research subjects

Summary

Summary: Persons who are enrolled in research studies or who are otherwise the subjects of research.

Top Publications

  1. pmc Reasons for participating in randomised controlled trials: conditional altruism and considerations for self
    Sharon K McCann
    Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    Trials 11:31. 2010
  2. ncbi Reactivity of measurement in health psychology: how much of a problem is it? What can be done about it?
    David P French
    Applied Research Centre in Health and Lifestyle Interventions, Faculty of Health and Life Sciences, Coventry University, UK
    Br J Health Psychol 15:453-68. 2010
  3. pmc Ethical issues posed by cluster randomized trials in health research
    Charles Weijer
    Rotman Institute of Philosophy, Department of Philosophy, University of Western Ontario, London, ON, N6A 5B8, Canada
    Trials 12:100. 2011
  4. pmc Impact of social stigma on the process of obtaining informed consent for genetic research on podoconiosis: a qualitative study
    Fasil Tekola
    School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia
    BMC Med Ethics 10:13. 2009
  5. ncbi Feedback of individual genetic results to research participants: in favor of a qualified disclosure policy
    Annelien L Bredenoord
    Department of Medical Ethics, University Medical Center Utrecht, Division Julius Center, Utrecht, The Netherlands
    Hum Mutat 32:861-7. 2011
  6. ncbi The role familiarity with science and medicine plays in parents' decision making about enrolling a child in vaccine research
    Tracey E A Chantler
    University of Oxford, United Kingdom
    Qual Health Res 17:311-22. 2007
  7. ncbi Patients or research subjects? A qualitative study of participation in a randomised controlled trial of a complex intervention
    Ben Heaven
    Health Technologies and Human Relations Research Group, Centre for Health Services Research, School of Population and Health Sciences, University of Newcastle upon Tyne, 21 Claremont Place, Newcastle upon Tyne, NE2 4AA, UK
    Patient Educ Couns 62:260-70. 2006
  8. ncbi Undue inducement in clinical research in developing countries: is it a worry?
    Ezekiel J Emanuel
    Department of Clinical Bioethics, Warren G Magnuson Clinical Center, National Institutes of Health, Building 10 Room 1C118, Bethesda, MD 20892 1156, USA
    Lancet 366:336-40. 2005
  9. ncbi HIV vaccine trials: critical issues in informed consent
    G Lindegger
    School of Psychology, University of Natal, Private Bag X01, Scottsville, Pietermaritzburg, 3209 South Africa
    S Afr J Sci 96:313-7. 2000
  10. ncbi Replicating Milgram: Would people still obey today?
    Jerry M Burger
    Deparment of Psychology, Santa Clara University, CA 95053 0001, USA
    Am Psychol 64:1-11. 2009

Detail Information

Publications258 found, 100 shown here

  1. pmc Reasons for participating in randomised controlled trials: conditional altruism and considerations for self
    Sharon K McCann
    Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    Trials 11:31. 2010
    ..The idea that altruistic-type motives are important for trial participation is understandably widespread, but recent studies suggest considerations of personal benefit can influence participation decisions in various ways...
  2. ncbi Reactivity of measurement in health psychology: how much of a problem is it? What can be done about it?
    David P French
    Applied Research Centre in Health and Lifestyle Interventions, Faculty of Health and Life Sciences, Coventry University, UK
    Br J Health Psychol 15:453-68. 2010
    ..Other aims are to describe how this may affect conclusions drawn in health psychology research and to outline where more research is needed...
  3. pmc Ethical issues posed by cluster randomized trials in health research
    Charles Weijer
    Rotman Institute of Philosophy, Department of Philosophy, University of Western Ontario, London, ON, N6A 5B8, Canada
    Trials 12:100. 2011
    ..Our hope is that these papers will serve as the basis for the creation of international ethical guidelines for the design and conduct of cluster randomized trials...
  4. pmc Impact of social stigma on the process of obtaining informed consent for genetic research on podoconiosis: a qualitative study
    Fasil Tekola
    School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia
    BMC Med Ethics 10:13. 2009
    ..The aim of this study was to explore the impact of social stigma on the process of obtaining consent for a study on the genetics of podoconiosis in Southern Ethiopia...
  5. ncbi Feedback of individual genetic results to research participants: in favor of a qualified disclosure policy
    Annelien L Bredenoord
    Department of Medical Ethics, University Medical Center Utrecht, Division Julius Center, Utrecht, The Netherlands
    Hum Mutat 32:861-7. 2011
    ..We appeal to the genetics community to make a joint effort to further refine the packages and set thresholds for result selection...
  6. ncbi The role familiarity with science and medicine plays in parents' decision making about enrolling a child in vaccine research
    Tracey E A Chantler
    University of Oxford, United Kingdom
    Qual Health Res 17:311-22. 2007
    ..It is vital to ensure that parents are confident in their judgment of a study and its potential benefit to their child and society...
  7. ncbi Patients or research subjects? A qualitative study of participation in a randomised controlled trial of a complex intervention
    Ben Heaven
    Health Technologies and Human Relations Research Group, Centre for Health Services Research, School of Population and Health Sciences, University of Newcastle upon Tyne, 21 Claremont Place, Newcastle upon Tyne, NE2 4AA, UK
    Patient Educ Couns 62:260-70. 2006
    ..To explore participants' understandings regarding treatment decisions, made within an efficacy randomised controlled trial (RCT) of decision-support tools...
  8. ncbi Undue inducement in clinical research in developing countries: is it a worry?
    Ezekiel J Emanuel
    Department of Clinical Bioethics, Warren G Magnuson Clinical Center, National Institutes of Health, Building 10 Room 1C118, Bethesda, MD 20892 1156, USA
    Lancet 366:336-40. 2005
  9. ncbi HIV vaccine trials: critical issues in informed consent
    G Lindegger
    School of Psychology, University of Natal, Private Bag X01, Scottsville, Pietermaritzburg, 3209 South Africa
    S Afr J Sci 96:313-7. 2000
    ..The transmission of information is examined as a particular aspect of IC in HIV vaccine trials...
  10. ncbi Replicating Milgram: Would people still obey today?
    Jerry M Burger
    Deparment of Psychology, Santa Clara University, CA 95053 0001, USA
    Am Psychol 64:1-11. 2009
    ..Men and women did not differ in their rates of obedience, but there was some evidence that individual differences in empathic concern and desire for control affected participants' responses...
  11. pmc Systematic review of the Hawthorne effect: new concepts are needed to study research participation effects
    Jim McCambridge
    Department of Social and Environmental Health, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, 15 17 Tavistock Place, London WC1H 9SH, UK Electronic address
    J Clin Epidemiol 67:267-77. 2014
    ..This study aims to (1) elucidate whether the Hawthorne effect exists, (2) explore under what conditions, and (3) estimate the size of any such effect...
  12. pmc Exploring concordance and discordance for return of incidental findings from clinical sequencing
    Robert C Green
    Division of Genetics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Genet Med 14:405-10. 2012
    ..The aim of this study was to explore specific conditions and types of genetic variants that specialists in genetics recommend should be returned as incidental findings in clinical sequencing...
