proxy

Summary

Summary: A person authorized to decide or act for another person, for example, a person having durable power of attorney.

Top Publications

  1. pmc Proxy evaluation of health-related quality of life: a conceptual framework for understanding multiple proxy perspectives
    A Simon Pickard
    College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA
    Med Care 43:493-9. 2005
  2. pmc Factors influencing agreement between child self-report and parent proxy-reports on the Pediatric Quality of Life Inventory 4.0 (PedsQL) generic core scales
    Joanne Cremeens
    Division of Behavioral Medicine, St Jude Children s Research Hospital, Memphis, TN, USA
    Health Qual Life Outcomes 4:58. 2006
  3. pmc Measuring adolescents' HRQoL via self reports and parent proxy reports: an evaluation of the psychometric properties of both versions of the KINDL-R instrument
    Michael Erhart
    Child Public Health, Department of Psychosomatics in Children and Adolescents, University Medical Center Hamburg Eppendorf, Martinistr, 52, D 20246 Hamburg, Germany
    Health Qual Life Outcomes 7:77. 2009
  4. pmc Studying Chinese suicide with proxy-based data: reliability and validity of the methodology and instruments in China
    Jie Zhang
    Department of Sociology, State University of New York College at Buffalo, 1300 Elmwood Avenue, Buffalo, New York 14222, USA
    J Nerv Ment Dis 191:450-7. 2003
  5. ncbi Health of children with chronic arthritis: relationship of different measures and the quality of parent proxy reporting
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229 3039, USA
    Arthritis Rheum 51:763-73. 2004
  6. pmc Health-related quality of life measurement in pediatric clinical practice: an appraisal and precept for future research and application
    James W Varni
    Department of Pediatrics, College of Medicine, Texas A and M University, 3137 TAMU, College Station, TX 77843 3137, USA
    Health Qual Life Outcomes 3:34. 2005
  7. pmc Development of six PROMIS pediatrics proxy-report item banks
    Debra E Irwin
    Department of Epidemiology, University of North Carolina at Chapel Hill, NC 27599, USA
    Health Qual Life Outcomes 10:22. 2012
  8. ncbi Measurement equivalence across child self-reports and parent-proxy reports in the Chinese version of the pediatric quality of life inventory version 4.0
    Chung Ying Lin
    Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    Child Psychiatry Hum Dev 44:583-90. 2013
  9. pmc Fatigue in children: reliability and validity of the Dutch PedsQL™ Multidimensional Fatigue Scale
    M Suzanne Gordijn
    Department of Pediatrics, VU University Medical Center Amsterdam, PK 4X 033, P O Box 7057, 1007 MB, Amsterdam, The Netherlands
    Qual Life Res 20:1103-8. 2011
  10. ncbi EQ-5D in patients with dementia: an investigation of inter-rater agreement
    W Coucill
    Health Economics Facility, University of Birmingham, England, UK
    Med Care 39:760-71. 2001

Detail Information

Publications252 found, 100 shown here

  1. pmc Proxy evaluation of health-related quality of life: a conceptual framework for understanding multiple proxy perspectives
    A Simon Pickard
    College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA
    Med Care 43:493-9. 2005
    b>Proxy assessment of health-related quality of life (HRQL) may be sought to substitute for, or to complement, patient self-assessment...
  2. pmc Factors influencing agreement between child self-report and parent proxy-reports on the Pediatric Quality of Life Inventory 4.0 (PedsQL) generic core scales
    Joanne Cremeens
    Division of Behavioral Medicine, St Jude Children s Research Hospital, Memphis, TN, USA
    Health Qual Life Outcomes 4:58. 2006
    ..unable or unwilling to respond for themselves, measurement of quality of life (QOL) is often obtained by parent proxy-report...
  3. pmc Measuring adolescents' HRQoL via self reports and parent proxy reports: an evaluation of the psychometric properties of both versions of the KINDL-R instrument
    Michael Erhart
    Child Public Health, Department of Psychosomatics in Children and Adolescents, University Medical Center Hamburg Eppendorf, Martinistr, 52, D 20246 Hamburg, Germany
    Health Qual Life Outcomes 7:77. 2009
    ..are available to assess children's health-related quality of life (HRQoL) based on self reports as well as proxy reports from parents...
  4. pmc Studying Chinese suicide with proxy-based data: reliability and validity of the methodology and instruments in China
    Jie Zhang
    Department of Sociology, State University of New York College at Buffalo, 1300 Elmwood Avenue, Buffalo, New York 14222, USA
    J Nerv Ment Dis 191:450-7. 2003
    ..All the tested instruments were shown to be reliable, and proxy respondents were generally good judges of targets' suicidal intention, social support, depression, life events, ..
  5. ncbi Health of children with chronic arthritis: relationship of different measures and the quality of parent proxy reporting
    Hermine I Brunner
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229 3039, USA
    Arthritis Rheum 51:763-73. 2004
    ..To evaluate whether HRQOL scores vary as a function of disability status beyond chance. To assess the quality of the parent proxy report for HRQOL as compared with disability, pain, and well-being.
  6. pmc Health-related quality of life measurement in pediatric clinical practice: an appraisal and precept for future research and application
    James W Varni
    Department of Pediatrics, College of Medicine, Texas A and M University, 3137 TAMU, College Station, TX 77843 3137, USA
    Health Qual Life Outcomes 3:34. 2005
    ....
  7. pmc Development of six PROMIS pediatrics proxy-report item banks
    Debra E Irwin
    Department of Epidemiology, University of North Carolina at Chapel Hill, NC 27599, USA
    Health Qual Life Outcomes 10:22. 2012
    ..exist when the child is too young, cognitively impaired, or too ill to complete a PRO instrument and a proxy-report is needed...
  8. ncbi Measurement equivalence across child self-reports and parent-proxy reports in the Chinese version of the pediatric quality of life inventory version 4.0
    Chung Ying Lin
    Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    Child Psychiatry Hum Dev 44:583-90. 2013
    ..child- and parent-reported Chinese PedsQL was examined, and the latent means between child self-reports and parent-proxy reports were compared...
