commonly recommended during pregnancy and after birth both for prevention and the treatment of ..
  83. ncbi The role of pelvic floor dysfunction and slow colonic transit in adolescents with refractory constipation
    Denesh K Chitkara
    Clinical Enteric Neuroscience Translational and Epidemiological Research C E N T E R Program and Department of Pediatrics, Mayo Clinic, Rochester, Minnesota, USA
    Am J Gastroenterol 99:1579-84. 2004
    Although pelvic floor dysfunction (PFD) is recognized as a cause of refractory constipation in adults, this diagnosis is not frequently considered in children and adolescents with refractory constipation...
  84. ncbi Is there a long-lasting effect of pelvic floor muscle training in women with urinary incontinence after ischemic stroke? A 6-month follow-up study
    S Tibaek
    Department of Geriatrics and Rheumatology, Copenhagen University Hospital, Glostrup, Nordre Ringvej, Glostrup, 2600, Denmark
    Int Urogynecol J Pelvic Floor Dysfunct 18:281-7. 2007
    The aim of this study was to evaluate the long-lasting effect of pelvic floor muscle training (PFMT) in women with urinary incontinence after stroke measured by quality of life parameters...
  85. ncbi Searching for pelvic floor muscle exercises on YouTube: what individuals may find and where this might fit with health service programmes to promote continence
    Kate Stephen
    University of the Highlands and Islands, Ness Walk, Inverness, UK
    Menopause Int 18:110-5. 2012
    This paper describes the investigation, categorization/characterization and viewing of pelvic floor muscle exercises (PFME) on YouTube from the perspective of the 'wisdom of the crowd'...
  86. ncbi Monosynaptic projections from the nucleus retroambiguus to motoneurons supplying the abdominal wall, axial, hindlimb, and pelvic floor muscles in the female rhesus monkey
    V G VanderHorst
    Department of Anatomy, University California San Francisco, San Francisco, California 94143, USA
    J Comp Neurol 424:233-50. 2000
    ..same seven monkeys also received cholera toxin subunit b (CTb) injections into different hindlimb, axial, and pelvic floor muscles...
  87. pmc Coexistence of constipation and incontinence in children and adults
    S Nurko
    Center for Motility and Functional Gastrointestinal Disorders, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, United States
    Best Pract Res Clin Gastroenterol 25:29-41. 2011
    ..in children and adults, it is thought to be secondary to overflow, while in adults it may also be related to pelvic floor dysfunction and denervation...
  88. ncbi Factors associated with PISQ-12 completion in an academic urogynecology population
    Sarah A Collins
    Department of Obstetrics and Gynecology, Division of Urogynecology, Hartford Hospital, Hartford, CT 06106, USA
    Int Urogynecol J 21:579-82. 2010
    ..This study compared sexually active (SA) and non-sexually active (NSA) women who complete the PISQ-12, hypothesizing that these groups differ substantially...
  89. ncbi Mid-trimester serum relaxin concentrations and post-partum pelvic floor dysfunction
    Marie Andrée Harvey
    Department of Obstetrics and Gynecology, Division of Urogynecology and Pelvic Floor Reconstruction, Kingston General Hospital, and Queen s University, Kingston, Ontario, Canada
    Acta Obstet Gynecol Scand 87:1315-21. 2008
    To compare mid-trimester serum relaxin concentration (SRC) in primiparous women with or without pelvic floor dysfunction (PFD--stress urinary incontinence (SUI), genital prolapse).
  90. pmc Protocol for translabial 3D-ultrasonography for diagnosing levator defects (TRUDIL): a multicentre cohort study for estimating the diagnostic accuracy of translabial 3D-ultrasonography of the pelvic floor as compared to MR imaging
    Kim J B Notten
    Department of Obstetrics and Gynecology, Maastricht University Medical Centre, The Netherlands
    BMC Womens Health 11:23. 2011
    ..Levator ani defects can be imaged with MRI and also with Translabial 3D ultrasonography of the pelvic floor. The primary aim of this study is to assess the diagnostic accuracy of translabial 3D ultrasonography for ..
