- Genetic variation and population structure in native Americans
The Galton Laboratory, Department of Biology, University College London, London, United Kingdom
PLoS Genet 3:e185. 2007
..These findings offer new insights into the process of population dispersal and differentiation during the peopling of the Americas...
- Distinctive Paleo-Indian migration routes from Beringia marked by two rare mtDNA haplogroups
Ugo A Perego
Dipartimento di Genetica e Microbiologia, Universita di Pavia, 27100 Pavia, Italy
Curr Biol 19:1-8. 2009
..In this study, we have instead identified and analyzed mtDNAs belonging to two rare Native American haplogroups named D4h3 and X2a...
- Y-chromosome evidence for differing ancient demographic histories in the Americas
Maria Catira Bortolini
Department of Biology, University College, London, United Kingdom
Am J Hum Genet 73:524-39. 2003
..Age estimates based on Y-chromosome microsatellite diversity place the initial settlement of the American continent at approximately 14,000 years ago, in relative agreement with the age of well-established archaeological evidence...
- Genetic and environmental contributions to cardiovascular disease risk in American Indians: the strong heart family study
Kari E North
Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX, USA
Am J Epidemiol 157:303-14. 2003
..34)). These results suggest that heredity explains a substantial proportion of the variability of CVD risk factors and that these heritabilities are large enough to warrant a search for major risk factor genes...
- Beringian standstill and spread of Native American founders
Department of Evolutionary Biology, University of Tartu, Estonian Biocentre, Tartu, Estonia
PLoS ONE 2:e829. 2007
..This pause in movement was followed by a swift migration southward that distributed the founder types all the way to South America. The data also suggest more recent bi-directional gene flow between Siberia and the North American Arctic...
- Genetic origins of anxiety in women: a role for a functional catechol-O-methyltransferase polymorphism
MARY ANNE ENOCH
Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA
Psychiatr Genet 13:33-41. 2003
- The dual origin and Siberian affinities of Native American Y chromosomes
Jeffrey T Lell
Center for Molecular Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Am J Hum Genet 70:192-206. 2002
..This migration event contributed to the modern genetic pool of the Na-Dene and Amerinds of North and Central America...
- Obesity prevention in preschool native-american children: a pilot study using home visiting
Department of Nutrition and Food, Sciences University of Vermont, Burlington, Vermont 05405 0148, USA
Obes Res 11:606-11. 2003
- A private allele ubiquitous in the Americas
K B Schroeder
Department of Anthropology, University of California, Davis, CA 95616, USA
Biol Lett 3:218-23. 2007
..The simplest explanation for the ubiquity of this allele across the Americas is that the same founding population contributed a large fraction of ancestry to all modern Native American populations...
- The embodiment of inequity: health disparities in aboriginal Canada
Department of Anthropology, York University, Toronto, ON
Can J Public Health 96:S45-61. 2005
..Research and policy must address the contemporary realities of Aboriginal health and well-being, including the individual and community-based effects of health disparities and the direct and indirect sources of those disparities...
- The use of maximum likelihood methods to estimate the risk of tuberculous infection and disease in a Canadian First Nations population
First Nations and Inuit Health Branch, Health Canada, Ottawa, Canada
Int J Epidemiol 33:477-84. 2004
..The epidemiology of tuberculous infection and disease during the period 1926-2000 in this population was investigated...
- Pathways: a culturally appropriate obesity-prevention program for American Indian schoolchildren
S M Davis
University of New Mexico, School of Medicine, Center for Health Promotion and Disease Prevention, Albuquerque 87131 5311, USA
Am J Clin Nutr 69:796S-802S. 1999
- Disparities in chronic disease risk factors and health status between American Indian/Alaska Native and White elders: findings from a telephone survey, 2001 and 2002
Clark H Denny
Cardiovascular Health Branch, Division of Adult and Community Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Public Health 95:825-7. 2005
..For all health behavior and status measures, American Indians/Alaska Natives reported greater risk than did Whites. Risk factors among AIAN elders need to be addressed to eliminate disparities in chronic diseases...
- Reducing diabetes risk in American Indian women
Janice L Thompson
Office of Native American Diabetes Programs, Department of Internal Medicine, School of Medicine, The University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA
Am J Prev Med 34:192-201. 2008
..American Indians experience high rates of type 2 diabetes. The impact of low-intensity interventions on diabetes risk among young American Indian women is unknown...