  9. pmc Fatigue in children: reliability and validity of the Dutch PedsQL™ Multidimensional Fatigue Scale
    M Suzanne Gordijn
    Department of Pediatrics, VU University Medical Center Amsterdam, PK 4X 033, P O Box 7057, 1007 MB, Amsterdam, The Netherlands
    Qual Life Res 20:1103-8. 2011
    ..The aim of the study is to report on the feasibility, reliability, validity, and the norm-references of the Dutch version of the PedsQL™ Multidimensional Fatigue Scale...
  10. ncbi EQ-5D in patients with dementia: an investigation of inter-rater agreement
    W Coucill
    Health Economics Facility, University of Birmingham, England, UK
    Med Care 39:760-71. 2001
    ..There are difficulties in obtaining health-related quality of life (HRQL) data from patients with dementia due to variation in their cognitive ability, degree of insight and capacity to make judgments. The use of proxies is one solution...
  11. ncbi Economic valuation of informal care: lessons from the application of the opportunity costs and proxy good methods
    Bernard van den Berg
    Centre for Health Economics Research and Evaluation, Faculty of Business, University of Technology, Sydney
    Soc Sci Med 62:835-45. 2006
    This paper reports the results of the application of the opportunity costs and proxy good methods to determine a monetary value of informal care...
  12. pmc Quality of Life as reported by school children and their parents: a cross-sectional survey
    Thomas Jozefiak
    The Norwegian University of Technology and Science NTNU, Regional Centre of Child and Adolescent Mental Health MTFS N 7489, Dept, of Child and Adolescent Psychiatry St, Olav Hospital, 7000 Trondheim, Norway
    Health Qual Life Outcomes 6:34. 2008
    Comprehensive evidence exists regarding the discrepancy between children's reports and parents' by proxy reports on emotional and behavioural problems...
  13. ncbi The Prospective and Retrospective Memory Questionnaire (PRMQ): latent structure, normative data and discrepancy analysis for proxy-ratings
    John R Crawford
    School of Psychology, King s College, University of Aberdeen, Aberdeen AB24 2UB, UK
    Br J Clin Psychol 45:83-104. 2006
    To evaluate the proxy-rating version of the Prospective and Retrospective Memory Questionnaire (PRMQ) and provide norms and methods for score interpretation.
  14. ncbi Validation of the European proxy KIDSCREEN-52 pilot test health-related quality of life questionnaire: first results
    Stephane Robitail
    Perceived Health Research Unit, School of Medicine, Marseille, France
    J Adolesc Health 39:596.e1-10. 2006
    ..b>Proxy measures HRQoL should be a useful and practical alternative to assess children's HRQoL...
  15. ncbi Estimating preference-based single index measures for dementia using DEMQOL and DEMQOL-Proxy
    Donna Rowen
    Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Regent Court, Sheffield, UK
    Value Health 15:346-56. 2012
    ..this gap by estimating two preference-based single index measures: the DEMQOL-U from the self-report DEMQOL (mild-to-moderate dementia severity) and the DEMQOL-Proxy-U from the carer-report DEMQOL-Proxy (all levels of dementia severity).
  16. pmc Determinants of agreement between self-reported and parent-assessed quality of life for children in Germany-results of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS)
    Ute Ellert
    Department of Health Reporting, Robert Koch Institute, Seestr, 10, 13353 Berlin, Germany
    Health Qual Life Outcomes 9:102. 2011
    The aim of this study is to quantify the level of agreement between self-reporting and proxy-assessment of children's health-related quality of life using KINDL-R in a large population based study in Germany and to identify factors which ..
  17. pmc Proxy assessment of health-related quality of life in african american and white respondents with prostate cancer: perspective matters
    A Simon Pickard
    Department of Pharmacy Practice and Pharmacy Administration, Center for Pharmacoeconomic Research, College of Pharmacy, University of Illinois at Chicago, Chicago, USA
    Med Care 47:176-83. 2009
    An emerging issue in the proxy literature is whether specifying different proxy viewpoints contributes to different health-related quality of life (HRQL) assessments, and if so, how might each perspective be informative in medical ..
  18. pmc Validation of a parent-proxy, obesity-specific quality-of-life measure: sizing them up
    Avani C Modi
    Department of Pediatrics, Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Obesity (Silver Spring) 16:2624-33. 2008
    The aims of the present study were to develop and validate a new obesity-specific, parent-proxy measure of health-related quality of life (HRQOL), Sizing Them Up. Participants included 220 obese youth (M(age) = 11...
  19. ncbi Reliability of proxy respondents for patients with stroke: a systematic review
    Colin Oczkowski
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    J Stroke Cerebrovasc Dis 19:410-6. 2010
    b>Proxy respondents are an important aspect of stroke medicine and research. We performed a systematic review of studies evaluating the reliability of proxy respondents for stroke patients...
  20. ncbi Children proxies' quality-of-life agreement depended on the country using the European KIDSCREEN-52 questionnaire
    Stephane Robitail
    Perceived Health Research Unit, School of Medicine, Marseille, France
    J Clin Epidemiol 60:469-78. 2007
    ....
  21. ncbi Validation of the human activity profile in stroke: a comparison of observed, proxy and self-reported scores
    Luci Fuscaldi Teixeira-Salmela
    Department of Physical Therapy, Federal University of Minas Gerais, 3127 010 Belo Horizonte, Minas Gerais, Brazil
    Disabil Rehabil 29:1518-24. 2007
    ..of the Human Activity Profile (HAP) with stroke and healthy control individuals, when reported by the subject or a proxy and compared to observed performance, used as gold standard; factors related to discrepancies; as well as to ..