  91. ncbi An initial evaluation of pelvic floor function and quality of life of bladder exstrophy patients after ureterosigmoidostomy
    Jennifer Miles-Thomas
    James Buchanan Brady Urological Institute, Division of Pediatric Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Gastrointest Surg 10:473-7. 2006
    Classic bladder exstrophy is characterized by displaced pelvic floor musculature and significant skeletal and genitourinary defects...
  92. ncbi [Pelvic floor disorders]
    Gloria Lacima
    Unidad Motilidad Digestiva, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, Barcelona, Espana
    Gastroenterol Hepatol 31:587-95. 2008
    ..The most important risk factors for pelvic floor disorders are vaginal delivery and chronic constipation...
  93. ncbi The effect of pelvic floor muscle exercise on women with chronic non-specific low back pain
    Mohammad A Mohseni-Bandpei
    Physiotherapy Department, University of Social Welfare and Rehabilitation Sciences, PO Box 1985713834, Evin, Tehran, Iran
    J Bodyw Mov Ther 15:75-81. 2011
    ..It is thought that a large number of muscles have a role in spinal stability including the pelvic floor muscle (PFM)...
  94. ncbi Relationship between the integrity of the pelvic floor muscles and early recovery of continence after radical prostatectomy
    Cheryn Song
    Department of Urology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    J Urol 178:208-11. 2007
    We investigated how the preoperatively estimated integrity of pelvic floor muscles related to the recovery of continence after radical prostatectomy.
  95. pmc Feasibility of diffusion tensor imaging (DTI) with fibre tractography of the normal female pelvic floor
    F M Zijta
    Department of Radiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Eur Radiol 21:1243-9. 2011
    To prospectively determine the feasibility of diffusion tensor imaging (DTI) with fibre tractography as a tool for the three-dimensional (3D) visualisation of normal pelvic floor anatomy.
  96. ncbi Conservative and behavioural management of constipation
    W E Whitehead
    Center for Functional GI and Motility Disorders, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7080, USA
    Neurogastroenterol Motil 21:55-61. 2009
    ....
  97. ncbi Sectional neuroanatomy of the pelvic floor
    Joseph S Kass
    Department of Neurology, Baylor College of Medicine, University of Texas School of Medicine, Houston, TX, USA
    J Comput Assist Tomogr 34:473-7. 2010
    ..innervations of the pelvis that can be used to interpret magnetic resonance images of muscles and nerves in the pelvic floor region...
  98. ncbi Repair of vaginal vault prolapse and pelvic floor relaxation using polypropylene mesh
    Matthew P Rutman
    Department of Urology, Columbia University School of Medicine, New York, New York, USA
    Neurourol Urodyn 24:654-8. 2005
    ..Existing transvaginal procedures do not address pelvic floor descent...
  99. ncbi Effects of combined pelvic floor muscle exercise and a support group on urinary incontinence and quality of life of postprostatectomy patients
    Amy Y Zhang
    Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, USA
    Oncol Nurs Forum 34:47-53. 2007
    To examine the effect of combined pelvic floor muscle exercise (PFME) and a support group on postprostatectomy urinary incontinence and quality of life.
  100. ncbi Dynamic MR imaging of the pelvic floor performed with patient sitting in an open-magnet unit versus with patient supine in a closed-magnet unit
    Katharina M Bertschinger
    Institute of Diagnostic Radiology, University Hospital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Radiology 223:501-8. 2002
    To compare open-magnet magnetic resonance (MR) imaging performed with the patient sitting with dynamic closed-magnet MR imaging of the pelvic floor performed with the patient supine.
  101. ncbi Predictors of intention to adhere to physiotherapy among women with urinary incontinence
    D Alewijnse
    Departments of Health Education and Health Promotion and General Practice, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Health Educ Res 16:173-86. 2001
    During the last decade, pelvic floor muscle exercise (PFME) therapy has proved its short-term efficacy among women with urinary incontinence. Long-term success with PFME therapy is hampered by non-adherence...

Research Grants73

  1. Stem Cell Homing for Treatment of Female Pelvic Floor Disorders
    Margot S Damaser; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Up to half the women in the U.S. experience female pelvic floor disorders (FPFD): stress urinary incontinence (SUI), fecal incontinence, and pelvic organ prolapse (POP)...
