head

Summary

Top Publications

  1. pmc The influence of head motion on intrinsic functional connectivity MRI
    Koene R A van Dijk
    Harvard University Department of Psychology, Center for Brain Science, Cambridge, MA 02138, USA
    Neuroimage 59:431-8. 2012
  2. pmc Bioelectric signaling regulates head and organ size during planarian regeneration
    Wendy Scott Beane
    Biology Department and Tufts Center for Regenerative and Developmental Biology, Tufts University, 200 Boston Avenue, Suite 4600, Medford, MA 02155, USA
    Development 140:313-22. 2013
  3. ncbi British 1990 growth reference centiles for weight, height, body mass index and head circumference fitted by maximum penalized likelihood
    T J Cole
    MRC Dunn Nutrition Centre, Cambridge, UK
    Stat Med 17:407-29. 1998
  4. pmc The bilaterian head patterning gene six3/6 controls aboral domain development in a cnidarian
    Chiara Sinigaglia
    Sars Centre for Marine Molecular Biology, University of Bergen, Bergen, Norway
    PLoS Biol 11:e1001488. 2013
  5. pmc Impact of in-scanner head motion on multiple measures of functional connectivity: relevance for studies of neurodevelopment in youth
    Theodore D Satterthwaite
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuroimage 60:623-32. 2012
  6. ncbi Formation of the head organizer in hydra involves the canonical Wnt pathway
    Mariya Broun
    Department of Developmental and Cell Biology and the Developmental Biology Center, University of California, Irvine, CA 92697, USA
    Development 132:2907-16. 2005
  7. pmc The head-regeneration transcriptome of the planarian Schmidtea mediterranea
    Thomas Sandmann
    Division Signaling and Functional Genomics, German Cancer Research Center, Im Neuenheimer Feld 580, D 69120 Heidelberg, Germany
    Genome Biol 12:R76. 2011
  8. pmc Candidate gene screen in the red flour beetle Tribolium reveals six3 as ancient regulator of anterior median head and central complex development
    Nico Posnien
    Center for Molecular Physiology of the Brain CMPB, Göttingen Center of Molecular Biology, Caspari Haus, Georg August University Gottingen, Gottingen, Germany
    PLoS Genet 7:e1002416. 2011
  9. ncbi Smed-betacatenin-1 is required for anteroposterior blastema polarity in planarian regeneration
    Christian P Petersen
    Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA
    Science 319:327-30. 2008
  10. ncbi Genetic and environmental influences on birth weight, birth length, head circumference, and gestational age by use of population-based parent-offspring data
    Astrid Lunde
    Section for Epidemiology and Medical Statistics, Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
    Am J Epidemiol 165:734-41. 2007

Detail Information

Publications511 found, 100 shown here

  1. pmc The influence of head motion on intrinsic functional connectivity MRI
    Koene R A van Dijk
    Harvard University Department of Psychology, Center for Brain Science, Cambridge, MA 02138, USA
    Neuroimage 59:431-8. 2012
    ..A confounding factor is head motion. Children move more than adults, older adults more than younger adults, and patients more than controls...
  2. pmc Bioelectric signaling regulates head and organ size during planarian regeneration
    Wendy Scott Beane
    Biology Department and Tufts Center for Regenerative and Developmental Biology, Tufts University, 200 Boston Avenue, Suite 4600, Medford, MA 02155, USA
    Development 140:313-22. 2013
    ..Using the planarian model system, we report that membrane voltage-dependent bioelectric signaling determines both head size and organ scaling during regeneration...
  3. ncbi British 1990 growth reference centiles for weight, height, body mass index and head circumference fitted by maximum penalized likelihood
    T J Cole
    MRC Dunn Nutrition Centre, Cambridge, UK
    Stat Med 17:407-29. 1998
    To update the British growth reference, anthropometric data for weight, height, body mass index (weight/height2) and head circumference from 17 distinct surveys representative of England, Scotland and Wales (37,700 children, age range 23 ..
  4. pmc The bilaterian head patterning gene six3/6 controls aboral domain development in a cnidarian
    Chiara Sinigaglia
    Sars Centre for Marine Molecular Biology, University of Bergen, Bergen, Norway
    PLoS Biol 11:e1001488. 2013
    The origin of the bilaterian head is a fundamental question for the evolution of animal body plans. The head of bilaterians develops at the anterior end of their primary body axis and is the site where the brain is located...
  5. pmc Impact of in-scanner head motion on multiple measures of functional connectivity: relevance for studies of neurodevelopment in youth
    Theodore D Satterthwaite
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuroimage 60:623-32. 2012
    It has recently been reported (Van Dijk et al., 2011) that in-scanner head motion can have a substantial impact on MRI measurements of resting-state functional connectivity...
  6. ncbi Formation of the head organizer in hydra involves the canonical Wnt pathway
    Mariya Broun
    Department of Developmental and Cell Biology and the Developmental Biology Center, University of California, Irvine, CA 92697, USA
    Development 132:2907-16. 2005
    ..In hydra, the head organizer is located in the hypostome, the apical portion of the head...
  7. pmc The head-regeneration transcriptome of the planarian Schmidtea mediterranea
    Thomas Sandmann
    Division Signaling and Functional Genomics, German Cancer Research Center, Im Neuenheimer Feld 580, D 69120 Heidelberg, Germany
    Genome Biol 12:R76. 2011
    Planarian flatworms can regenerate their head, including a functional brain, within less than a week...
  8. pmc Candidate gene screen in the red flour beetle Tribolium reveals six3 as ancient regulator of anterior median head and central complex development
    Nico Posnien
    Center for Molecular Physiology of the Brain CMPB, Göttingen Center of Molecular Biology, Caspari Haus, Georg August University Gottingen, Gottingen, Germany
    PLoS Genet 7:e1002416. 2011
    Several highly conserved genes play a role in anterior neural plate patterning of vertebrates and in head and brain patterning of insects...
  9. ncbi Smed-betacatenin-1 is required for anteroposterior blastema polarity in planarian regeneration
    Christian P Petersen
    Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA
    Science 319:327-30. 2008
    ..Posterior-facing blastemas regenerate a head instead of a tail in Smed-betacatenin-1(RNAi) animals...
  10. ncbi Genetic and environmental influences on birth weight, birth length, head circumference, and gestational age by use of population-based parent-offspring data
    Astrid Lunde
    Section for Epidemiology and Medical Statistics, Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
    Am J Epidemiol 165:734-41. 2007
    ..and shared sibling environmental effects on birth weight and gestational age and also on crown-heel length and head circumference...
  11. ncbi Evidence of brain overgrowth in the first year of life in autism
    Eric Courchesne
    Department of Neuroscience, School of Medicine, University of California, San Diego, La Jolla, USA
    JAMA 290:337-44. 2003
    ..This raises the possibility that brain overgrowth begins much earlier, perhaps before the first clinically noticeable behavioral symptoms...
  12. doi Reactivating head regrowth in a regeneration-deficient planarian species
    S Y Liu
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany
    Nature 500:81-4. 2013
    ..Tissue fragments cut from the posterior half of the body of this species are unable to regenerate a head and ultimately die...
  13. ncbi twist is required in head mesenchyme for cranial neural tube morphogenesis
    Z F Chen
    Department of Molecular Genetics, University of Texas, M D Anderson Cancer Center, Houston 77030, USA
    Genes Dev 9:686-99. 1995
    ..Mutant embryos also had defects in head mesenchyme, somites, and limb buds...
  14. pmc A new magnetic resonance electrical impedance tomography (MREIT) algorithm: the RSM-MREIT algorithm with applications to estimation of human head conductivity
    Nuo Gao
    College of Electrical Engineering, Zhejiang University, People s Republic of China
    Phys Med Biol 51:3067-83. 2006
    ..electrical conductivity values of the scalp, the skull and the brain tissue, in a three-shell piecewise homogeneous head model...