  22. ncbi A case of obsessive-compulsive disorder by proxy
    Menon Vikas
    Department of Psychiatry, JIPMER, Puducherry 605006, India
    Gen Hosp Psychiatry 33:303.e5-6. 2011
    ..text revision). Washington, DC: American Psychiatric Association; 2000). In this report, we describe an interesting case of a 58-year-old lady who substituted her husband for her to perform the compulsive behaviors...
  23. ncbi Two perspectives of proxy reporting of health-related quality of life using the Euroqol-5D, an investigation of agreement
    Steven McPhail
    School of Health and Rehabilitation Sciences, The University of Queensland, Queensland, Australia
    Med Care 46:1140-8. 2008
    b>Proxy-reporting has been proposed as an alternative to self-report of health-related quality of life (HRQoL) for patients with poor cognition...
  24. ncbi Proxy and surrogate consent in geriatric neuropsychiatric research: update and recommendations
    Scott Y H Kim
    Department of Psychiatry and the Program in Clinical Ethics, University of Rochester Medical Center, Rochester, NY, USA
    Am J Psychiatry 161:797-806. 2004
    ..The authors provide an updated discussion, critique, and recommendations regarding the need for clear legal and regulatory policy on this issue...
  25. ncbi Evaluation of proxy responses to the Stroke Impact Scale
    Pamela W Duncan
    Brooks Center for Rehabilitation Studies, University of Florida, and Rehabilitation Outcomes Research Center, North Florida South Georgia Department of Veteran Affairs, Gainesville, Fla 32610 0185, USA
    Stroke 33:2593-9. 2002
    The purposes of this study were to compare proxy-patient responses on each domain of the Stroke Impact Scale (SIS) and the SIS-16, estimate the bias, and evaluate the validity of proxy scores.
  26. ncbi How valid are family proxy assessments of stroke patients' health-related quality of life?
    Linda S Williams
    Health Services Research and Development Service, Roudebush VAMC, 1481 W 10th St, 11 H, Indianapolis, Indiana 46202, USA
    Stroke 37:2081-5. 2006
    b>Proxy respondents are often needed to report outcomes in stroke survivors, but they typically systematically rate impairments worse than patients themselves...
  27. ncbi Quality of life in children with chronic kidney disease (with child and parent assessments)
    Necla Buyan
    Department of Pediatric Nephrology, Gazi University, School of Medicine, Besevler, Ankara, Turkey
    Pediatr Nephrol 25:1487-96. 2010
    ..DP), renal transplant recipients (TR), and age-matched healthy controls and to compare child-self and parent-proxy scores...
  28. ncbi Validation of a parent-proxy quality of life questionnaire for paediatric chronic cough (PC-QOL)
    Peter A Newcombe
    School of Social Work and Applied Human Sciences School of Psychology, The University of Queensland, 11 Salisbury Road, Ipswich, Queensland 4305, Australia
    Thorax 65:819-23. 2010
    ..Currently there is no fully validated cough-specific QOL measure for paediatrics. The objective of this study was to validate a cough-specific QOL questionnaire for paediatric use...
  29. pmc Surrogate consent for dementia research: a national survey of older Americans
    S Y H Kim
    Bioethics Program, University of Michigan, Ann Arbor, MI 48109, USA
    Neurology 72:149-55. 2009
    ..Because AD impairs decisional capacity, informed consent often must come from surrogates, usually close family members. But policies for surrogate consent for research remain unsettled after decades of debate...
  30. ncbi Children's physical activity: using accelerometers to validate a parent proxy record
    Julie M Bender
    Transtria, LLC, St Louis, MO 63139, USA
    Med Sci Sports Exerc 37:1409-13. 2005
    The purpose of this study was to validate a parent proxy record of children's physical activity with CSA Model 7164 accelerometers.
  31. ncbi Do mothers and fathers hold similar views about their child's arthritis?
    Kathleen Mulligan
    University College London, London, UK
    Arthritis Rheum 61:1712-8. 2009
    Evaluations of the well-being of children with juvenile idiopathic arthritis (JIA) typically rely on parents as proxy respondents...
  32. ncbi Correspondence between proxy and self-reports on smoking in a full family study
    Zeena Harakeh
    Institute of Family and Child Care Studies, Radboud University Nijmegen, P O Box 9104, 6500 HE Nijmegen, The Netherlands
    Drug Alcohol Depend 84:40-7. 2006
    The present study investigated the reliability of proxy reports obtained from family members with self-reports on adolescent and parental lifetime and current smoking status.
  33. pmc The PedsQL as a patient-reported outcome in children and adolescents with fibromyalgia: an analysis of OMERACT domains
    James W Varni
    Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A and M University, College Station, TX 77843 3137, USA
    Health Qual Life Outcomes 5:9. 2007
    ..The focus of these deliberations was exclusively on adult patients, and to our knowledge, these domains have not been previously tested within a multidimensional framework in children and adolescents with fibromyalgia...
  34. pmc Validation of a questionnaire for assessing fecal impaction in the elderly: impact of cognitive impairment, and using a proxy
    Marta Barceló
    Functional GI DiseasesUnit, Division of DigestiveDiseases, Hospital Clinico San Carlos, Departament of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos IdISSC, Madrid, Spain
    BMC Geriatr 13:24. 2013
    ..Our aim is to validate a questionnaire for identifying fecal impaction in the elderly and to assess the impact of cognitive impairment and the aid of a proxy on its reliability.
  35. pmc The proxy problem anatomized: child-parent disagreement in health related quality of life reports of chronically ill adolescents
    Jane N T Sattoe
    Rotterdam University, Expertise Centre Transitions of Care, 3001 HA Rotterdam, The Netherlands
    Health Qual Life Outcomes 10:10. 2012
    Discrepancy between self-reports and parent-proxy reports of adolescent health-related quality of life (HRQoL) has been repeatedly acknowledged in the literature as the proxy problem...
  36. ncbi Participant-proxy agreement on objective and subjective aspects of societal participation following traumatic brain injury
    Tessa Hart
    Moss Rehabilitation Research Institute, Elkins Park, Pennsylvania, USA
    J Head Trauma Rehabil 25:339-48. 2010
    ....
