ankle

Summary

Summary: The region of the lower limb between the FOOT and the LEG.

Top Publications

  1. ncbi Ultrasound improves the success rate of a tibial nerve block at the ankle
    Kirsten E Redborg
    Department of Anesthesiology, Dartmouth Medical School, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Reg Anesth Pain Med 34:256-60. 2009
  2. ncbi Validity, reproducibility, and clinical significance of noninvasive brachial-ankle pulse wave velocity measurement
    Akira Yamashina
    Second Department of Internal Medicine, Tokyo Medical University, Japan
    Hypertens Res 25:359-64. 2002
  3. pmc Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis
    F G R Fowkes
    JAMA 300:197-208. 2008
  4. ncbi Powered ankle-foot prosthesis to assist level-ground and stair-descent gaits
    Samuel Au
    MIT Media Laboratory, 20 Ames Street, Cambridge, MA 02139, USA
    Neural Netw 21:654-66. 2008
  5. ncbi Ankle-brachial blood pressure index predicts all-cause and cardiovascular mortality in hemodialysis patients
    Kumeo Ono
    Kan etsu Chuo Hospital, Maebashi, Gunma, Japan
    J Am Soc Nephrol 14:1591-8. 2003
  6. ncbi Brachial-ankle pulse wave velocity as a marker of atherosclerotic vascular damage and cardiovascular risk
    Akira Yamashina
    Second Department of Internal Medicine, Tokyo Medical University, Tokyo, Japan
    Hypertens Res 26:615-22. 2003
  7. ncbi Ankle-arm index as a predictor of cardiovascular disease and mortality in the Cardiovascular Health Study. The Cardiovascular Health Study Group
    A B Newman
    University of Pittsburgh, Pittsburgh, PA, USA
    Arterioscler Thromb Vasc Biol 19:538-45. 1999
  8. ncbi Brachial-ankle pulse wave velocity: an index of central arterial stiffness?
    J Sugawara
    Institute for Human Science and Bioengineering, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    J Hum Hypertens 19:401-6. 2005
  9. ncbi Foot and ankle strength, range of motion, posture, and deformity are associated with balance and functional ability in older adults
    Martin J Spink
    Musculoskeletal Research Centre, Department of Podiatry, La Trobe University, Bundoora, Australia
    Arch Phys Med Rehabil 92:68-75. 2011
  10. ncbi Impact of brachial-ankle pulse wave velocity and ankle-brachial blood pressure index on mortality in hemodialysis patients
    Tokuyuki Kitahara
    Department of Medicine and Clinical Science, Gunma Graduate School of Medicine, Maebashi, Japan
    Am J Kidney Dis 46:688-96. 2005

Detail Information

Publications284 found, 100 shown here

  1. ncbi Ultrasound improves the success rate of a tibial nerve block at the ankle
    Kirsten E Redborg
    Department of Anesthesiology, Dartmouth Medical School, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Reg Anesth Pain Med 34:256-60. 2009
    ..there exists little evidence-based medicine evaluating different techniques for blocking the tibial nerve at the ankle. We hypothesized that an ultrasound (US)-guided tibial nerve block at the ankle would prove more successful than a ..
  2. ncbi Validity, reproducibility, and clinical significance of noninvasive brachial-ankle pulse wave velocity measurement
    Akira Yamashina
    Second Department of Internal Medicine, Tokyo Medical University, Japan
    Hypertens Res 25:359-64. 2002
    The present study was conducted to evaluate the validity and reproducibility of noninvasive brachial-ankle pulse wave velocity (baPWV) measurements and to examine the alteration of baPWV in patients with coronary artery disease (CAD)...
  3. pmc Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis
    F G R Fowkes
    JAMA 300:197-208. 2008
    Prediction models to identify healthy individuals at high risk of cardiovascular disease have limited accuracy. A low ankle brachial index (ABI) is an indicator of atherosclerosis and has the potential to improve prediction.
  4. ncbi Powered ankle-foot prosthesis to assist level-ground and stair-descent gaits
    Samuel Au
    MIT Media Laboratory, 20 Ames Street, Cambridge, MA 02139, USA
    Neural Netw 21:654-66. 2008
    The human ankle varies impedance and delivers net positive work during the stance period of walking...
  5. ncbi Ankle-brachial blood pressure index predicts all-cause and cardiovascular mortality in hemodialysis patients
    Kumeo Ono
    Kan etsu Chuo Hospital, Maebashi, Gunma, Japan
    J Am Soc Nephrol 14:1591-8. 2003
    A reduction in ankle-brachial BP index (ABPI) is associated with generalized atherosclerotic diseases and predicts cardiovascular mortality and morbidity in several patient populations...
  6. ncbi Brachial-ankle pulse wave velocity as a marker of atherosclerotic vascular damage and cardiovascular risk
    Akira Yamashina
    Second Department of Internal Medicine, Tokyo Medical University, Tokyo, Japan
    Hypertens Res 26:615-22. 2003
    The measurement of brachial-ankle pulse wave velocity (baPWV) is simple and applicable for general population studies...
  7. ncbi Ankle-arm index as a predictor of cardiovascular disease and mortality in the Cardiovascular Health Study. The Cardiovascular Health Study Group
    A B Newman
    University of Pittsburgh, Pittsburgh, PA, USA
    Arterioscler Thromb Vasc Biol 19:538-45. 1999
    Peripheral arterial disease (PAD) in the legs, measured noninvasively by the ankle-arm index (AAI) is associated with clinically manifest cardiovascular disease (CVD) and its risk factors...
  8. ncbi Brachial-ankle pulse wave velocity: an index of central arterial stiffness?
    J Sugawara
    Institute for Human Science and Bioengineering, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    J Hum Hypertens 19:401-6. 2005
    Brachial-ankle pulse wave velocity (baPWV) is a promising technique to assess arterial stiffness conveniently. However, it is not known whether baPWV is associated with well-established indices of central arterial stiffness...
  9. ncbi Foot and ankle strength, range of motion, posture, and deformity are associated with balance and functional ability in older adults
    Martin J Spink
    Musculoskeletal Research Centre, Department of Podiatry, La Trobe University, Bundoora, Australia
    Arch Phys Med Rehabil 92:68-75. 2011
    To determine the extent to which measures of foot and ankle strength, range of motion, posture, and deformity are associated with performance in a battery of balance and functional ability tests in older adults.
  10. ncbi Impact of brachial-ankle pulse wave velocity and ankle-brachial blood pressure index on mortality in hemodialysis patients
    Tokuyuki Kitahara
    Department of Medicine and Clinical Science, Gunma Graduate School of Medicine, Maebashi, Japan
    Am J Kidney Dis 46:688-96. 2005
    Pulse wave velocity (PWV) and ankle-brachial blood pressure index (ABPI) are markers for atherosclerosis, and each predicts mortality in patients undergoing hemodialysis...
  11. ncbi Clinical significance and reproducibility of new arterial distensibility index
    Takuro Kubozono
    Department of Cardiovascular, Respiratory and Metabolic Medicine, Graduate School of Medicine, Kagoshima University, Japan
    Circ J 71:89-94. 2007
    The brachial-ankle pulse wave velocity (baPWV) is used to evaluate the degree of atherosclerosis and arterial distensibility, but its major limitation is that it is affected by changes in blood pressure (BP) during measurement...
  12. ncbi Effect of ezetimibe monotherapy on lipid metabolism and arterial stiffness assessed by cardio-ankle vascular index in type 2 diabetic patients
    Yoh Miyashita
    Departments of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University, 564 1 Shimoshizu, Chiba, Japan
    J Atheroscler Thromb 17:1070-6. 2010
    ..High cholesterol absorption in the small intestine has been proposed to be a risk factor of atherosclerosis. In this study, we evaluated the effect of ezetimibe monotherapy on arterial stiffness in type 2 diabetic patients...
  13. ncbi Correlation between brachial-ankle pulse wave velocity and arterial compliance and cardiovascular risk factors in elderly patients with arteriosclerosis
    Baoying Li
    Department of Geriatrics, Qi Lu Hospital of Shandong University, Jinan, PR China
    Hypertens Res 29:309-14. 2006
    ..of this study was to investigate an association between major cardiovascular risk factors and each of brachial-ankle pulse wave velocity (baPWV), ankle-brachial index (ABI), capacitive arterial compliance (C1), and oscillatory ..