  13. ncbi Subjects matter: a survey of public opinions about a large genetic cohort study
    David Kaufman
    Genetics and Public Policy Center, Johns Hopkins University, Washington, DC 20036, USA
    Genet Med 10:831-9. 2008
    ..To this end, 4659 Americans were surveyed about support for and willingness to participate in a proposed large cohort study...
  14. ncbi Participating in research: exploring participation and engagement in a study of self-management for people with chronic obstructive pulmonary disease
    Karen F Willis
    School of Sociology and Social Work, University of Tasmania, Launceston, Australia
    Qual Health Res 21:1273-82. 2011
    ..We argue that motivation based on dominant voluntaristic or altruistic values can be problematic for researchers attempting to demonstrate the benefits of CDSM strategies...
  15. pmc Ethical issues in human genomics research in developing countries
    Jantina de Vries
    The Ethox Centre, Department of Public Health and Primary Care, University of Oxford, Old Road Campus, Headington, Oxford, OX3 7LF, UK
    BMC Med Ethics 12:5. 2011
    ..In this paper, we draw upon the experiences of the MalariaGEN Consortium to identify specific ethical issues raised by such research in Africa, Asia and Oceania...
  16. pmc Participating in a trial in a critical situation: a qualitative study in pregnancy
    S Kenyon
    Reproductive Sciences Section, Department of Cancer Studies and Molecular Medicine, University of Leicester, UK
    Qual Saf Health Care 15:98-101. 2006
    ..Randomised controlled trials of interventions in critical situations are necessary to establish safety and evaluate outcomes. Pregnant women have been identified as a potentially vulnerable population...
  17. pmc Who is the research subject in cluster randomized trials in health research?
    Andrew D McRae
    Department of Epidemiology and Biostatistics, University of Western Ontario, London, Canada
    Trials 12:183. 2011
    ..posed, namely, who is the research subject in a CRT in health research? The identification of human research subjects is logically prior to the application of protections as set out in research ethics and regulation...
  18. ncbi Broadening consent--and diluting ethics?
    B Hofmann
    Faculty of Health Care and Nursing, University College of Gjøvik, Blindern, Gjøvik, Norway
    J Med Ethics 35:125-9. 2009
    ..This does not mean that biobank research should be abandoned or that people cannot authorise future research on donated biological material...
  19. pmc Informed consent for MRI and fMRI research: analysis of a sample of Canadian consent documents
    Nicole Palmour
    Neuroethics Research Unit, Institut de Recherches Cliniques de Montreal, Canada
    BMC Med Ethics 12:1. 2011
    ..g., informed consent forms, ethics review) are vested with extremely important ethical and practical goals. Accordingly, these measures need to function effectively in real-world research and to follow high level standards...
  20. ncbi Participant distress in psychiatric research: a systematic review
    Anthony F Jorm
    ORYGEN Research Centre, Department of Psychiatry, University of Melbourne, Victoria, Australia
    Psychol Med 37:917-26. 2007
    ..There has been ethical concern that participants in psychiatric research will become distressed and their mental state might worsen...
  21. ncbi Cross-cultural perspectives on research participation and informed consent
    Paula C Barata
    Women s Health Program, University Health Network, Toronto, Ont, Canada
    Soc Sci Med 62:479-90. 2006
    ..The Caribbean participants qualified their participation in research studies and repeatedly raised images of invasive research...
  22. ncbi Deception in psychology: moral costs and benefits of unsought self-knowledge
    Lisa Bortolotti
    Philosophy Department, University of Birmingham, Birmingham, B15 2TT, UK
    Account Res 13:259-75. 2006
    ..The community gains collective self-knowledge that, once shared, can play a role in shaping education, informing policies and in general creating a more efficient and just society...
  23. ncbi Therapeutic misconception in clinical research: frequency and risk factors
    Paul S Appelbaum
    Department of Psychiatry, University of Massachusetts Medical School, USA
    IRB 26:1-8. 2004
  24. ncbi Module three: vulnerable/special participant populations
    Jason P Lott
    University of Pennsylvania, School of Medicine 295 John Morgan Building 3620 Hamilton Walk, Philadelphia, PA 19104 6055 USA
    Dev World Bioeth 5:30-54. 2005
    ....
  25. ncbi An assessment of the Hawthorne Effect in practice-based research
    Douglas H Fernald
    Department of Family Medicine, University of Colorado Denver, Aurora, Colorado, USA
    J Am Board Fam Med 25:83-6. 2012
    ....
  26. ncbi The quality of informed consent in a clinical research study in Thailand
    Christine Pace
    Department of Clinical Bioethics, Warren G Magnuson Clinical Center, National Institutes of Health, Bethesda, MD, USA
    IRB 27:9-17. 2005
  27. ncbi International normative perspectives on the return of individual research results and incidental findings in genomic biobanks
    Ma n H Zawati
    Faculty of Medicine, Human Genetics Department, McGill University, Montreal, Quebec, Canada
    Genet Med 14:484-9. 2012
    ..This article suggests some elements to consider in order to complement available guidance at the international level...
  28. ncbi Split views among parents regarding children's right to decide about participation in research: a questionnaire survey
    U Swartling
    Division of Paediatrics, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, SE 581 85 Linkoping, Sweden
    J Med Ethics 35:450-5. 2009
    ..When asked what interests they consider most important in paediatric research, child autonomy and decision-making was ranked lowest. We discuss the implications of these findings...
  29. ncbi Participation in research and access to experimental treatments by HIV-infected patients
    Allen L Gifford
    Center for Research in Patient Oriented Care and the Quality Enhancement Research Initiative in HIV, Veterans Affairs San Diego Healthcare System, and the University of California, San Diego, California 92161, USA
    N Engl J Med 346:1373-82. 2002
    ..Although there is concern that minority groups and women are underrepresented in research involving patients with human immunodeficiency virus (HIV) infection, the available data are inconclusive...
  30. ncbi Bad news about bad news: the disclosure of risks to insurability in research consent processes
    Victoria Smith Apold
    Faculties of Law and Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    Account Res 18:31-44. 2011
    ..In this article, we seek to explain the insurability risks associated with incidental findings and to make recommendations for how researchers and research ethics committees should address the issue of disclosure of these risks...
  31. ncbi Research on stored biological samples: the views of Ugandans
    David Wendler
    Unit on Vulnerable Populations, Department of Clinical Bioethics, Warren G Magnuson Clinical Center, National Institutes of Health, Bethesda, MD, USA
    IRB 27:1-5. 2005
  32. ncbi Parental attitudes towards and perceptions of their children's participation in clinical research: a developing-country perspective
    Mona Nabulsi
    Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, Lebanon
    J Med Ethics 37:420-3. 2011
    ..In developing countries, there is a knowledge gap regarding parental perceptions of and attitudes towards their children's participation in clinical trials...