  15. pmc Birth weight, head circumference, and prenatal exposure to acrylamide from maternal diet: the European prospective mother-child study (NewGeneris)
    Marie Pedersen
    Centre for Research in Environmental Epidemiology CREAL, Barcelona, Spain
    Environ Health Perspect 120:1739-45. 2012
    ..Acrylamide is a common dietary exposure that crosses the human placenta. It is classified as a probable human carcinogen, and developmental toxicity has been observed in rodents...
  16. doi Modeling the electric field induced in a high resolution realistic head model during transcranial current stimulation
    R Salvador
    Institute of Biophysics and Biomedical Engineering IBEB, Faculty of Sciences, Lisbon 1749 016, Portugal
    Conf Proc IEEE Eng Med Biol Soc 2010:2073-6. 2010
    ..distribution in transcranial current stimulation (tCS) still relies on results obtained from layered spherical head models...
  17. pmc The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals
    S Piccolo
    Howard Hughes Medical Institute and Department of Biological Chemistry, University of California, Los Angeles 90095 1662, USA
    Nature 397:707-10. 1999
    Embryological and genetic evidence indicates that the vertebrate head is induced by a different set of signals from those that organize trunk-tail development...
  18. pmc Repressor activity of Headless/Tcf3 is essential for vertebrate head formation
    C H Kim
    Laboratory of Molecular Genetics, NICHD, NHGRI, NIH, Bethesda, Maryland 20892, USA
    Nature 407:913-6. 2000
    ..can induce a complete body axis when transplanted to the ventral side of a host embryo by virtue of its distinct head and trunk inducing properties...
  19. ncbi 10/20, 10/10, and 10/5 systems revisited: their validity as relative head-surface-based positioning systems
    Valer Jurcak
    Sensory and Cognitive Food Science Laboratory, National Food Research Institute, 2 1 12 Kannondai, Tsukuba 305 8642, Japan
    Neuroimage 34:1600-11. 2007
    ..However, their effectiveness as relative head-surface-based positioning systems has not been examined...
  20. pmc Common variants at 12q15 and 12q24 are associated with infant head circumference
    H Rob Taal
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Nat Genet 44:532-8. 2012
    To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth ..
  21. pmc Diffuse optical imaging of the whole head
    Maria Angela Franceschini
    Massachusetts General Hospital, Athinoula A Martinos Center for Biomedical Imaging, 13th Street, Bldg 149 RM 2301, Charlestown, Massachusetts 02129, USA
    J Biomed Opt 11:054007. 2006
    ..DOI system has 32 detectors and 32 sources; by arranging them in a specific pattern, we can cover most of the adult head. With the increased number of optodes, we can collect optical data from prefrontal, sensorimotor, and visual ..
  22. doi Transcranial direct current stimulation (tDCS) in a realistic head model
    ROSALIND J SADLEIR
    J Crayton Pruitt Department of Biomedical Engineering, University of Florida, Box 116131, Gainesville, FL 32611 6131, USA
    Neuroimage 51:1310-8. 2010
    ..A model of the entire human head and brain was made using a finely meshed (1.1x1.1x1...
  23. ncbi Acceleration patterns of the head and pelvis when walking are associated with risk of falling in community-dwelling older people
    Hylton B Menz
    Prince of Wales Medical Research Institute, University of New South Wales, High Street, Randwick, NSW 2031, Australia
    J Gerontol A Biol Sci Med Sci 58:M446-52. 2003
    ..This study evaluated acceleration patterns of the head and pelvis when walking on a level and an unpredictably irregular surface to determine whether older people at risk ..
  24. ncbi Walking speed, cadence and step length are selected to optimize the stability of head and pelvis accelerations
    Mark D Latt
    Department of Geriatric Medicine, Westmead Hospital, Westmead, NSW, Australia
    Exp Brain Res 184:201-9. 2008
    ..hypothesis that an individual's preferred or usual walking speed, step length and cadence optimize the stability of head and pelvic accelerations in vertical (V), anterior-posterior (AP) and medio-lateral (ML) planes when walking...
  25. ncbi Coupling of fingertip somatosensory information to head and body sway
    J J Jeka
    Department of Kinesiology, University of Maryland, College Park 20742 2611, USA
    Exp Brain Res 113:475-83. 1997
    ..Postural sway was highly coherent with contact surface motion. Head and body sway assumed the frequency of the moving contact surface at all test frequencies...
  26. doi Silencing of Smed-betacatenin1 generates radial-like hypercephalized planarians
    Marta Iglesias
    Departament de Genetica, Universitat de Barcelona, 08028 Barcelona, Spain
    Development 135:1215-21. 2008
    ..mediterranea beta-catenins could be functionally specialized and that only Smed-betacatenin1 is involved in Wnt signalling...
  27. doi Essential head tremor is associated with cerebellar vermis atrophy: a volumetric and voxel-based morphometry MR imaging study
    A Quattrone
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    AJNR Am J Neuroradiol 29:1692-7. 2008
    ..Our aim was to investigate the presence of brain gray matter (GM) abnormalities in patients with different forms of essential tremor (ET)...
  28. doi A role for the head-direction system in geometric learning
    Seralynne D Vann
    School of Psychology, Cardiff University, 70 Park Place, Cardiff, CF10 3AT, UK
    Behav Brain Res 224:201-6. 2011
    Several recent models of episodic memory have highlighted a potential contribution from the head-direction system; there is, however, surprisingly little known about the behavioural effects of selective lesions within the head-direction ..
  29. pmc Travelling and splitting of a wave of hedgehog expression involved in spider-head segmentation
    Masaki Kanayama
    JT Biohistory Research Hall, Murasaki cho, Takatsuki, Osaka, Japan
    Nat Commun 2:500. 2011
    ..Here we show temporally repeated splitting of gene expression into stripes that is associated with head axis growth in the spider Achaearanea embryo...
  30. pmc The fine structure of honeybee head and body yaw movements in a homing task
    Norbert Boeddeker
    Bielefeld University, Neurobiology and Center of Excellence Cognitive Interaction Technology, Bielefeld, Germany
    Proc Biol Sci 277:1899-906. 2010
    Honeybees turn their thorax and thus their flight motor to change direction or to fly sideways. If the bee's head were fixed to its thorax, such movements would have great impact on vision...
  31. doi Selective head cooling with mild systemic hypothermia after neonatal hypoxic-ischemic encephalopathy: a multicenter randomized controlled trial in China
    Wen Hao Zhou
    Children s Hospital of Fudan University, Shanghai, China
    J Pediatr 157:367-72, 372.e1-3. 2010
    To investigate the efficacy and safety of selective head cooling with mild systemic hypothermia in hypoxic-ischemic encephalopathy (HIE) in newborn infants.
  32. doi Maternal seafood consumption and infant birth weight, length and head circumference in the Norwegian Mother and Child Cohort Study
    Anne Lise Brantsæter
    Division of Environmental Medicine, Norwegian Institute of Public Health, Nydalen, Oslo, Norway
    Br J Nutr 107:436-44. 2012
    ..seafood, subtypes of seafood and supplementary n-3 fatty acids were associated with infant birth weight, length and head circumference in a prospective study in Norway...
  33. pmc Anterior visceral endoderm directs ventral morphogenesis and placement of head and heart via BMP2 expression
    Mary Madabhushi
    Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA
    Dev Cell 21:907-19. 2011
    ..results in human birth defects involving body wall, gut, and heart malformations and in mouse misplacement of head and heart...
  34. doi Head lag in infants at risk for autism: a preliminary study
    Joanne E Flanagan
    Kennedy Krieger Institute, Baltimore, MD 21211, USA
    Am J Occup Ther 66:577-85. 2012
    ..We examined the association between head lag during pull-to-sit at age 6 mo and autism risk status. METHOD...
  35. ncbi A human parietal face area contains aligned head-centered visual and tactile maps
    Martin I Sereno
    Department of Cognitive Science, Institute for Neural Computation, University of California San Diego, La Jolla, California 92093, USA
    Nat Neurosci 9:1337-43. 2006
    ..We show that this area may code the location of visual stimuli with respect to the face, not with respect to the retina...