  14. ncbi Influence of blood pressure on cardio-ankle vascular index (CAVI) examined based on percentage change during general anesthesia
    Barkhwa Kim
    Department of Dental Anesthesiology, Nihon University School of Dentistry, Tokyo, Japan
    Hypertens Res 34:779-83. 2011
    Cardio-ankle vascular index (CAVI) and brachial-ankle pulse wave velocity (baPWV) are non-invasive methods for estimating arterial distensibility...
  15. pmc Patient specific ankle-foot orthoses using rapid prototyping
    Constantinos Mavroidis
    Department of Mechanical and Industrial Engineering, Northeastern University, Boston, MA 02115, USA
    J Neuroeng Rehabil 8:1. 2011
    ..A computerized technique for fabricating patient-specific orthotic devices has the potential to provide excellent comfort and allow for changes in the standard design to meet the specific needs of each patient...
  16. ncbi Are stance ankle plantar flexor muscles necessary to generate propulsive force during human gait initiation?
    V Michel
    Laboratoire de Physiologie du Mouvement, INSERM U483, Universite Paris Sud, Bat 441, Orsay, France
    Neurosci Lett 325:139-43. 2002
    ..forward propulsive force (PF) during gait initiation resulted mainly from the electromyogram activity of stance ankle plantar flexor muscles (APF) which 'push' on the ground as is generally claimed in the literature...
  17. ncbi Ankle--brachial index, vascular calcifications and mortality in dialysis patients
    Teresa Adragao
    Diaverum, Unidade do Estoril, Portugal
    Nephrol Dial Transplant 27:318-25. 2012
    The ankle-brachial index (ABI) is a noninvasive method to evaluate peripheral artery disease (PAD). ABI <0.9 diagnoses PAD; ABI >1.3 is a false negative caused by noncompressible arteries...
  18. ncbi Reverse correlation between ankle-brachial index and left ventricular hypertrophy in patients on maintenance haemodialysis
    Wencheng Fu
    Department of Nephrology, Center of Kidney Disease, Changzheng Hospital, Second Military Medical University, Shanghai, China
    Nephrology (Carlton) 11:9-14. 2006
    ..b>Ankle-brachial index (ABI) has been recently demonstrated to be a predictor for all-cause and cardiovascular mortality ..
  19. ncbi The human ankle during walking: implications for design of biomimetic ankle prostheses
    Andrew H Hansen
    Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    J Biomech 37:1467-74. 2004
    The non-disabled human ankle joint was examined during walking in an attempt to determine overall system characteristics for use in the design of ankle prostheses...
  20. ncbi Cardio-ankle vascular index is superior to brachial-ankle pulse wave velocity as an index of arterial stiffness
    Akira Takaki
    Takaki Medical Clinic, 3198 6, Kume, Shunan 745 0801, Japan
    Hypertens Res 31:1347-55. 2008
    Both cardio-ankle vascular index (CAVI) and brachial-ankle pulse wave velocity (baPWV) are noninvasive methods to estimate arterial stiffness...
  21. ncbi A novel blood pressure-independent arterial wall stiffness parameter; cardio-ankle vascular index (CAVI)
    Kohji Shirai
    Internal Medicine, Sakura Hospital, Medical Center, Toho University, 564 1 Shimoshizu, Sakura shi, Chiba 285 8741, Japan
    J Atheroscler Thromb 13:101-7. 2006
    To measure the stiffness of the aorta, femoral artery and tibial artery noninvasively, cardio-ankle vascular index (CAVI) which is independent of blood pressure was developed...
  22. ncbi Control of a powered ankle-foot prosthesis based on a neuromuscular model
    Michael F Eilenberg
    Mechanical Engineering Department, Massachusetts Institute of Technology MIT, Cambridge, MA, USA
    IEEE Trans Neural Syst Rehabil Eng 18:164-73. 2010
    Control schemes for powered ankle-foot prostheses rely upon fixed torque-ankle state relationships obtained from measurements of intact humans walking at target speeds and across known terrains...
  23. ncbi Ethnic differences in peripheral arterial disease in the NHLBI Genetic Epidemiology Network of Arteriopathy (GENOA) study
    Iftikhar J Kullo
    Division of Cardiovascular Diseases, Mayo Clinic and Foundation, 200 First Street Southwest, Rochester, MN 55905, USA
    Vasc Med 8:237-42. 2003
    ..We compared the distribution of the ankle-brachial index (ABI), a measure of PAD, between African Americans and non-Hispanic white individuals...
  24. ncbi Ankle-brachial index and extent of atherothrombosis in 8891 patients with or at risk of vascular disease: results of the international AGATHA study
    F Gerald R Fowkes
    Department of Public Health Sciences, Wolfson Unit for the Prevention of Peripheral Vascular Diseases, University of Edinburgh, Edinburgh EH8 9AG, UK
    Eur Heart J 27:1861-7. 2006
    ..a Global Atherothrombosis Assessment) was designed to assess the extent of atherothrombosis and the use of the ankle-brachial index (ABI) in vascular patients...
  25. ncbi Utility and barriers to performance of the ankle-brachial index in primary care practice
    Emile R Mohler
    University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Vasc Med 9:253-60. 2004
    ..The PARTNERS Program implemented the ankle-brachial index (ABI) measurement in primary care outpatient clinics in order to model practical dissemination of ..
  26. ncbi Infectious and healing complications after elective orthopaedic foot and ankle surgery during tumor necrosis factor-alpha inhibition therapy
    Christopher Bibbo
    Department of Orthopaedic Surgery, Marshfield Clinic, WI 54449, USA
    Foot Ankle Int 25:331-5. 2004
    ..This study analyzed the risk of healing/infectious complications in patients undergoing elective foot and ankle surgery while being treated with TNF-alpha inhibitors etanercept and infliximab.
  27. ncbi Association of ankle-brachial index and plaques in the carotid and femoral arteries with cardiovascular events and total mortality in a population-based study with 13 years of follow-up
    Claudia Lamina
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
    Eur Heart J 27:2580-7. 2006
    ..We prospectively examined the association of the ankle-brachial index (ABI) and arterial plaques in carotid and femoral arteries with incident myocardial infarctions (..
  28. ncbi Prospective, randomized, multi-center feasibility trial of rhPDGF-BB versus autologous bone graft in a foot and ankle fusion model
    Christopher W DiGiovanni
    University Orthopaedics, Inc, 100 Butler Dr, Providence, RI 02906, USA
    Foot Ankle Int 32:344-54. 2011
    ..of this prospective, controlled, randomized, multi-center feasibility clinical trial was to compare the safety and efficacy of this biosynthetic bone graft substitute (Augment™ Bone Graft) to ABG during ankle and hindfoot fusion.
  29. ncbi Effects of telmisartan on arterial stiffness assessed by the cardio-ankle vascular index in hypertensive patients
    Kenichiro Kinouchi
    Department of Endocrinology, Metabolism, and Nephrology, Keio University School of Medicine, Tokyo, Japan
    Kidney Blood Press Res 33:304-12. 2010
    This study was conducted to determine the effect of telmisartan on the cardio-ankle vascular index (CAVI), a novel blood pressure (BP)-independent marker for arterial stiffness in hypertensive patients.
  30. ncbi Tumors of the foot and ankle: analysis of 196 cases
    H M Ozdemir
    Ankara University School of Medicine, Department of Orthopedics and Traumatology, Turkey
    J Foot Ankle Surg 36:403-8. 1997
    A retrospective assessment was performed on 196 tumors of the foot and ankle [out of 1786 bone and soft tissue tumor cases, (10...
  31. ncbi Short-term effects of functional electrical stimulation on motor-evoked potentials in ankle flexor and extensor muscles
    Aiko Kido Thompson
    Centre for Neuroscience, 513 Heritage Medical Research Centre, University of Alberta, T6G 2S2 Edmonton, Alberta, Canada
    Exp Brain Res 159:491-500. 2004
    ..electrical stimulation of the common peroneal (CP) nerve during walking on motor-evoked potentials (MEPs) in the ankle flexors and extensors in healthy subjects...