  2. Genetics of Spontaneous Pelvic Organ Prolapse in the Mouse
    Jay E Reeder; Fiscal Year: 2010
    ..The lifetime risk of undergoing surgery for pelvic floor disorders exceeds 11% by age eighty, and prolapse is the most common indication for hysterectomy in women over ..
  3. Tissue recovery in the pathophysiology of stress urinary incontinence
    Adonis K Hijaz; Fiscal Year: 2013
    ..Vaginal delivery results in injury to the pelvic floor and continence mechanism;however, injury alone does not explain the entire picture on the pathophysiological ..
  4. Regenerative Adjuvant Therapy for Stress Urinary Incontinence
    Margot S Damaser; Fiscal Year: 2011
    ..The only rehabilitation method for the maternal injuries of childbirth is pelvic floor (Kegel) exercises which strengthen the muscles of the pelvic floor and prevent leakage between voids...
  5. Mid Career Award in Patient Oriented Pelvic Floor Research
    Holly E Richter; Fiscal Year: 2013
    ..competitive renewal of Dr Richter's Mid-Career Investigator Award in Patient Oriented Research in Female Pelvic Floor Disorders is to provide Holly E...
  6. Improving Urinary Continence and Quality of Life in Prostate Cancer Patients
    Amy Y Zhang; Fiscal Year: 2012
    ..Although evidence suggests that pelvic floor muscle exercises (PFME), combined with biofeedback training, significantly improves continence in the early ..
  7. Behavioral therapy to treat urinary symptoms in Parkinson's disease
    ELIZABETH CAMILLE VAUGHAN; Fiscal Year: 2012
    ..Meanwhile, behavioral interventions for UI - including pelvic floor muscle exercise (PFME) therapy - have proven efficacy in randomized controlled trials and are free of side ..
  8. Pelvic Floor Disorders Network - Duke University Clinical Site
    Anthony G Visco; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Pelvic floor disorders research at Duke University Medical Center (DUMC) is sophisticated and comprehensive with committed investigators addressing issues of great importance to women...
  9. Pittsburgh Pelvic Floor Research Program
    Halina M Zyczynski; Fiscal Year: 2013
    ..the capabilities of the University of Pittsburgh to participate as a clinical site in the NICHD-sponsored Pelvic Floor Disorders Network (PFDN)...
  10. Architectural Design of the Pelvic Floor Skeletal Muscles
    Marianna Alperin; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Pelvic floor disorders (PFD) include pelvic organ prolapse (POP), urinary incontinence, and fecal incontinence...
  11. Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)
    Karl J Kreder; Fiscal Year: 2013
    ..g. bladder, urethra, vagina, prostate and/or pelvic floor muscle dysfunction), we hypothesize that many patients have central or systemic pathophysiologic processes ..
  12. Novel Pelvic Floor Pain Measures to Enhance Female Pelvic Pain Evaluation
    FRANK FU SHENG TU; Fiscal Year: 2012
    ..observational study of one important but understudied aspect of PBS and related pelvic pain syndromes: pelvic floor pain dysfunction...
  13. Patient-Reported Outcomes in Functioning for Female Pelvic Floor Disorders
    Vivian W Sung; Fiscal Year: 2013
    ..is to improve the quality of patient-reported outcome measures (PROs) and ultimately patient care in female pelvic floor disorders (PFDs)...
  14. Elastic Fiber Homeostasis in the Vaginal Wall
    Hiromi Yanagisawa; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Pelvic floor disorders affect up to one-third of adult women...
  15. Physical Activity and Pelvic Floor Disorders
    Ingrid E Nygaard; Fiscal Year: 2012
    ..Understanding how physical activity impacts pelvic floor disorders is important: half of American women have urinary incontinence or pelvic organ prolapse and one in ..
  16. Regeneration of the Pelvic and Urethral Supports by Muscle Derived Stem Cells
    Matthew Ho; Fiscal Year: 2009
    ..SUI is a common condition with significant morbidity, and treatment options include pelvic floor exercises, pharmacological treatment, and surgery...
  17. Core-Shell Fiber Mesh for the Treatment of UI and PFD in Elderly Women
    MICHAEL P H LAU; Fiscal Year: 2011
    ..fibers to controllably contract and provide support to pelvic organs with the long term goal of correcting pelvic floor disorders (PFDs) in elderly women...