  36. ncbi The evolution of arthropod heads: reconciling morphological, developmental and palaeontological evidence
    Gerhard Scholtz
    Humboldt Universitat zu Berlin, Institut für Biologie Vergleichende Zoologie, Philippstrasse 13, 10115 Berlin, Germany
    Dev Genes Evol 216:395-415. 2006
    Understanding the head is one of the great challenges in the fields of comparative anatomy, developmental biology, and palaeontology of arthropods...
  37. pmc Genomic and functional studies of Drosophila sex hierarchy regulated gene expression in adult head and nervous system tissues
    Thomas D Goldman
    Section of Molecular and Computational Biology, Department of Biological Sciences, University of Southern California Los Angeles, Los Angeles, California, United States of America
    PLoS Genet 3:e216. 2007
    ..specification of reproductive behaviors and physiology, we identified genes expressed in the adult head and central nervous system that are regulated downstream of sex-specific transcription factors encoded by doublesex ..
  38. ncbi Mouse Otx2 functions in the formation and patterning of rostral head
    I Matsuo
    Department of Morphogenesis, Kumamoto University School of Medicine, Japan
    Genes Dev 9:2646-58. 1995
    The anterior part of the vertebrate head expresses a group of homeo box genes in segmentally restricted patterns during embryogenesis. Among these, Otx2 expression covers the entire fore- and midbrains and takes place earliest...
  39. ncbi Monte Carlo prediction of near-infrared light propagation in realistic adult and neonatal head models
    Yuich Fukui
    Department of Electronics and Electrical Engineering, Keio University, 3 141, Hyoshi, Kohoku Ku, Yokohama 223 8522, Japan
    Appl Opt 42:2881-7. 2003
    ..The effect of the heterogeneous structure of the head on light propagation in the adult brain is likely to be different from that in the neonatal brain because the ..
  40. ncbi A balance of FGF, BMP and WNT signalling positions the future placode territory in the head
    Anna Litsiou
    Department of Craniofacial Development, Guys Campus, Guys Tower, Floor 27, King s College London, London SE1 9RT, UK
    Development 132:4051-62. 2005
    The sensory nervous system in the vertebrate head arises from two different cell populations: neural crest and placodal cells. By contrast, in the trunk it originates from neural crest only...
  41. pmc The TALE class homeobox gene Smed-prep defines the anterior compartment for head regeneration
    Daniel A Felix
    Institute of Genetics, Queen s Medical Centre, University of Nottingham, United Kingdom
    PLoS Genet 6:e1000915. 2010
    ..Together our results suggest that Smed-prep is required in stem cell progeny as they form the anterior regenerative blastema and is required for specifying anterior cell fates and correct patterning...
  42. doi Revised birth centiles for weight, length and head circumference in the UK-WHO growth charts
    Tim J Cole
    Medical Statistics, UCL Institute of Child Health, University College London, London, UK
    Ann Hum Biol 38:7-11. 2011
    ..The pre-existing British 1990 reference birth centiles, used in the UK since 1995, had been biased by the inclusion of post-natal data...
  43. pmc Quantitative relationship between axonal injury and mechanical response in a rodent head impact acceleration model
    Yan Li
    Department of Biomedical Engineering, Wayne State University, Detroit, Michigan 48201, USA
    J Neurotrauma 28:1767-82. 2011
    ..25 m or 2.25 m. An accelerometer and angular rate sensor measured the linear and angular responses of the head, while the impact event was captured by a high-speed video camera...
  44. ncbi Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer
    T Bouwmeester
    Howard Hughes Medical Institute and Department of Biological Chemistry, University of California, Los Angeles, 90095 1737, USA
    Nature 382:595-601. 1996
    ..The results suggest a role for a molecule expressed in the anterior endoderm in the induction of head structures in the vertebrate embryo.
  45. ncbi Rapidly evolving genes of Drosophila: differing levels of selective pressure in testis, ovary, and head tissues between sibling species
    Santosh Jagadeeshan
    Department of Biology, McMaster University, Hamilton, Ontario, Canada
    Mol Biol Evol 22:1793-801. 2005
    ..We screened testis, ovary, and head tissues to identify and characterize rapidly evolving genes (REGs) between closely related species...
  46. pmc Caloric and search-coil head-impulse testing in patients after vestibular neuritis
    A Schmid-Priscoveanu
    Department of Neurology, Zurich University Hospital, Switzerland
    J Assoc Res Otolaryngol 2:72-8. 2001
    The objective of this study was to compare results of quantitative head-impulse testing using search coils with eye-movement responses to caloric irrigation in patients with unilateral vestibular hypofunction after vestibular neuritis...
  47. ncbi Is there a relationship between head posture and craniomandibular pain?
    C M Visscher
    Department of Oral Function, Academic Centre for Dentistry Amsterdam, Amsterdam, The Netherlands
    J Oral Rehabil 29:1030-6. 2002
    An often-suggested factor in the aetiology of craniomandibular disorders (CMD) is an anteroposition of the head. However, the results of clinical studies to the relationship between CMD and head posture are contradictory...
  48. ncbi Allometric scaling and proportion regulation in the freshwater planarian Schmidtea mediterranea
    Néstor J Oviedo
    University of Utah School of Medicine, Department of Neurobiology and Anatomy, Salt Lake City, Utah 84132, USA
    Dev Dyn 226:326-33. 2003
    ..We have named H.112.3c cintillo ("head ribbon" in Spanish) and present a strategy for using the expression of this gene to monitor scale and ..
  49. ncbi Trigeminal somatosensory innervation of the head of a teleost fish with particular reference to nociception
    Lynne U Sneddon
    Roslin Institute, Welfare Biology, Roslin, Midlothian EH25 9PS, UK
    Brain Res 972:44-52. 2003
    ..the rainbow trout (Oncorhynchus mykiss) to determine what types of somatosensory receptors were present on the head of the trout specifically searching for nociceptors...
  50. ncbi Cranial neural crest and the building of the vertebrate head
    Fabio Santagati
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Centre National de la Recherche Scientifique, Université Lousis Pasteur, BP 10142 67404 Illkirch Cedex, CU de Strasbourg, France
    Nat Rev Neurosci 4:806-18. 2003
  51. ncbi The active head-impulse test in unilateral peripheral vestibulopathy
    Ross A Black
    Department of Neurology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Sydney, Australia
    Arch Neurol 62:290-3. 2005
    The head-impulse test, which is sensitive and specific for detecting severe unilateral peripheral vestibulopathy, is an accepted part of the neurological examination, especially in patients with vertigo and balance disorders.
  52. ncbi Nociception in fish: stimulus-response properties of receptors on the head of trout Oncorhynchus mykiss
    Paul J Ashley
    University of Liverpool, School of Biological Sciences, The BioScience Building, Liverpool, L69 7ZB, UK
    Brain Res 1166:47-54. 2007
    This study examined stimulus-response properties of somatosensory receptors on the head of rainbow trout, Oncorhynchus mykiss, using extracellular recording from single cells in the trigeminal ganglion...
  53. doi Effect of head size on diffusion tensor imaging
    Hidemasa Takao
    Department of Radiology, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
    Neuroimage 57:958-67. 2011
    b>Head size markedly differs among individuals. To our knowledge, there have been no studies that systematically investigated the effect of head size on diffusion tensor measures of the brain...
  54. doi Evaluation of multiple-sphere head models for MEG source localization
    M Lalancette
    Department of Diagnostic Imaging, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario M5G1X8, Canada
    Phys Med Biol 56:5621-35. 2011
    Magnetoencephalography (MEG) source analysis has largely relied on spherical conductor models of the head to simplify forward calculations of the brain's magnetic field...