  32. ncbi Modulation of soleus H-reflex by presynaptic spinal mechanisms during varying surface and ankle brace conditions
    J M Sefton
    Biodynamics Research Laboratory, Department of Kinesiology, The University of North Carolina, Charlotte NC 28223, USA
    Neurophysiol Clin 37:15-21. 2007
    ..The intent of this study was to evaluate changes in PRD of the soleus H-reflex during single-leg stance under varying stability conditions...
  33. ncbi MR imaging of entrapment neuropathies of the lower extremity. Part 2. The knee, leg, ankle, and foot
    Andrea Donovan
    Department of Radiology, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, ON, Canada
    Radiographics 30:1001-19. 2010
    Entrapment neuropathies of the knee, leg, ankle, and foot are often underdiagnosed, as the results of clinical examination and electrophysiologic evaluation are not always reliable...
  34. ncbi The inter-arm blood pressure difference and peripheral vascular disease: cross-sectional study
    Christopher E Clark
    Primary Care Research Group, Institute of Health and Social Care Research, Peninsula Medical School, St Luke s Campus, Exeter, Devon, UK
    Fam Pract 24:420-6. 2007
    ..Knowledge of its prevalence and importance in the accurate measurement of BP is poor, representing a source of error. Current hypertension guidelines do not emphasize this...
  35. ncbi Noninvasive indices of arterial stiffness in hemodialysis patients
    Kiyo Ueyama
    Department of Cardiovascular, Respiratory and Metabolic Medicine, Graduate School of Medicine, Kagoshima University, Kagoshima 890 8520, Japan
    Hypertens Res 32:716-20. 2009
    The purpose of this study was to evaluate the validity of brachial-ankle pulse wave velocity (baPWV) and the cardio-ankle vascular index (CAVI) as measures of arterial stiffness in hemodialysis (HD) patients...
  36. ncbi Ankle brachial index as a marker of atherosclerosis in Chinese patients with high cardiovascular risk
    Buaijiaer Hasimu
    Heart, Lung and Blood Vessel Center, Tongji University, Shanghai, P R China
    Hypertens Res 29:23-8. 2006
    ..and risk factor profile of peripheral arterial disease (PAD), we evaluated the clinical significance of the ankle brachial index (ABI) as an indicator of PAD in Chinese patients at high cardiovascular (CV) risk...
  37. ncbi Improvement of cardio-ankle vascular index by glimepiride in type 2 diabetic patients
    D Nagayama
    Center of Diabetes, Endocrine and Metabolism, Sakura Hospital, School of Medicine Toho University, Sakura City, Chiba, Japan
    Int J Clin Pract 64:1796-801. 2010
    ..We investigated the efficacy of glimepiride in improving arterial stiffness assessed by cardio-ankle vascular index (CAVI) in type 2 diabetic patients, compared with glibenclamide, a conventional SU.
  38. ncbi Ankle brachial pressure index and carotid intima-media thickness as atherosclerosis markers in Japanese diabetics
    Chisa Hayashi
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Diabetes Res Clin Pract 66:269-75. 2004
    The aim of this study was to assess the clinical significance of ankle brachial pressure index (ABI) and carotid intima-media thickness (IMT) in Japanese patients with type 2 diabetes...
  39. ncbi Cardio-ankle vascular index could reflect plaque burden in the coronary artery
    Shigeo Horinaka
    Dokkyo Medical University, Department of Hypertension and Cardiorenal Medicine, Mibu, Tochigi, Japan
    Angiology 62:401-8. 2011
    Cardio-ankle vascular index (CAVI) using the volume plethysmographic method is a noninvasive atherosclerotic indicator which is not influenced by blood pressure...
  40. ncbi Reliability and validity of the foot and ankle outcome score: a validation study from Iran
    Hossein Negahban
    Department of Physical Therapy, School of Rehabilitation Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
    Clin Rheumatol 29:479-86. 2010
    The aims of this study were to culturally adapt and validate the Persian version of Foot and Ankle Outcome Score (FAOS) and present data on its psychometric properties for patients with different foot and ankle problems...
  41. ncbi Results of an Internet survey determining the most frequently used ankle scores by AOFAS members
    Johnny T C Lau
    Orthopaedic Surgery, UHN Toronto Western Hospital, Toronto, Ontario, Canada
    Foot Ankle Int 26:479-82. 2005
    With technological advances in ankle arthroplasty, there has been parallel development in the outcome instruments used to assess the results of surgery...
  42. ncbi Re-weighting of somatosensory inputs from the foot and the ankle for controlling posture during quiet standing following trunk extensor muscles fatigue
    Nicolas Vuillerme
    Laboratoire TIMC IMAG, Faculte de Medecine, UMR UJF CNRS 5525, 38706, La Tronche Cedex, France
    Exp Brain Res 183:323-7. 2007
    ..fatigue on postural control during quiet standing under different somatosensory conditions from the foot and the ankle. With this aim, 20 young healthy adults were asked to stand as immobile as possible in two conditions of No ..
  43. ncbi Risk factors for declining ankle-brachial index in men and women 65 years or older: the Cardiovascular Health Study
    Margaret Kennedy
    Department of Medicine, University of Vermont, Burlington, USA
    Arch Intern Med 165:1896-902. 2005
    An ankle-brachial index (ABI) of less than 0.9 is a noninvasive measure of lower extremity arterial disease and a predictor of cardiovascular events...
  44. ncbi Cardio-ankle vascular index (CAVI) as a novel indicator of arterial stiffness: theory, evidence and perspectives
    Kohji Shirai
    Internal Medicine, Sakura Hospital, School of Medicine, Toho University
    J Atheroscler Thromb 18:924-38. 2011
    The cardio-ankle vascular index (CAVI) is a new index of the overall stiffness of the artery from the origin of the aorta to the ankle. The most conspicuous feature of CAVI is its independence of blood pressure at the time of measurement...
  45. ncbi Viscerally obese women with normal body weight have greater brachial-ankle pulse wave velocity than nonviscerally obese women with excessive body weight
    Ji Won Lee
    Department of Family Medicine, Yonsei University, College of Medicine, Yongdong Severance Hospital, Kangnam, Korea
    Clin Endocrinol (Oxf) 66:572-8. 2007
    To confirm the association of visceral obesity and brachial-ankle pulse wave velocity (baPWV) and to compare metabolic indices and baPWV between individuals who have normal body weight but are viscerally obese and individuals with ..
  46. ncbi Ankle brachial index <0.9 underestimates the prevalence of peripheral artery occlusive disease assessed with whole-body magnetic resonance angiography in the elderly
    J Wikstrom
    Department of Radiology and Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden
    Acta Radiol 49:143-9. 2008
    ..Whole-body magnetic resonance angiography (WBMRA) permits noninvasive vascular assessment, which can be utilized in epidemiological studies...
  47. ncbi The MOXFQ patient-reported questionnaire: assessment of data quality, reliability and validity in relation to foot and ankle surgery
    J Dawson
    The Department of Public Health, University of Oxford, Old Road Campus, Roosevelt Drive, Headington, Oxford OX3 7LF, United Kingdom
    Foot (Edinb) 21:92-102. 2011
    ..the Manchester-Oxford Foot Questionnaire (MOXFQ) is here evaluated for use with different regions of the foot and ankle. The study recruited 671 consecutive patients (87.8% of those eligible), mean age 52...
  48. pmc Periodontal disease and atherosclerosis from the viewpoint of the relationship between community periodontal index of treatment needs and brachial-ankle pulse wave velocity
    Koichi Miyaki
    Department of Health Informatics, Kyoto University School of Public Health, Kyoto, Japan
    BMC Public Health 6:131. 2006
    ..However, the relationship between periodontal disease and atherosclerosis has not been fully elucidated. This study aimed to assess the effects of periodontal disease on atherosclerosis...
  49. ncbi A new method for evaluating ankle foot orthosis characteristics: BRUCE
    D J J Bregman
    MOVE Institute for Human Movement Research, VU University Medical Center, Amsterdam, The Netherlands
    Gait Posture 30:144-9. 2009
    The mechanical characteristics of ankle foot orthoses (AFOs), such as the stiffness and neutral angle around the ankle and metatarsal-phalangeal (MTP) joints, are rarely quantified...