  33. ncbi The return of individual research findings in paediatric genetic research
    Kristien Hens
    Katholieke Universiteit Leuven, Centre for Biomedical Ethics and Law, Kapucijnenvoer 35 3 Box 7001, 3000 Leuven, Belgium
    J Med Ethics 37:179-83. 2011
    ..question of whether researchers have a more stringent duty to return important health information when their research subjects are children is more difficult to answer...
  34. pmc The disclosure of diagnosis codes can breach research participants' privacy
    Grigorios Loukides
    Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, Tennessee 37203, USA
    J Am Med Inform Assoc 17:322-7. 2010
    ....
  35. ncbi Reuse of samples: ethical issues encountered by two institutional ethics review committees in Kenya
    Simon K Langat
    P O Box 30568, 00100 Nairobi, Kenya
    Bioethics 19:537-49. 2005
    ..It is proposed that these issues should be addressed through policy interventions at both the national and global levels...
  36. pmc Increasing recruitment to randomised trials: a review of randomised controlled trials
    Judith M Watson
    York Trials Unit, Department of Health Sciences, University of York, York, YO10 5DD, UK
    BMC Med Res Methodol 6:34. 2006
    ..With poor recruitment being such an important issue with respect to the conduct of randomised trials, a systematic review of controlled trials on recruitment methods was undertaken in order to identify strategies that are effective...
  37. ncbi Beyond "misunderstanding": written information and decisions about taking part in a genetic epidemiology study
    Mary Dixon-Woods
    University of Leicester, Leicester, UK
    Soc Sci Med 65:2212-22. 2007
    ..These questions need to be addressed through engagement and dialogue between the research, research participants, social science, and ethics communities...
  38. ncbi Undesirable implications of disclosing individual genetic results to research participants
    Leslie A Meltzer
    Georgetown University Law Center, USA
    Am J Bioeth 6:28-30; author reply W10-2. 2006
  39. ncbi Therapeutic misconception and the appreciation of risks in clinical trials
    Charles W Lidz
    Department of Psychiatry, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
    Soc Sci Med 58:1689-97. 2004
    Studies repeatedly have shown that clinical research subjects have trouble appreciating the implications for their clinical care of participating in a clinical trial...
  40. ncbi Impact of detailed informed consent on research subjects' participation: a prospective, randomized trial
    Catherine A Marco
    Department of Emergency Medicine, St Vincent Mercy Medical Center, Toledo, Ohio 43608 2691, USA
    J Emerg Med 34:269-75. 2008
    This study was undertaken to measure potential research subjects' participation in a survey research design, based on level and type of informed consent required before enrollment...
  41. pmc Taking tissue seriously means taking communities seriously
    Ross E G Upshur
    University of Toronto Joint Centre for Bioethics, 88 College Street, Toronto, Ontario, M5G 1L4, Canada
    BMC Med Ethics 8:11. 2007
    ..This often leads to the export of human tissue (defined broadly) from the developing to the developed world for analysis. These practices raise a number of important ethical issues that require attention...
  42. ncbi Lay conceptions of the ethical and scientific justifications for random allocation in clinical trials
    Elizabeth J Robinson
    Department of Psychology, Keele University, Keele, Staffs ST5 5BG, UK
    Soc Sci Med 58:811-24. 2004
    ....
  43. ncbi A plea for pragmatism in clinical research ethics
    David H Brendel
    Harvard Medical School, McLean Hospital, Belmont, MA 02478, USA
    Am J Bioeth 8:24-31. 2008
    ....
  44. pmc Payment of clinical research subjects
    Christine Grady
    Department of Clinical Bioethics, Clinical Center, NIH, Bethesda, MD, USA
    J Clin Invest 115:1681-7. 2005
    Offering payment to clinical research subjects, in an effort to enhance recruitment by providing an incentive to take part or enabling subjects to participate without financial sacrifice, is a common yet uneven and contentious practice ..
  45. ncbi Racial differences in public perceptions of voluntariness of medical research participants in South Africa
    Nicola Wendy Barsdorf
    HIV AIDS Vaccines Ethics Group HAVEG School of Psychology, University of KwaZulu Natal, Pietermaritzburg, South Africa
    Soc Sci Med 60:1087-98. 2005
    ..Perceptions of voluntariness did not however appear to impact on participants' personal willingness to participate in future research. Implications for recruitment of future health research participants in South Africa are discussed...
  46. ncbi Utility of an automated notification system for recruitment of research subjects
    Eden Cardozo
    School of Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA
    Emerg Med J 27:786-7. 2010
    Experience with a novel method of notifying investigators about research subjects in a university-based emergency department (ED) is reported.
  47. ncbi Conducting ethical research in pediatrics: a brief historical overview and review of pediatric regulations
    Douglas S Diekema
    University of Washington, Treuman Katz Center for Pediatric Bioethics, Children s Hospital and Regional Medical Center, Seattle, Washington 98101, USA
    J Pediatr 149:S3-11. 2006
    ..Good research is ethical research, and that requires investigators who take seriously the importance of participant welfare, meaningful informed consent, and respect for research participants...
  48. ncbi Assessing benefits in clinical research: why diversity in benefit assessment can be risky
    Larry R Churchill
    Vanderbilt University, USA
    IRB 25:1-8. 2003
  49. pmc Testing vaccines in pediatric research subjects
    Robert M Jacobson
    Mayo Clinic Vaccine Research Group, Mayo Clinic, Rochester, MN, United States
    Vaccine 27:3291-4. 2009
    ..Better understanding of the restrictions in pediatric research, the use of placebos, the attitude of parents, and the concerns with remuneration can better equip the vaccine researcher in pursuing successful studies in children...
  50. ncbi Engaging with children in research: Theoretical and practical implications of negotiating informed consent/assent
    Veronica Lambert
    School of Nursing, Dublin City University, Ireland
    Nurs Ethics 18:781-801. 2011
    ....
  51. pmc Subjects agree to participate in environmental health studies without fully comprehending the associated risk
    Robin Lee
    Division of Health Studies, US Agency for Toxic Substances and Disease Registry, 4770 Buford Highway NE, MS f 57, Atlanta, GA 30341, USA
    Int J Environ Res Public Health 8:830-41. 2011
    ..As environmental public health studies pose uncertainties and potential risks, researchers need to do more to assess participants' understanding before assuming that individuals have given their 'informed' consent...
  52. ncbi Problem areas in the understanding of informed consent for research: study of middle-aged and older patients with psychotic disorders
    Laura B Dunn
    Department of Psychiatry, University of California, San Diego, CA 92161, USA
    Psychopharmacology (Berl) 171:81-5. 2003
    ..Optimizing the abilities of individuals with psychiatric disorders to provide meaningful informed consent for research has become a heightened concern for psychiatric researchers...
  53. ncbi Paying research subjects: an analysis of current policies
    Neal Dickert
    W G Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892 1156, USA
    Ann Intern Med 136:368-73. 2002
    ..Few data are available on guidelines used by research organizations to make decisions about paying subjects...