  55. pmc Initiating head development in mouse embryos: integrating signalling and transcriptional activity
    Ruth M Arkell
    Early Mammalian Development Laboratory, Research School of Biology, College of Medicine, Biology and Environment, Australian National University, Canberra, Australian Capital Territory, Australia
    Open Biol 2:120030. 2012
    ..The initial formation of the anterior (head) structures in the mouse embryo is critically dependent on the morphogenetic activity emanating from two signalling ..
  56. pmc Depth-compensated diffuse optical tomography enhanced by general linear model analysis and an anatomical atlas of human head
    Fenghua Tian
    Department of Bioengineering, Joint Program in Biomedical Engineering between UT Arlington and UT Southwestern Medical Center at Dallas, University of Texas at Arlington, Arlington, TX, USA
    Neuroimage 85:166-80. 2014
    ..However, the semi-infinite model that was used in DCA deviated significantly from the realistic human head anatomy...
  57. ncbi Growth control in the proliferative region of the Drosophila eye-head primordium: the elbow-noc gene complex
    Carlos M Luque
    ICREA and Institute for Research in Biomedicine IRB, Parc Cientific de Barcelona, Josep Samitier, 1 5, 08028 Barcelona, Spain
    Dev Biol 301:327-39. 2007
    ..Notch activation at the dorsal-ventral boundary of the Drosophila eye-head primordium leads to the expression of the secreted protein Unpaired, a ligand of the JAK-STAT pathway that induces ..
  58. doi Differential gene expression in the honeybee head after a bacterial challenge
    Bieke Scharlaken
    Laboratory of Zoophysiology, Department of Biochemistry, Physiology and Microbiology, Faculty of Science, Ghent University, Ghent, Belgium
    Dev Comp Immunol 32:883-9. 2008
    ..Using quantitative real-time PCR, we present evidence that gene expression in the honeybee head is influenced by activation of the immune system 8h after a bacterial challenge with Escherichia coli...
  59. pmc Hyperthermia impairs short-term memory and peripheral motor drive transmission
    S Racinais
    ASPETAR, Qatar Orthopaedic and Sports Medicine Hospital, Exercise and Sports Science Department, Doha, Qatar
    J Physiol 586:4751-62. 2008
    ..were to determine (i) the effect of passive hyperthermia on motor drive and cognitive function, and (ii) whether head cooling can limit the hyperthermia-induced alterations...
  60. doi Clinical characteristics of people with head nodding in southern Tanzania
    Andrea S Winkler
    Interdisciplinary Centre for Palliative Medicine and Department of Neurology, Ludwig Maximilians University, Munich, Germany
    Trop Doct 40:173-5. 2010
    We have previously described a seizure disorder characterized by head nodding (HN). In a prospective study in southern Tanzania, we evaluated 62 patients with HN...
  61. pmc Sound pressure transformations by the head and pinnae of the adult Chinchilla (Chinchilla lanigera)
    Kanthaiah Koka
    Department of Physiology and Biophysics, University of Colorado Medical School, Aurora, CO, USA
    Hear Res 272:135-47. 2011
    ..These cues are generated by the spatial- and frequency-dependent filtering of propagating sound waves by the head and external ears...
  62. pmc Combining classical and molecular approaches elaborates on the complexity of mechanisms underpinning anterior regeneration
    Deborah J Evans
    Centre for Genetics and Genomics, Queen s Medical Centre, University of Nottingham, Nottingham, United Kingdom
    PLoS ONE 6:e27927. 2011
    ..Together these insights start to delineate the interplay between discrete existing, new, and then later homeostatic signals in AP axis regeneration...
  63. doi Mechanics of blast loading on the head models in the study of traumatic brain injury using experimental and computational approaches
    S Ganpule
    Department of Mechanical and Materials Engineering, University of Nebraska Lincoln, Lincoln, NE 68588 0656, USA
    Biomech Model Mechanobiol 12:511-31. 2013
    ..To understand the interactions of blast waves on the head and brain and to identify the mechanisms of injury, compression-driven air shock tubes are extensively used in ..
  64. pmc Characterization of head transcriptome and analysis of gene expression involved in caste differentiation and aggression in Odontotermes formosanus (Shiraki)
    Qiuying Huang
    Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, Huazhong Agricultural University, Wuhan, China
    PLoS ONE 7:e50383. 2012
    ..formosanus. Hence, studies on transcriptome and gene expression profiling are helpful to better understand molecular basis underlying caste differentiation and aggressive behavior in O. formosanus...
  65. ncbi Head regeneration in Hydra
    Hans R Bode
    Developmental Biology Center and Department of Developmental and Cell Biology, University of California, Irvine, California 92697, USA
    Dev Dyn 226:225-36. 2003
    Hydra, a primitive metazoan, has a simple structure consisting of a head, body column, and foot aligned along a single oral-aboral axis. The body column has a high capacity for regeneration of both the head and foot...
  66. ncbi Hensen's node gives rise to the ventral midline of the foregut: implications for organizing head and heart development
    Margaret L Kirby
    Neonatal Perinatal Research Institute, Division of Neonatology, Department of Pediatrics, Box 3179, Duke University Medical Center, Durham, NC 27710, USA
    Dev Biol 253:175-88. 2003
    Patterning of the ventral head has been attributed to various cell populations, including endoderm, mesoderm, and neural crest...
  67. ncbi Reevaluation of near-infrared light propagation in the adult human head: implications for functional near-infrared spectroscopy
    Yoko Hoshi
    Tokyo Institute of Psychiatry, Department of Integrated Neuroscience, 2 1 8 Kamikitazawa, Setagaya Ku, Tokyo 156 8585, Japan
    J Biomed Opt 10:064032. 2005
    Using both experimental and theoretical methods, we examine the contribution of different parts of the head to near-IR (NIR) signal...
  68. ncbi Microbiology and antibiotic sensitivities of head and neck space infections of odontogenic origin
    Anthony J Rega
    Department of Oral and Maxillofacial Surgery, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103 2400, USA
    J Oral Maxillofac Surg 64:1377-80. 2006
    The purpose of this study is to assess the anatomical spaces and causative micro-organisms responsible for deep fascial space head and neck infections and evaluate the resistance of antibiotics used in the treatment of these infections.
  69. doi Conebeam CT of the head and neck, part 2: clinical applications
    A C Miracle
    Departments of Radiology, University of Michigan Health System, University Hospital, Ann Arbor, Mich 48109 5030, USA
    AJNR Am J Neuroradiol 30:1285-92. 2009
    Conebeam x-ray CT (CBCT) is being increasingly used for point-of-service head and neck and dentomaxillofacial imaging...
  70. doi Anticipating intentional actions: the effect of eye gaze direction on the judgment of head rotation
    Matthew Hudson
    School of Psychology, Bangor University, Adeilad Brigantia, Penrallt Road, Bangor, United Kingdom
    Cognition 112:423-34. 2009
    ..momentum paradigm, this study investigated the hypothesis that judgments of how far another agent's head has rotated are influenced by the perceived gaze direction of the head...
  71. pmc Yellow-e determines the color pattern of larval head and tail spots of the silkworm Bombyx mori
    Katsuhiko Ito
    Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Yayoi 1 1 1, Bunkyo ku, Tokyo 113 8657, Japan
    J Biol Chem 285:5624-9. 2010
    ..In two mutant strains, bts and its allele bts2, of the silkworm Bombyx mori, the larval head cuticle and anal plates are reddish brown instead of the white color found in the wild type...
  72. doi Head patterning and Hox gene expression in an onychophoran and its implications for the arthropod head problem
    Bo Joakim Eriksson
    University Museum of Zoology and Department of Zoology, Downing Street, Cambridge, CB2 3EJ, UK
    Dev Genes Evol 220:117-22. 2010
    The arthropod head problem has puzzled zoologists for more than a century. The head of adult arthropods is a complex structure resulting from the modification, fusion and migration of an uncertain number of segments...
  73. ncbi Pectoralis major myocutaneous flaps for head and neck reconstruction: factors influencing occurrences of complications and the final outcome
    Fábio Roberto Pinto
    FMABC, Sao Bernardo do Campo, Sao Paulo, Brazil
    Sao Paulo Med J 128:336-41. 2010
    ..The aim of this study was to identify factors that may cause complications and influence the final result from reconstructions using pectoralis major myocutaneous flaps (PMMFs) for head and neck defect repair following cancer resection.