  50. ncbi The relation between ankle impairments and gait velocity and symmetry in people with stroke
    Pei Yi Lin
    Institute and Faculty of Physical Therapy, National Yang Ming University, Taipei, Taiwan
    Arch Phys Med Rehabil 87:562-8. 2006
    To identify the most important factor among the ankle impairments on gait velocity and symmetry in stroke patients.
  51. ncbi Robot assisted gait training with active leg exoskeleton (ALEX)
    Sai K Banala
    Department of Mechanical Engineering, University of Delaware, Newark, DE 19716, USA
    IEEE Trans Neural Syst Rehabil Eng 17:2-8. 2009
    ..The force-field controller achieves this paradigm by effectively applying forces at the ankle of the subject through actuators on the hip and knee joints...
  52. ncbi Fresh-frozen structural allografts in the foot and ankle
    Mark S Myerson
    Union Memorial Hospital, Baltimore, Maryland, USA
    J Bone Joint Surg Am 87:113-20. 2005
    ..of this study was to review the results of using structural fresh-frozen femoral head allografts in foot and ankle procedures...
  53. ncbi Association of cardio-ankle vascular index with physical fitness and cognitive symptoms in aging Finnish firefighters
    H Lindholm
    Finnish Institute of Occupational Health, Topeliuksenkatu 41a A, 00250, Helsinki, Finland
    Int Arch Occup Environ Health 85:397-403. 2012
    ..The aim of this study was to analyze associations between aerobic fitness, cognitive symptoms and cardio-ankle vascular index (CAVI) as a measure for AS among Finnish firefighters.
  54. ncbi Determinants of the second derivative of the finger photoplethysmogram and brachial-ankle pulse-wave velocity: the Ohasama study
    Junichiro Hashimoto
    Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Science and Medicine, Sendai, Japan
    Am J Hypertens 18:477-85. 2005
    ..We examined different characteristics of the second derivative of the finger photoplethysmogram (SDPTG) and brachial-ankle pulse wave velocity (BAPWV) for assessing arterial function in a large general population, along with the ..
  55. pmc Development and reliability of a standard rating system for outcome measurement of foot and ankle disorders II: interclinician and intraclinician reliability and validity of the newly established standard rating scales and Japanese Orthopaedic Association
    Hisateru Niki
    Department of Orthopaedic Surgery, St Marianna University School of Medicine, 2 16 1 Sugao, Miyamae ku, Kanagawa 216 8511, Japan
    J Orthop Sci 10:466-74. 2005
    ..reliability of (1) the Japanese Society of Surgery of the Foot (JSSF) standard rating system for four sites [ankle-hindfoot (AH), midfoot (MF), hallux (HL), and lesser toe (LT)] and the rheumatoid arthritis (RA) foot and ankle ..
  56. ncbi The effect of casting combined with stretching on passive ankle dorsiflexion in adults with traumatic head injuries
    A M Moseley
    Brain Injury Rehabilitation Unit, Liverpool Health Service, Liverpool, New South Wales, Australia
    Phys Ther 77:240-7; discussion 248-59. 1997
    b>Ankle plantar-flexion contractures are a common problem following traumatic head injury...
  57. ncbi Utility of automated brachial ankle pulse wave velocity measurements in hypertensive patients
    Masanori Munakata
    Division of Hypertension and Cardiology, Tohoku Rosai Hospital, 3 21 Dainohara 4, Aobaku, Sendai 981 8563, Japan
    Am J Hypertens 16:653-7. 2003
    We examined whether pulse wave velocity (PWV), determined by brachial ankle arterial pressure wave measurements, using a newly developed, fully automated device could be a surrogate measure for carotid femoral PWV.
  58. pmc Voluntary activation of ankle muscles is accompanied by subcortical facilitation of their antagonists
    Svend S Geertsen
    Department of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
    J Physiol 588:2391-402. 2010
    ..During and just prior to dorsiflexion of the ankle, soleus motoneurones are thus inhibited as evidenced by a depression of the soleus H-reflex...
  59. ncbi A clinical prediction model for the presence of peripheral arterial disease--the benefit of screening individuals before initiation of measurement of the ankle-brachial index: an observational study
    Bianca L W Bendermacher
    Department of Surgery, Division of Vascular Surgery, Atrium Medical Centre, Heerlen, The Netherlands
    Vasc Med 12:5-11. 2007
    Measurement of the ankle-brachial index (ABI) can provide important information about the presence of subclinical atherosclerosis. Performing the ABI in the overall population is not feasible, but it can be used in a selected population...
  60. ncbi Aspirin for prevention of cardiovascular events in a general population screened for a low ankle brachial index: a randomized controlled trial
    F Gerald R Fowkes
    Centre for Population Health Sciences, University of Edinburgh, Scotland
    JAMA 303:841-8. 2010
    A low ankle brachial index (ABI) indicates atherosclerosis and an increased risk of cardiovascular and cerebrovascular events...
  61. ncbi Relationship of high and low ankle brachial index to all-cause and cardiovascular disease mortality: the Strong Heart Study
    Helaine E Resnick
    Department of Epidemiology, MedStar Research Institute, Hyattsville, Md 20873, USA
    Circulation 109:733-9. 2004
    The associations of low (<0.90) and high (>1.40) ankle brachial index (ABI) with risk of all-cause and cardiovascular disease (CVD) mortality have not been examined in a population-based setting.
  62. ncbi Non-invasive brain stimulation enhances fine motor control of the hemiparetic ankle: implications for rehabilitation
    Sangeetha Madhavan
    Department of Physical Therapy, University of Illinois, 1919 W Taylor St, Chicago, IL 60612, USA
    Exp Brain Res 209:9-17. 2011
    ..Can stroke patients improve voluntary control of their paretic ankle by practising a visuo-motor ankle-tracking task? 2...
  63. ncbi Availability of cardio-ankle vascular index (CAVI) as a screening tool for atherosclerosis
    Koichiro Kadota
    Department of General Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan
    Circ J 72:304-8. 2008
    A novel index, the cardio-ankle vascular index (CAVI), which reflects the stiffness of the aorta, femoral artery, and tibial artery, was recently developed by measuring brachial - ankle pulse wave velocity and blood pressure.
  64. ncbi Effect of aliskiren addition to amlodipine on ankle edema in hypertensive patients: a three-way crossover study
    Roberto Fogari
    Clinica Medica II, University of Pavia, Centro Ipertensione e Fisiopatologia Cardiovascolare, Department of Internal Medicine and Therapeutics, Pavia, Italy
    Expert Opin Pharmacother 12:1351-8. 2011
    The aim of this study was to assess the effect of aliskiren and amlopidine on ankle-foot volume (AFV) and pretibial subcutaneous tissue pressure (PSTP).
  65. ncbi Comparison of atherosclerotic indicators between cardio ankle vascular index and brachial ankle pulse wave velocity
    Shigeo Horinaka
    Department of Hypertension and Cardiorenal Medicine, Dokkyo Medical University, Mibu, Tochigi 321 0293, Japan
    Angiology 60:468-76. 2009
    ..The brachial ankle pulse wave velocity and cardio ankle vascular index are used for estimating the extent of atherosclerosis...
  66. ncbi The effects of adding mass to the legs on the energetics and biomechanics of walking
    Raymond C Browning
    Department of Integrative Physiology, University of Colorado, Boulder, CO 80262, USA
    Med Sci Sports Exerc 39:515-25. 2007
    ....
  67. ncbi Brain activity during ankle proprioceptive stimulation predicts balance performance in young and older adults
    Daniel J Goble
    Motor Control Laboratory, Research Center for Movement Control and Neuroplasticity, Department of Biomedical Kinesiology, Katholieke Universiteit Leuven, 3000 Leuven, Belgium
    J Neurosci 31:16344-52. 2011
    Proprioceptive information from the foot/ankle provides important information regarding body sway for balance control, especially in situations where visual information is degraded or absent...
  68. ncbi Using ankle-brachial index to detect peripheral arterial disease: prevalence and associated risk factors in a random population sample
    Julio A Carbayo
    Medical Corps, 14th Fighter Wing Air Base, Albacete, Spain
    Nutr Metab Cardiovasc Dis 17:41-9. 2007
    The ankle-brachial index (ABI) is being used increasingly to diagnose peripheral arterial disease (PAD) that predicts cardiovascular morbidity and mortality...
