lumbosacral region

Summary

Top Publications

  1. ncbi Disc arthroplasty design influences intervertebral kinematics and facet forces
    Marc Antoine Rousseau
    Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA 94143, USA
    Spine J 6:258-66. 2006
  2. ncbi Electrophysiologic changes in dorsal root ganglion neurons and behavioral changes in a lumbar radiculopathy model
    Takashi Kirita
    Department of Orthopaedic Surgery, School of Medicine, Sapporo Medical University, Sapporo, Japan
    Spine (Phila Pa 1976) 32:E65-72. 2007
  3. pmc Correcting abnormal flexion-relaxation in chronic lumbar pain: responsiveness to a new biofeedback training protocol
    Randy Neblett
    PRIDE Research Foundation, Dallas, TX, USA
    Clin J Pain 26:403-9. 2010
  4. ncbi Pain and motor control of the lumbopelvic region: effect and possible mechanisms
    Paul W Hodges
    Department of Physiotherapy, The University of Queensland, Brisbane, QLD 4072, Australia
    J Electromyogr Kinesiol 13:361-70. 2003
  5. ncbi Classification of sagittal thoraco-lumbo-pelvic alignment of the adolescent spine in standing and its relationship to low back pain
    Anne Smith
    School of Physiotherapy, Curtin University of Technology, Perth, Australia
    Spine (Phila Pa 1976) 33:2101-7. 2008
  6. ncbi Analysis of lumbar spine and hip motion during forward bending in subjects with and without a history of low back pain
    M A Esola
    Physical Therapy and Sport Services, Moorestown, New Jersey, USA
    Spine (Phila Pa 1976) 21:71-8. 1996
  7. ncbi Revision strategies for single- and two-level total disc arthroplasty procedures: a biomechanical perspective
    Bryan W Cunningham
    Orthopaedic Spinal Research laboratory, St Joseph Medical Center, Towson, MD 21204, USA
    Spine J 9:735-43. 2009
  8. ncbi Transfer of loads between lumbar tissues during the flexion-relaxation phenomenon
    S M McGill
    Department of Kinesiology, Faculty of Applied Health Sciences, University of Waterloo, Ontario, Canada
    Spine (Phila Pa 1976) 19:2190-6. 1994
  9. ncbi Myxopapillary ependymoma of lumbosacral region with metastasis to both cerebellopontine angles: report of a rare case
    A R Mridha
    Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
    Childs Nerv Syst 23:1209-13. 2007
  10. pmc Voluntary and reflex control of human back muscles during induced pain
    M Zedka
    Division of Neuroscience, University of Alberta, Edmonton, Canada
    J Physiol 520:591-604. 1999

Detail Information

Publications264 found, 100 shown here

  1. ncbi Disc arthroplasty design influences intervertebral kinematics and facet forces
    Marc Antoine Rousseau
    Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA 94143, USA
    Spine J 6:258-66. 2006
    ..Consequently, beneficial or adverse effects of this procedure may not be fully realized, and data for kinematic optimization are unavailable...
  2. ncbi Electrophysiologic changes in dorsal root ganglion neurons and behavioral changes in a lumbar radiculopathy model
    Takashi Kirita
    Department of Orthopaedic Surgery, School of Medicine, Sapporo Medical University, Sapporo, Japan
    Spine (Phila Pa 1976) 32:E65-72. 2007
    ..The DRG neuron was electrophysiologically investigated using a rat model with constriction of the proximal site of the DRG...
  3. pmc Correcting abnormal flexion-relaxation in chronic lumbar pain: responsiveness to a new biofeedback training protocol
    Randy Neblett
    PRIDE Research Foundation, Dallas, TX, USA
    Clin J Pain 26:403-9. 2010
    ....
  4. ncbi Pain and motor control of the lumbopelvic region: effect and possible mechanisms
    Paul W Hodges
    Department of Physiotherapy, The University of Queensland, Brisbane, QLD 4072, Australia
    J Electromyogr Kinesiol 13:361-70. 2003
    ..A new hypothesis is presented regarding the outcome from differential effects of pain on the elements of the motor system. Taken together these data argue for strategies of prevention and rehabilitation of LBP...
  5. ncbi Classification of sagittal thoraco-lumbo-pelvic alignment of the adolescent spine in standing and its relationship to low back pain
    Anne Smith
    School of Physiotherapy, Curtin University of Technology, Perth, Australia
    Spine (Phila Pa 1976) 33:2101-7. 2008
    ..A prospective study of the sagittal standing posture of 766 adolescents...
  6. ncbi Analysis of lumbar spine and hip motion during forward bending in subjects with and without a history of low back pain
    M A Esola
    Physical Therapy and Sport Services, Moorestown, New Jersey, USA
    Spine (Phila Pa 1976) 21:71-8. 1996
    ..It may be desirable to teach patients with a history of low back pain to use more hip motion during early forward bending, and hamstring stretching may be helpful for encouraging earlier hip motion...
  7. ncbi Revision strategies for single- and two-level total disc arthroplasty procedures: a biomechanical perspective
    Bryan W Cunningham
    Orthopaedic Spinal Research laboratory, St Joseph Medical Center, Towson, MD 21204, USA
    Spine J 9:735-43. 2009
    ....
  8. ncbi Transfer of loads between lumbar tissues during the flexion-relaxation phenomenon
    S M McGill
    Department of Kinesiology, Faculty of Applied Health Sciences, University of Waterloo, Ontario, Canada
    Spine (Phila Pa 1976) 19:2190-6. 1994
    ..Loading of the interspinous and supraspinous ligaments, in particular, was high relative to their failure tolerance...
  9. ncbi Myxopapillary ependymoma of lumbosacral region with metastasis to both cerebellopontine angles: report of a rare case
    A R Mridha
    Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
    Childs Nerv Syst 23:1209-13. 2007
    ..To the best of our knowledge, this is the youngest patient of metastatic myxopapillary ependymoma...
  10. pmc Voluntary and reflex control of human back muscles during induced pain
    M Zedka
    Division of Neuroscience, University of Alberta, Edmonton, Canada
    J Physiol 520:591-604. 1999
    ..A short-latency reciprocal inhibition exists between the right and left human ES. 5. It is concluded that deep back pain does not influence the stretch reflexes in the back muscles but modulates the voluntary activation of these muscles...
  11. ncbi Long-term locomotor training up-regulates TrkB(FL) receptor-like proteins, brain-derived neurotrophic factor, and neurotrophin 4 with different topographies of expression in oligodendroglia and neurons in the spinal cord
    Malgorzata Skup
    Department of Neurophysiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St 02 093 Warsaw, Poland
    Exp Neurol 176:289-307. 2002
    ..Oligodendrocytes of the spinal gray matter were particularly responsive to exercise, pointing to their involvement in activity-driven cross talk between neurons and glia...
  12. ncbi Laparoscopic repair of acquired lumbar hernia
    A Sakarya
    Celal Bayar University, Faculty of Medicine, Department of General Surgery, Manisa, Turkey
    Surg Endosc 17:1494. 2003
    ..We present two cases of laparoscopically repaired acquired lumbar hernias...