- Racial and ethnic differences in trends of end-stage renal disease: United States, 1995 to 2005
Nilka Rios Burrows
Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
Adv Chronic Kidney Dis 15:147-52. 2008
..The disparity gap in ESRD incidence between minority populations and whites narrowed during 1995 to 2005. Continued interventions to reduce the prevalence of ESRD risk factors are needed to decrease ESRD incidence...
- A genomewide single-nucleotide-polymorphism panel for Mexican American admixture mapping
Rowe Program in Human Genetics, Department of Biochemistry, University of California Davis, Davis, CA 95616, USA
Am J Hum Genet 80:1014-23. 2007
..The results will enable studies of type 2 diabetes, rheumatoid arthritis, and other diseases among which epidemiological studies suggest differences in the distribution of ancestry-associated susceptibility...
- Y-chromosome biallelic polymorphisms and Native American population structure
M C Bortolini
Departamento de Genetica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
Ann Hum Genet 66:255-9. 2002
..Furthermore, they underline the importance of genetic drift in the evolution of Amerinds and suggest the existence of a North to South gradient of increasing drift in the Americas...
- Problematic use of Greenberg's linguistic classification of the Americas in studies of Native American genetic variation
Deborah A Weiss Bolnick
Am J Hum Genet 75:519-22. 2004
- Prevalence of diabetes among Native Americans and Alaska Natives, 1990-1997: an increasing burden
N R Burrows
Headquarters Diabetes Program, Indian Health Service, Atlanta, Georgia, USA
Diabetes Care 23:1786-90. 2000
..To determine trends in diabetes prevalence among Native Americans and Alaska Natives...
- Tobacco, alcohol, and illicit drug use: racial and ethnic differences among U.S. high school seniors, 1976-2000
John M Wallace
University of Michigan, Institute for Social Research, 426 Thompson Street, Ann Arbor, MI 48106 1248, USA
Public Health Rep 117:S67-75. 2002
..This study examines differences in adolescents' use of tobacco, alcohol, and illicit drugs by racial and ethnic groups...
- The cost of major comorbidity in people with diabetes mellitus
Scot H Simpson
Institute of Health Economics, Edmonton, Alta
CMAJ 168:1661-7. 2003
..Information on the economic impact of diabetes and its complications on the Canadian health care system is limited...
- Common Polymorphisms in the Adiponectin Gene ACDC Are Not Associated With Diabetes in Pima Indians
Barbora Vozarova de Courten
Translational Genomics Research Institute, Diabetes Research Unit, NIDDK, NIH, 400 North 5th St, Phoenix, Arizona, USA
Diabetes 54:284-9. 2005
..Our findings suggest that these common ACDC polymorphisms do not play a major role in susceptibility to obesity or type 2 diabetes in this population...
- Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant
Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, Phoenix, AZ, USA
Diabetes 57:3267-72. 2008
..Humans with functional variants in the melanocortin 4 receptor (MC4R) are obese, hyperphagic, and hyperinsulinemic but have been reported to have no difference in energy expenditure...
- Review of research on aboriginal populations in Canada: relevance to their health needs
T Kue Young
Department of Public Health Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada M5S 1A8
BMJ 327:419-22. 2003
..To determine if research has adequately examined the health needs of the aboriginal population of Canada...
- Body mass index and blood pressure screening in a rural public school system: the Healthy Kids Project
William E Moore
University of Oklahoma Prevention Research Center, Oklahoma City, OK 73104, USA
Prev Chronic Dis 3:A114. 2006
- Interpersonal violence in the lives of urban American Indian and Alaska Native women: implications for health, mental health, and help-seeking
Institute for Indigenous Health and Child Welfare Research, School of Social Work, University of Washington, Seattle 98105, USA
Am J Public Health 96:1416-22. 2006
- Increasing prevalences of overweight and obesity in Northern Plains American Indian children
Aberdeen Area Indian Health Service, Aberdeen, SD, USA
Arch Pediatr Adolesc Med 160:34-9. 2006
..To report prevalences of overweight and obesity in a large sample of American Indian children from a survey in 2002-2003, and to evaluate the change in prevalences since 1995-1996 when children on the same reservations were measured...