  37. pmc Alcohol and premature death in Estonian men: a study of forensic autopsies using novel biomarkers and proxy informants
    Inge Ringmets
    Department of Public Health, University of Tartu, Ravila 19, 50411 Tartu, Estonia
    BMC Public Health 12:146. 2012
    ..We describe the design and initial findings of a study aimed at investigating the association of alcohol with mortality in a large series of forensic autopsies of working-age men in Estonia...
  38. ncbi The validity of proxy-based data in suicide research: a study of patients 50 years of age and older who attempted suicide. II. Life events, social support and suicidal behavior
    K R Conner
    Center for the Study and Prevention of Suicide, University of Rochester Medical Center, 3300 Crittenden Boulevard, Rochester, NY 14642, USA
    Acta Psychiatr Scand 104:452-7. 2001
    OBJECTIVE: To investigate the validity of proxy respondent reports of stressful life events, social support and suicidal behavior among individuals who attempted suicide...
  39. ncbi Poor-to-moderate agreement between self and proxy interviews of mobile phone use
    Hans Peter Hutter
    Institute of Environmental Health, Center for Public Health, Medical University Vienna, Vienna, Austria
    Bioelectromagnetics 33:561-7. 2012
    ..Under these circumstances, proxy interviews are often conducted; however, the veridicality of information about mobile phone use gained by proxy ..
  40. pmc Impaired health-related quality of life in children and adolescents with chronic conditions: a comparative analysis of 10 disease clusters and 33 disease categories/severities utilizing the PedsQL 4.0 Generic Core Scales
    James W Varni
    Department of Pediatrics, College of Medicine, Texas A and M University, College Station, TX 77843 3137, USA
    Health Qual Life Outcomes 5:43. 2007
    ..Comparisons were also benchmarked with healthy children data...
  41. ncbi Discrepancy between self- and proxy-rated pain in Alzheimer's disease: results from the Danish Alzheimer Intervention Study
    Christina Jensen-Dahm
    Memory Disorders Research Group, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    J Am Geriatr Soc 60:1274-8. 2012
    To investigate the prevalence of self- and proxy-reported pain in a cohort with Alzheimer's disease (AD) and to identify characteristics of individuals with AD reporting pain.
  42. ncbi Interpreting parental proxy reports of (health-related) quality of life for children with unilateral cochlear implants
    Tracey H Sach
    School of Community Health Sciences, 13th Floor Tower Building, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Int J Pediatr Otorhinolaryngol 71:435-45. 2007
    ..To examine what factors are associated with EuroQol EQ-5D scores in children after unilateral cochlear implantation and to explore parental conceptualisations of health-related quality of life (HRQL) and quality of life (QoL)...
  43. ncbi Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: the Pediatric Rheumatology International Trials Organization multinational quality of life cohort study
    Sheila Oliveira
    IRCCS G Gaslini, Pediatria II, Reumatologia, Pediatric Rheumatology International Trials Organization, Genoa, Italy
    Arthritis Rheum 57:35-43. 2007
    To investigate the proxy-reported health-related quality of life (HRQOL) and its determinants in patients with juvenile idiopathic arthritis (JIA).
  44. pmc Combining direct and proxy assessments to reduce attrition bias in a longitudinal study
    Qiong Wu
    Harvard Center for Population and Development Studies, Harvard University, Cambridge, MA, USA
    Alzheimer Dis Assoc Disord 27:207-12. 2013
    ..Thereafter, proxy informants, typically spouses, assess the subject's memory and cognitive function using standardized instruments...
  45. ncbi Assessing quality of life of older people with dementia: a comparison of quantitative self-report and proxy accounts
    Wendy Moyle
    Research Centre for Clinical and Community Practice Innovation, Griffith Health Institute, Griffith University, Brisbane, Queensland, Australia
    J Adv Nurs 68:2237-46. 2012
    ..This article reports on a study of quality of life of older people with dementia, as assessed by the person with dementia, family carer and care staff...
  46. ncbi Agreement between pediatric brain tumor patients and parent proxy reports regarding the Pediatric Functional Assessment of Cancer Therapy-Childhood Brain Tumor Survivors questionnaire, version 2
    Hee Jung Yoo
    Department of Neurosurgery, Asan Medical Center, University of Ulsan, College of Medicine, and Department of Pediatric Neurosurgery, Severance Children s Hospital, Seoul, Korea
    Cancer 116:3674-82. 2010
    This study investigated the agreement between self-reports from pediatric brain tumor patients and proxy reports from their parents regarding the patients' quality of life (QOL), as assessed using a brain tumor-specific QOL assessment ..
  47. ncbi Proxy reporting of quality of life using the EQ-5D
    Hani Tamim
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    Med Care 40:1186-95. 2002
    ..The economic evaluation of health interventions for older people is complicated by the difficulty in obtaining self-reports of quality of life from persons with cognitive impairments, physical impairments, or both...
  48. pmc Proxy consent: moral authority misconceived
    A Wrigley
    Centre for Professional Ethics PEAK, University of Keele, Keele, Staffordshire, ST5 5BG, UK
    J Med Ethics 33:527-31. 2007
    The Mental Capacity Act 2005 has provided unified scope in the British medical system for proxy consent with regard to medical decisions, in the form of a lasting power of attorney...
  49. ncbi Minimally important change in a Parent-Proxy Quality-of-Life questionnaire for pediatric chronic cough
    Peter A Newcombe
    School of Social Work and Applied Human Sciences, The University of Queensland, and Queensland Children s Respiratory Centre and Queensland Children s Medical Research Institute, Royal Children s Hospital, Brisbane, QLD 4072, Australia
    Chest 139:576-80. 2011
    ..Its validity has been demonstrated. This study sought to determine the minimally important difference (MID) for the PC-QOL completed by parents of young children with chronic cough...
  50. ncbi Parent proxy-reported quality of life for children with cerebral palsy: is it related to parental psychosocial distress?