  13. ncbi MR evaluation of dural ectasia in Marfan syndrome: reassessment of the established criteria in children, adolescents, and young adults
    Christian R Habermann
    Department of Diagnostic and Interventional Radiology, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Radiology 234:535-41. 2005
    ..To retrospectively evaluate known criteria for assessment of dural ectasia by using magnetic resonance (MR) imaging in children, adolescents, and young adults with and those without Marfan syndrome...
  14. ncbi The dynamic flexion/extension properties of the lumbar spine in vitro using a novel pendulum system
    Joseph J Crisco
    Bioengineering Laboratory, Department of Orthopaedics, Brown Medical School Rhode Island Hospital, 1 Hoppin Street, CORO West, Suite 404, Providence, RI 02903, USA
    J Biomech 40:2767-73. 2007
    ..It is capable of applying physiologic compressive loads at dynamic rates without constraining the kinematics of the joints, crucial requirements for testing FSUs in vitro...
  15. ncbi Bladder and urethral pressures evoked by microstimulation of the sacral spinal cord in cats
    W M Grill
    Department of Biomedical Engineering, Applied Neural Control Laboratory, C B Bolton Building, Room 3480, Case Western Reserve University, Cleveland, OH 44106 4912, USA
    Brain Res 836:19-30. 1999
    ....
  16. ncbi Spatial segregation within the sacral parasympathetic nucleus of neurons innervating the bladder or the penis of the rat as revealed by three-dimensional reconstruction
    B Banrezes
    Analyse et Modélisation en Imagerie Biologique, I N R A Jeune Equipe 1060 77, 78352 Jouy en Josas, France
    Neuroscience 115:97-109. 2002
    ..These results support the hypothesis of a viscerotopic organization of sacral neurons providing the spinal control of pelvic organs...
  17. ncbi Response of the ligamentous lumbar spine to cyclic bending loads
    V K Goel
    Department of Biomedical Engineering, University of Iowa, Iowa City
    Spine (Phila Pa 1976) 13:294-300. 1988
    ..The presence of bending moments and axial twist along with axial compressive load may accelerate the unstable processes leading to low back pain...
  18. pmc NMDA receptors in primary afferents require phosphorylation by Src family kinases to induce substance P release in the rat spinal cord
    W Chen
    Center for Neurobiology of Stress, CURE Digestive Diseases Research Center, Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA, USA
    Neuroscience 166:924-34. 2010
    ..These results show that tyrosine-phosphorylation of these NMDA receptors is regulated by the opposite actions of Src family kinases and protein tyrosine phosphatases, and is required to induce substance P release...
  19. pmc Simulated-physiological loading conditions preserve biological and mechanical properties of caprine lumbar intervertebral discs in ex vivo culture
    Cornelis P L Paul
    Department of Orthopedic Surgery, VU University Medical Center, Amsterdam, The Netherlands
    PLoS ONE 7:e33147. 2012
    ..The characterization of caprine IVD response to culture in the LDCS under SPL conditions paves the way for controlled analysis of degeneration- and regeneration-associated processes in the future...
  20. ncbi Differential effect of glutamate receptor blockade on dendritic outgrowth in chicken lumbar motoneurons
    Xianglian Ni
    Department of Biology, University of Vermont, Burlington, VT 05405, USA
    Neuropharmacology 58:593-604. 2010
    ....
  21. ncbi Localization of L-type calcium channel Ca(V)1.3 in cat lumbar spinal cord--with emphasis on motoneurons
    Mengliang Zhang
    Department of Medical Physiology, The Panum Institute, University of Copenhagen, Blegdamsvej 3, DK 2200 Copenhagen, Denmark
    Neurosci Lett 407:42-7. 2006
    ..These results in the cat spinal cord show some differences from studies in mouse and turtle motoneurons where the immunoreactivity against this channel was mainly localized to the dendrites...
  22. ncbi Lumbar discography
    N Bogduk
    University of Newcastle Callahan, Australia
    Spine (Phila Pa 1976) 21:402-4. 1996
    ..Dr. Modic feels strongly that the test has no proven efficacy in improving patient outcomes, and feels, in fact, that it leads to inappropriate surgery...
  23. ncbi Differentiation between lumbosacral transitional vertebrae, pseudolumbarisation, and lumbosacral osteophyte formation in ventrodorsal radiographs of the canine pelvis
    S Breit
    Institute of Anatomy, University of Veterinary Medicine, Vienna, Austria
    Vet J 165:36-42. 2003
    ....
  24. ncbi Lumbosacral transitional vertebrae in dogs: classification, prevalence, and association with sacroiliac morphology
    Natascha Damur-Djuric
    Section of Neurology, Department of Small Animal Clinics, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
    Vet Radiol Ultrasound 47:32-8. 2006
    ..The resulting formative stimulus on the vertebral ossification centers, sagittally still separated, causes the various morphologies seen in LTV including the asymmetric variations...
  25. ncbi Endoscopic lumbar sympathectomy following thoracic sympathectomy in patients with palmoplantar hyperhidrosis
    Roman Rieger
    Department of Surgery, Landeskrankenhaus Gmunden, Miller von Aichholzstrasse 49, 4810, Gmunden, Austria
    World J Surg 35:49-53. 2011
    ..Especially the occurrence of unwanted side effects associated with sequential ETS and ELS has not been examined sufficiently...
  26. ncbi Structural and physiological properties of connections between individual reticulospinal axons and lumbar motoneurons of the frog
    A E Dityatev
    Department of Physiology, University of Bern, CH-3012 Bern, Switzerland
    J Comp Neurol 430:433-47. 2001
    ....
  27. ncbi The diameter of the vertebral canal in dogs in cases of lumbosacral transitional vertebrae or numerical vertebral variations
    Sabine Breit
    Muskuloskeletal Research Group, Institute of Anatomy, University of Veterinary Medicine Vienna, Veterinarplatz 1, 1210 Vienna, Austria
    Anat Embryol (Berl) 205:125-33. 2002
    ..When using S1 or the transitional vertebra as the landmark for determination of the appropriate site for subarachnoid cannulation, this site is expected to range within the same limits regardless of the vertebral formula...
  28. ncbi Surgical experience of 120 patients with lumbosacral lipomas
    H Arai
    Department of Neurosurgery, Juntendo University, Tokyo, Japan
    Acta Neurochir (Wien) 143:857-64. 2001
    ..Concerning prophylactic surgery for asymptomatic patients, the former group of patients are obviously good candidates, but the latter group is not...
  29. ncbi Uterus-like mass of müllerian origin in the lumbosacral region causing cord tethering. Report of two cases
    Mehar Chand Sharma
    Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
    J Neurosurg Spine 6:73-6. 2007
    The presence of müllerian-origin tissue in the lumbosacral region is extremely uncommon. The authors report two cases of müllerian-origin tissue in that region...
  30. ncbi Strength and fatigue of lumbar extensor muscles in older adults
    Devinder Kaur Ajit Singh
    Faculty of Health Sciences, Jalan Raja Muda Aziz, National University of Malaysia, Kuala Lumpur, Malaysia
    Muscle Nerve 44:74-9. 2011
    ..Loss of lumbar extensor muscle strength and fatigue resistance may contribute to functional disability...