  54. ncbi Children as research subjects: moral disputes, regulatory guidance, and recent court decisions
    Loretta M Kopelman
    The Brody School of Medicine at East Carolina University, Greenville, NC 27858, USA
    Mt Sinai J Med 73:596-604. 2006
    ..Watershed events discussed include: First, the deaths of two research subjects, allegedly due to insufficient oversight by the investigators and their institutional review boards...
  55. ncbi What must research subjects be told regarding the results of completed randomized trials?
    Maurie Markman
    MD Anderson Cancer Center, Houston, Texas, USA
    IRB 26:8-10. 2004
  56. ncbi Medical students' perceptions of medical education research and their roles as participants
    Joseph P Forester
    Department of Anatomy, Philadelphia College of Osteopathic Medicine Georgia Campus, 625 Old Peachtree Road, Suwanee, GA 30024, USA
    Acad Med 80:780-5. 2005
    ..To better understand whether medical students perceive medical education research as important to their medical training and whether published opinions about why medical students participate in research are accurate...
  57. ncbi Consent forms in genomics: the difference between law and practice
    Paula Boddington
    HeLEX Centre for Health, Law and Emerging Technologies, Department of Public Health, University of Oxford, Oxford OX3 7LF, UK
    Eur J Health Law 18:491-519. 2011
    ..This raises questions about what should be put in informed consent forms for research participants. These findings could be beneficial for the formulation of participant information and consent documentation in the future studies...
  58. ncbi Focus group interviews examining attitudes toward medical research among the Japanese: a qualitative study
    Atsushi Asai
    Department of Biomedical Ethics, School of Public Health, Kyoto University Graduate School of Medicine, Konoe cho, Yoshido, Sakyo ku, Kyoto, Japan
    Bioethics 18:448-70. 2004
    ..Designs and Participants: fourteen Japanese adults from the general public and seven physicians participated in one of three focus interviews...
  59. ncbi Biodefence and the production of knowledge: rethinking the problem
    Allen Buchanan
    Duke University, Durham, NC, USA
    J Med Ethics 39:195-204. 2013
    ....
  60. ncbi Personal privacy, public benefits, and biobanks: a conjoint analysis of policy priorities and public perceptions
    Daryl Pullman
    Faculty of Medicine, Memorial University, St John s, Newfoundland, Canada
    Genet Med 14:229-35. 2012
    ..To assess the public's perception of biobank research and the relative importance they place on concerns for privacy and confidentiality, when compared with other key variables when considering participation in biobank research...
  61. pmc The legal risks of returning results of genomics research
    Ellen Wright Clayton
    Center for Biomedical Ethics and Society, Vanderbilt University, Nashville, Tennessee, USA
    Genet Med 14:473-7. 2012
    ..We confine our comments to research using data from large biobanks, the topic of the guidelines proposed in this symposium issue...
  62. pmc Procedure versus process: ethical paradigms and the conduct of qualitative research
    Kristian Pollock
    School of Nursing, Midwifery and Physiotherapy, University of Nottingham, Queen s Medical Centre, Derby Road, Nottingham NG7 2HA, UK
    BMC Med Ethics 13:25. 2012
    ....
  63. ncbi Pediatric assent: subject protection issues among adolescent females enrolled in research
    Theresa O'Lonergan
    Pediatric General Clinical Research Center at The Children s Hospital in Denver, USA
    J Law Med Ethics 34:451-9. 2006
  64. ncbi You have to make something of all that rubbish, do you? An empirical investigation of the social process of qualitative research
    Stacy M Carter
    Centre for Values, Ethics, and the Law in Medicine, University of Sydney, Sydney, New South Wales 2206, Australia
    Qual Health Res 18:1264-76. 2008
    ....
  65. ncbi Initial development of a questionnaire evaluating perceived benefits and barriers to pediatric clinical trials participation
    Lamia P Barakat
    The Children s Hospital of Philadelphia, USA
    Contemp Clin Trials 34:218-26. 2013
    ....
  66. ncbi Relationships with test-tubes: where's the reciprocity?
    Kelly Fryer-Edwards
    University of Washington School of Medicine, USA
    Am J Bioeth 6:36-8; author reply W10-2. 2006
  67. ncbi Exploitation in payments to research subjects
    Trisha Phillips
    Department of Philosophy and Religion, Mississippi State University, MS 39762, USA
    Bioethics 25:209-19. 2011
    Offering cash payments to research subjects is a common recruiting method but there is significant debate about whether and in what amount such payments are appropriate...
  68. ncbi Observed behaviors of subjects during informed consent for an emergency department study
    Jill Baren
    Department of Emergency Medicine, University of Pennsylvania School of Medicine, Ground Floor Ravdin Building, 3400 Spruce Street, Philadelphia, PA 19104 4283, USA
    Ann Emerg Med 55:9-14. 2010
    ..To determine emergency department patients' behaviors during informed consent for an intimate partner violence survey...
  69. pmc A randomized controlled trial of short and standard-length consent forms for a genetic cohort study: is longer better?
    Kenji Matsui
    Department of Preventive Medicine and Epidemiologic Informatics Office for Research Ethics, The National Cerebral and Cardiovascular Center, Suita, Osaka, Japan
    J Epidemiol 22:308-16. 2012
    ..there is little research on whether longer informed consent documents actually result in (1) better informed research subjects or (2) higher consent rates...
  70. ncbi How do children and parents make decisions about pediatric clinical research?
    Sumeeta Varma
    Department of Bioethics, National Institutes of Health Clinical Center, Bethesda, MD 20892, USA
    J Pediatr Hematol Oncol 30:823-8. 2008
    ..Investigators should be aware of and find ways to address these disagreements when soliciting assent from children...
  71. ncbi Moral reasoning and the review of research involving human subjects
    L Eckenwiler
    Old Dominion University, Norfolk, VA, USA
    Kennedy Inst Ethics J 11:37-69. 2001
    ..Most significant is a call for effective consultation with the various communities affected by research and greater reliance on subject representatives. Also proposed is national review for selected research...
  72. ncbi A pilot study to examine research subjects' perception of participating in research in the emergency department
    Carmen Paradis
    Cleveland Clinic, Department of Bioethics, Cleveland, Ohio 44195, USA
    J Med Ethics 36:580-7. 2010
    ..time constraints and sense of urgency that exists in the ED environment, concern exists about whether research subjects in the ED can provide full consent for participation...
  73. ncbi Justice in health research: What is the role of evidence-based medicine?
    Wendy Rogers
    Department of Philosophy, Macquarie University Sydney, Australia
    Perspect Biol Med 52:188-202. 2009
    ..This article examines flaws in the current processes of research production and the implications of these for justice and for vulnerable patients, and explores possible solutions...
  74. ncbi How well does South Africa's National Health Act regulate research involving children?
    Ann Strode
    Faculty of Law, University of KwaZulu Natal, Pietermaritzburg
    S Afr Med J 95:265-8. 2005
    ..We conclude that while the Act is an important development in the law, it is flawed in places. We recommend that amendments be made and that capacity development be provided to stakeholders...