- The epidemiology of diabetes in the Manitoba-registered First Nation population: current patterns and comparative trends
Epidemiology Unit, Manitoba Health, Winnipeg, Canada
Diabetes Care 26:1993-8. 2003
..This study provides an overview of the epidemiology of diabetes in the Manitoba First Nation population...
- Risk factors, atherosclerosis, and cardiovascular disease among Aboriginal people in Canada: the Study of Health Assessment and Risk Evaluation in Aboriginal Peoples (SHARE-AP)
S S Anand
Preventive Cardiology and Therapeutics Research Program, Department of Medicine, McMaster University, Ontario, L8L 2X2, Hamilton, Canada
Lancet 358:1147-53. 2001
..To establish the relative prevalence of risk factors, atherosclerosis, and CVD, we undertook a population-based study among people of Aboriginal and European ancestry in Canada...
- Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians
Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
Diabetes 58:478-88. 2009
..We investigated the association of these single nucleotide polymorphisms (SNPs) and some additional tag SNPs with type 2 diabetes and related quantitative traits in Pima Indians...
- Rapid deployment of the five founding Amerind mtDNA haplogroups via coastal and riverine colonization
Alan G Fix
Department of Anthropology, University of California, Riverside, California 92521, USA
Am J Phys Anthropol 128:430-6. 2005
..The present paper demonstrates through a computer simulation model how colonization along coasts and rivers could have rapidly spread the founding lineages widely through North America...
- Racial inequality in active life among adult Americans
M D Hayward
Department of Sociology, Pennsylvania State University, University Park 16802, USA
Demography 36:77-91. 1999
..Racial differences in the link between morbidity and mortality point to the importance of investigating how chronic diseases and disease prevention and treatment are related to active life across the population subgroups...
- Brief communication: molecular analysis of the Kwäday Dän Ts'finchi ancient remains found in a glacier in Canada
M Victoria Monsalve
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 2B5, Canada
Am J Phys Anthropol 119:288-91. 2002
- The epidemic of obesity in American Indian communities and the need for childhood obesity-prevention programs
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
Am J Clin Nutr 69:747S-754S. 1999
..To be most effective, interventions must be developed with full participation of the American Indian communities...
- Incidence of lower-extremity amputation in American Indians: the Strong Heart Study
Helaine E Resnick
Department of Epidemiology and Statistics, MedStar Research Institute, 6495 New Hampshire Ave, Suite 201, Hyattsville, MD 20783, USA
Diabetes Care 27:1885-91. 2004
..To define incidence and predictors of nontraumatic lower-extremity amputation (LEA) in a diverse cohort of American Indians with diabetes...
- Beverage consumption and risk of obesity among Native Americans in Arizona
Christopher M Wharton
Department of Nutrition, Arizona State University, 7001 E Williams Field Rd, Mesa, AZ 85212, USA
Nutr Rev 62:153-9. 2004
..Prevention programs that target pregnant women and parents of infants and very young children are necessary to halt the epidemic of obesity among Native Americans; one approach may be by promoting sugar-free beverages...
- Evidence for distinct genetic effects on obesity and lipid-related CVD risk factors in diabetic compared to nondiabetic American Indians: the Strong Heart Family Study
Kari E North
Department of Epidemiology, University of North Carolina, Chapel Hill, Bank of America Center, North Carolina 27514 3628, USA
Diabetes Metab Res Rev 19:140-7. 2003
..The purpose of the present paper is to determine whether the genetic effects on CVD risk factors in the SHFS are different in diabetic and nondiabetic individuals...
- Auditory P3 findings in mission Indian youth
C L Ehlers
Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037, USA
J Stud Alcohol 62:562-70. 2001
..In this study, the amplitude of the P3 component of the event-related potential (ERP), a measure associated with risk for alcoholism in European-American youth, was investigated in Mission Indians...
- Asthma prevalence among American Indian and Alaska Native children
J W Stout
University of Washington, Seattle, USA
Public Health Rep 114:257-61. 1999
..The authors used the latest available household survey data to estimate the prevalence of asthma in this population...
- Countries of ancestry reported by hemochromatosis probands and control subjects in central Alabama
Ellen H Barton
University of Alabama at Birmingham, Southern Iron Disorders Center, Birmingham, Alabama, USA
Ethn Dis 14:73-81. 2004
..0896) is due to a predominance of persons of Irish and Scots descent, and is not attributable to Native American ancestry common in this geographic area...