  74. pmc Pharyngeal mesoderm development during embryogenesis: implications for both heart and head myogenesis
    Eldad Tzahor
    Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel
    Cardiovasc Res 91:196-202. 2011
    The pharyngeal mesoderm (PM), located in the head region of the developing embryo, recently triggered renewed interest as the major source of cells contributing to broad regions of the heart as well as to the head musculature...
  75. pmc Simulation of near-infrared light absorption considering individual head and prefrontal cortex anatomy: implications for optical neuroimaging
    Florian B Haeussinger
    Department of Psychiatry and Psychotherapy, University of Tuebingen, Tuebingen, Germany
    PLoS ONE 6:e26377. 2011
    ..57) and was reduced by 41.5% in subjects with relatively large compared to small frontal sinus. Head circumference was significantly positively correlated with the mean SCD (r=...
  76. ncbi Head direction, place, and movement correlates for cells in the rat retrosplenial cortex
    J Cho
    Department of Neurobiology, University of California, Los Angeles, USA
    Behav Neurosci 115:3-25. 2001
    ..L. Chen, L. H. Lin, E. J. Green, C. A. Barnes, & B. L. McNaughton, 1994), the authors found head direction cells with properties similar to those in other areas. These cells were slightly anticipatory...
  77. ncbi Randomized study comparing the "sniffing position" with simple head extension for laryngoscopic view in elective surgery patients
    F Adnet
    Department of Anesthesiology, Hĵpital Avicenne, University Paris 13, France
    Anesthesiology 95:836-41. 2001
    ..However, no study to date has confirmed its superiority over simple head extension...
  78. ncbi C. elegans responds to chemical repellents by integrating sensory inputs from the head and the tail
    Massimo A Hilliard
    International Institute of Genetics and Biophysics, CNR, 80131 Naples, Italy
    Curr Biol 12:730-4. 2002
    ..The similar structures of the phasmids and the amphid chemosensory organs in the head have long suggested a chemosensory function for the phasmids...
  79. ncbi Relationship between head circumference and brain volume in healthy normal toddlers, children, and adults
    H H Bartholomeusz
    Center for Autism Research, Children s Hospital of San Diego, La Jolla, CA 92037, USA
    Neuropediatrics 33:239-41. 2002
    To quantify the relationship between brain volume and head circumference from early childhood to adulthood, and quantify how this relationship changes with age.
  80. ncbi Generic head models for atlas-based EEG source analysis
    Felix Darvas
    Signal and Image Processing Institute, University of Southern California, Los Angeles, California 90089 2564, USA
    Hum Brain Mapp 27:129-43. 2006
    We describe a method for using a generic head model, in the form of an anatomical atlas, to produce EEG source localizations. The atlas is fitted to the subject by a nonrigid warp using a set of surface landmarks...
  81. doi Variability of blowfly head optomotor responses
    R Rosner
    Lehrstuhl für Neurobiologie, Universitat Bielefeld, Bielefeld, Germany
    J Exp Biol 212:1170-84. 2009
    ..In the present study, we analyse the variability of visually induced head pitch responses of tethered blowflies by high-speed cinematography...
  82. pmc Polarized notum activation at wounds inhibits Wnt function to promote planarian head regeneration
    Christian P Petersen
    Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
    Science 332:852-5. 2011
    Regeneration requires initiation of programs tailored to the identity of missing parts. Head-versus-tail regeneration in planarians presents a paradigm for study of this phenomenon. After injury, Wnt signaling promotes tail regeneration...
  83. pmc Theta-modulated head direction cells in the rat anterior thalamus
    Marian Tsanov
    Trinity College Institute of Neuroscience, School of Psychology, Trinity College Dublin, Dublin 2, Ireland
    J Neurosci 31:9489-502. 2011
    ..Theta rhythm and head directionality are the two main signals found across all levels of Papez's circuit, which supports episodic memory ..
  84. doi Mouse embryonic head as a site for hematopoietic stem cell development
    Zhuan Li
    307 Ivy Translational Medicine Center, Laboratory of Oncology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing 100071, China
    Cell Stem Cell 11:663-75. 2012
    ..Here we report that, in parallel to the AGM region, the E10.5-E11.5 mouse head harbors bona fide HSCs, as defined by long-term, high-level, multilineage reconstitution and self-renewal capacity ..
  85. pmc Genomic diversity and evolution of the head crest in the rock pigeon
    Michael D Shapiro
    Department of Biology, University of Utah, Salt Lake City, UT 84112, USA
    Science 339:1063-7. 2013
    ..We identified the gene EphB2 as a strong candidate for the derived head crest phenotype shared by numerous breeds, an important trait in mate selection in many avian species...
  86. ncbi Eye-head coordination for the steering of locomotion in humans: an anticipatory synergy
    R Grasso
    Section of Human Physiology, Scientific Institute S Lucia, Rome, Italy
    Neurosci Lett 253:115-8. 1998
    We investigated head and gaze orientation in six healthy volunteers walking along 90 degrees corner trajectories, both at light and with eyes closed...
  87. ncbi Goosecoid promotes head organizer activity by direct repression of Xwnt8 in Spemann's organizer
    J Yao
    Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6058, USA
    Development 128:2975-87. 2001
    Formation of the vertebrate body plan is controlled by discrete head and trunk organizers that establish the anteroposterior pattern of the body axis...
  88. pmc Optimal fetal growth for the Caucasian singleton and assessment of appropriateness of fetal growth: an analysis of a total population perinatal database
    Eve M Blair
    Centre for Child Health Research, The University of Western Australia, at the Telethon Institute for Child Health Research, P, O, Box 855, West Perth, WA, 6872, Australia
    BMC Pediatr 5:13. 2005
    ..Appropriateness of growth can then be inferred from the ratio of the value of the observed dimension to that of the optimal dimension...
  89. pmc Distinct origins and genetic programs of head muscle satellite cells
    Itamar Harel
    Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel
    Dev Cell 16:822-32. 2009
    ..Similar lineage heterogeneity is seen within the head musculature and satellite cells, due to their shared, heterogenic embryonic origins...
  90. pmc Neuroelectromagnetic forward head modeling toolbox
    Zeynep Akalin Acar
    Swartz Center for Computational Neuroscience, Institute for Neural Computation, University of California San Diego, La Jolla, CA 92093 0961, USA
    J Neurosci Methods 190:258-70. 2010
    This paper introduces a Neuroelectromagnetic Forward Head Modeling Toolbox (NFT) running under MATLAB (The Mathworks, Inc...
  91. ncbi Novel segment polarity gene interactions during embryonic head development in Drosophila
    A Gallitano-Mendel
    Department of Neuroscience, University of Pennsylvania, Philadelphia 19104 6074, USA
    Dev Biol 192:599-613. 1997
    ..regulation of the genes hedgehog (hh), wingless (wg), and engrailed (en) in each of the segments of the developing head. We show that the cross-regulatory relationships among these genes, as well as their initial mode of activation, in ..
  92. ncbi Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development
    M Grigoriou
    Division of Developmental Neurobiology, The National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
    Development 125:2063-74. 1998
    ..We suggest that Fgf8 and Lhx6 and Lhx7 are key components of signalling cascades which determine morphogenesis and differentiation in the first branchial arch and the basal forebrain...
  93. ncbi A population-based atlas and clinical target volume for the head-and-neck lymph nodes
    Ian Poon
    Department of Radiation Medicine, Toronto Sunnybrook Cancer Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Int J Radiat Oncol Biol Phys 59:1301-11. 2004
    To develop a population-based three-dimensional lymph node target volume of the head and neck.