  75. ncbi Compensation for injured research subjects
    Robert Steinbrook
    N Engl J Med 354:1871-3. 2006
  76. ncbi Unrelated hematopoietic stem cell donors as research subjects
    R J King
    National Marrow Donor Program, Minneapolis, MN, USA
    Bone Marrow Transplant 46:10-3. 2011
    ..World Marrow Donor Association calls on donor registries to participate in research activities. Here, we discuss various implications of research participation and make some recommendations as how to make this possible...
  77. ncbi Telephone survey respondents' reactions to questions regarding interpersonal violence
    Michele C Black
    Centers for Disease Control and Prevention Atlanta, GA 30341 3724, USA
    Violence Vict 21:445-59. 2006
    ..These results challenge commonly held beliefs and assumptions and provide some assurance to those concerned with the ethical collection of data on violent victimization...
  78. pmc The influence of risk and monetary payment on the research participation decision making process
    J P Bentley
    School of Pharmacy, The University of Mississippi, University, MS 38677, USA
    J Med Ethics 30:293-8. 2004
    ..To determine the effects of risk and payment on subjects' willingness to participate, and to examine how payment influences subjects' potential behaviours and risk evaluations...
  79. ncbi Reactions to research participation in vulnerable subgroups
    Cathy Spatz Widom
    Department of Psychiatry, New Jersey Medical School, 183 South Orange Avenue, BHSB F1406, Newark, NJ 07103, USA
    Account Res 12:115-38. 2005
    ..These results suggest that researchers and institutional review boards should not be deterred from conducting research on sensitive topics with potentially vulnerable populations...
  80. ncbi Assessing the quality of life of patients in phase I and II anti-cancer drug trials: interviews versus questionnaires
    Karen Cox
    Faculty of Medicine and Health Sciences, University of Nottingham, Medical School Room B50, Nottingham, UK
    Soc Sci Med 56:921-34. 2003
    ..The paper concludes by reflecting on some of the methodological issues that arise when assessing the quality of life of patients with a life threatening disease in clinical trials...
  81. ncbi Unconditional compensation: reducing the costs of disagreement about compensation for research subjects
    N Sofaer
    Program in Ethics and Health, Harvard University, Boston, Massachusetts, USA
    East Mediterr Health J 13:6-16. 2007
    ..We outline a research programme for assessing the potential of this practice to reduce costs...
  82. ncbi Comprehension during informed consent in a less-developed country
    Daniel W Fitzgerald
    Groupe Haitien d Etude du Sarcome de Kaposi et des Infections Opportunistes, Port au Prince, Haiti
    Lancet 360:1301-2. 2002
    ..Formal assessment of research participants' comprehension of the consent form should be considered as a routine step in the informed consent process in less-developed countries...
  83. ncbi When are research risks reasonable in relation to anticipated benefits?
    Charles Weijer
    Department of Bioethics, Dalhousie University, 5849 University Avenue, Halifax, Nova Scotia B3H 4H7, Canada
    Nat Med 10:570-3. 2004
  84. pmc Randomisation in trials: do potential trial participants understand it and find it acceptable?
    C Kerr
    Department of Psychology, Keele University, UK
    J Med Ethics 30:80-4. 2004
    ..To examine lay persons' ability to identify methods of random allocation and their acceptability of using methods of random allocation in a clinical trial context...
  85. pmc Managing incidental findings in human subjects research: analysis and recommendations
    Susan M Wolf
    University of Minnesota, MN, USA
    J Law Med Ethics 36:219-48, 211. 2008
    ..We recommend a pathway and categorize IFs into those that must be disclosed to research participants, those that may be disclosed, and those that should not be disclosed...
  86. pmc Toxic ignorance and right-to-know in biomonitoring results communication: a survey of scientists and study participants
    Rachel Morello-Frosch
    Department of Environmental Science, Policy and Management and School of Public Health, 137 Mulford Hall, University of California, Berkeley, Berkeley, CA 94720 3114, USA
    Environ Health 8:6. 2009
    ..This trend along with the paucity of health effect data for many of the pollutants studied raise ethical and scientific challenges for reporting results to study participants...
  87. ncbi Beyond informed consent: the therapeutic misconception and trust
    I de Melo-Martin
    Division of Medical Ethics, Department of Public Health, Weill Cornell Medical College, 411 E 69th Street, New York, NY, USA
    J Med Ethics 34:202-5. 2008
    ..participation from those receiving ordinary treatment may seriously undermine the informed consent of research subjects. Hence, most theoretical and empirical work on the problems of the therapeutic misconception has been ..
  88. ncbi Recent developments in the protection of pediatric research subjects
    Terence R Flotte
    Department of Pediatrics, Powell Gene Therapy Center, General Clinical Research Center, University of Florida, Gainesville, FL 32610, USA
    J Pediatr 149:285-286. 2006
  89. pmc DNA databanks and consent: a suggested policy option involving an authorization model
    Timothy Caulfield
    Primary Care Research Unit, Department of Family and Community Medicine, Joint Centre for Bioethics, University of Toronto, Toronto, M4N 3M5, Canada
    BMC Med Ethics 4:E1. 2003
    ..These databases rely on large numbers of research subjects contributing their genetic material to successfully explore the genetic basis of disease...
  90. ncbi Misusing informed consent: a critique of limitations on research subjects' access to genetic research results
    T M Banks
    Eberts Symes Street and Corbett
    Sask Law Rev 63:539-80. 2000
    ..Currently, the law of torts provides only weak protection for on-going disclosure for research subjects. The most substantive rights are to be found in the law of fiduciary obligations...
  91. ncbi The ethics of using QI methods to improve health care quality and safety
    Mary Ann Baily
    The Hastings Center, Garrison, NY 10524, USA
    Hastings Cent Rep 36:S1-40. 2006
  92. ncbi Moral conflict in clinical trials
    Maria Merritt
    Department of Clinical Bioethics, Warren G Magnuson Clinical Center of the National Institutes of Health, USA
    Ethics 115:306-30. 2005
  93. ncbi Reciprocity and post-trial access for participants in antiretroviral therapy trials
    Maria Merritt
    AIDS 20:1791-4. 2006
  94. pmc Developing capacity to protect human research subjects in a post-conflict, resource-constrained setting: procedures and prospects
    S B Kennedy
    Pacific Institute for Research and Evaluation PIRE, Louisville Center, 1300 S Fourth Street, Suite 300, Louisville, KY 40208, USA
    J Med Ethics 32:592-5. 2006
    ..Pacific Institute for Research and Evaluation (PIRE), to strengthen the system for the protection of human research subjects and the infrastructure of its international collaborating partner, the University of Liberia, are discussed...
  95. ncbi Perceptions of equipoise are crucial to trial participation: a qualitative study of men in the ProtecT study
    Nicola Mills
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, United Kingdom
    Control Clin Trials 24:272-82. 2003
    ..A priority for future research is to focus on the provision and presentation of suitable and effective trial information, concentrating in particular on the neglected concept of clinical equipoise...