  18. Translating Unique Learning for Incontinence Prevention: The TULIP Project
    Janis M Miller; Fiscal Year: 2013
    ..A key committee of the 2008 International Consultation on Incontinence concluded that pelvic floor muscle training (PFMT) should be offered as first line therapy to all women with stress, urge, or mixed UI and ..
  19. Brown/WIH Pelvic Floor Disorders Network Site
    Vivian W Sung; Fiscal Year: 2013
    ..applicant): The mission of the PFDN is to identify optimal diagnosis and management strategies for women with pelvic floor disorders (PFDs) and this is directly in line with Women and Infants Hospital (WIH)/Brown's mission and ..
  20. Development & Psychometric Evaluation of the ICIQ-B
    ALAYNE DENISE MARKLAND; Fiscal Year: 2011
    ..modular questionnaires for men and women for the diagnosis and measurement of a variety of urinary, bowel, and pelvic floor disorders in research and clinical practice...
  21. Cesarean and vaginal birth: cohort study of the impact on pelvic floor disorders
    VICTORIA LYNN HANDA; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Despite the very high prevalence of female pelvic floor disorders (urinary incontinence, fecal incontinence, and pelvic organ prolapse), the biological mechanisms underlying these disorders are ..
  22. Vaginal Tactile Imager for Pelvic Floor Biomechanical Assessment
    Vladimir Egorov; Fiscal Year: 2013
    ..a device entitled Vaginal Tactile Imager (VTI) for 3-D visualization and assessment of mechanical properties of pelvic floor tissues...
  23. Conservative Treatment of Fecal Incontinence in the Elderly: Effectiveness T
    William E Whitehead; Fiscal Year: 2013
    ..The treatment includes patient education about the physiology of how continence is maintained, pelvic floor exercises, behavioral strategies for preventing FI, and use of fiber or nonprescription medication to treat ..
  24. MECHANISMS OF INCONTINENCE FOLLOWING VAGINAL DISTENSION
    Margot S Damaser; Fiscal Year: 2010
    ..by applicant): Clinically, during vaginal delivery of children, the tissues, muscles, and organs of the pelvic floor are compressed and injured...
  25. Vitamin D Supplementation in Older Adults with Urinary Incontinence
    ALAYNE DENISE MARKLAND; Fiscal Year: 2013
    ..potential mechanisms that may contribute to improved UI symptoms in a subgroup of women, including increased pelvic floor skeletal muscle strength, decreased detrusor muscle over activity, improved mobility, and inflammatory urinary ..
  26. 3T Pelvic MRI Measures After Childbirth: Pre-Pregnancy and 6 Months Postpartum (R
    Holly E Richter; Fiscal Year: 2010
    ..imaging (MRI) studies have been performed in nulliparous women to define the range of normal variability of pelvic floor anatomic findings with comparison to their postpartum MRI findings and symptoms...
  27. Decision-making in Pelvic Floor Disorders: Translating Outcomes to Practice
    JAMES LEIGH WHITESIDE; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Pelvic floor disorders include a broad-range of health conditions that primarily affect women. These include bladder and bowel problems as well as problems of vaginal support...
  28. Pelvic Floor Disorders Network Data Coordinating Center (U01)
    Dennis D Wallace; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): RTl proposes to serve as the data coordinating center (DCC) for the NICHD Pelvic Floor Disorders Network (PFDN), in support of its mission to improve the care of women with pelvic floor disorders (..
  29. Pelvic floor Disorders Network-Data Coordinating Center
    CATHERINE A SPINO; Fiscal Year: 2010
    b>Pelvic floor disorders, such as urinary incontinence, pelvic organ prolapse, and fecal incontinence, are common and significant health-related problems for women in the United States...
  30. The Urethral Sleeve Sensor_A Novel Method of Measuring Urethral Pressure
    CHARLES WILLIAM NAGER; Fiscal Year: 2012
    ..Our secondary aim will be to understand the mechanism of pelvic floor contraction for improving urinary continence by correlating vaginal pressure measurements obtained during ..