    E Davis
    Jack Brockhoff Child Health and Wellbeing Program, Melbourne School of Population Health, University of Melbourne Centre for Youth Mental Health, University of Melbourne, Melbourne, Vic, Australia
    Child Care Health Dev 38:553-60. 2012
    Parent-proxy reports of quality of life (QOL) are often used to guide decisions about children with cerebral palsy (CP), although little is known about the factors that influence parent-proxy reports...
  51. pmc Utilization of the propensity score method: an exploratory comparison of proxy-completed to self-completed responses in the Medicare Health Outcomes Survey
    Beth Hartman Ellis
    Surveys, Research and Analysis Health Services Advisory Group, Inc, Phoenix, AZ 85020 United States of America
    Health Qual Life Outcomes 1:47. 2003
    This research examined the use of the propensity score method to compare proxy-completed responses to self-completed responses in the first three baseline cohorts of the Medicare Health Outcomes Survey, administered in 1998, 1999, and ..
  52. pmc Beers criteria as a proxy for inappropriate prescribing of other medications among older adults
    Brian C Lund
    Center for Comprehensive Access and Delivery Research and Evaluation, Veterans Affairs Iowa City Health Care System, Iowa City, IA, USA
    Ann Pharmacother 45:1363-70. 2011
    ..The Beers criteria are a compilation of medications deemed potentially inappropriate for older adults, widely used as a prescribing quality indicator...
  53. ncbi Assessing agreement between terminally ill cancer patients' reports of their quality of life and family caregiver and palliative care physician proxy ratings
    Jennifer M Jones
    Department of Psychosocial Oncology and Palliative Care, Princess Margaret Hospital, Toronto, Ontario, Canada
    J Pain Symptom Manage 42:354-65. 2011
    b>Proxy ratings, if valid, may provide an alternative approach to evaluating patient quality of life (QoL) at the end of life.
  54. pmc Agreement between proxy and adolescent assessment of disability, pain, and well-being in juvenile idiopathic arthritis
    Sham D Lal
    Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, United Kingdom
    J Pediatr 158:307-12. 2011
    Adolescents with juvenile idiopathic arthritis have demonstrated substantial disagreement with their proxy's assessment of their disability, pain, and well-being...
  55. ncbi The change in child self-assessed and parent proxy-assessed Health Related Quality of Life (HRQL) in early adolescence (age 10-12)
    Camilla B Laaksonen
    Department of Nursing Science, University of Turku, Finland
    Scand J Public Health 38:9-16. 2010
    To examine the development of self-assessed and parent proxy-assessed health related quality of life (HRQL) in pre-adolescent schoolchildren.
  56. ncbi Religiousness and mood in the last week of life: an explorative approach based on after-death proxy interviews
    Arjan W Braam
    VU University Medical Centre, EMGO Institute for Health and Care Research, Department of Epidemiology and Biostatistics Longitudinal Aging Study Amsterdam, Amsterdam, The Netherlands
    J Palliat Med 14:31-7. 2011
    ..For the current study, after-death interviews with proxy respondents of deceased sample members of the Longitudinal Aging Study Amsterdam provided information on ..
  57. ncbi Parent-proxy ratings of pain before and after botulinum toxin type A treatment for children with spasticity and cerebral palsy
    Patrick F Rivard
    Gillette Children s Specialty Healthcare, Neurodevelopment Pediatrics, University of Minnesota, Minneapolis, MN, USA
    Clin J Pain 25:413-7. 2009
    ..To test the hypothesis that pain would be reduced after botulinum toxin type A (Btx/A) treatment for children with cerebral palsy (CP)...
  58. ncbi [Validity of occupational histories from proxy respondents]
    R Cordeiro
    Departamento de Saude Publica, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brasil
    Rev Saude Publica 34:522-8. 2000
    Occupational studies often use data obtained from proxy respondents. However, few investigations have been conducted on the validity of occupational data provided by workers' surrogates...
  59. ncbi Analysis of patient and proxy ratings on the Dysexecutive Questionnaire: an application of Rasch analysis
    R C K Chan
    Neuropsychology and Applied Cognitive Neuroscience Laboratory, Institute of Psychology, Chinese Academy of Sciences, Beijing, China
    J Neurol Neurosurg Psychiatry 79:86-8. 2008
    We provide an alternate method of analysing self-report and proxy-report data on subjective complaints of dysexecutive symptoms among a group of patients with traumatic brain injury.
  60. ncbi Adult smoking as a proxy for environmental tobacco smoke exposure among children - comparing the impact of the level of information in Estonia, Finland and Latvia
    Kristiina Patja
    National Institute for Health and Welfare, Finland
    Prev Med 49:240-4. 2009
    ..This study assesses whether estimating children's exposure from information on adult smoking and exposure to ETS makes international comparisons more reliable...
  61. pmc Measuring health-related quality of life in population-based studies of coronary heart disease: comparing six generic indexes and a disease-specific proxy score
    Noelle C Garster
    Department of Population Health Sciences, University of Wisconsin Madison, WARF Office Building Room 707, 610 Walnut Street, Madison, WI 53726, USA
    Qual Life Res 18:1239-47. 2009
    To compare HRQoL differences with CHD in generic indexes and a proxy CVD-specific score in a nationally representative sample of U.S. adults.
  62. ncbi Adolescent chronic pain-related functioning: concordance and discordance of mother-proxy and self-report ratings
    Lindsey L Cohen
    Department of Psychology, Georgia State University, USA
    Eur J Pain 14:882-6. 2010
    ..In this study, we aimed to examine concordance and discordance in adolescents' self-report and mothers' proxy-report of adolescents' chronic pain-related functioning...
  63. ncbi Illusion of control by proxy: placing one's fate in the hands of another
    Michael J A Wohl
    Department of Psychology, Carleton University, Ottawa, Ontario, Canada
    Br J Soc Psychol 48:183-200. 2009
    ..e. the illusion of control by proxy. In Experiment 1, participants were told that they would receive a scratch-and-win lottery ticket as a gratuity ..