  96. ncbi Misunderstanding in clinical research: distinguishing therapeutic misconception, therapeutic misestimation, and therapeutic optimism
    Sam Horng
    Harvard Medical School, USA
    IRB 25:11-6. 2003
  97. ncbi Exploitation in biomedical research
    David B Resnik
    Department of Medical Humanities, Brody School of Medicine, East Carolina University, Greenville, NC 27858, USA
    Theor Med Bioeth 24:233-59. 2003
    ..Calling a research project exploitative does not end the debate about the merits of the study but invites one to ask additional questions about how the study is exploitative, and whether the study is justifiable nevertheless...
  98. ncbi Informed consent: views from Karachi
    Aamir Jafarey
    Centre of Biomedical Ethics and Culture, Sindh Institute of Urology and Transplantation, Karachi, Pakistan
    East Mediterr Health J 12:S50-5. 2006
    ..When there was a conflict with the opinions of family leaders, it was clear that the male participants' opinion was valued more than that of the female participants by both men and women...
  99. ncbi Rethinking research ethics
    Rosamond Rhodes
    Mount Sinai School of Medicine
    Am J Bioeth 5:7-28. 2005
    ..These include: the primacy of informed consent, the protection of the vulnerable, the substitution of beneficence for research's social purpose, and the introduction of an untenable distinction between innovation and research...
  100. ncbi The research subject as wage earner
    James A Anderson
    Department of Bioethics, Dalhousie University, Halifax, Canada
    Theor Med Bioeth 23:359-76. 2002
    The practice of paying research subjects for participating in clinical trials has yet to receive an adequate moral analysis...
  101. ncbi Protecting the privacy of family members in survey and pedigree research
    J Botkin
    Primary Children s Medical Center, 100 N Medical Dr, Salt Lake City, UT 84113, USA
    JAMA 285:207-11. 2001
    ..The analysis suggests that strong protections for the rights and welfare of subjects and their family members can be incorporated into survey and pedigree research protocols without hindering projects with extensive consent requirements...

Research Grants73

  1. Non-Alcoholic Fatty Liver Disease and Obstructive Sleep Apnea: Mechanistic Links
    SHIKHA SEKSARIA SUNDARAM; Fiscal Year: 2013
    ..b>Research subjects will undergo testing of blood and urine for evidence of liver injury, metabolic abnormalities, oxidative ..
  2. DGAP: Developmental Genome Anatomy Project
    CYNTHIA CASSON MORTON; Fiscal Year: 2013
    ..In the first period of funding we identified a number of such genes in DGAP research subjects. In others, the mechanism of disruption does not directly break the gene but rather alters its regulation...
  3. Smart Home-based Health Platform for Behavioral Monitoring Diabetes and Obesity
    ABDELSALAM ALI HELAL; Fiscal Year: 2010
    ..researchers and practitioners, have long sought the ability to continuously and automatically monitor research subjects or patients for a variety of conditions or disorders...
  4. MEHARRY CLINICAL RESEARCH CENTER
    Valerie Rice; Fiscal Year: 2009
    ..A Research Subject Advocate (RSA) will ensure that the safety of research subjects is accorded the highest priority...
  5. Human neutralizing monoclonal antibodies for Rift Valley fever virus
    James E Crowe; Fiscal Year: 2013
    ..We have access to blood of survivors of RVF from East Africa. In addition, we have access to blood from research subjects who were previously inoculated with inactivated or MP-12 vaccine...
  6. Genome-wide genetic variation in the human immune response to influenza vaccines
    LUIS MIGUEL FRANCO; Fiscal Year: 2013
    ..oriented, as it will be conducted on humans and involves direct contact between the investigator and the research subjects. It is complemented by directly-related laboratory research, providing an opportunity for a career ..
  7. Cooperative Multicenter Reproductive Medicine Network UNC Clinical Site
    ANNE ZWEIFEL STEINER; Fiscal Year: 2013
    ..working collaboratively in our research endeavors and a solid track record of recruitment and retention of research subjects. The Division's clinical practice, UNC Fertility, offers a continuum of care from in-depth evaluation ..
  8. Genetic Variants of Human Carboxylesterase 1 Influence the Activation and Antivir
    John S Markowitz; Fiscal Year: 2012
    ..Other reports of deficient hCES1 activity by other research groups in research subjects have followed...
  9. IRIS: Incorporating Research Into Sight
    Catherine Anne McCarty; Fiscal Year: 2013
    ..2. Leverage GWAS data available for nearly 5000 research subjects aged 50 years and older in Marshfield and an additional 20-25,000 subjects throughout the eMERGE network to ..
  10. Managing Incidental Findings in the Genomic Era
    JANET K contact WILLIAMS; Fiscal Year: 2010
    ..Disclosing the prospect or discovery of genomic IFs to clinical patients or prospective research subjects is an area fraught with ethical, legal, social, and practical challenges...
  11. TB Guidline Observation and Adherence in Low Income Countries (TB GOAL)
    Adithya Cattamanchi; Fiscal Year: 2012
    ..The research subjects are the approximately 50 providers (3- 4 clinicians, 1-2 laboratory technicians, and 2-3 nurses per health ..
  12. Evolution &Maintenance of Memory CD8 T Cells
    KATHERINE F LUZURIAGA; Fiscal Year: 2013
    ..provide scientific leadership;manage fiscal affairs;collect, process, and disburse clinical specimens from research subjects;and develop and maintain a comprehensive clinical and laboratory database...
  13. Comparative Outcomes Management with Electronic Data Technology(COMET)Study
    Clete A Kushida; Fiscal Year: 2010
    ..that will enable the transfer of information from various hospitals and medical centers, patients and research subjects, different types and severity of medical problems, various equipment and test types, and across several ..
  14. Sterol and Isoprenoid Diseases Consortium
    ROBERT DAVID STEINER; Fiscal Year: 2013
    ..a long history of collaboration, a diverse geographic distribution to allow maximal access by potential research subjects, their individual motivation to improve the health of patients, and the commitment of their institution to ..
  15. Functional Mechanisms of Causal Variants in Systemic Lupus Erythematosus
    Patrick M Gaffney; Fiscal Year: 2013
    ..over 700 subjects of European and African ancestry, 3) an assembled database of over 1000 locally available research subjects broadly consented for participation in genetic studies and completely genotyped for all known SLE risk genes,..
  16. Research Ethics and Safety Promoted by Embodied Conversational Technology
    Michael Paasche-Orlow; Fiscal Year: 2013
    ..Despite decades of advocacy to improve informed consent for human subjects, multiple studies have shown that research subjects often do not understand fundamental concepts required for participation...
  17. Computerized Assessment by Remote Examiner System (CARES)
    JAMES P O'HALLORAN; Fiscal Year: 2011
    ..enable qualified clinicians to remotely conduct thorough neuropsychological or psychiatric evaluations of research subjects or patients with a range of acquired brain disorders for which such assessments are routinely applied, ..
  18. Eco-Pathogenomics of Chlamydial Reproductive Tract Infection (EPCRTI)
    Jacques Ravel; Fiscal Year: 2013
    ..Because of limitations in using humans as research subjects, guinea pigs are used as animal model for Chlamydial infections...