- Organochlorines, lead, and mercury in Akwesasne Mohawk youth
Lawrence M Schell
Department of Epidemiology, University at Albany, State University of New York, Albany, New York 12222, USA
Environ Health Perspect 111:954-61. 2003
- Mitochondrial DNA diversity in indigenous populations of the southern extent of Siberia, and the origins of Native American haplogroups
Elena B Starikovskaya
Laboratory of Human Molecular Genetics, Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, Novosibirsk 630090, Russia Federation
Ann Hum Genet 69:67-89. 2005
- Prevalence of asthma and chronic respiratory symptoms among Alaska Native children
Toby C Lewis
Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, MI, USA
Chest 125:1665-73. 2004
..To quantify the prevalence and impact of chronic respiratory symptoms among predominantly Alaska Native (AN)/American Indian (AI) middle school students...
- Linkage analysis of LDL cholesterol in American Indian populations: the Strong Heart Family Study
K E North
Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA
J Lipid Res 47:59-66. 2006
..Suggestive evidence of linkage to LDL-C was detected on chromosomes 3q, 4q, 7p, 9q, 10p, 14q, and 17q. These linkage signals overlap positive findings for lipid-related traits and harbor plausible candidate genes for LDL-C...
- Traditional foods and physical activity patterns and associations with cultural factors in a diverse Alaska Native population
Diana G Redwood
Alaska Native Tribal Health Consortium, Anchorage, Alaska, USA
Int J Circumpolar Health 67:335-48. 2008
- Height, weight, and body mass index among Akwesasne Mohawk youth
Mia V Gallo
Department of Anthropology, University at Albany, State University of New York, Albany, NY 12222, USA
Am J Hum Biol 17:269-79. 2005
..The potential for long-term health effects associated with being overweight has implications for the future health of young Native Americans...
- Diabetes susceptibility in the Canadian Oji-Cree population is moderated by abnormal mRNA processing of HNF1A G319S transcripts
Lorna W Harries
Institute of Biomedical and Clinical Sciences, Peninsula Medical School, Exeter, U K
Diabetes 57:1978-82. 2008
..We hypothesized that the variant site at the 3' end of exon 4 might influence splicing and characterized mRNA transcripts to investigate the mutational mechanism underlying this susceptibility to diabetes...
- Native American mtDNA prehistory in the American Southwest
Ripan S Malhi
Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA
Am J Phys Anthropol 120:108-24. 2003
..Southern Athapaskans probably experienced a bottleneck followed by extensive admixture during the migration to their current homeland in the Southwest...
- Diabetes mellitus in the First Nations population of British Columbia, Canada. Part 2. Hospital morbidity
Health Canada, First Nations and Inuit Health Branch, Pacific Region, Vancouver, Canada
Int J Circumpolar Health 61:254-9. 2002
..To describe hospitalization rates from diabetes mellitus or its complications among residents of the province of British Columbia, Canada during the 5-year period 1993 to 1997, comparing people with Indian Status to rest of the population...
- The structure of diversity within New World mitochondrial DNA haplogroups: implications for the prehistory of North America
Ripan S Malhi
Department of Human Genetics, 3726 Medical Science II, University of Michigan, 1301 E Catherine Street, Ann Arbor, MI 48109 0618, USA
Am J Hum Genet 70:905-19. 2002
..The hypervariability and reticulation preclude the use of estimates of genetic diversity within haplogroups to argue for the number of migrations to the Americas...
- Diabetes in relation to serum levels of polychlorinated biphenyls and chlorinated pesticides in adult Native Americans
Department of Epidemiology and Statistics, School of Public Health, University at Albany, Rensselaer, New York 12144 3429, USA
Environ Health Perspect 115:1442-7. 2007
..Recent research suggests that diabetes, a condition whose incidence is increasing, is associated with exposure to polychlorinated biphenyls (PCBs) and chlorinated pesticides...
- Intrafamilial correlates of overweight and obesity in African-American and Native-American grandparents, parents, and children in rural Oklahoma
Diana C Polley
Langston University, 1412 Woodbury Circle, Edmond, Oklahoma 73034, USA
J Am Diet Assoc 105:262-5. 2005
- The health of Cree, Inuit and southern Quebec women: similarities and differences
Santé Québec Division, Institut de la statistique du Québec, Montreal
Can J Public Health 91:212-6. 2000
..The similarities and differences observed among these three populations of women can assist decision-makers in setting priorities with regards to maintaining and improving their health...