  31. ncbi Transforaminal epidural steroid injections in lumbosacral radiculopathy: a prospective randomized study
    Vijay B Vad
    The Hospital for Special Surgery, New York, New York 10021, USA
    Spine (Phila Pa 1976) 27:11-6. 2002
    ..A prospective study randomized by patient choice from the private practice of a single physician affiliated with a major teaching hospital was conducted...
  32. ncbi Tuberculous osteomyelitis of the lumbosacral region: a spinal epidural abscess with presacral extension
    Orhan Buyukbebeci
    Department of Orthopaedic Surgery, School of Medicine, Gaziantep University, Turkey
    Arch Orthop Trauma Surg 124:346-8. 2004
    Tuberculous osteomyelitis in the lumbosacral region is an uncommon occurrence, and its treatment is not well-defined in the literature, particularly when it is associated with abscess formation...
  33. ncbi Dynamic adjustments of walking behavior dependent on noxious input in experimental low back pain
    R Moe-Nilssen
    Section of Physiotherapy Science, Faculty of Medicine, University of Bergen, Ulriksdal 8c, N 5009, Bergen, Norway
    Pain 83:477-85. 1999
    ..It appears that this new method is suitable for detection of continuous subconscious changes of body accelerations during walking in relation to pain...
  34. ncbi Results after surgery for lumbosacral lipoma: the significance of early and late worsening
    F van Calenbergh
    Department of Neurosurgery, University Hospital Gasthuisberg, Catholic University, Herestraat 49, B 3000 Leuven, Belgium
    Childs Nerv Syst 15:439-42; discussion 443. 1999
    ..This can be interpreted as an argument against prophylactic surgery in asymptomatic patients...
  35. ncbi Movement system impairment-based categories for low back pain: stage 1 validation
    Linda R Van Dillen
    Program in Physical Therapy, Washington University School of Medicine, St Louis, MO 63110, USA
    J Orthop Sports Phys Ther 33:126-42. 2003
    ..Cross-sectional study of patients with mechanical low back pain (MLBP)...
  36. ncbi Quantifying the lumbar flexion-relaxation phenomenon: theory, normative data, and clinical applications
    Randy Neblett
    PRIDE Research Foundation, Dallas, TX, USA
    Spine (Phila Pa 1976) 28:1435-46. 2003
    ....
  37. ncbi Altered lumbopelvic movement control but not generalized joint hypermobility is associated with increased injury in dancers. A prospective study
    Nathalie Anne Roussel
    Division of Musculoskeletal Physiotherapy, Department of Health Sciences, Artesis University College of Antwerp, Belgium
    Man Ther 14:630-5. 2009
    ..Neither generalized joint hypermobility, evaluated with the Beighton score, nor a history of LBP was predictive of injuries. Further study of these interactions is required...
  38. ncbi Preganglionic approach to transforaminal epidural steroid injections
    Henry L Lew
    Physical Medicine and Rehabilitation Service, VA Palo Alto Health Care System, Stanford University School of Medicine, Palo Alto, California, USA
    Am J Phys Med Rehabil 83:378. 2004
  39. ncbi Trunk muscle stabilization training plus general exercise versus general exercise only: randomized controlled trial of patients with recurrent low back pain
    George A Koumantakis
    School of Physical Therapy, Drosopoulou 6, Kypseli, Athens 112 57, Greece
    Phys Ther 85:209-25. 2005
    ....
  40. ncbi Deep and superficial fibers of the lumbar multifidus muscle are differentially active during voluntary arm movements
    G Lorimer Moseley
    Prince of Wales Medical Research Institute and the University of New South Wales, Sydney, Australia
    Spine (Phila Pa 1976) 27:E29-36. 2002
    ..A cross-sectional study was conducted...
  41. ncbi Activity- and target-dependent regulation of large-conductance Ca2+-activated K+ channels in developing chick lumbar motoneurons
    Miguel Martin-Caraballo
    Department of Biology and Biochemistry, University of Houston, Houston, Texas 77204 5513, USA
    J Neurosci 22:73-81. 2002
    ..Conversely, tetrodotoxin caused a decrease in K(Ca) expression in cultured E8 LMNs developing for 3 d in the presence of neurotrophic factors that promote neuronal survival in the absence of target tissues...
  42. ncbi Radiographic findings during recovery from discospondylitis
    M H Shamir
    Neurology Department, Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel
    Vet Radiol Ultrasound 42:496-503. 2001
    ..This radiographic deterioration, despite successful antibiotic therapy, appeared shorter in young dogs (less than one year old) and lasted three to nine weeks in older dogs...
  43. ncbi A randomized controlled trial comparing 2 types of spinal manipulation and minimal conservative medical care for adults 55 years and older with subacute or chronic low back pain
    Maria A Hondras
    Palmer Center for Chiropractic Research, Davenport, Iowa 52803, USA
    J Manipulative Physiol Ther 32:330-43. 2009
    ..The purpose of this study was to compare the effects of 2 biomechanically distinct forms of SM and minimal conservative medical care (MCMC) for participants at least 55 years old with subacute or chronic nonradicular LBP...
  44. ncbi Trunk muscle recruitment patterns in patients with low back pain enhance the stability of the lumbar spine
    Jaap H van Dieen
    Institute for Fundamental and Clinical Human Movement Sciences, Faculty of Human Movement Sciences, Vrije Universiteit, Amsterdam, The Netherlands
    Spine (Phila Pa 1976) 28:834-41. 2003
    ..A comparative study of trunk muscle recruitment patterns in healthy control subjects and patients with chronic low back pain was conducted...
  45. pmc Trunk control during standing reach: A dynamical system analysis of movement strategies in patients with mechanical low back pain
    Sheri P Silfies
    Drexel University, Philadelphia, PA 19102 1192, USA
    Gait Posture 29:370-6. 2009
    ....
  46. ncbi Dorsal root ganglia in the lumbosacral region observed from the axial views of MRI
    C Hamanishi
    Department of Orthopaedics, Kinki University School of Medicine, Osaka, Japan
    Spine (Phila Pa 1976) 18:1753-6. 1993
    A total number of 442 dorsal root ganglia (DRG) in the lumbosacral region of 104 patients were depicted from the axial views of MRI and their localities were classified as intraspinal, intraforaminal, or extraforaminal types...
  47. ncbi Intersegmental synchronization of spontaneous activity of dorsal horn neurons in the cat spinal cord
    E Manjarrez
    Department of Physiology, Biophysics and Neurosciences, Centro de Investigacion y Estudios Avanzados del Instituto Politecnico Nacional, Apartado Postal 14 740, Mexico, DF 07000, Mexico
    Exp Brain Res 148:401-13. 2003
    ....
  48. pmc Transforaminal epidural steroid injection for lumbosacral radiculopathy: preganglionic versus conventional approach
    Joon Woo Lee
    Department of Radiology, Seoul National University Bundang Hospital, Gyeongi do, Korea
    Korean J Radiol 7:139-44. 2006
    ....