  31. Combined Behavioral and Drug Treatment of Overactive Bladder in Men
    KATHRYN LARSEN BURGIO; Fiscal Year: 2013
    ..therapies (primarily alpha- blocking agents and/or antimuscarinic agents) or behavioral treatment (pelvic floor muscle training, urge suppression, delayed voiding)...
  32. Self-Care to Prevent Birth-Related UI in Diverse Women
    Lisa Kane Low; Fiscal Year: 2012
    Project Abstract SELF-CARE TO PREVENT BIRTH-RELATED UI IN DIVERSE WOMEN Despite compelling evidence that pelvic floor muscle training (PFMT) reduces childbearing women's risk of urinary incontinence (UI) by up to 39-59% 1;2;3, too ..
  33. MOLECULAR AND BIOCHEMICAL STUDY OF COLLAGEN IN PROLAPSE
    Anthony Visco; Fiscal Year: 2002
    DESCRIPTION (Adapted from Applicant's Description): Pelvic floor dysfunction including urinary incontinence and pelvic organ prolapse is a major health issue for women resulting in an 11 percent lifetime risk of requiring surgery...
  34. Pelvic Floor Disorders Network Clinical Sites (U10)
    Lily A Arya; Fiscal Year: 2013
    ..The goal of this application is to competitively identify clinical sites to conduct clinical trials for female pelvic floor disorders...
  35. University of Michigan WRHR Career Development Program
    TIMOTHY RB JOHNSON; Fiscal Year: 2013
    ..We aim to target programmatic content in specific areas of pelvic floor and urogynecology research, reproductive science biology, and reproductive and perinatal genetics, where ..
  36. Protease regulation and integrity of connective tissues of the pelvic floor
    Hiromi Yanagisawa; Fiscal Year: 2013
    ..The specific impact of childbirth, aging, and menopause on the supportive structures of the pelvic floor, however, is not known...
  37. Development of Wireless Abdominal Pressure Senor for Pelvic Floor Research
    Ingrid E Nygaard; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Pelvic floor disorders affect one in four American women. Few modifiable risk factors have been identified that might reduce the incidence or progression of pelvic floor disorders...
  38. Perioperative Pelvic Floor Rehab: A Rrandomized Trial
    Holly E Richter; Fiscal Year: 2013
    ..of Alabama at Birmingham (UAB) is seeking to successfully compete in the third cycle of the NICHD sponsored Pelvic Floor Disorders Network...
  39. Website for Self-Management of Fecal Incontinence
    William E Whitehead; Fiscal Year: 2013
    ..Our team has developed a conservative treatment protocol involving patient education, pelvic floor exercises, and normalization of stool consistency with fiber or medication which reduces FI episode frequency ..
  40. Minimally Invasive Vaginal Prolapse Repair
    WALTER VON PECHMANN; Fiscal Year: 2012
    ..to facilitate a minimally invasive repair for uterine or vaginal vault prolapsed, a disorder of the female pelvic floor. The current gold standard operation for this disorder is the sacral colpopexy, primarily performed via ..
  41. Group Learning Achieves Decreased Incidents of Lower Urinary Symptoms
    Carolyn M Sampselle; Fiscal Year: 2013
    ..outcome measures will assess frequency of incontinence episodes, volume of urine loss, type of incontinence, pelvic floor muscle strength, patient satisfaction, patient perception of improvement, impact on quality of life, and cost-..
  42. Clinical and Translational Resaerch in the Pelvic Floor Disorders Network
    Linda Brubaker; Fiscal Year: 2013
    ..by applicant): This application proposes work that advances the clinical and translational science of female pelvic floor disorders by continuing collaboration within the Pelvic Floor Disorders Network...
  43. Tailored Outcomes for Female Urinary Incontinence
    Vivian W Sung; Fiscal Year: 2012
    ..and assess differential item functioning across demographic variables, UI severity and type, and co-existing pelvic floor disorders...
  44. Case Urology Translational Research Training Program (CUTRTP)
    Firouz Daneshgari; Fiscal Year: 2013
    ..to focus on translational urology research in 3 main areas: a) genitourinary cancers, b) female pelvic floor disorders, and c) urological complications of obesity and diabetes...