  94. ncbi Surgery and adjuvant radiotherapy in patients with cutaneous head and neck squamous cell carcinoma metastatic to lymph nodes: combined treatment should be considered best practice
    Michael J Veness
    Head and Neck Cancer Service, Westmead Hospital, University of Sydney, Sydney, Australia michael radonc wsahs nsw gov au
    Laryngoscope 115:870-5. 2005
    Patients with cutaneous squamous cell carcinoma (SCC) may develop metastatic SCC to nodes in the head and neck. Recent data support best outcome with the addition of adjuvant radiotherapy...
  95. ncbi Cue control and head direction cells
    J P Goodridge
    Department of Psychology, Dartmouth College, Hanover, New Hampshire 03755, USA
    Behav Neurosci 112:749-61. 1998
    Previous research has shown that head direction (HD) cells in both the anterior dorsal thalamus (ADN) and the postsubiculum (PoS) in rats discharge in relation to familiar, visual landmarks in the environment...
  96. ncbi Effect of maternal bone lead on length and head circumference of newborns and 1-month-old infants
    Mauricio Hernandez-Avila
    Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica, Morelos, Mexico
    Arch Environ Health 57:482-8. 2002
    ..Patella lead was positively and significantly related to the risk of a low head circumference score; this score remained unaffected by inclusion of birth weight...
  97. ncbi Melanoma of the head and neck: current concepts in staging, diagnosis, and management
    Maher N Younes
    Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Box 441, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Surg Oncol Clin N Am 13:201-29. 2004
    ..Finally, new advances in diagnostic and treatment strategies carry the hope for further improvements in locoregional control and survival rates...
  98. ncbi Parietal area VIP neuronal responses to heading stimuli are encoded in head-centered coordinates
    Tao Zhang
    Center for Neuroscience, University of California, Davis, Davis, CA 95616, USA
    Neuron 42:993-1001. 2004
    ..This stability was such that the population of VIP neurons represented heading very nearly in head-centered coordinates...
  99. ncbi Organ specification-growth control connection: new in-sights from the Drosophila eye-antennal disc
    Maria Dominguez
    Instituto de Neurociencias, CSIC UMH, Campus de Sant Joan, Alicante, Spain
    Dev Dyn 232:673-84. 2005
    ..The eye-antennal disc gives origin not only to the compound eye but also to the head capsule, ocelli, maxillary palp, and antenna, and these organs develop bearing constant size proportions with each ..
  100. ncbi Muscle development: forming the head and trunk muscles
    Hung Ping Shih
    Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, OR 97331, USA
    Acta Histochem 110:97-108. 2008
    ..Different states of the network specify pre-myogenic progenitor cells in the head and trunk...
  101. pmc CD44s and CD44v6 expression in head and neck epithelia
    Brigitte Mack
    Department of Otorhinolaryngology, Head and Neck Surgery, Grosshadern Medical Center, Ludwig Maximilians University of Munich, Munich, Germany
    PLoS ONE 3:e3360. 2008
    ..form of CD44 (CD44s) was shown to be part of the signature of cancer stem cells (CSCs) in colon, breast, and in head and neck squamous cell carcinomas (HNSCC)...

Research Grants83

  1. STATISITICAL DESIGN, MONITORING &COORD. OF VISION CLINICAL TRIALS &EPIDEMIOLOGY
    Keri Hammel; Fiscal Year: 2012
    ..The hair will be collected from the back of the head, and the skin will be collected from the inside of the upper arm...
  2. STATISITICAL DESIGN, MONITORING &COORD. OF VISION CLINICAL TRIALS &EPIDEMIOLOGY
    Keri Hammel; Fiscal Year: 2013
    ..The hair will be collected from the back of the head, and the skin will be collected from the inside of the upper arm...
  3. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
    ..abstract_text> ..
  4. NIH Director's Pioneer Award
    ERICH JARVIS; Fiscal Year: 2009
    ..Repairing the pathway in vocal learners, when damaged, would have profound impact for correcting neurological disorders of speech. ..
  5. Anti-tumor properties of curcumin in oral cancers: role of thioredoxin reductase
    STEPHEN WILLIAM TUTTLE; Fiscal Year: 2010
    ..can be readily translated into a chemoprevention schemes or combined chemo-radiation therapy protocol for treating head and neck cancers...
  6. Optimized Growth Media to Detect Intracellular Bacteria Implicated in Chronic Dis
    PATRICIA MASCARELLI; Fiscal Year: 2011
    ..Phase Ii research would also address the potential changes in the BAPGM Axenic Culture Bottle head-space gas composition required to maximize bacteria recovery and growth and that might lead to an optimization of ..
  7. Charles W Wilkinson; Fiscal Year: 2016
    ..gold standard test for both GHD and sAI, requires intensive medical supervision and is contraindicated in cases of head injury, so it cannot be employed to diagnose GHD or sAI in OIF/OEF Veterans with mTBI...
  8. Polycyclic aromatic hydrocarbons and birth outcomes in Mexico City
    MARIE SYLVIA O'NEILL; Fiscal Year: 2013
    ..We will evaluate whether ambient pollution and PAH adducts are associated with three outcomes: birth weight, head circumference and birth length, controlling for other risk factors, and which time windows are most relevant...
  9. Translational Machinery in Stress Signaling and Tumor Suppression
    THOMAS J contact BEGLEY; Fiscal Year: 2010
    ..This hypothesis is based on our recent findings in colon and head and neck squamous carcinoma cell models that translational regulatory mechanisms inhibit tumor growth...
  10. Rac GTPase signaling during embryonic salivary gland branching morphogenesis
    Sharon Sequeira; Fiscal Year: 2012
    ..an autoimmune disease that targets saliva-secreting acinar tissue, 2) radiation and chemotherapeutic regimens for head and neck cancers and 3) adverse side effects from thousands of medications...
  11. Samuel D Crish; Fiscal Year: 2016
    ..e., to what degree it is due to functional loss of uptake/transport, blockade at the optic nerve head, axon loss, or RGC loss...
  12. 24th Annual Fanconi Anemia Research Fund Scientific Symposium
    GROVER CARLTON BAGBY; Fiscal Year: 2012
    ..of adult FA patients reveals a striking and ominous incidence of squamous cell carcinomas (SCC), especially of the head and neck and gynecological tract...
  13. Twenty-second Annual Fanconi Anemia Research Fund Scientific Symposium
    GROVER CARLTON BAGBY; Fiscal Year: 2010
    ..genes and FA gene expression have been reported in patients with sporadic malignancies of plasma cells, leukemia, head and neck cancer, lung cancer, and ovarian cancer...
  14. Emergency Neurophysiological Assessment Bedside Logic Engine
    Don M Tucker; Fiscal Year: 2010
    ..the knowledge assembled by an intelligent search tool (such as the clinical presentation of a patient with mild head trauma, together with expected complications such as hematoma) is used to provide a predictive analysis of the ..
  15. FOLLOW UP OF THE ALPHA-TOCOPHEROL, BETA-CAROTENE CANCER PREVENTION (ATBC) STUDY
    Jarmo Virtamo; Fiscal Year: 2010
    ..lung, 2,000 prostate, 700 colorectal, 500 bladder, 300-400 each for stomach, pancreas, and kidney cancers, 300 head and neck, and 1,100 for other sites combined...
  16. Computer/Electrical Engineering
    Theodore Raphan; Fiscal Year: 2011
    ..7. Utilize the Kunin/Raphan algorithms developed for humans and for head-fixed monkeys on a linear sled to determine the binocular fixation point of the eyes in space during monkey ..
  17. Molecular Epidemiology of DNA Repair in Head and Neck Cancer
    Qingyi Wei; Fiscal Year: 2012
    ..Tobacco and alcohol use and genetic susceptibility are major risk factors for squamous cell carcinoma of the head and neck (SCCHN)...
  18. MOLECULAR BIOLOGY OF HUMAN COAGULATION FACTOR V
    Thomas Ortel; Fiscal Year: 2010
    ..immersion of exposed hydrophobic residues in the apolar membrane core;(2) stereospecific interactions with PS head groups and (3) favorable electrostatic contacts of basic side chains with negatively charged membrane phosphate ..