  49. ncbi Evaluation of a physician education intervention to improve primary care for low-back pain. II. Impact on patients
    D Cherkin
    Center for Health Studies, Seattle, Washington
    Spine (Phila Pa 1976) 16:1173-8. 1991
    ..Despite its apparent benefit to physicians, the intervention did not result in significant improvements in any patient outcomes, even for the subset of patients whose physicians had perceived the greatest benefit...
  50. ncbi The effect of modifying patient-preferred spinal movement and alignment during symptom testing in patients with low back pain: a preliminary report
    Linda R Van Dillen
    Program in Physical Therapy, Washington University School of Medicine, St Louis, MO 63108 2212, USA
    Arch Phys Med Rehabil 84:313-22. 2003
    ..To examine the effect on symptoms of modifying patient-preferred movements and alignments of the lumbar spine during patient examination...
  51. pmc Immediate effects of spinal manipulation on thermal pain sensitivity: an experimental study
    Steven Z George
    Department of Physical Therapy, Brooks Center for Rehabilitation Studies, PO Box 100154, University of Florida, Gainesville, FL 32610 0154, USA
    BMC Musculoskelet Disord 7:68. 2006
    ....
  52. ncbi True intraspinal neurenteric cyst in the lumbosacral region--case report
    Masatoshi Yunoki
    Department of Neurosurgery, Kagawa Rosai Hospital, Japan
    Neurol Med Chir (Tokyo) 47:237-9. 2007
    ..Neurenteric cyst should be considered in the diagnosis of isolated cystic mass lesion at the lumbosacral region even in the absence of vertebral or visceral abnormality.
  53. ncbi The role of paraspinal muscle spindles in lumbosacral position sense in individuals with and without low back pain
    S Brumagne
    Department of Rehabilitation Sciences, Faculty of Physical Education and Physiotherapy, Katholieke Universiteit Leuven, Leuven, Belgium
    Spine (Phila Pa 1976) 25:989-94. 2000
    ..A two-group experimental design with repeated measures on one factor was used...
  54. ncbi Cystitis-induced upregulation of tyrosine kinase (TrkA, TrkB) receptor expression and phosphorylation in rat micturition pathways
    Li Ya Qiao
    Department of Neurology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Comp Neurol 454:200-11. 2002
    ....
  55. ncbi Extraforaminal entrapment of the fifth lumbar spinal nerve by osteophytes of the lumbosacral spine: anatomic study and a report of four cases
    Morio Matsumoto
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 27:E169-73. 2002
    ....
  56. ncbi Developmental characteristics of AMPA receptors in chick lumbar motoneurons
    Xianglian Ni
    Department of Biology, University of Vermont, Burlington, Vermont 05405, USA
    Dev Neurobiol 67:1419-32. 2007
    ..These findings raise the possibility that Ca2+ influx through Ca(2+)-permeable AMPA receptors plays an important role during early embryonic development in chick spinal motoneurons...
  57. ncbi Lumbar paraspinal muscle function, perception of lumbar position, and postural control in disc herniation-related back pain
    Ville Leinonen
    Department of Physical and Rehabilitation Medicine, Kuopio University Hospital, Kuopio, Finland
    Spine (Phila Pa 1976) 28:842-8. 2003
    ..A follow-up study evaluating postural control, lumbar movement perception, and paraspinal muscle reflexes in disc herniation-related chronic low back pain (LBP) before and after discectomy...
  58. ncbi Are lumbar repositioning errors larger among patients with chronic low back pain compared with asymptomatic subjects?
    Malin Asell
    Centre for Musculoskeletal Research, University of Gavle, Gavle, Sweden
    Arch Phys Med Rehabil 87:1170-6. 2006
    ..To resolve the debate over whether lumbar repositioning acuity is reduced in patients with chronic low back pain (CLBP) by using a study design and methodology to minimize the effects of potential confounders...
  59. ncbi Intact carrageenan-induced thermal hyperalgesia in mice lacking inducible nitric oxide synthase
    F Tao
    Department of Anesthesiology and Critical Care Medicine, Blalock 1415, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287 4965, USA
    Neuroscience 120:847-54. 2003
    ..This suggests that iNOS may be sufficient, but not essential, for the late phase of the carrageenan-induced thermal hyperalgesia...
  60. ncbi Trunk stiffness increases with steady-state effort
    M G Gardner-Morse
    Department of Orthopaedics and Rehabilitation, University of Vermont, Burlington, VT 05405 0084, USA
    J Biomech 34:457-63. 2001
    ..The measured increase in trunk stiffness probably results from increased muscle stiffness with increased muscle activation at higher steady-state efforts...
  61. ncbi Contemporary concepts in spine care. Epidural steroid injections
    S M Weinstein
    Puget Sound Sports and Spine Physicians, Washington, USA
    Spine (Phila Pa 1976) 20:1842-6. 1995
    ....
  62. ncbi Core strengthening
    Venu Akuthota
    Departmento fRehabilitation MEdicine, University of Colorado, Denver, USA
    Arch Phys Med Rehabil 85:S86-92. 2004
    ..The intent of this review is to describe the available literature on core strengthening using a theoretical framework...
  63. ncbi The effects of a 3-week use of lumbosacral orthoses on proprioception in the lumbar spine
    Jacek Cholewicki
    Biomechanics Research Laboratory, Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT 06520 8071, USA
    J Orthop Sports Phys Ther 36:225-31. 2006
    ..Longitudinal, repeated-measures, factorial design. The trunk axial rotation repositioning error was the dependent variable, while the orthoses, test mode (passive versus active), and the testing session were the independent variables...
  64. ncbi Different effect of locomotor exercise on the homogenate concentration of amino acids and monoamines in the rostral and caudal lumbar segments of the spinal cord in the rat
    M Skup
    Nencki Institute of Experimental Biology, Warsaw, Poland
    Spinal Cord 45:140-8. 2007
    ..The effect of long-term (4 weeks) moderate locomotor exercise on segmental distribution of glutamate (Glu), aspartate, gamma-aminobutyric acid, glycine (Gly), serotonin and noradrenaline in the spinal cord of adult rats was investigated...
  65. ncbi A novel technique of lumbar hernia repair using bone anchor fixation
    A M Carbonell
    Department of General Surgery, Carolinas Laparoscopic and Advanced Surgery Program, Carolinas Medical Center, 1000 Blythe Boulevard, Charlotte, NC 28203, USA
    Hernia 9:22-5. 2005
    ..Suture bone anchors ensure secure fixation of the mesh to the iliac crest and may eliminate a common area of recurrence...
  66. ncbi Lumbosacral orthoses reduce trunk muscle activity in a postural control task
    Jacek Cholewicki
    Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, P O Box 208071, New Haven CT 06520 8071, USA
    J Biomech 40:1731-6. 2007
    ..It was hypothesized that such a reduction in muscle co-contraction could benefit patients with low back pain, who exhibit elevated muscular activity during postural tasks such as walking, standing and sitting...
  67. ncbi Effect of wearing a lumbar orthosis on trunk muscles: study of the muscle strength after 21days of use on healthy subjects
    Isabelle Fayolle-Minon
    Service de médecine physique et réadaptation, EA 3062, Université Jean Monnet, CHU Saint Etienne, Hopital Bellevue, 42055 Saint Etienne Cedex 2, France
    Joint Bone Spine 75:58-63. 2008
    ..Randomized and controlled study of clinical evaluation of medical device in healthy subjects...