  69. ncbi Volume of ankle dorsiflexors and plantar flexors determined with stereological techniques
    P Gadeberg
    Department of Neurology and Magnetic Resonance Research Center, Aarhus University Hospital, 8000 Aarhus C, Denmark
    J Appl Physiol (1985) 86:1670-5. 1999
    ..Power [peak torque (PT)] of the ankle dorsiflexors and plantar flexors was estimated by using isokinetic dynamometry. Dorsiflexor volume (r2 = 0...
  70. ncbi Endothelial dysfunction, intima-media thickness, ankle-brachial pressure index, and pulse pressure in young post-myocardial infarction patients with various expressions of classical risk factors
    Barbara Erzen
    Department of Vascular Disease, University Medical Centre, Zaloska 2, 1000 Ljubljana, Slovenia
    Heart Vessels 22:215-22. 2007
    ..markers of arterial function and morphology, such as endothelial dysfunction (ED), intima-media thickness (IMT), ankle-brachial pressure index (ABPI), and pulse pressure (PP) may be useful in coronary risk estimation...
  71. ncbi Partial denervation of ankle extensors prior to spinalization in cats impacts the expression of locomotion and the phasic modulation of reflexes
    A Frigon
    Department of Physiology, Universite de Montreal, Station Centre Ville, Montreal, Quebec, Canada H3C 3J7
    Neuroscience 158:1675-90. 2009
    ..Reflexes, evoked by stimulating the left tibial nerve at the ankle, the electromyography of several hindlimb muscles, and kinematics were recorded during locomotion before and after ..
  72. ncbi Precision and accuracy of an ankle-worn accelerometer-based pedometer in step counting and energy expenditure
    Randal C Foster
    Endocrine Research Unit, Division of Endocrinology, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Prev Med 41:778-83. 2005
    ..In this paper, we investigate the precision and accuracy of an ankle-worn dual-axis accelerometer (Stepwatch) and investigate its potential application as a predictor of energy ..
  73. ncbi Intrinsic contribution of gender and ethnicity to normal ankle-brachial index values: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Victor Aboyans
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA, USA
    J Vasc Surg 45:319-27. 2007
    ..These studies based their PAD definition on an ankle-brachial index (ABI) <0.90...
  74. ncbi Effects of an ankle-foot orthosis on spatiotemporal parameters and energy cost of hemiparetic gait
    Marco Franceschini
    Department of Geriatrics and Rehabilitation, Hospital of Parma, Italy
    Clin Rehabil 17:368-72. 2003
    To assess the effect of an ankle-foot orthosis on the gait and energy parameters of walking in chronic hemiparetic subjects.
  75. ncbi Relationship between cardio-ankle vascular index (CAVI) and carotid atherosclerosis in patients with essential hypertension
    Takafumi Okura
    Department of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine, Toon, Japan
    Hypertens Res 30:335-40. 2007
    ..Brachial-ankle PWV (baPWV) has been developed as a more convenient assessment of arterial stiffness...
  76. ncbi Differences between trunk sway characteristics on a foam support surface and on the Equitest ankle-sway-referenced support surface
    J H J Allum
    Department of ORL, University Hospital, Basel, Switzerland
    Gait Posture 16:264-70. 2002
    ..One technique often used for this purpose is to reduce the efficacy of ankle proprioceptive inputs on sway...
  77. ncbi A high ankle-brachial index is associated with increased cardiovascular disease morbidity and lower quality of life
    Matthew A Allison
    Department of Family and Preventive Medicine, University of California San Diego, California, USA
    J Am Coll Cardiol 51:1292-8. 2008
    The purpose of this study is to determine if an ankle-brachial index (ABI) >or=1.40 is associated with reduced quality of life (QoL).
  78. pmc Association of polymorphisms in NOS3 with the ankle-brachial index in hypertensive adults
    Iftikhar J Kullo
    Divisions of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Atherosclerosis 196:905-12. 2008
    We investigated the association of 14 polymorphisms in the endothelial nitric oxide synthase gene (NOS3) with ankle brachial index (ABI) in non-Hispanic white hypertensives belonging to hypertensive sibships...
  79. pmc Ankle brachial pressure index (ABPI): An update for practitioners
    Mo Al-Qaisi
    Imperial College, Suite 280, 28 Old Brompton Road, London SW7 3SS, UK
    Vasc Health Risk Manag 5:833-41. 2009
    ..The ankle brachial pressure index (ABPI) test is widely used by a diverse range of practitioners (in the community and ..
  80. ncbi Subintimal angioplasty for below-the-ankle arterial occlusions in diabetic patients with chronic critical limb ischemia
    Yue Qi Zhu
    Department of Radiology, The Sixth Affiliated People s Hospital, Medical School of Shanghai Jiao Tong University, Shanghai, China
    J Endovasc Ther 16:604-12. 2009
    To assess the feasibility and efficacy of subintimal angioplasty (SA) in the treatment of below-the-ankle arterial occlusion in diabetic patients with chronic critical limb ischemia (CLI).
  81. ncbi Changes in corticospinal function and ankle motor control during recovery from incomplete spinal cord injury
    Brigitte Wirth
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neurotrauma 25:467-78. 2008
    ..This study assessed changes in corticospinal tract (CST) function by measuring motor-evoked potentials (MEPs) and ankle motor control at 1, 3, and 6 months after acute iSCI...
  82. ncbi Relationship of ankle blood pressures to cardiovascular events in older adults
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, GSPH 505A Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Stroke 39:863-9. 2008
    Low values of ankle-arm systolic blood pressure ratio predict mortality and cardiovascular events. High values, associated with arterial calcification, also carry risk for mortality...
  83. ncbi Ankle valgus deformity secondary to proximal migration of the fibula in tibial lengthening with use of the Ilizarov external fixator
    Hui Wan Park
    Department of Orthopaedic Surgery, Severance Children s Hospital, Yonsei University College of Medicine, Seodaemun gu, Seoul, South Korea
    J Bone Joint Surg Am 93:294-302. 2011
    b>Ankle valgus deformity secondary to proximal migration of the fibula following an Ilizarov tibial lengthening has not been discussed in detail in the literature...
  84. ncbi Iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) fast spin-echo imaging of the ankle: initial clinical experience
    Samuel Fuller
    Department of Radiology, Grant Building S0 68B, Stanford University, 300 Pasteur Drive, Stanford, CA 94305 5105, USA
    AJR Am J Roentgenol 187:1442-7. 2006
    ..either suboptimal signal-to-noise ratio (SNR), or the inability to obtain consistent fat suppression around the ankle joint...
  85. ncbi Reorganization and enhanced functional connectivity of motor areas in repetitive ankle movements after training in locomotor attention
    Katiuscia Sacco
    CCS fMRI, Neuroradiology at Koelliker Hospital and Department of Psychology at University of Turin, Italy
    Brain Res 1297:124-34. 2009
    ..expanded activations found in the previous study were present also using an overt foot motor task consisting of ankle dorsiflexion; a control task requiring hand movements was also administered...
  86. ncbi Cardio-ankle vascular index is a candidate predictor of coronary atherosclerosis
    Keijiro Nakamura
    Department of Cardiovascular Center, Sakura Medical Center, School of Medicine, Toho University, Japan
    Circ J 72:598-604. 2008
    Recently, arterial stiffness parameter called cardio-ankle vascular index (CAVI) has been developed...
  87. ncbi The effects of external cues on ankle control during gait initiation in Parkinson's disease
    Koichi Hiraoka
    Department of Physical Therapy, Osaka Prefecture University, 3 7 30, Habikino, Habikino City, 583 8555 Osaka, Japan
    Parkinsonism Relat Disord 12:97-102. 2006
    The present study investigated the effects of external cues on motor control of the ankle joint during gait initiation in patients with Parkinson's disease (PD) and in age-matched healthy subjects...
  88. ncbi Frequency of a low ankle brachial index in the general population by age, sex and deprivation: cross-sectional survey of 28,980 men and women
    Jackie F Price
    Division of Community Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, Scotland
    Eur J Cardiovasc Prev Rehabil 15:370-5. 2008
    An increasing interest is observed in the use of the ankle brachial index (ABI, ratio of systolic blood pressure at the ankle to that in the arm) to assess cardiovascular risk...