  64. pmc Proxy and self-report agreement on the Stroke and Aphasia Quality of Life Scale-39
    Katerina Hilari
    Department of Language and Communication Science, Institute of Health Sciences, City University, Northampton Square, London EC1V 0HB, UK
    J Neurol Neurosurg Psychiatry 78:1072-5. 2007
    ..People with severe aphasia after stroke may be unable to self-report on such measures, necessitating the use of proxy respondents...
  65. ncbi [The influence of proxy respondents on health perception among older adults: a study based on the Brazilian National Household Survey (1998, 2003) and the cohort study in Bambuí, Minas Gerais State, Brazil]
    Maria Fernanda Lima-Costa
    Núcleo de Estudos em Saúde Pública e Envelhecimento, Fundação Oswaldo Cruz Universidade Federal de Minas Gerais, Belo Horizonte, Brasil
    Cad Saude Publica 23:1893-902. 2007
    This study was developed to examine whether the use of a proxy respondent influences the distribution and factors associated with health perception among older adults, as well as the mortality relative risk...
  66. ncbi Proxy completion of EQ-5D in patients with dementia
    S Bryan
    Health Economics Facility, Health Services Management Centre, University of Birmingham, Birmingham, UK
    Qual Life Res 14:107-18. 2005
    ..whether construct validity is greater for 'family caregivers' or 'clinicians' as two alternative sources of proxy information for patients with a diagnosis of dementia...
  67. ncbi Comparison of self-reports and parent proxy-reports of function and quality of life of children with below-the-elbow deficiency
    Lindsey C Sheffler
    Department of Orthopaedic Surgery, University of California, Davis, School of Medicine, Sacramento, CA 95817, USA
    J Bone Joint Surg Am 91:2852-9. 2009
    The agreement between children's self-reports and parent proxy-reports has not been established for function and quality-of-life measures for children with musculoskeletal diagnoses, including unilateral congenital below-the-elbow ..
  68. ncbi Proxy informed consent in pediatric research: a review
    M Cuttini
    Unit of Epidemiology, Burlo Garofolo Maternal and Child Health Institute, Trieste, Italy
    Early Hum Dev 60:89-100. 2000
    This paper is aimed at discussing the issue of proxy consent for medical research with children carried out in the context of developed countries...
  69. ncbi Is length of stay in hospital a stable proxy for injury severity?
    C Cryer
    Injury Prevention Research Unit, University of Otago, Dunedin, New Zealand
    Inj Prev 16:254-60. 2010
    Is length of stay (LoS) in hospital a stable proxy for severity of injury when monitoring time trends in serious injury incidence?
  70. ncbi Agreement between Internet-based self- and proxy-reported health care resource utilization and administrative health care claims
    Liisa Palmer
    Thomson Reuters, Outcomes Research, Washington, DC, USA
    Value Health 15:458-65. 2012
    ..common, little is known about agreement between administrative claims data and Internet-based survey self- and proxy-reported health care resource utilization (HCRU) data...
  71. pmc Preservation of the capacity to appoint a proxy decision maker: implications for dementia research
    Scott Y H Kim
    Center Bioethics and Social Sciences in Medicine, and Department of Psychiatry, University of Michigan, 300 N Ingalls St, 7C27, Ann Arbor, MI 48109, USA
    Arch Gen Psychiatry 68:214-20. 2011
    ..If individuals incapable of consenting to research studies were able to appoint a research proxy, it would allow for an appointed surrogate (rather than a de facto surrogate) to represent the subject.
  72. ncbi Communication between older people and their health care agents: results of an intervention
    Irene A Gutheil
    Ravazzin Center for Social Work Research in Aging, Graduate School of Social Service, Fordham University, Tarrytown, NY 10591, USA
    Health Soc Work 30:107-16. 2005
    ..participants, there was a statistically significant difference between groups on knowledge of the health care proxy form and the roles and responsibilities of the agent...
  73. ncbi "What the patient would have decided": a fundamental problem with the substituted judgment standard
    Linus Broström
    Department of Medical Ethics, Lund University, BMC C13, Lund, 221 84, Sweden
    Med Health Care Philos 10:265-78. 2007
    ..The article discusses this problem of underdetermined decision conditions...
  74. pmc Quality of life in children newly diagnosed with cancer and their mothers
    Christine Eiser
    CR UK Child and Family Research Group, Department of Psychology, University of Sheffield, S10 2TP, UK
    Health Qual Life Outcomes 3:29. 2005
    ....
  75. ncbi Validity of parent ratings as proxy measures of pain in children with cognitive impairment
    Terri Voepel-Lewis
    University of Michigan Medical Center, Ann Arbor, 48109, USA
    Pain Manag Nurs 6:168-74. 2005
    Parent-assigned pain scores have been used as proxy measures of pain for children, such as those with cognitive impairment (CI), who cannot self-report...
  76. ncbi Preferences in end-of-life care of older persons: after-death interviews with proxy respondents
    Marianne Klinkenberg
    Department of Social Medicine, Institute for Research in Extramural Medicine, VU University Medical Centre, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    Soc Sci Med 59:2467-77. 2004
    ..Interviews were held with 270 proxy respondents of 342 deceased persons (age range 59-91) in the Netherlands, The deceased were respondents to the ..
  77. pmc Knowledge of the legislation governing proxy consent to treatment and research
    G Bravo
    Department of Community Health Sciences, University of Sherbrooke, Quebec, Canada
    J Med Ethics 29:44-50. 2003
    ..To assess the knowledge of four groups of individuals regarding who is legally authorised to consent to health care or research involving older patients...
  78. ncbi Self- and proxy-report agreement on the Stroke Impact Scale
    Francisco Javier Carod-Artal
    Neurology Department, Sarah Hospital, Brasilia DF, Brazil
    Stroke 40:3308-14. 2009
    The purpose of this study was to examine proxy-patient agreement on the domains of the Stroke Impact Scale (SIS), as per the proxy-proxy perspective.