  68. ncbi Effectiveness of a lumbar belt in subacute low back pain: an open, multicentric, and randomized clinical study
    Paul Calmels
    Service de médecine physique et réadaptation, Université Jean Monnet, Hopital Bellevue, Saint Etienne, France
    Spine (Phila Pa 1976) 34:215-20. 2009
    ..Multicentric, randomized, and controlled study of clinical evaluation of medical device in subacute low back pain...
  69. ncbi Laparoscopic lumbar hernia repair
    Atul K Madan
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Am Surg 72:318-21. 2006
    ..Herein, we describe two patients with lumbar hernias (one with a recurrent traumatic hernia and one with an incisional hernia). Both of these hernias were successfully repaired laparoscopically...
  70. ncbi Estrogen receptor expression in lumbosacral dorsal root ganglion cells innervating the female rat urinary bladder
    Haley L Bennett
    Prince of Wales Medical Research Institute, University of New South Wales, NSW 2052, Sydney, Australia
    Auton Neurosci 105:90-100. 2003
    ..The coexistence of ERalpha and ERbeta suggests a broad range of potential mechanisms by which estrogens may exert their genomic effects in this system...
  71. ncbi Horizontal sacrum as an indicator of a tethered spinal cord
    R Shane Tubbs
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Pediatr Neurosurg 36:209-13. 2002
    ..We hypothesize that the LSA in this group of children is altered by a tethered spinal cord and that the horizontal nature of the sacrum may predate the clinically appreciable symptoms of a tethered spinal cord...
  72. ncbi Lumbosacral interspinous ligament rupture associated with acute intrinsic spinal muscle degeneration
    J Randy Jinkins
    Medical College of Pennsylvania Hahnemann, Drexel University, Philadelphia, Pennsylvania, USA
    JBR-BTR 86:226-30. 2003
    ..To demonstrate lumbosacral interspinous ligament rupture, with or without related paraspinal muscle degeneration...
  73. pmc Lumbar incisional hernias: diagnostic and management dilemma
    Jihad R Salameh
    University of Mississippi Medical Center, Jackson, Mississippi 39216, USA
    JSLS 8:391-4. 2004
    ..They are bounded by the 12th rib, the iliac crest, the erector spinae, and the external oblique muscle. Most postoperative incisional hernias occur in nephrectomy or aortic aneurysm repair incisions...
  74. ncbi Laparoscopic management of inferior lumbar hernia (Petit triangle hernia)
    T Ipek
    Cemil Aslan Guder Sok Yilmaz 42 Ap, D 5 Gayrettepe, Istanbul, Turkey
    Hernia 9:184-7. 2005
    ..Patients benefit from a minimally invasive approach with less pain, shortened hospital course, less analgesic requirements, better cosmetic result, and minimal life-style interference...
  75. ncbi Muscular dysfunction elicited by creep of lumbar viscoelastic tissue
    M Solomonow
    Occupational Medicine Research Center, Department of Orthopaedic Surgery, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    J Electromyogr Kinesiol 13:381-96. 2003
    ..It is suggested that a significant insight is gained as to the development and implications of a common idiopathic low back disorder as well as to the development of cumulative trauma disorders...
  76. ncbi Treatment of a case of subacute lumbar compartment syndrome using the Graston technique
    Warren I Hammer
    Cleveland Chiropractic College, National University of Health Sciences, USA
    J Manipulative Physiol Ther 28:199-204. 2005
    ..To discuss subacute lumbar compartment syndrome and its treatment using a soft tissue mobilization technique...
  77. ncbi Laparoscopic surgery for treatment of incisional lumbar hernia
    M Tobias-machado
    Section of Urology, ABC Medical School, Santo Andre, Sao Paulo, Brazil
    Int Braz J Urol 31:309-14. 2005
    ..To present results obtained with laparoscopic correction of incisional lumbar hernia in patients with minimum follow-up of 1 year...
  78. ncbi Laparoscopic tension-free hernioplasty for lumbar hernia
    K Maeda
    Department of Surgery, Nanto General Hospital, 2007 5 Umeno, Fukumitsumachi, Nishitonamigun, Toyama 939 1724, Japan
    Surg Endosc 17:1497. 2003
    ..This technique, which provides an excellent operative view, is safe, feasible, and minimally invasive. We conclude that laparoscopic tension-free repair should be the preferred option for the treatment of lumbar hernia...
  79. ncbi Changes in scoliotic curvature and lordotic angle during the early phase of degenerative lumbar scoliosis
    Yasuaki Murata
    Department of Orthopaedic Surgery, School of Medicine, Chiba University, Chiba City, Japan
    Spine (Phila Pa 1976) 27:2268-73. 2002
    ..Longitudinal radiographic measurements of the lumbar alignment in clinical cases were performed...
  80. ncbi Ambulatory laparoscopic repair of inferior lumbar or Petit hernia: a case report
    A Moreno-Egea
    Department of General Surgery, Abdominal Wall and Laparoscopy Unit, JMa Morales Meseguer Hospital, 30500 Murcia, Spain
    Surg Endosc 16:1107. 2002
    ..The laparoscopic approach enabled us to identify the whole of the lumbar area and effect a profound reconstruction on the same side as the defect...
  81. ncbi Use-dependent modulation of inhibitory capacity in the feline lumbar spinal cord
    Niranjala J K Tillakaratne
    Department of Physiological Science, University of California, Los Angeles, Los Angeles, California 90095 1761, USA
    J Neurosci 22:3130-43. 2002
    ..This modulation is specific to the motor task that is performed repetitively and is closely linked to the ability of the animal to perform a specific motor task...
  82. ncbi 1987 Volvo award in basic science. The morphology of the lumbar erector spinae
    J E Macintosh
    Department of Anatomy, University of Queensland, St Lucia, Australia
    Spine (Phila Pa 1976) 12:658-68. 1987
    ....
  83. ncbi Mechanisms of action of lumbar supports: a systematic review
    M N van Poppel
    Institute for Research in Extramural Medicine and Human Movement Sciences Vrije Universiteit, Amsterdam, The Netherlands
    Spine (Phila Pa 1976) 25:2103-13. 2000
    ..A systematic review and meta-analysis of studies on the putative mechanisms of action of lumbar supports in lifting activities...
  84. ncbi Evidence of lumbar multifidus muscle wasting ipsilateral to symptoms in patients with acute/subacute low back pain
    J A Hides
    Department of Physiotherapy, Mater Hospital, Brisbane, Australia
    Spine (Phila Pa 1976) 19:165-72. 1994
    ..The fact that reduced CSA, i.e., wasting, was unilateral and isolated to one level suggests that the mechanism of wasting was not generalized disuse atrophy or spinal reflex inhibition.(ABSTRACT TRUNCATED AT 250 WORDS)..
  85. ncbi Sensory-motor control of the lower back: implications for rehabilitation
    G R Ebenbichler
    Department of Physical Medicine and Rehabilitation, University Hospital of Vienna, Vienna, Austria
    Med Sci Sports Exerc 33:1889-98. 2001
    ..The impact of pain and muscle injury on the muscular support for the lumbar motion segment will be discussed along with the deficits in neuromuscular control in LBP patients with decreased segmental lumbar stability...