  19. HCV Replication and Immune Response in HIV Coinfection
    DAVID RICHARD GRETCH; Fiscal Year: 2010
    ..intrahepatic HCV replication and HCV QS variability in serum, liver and blood specimens collected from our research subjects on the same day...
  20. Mayo Clinic Urology O'Brien Research Center
    John C Lieske; Fiscal Year: 2012
    ..of this is that these advanced CT imaging techniques will allow physicians to more efficiently direct patient therapy and phenotype research subjects, potentially avoiding procedures associated with higher risk or cost.
  21. THYMIC TRANSPLANTATION IN COMPLETE DIGEORGE SYNDROME
    MARY LOUISE MARKERT; Fiscal Year: 2013
    ..Detailed evaluation of the research subjects will elucidate immune defects that remain in the subjects after transplantation which may allow improved ..
  22. Clinical Research Sites for the Network of Excellence in Neuroscience Clinical Tr
    TANYA SIMUNI SIMUNI; Fiscal Year: 2013
    ..Participation in NEXT will enable the NCTC to contribute expertise and research subjects to neurological clinical trials across multiple subspecialties in adult and pediatric populations, ..
  23. Characterizing the FASD cerebral cortex in utero with DTI
    Christopher D Kroenke; Fiscal Year: 2013
    ..Nonhuman primate research subjects will be bred after being trained to drink 1...
  24. Type 1 Diabetes TrialNet: Clinical Center at Berrie Center, Columbia University
    Robin S Goland; Fiscal Year: 2013
    ..The close geographic proximity of clinicians, scientists, patients, and clinical research subjects facilitates excellent and seamless collaboration and cross-fertilization and provides a unique and vibrant ..
  25. Enhancing Capacity in Human Subject Protections for Chinese Research Studies
    John M Falletta; Fiscal Year: 2010
    ..in the People's Republic of China to meet both their national standards for protecting human research subjects and international standards so that their research data are accepted widely...
  26. The Genetics of Hand Osteoarthritis Study (GHOST)
    MARIKO LISA ISHIMORI; Fiscal Year: 2013
    ..D., Director of the Division of Rheumatology at CSMC who is responsible for maintaining the CSMC registry of research subjects and has successfully recruited patients for major NIH-funded outcome studies in RA, OA, SLE, and AS...
  27. Oregon Alzheimer's Disease Center
    Jeffrey A Kaye; Fiscal Year: 2013
    ..The Clinical Core provides well-characterized, longitudinally followed research subjects of several kinds: 1) early AD and related dementias;2) non-cognitively impaired or MCI elderly at high risk ..
  28. Serial Passage: AIDS, Race, and Culture Phase II
    CLAUDIA PRYOR; Fiscal Year: 2009
    ..They are also research subjects. An interim evaluation report showed a dramatic increase in the students'perceived knowledge of HIV/..
  29. Technology to Automatically Detect Falls and Assess Fall Risk in Senior Housing
    Marilyn J Rantz; Fiscal Year: 2012
    ..methods require that research staff or clinicians complete multi-factorial assessments of fall risk and that research subjects maintain logs of falls, wear devices that measure changes in positions that could indicate a fall or ..
  30. MULTIPLEXED ECHO PLANAR IMAGING FOR NEUROSCIENCES
    DAVID ALAN FEINBERG; Fiscal Year: 2013
    ..from 25 minutes to 8 or 12 minutes scans and these scan times will be more tolerable by both patients and research subjects. The multiplexed EPI can scan many times faster or instead be used to provide more images that are thinner ..
  31. Testing Modified Approaches to Informed Consent
    Nancy E Kass; Fiscal Year: 2010
    ..In theory, this paradigm has significant moral merit. In practice, however, evidence suggests many research subjects do not understand the primary purpose or key procedures of studies in which they enroll...
  32. MULTICENTER NETWORK OF MATERNAL FETAL MEDICINE UNITS
    Steve N Caritis; Fiscal Year: 2013
    ..37 private OB/GYN physicians were acquired by the Department of OB/GYN dramatically increasing our access to research subjects. To further enhance our population base, in May 2010,we initiated a collaborative agreement with the only ..
  33. Hign Performance MEMS Deformable Mirror for Adaptive Optics Retinal Imaging
    MICHAEL HELMBRECHT; Fiscal Year: 2009
    ..will enable in vivo imaging of cellular structure to be done on the general populace instead of hand-picked research subjects as is the practice today...
  34. SPF BREEDING COLONIES AT THE YERKES NPRC: AIDS, GENOME
    JAMES GIBSON ELSE; Fiscal Year: 2011
    ..pathogen free (SPF- as defined by NCRR in RFA RR-G2-005), MHC typed and genetically characterized to provide research subjects to NIH supported investigators for AIDS related research...
  35. Describing Variation in IRB Efficiency, Quality and Procedures
    Daniel E Hall; Fiscal Year: 2013
    ..05. Despite the VA's commitment to ensure the protection of human research subjects, there is variation in the quality and efficiency of research oversight in the VA...
  36. A High-Field Small Animal MR Imager for Biomedical Research
    CHARLES DENNIS SMITH; Fiscal Year: 2010
    ..Center (MRISC) will facilitate translation of imaging protocols between experimental animals and human research subjects and will aid in the acquisition of optimal imaging protocols on complex studies...
  37. American Indian Diabetes Prevention Center: Impacting Health Disparity in Youth
    JOSEPH NEIL HENDERSON; Fiscal Year: 2013
    ..3) conduct education on diabetes to Al adults with integrated encouragement to serve as health disparities research subjects. The Community Engagement/Outreach Core will 1) conduct a Youth Asset building program using community, ..
  38. Controlling Human Aging: Alternative Rationales and Implications
    Eric T Juengst; Fiscal Year: 2010
    ..Lay Descripton: We propose to study the ways in which scientists, research subjects, clinicians and consumers explain their interests in controlling the human aging process, in order to help ..
  39. HIV/AIDS NURSING CARE AND PREVENTION
    David Vlahov; Fiscal Year: 2013
    ..Both pre- and postdoctoral trainees are trained in issues related to the protection of human research subjects and HIPAA...
  40. Challenges of Informed Consent in Return of Data from Genomic Research
    PAUL STUART APPELBAUM; Fiscal Year: 2012
    ..incidental to the purpose for which a study is undertaken, can contain information of use and importance to research subjects related to their health, lifestyle, and reproductive choices...
  41. HIV Microbicides and the Vaginal Microbiome
    Steven Zeichner; Fiscal Year: 2009
    ..Unfortunately, several large late phase trials of HIV microbicides have failed for unknown reasons, with the research subjects using the microbicides having rates of HIV transmission higher than subjects using placebos...
  42. Clinical Center for the Parkinson Disease Neuroprotection Clinical Trial
    Ramon L Rodriguez; Fiscal Year: 2013
    ..Our primary objectiv with this project will be to retain the currently enrolled research subjects in the neuroprotection pilot study LS-1, as well as continue participation in subsequent phase III trials ..