  79. ncbi Empirical assessment of a research advance directive for persons with dementia and their proxies
    Carol B Stocking
    Section of Geriatrics, Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    J Am Geriatr Soc 55:1609-12. 2007
    ..To evaluate a research advance directive for persons with established dementia diagnoses and their family caregivers or proxies...
  80. ncbi Research advance directives: protection or obstacle?
    Palaniappan Muthappan
    Department of Clinical Bioethics, NIH, Bldg 10, Rm 1C118, Bethesda, MD 20892, USA
    Am J Psychiatry 162:2389-91. 2005
    ..This study assessed how many adults completed a research advance directive and the preferences indicated on the completed forms...
  81. pmc How do proxy responses and proxy-assisted responses differ from what Medicare beneficiaries might have reported about their health care?
    Marc N Elliott
    RAND Corporation, 1776 Main Street, Santa Monica, CA 90407 2138, USA
    Health Serv Res 43:833-48. 2008
    Assess proxy respondent effects on health care evaluations by Medicare beneficiaries.
  82. ncbi Functional abilities and continence: the use of proxy respondents in research involving older people
    C Shaw
    Centre for Health Services Research, University of Newcastle upon Tyne, UK
    Qual Life Res 9:1117-26. 2000
    As the use of proxy respondents is sometimes necessary in research involving older or disabled people it is important to assess the impact of this on research results...
  83. ncbi Caregivers' judgments of the functional abilities of the Alzheimer's disease patient: a comparison of proxy reports and objective measures
    D A Loewenstein
    Center for Adult Development and Aging and the Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, Florida, USA
    J Gerontol B Psychol Sci Soc Sci 56:P78-84. 2001
    ..Although ratings of functional disability by family or other proxy informants are widely used by clinicians, there have been concerns and empirical evidence that potential reporter ..
  84. ncbi Advance care planning by proxy for residents of long-term care facilities who lack decision-making capacity
    Ladislav Volicer
    Geriatric Research, Education and Clinical Center, Dementia Study Unit, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, Massachusetts, USA
    J Am Geriatr Soc 50:761-7. 2002
    ..whether long-term care facilities should implement policies and procedures to support advance care planning by proxy for residents who lack decision-making capacity...
  85. ncbi Measuring quality of life in children referred for psychiatric problems: psychometric properties of the PedsQL 4.0 generic core scales
    D Bastiaansen
    Department of Child and Adolescent Psychiatry, Erasmus MC Sophia, Rotterdam, The Netherlands
    Qual Life Res 13:489-95. 2004
    ..0) generic core scales and assess its usefulness in measuring quality of life (QoL) in a child psychiatric population...
  86. pmc Advance directives and outcomes of surrogate decision making before death
    Maria J Silveira
    Veterans Affairs Center for Clinical Management Research, and Division of General Medicine, University of Michigan, Ann Arbor, USA
    N Engl J Med 362:1211-8. 2010
    ..Recent discussions about health care reform have raised questions regarding the value of advance directives...
  87. ncbi Why doesn't a family member of a person with advanced dementia use a substituted judgment when making a decision for that person?
    Karen B Hirschman
    School of Nursing, Division of Biobehavioral and Health Sciences, Institute on Aging, University of Pennsylvania, 3615 Chestnut Street, Philadelphia, PA 19104, USA
    Am J Geriatr Psychiatry 14:659-67. 2006
    ..The objective of this study was to identify what standard of decision making a family member uses when making medical decisions for their relative with advanced dementia...
  88. ncbi Symptom distress and quality-of-life assessment at the end of life: the role of proxy response
    Jean S Kutner
    Division of General Internal Medicine, University of Colorado at Denver and Health Sciences Center, Denver, 80262, USA
    J Pain Symptom Manage 32:300-10. 2006
    This study sought to advance understanding of the relationships among proxy and patient reports of symptom distress and quality of life (QOL)...
  89. ncbi Self-proxy agreement and correlates of health-related quality of life in young adults with epilepsy and mild intellectual disabilities
    Friederike Zimmermann
    Department of Psychology, University of Heidelberg, Hauptstrasse 47 51, 69117 Heidelberg, Germany
    Epilepsy Behav 13:202-11. 2008
    ..First, agreement between self-reports and proxy reports of HRQOL was examined. Second, medical and psychological contributions to HRQOL were explored...
  90. pmc The effect of parental mental health on proxy reports of health-related quality of life in children with sickle cell disease
    Julie A Panepinto
    Department of Pediatrics, Children s Research Institute of the Children s Hospital of Wisconsin Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Pediatr Blood Cancer 55:714-21. 2010
    The objectives of this study were to evaluate factors that influence agreement between parent-proxy and child self-report of health-related quality of life (HRQL) in sickle cell disease...
  91. ncbi [Limiting life-prolonging treatments: a practical guidance reflecting the current legislation in Germany]
    G Marckmann
    Institut für Ethik und Geschichte der Medizin, Universitat Tubingen
    Dtsch Med Wochenschr 135:570-4. 2010
    ..In accordance with prior high court rulings, the new Civil Law legislation in Germany provides three standards for proxy decision making: (1) the patients' written advance directive, (2) oral treatment preferences and substituted ..
  92. ncbi Difference in reported pre-morbid health-related quality of life between ARDS survivors and their substitute decision makers
    Damon C Scales
    Department of Critical Care Medicine, Sunnybrook and Women s Health Sciences Centre, 2075 Bayview Avenue, M4N 3M5, Toronto, Canada
    Intensive Care Med 32:1826-31. 2006
    ..Substitute decision makers may consider the pre-morbid health status of their critically ill loved one when making treatment decisions on her/his behalf...
  93. pmc Reliability and validity of the Infant and Toddler Quality of Life Questionnaire (ITQOL) in a general population and respiratory disease sample
    Hein Raat
    Department of Public Health, Erasmus MC University Medical Center Rotterdam, P O Box 2040, Rotterdam, ZH, 3000, CA, The Netherlands
    Qual Life Res 16:445-60. 2007
    ....