  86. pmc Muscle fibre size and type distribution in thoracic and lumbar regions of erector spinae in healthy subjects without low back pain: normal values and sex differences
    A F Mannion
    Department of Anatomy, University of Bristol, UK
    J Anat 190:505-13. 1997
    ....
  87. pmc An unusual presentation of a lumbar hernia
    A Hindmarsh
    Deptartment of Accident and Emergency, Broomfield Hospital, Chelmsford, CM1 7BU, UK
    Emerg Med J 19:460. 2002
  88. ncbi Classification by position of dorsal root ganglia in the lumbosacral region
    M Hasue
    Department of Orthopaedic Surgery, Japan Red Cross Medical Center, Tokyo
    Spine (Phila Pa 1976) 14:1261-4. 1989
    ..Although the proximally placed dorsal root ganglia may offer a locus minoris resistantiae for neural irritation and compression, its role for symptom production of radiculopathy should be further analyzed...
  89. ncbi Endoscopic extraperitoneal lumbar sympathectomy for plantar hyperhidrosis: case report
    M Y Tseng
    Division of Neurosurgery, Department of Surgery, Medical School and Hospital, National Taiwan University, 7 Chung-Shan South Road, Taipei 100, Taiwan
    J Clin Neurosci 8:555-6. 2001
    ..During the follow up period, both feet were warm and dry, although only the right side lumbar sympathectomy had been performed. The outcome appeared to be compatible with that of an open procedure but with minimal invasiveness...
  90. ncbi The use of a lumbar spine manipulation technique by physical therapists in patients who satisfy a clinical prediction rule: a case series
    Joshua A Cleland
    Department of Physical Therapy, Franklin Pierce College, Concord, NH 03301, USA
    J Orthop Sports Phys Ther 36:209-14. 2006
    ..A case series of patients with low back pain (LBP) who satisfy a clinical prediction rule (CPR)...
  91. pmc Lumbar spine stability can be augmented with an abdominal belt and/or increased intra-abdominal pressure
    J Cholewicki
    Biomechanics Laboratory, Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, P O Box 208071, New Haven, CT 06520 8071, USA
    Eur Spine J 8:388-95. 1999
    ..However, the benefits of the belt must be interpreted with caution in the context of the decreased activation of a few trunk extensor muscles...
  92. ncbi Sitting with adjustable ischial and back supports: biomechanical changes
    Mohsen Makhsous
    Sensory Motor Performance Program, Rehabilitation Institute of Chicago, Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, Illinois 60611, USA
    Spine (Phila Pa 1976) 28:1113-21; discussion 1121-2. 2003
    ....
  93. ncbi Region-specific changes in the phosphorylation of ERK1/2 and ERK5 in rat micturition pathways following cyclophosphamide-induced cystitis
    Li Ya Qiao
    Department of Physiology, Box 980551, Virginia Commonwealth University, Richmond, VA 23298 0551, USA
    Am J Physiol Regul Integr Comp Physiol 292:R1368-75. 2007
    ....
  94. ncbi Passive stiffness of the lumbar torso in flexion, extension, lateral bending, and axial rotation. Effect of belt wearing and breath holding
    S McGill
    Department of Kinesiology, University of Waterloo, Ontario, Canada
    Spine (Phila Pa 1976) 19:696-704. 1994
    ....
  95. ncbi Changes in galanin immunoreactivity in rat lumbosacral spinal cord and dorsal root ganglia after spinal cord injury
    K Zvarova
    Department of Neurology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Comp Neurol 475:590-603. 2004
    ..Changes in galanin expression in micturition pathways after SCI may be mediated by changing neurotrophic factor expression, particularly BDNF. These changes may contribute to urinary bladder dysfunction after SCI...
  96. ncbi Effect of paraspinal muscle vibration on position sense of the lumbosacral spine
    S Brumagne
    Department of Rehabilitation Sciences, Faculty of Physical Education and Physiotherapy, Katholieke Universiteit Leuven, Belgium
    Spine (Phila Pa 1976) 24:1328-31. 1999
    ..A two-group experimental design with repeated measures on one factor was used...
  97. ncbi General principles of diagnostic testing as related to painful lumbar spine disorders: a critical appraisal of current diagnostic techniques
    Joel S Saal
    SOAR, Physiatry Medical Group, Redwood City, California 94063, USA
    Spine (Phila Pa 1976) 27:2538-45; discussion 2546. 2002
    ..The literature on diagnostic tests available to the spine clinician for the evaluation of chronic low back pain was reviewed...
  98. ncbi Repositioning error in low back pain. Comparing trunk repositioning error in subjects with chronic low back pain and control subjects
    K Newcomer
    Sports Medicine Center, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA
    Spine (Phila Pa 1976) 25:245-50. 2000
    ..Further studies analyzing aspects of proprioception in subjects with low back pain are recommended...
  99. ncbi Evaluation of specific stabilizing exercise in the treatment of chronic low back pain with radiologic diagnosis of spondylolysis or spondylolisthesis
    G D Phyty
    School of Physiotherapy, Curtin University of Technology, Western Australia
    Spine (Phila Pa 1976) 22:2959-67. 1997
    ..SUMMARY: A "specific exercise" treatment approach appears more effective than other commonly prescribed conservative treatment programs in patients with chronically symptomatic spondylolysis or spondylolisthesis...
  100. ncbi Decrease in trunk muscular response to perturbation with preactivation of lumbar spinal musculature
    I A Stokes
    Departments of Orthopaedics and Rehabilitation, Physical Therapy, and Medical Biostatistics, University of Vermont, Burlington, Vermont 05405, USA
    Spine (Phila Pa 1976) 25:1957-64. 2000
    ..CONCLUSIONS: Findings are consistent with the hypothesis that the spine can be stabilized by the stiffness of activated muscles, obviating the need for active muscle responses to perturbations...
  101. ncbi Immunoreactivities of amyloid beta peptide((1-42)) and total tau protein in lumbar cerebrospinal fluid of patients with normal pressure hydrocephalus
    H Lins
    Department of Neurology, Otto von Guericke University, Magdeburg, Germany
    J Neural Transm 111:273-80. 2004
    ..92% of AD and VD samples were within the AD and non-AD area, respectively. We conclude that combined measurement of Abeta42-IR and TTIR contributes to the differential diagnosis of NPH vs. AD and of AD vs. VD, respectively...

Research Grants66

  1. A Neural Prosthesis for the Restoration of Locomotion after Spinal Cord Injury
    KEVIN ANDREW MAZUREK; Fiscal Year: 2013
    ..utilize intraspinal microstimulation (ISMS) to activate the motor neuron pools in the ventral horn of the lumbosacral region of the spinal cord where functional movements of the lower extremities can be restored...
  2. MICROSTIMULATION OF THE LUMBOSACRAL SPINAL CORD- MAPPING
    James Roppolo; Fiscal Year: 1999
    ..of neural prostheses for paraplegic individuals who have sustained injuries to their spinal cords above the lumbosacral region. In particular, evidence from current studies indicate that is possible to selectively excite neurons ..