  89. ncbi Comparison of two waist-mounted and two ankle-mounted electronic pedometers
    Murat Karabulut
    Department of Health and Exercise Science, University of Oklahoma, Norman, OK, USA
    Eur J Appl Physiol 95:335-43. 2005
    This study compared two ankle-mounted pedometers [StepWatch 3 (SW-3(Ankle)) and Activity Monitoring Pod 331 (AMP(Ankle))] and two waist-mounted pedometers [New Lifestyles NL-2000 (NL(Waist)) and Digiwalker SW-701 (SW-701(Waist))] under ..
  90. ncbi Cardio-ankle vascular index and ankle pulse wave velocity as a marker of arterial fibrosis in kidney failure treated by hemodialysis
    Atsuhiro Ichihara
    Internal Medicine, Keio University School of Medicine, Tokyo, Japan
    Am J Kidney Dis 52:947-55. 2008
    ..This study sought to compare the strength of predictions of arterial fibrosis by using a new parameter, the cardio-ankle vascular index (CAVI), versus pulse wave velocity (PWV) in patients with kidney failure treated with hemodialysis.
  91. ncbi Limitation of the resting ankle-brachial index in symptomatic patients with peripheral arterial disease
    Russell Stein
    Zena and Michael A Wiener Cardiovascular Institute, Marie Josee and Henry R Kravis Center for Cardiovascular Health, Mount Sinai Medical Center, New York, NY 10029, USA
    Vasc Med 11:29-33. 2006
    ..disease it has been recommended to screen high-risk patients for PAD in the primary care setting using the ankle-brachial index (ABI)...
  92. ncbi Prevalence of symptomatic and asymptomatic peripheral arterial disease and the value of the ankle-brachial index to stratify cardiovascular risk
    R Ramos
    Research on Inflammatory and Cardiovascular Disorders Program RICAD, Unitat de Lípids i Epidemiologia Cardiovascular ULEC, Cardiovascular, Epidemiology and Genetics Research Group EGEC, Institut Municipal d Investigacio Medica IMIM, Barcelona, Spain
    Eur J Vasc Endovasc Surg 38:305-11. 2009
    To determine the prevalence of ankle-brachial index (ABI)<0...
  93. ncbi Effects of isokinetic ankle fatigue on the maintenance of balance and postural limits
    James A Yaggie
    Department of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, USA
    Arch Phys Med Rehabil 83:224-8. 2002
    To quantify changes in balance parameters and ranges of postural control at the ankle after isokinetic fatigue.
  94. pmc Ankle: isotropic MR imaging with 3D-FSE-cube--initial experience in healthy volunteers
    Kathryn J Stevens
    Department of Radiology, Stanford University Medical Center, 300 Pasteur Dr, Room S 062A, Stanford, CA 94305, USA
    Radiology 249:1026-33. 2008
    ..3D-FSE-Cube) with a conventional two-dimensional (2D) FSE sequence for magnetic resonance (MR) imaging of the ankle. After institutional review board approval and informed consent were obtained and in accordance with HIPAA privacy ..
  95. ncbi Center effect on ankle-brachial index measurement when using the reference method (Doppler and manometer): results from a large cohort study
    Emilie Vierron
    INSERM, CIC 202, Tours, France
    Am J Hypertens 22:718-22. 2009
    The ankle-brachial index (ABI) is a simple and noninvasive tool used to detect peripheral arterial disease (PAD)...
  96. ncbi Relationship of cardio-ankle vascular index (CAVI) to carotid and coronary arteriosclerosis
    Masayasu Izuhara
    Department of Cardiovascular Medicine, Kishiwada City Hospital, Kishiwada, Japan
    Circ J 72:1762-7. 2008
    The cardio-ankle vascular index (CAVI) has been recently reported as a new index of aortic stiffness, which is less influenced by blood pressure than pulse wave velocity (PWV)...
  97. ncbi Effects of an ankle-foot orthosis on balance performance in patients with hemiparesis of different durations
    Ray Yau Wang
    Institute and Faculty of Physical Therapy, National Yang Ming University, Shih Pai, Taipei, Taiwan
    Clin Rehabil 19:37-44. 2005
    To examine the effects of an ankle-foot orthosis (AFO) on balance performance in patients with hemiparesis of short and long duration.
  98. ncbi Task-specific depression of the soleus H-reflex after cocontraction training of antagonistic ankle muscles
    Monica A Perez
    Department of Exercise and Sport Science, Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200, Copenhagen N, Denmark
    J Neurophysiol 98:3677-87. 2007
    ..have small soleus (SOL) H-reflex amplitudes, which may be related to frequent use of cocontraction of antagonistic ankle muscles...
  99. ncbi The effects of human ankle muscle vibration on posture and balance during adaptive locomotion
    K L Sorensen
    Gait and Posture Laboratory, Department of Kinesiology, University of Waterloo, Ontario N2L 3G1, Canada
    Exp Brain Res 143:24-34. 2002
    This study investigated the contribution of ankle muscle proprioception to the control of dynamic stability and lower limb kinematics during adaptive locomotion, by using mechanical vibration to alter the muscle spindle output of ..
  100. ncbi Comparison of colour duplex ultrasound and ankle-brachial pressure index measurements in peripheral vascular disease in type 2 diabetic patients with foot infections
    G Premalatha
    Madras Diabetes Research Foundation and MV Diabetes Specialities Centre P Ltd, Gopalapuram, Chennai, India
    J Assoc Physicians India 50:1240-4. 2002
    ..The aim of the study was to compare the specificity and sensitivity of ankle-brachial index (ABI) measured by peripheral doppler with the colour duplex ultrasound (CDU) for diagnosis of PVD.
  101. pmc Functional analysis of the foot and ankle myology of gibbons and bonobos
    Evie E Vereecke
    Laboratory for Functional Morphology, Department of Biology, University of Antwerp, Belgium
    J Anat 206:453-76. 2005
    This study investigates the foot and ankle myology of gibbons and bonobos, and compares it with the human foot. Gibbons and bonobos are both highly arboreal species, yet they have a different locomotor behaviour...

Research Grants81

  1. Role of NGF in inflammatory and proliferative cascades of psoriatic disease
    Siba P Raychaudhuri; Fiscal Year: 2012
    ..Psoriasis is a disease with flakey skin, and can be associated with arthritis of joints of hands, wrist, feet, ankle, knee, and spine...
  2. Effects of Evoked Resistance Training and Testosterone after Spinal Cord Injury
    Ashraf Gorgey; Fiscal Year: 2012
    ..To address this goal, surface NMES accompanied with ankle weights will be conducted twice weekly to exercise the knee extensor skeletal muscle groups from sitting position...
  3. Characterizing Ankle Function During Sloped Locomotion For Prosthesis Development
    Alena Grabowski; Fiscal Year: 2012
    ..amputation have regained normative function during level-ground walking due to the development of a new powered ankle-foot prosthesis...
  4. Sterile Hepatic Inflammation
    Wajahat Zafar Mehal; Fiscal Year: 2012
    ..This results in a very high degree of morbidity due to fatigue, jaundice, ankle swelling and pruritis...
  5. Foot Bone Motion in End Stage Ankle Arthritis Patients
    William R Ledoux; Fiscal Year: 2012
    ..The purpose of this proposal is to better understand the effects of two common treatments for end stage ankle arthritis (ESAA). Until fairly recently, the "gold standard" for treatment ESAA has been an ankle arthrodesis (i.e...
  6. Rocker Shoes for Natural Immobilization of the Ankle during Single Limb Support
    Andrew H Hansen; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Immobilization of the ankle using a walking cast or boot is a common treatment to relieve pain...
  7. Improving ambulatory community access after paralysis
    Rudi Kobetic; Fiscal Year: 2012
    ..These include individuals with weak hip and knee flexors and ankle dorsiflexors for initiating a step and weak hip flexors, ankle plantar flexor and hip extensors for generating the ..
  8. Integrated MRI-Based Examination for Evaluation of Peripheral Arterial Disease
    Felix W Wehrli; Fiscal Year: 2010
    ..The initial test for diagnosing PAD is measurement of the ankle-brachial index (ABI), a simple inexpensive test typically performed in a physician's office...