  19. Dynamics of Kinesins, Dyneins, and Myosins
    Paul R Selvin; Fiscal Year: 2010
    ..At its most basic level, a single, isolated "head", which gives motors its ATP-dependent motility, has been fairly well studied...
  20. PARP inhibitor and Redox Catalyst Conjugate for Traumatic Brain Injury
    Kanneganti Murthy; Fiscal Year: 2012
    ..induction of cellular injury responses contributes importantly to the ultimate neurological outcome after severe head trauma...
  21. Enhancing radiation and cisplatin HNSCC cell killing by inhibiting mitochondrial
    Lynn Harrison; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Head and neck squamous cell carcinoma (HNSCC) is the ninth most common cancer worldwide. In the US there are 40-50,000 new cases a year and ~12,000 deaths due to HNSCC...
  22. Lois B Travis; Fiscal Year: 2016
    ..8 million patients are diagnosed with cancers of colon, rectum, cervix, endometrium, bladder, stomach, head and neck, lung, esophagus, pancreas, osteosarcoma, ovary, and testis, for which first-line therapy can potentially ..
  23. GARY ANDREW WEISMAN; Fiscal Year: 2016
    ..the autoimmune disease Sj[unreadable]gren's syndrome and as a result of [unreadable]-irradiation therapies for head and neck cancers...
  24. Sheng He Huang; Fiscal Year: 2014
    ..coli K1-induced NF-kB signaling. Vim forms a complex with IkB, NF-kB and tubulins in the resting cells through its head domain (HD). Vim- mediated modulation of the ubiquitin proteasome system (UPS) is essential for NF-kB activation...
  25. PKC delta and cell renewal in irradiated taste epithelium
    MARY ELAINE REYLAND; Fiscal Year: 2012
    ..Taste dysfunction, either loss or alteration in sensation, is a common occurrence during radiotherapy for head and neck cancer...
  26. A Rapid Point-of-care Diagnostic for Neisseria gonorrhoeae STDs
    Richard F Selden; Fiscal Year: 2012
    ..total of 12 GC loci (including MLST and antibiotic resistance loci) to be amplified simultaneously;and 3) Perform a head-to-head test of our diagnostic against two of the leading commercial GC diagnostics...
  27. Health Care Disparities in the Pacific Islands Pacific Regional Medical Conferenc
    SAIED SAFABAKHSH; Fiscal Year: 2011
    ..Certain cancers of head, neck, lung and breast are well-established to be more prevalent in this community compared to the U.S. mainland...
  28. Ephrin-A3 in Neuron-Glia Communication
    Elena B Pasquale; Fiscal Year: 2011
    ..Typically, mature spines have an enlarged head connected to the dendrite through a narrow neck...
  29. New Molecular and Cellular Mechanisms of Glaucoma
    Andrei Surguchov; Fiscal Year: 2013
    ..Abstract Glaucoma can be defined as progressive optic neuropathy with structural damage of the optic nerve (ON) head and selective death of retinal ganglion cells (RGC)...
  30. MOLECULAR BIOLOGY OF HEMORRHAGIC SHOCK
    Timothy R Billiar; Fiscal Year: 2013
    Trauma is the leading cause of death in this country in people under the age of 54 years. Except for major head injury, hemorrhage/tissue trauma and its consequences are the most important causes of morbidity and mortality in these often ..
  31. Susanna Scafidi; Fiscal Year: 2015
    ..leading cause of pediatric morbidity and mortality, yet, there is no specific treatment and a significant number of head-injured children suffer from life-long disabilities...
  32. Human developmental toxicity of metal mixture exposure from e-waste recycling
    Aimin Chen; Fiscal Year: 2010
    ..stillbirth, gestational length, preterm birth, birth weight, small for gestational age [SGA], birth length, head circumference, anogenital distance [AGD]), thyroid hormones (TSH, T4, T3), and infant neurodevelopment (Bayley ..
  33. A Cis-regulatory Model for Neural Border Induction
    Daniel Meulemans Medeiros; Fiscal Year: 2013
    ..this neural border domain to form diverse derivatives throughout the embryo, including bones and cartilage in the head, and portions of the cranial ganglia and heart...
  34. RRSS #08: Evaluating Prevalence HPV Infection Among Head and Neck Cancer Patients
    Dennis M Deapen; Fiscal Year: 2009
    b>Head and neck cancer (HNC) includes malignant tumors arising from a variety of sites in the upper aerodigestive tract (UADT), including the oral cavity, the pharynx, and the larynx...
  35. Human in Mouse Modeling of HNSCC to Predict Resonse to Therapy
    Wendell G Yarbrough; Fiscal Year: 2010
    ..b>Head and neck squamous cell carcinoma (HNSCC) is a devastating disease that is treated aggressively when diagnosed at ..
  36. A Rapid Point-of-care Diagnostic for C.trachomitis STDs
    RICHARD F contact SELDEN; Fiscal Year: 2010
    ..trachomatis strains and for epidemiologic studies);3) Secure patents for FDA approval;4) Design a head-to-head clinical study of our diagnostic against leading commercial diagnostics using clinical samples from diverse ..
  37. Biomarker Reference Laboratory, EDRN
    William E Grizzle; Fiscal Year: 2010
    ..The group includes pathologists and basic researchers with expertise in neoplastic processes of the skin, head and neck, lung, colorectum, pancreas, breast, ovary and cervix, as well as technical expertise in, and resources ..
  38. Sulie L Chang; Fiscal Year: 2014
    ..rats, and that these animals have greater METH-induced behavioral sensitization, as assessed by stereotypical head movement...
  39. Air Toxics, Neighborhood Environment and Risk of Oral Clefts
    Philip J Lupo; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Over 70% of all birth defects in humans affect the head and face...
  40. MIGUEL ANGEL LANASPA GARCIA; Fiscal Year: 2016
    ..He is currently the Division Head and Professor of Medicine at the University of Colorado Denver, Division of Renal Diseases and Hypertension...
  41. Optimal Selective Thyroid Hormone Analogs for Metabolic Syndrome
    John D Baxter; Fiscal Year: 2010
    ..Our strategy is to perform head to head comparisons of the existing and recently discovered ligands with distinct selectivity profiles and detailed ..
  42. Ralph A Nixon; Fiscal Year: 2014
    ..We propose to test hypotheses, based on preliminary data, that the head and rod domains of NFM regulate NF transport and trigger NF network formation along axons...
  43. Integrative Pathway Analysis of Epigenomic/transcriptional Alteration in HNSCC
    Joseph A Califano; Fiscal Year: 2010
    ..promoter hypomethylation frequently activate candidate proto-oncogenes and tumor specific cancer testes antigens in head and neck squamous cell carcinoma (HNSCC)...
  44. Jennifer S Stone; Fiscal Year: 2014
    ..A major cause of balance disorders is the loss of vestibular hair cells in the inner ear, which convert head movements into electrical signals that are sent to the brain via the vestibular nerve...
  45. Jac A Nickoloff; Fiscal Year: 2016
    ..of replication stress agents plus DDR inhibitors to enhance killing of breast, lung, pancreatic, colon, head and neck, and leukemic tumor cells...
  46. Roles of the mammalian CST complex in DNA replication and chromosome cohesion
    JASON AARON STEWART; Fiscal Year: 2013
    ..For these studies, I will be collaborating with Dr. Prasad Jallepalli, associate member and laboratory head at the Memorial Sloan-Kettering Cancer Center and an expert in chromosome cohesion and mitosis...
  47. Ribosomal Protein Gene Silencing in Neural Crest Stem Cells
    JOHNSON MING YU LIU; Fiscal Year: 2010
    ..population of stem cells that generates most of the bone, cartilage, connective and peripheral nerve tissue in the head in the developing embryo, and abnormalities in the neural crest can lead to craniofacial defects like cleft palate...
  48. Craig A Elmets; Fiscal Year: 2014
    ..They cause lung cancer and have been implicated in cancers of the head and neck, bladder and breast...