  3. MICROSTIMULATION OF THE LUMBOSACRAL SPINAL CORD- MAPPING
    WARREN GRILL; Fiscal Year: 2000
    ..of neural prostheses for paraplegic individuals who have sustained injuries to their spinal cords above the lumbosacral region. In particular, evidence from current studies indicate that is possible to selectively excite neurons ..
  4. MICROSTIMULATION OF THE LUMBOSACRAL SPINAL CORD--CHRONI
    Douglas McCreery; Fiscal Year: 1999
    ..of neural prostheses for paraplegic individuals who have sustained injuries to their spinal cords above the lumbosacral region. In particular, it may be possible to selectively excite neurons innervating the bladder detrusor muscle ..
  5. Cross-sensitization between the bladder and colon
    HAMID AKBARALI; Fiscal Year: 2006
    ..Cell bodies in the dorsal root ganglia (DRG) of the L6-S2 lumbosacral region will be retrogradely labeled with tracer dyes injected into the colon and bladder...
  6. Neuro-Fuzzy Prediction of Spine Loads in Response to Ri*
    William Marras; Fiscal Year: 2005
    ..Second, the system will provide insights as to how the various dimensions of risk synergistically impact the musculoskeletal system. Finally, it will facilitate further investigations regarding stability and coactivity. ..
  7. BIOMECHANICAL/PSYCHOSOCIAL RISKS FOR LOW BACK DISORDERS
    William Marras; Fiscal Year: 2003
    ..We will also be able to discern when and under what conditions an intervention to improve the psycho social work environment will be likely to reduce LBP and its associated morbidity. ..
  8. MUSCLE OVEREXERTION DURING REPETITIVE LIFTING
    William Marras; Fiscal Year: 2003
    ..These results will provide quantitative guidance for the mediation of work-related LBDs for the millions of workers performing materials handling tasks in manufacturing and distribution center environments. ..
  9. AN INTEGRATED MODEL OF INTERVERTEBRAL DISC FUNCTION
    Ian Stokes; Fiscal Year: 2006
    ..and the local conditions that can influence its metabolism, eventual composition and function in three-dimensions. ..
  10. STABILITY OF MUSCULAR LOADING OF THE LUMBAR SPINE
    Ian Stokes; Fiscal Year: 2002
    ..In addition, the specific roles of individual muscles will be better elucidated, which will be helpful in guiding therapy for people with low back dysfunction. ..
  11. MECHANICAL MODULATION OF GROWTH IN PHYSES
    Ian Stokes; Fiscal Year: 2003
    ..abstract_text> ..
  12. Z Joint Changes in Low Back Pain Following Adjusting
    Gregory Cramer; Fiscal Year: 2009
    ..The results of this study will be used to increase understanding of the mechanism of action of lumbar side posture adjusting and side-posture positioning in acute LBP patients. ..
  13. Progressive scoliosis deformity in intervertebral disc
    Ian Stokes; Fiscal Year: 2009
    ..These approaches may include improvements in brace design, new possibilities for muscle rehabilitation, and surgical procedures aimed at early, minimally invasive modification of spinal growth. ..
  14. SENSORY NEURON ADDITION IN RAT
    PAUL FAREL; Fiscal Year: 2002
    ..We will also determine whether the presumed population of type-L neurons differs from nature sensory neurons in the functional differentiation. ..
  15. Preventing pressure ulcers using a new sitting concept
    Mohsen Makhsous; Fiscal Year: 2004
    ..Furthermore, we will perform extensive testing to optimize user function, while maximizing safety ..
  16. BRAIN AND SPINAL CORD CONTRIBUTIONS TO ANESTHETIC ACTION
    JOSEPH ANTOGNINI; Fiscal Year: 2005
    ..This information will aid the development of newer and safer anesthetics, as well as lead to clinically useful means of modulating the neurotransmitter systems that are themselves modulated by anesthetics. ..
  17. Female Reproductive Organs and Their Innervation.
    RAYMOND PAPKA; Fiscal Year: 2006
    ..Finally, knowledge of estrogen responsive sensory neurons has important implications for understanding neuropathic pain syndromes influenced by estrogen levels. ..
  18. Reducing Low-back Disorders Using a New Sitting Design
    Mohsen Makhsous; Fiscal Year: 2003
    ..abstract_text> ..
  19. ANESTHETIC EFFECTS ON SENSORIMOTOR INTEGRATION
    JOSEPH ANTOGNINI; Fiscal Year: 2009
    ..Understanding how and where anesthetics act will eventually lead to the development of better and safer anesthetics, thereby decreasing peri-operative morbidity and mortality and improving public health. ..
  20. Proteomic Markers for ALS
    Jonathan Glass; Fiscal Year: 2008
    ..These candidate biomarkers will be tested for their sensitivity and specificity for disease in plasma and spinal fluid samples from mice and people with ALS. [unreadable] [unreadable] [unreadable]..
  21. Mechanics of non-contact ACL injuries in female athletes
    Christopher Powers; Fiscal Year: 2007
    ..abstract_text> ..
  22. PREVENTING CO-MORBID MENTAL & PHYSICAL HEALTH DISABILITY
    Robert Gatchel; Fiscal Year: 2007
    ..These results will have implications for potentially significant healthcare cost savings for this highly prevalent co-morbid disability problem. [unreadable] [unreadable]..
  23. Axonal Protection for Multiple Sclerosis
    Jonathan Glass; Fiscal Year: 2007
    ..Combined with immunomodulatory therapy, axonal protection by calpain inhibition may significantly change the course of disease for people with MS. [unreadable] [unreadable]..
  24. MOLECULAR MECHANISMS OF HEXACARBON-INDUCED AXON ATROPHY
    RICHARD LOPACHIN; Fiscal Year: 2009
    ..Understanding the role and mechanism of axon atrophy in solvent neurotoxicity has broad-based implications for human occupational health and risk assessment. ..
  25. Enhancing Neuroprosthesis Performance with Nerve Cuff Electrodes
    Ronald J Triolo; Fiscal Year: 2010
    ....
  26. Mechanisms of Neural Mobilization for Chronic Pain
    STEVEN GEORGE; Fiscal Year: 2007
    ..These data may also provide support for a future clinical trial investigating the efficacy of median nerve NMT for patients with CTS. [unreadable] [unreadable] [unreadable]..
  27. The role of the androgen receptor in behavior
    DAMIAN ZULOAGA; Fiscal Year: 2008
    ..Experiment 3 will test whether differences in sensorimotor gating and anxiety in adulthood are the result of androgen induced organization during development. ..
  28. ELASTIC/PLASTIC HUMAN JOINT COMPLIANCE
    SERGE ROY; Fiscal Year: 2004
    ..The fourth task examines the postural aspects of the central commands and the relatively little studied aspects of how the CNS controls the transition from movement to posture. ..
  29. ROLE OF BIOMECHANICS/NEURAL PLASTICITY IN RADICULAR PAIN
    Beth Winkelstein; Fiscal Year: 2002
    ..age analysis will be used to determine the local strain tensor for particular tissue components. Tissue bins will be correlated with mechanical allodynia and neuroimmune mediators of persistent pain. ..