- Ancient mitochondrial DNA evidence for prehistoric population movement: the Numic expansion
F A Kaestle
Department of Anthropology, Yale University, New Haven, Connecticut 06520, USA
Am J Phys Anthropol 115:1-12. 2001
..The distribution of mitochondrial haplogroups of the ancient inhabitants of the Great Basin is most similar to those of some of the modern Native American inhabitants of California...
- Public health and clinical implications of high hemoglobin A1c levels and weight in younger adult Native American people with diabetes
J S Carter
Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
Arch Intern Med 160:3471-6. 2000
..Because glycemic levels are predictive of diabetes outcome, understanding determinants of high hemoglobin A(1c) (HbA(1c)) levels may provide targets for prevention efforts...
- Commentary: quality of alcohol, drug, and mental health services for American Indian children and adolescents
D K Novins
Faculty of the National Center for American Indian and Alaska Native Mental Health Research, University of Colorado Health Sciences Center, Denver 80210
Am J Med Qual 15:148-56. 2000
..We then consider the implications of these studies for improving the quality of care as well as its measurement and monitoring...
- The late Pleistocene dispersal of modern humans in the Americas
Center for the Study of the First Americans, Department of Anthropology, Texas A and M University, 4352 TAMU, College Station, TX 77843 4352, USA
Science 319:1497-502. 2008
..If this is the time of colonization, geological data from western Canada suggest that humans dispersed along the recently deglaciated Pacific coastline...
- Use of biomedical services and traditional healing options among American Indians: sociodemographic correlates, spirituality, and ethnic identity
Douglas K Novins
Med Care 42:670-9. 2004
..The objective of this study was to describe the use of biomedical services and traditional healing options among a reservation-based sample of American Indians from 2 culturally distinct tribes..
- TCF7L2 is not a major susceptibility gene for type 2 diabetes in Pima Indians: analysis of 3,501 individuals
Diabetes Molecular Genetics Section, Phoenix Epidemiology and Clinical Research Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, NIH, 445 North 5th St, Phoenix, AZ 85004, USA
Diabetes 56:3082-8. 2007
..S. populations. We investigated whether TCF7L2 also has a role in type 2 diabetes susceptibility in Pima Indians...
- A single and early migration for the peopling of the Americas supported by mitochondrial DNA sequence data
S L Bonatto
Departamento de Genetica, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
Proc Natl Acad Sci U S A 94:1866-71. 1997
- A genomewide admixture mapping panel for Hispanic/Latino populations
Department of Anthropology, The Pennsylvania State University, University Park, PA 16801, USA
Am J Hum Genet 80:1171-8. 2007
..This genomewide AM panel will make it possible to apply AM approaches in many admixed populations throughout the Americas...
- Long-term efficacy of BCG vaccine in American Indians and Alaska Natives: A 60-year follow-up study
Naomi E Aronson
Department of Medicine, Infectious Disease Division, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
JAMA 291:2086-91. 2004
..The duration of protection from tuberculosis of BCG vaccines is not known...
- Rising tide of cardiovascular disease in American Indians. The Strong Heart Study
B V Howard
Medlantic Research Institute and Washington Hospital Center, Washington, DC, USA
Circulation 99:2389-95. 1999
..The Strong Heart Study was initiated to investigate CVD and its risk factors in American Indians in 13 communities in Arizona, Oklahoma, and South/North Dakota...
- Low recognition of childhood overweight and disease risk among Native-American caregivers
Alexandra K Adams
Department of Family Medicine, University of Wisconsin Madison, 777 South Mills Street, Madison, WI 53715, USA
Obes Res 13:146-52. 2005
..We also assessed caregiver attributes associated with levels of concern for risk of future overweight and chronic disease...
- High serum PCBs are associated with elevation of serum lipids and cardiovascular disease in a Native American population
Institute for Health and the Environment, University at Albany, 5 University Place, A217, Rensselaer, NY 12144 3429, USA
Environ Res 106:226-39. 2008
- Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an American Indian population
J C Long
Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20892 8110, USA jeff
Am J Med Genet 81:216-21. 1998
..8) on chromosome 4p, near the beta1 GABA receptor gene. Interestingly, three loci in the alcohol dehydrogenase gene cluster on chromosome 4q showed evidence for linkage with two-point analyses, but not multipoint analysis...
- Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian
Diabetes and Arthritis Epidemiology Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014, USA
Diabetes Care 26:1745-51. 2003
- Variants in the Ca V 2.3 (alpha 1E) subunit of voltage-activated Ca2+ channels are associated with insulin resistance and type 2 diabetes in Pima Indians
Yunhua Li Muller
Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, 455 North 5th St, Phoenix, AZ 85004, USA
Diabetes 56:3089-94. 2007
..CACNA1E encodes the voltage-dependent calcium channel Ca(v)2.3 Ca(2+), and mice lacking this channel exhibit impaired glucose tolerance and insulin secretion. Therefore, CACNA1E was investigated as a positional candidate gene...
- Complications of Type 2 Diabetes Among Aboriginal Canadians: prevalence and associated risk factors
Anthony J G Hanley
Leadership Sinai Centre for Diabetes, Lebovic Building, Room 5 210, Mt Sinai Hospital, 600 University Ave, Toronto, Ontario, M5G 1X5, Canada
Diabetes Care 28:2054-7. 2005
- Commitment of the National Institute of Environmental Health Sciences to community-based participatory research for rural health
L R O'Fallon
Division of Extramural Research and Training, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
Environ Health Perspect 109:469-73. 2001
..We conclude with a discussion of future plans for community-based participatory research at NIEHS...
- Surveillance for health behaviors of American Indians and Alaska Natives. Findings from the Behavioral Risk Factor Surveillance System, 1997-2000
Clark H Denny
Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, CDC, Albuquerque, New Mexico, USA
MMWR Surveill Summ 52:1-13. 2003
- Prehypertension, diabetes, and cardiovascular disease risk in a population-based sample: the Strong Heart Study
Center for American Indian Health Research, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA
Hypertension 47:410-4. 2006
..Clinical investigation of more aggressive interventions, such as drug treatment for blood pressure control for prehypertensive individuals with impaired fasting glucose, impaired glucose tolerance, or diabetes is warranted...
- Genetic studies of the etiology of type 2 diabetes in Pima Indians: hunting for pieces to a complicated puzzle
Leslie J Baier
Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 4212 N 16th Street, Phoenix, AZ 85016, USA
Diabetes 53:1181-6. 2004
- Prevalence and correlates of Chlamydia infection in Canadian street youth
Susanne A Shields
Division of Community Acquired Infections, Centre for Infectious Disease Prevention and Control, Health Canada, Ottawa, Ontario Canada
J Adolesc Health 34:384-90. 2004
..To determine the prevalence and correlates of Chlamydia trachomatis in Canadian street youth...
- P3 components and adolescent binge drinking in Southwest California Indians
Cindy L Ehlers
Department of Molecular and Integrative Neurosciences, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
Neurotoxicol Teratol 29:153-63. 2007
..Taken together these preliminary studies suggests that adolescent binge drinking may result in a decreases in P3 component latencies and amplitudes perhaps reflecting a loss or delay in the development of inhibitory brain systems...
- On the number of New World founders: a population genetic portrait of the peopling of the Americas
Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA
PLoS Biol 3:e193. 2005
..Analyses of Asian and New World data support a model of a recent founding of the New World by a population of quite small effective size...
- Changing patterns of type 2 diabetes incidence among Pima Indians
Meda E Pavkov
Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 East Indian School Rd, Phoenix, AZ 85014 4972, USA
Diabetes Care 30:1758-63. 2007
..We examined trends in the incidence rate of type 2 diabetes among Pima Indians between 1965 and 2003...
- Physical activity and Native Americans: a review
James D Coble
School of Physical Education, Behavioral Medicine Laboratory, Faculty of Education, University of Victoria, Victoria, British Columbia, Canada
Am J Prev Med 31:36-46. 2006
..Further, the application of psychosocial models to understand physical activity motivations as well as culturally appropriate and validated measurement tools are largely absent in the Native-American physical activity literature...
- Relation of fibrinogen to cardiovascular events is independent of preclinical cardiovascular disease: the Strong Heart Study
Weill Medical College of Cornell University, New York, NY, USA
Am Heart J 145:467-74. 2003
..It is unclear whether fibrinogen predicts cardiovascular events independently of echocardiographic cardiovascular abnormalities and traditional risk factors...