  49. Xiaobin Wang; Fiscal Year: 2014
    ..pregnancy loss (EPL), spontaneous abortion (SAB), and birth outcomes (gestational age, birth weight, length, and head circumference);(3) Preconception BMI and Micronutrients: including serum biomarkers of folate, B6, B12, cysteine, ..
  50. Phospholipid flip-flop in biogenic membranes
    Anant K Menon; Fiscal Year: 2013
    ..Unassisted flip-flop is extremely slow because of the energy barrier to taking the polar lipid head group through the hydrophobic interior of the membrane, yet lipids flip-flop rapidly across the ER membrane on a ..
  51. Twenty-first Annual Fanconi Anemia Research Fund Scientific Symposium
    Grover Bagby; Fiscal Year: 2009
    ..Acquired abnormalities of FA genes and FA gene expression have been reported in patients with sporadic malignancies of plasma cells, leukemia, head and neck cancer, lung cancer, and ovarian cancer.
  52. Jessica B Kendrick; Fiscal Year: 2015
    ..calcitriol) vitamin D supplementation improves vascular endothelial function in moderate to severe CKD in a direct head to head comparison...
  53. Rafael Bejar; Fiscal Year: 2016
    ..Ebert, include Dr. David Williams as a co-mentor, Dr. David Steensma as a clinical mentor, and Dr. Nancy Berliner, head of the Hematology division at Brigham and Women's Hospital, as a fourth member of his advisory committee...
  54. AMANDA MARIE LARRACUENTE; Fiscal Year: 2014
    ..their histones for sperm-specific protamines to aid in condensing the nucleus as it is re- shaped into the sperm head. To determine which chromatin components show aberrant localization in SD/SD+ testes, this proposal will ..
  55. Wei Xing Zong; Fiscal Year: 2016
    ..is associated with poorer prognosis in numerous advanced human cancers such as squamous cell carcinomas of lung, head and neck, and esophagus, as well as hepatocellular carcinoma and breast carcinoma...
  56. Plasminogen activators and NMDA after brain injury
    William M Armstead; Fiscal Year: 2012
    ..injury is the leading cause of death for infants and children and mortality is greatly increased in the presence of head injury...
  57. Mechanisms of cancer initiation by TRIM32
    Molly F Kulesz-Martin; Fiscal Year: 2012
    ..during epidermal carcinogenesis;3) explore the predictive value of Trim32/Piasy status in human skin and head and neck SCC prognosis as a basis for future strategies for molecular targeting of Trim32/Piasy interactions or ..
  58. Effect of Inducible Antioxidants on Hemoglobin Toxicity
    Raymond F Regan; Fiscal Year: 2010
    ..The information gained in this project may lead to new treatments for victims of hemorrhagic stroke and head trauma...
  59. Metagenomic profiling of oral polymicrobial flora in head and neck cancers
    Charis Eng; Fiscal Year: 2011
    ..Interestingly, the incidence of head and neck squamous cell carcinoma (HNSCC) has been shown to correlate with dental hygiene, which may suggest the ..
  60. Impact of Temperature Profile on Outcome After Traumatic Brain Injury
    Lori Kennedy Madden; Fiscal Year: 2013
    ..relative contribution of IMPACT variables (age, GCS motor score, pupillary reaction, hypoxia, hypotension, initial head CT classification, traumatic subarachnoid hemorrhage or epidural mass on CT, serum glucose, and serum hemoglobin) ..
  61. Novel non-invasive device for treatment of elevated intracranial pressures
    Keith G Lurie; Fiscal Year: 2011
    DESCRIPTION (provided by applicant): An estimated 1.6 million head injury occurs every year in the United States...
  62. Molecular Analysis of Alcohol Effects on Human Oral Epithelium Cells'Epigenome
    Alison Urvalek; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): In addition to tobacco, alcohol is the major risk factor for head and neck cancer...
  63. Lorraine J Gudas; Fiscal Year: 2014
    DESCRIPTION (provided by applicant): Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer worldwide [1]...
  64. Functional Genomics Approach to the Role of the JAK/STAT and MAPK Pathway in CBD
    Li Li; Fiscal Year: 2013
    ..With Dr. Maier, an expert in environmental sciences, genetics, genomics and bioinformatics, head of DEOHS, serving as the primary mentor, this program provides the candidate additional training in three essential ..
  65. Development and Validation of a Diagnostic Tool for Infant Head Injuries from Fal
    SUSAN SHEPS contact MARGULIES; Fiscal Year: 2010
    ..Unfortunately, falls are the leading cause of non-inflicted head injury in infants less than a year old, and are also the most common history provided by caretakers suspected of ..
  66. Prevention of Neck Injuries in Older Adults During Rear Motor Vehicle Collsions
    PAUL IVANCIC; Fiscal Year: 2009
    ..Some epidemiological studies have found head restraints to be ineffective, while others have reported an effectiveness rate reaching only 20% for neck injury ..
  67. MAGNESIUM SULFATE FOR NEUROPROTECTION AFTER BRAIN TRAUMA
    Nancy Temkin; Fiscal Year: 2004
    ..on our 20 years of experience in conducting clinical trials evaluating treatments for preventing seizures following head injury (Dilantin Prophylaxis of Post-traumatic Seizures...
  68. Faith Wurm Akin; Fiscal Year: 2015
    ..Dizziness and balance disorders are common symptoms associated with mTBI or head injury...
  69. Using Ecolog. Momentary Assess. To Examine Pain & Smoking In Head & Neck Cancer P
    CHO YAN LAM; Fiscal Year: 2010
    ..project is to study the relationships between pain, smoking motivation, and smoking cessation among patients with head and neck cancer...
  70. NAAG Peptidase Inhibitors for the Treatment of Traumatic Brain Injury
    Jia Zhou; Fiscal Year: 2009
    ..The annual economic cost to society for the care of head-injured patients has been estimated to exceed $25 billion...
  71. HEAD AND NECK CARCINOMA CELL KINETICS
    Marc Coltrera; Fiscal Year: 1993
    The overall goals of the project are to: a) study tumor cell kinetics in head and neck carcinomas using newly-developed monoclonal antibodies which identify proliferating cells in tissue sections and; b)develop a new classification system ..
  72. RANDOMIZED ADJUVANT THERAPY OF HEAD AND NECK CANCER
    Dong Shin; Fiscal Year: 2001
    ..III clinical trial designed to study adjuvant biologic therapy, using biomarkers, for patients with stage III/IV head and neck cancer...
  73. SYSTEMS ANALYSIS OF HEAD STABILIZATION
    Barry Peterson; Fiscal Year: 1999
    Proper stabilization of the head is essential for humans to carry out many of the essential activities of daily living...
  74. VIEWING DISTANCE AND COMPENSATORY MOVEMENTS IN FALLS
    GEOFFREY BUSH; Fiscal Year: 2001
    ..is to understand how the brain incorporates viewing distance into a coordinated motor response of the eyes and head during vertical accelerations...
  75. AN ECM SCAFFOLD FOR HEAD AND NECK REPAIR
    Alan Spievack; Fiscal Year: 2001
    ..ECM) bioscaffold derived from the urinary bladder submucosa (UBS) for tissue engineering applications in the head and neck. The three specific aims of our Phase I study were successfully completed...
  76. MOLECULAR REGULATION OF SMOOTH MUSCLE ACTOMYOSIN
    Mitsuo Ikebe; Fiscal Year: 2004
    ..Our hypothesis is that phosphorylation of RLC changes a conformation that attenuates an inter-head interaction at RLC binding domain, and this change is transmitted to the motor domain via a long -helix shaft of ..
  77. Vestibular Compensation During Volitional Head Movements
    SHAWN NEWLANDS; Fiscal Year: 2004
    ..Preliminary studies have investigated the role played by volition in compensatory ocular responses during head movement by analyzing unrestrained eye and head saccadic movements (head-free gaze shifts) before and after ..