  30. Transducible Molecular Probes for Imaging Tumors
    Claude Sirlin; Fiscal Year: 2004
    ..abstract_text> ..
  31. BLADDER OUTLET OBSTRUCTION INDUCED NEUROPLASTICITY
    Peter Zvara; Fiscal Year: 2003
    ..lumbosacral spinal cord. Changes in connectivity between the various spinal elements will be assessed following BOO. ..
  32. 3-D DYNAMIC MOTION SEGMENT BEHAVIOR
    Martin Krag; Fiscal Year: 2004
    ....
  33. Repair of Bladder Function after Cauda Equina Injury
    Leif A Havton; Fiscal Year: 2010
    ..We believe that our proposal has translational research potential for the development of new treatments for patients with conus medullaris/cauda equina injuries. ..
  34. Paraspinal Denervation in Low Back Pain
    Andrew J Haig; Fiscal Year: 2010
    ..The results will help doctors avoid unnecessary surgery and help scientists to understand more about how spinal stenosis disables so many older people. ..
  35. Muscle Strength and Age Effects in Balance Recovery
    Michael Madigan; Fiscal Year: 2005
    ..This information can be used to develop specific intervention strategies, such as weight training regiments, aimed at fall prevention. ..
  36. DNA-crosslinked gels: New advanced biomaterials
    NOSHIR LANGRANA; Fiscal Year: 2006
    ..Moreover, the biomaterial will also be functionalized with bioactive matrix molecules to support cell attachment, growth, and migration. ..
  37. The Mechanism and Function of Lumbosacral Orthoses
    Jacek Cholewicki; Fiscal Year: 2006
    ..In addition, data generated from the proposed research will also carry-over into advancing our understanding of the mechanisms and function of ergonomic lumbar supports. ..
  38. MECHANISMS OF SEXUAL DIFFERENTIATION IN NEURAL SYSTEMS
    NANCY FORGER; Fiscal Year: 2004
    ....
  39. North American Congress on Biomechanics (NOCOB) 2008
    Richard Hughes; Fiscal Year: 2008
    ..The next NACOB meeting will be held in Ann Arbor, MI, on August 5-9, 2008. This application requests funds to reduce student registration fees. [unreadable] [unreadable] [unreadable]..
  40. MR Imaging of Non-Alcoholic Fatty Liver Disease
    Claude B Sirlin; Fiscal Year: 2010
    ..Developing a safe and accurate method to diagnose and follow this disease may lead to earlier diagnosis and more effective treatment. ..
  41. Mechanisms of specific trunk Exercises in low back pain
    Sharon M Henry; Fiscal Year: 2010
    ..This series of experiments will, for the first time, compare two classification systems used in LBP treatment and determine if they are superior to STC exercises. 4 ..
  42. Arrays for deep brain microstimulation and recording
    DOUGLAS BUCHANAN MCCREERY; Fiscal Year: 2010
    ..This technology will improve quality of life for persons afflicted with Parkinson's Disease and other movement disorders. ..
  43. Comorbidity of Mental Disorders and Pain
    Robert Gatchel; Fiscal Year: 2008
    ..This Award will enable me to maintain the momentum and clinical research advances of two previous consecutive K02 awards from NIMH. ..
  44. Novel CRF antagonists for inflammation and pain
    MARK LINDNER; Fiscal Year: 2002
    ..Orally active forms of a small molecule CRF receptor would provide a novel therapeutic strategy for indications of acute and chronic inflammation and inflamatory pain. ..
  45. EARLY DETECTION AND PREVENTION OF CHRONIC PAIN DISABILIT
    Robert Gatchel; Fiscal Year: 2003
    ..These 3 research projects will explore the efficacy of early identification of "high risk" acute patients in order to provide biobehavioral treatment intervention, while simultaneously evaluating cost-effectiveness. ..
  46. Role of Spinal GABA Receptors in Neuropathic Pain
    Donna Hammond; Fiscal Year: 2006
    ..abstract_text> ..
  47. Behavioral Interventions for Low Back Pain
    STEVEN GEORGE; Fiscal Year: 2007
    ....
  48. 3-D Multi-Articular Models of the Carpus
    Joseph Crisco; Fiscal Year: 2009
    ..These discoveries will lead to new treatments for wrist disease and trauma, which affect men and women of all ages, and account for significant medical expenses and lost productivity each year. ..
  49. Motor Control Deficit in Low Back Pain: Cause or Effect?
    Jacek Cholewicki; Fiscal Year: 2003
    ..The results of the proposed research will have a significant clinical relevance for designing more effective prevention, diagnosis, and rehabilitation strategies for LBP. ..
  50. Carpal Kinematics During Functional Tasks
    Joseph Crisco; Fiscal Year: 2008
    ..Understanding how the carpus and distal forearm function is crucial to reducing work-related upper extremity musculoskeletal disorders. ..
  51. Role of Intraspinal Plasticity in Autonomic Dysreflexia
    Alexander Rabchevsky; Fiscal Year: 2008
    ..This information will form the basis for developing potential treatments for this common and debilitating complication of SCI. ..
  52. IMPLANTED NEUROPROSTHESIS FOR STANDING AFTER SCI
    Ronald Triolo; Fiscal Year: 2006
    ..Abstract Not Provided ..
  53. PTP identity and inhibition for nigrostriatal protection
    Theo Hagg; Fiscal Year: 2003
    ..These studies will increase our understanding of how dopaminergic neurons function, validate our new treatment approach and provide us with research tools to improve it for application to Parkinson's disease. ..
  54. LOW BACK PAIN: A MOTOR CONTROL IMPAIRMENT?
    Sharon Henry; Fiscal Year: 2002
    ..By having a better understanding of trunk motor coordination, evaluation and treatment strategies can be more specific and more effective in the rehabilitation of persons with LBP. ..
  55. NEUROTROPHIN CONTROL OF REM SLEEP
    Jack Yamuy; Fiscal Year: 2004
    ..This concerted set of experiments will be critical in elucidating the role that neurotrophins play in the control of REM sleep. ..
  56. Soft Tissue Biomechanical Behavior During Acupuncture in Low Back Pain
    Helene M Langevin; Fiscal Year: 2010
    ....
  57. BIOMECHANICAL EFFECT OF ACUPUNCTURE NEEDLING
    HELENE LANGEVIN; Fiscal Year: 2001
    ..This will contribute to the fundamental understanding of acupuncture therapy and may lead to improvements in treatments. ..
  58. CONTROL OF SPINAL LOCOMOTOR ACTIVITY BY MONOAMINES
    BRIAN NOGA; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  59. Phase II Clinical Trial Assessing Efficacy and Safety of Oral Steroids vs. Vincri
    Beth Drolet; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  60. Trigeminal Mechanisms of Oral Irritation
    Earl Carstens; Fiscal Year: 2009
    ..In a corresponding animal study, we will determine if responses of neurons in the n. tractus solitarius (NTS), a taste relay, are reduced by intraoral capsaicin ..
  61. 4th International Workshop for the Study of Itch
    Earl Carstens; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..