  45. Urinary Metabolites in IC PBS Diagnosis
    JAYOUNG NONE KIM; Fiscal Year: 2013
    ..and accurate means of diagnosing IC/PBS and stratifying these patients from patients with other bladder or pelvic floor conditions. We also seek in the long term to validate molecular targets for therapeutic strategies...
  46. Abdominal Colpopexy: Comparison of Endoscopic Surgical Strategies (ACCESS)
    ELIZABETH ROSE MUELLER; Fiscal Year: 2010
    ..Degree of bother from prolapse symptoms will be measured using the Pelvic Floor Distress Inventory (PFDI) Short Form questionnaire...
  47. Cleveland Clinic Clinical Site
    Matthew Barber; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The goal of the Pelvic Floor Disorders Network (PFDN) is to identify optimum diagnosis and management strategies for women with pelvic floor disorders (PFD) using the highest quality research methods ..
  48. RCT of Hypnotherapy vs Tpolterodine for OAB: Voiding and Brain Activation Changes
    REBECCA GLENN ROGERS; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The University of New Mexico (UNM) proposes to join the Pelvic Floor Disorders Network (PFDN) to achieve the Network's primary goal of conducting rigorous, multi-center clinical trials to ..
  49. IDENTIFICATION OF GENES PREDISPOSING TO PELVIC FLOOR DISORDERS
    LISA CANNON ALBRIGHT; Fiscal Year: 2013
    ..The co-PIs both have significant experience, Dr. Norton in Pelvic Floor Disorder (PFD) genetics and Dr. Cannon-Albright in predisposition gene identification...
  50. Michigan BIRCWH Career Development Program
    TIMOTHY RB JOHNSON; Fiscal Year: 2013
    ..We will target scholars'four areas of special interest: (1) pelvic floor/urogynecology research;(2) health services research;(3) reproductive science and women's medicine;and, (4) ..
  51. ANORECTAL MANIFESTATIONS OF FEMALE PELVIC FLOOR DISORDER
    Adil Bharucha; Fiscal Year: 2002
    b>Pelvic floor disorders in females include two under recognized, yet potentially devastating manifestations, fecal incontinence (FI) and obstructed defecation (OD)...
  52. Spontaneous vs. Directed Pushing: Analysis of Audiotapes of 2nd stage Labor and A
    Lisa Kane Low; Fiscal Year: 2012
    ..by applicant): Childbirth is implicated in increasing a woman's lifetime risk of experiencing adverse pelvic floor changes associated with incontinence, negatively impacting her quality of life...
  53. Improved Surgical Treatment of Pelvic Organ Prolapse
    KEITH LIPFORD; Fiscal Year: 2009
    ..of this research and development project is to improve treatment of vaginal prolapse, a disorder of the female pelvic floor. Each year, approximately 200,000 women undergo inpatient procedures related to pelvic organ prolapse in the ..
  54. Pelvic Floor Disorders Network
    CHARLES WILLIAM NAGER; Fiscal Year: 2013
    ..applicant): The objectives and aims of this application are for the San Diego site to continue its work In the Pelvic Floor Disorders Network (PFDN)...
  55. The role of DAMPS in painful bladder syndrome
    Fletcher A White; Fiscal Year: 2013
    ..Bladder pain syndrome (BPS or interstitial cystitis, IC) patients typically exhibit marked tenderness of pelvic floor musculature and that treatments directed solely at those muscles often resulted in marked improvement of ..
  56. Mobile Software for Assisting Individuals in Overcoming Urinary Incontinence
    JEFFREY A PEPPER; Fiscal Year: 2012
    ..Many interventions have been developed for overcoming UI, including pelvic floor exercises Kegels drugs dietary programs behavioral modifications, and surgical procedures...
  57. Translational Research in Pelvic Floor Disorders
    Jennifer Marie Wu; Fiscal Year: 2013
    ..independent clinician-scientist who is able to use innovative tools to identify the root causes of pelvic floor disorders and translate those findings into improved clinical practice...
  58. NICHD Pelvic Floor Disorders Network Clinical Sites (U10)
    Joseph I Schaffer; Fiscal Year: 2013
    ..Hospital and the facilities and patient population available to carry out clinical protocols sponsored by the Pelvic Floor Disorders Network (PFDN)...