  9. BMP2 signaling of the development of osetoarthritis
    Vicki Rosen; Fiscal Year: 2013
    ..an ability to initiate fracture repair (22-24) and the progressive development of OA of the knee, elbow, wrist and ankle by 28 weeks of age (Fig 1)...
  10. Perfluoroalkyl chemicals and the risk of developing clinical and subclinical CVD
    Anoop Shankar; Fiscal Year: 2012
    ..coronary artery calcium (CAC), abdominal aortic calcium (AAC), carotid intimal-medial thickness (CIMT), low ankle-brachial index (ABI), and hypertensive left ventricular parameters including left ventricular mass, volume and ..
  11. Phase-contrast enhanced X-ray imaging system for small joints of hand
    Thomas J Beck; Fiscal Year: 2010
    ..can image with high resolution soft tissues such as cartilage and ligaments in the joints of the hand, knee and ankle. DPC has the potential to improve contrast and resolution at comparable or lower doses than used in conventional, ..
  12. Sleep and Cardiovascular Health
    Phyllis C Zee; Fiscal Year: 2012
    ..pressure, lipids, glucose, smoking, C-reactive protein), clinical and subclinical CVD (coronary artery calcium, ankle brachial index), obtained by the recently funded parent grant (R01 HL081141;Principal Investigator, Martha L...
  13. Phase-contrast X-ray imaging system for large joints
    Dan Stutman; Fiscal Year: 2012
    ..or muscle, enabling in the synchrotron experiments to image with high resolution soft tissues in the human knee, ankle or hand joints...
  14. BORRELIA BURGDORFERI MITOGEN IN DEVELOPMENT OF ARTHRITIS
    Janis J Weis; Fiscal Year: 2013
    ..post infection in the rear ankle joint. An early spike in Type I IFN, localized to joint tissue at 1 wk...
  15. Role of Femoral Atherosclerosis in Functional Status, CVD Events, and Mortality
    CHRISTINA LYNN WASSEL; Fiscal Year: 2013
    ..Even asymptomatic PAD and is associated with functional status, functional decline and loss of mobility. An ankle brachial index (ABI) <0...
  16. Effect of Prosthetic Foot-Ankle Stiffness on Amputee Function
    GLENN KLUTE; Fiscal Year: 2011
    ..ESAR) feet are to provide mechanical energy for propulsion that was once provided by the muscles crossing the ankle joint...
  17. Longtitudinal Study of Dialysis
    Rulan S Parekh; Fiscal Year: 2012
    ..valvular calcium and CT angiography as well as validated outcomes from echocardiography, pulse wave velocity and ankle brachial index...
  18. Ankle dorsiflexion splinting enhances endothelial function of aged leg muscles
    JUDY M DELP; Fiscal Year: 2013
    ..Low-load, prolonged-duration ankle dorsiflexion, which stretches the muscles of the calf, is prescribed in patients with limited range of motion and ..
  19. Paraspinal Denervation in Low Back Pain
    Andrew J Haig; Fiscal Year: 2010
    ..surgery clinic, and spine program;having them undergo examinations by a vascular and neurosurgeon as well as ankle-brachial index (ABI) testing...
  20. Boston Puerto Rican Health Study - CVD Risk Factors
    Katherine L Tucker; Fiscal Year: 2013
    ..longitudinal change in allostatic load and biochemical indicators of risk, to more concrete indicators of disease (ankle brachial index (ABI) and intima media thickness (IMT));with additional focus on social networks, neighborhood ..
  21. Retraining Spinal Circuits With Robot-Assisted Functional Electrical Stimulation
    Deborah Won; Fiscal Year: 2013
    ..Animals will be implanted with electrodes to record electrical activity from the ankle flexor and extensor muscles (EMG) and to stimulate innervating nerves...
  22. Identification of Responders to the FES Interventions in Stroke Population
    Rakesh Pilkar; Fiscal Year: 2013
    ..we will determine the 'gait symmetry'of FES assisted walking using bilateral cyclograms of the ankle and knee over a period of 6 months...
  23. PHASE-BASED CONTROL OF LOCOMOTION FOR HIGH-PERFORMANCE PROSTHESES AND ORTHOSES
    Robert D Gregg; Fiscal Year: 2013
    ..I will then implement a novel control strategy using this sense of phase on a powered knee-ankle prosthesis, which will be validated with human amputee subjects...
  24. Changing a reflex to improve locomotion
    Aiko Thompson; Fiscal Year: 2013
    ..In this population, exaggerated stretch reflex and abnormal reflex modification of the ankle extensors are frequently observed...
  25. Sex Differences in Vascular Markers of Stroke Risk
    Cheryl D Bushnell; Fiscal Year: 2012
    ..of endothelial response to ischemia), carotid-femoral pulse wave velocity (measure of arterial stiffness), and ankle-brachial index (measure of peripheral vascular disease)...
  26. Developing a brain-machine interface for an ankle robot
    Larry Forrester; Fiscal Year: 2012
    ..Baltimore VA's Maryland Exercise and Robotics Center of Excellence, we have developed an impedance controlled ankle robot (anklebot) to enhance paretic ankle motor control and gait function in stroke survivors...
  27. EMG Biofeedback with AMES
    Paul Cordo; Fiscal Year: 2010
    ..disabled stroke subjects, AMES treatment usually did not restore functional movement at the fingers, wrist, or ankle if the joint was plegic...
  28. In Vivo Imaging-Based Multiscale Modeling of Normal and Atrophied Human Lower Leg
    Shantanu Sinha; Fiscal Year: 2013
    ..Level, and (B) Multi- scale, multi-component Systems Level models will be used to predict strain distribution, ankle joint displacement and total joint force...
  29. Cortical Control of Hindlimb Muscles in Primates
    PAUL DAVID CHENEY; Fiscal Year: 2012
    ..effects on contralateral muscles, and 6) to determine the nature of output effects from M1 cortex to fast and slow ankle extensor muscles in the monkey using spike and stimulus triggered averaging of EMG activity...
  30. Sodium and Cardiovascular Disease in Patients with Chronic Kidney Disease
    Jiang He; Fiscal Year: 2010
    ..of sub-clinical CVD (coronary artery calcification score, left ventricular hypertrophy identified by Echo, and ankle-brachial index) among patients with CKD...
  31. A Virtually Supervised Web-Based Home Exercise Technology for Older Adults
    Bijan Najafi; Fiscal Year: 2013
    ..Based on the sensor signals, body segment kinematics (e.g., foot position, ankle angle, and hip angle) will be estimated in real-time using a simplified biomechanical model of the human body...
  32. MESA
    Karol Watson; Fiscal Year: 2011
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  33. MESA
    Karol Watson; Fiscal Year: 2012
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  34. MESA
    Karol Watson; Fiscal Year: 2010
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  35. MESA
    Karol Watson; Fiscal Year: 2009
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  36. The In Vivo Biomechanics of Lateral Ankle Ligament Injury and Reconstruction
    Louis E DeFrate; Fiscal Year: 2010
    Sprains of the lateral ligaments of the ankle are one of the most common injuries in sports and recreation...
  37. Foot Disorders, Pain and Physical Disability in Elders
    Marian T Hannan; Fiscal Year: 2012
    ..load in specific regions of the foot;2) these foot pressure measures and specific foot disorders, foot pain, and ankle, knee and hip joint pain;3) these foot pressure measures and lower extremity function, specifically physical ..
  38. Functional Electrical Stimulation Mediated Neuroplasticity
    Lynne R Sheffler; Fiscal Year: 2013
    ..The research focus is on footdrop, a common post-stroke impairment of ankle dorsiflexion characterized by dragging of the foot during walking, which results in an inefficient and unsafe gait ..
  39. MESA
    Russell P Tracy; Fiscal Year: 2013
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  40. MESA
    Russell P Tracy; Fiscal Year: 2011
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  41. MESA
    Aaron R Folsom; Fiscal Year: 2011
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  42. MESA
    Richard A Kronmal; Fiscal Year: 2011
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  43. MESA
    Aaron R Folsom; Fiscal Year: 2010
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  44. MESA
    Richard A Kronmal; Fiscal Year: 2013
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  45. MESA
    Richard A Kronmal; Fiscal Year: 2012
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  46. MESA
    Russell P Tracy; Fiscal Year: 2012
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  47. MESA
    Aaron R Folsom; Fiscal Year: 2013
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  48. MESA
    Russell P Tracy; Fiscal Year: 2010
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  49. MESA
    Aaron R Folsom; Fiscal Year: 2012
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  50. MESA
    Richard A Kronmal; Fiscal Year: 2010
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  51. Influence of Core Stability on Running Mechanics in Novice Runners
    AJIT MOHAN WORTHEN CHAUDHARI; Fiscal Year: 2013
    ..biomechanics will then be evaluated before and after this protocol in 25 novice runners to determine how knee and ankle loads associated with PFP and ITBS are influenced by a loss of core stability...