- Fish consumption and other environmental exposures and their associations with serum PCB concentrations among Mohawk women at Akwesasne
Edward F Fitzgerald
Bureau of Environmental and Occupational Epidemiology, New York State Department of Health, 547 River Street, Room 200, Troy, NY 12180 2216, USA
Environ Res 94:160-70. 2004
- Health disparities and toxicant exposure of Akwesasne Mohawk young adults: a partnership approach to research
Lawrence M Schell
Department of Epidemiology, University at Albany, State University of New York, Albany, NY 12222, USA
Environ Health Perspect 113:1826-32. 2005
..Although challenges arose during the design and implementation of the research project, a collaborative approach has benefited the community and facilitated research...
- Adiponectin in a native Canadian population experiencing rapid epidemiological transition
Anthony J G Hanley
Leadership Sinai Centre for Diabetes, Mt Sinai Hospital, Toronto, Ontario, Canada
Diabetes Care 26:3219-25. 2003
- Individual estimates of European genetic admixture associated with lower body-mass index, plasma glucose, and prevalence of type 2 diabetes in Pima Indians
R C Williams
Department of Anthropology, Arizona State University, Box 872402, Tempe, AZ 85287 2402, USA
Am J Hum Genet 66:527-38. 2000
..These data also illustrate the strong genetic components in type 2 diabetes and are consistent with one susceptibility locus common to obesity and diabetes...
- Changes in BMI and weight before and after the development of type 2 diabetes
H C Looker
Diabetes and Arthritis Epidemiology Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona 85014, USA
Diabetes Care 24:1917-22. 2001
..To examine weight changes occurring before and after the diagnosis of diabetes and the association of these changes with treatment and microvascular complications...
- Pentachlorophenol and hydroxylated polychlorinated biphenyl metabolites in umbilical cord plasma of neonates from coastal populations in Québec
Courtney D Sandau
Centre for Analytical and Environmental Chemistry, Department of Chemistry, Carleton University, Ottawa, Ontario, Canada
Environ Health Perspect 110:411-7. 2002
..Further studies are needed to examine the effects of chlorinated phenolic compounds on thyroid hormone status in newborns...
- An autosomal genomic scan for loci linked to prediabetic phenotypes in Pima Indians
R E Pratley
Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85016, USA
J Clin Invest 101:1757-64. 1998
..None of the linkages exceeded a LOD score of 3.6 (a 5% probability of occurring in a genome-wide scan). These findings must, therefore, be considered tentative until extended in this population or replicated in others...
- Genomewide search for genes influencing percent body fat in Pima Indians: suggestive linkage at chromosome 11q21-q22. Pima Diabetes Gene Group
R A Norman
Clinical Diabetes and Nutrition Section, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Phoenix, AZ 85016 5319, USA
Am J Hum Genet 60:166-73. 1997
..Evidence for linkage at 3p24.2-p22 did not change. No association was detected for any marker in the region. Although several genes are known in the 11q21-q22 region, none have been implicated as candidate genes for obesity...
- Founding Amerindian mitochondrial DNA lineages in ancient Maya from Xcaret, Quintana Roo
Departamento de Biologia, Facultad de Ciencias, Universidad Nacional Autonoma de Mexico, Mexico D F 04510, Mexico
Am J Phys Anthropol 116:230-5. 2001
..On the other hand, our results resemble more closely the frequencies of mtDNA lineages found in contemporary Maya from the Yucatán Peninsula and in other Native American contemporary populations of Mesoamerican origin...
- Serious adverse events associated with bacille Calmette-Guérin vaccine in Canada
Shelley L Deeks
Immunization and Respiratory Infections Division, Community Acquired Infections Division, Public Health Agency of Canada, Health Canada, Ottawa, Ontario
Pediatr Infect Dis J 24:538-41. 2005
..Targeted Bacille Calmette-Guérin (BCG) vaccination is offered to neonates in some First Nations and Inuit (FNI) communities in Canada. Serious adverse events associated with BCG vaccine prompted a review to assess causality...