  59. In Situ Biomechanical Testing of the Anterior Vaginal Support System
    Yvonne Hsu; Fiscal Year: 2010
    ..provided by applicant): This R03 proposal is in response to the RFA entitled "Translational Research in Female Pelvic Floor Disorders" which recognized the need for collaborative projects between clinicians and basic scientists to ..
  60. Pelvic Floor Disorders Network Clinical Sites
    Ingrid E Nygaard; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Pelvic floor disorders are common, bothersome, and inadequately treated...
  61. PERIOPERATIVE TELEHEALTH PROGRAM FOR POST-PROSTATECTOMY INCONTINENCE
    Patricia Goode; Fiscal Year: 2009
    ..first 6 months of this developmental study will be needed to adapt the perioperative rehabilitation protocol (pelvic floor muscle training, progressive exercises, and bladder control techniques) for telehealth administration...
  62. Iowa Pelvic Floor Disorders Clinical Trials Network
    Karl Kreder; Fiscal Year: 2005
    ..on a visual analogue scale, (3) adverse events, (4) urge incontinence specific quality of life measure, (5) pelvic floor distress inventory, (6) sexual function assessment tool, and (7) generic quality of life measure...
  63. Epidemiology and Mechanisms of Fecal Incontinence
    Adil Bharucha; Fiscal Year: 2005
    ..Our novel "fluoroscopic" single-shot fast spin-echo MRI techniques visualize pelvic floor descent during defecation in real-time...
  64. Birth, Muscle Injury and Pelvic Floor Dysfunction
    John O L Delancey; Fiscal Year: 2013
    ..Of the 3 million women who deliver vaginally each year 300,000 or 1 in 10 will later require surgery for pelvic floor dysfunction due to their unique sex-determined role in reproduction...
  65. Interstitial Cystitis Clinical Research Network
    Christopher Payne; Fiscal Year: 2007
    ..disorder or are there important clinical distinctions between IC, vulvadynia, chronic prostatitis, and pelvic floor dysfunction? The relevance of standard diagnostic tools has been challenged...
  66. MODEL FOR PELVIC FLOOR DISORDERS
    Amanda Clark; Fiscal Year: 2004
    ..Preliminary data indicate that this model system is a valid and clinically relevant one for the study of pelvic floor disorders...
  67. PARTURITION INDUCED PELVIC FLOOR NEUROPATHY
    KARL THOR; Fiscal Year: 2003
    ..Prolapse results from loss of support by pelvic floor musculature (predominantly levator ani muscles) and connective tissue...
  68. Female Pelvic Research Network Application for Support of Scientific Meeting
    Linda Brubaker; Fiscal Year: 2010
    ..The research performed by the FPRN is aimed at answering clinical questions about pelvic floor dysfunction in women, including urinary incontinence and lower urinary tract disorders...
  69. Clinical Trials Network-Female Pelvic Floor Disorders
    Dirk Kieback; Fiscal Year: 2003
    The Baylor Pelvic Floor Dysfunction Unit as part of the NICHD Clinical Trials Network will be a productive and dynamic center...
  70. Epidemiology of Female Pelvic Floor Disorders
    Kristen Kjerulff; Fiscal Year: 2001
    Female pelvic floor disorders are a significant public health problem, cause major impairments in quality of life, and impose a substantial burden on individuals and on society as a whole...
  71. Mechanisms of Female Urinary Incontinence in Diabetes
    Margot Damaser; Fiscal Year: 2006
    ..In addition, women are at increased risk of later development of stress urinary incontinence due to pelvic floor injuries sustained during vaginal delivery of children...
  72. A SYSTEM FOR MEASURING PELVIC MUSCLE STRENGTH IN WOMEN
    Neil Cole; Fiscal Year: 2000
    ..developed for directly measuring maximum voluntary isometric strength and contractile properties of the female pelvic floor muscles during hard coughs and valsalva provocation tests...
  73. Novel Applications of Sarcomere Length to Improve Anal Continence
    RAVINDER MITTAL; Fiscal Year: 2009
    ..indicate that the female patient population constitutes the fastest growing segment of VA health care users and pelvic floor disorders (fecal and urinary incontinence, pelvic organ prolapse) are extremely common in this patient ..