  52. MESA
    Richard A Kronmal; Fiscal Year: 2009
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  53. MESA
    Russell P Tracy; Fiscal Year: 2009
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  54. MESA
    Aaron R Folsom; Fiscal Year: 2009
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  55. Quantitative MRI of the Human Peripheral Nervous System In Vivo
    RICHARD DARRELL DORTCH; Fiscal Year: 2013
    ..of robust, clinically feasible, high-resolution, quantitative MRI methods (diffusion, MT, MET2) of tibial (from ankle to knee) and sciatic nerves (from knee to hip) to access the length dependent nature of certain neuropathies...
  56. Foot Progression Angle in Individuals with Diabetes &Peripheral Neuropathy
    ERICKA NAYRAM MERRIWETHER; Fiscal Year: 2013
    ..Expected outcomes: We hypothesize that foot, ankle, and hip joint motion limitations contribute substantially to excessive external FPA magnitude in adults with DMPN...
  57. PRECURSORS OF STROKE INCIDENCE AND PROGNOSIS
    Philip A Wolf; Fiscal Year: 2013
    ..carotid ultrasound, MRI and CT scans of the heart and aorta;vascular function studies - arterial stiffness, ankle-brachial index and brachial artery reactivity;and baseline and repeated quantitative brain MR scans, including ..
  58. MESA
    Steven Shea; Fiscal Year: 2010
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  59. Biomarkers of the risk for post-traumatic osteoarthritis
    James A Martin; Fiscal Year: 2010
    ..used to show that the severity of tibial plafond fractures positively correlates with the subsequent occurrence of ankle OA...
  60. MESA
    Kiang Liu; Fiscal Year: 2011
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  61. MESA
    Kiang Liu; Fiscal Year: 2013
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  62. MESA
    KIANG JOHN LIU; Fiscal Year: 2010
    ..tomography, cardiac MRI, carotid ultrasound, flow-mediated brachial artery dilation, radial artery tomometry, ankle-brachial index measurement, and retinal photography and, in subsets, abdominal aortic CT, carotid MRI, cardiac MRI ..
  63. SCI SHOULDER FUNCTION IN ASSISTIVE DEVICE GAIT
    Jacquelin Perry; Fiscal Year: 2002
    ..Motion of the shoulder, elbow, wrist, hip, knee, and ankle will be measured with the VICON Motion Analysis System...
  64. EMG Biofeedback with AMES
    Paul Cordo; Fiscal Year: 2007
    ..g., fingers, wrist, and ankle) rendered completely plegic by the stroke...
  65. Neuromuscular and positional changes after ankle joint mobilizations
    Jay N Hertel; Fiscal Year: 2010
    ..We aim to assess the acute and intermediate positional and neuromuscular changes occurring at the ankle complex after a single bout of Maitland grade 3 anteroposterior (AP) mobilizations of the distal tibiofibular and ..
  66. KINEMATICS AND STABILITY OF THE ARCH OF THE FOOT
    Harold Kitaoka; Fiscal Year: 2001
    ..Hypothesis 1: Normal gait may be observed in vitro with a dynamic ankle simulator...
  67. PROTEASE MODULATING WOUND DRESSINGS FOR THE TREATMENT OF VENOUS ULCERS
    DAVID VACHON; Fiscal Year: 2006
    ..Venous ulcers develop slowly and often initiate with swelling. These wounds typically occur above the ankle and below the knee, along the lower medial 1/3rd of the leg (medial malleolus) and result largely from venous ..
  68. IMPROVING GAIT AND FUNCTION IN CP BY STRENGTHENING THE ANKLE
    Jack Engsberg; Fiscal Year: 2009
    ..The PIs hypothesize that strengthening muscles may be an alternative to procedures that weaken muscles and that ankle strength increases can improve gait and function in persons with CP...
  69. Neuromechanical changes caused by stroke & stretching
    Li Qun Zhang; Fiscal Year: 2006
    ..The first specific aim is to treat/stretch spastic ankle joints in stroke patients safely and repeatedly to joint extreme positions until a pre-specified peak resistance ..
  70. OUTCOMES OF HEEL CORD LENGTHENING IN CHILDREN WITH CP
    Jack Engsberg; Fiscal Year: 1999
    ..When the mechanics of the angle are modeled it becomes apparent that the surgeries may not have the same effect on ankle joint function. Thus, it is possible that one surgery may be more beneficial to a specific patient than another...
  71. STABILIZING ROLE OF THE LIGAMENTS OF THE HUMAN ANKLE
    Sorin Siegler; Fiscal Year: 1990
    Traumatic injury of the ankle joint involving injury to the collateral ligaments is one of the most frequently occurring injuries at the lower limb. These injuries most frequently occur during a variety of athletic activities...
  72. Long-term Ambulatory Gait Monitor for Parkinson's Disease
    Steven Moore; Fiscal Year: 2007
    ..and gait evaluation monitor (SAGE-M) is a small device (the size of a pager) mounted on the shank just above the ankle, and consists of a combined accelerometer/gyroscope sensor array with onboard storage of data over a 24-h epoch...
  73. Neural Mechanisms Underlying Acupuncture Analgesia
    Jin Chung; Fiscal Year: 2007
    ..The present proposal describes a model of electroacupuncture (EA)- induced analgesia in ankle sprain pain...
  74. Robotic Prosthesis for Biomimetic Locomotion in Transfemoral Amputees
    Michael Goldfarb; Fiscal Year: 2010
    The overarching hypothesis of this proposal that a prosthesis with actively powered knee and ankle joints will significantly enhance the mobility of many transfemoral amputees, and therefore significantly enhance their quality of life...
  75. Race in Physician Decision to Prescribe Opioid Analgesia
    JOSHUA SARVER; Fiscal Year: 2002
    ..1) the effect of race on physicians? use of analgesics for 3 acute, painful conditions (back pain with sciatica, ankle fracture, and migraine headache); 2) whether providing information on patients? socioeconomic status, role ..
  76. PROSPECTIVE STUDY OF ANKLE INJURY RISK FACTORS
    Bruce Beynnon; Fiscal Year: 2002
    DESCRIPTION: (adapted from Investigator's abstract) Ankle ligament injuries are extremely common, accounting for up to 28% of all athletic injuries...
  77. Influence of Ankle Motion on Bilateral Amputee Gait
    Steven Gard; Fiscal Year: 2004
    We propose to investigate the effect of prosthetic ankle motion on the mechanics of bilateral lower-limb amputee gait...
  78. TYPE II COLLAGEN DENATURATION IN AGING AND OSTEOARTHRITI
    Anthony Poole; Fiscal Year: 2003
    ..aging human knee articular cartilages from autopsy and OA cartilages at arthroplasty, and those from the talus (ankle) (autopsy only). Cartilage degeneration is commonly observed in the knee and rarely in the ankle...
  79. BLOOD FACTORS AND PERIPHERAL ARTERIAL DISEASE OUTCOMES
    Mary McDermott; Fiscal Year: 2004
    ..baseline blood factor levels are associated with a) progression of lower extremity arterial ischemia (decline in ankle brachial index >= 0...
  80. FES for foot-drop in hemiparesis
    John Chae; Fiscal Year: 2009
    ..Foot-drop, or inability to dorsiflex the paretic ankle during the swing phase of gait and ankle instability during stance phase are important gait abnormalities that ..
  81. Contralaterally Controlled NMES in Chronic Ankle Dorsiflexor Paresis after Stroke
    Jayme S Knutson; Fiscal Year: 2010
    ..A major contributor to impaired ambulation is the inability to dorsiflex the ankle during the swing phase of gait, which results in inefficient and unsafe ambulation or non-ambulation...