  43. Community Cancer Genetics and Research Training (Revision)
    Jeffrey Weitzel; Fiscal Year: 2009
    ..Consequently, a substantial number of potential clinical research subjects may not be realized...
  44. PREPARATION FOR AIDS/HIV VACCINE EVALUATIONS
    Susan Allen; Fiscal Year: 1993
    ..Infrastructures for recruitment and followup of research subjects have been established, and laboratory capacities include serology and PCR for HIV...
  45. DEVELOPMENT OF A SPF PIGTAIL MACAQUE BREEDING COLONY
    ROBERT DRUILHET; Fiscal Year: 2000
    ..viral agents occur naturally in these macaques, and their presence makes the affected animal unsuitable as research subjects for AIDS-related projects and other viral infectious disease and vaccine research...
  46. A MODULAR SHORT COURSE IN RESEARCH ETHICS
    Caroline Whitbeck; Fiscal Year: 2000
    ..Sharing, and Interpretation of Data, and on Ethics and Equity in the Selection of Populations Recruited as Research Subjects will be drafted and reviewed this summer and offered on a pilot basis at least once in the fall...
  47. A MODULAR SHORT COURSE IN RESEARCH ETHICS
    Caroline Whitbeck; Fiscal Year: 2001
    ..Sharing, and Interpretation of Data, and on Ethics and Equity in the Selection of Populations Recruited as Research Subjects will be drafted and reviewed this summer and offered on a pilot basis at least once in the fall...
  48. South American Prevention of HIV Research Training Program (SAPHIR)
    Ronald T Mitsuyasu; Fiscal Year: 2013
    ..ethical conduct of research with human subjects as defined by the UCLA Committee for the Protection of Human Research Subjects;5) Submit a funding proposal for peer review and receive a written summary statement;and 6) Present results ..
  49. RESEARCH TRAINING IN TRANSFUSION MEDICINE
    II WHITE; Fiscal Year: 2012
    ..Research Opportunities available to trainees cover a broad range of clinical and basic research subjects relevant to transfusion science, including Immunology, Vascular Biology/Hemostasis, Transfusion Medicine, ..
  50. NINDS Center Core for Brain Imaging
    DANIEL SCOTT MARCUS; Fiscal Year: 2013
    ..Neuroimaging studies have become more expansive in terms of the number of research subjects involved, the types of image acquisitions utilized in protocols, the diversity of non-imaging measures that ..
  51. Resetting Nutritional Defaults: Testing the Effect of NuVal on Older Adults
    Linda G Snetselaar; Fiscal Year: 2012
    ..post- NuValTM intervention shopping behavior of a group of eastern Iowans age 50 and over, who are volunteer research subjects in the University of Iowa's STAR Registry, to obtain information on the NuValTM intervention's ..
  52. Automated Web-Based Behavioral Diagnostics of Cognitive Impairment
    YEVGENY EUGENE AGICHTEIN; Fiscal Year: 2013
    ..This would enable thousands and potentially millions of patients and potential research subjects to take the test as part of their routine checkup, requiring nothing more than a computer with an internet ..
  53. SPIROMICS Genomics & Informatics Center (GIC)
    Lisa Lavange; Fiscal Year: 2010
    ..b>Research subjects will be enrolled, phenotyped, and followed at approximately six Clinical Centers (CCs)...
  54. SUBPOPULATIONS AND INTERMEDIATE OUTCOME MEASURES IN COPD STUDY (SPIROMICS): BRON
    Graham Barr; Fiscal Year: 2011
    ..b>Research subjects will be enrolled, phenotyped, and followed at approximately six Clinical Centers (CCs)...
  55. SPIROMICS Radiology Center
    Eric Hoffman; Fiscal Year: 2009
    ..b>Research subjects will be enrolled, phenotyped, and followed at approximately six Clinical Centers (CCs)...
  56. Bridges to Sucess in the Sciences
    GEZA GABOR VARHEGYI; Fiscal Year: 2012
    ..Students are required to complete and become certified in the Protection of Human Research Subjects through a course given at Case Western Reserve University...
  57. AN INTRA-ORAL SALIVA VACUUMING APPLIANCE FOR SIALORRHEA
    Carrie Brown; Fiscal Year: 2000
    ..8-10 research subjects with saliva overflow problems will be assigned to two groups and test each of the prototypes for 4 months...
  58. INFORMED CONSENT FOR STUDIES INVOLVING SURGICAL PATIENTS
    ALAN TAIT; Fiscal Year: 2002
    ..Furthermore, our preliminary studies suggest that many research subjects do not fully understand all the elements of the informed consent document...
  59. SPEECH PROCESSORS FOR AUDITORY PROSTHESES
    BLAKE WILSON; Fiscal Year: 2000
    ..The test score results from many of these research subjects have shown significant increases over scores achieved with their conventional commercial processors even ..
  60. ISOFLAVONE-RICH PASTA--CLINICAL AND COMMERCIAL POTENTIAL
    RICHARDUS ROSS; Fiscal Year: 2000
    ..Compliance to a soy-based diet in demographically diverse clinical research subjects or dietary changes in the general population is desirable but unlikely to be achieved by use of traditional ..
  61. Ethics in Behavioral Health Services Research
    Paul Stiles; Fiscal Year: 2005
    ..that arise when vulnerable populations, particularly people with severe mental disabilities, are used as research subjects. Issues addressed include historical foundations; informed consent; decisional capacity and competency; ..
  62. CHILDREN AS RESEARCH SUBJECTS: HISTORY AND ETHICS
    PAUL EDELSON; Fiscal Year: 2001
    ..involves carrying out a historical analysis of six examples of clinical trials in which children were research subjects: the trial of diphtheria antitoxin treatment (1895), the Salk vaccine trial (1954), the development of ..
  63. FHCRC-Human Subjects Research Enhancements Program
    Barry Storer; Fiscal Year: 2003
    ..This project will focus on enhancing the protection of human research subjects in two regions with active HVTN programs at four international sites (Botswana, Dominican Republic, Republic ..
  64. The Blurring of Treatment and Research in Clinical Trials: two problems
    Charles W Lidz; Fiscal Year: 2010
    ....
  65. SCCISARS 2: An e-Solution to Protect Human Subjects
    Darcy Spicer; Fiscal Year: 2003
    ..Angeles (CHLA) are collaborating on electronic software to enhance the systems for the protection of human research subjects, the University of Southern California and Childrens Hospital Los Angeles IRB Submission and Review System, (..
  66. Research Enhancements and Administration Project
    Barbara Barnes; Fiscal Year: 2003
    The broad objective of this project is to enhance the protection of human research subjects by maximizing the institutional capacity for the education and training of individuals who are involved in human subject research at the ..
  67. AN ETHNOGRAPHIC STUDY OF INSTITUTIONAL REVIEW BOARDS
    Raymond DeVries; Fiscal Year: 2002
    ..Institutional Review Boards were created to protect humans from exploitation as research subjects. Although there is near universal agreement that IRBs have been an important tool for the protection of ..