- Alcohol consumption and other maternal risk factors for fetal alcohol syndrome among three distinct samples of women before, during, and after pregnancy: the risk is relative
Philip A May
Center on Alcoholism, Substance Abuse, and Addictions, University of New Mexico, 2650 Yale Boulevard SE, Suite 100, Albuquerque, NM 87106 3202, USA
Am J Med Genet C Semin Med Genet 127:10-20. 2004
..Collecting extensive behavioral information as well as genetic histories will provide the requisite information for making an accurate diagnosis of FAS...
- Enhanced case management to prevent fetal alcohol spectrum disorders in Northern Plains communities
Philip A May
Center on Alcoholism, Substance Abuse and Addictions CASAA, The University of New Mexico, 2650 Yale Blvd, SE Suite 100, Albuquerque, NM 87106, USA
Matern Child Health J 12:747-59. 2008
- Community-based participatory research: an approach to intervention research with a Native American community
Patricia A Holkup
College of Nursing, Montana State University Bozeman, Missoula Campus, Missoula, MT 59812, USA
ANS Adv Nurs Sci 27:162-75. 2004
..In this article, we describe how we managed the challenges we encountered while conducting a CBPR project with a Native American community. We also suggest criteria that will enable evaluation of the project...
- An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians
R L Hanson
Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA
Am J Hum Genet 63:1130-8. 1998
..Sib-pair analyses suggest additional potential diabetes-susceptibility loci on chromosomes 1q and 7q...
- Prenatal exposure of the northern Québec Inuit infants to environmental contaminants
Department of Social and Preventive Medicine, Laval University and Public Health Research Unit, CHUQ Research Center CHUL, Beauport, Quebec, Canada
Environ Health Perspect 109:1291-9. 2001
..Similarly, the weak correlations noted between environmental contaminants and nutrients will facilitate the documentation of possible protective effects afforded by either n3-PUFA or selenium against neurotoxic contaminants...
- Smoking behavior among urban and rural Native American adolescents in California
Jennifer B Unger
University of Southern California School of Medicine, Institute for Health Promotion and Disease Research, Los Angeles, California, USA
Am J Prev Med 25:251-4. 2003
..This study used statewide data from California to examine the smoking behavior and related psychosocial risk factors among Native American adolescents living in urban and rural counties...
- Predominant effect of kidney disease on mortality in Pima Indians with or without type 2 diabetes
Meda E Pavkov
Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014 4972, USA
Kidney Int 68:1267-74. 2005
..We examined the effect of kidney disease (KD) on mortality in nondiabetic and diabetic Pima Indians aged > or = 45 years old...
- Subcutaneous abdominal preadipocyte differentiation in vitro inversely correlates with central obesity
Paska A Permana
Clinical Diabetes and Nutrition Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85016, USA
Am J Physiol Endocrinol Metab 286:E958-62. 2004
..The lower differentiation potential of preadipocytes in the obese subjects might be due, at least partly, to decreased glucocorticoid receptor expression...
- Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: increased expression of inflammation-related genes
Y H Lee
Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA
Diabetologia 48:1776-83. 2005
..The aim of this study was to characterise, in adipocytes from obese people, the most differentially expressed genes that might be relevant to the development of obesity...
- The hepatic nuclear factor-1alpha G319S variant is associated with early-onset type 2 diabetes in Canadian Oji-Cree
R A Hegele
Robarts Research Institute, University of Western Ontario, London, Canada
J Clin Endocrinol Metab 84:1077-82. 1999
..Also, G319S is associated with a distinct form of type 2 diabetes, characterized by onset at an earlier age, lower body mass, and a higher postchallenge plasma glucose...
- The impact of diabetes on cardiovascular risk factors and outcomes in a native Canadian population
Stewart B Harris
Department of Family Medicine, Department of Biostatistics and Epidemiology, The University of Western Ontario, London, Ont, Canada
Diabetes Res Clin Pract 55:165-73. 2002
..This trend is expected to continue unless the high rates of diabetes can be modified...
- Co-morbidity of select anxiety, affective, and psychotic disorders with cannabis dependence in Southwest California Indians
David A Gilder
Moleciular and and Integrative Neurosciences Department, The Scripps Research Institute, La Jolla, CA 92037, USA
J Addict Dis 25:67-79. 2006
..No significant co-morbidity with independent psychiatric disorders was found. In SWC Indians, cannabis dependence may be less etiologically related to psychiatric disorders than in the general population...