  94. ncbi Quality of life on admission to the intensive care: can we query the relatives?
    Jose Hofhuis
    Gelre Lukas Hospital Apeldoorn, Department of Intensive Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Intensive Care Med 29:974-9. 2003
    ..To study whether the Short Form-36 questionnaire can be used to assess the patient's quality of life on admission to the ICU by use of proxies in both scheduled and emergency admissions...
  95. doi Quality of life of children with CP: condition-specific instrument and proxy reports
    Elise Davis
    Dev Med Child Neurol 50:167. 2008
  96. pmc Proxy measurements in multiple sclerosis: agreement between patients and their partners on the impact of multiple sclerosis in daily life
    F A H van der Linden
    Department of Neurology, VU University Medical Centre, PO Box 7057, 1007 MB Amsterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 77:1157-62. 2006
    ..In these situations proxies may provide valuable information, provided we can be certain that proxies and patients give consistent ratings...
  97. ncbi Proxy reporting in after-death interviews: the use of proxy respondents in retrospective assessment of chronic diseases and symptom burden in the terminal phase of life
    M Klinkenberg
    Department of Social Medicine and Institute for Research in Extramural Medicine, VU University Medical Centre, Amsterdam, The Netherlands
    Palliat Med 17:191-201. 2003
    ..On an individual level this can be concluded only for chronic diseases with clearly observable consequences...
  98. pmc Measuring health-related quality of life in young adolescents: reliability and validity in the Norwegian version of the Pediatric Quality of Life Inventory 4.0 (PedsQL) generic core scales
    Trude Reinfjell
    Department of Psychology, Norwegian University of Science and Technology NTNU, N 7491, Trondheim, Norway
    Health Qual Life Outcomes 4:61. 2006
    ..The purpose of the current study was to evaluate the psychometric properties of the Norwegian translation of the Pediatric Quality of Life Inventory (PedsQL) 4.0 generic core scale in a sample of healthy young adolescents...
  99. ncbi Parent-proxy and child self-reported health-related quality of life: using qualitative methods to explain the discordance
    Elise Davis
    School of Health and Social Development, Faculty of Health, Medicine, Nursing and Behavioural Sciences, Deakin University, Burwood, Victoria, 3125, Australia
    Qual Life Res 16:863-71. 2007
    Although parent-proxy reports of health-related quality of life (HRQOL) are only moderately correlated with child reported HRQOL, it remains unknown why these scores differ...
  100. ncbi A comparison of patient and proxy symptom assessments in advanced cancer patients
    C L Nekolaichuk
    Department of Oncology, Cross Cancer Institute, Edmonton, Alberta, Canada
    Palliat Med 13:311-23. 1999
    The purpose of this study was to compare patient and proxy (physician and nurse) assessments of symptoms in advanced cancer patients. The sample consisted of 49 patients with advanced cancer admitted to an acute palliative care unit...
  101. ncbi Preferring proxy-agency: impact on self-efficacy for exercise
    Christopher A Shields
    School of Recreation Management and Kinesiology, Acadia University, Wolfville, NS, Canada
    J Health Psychol 11:904-14. 2006
    We examined: (a) the social-cognitions of those who differ in preferred level of proxy-assistance in both proxy-led and independent exercise contexts; and (b) the relationships between proxy-agency and reliance...

Research Grants76

  1. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
    ..abstract_text> ..
  2. Genetic variation and regulatory networks: Mechanisms and complexity
    DANA PE ER; Fiscal Year: 2009
    ..These tools will be made publicly available, including a friendly graphical user interface and visualization. ..
  3. Biochemistry and Function of a Novel Bacterial Photosensory Two-Component System
    MELISSA MARKS; Fiscal Year: 2010
    ..Light is a ubiquitous environmental signal that can act as a proxy for whether a cell is inside or outside a host organism...
  4. Diesel, Allergens and Gene Interaction and Child Atopy
    Grace LeMasters; Fiscal Year: 2009
    ..ETS exposure is a major contributor to childhood respiratory disorders. Nicotine and cotinine measures serve as a proxy for systemic exposure to over 4700 chemicals present in ETS, many with pro-inflammatory properties, including ..
  5. Neurotrophic Factors: Genetic Variation and Serum Levels in Brain Aging
    Sudha Seshadri; Fiscal Year: 2010
    ..Brain MRI and cognitive tests can identify proxy measures of reserve and subclinical markers (heritable endophenotypes) of AD- and vascular pathology...
  6. CANCER AND CHANGING TRENDS IN US MORTALITY INEQUITIES: 1960-2004
    Nancy Krieger; Fiscal Year: 2010
    ..breast, prostate, cervix, stomach, AND liver CANCER [TEXT DELETED], AND (2) CREATE A DEATH CERTIFICATE QUALITY PROXY (DCQP) MEASURE, BASED ON THE COUNTY DATA FOR CANCER MORTALITY DUE TO ILL-DEFINED CANCERS, ALL- CAUSE MORTALITY DUE ..
  7. Biological &Environmental Mediators of Vitamin D and Aggressive Prostate Cancer
    ADAM BRYANT MURPHY; Fiscal Year: 2013
    ..Therefore we seek to 1) validate serum vitamin D as a proxy for intra-prostatic vitamin D levels using the expressed prostatic secretion from 260 prostatectomy specimen;2) ..
  8. Epidemiology of testicular cancer in the Utah population
    Mia Hashibe; Fiscal Year: 2012
    ..We also have access to geocoded data on proximity to specific agricultural activities (as a proxy for pesticide exposure) and exposure to contaminants in drinking water in Utah, which will be linked to the UPDB ..
  9. Tick feeding regulation by orthologous tick saliva serine protease inhibitors
    Albert Mulenga; Fiscal Year: 2013
    ..SG) serpin, and validated that 2 of the serpins (S), AamS6 and AamS8 are secreted into tick saliva, which is proxy for their injection into the host during tick feeding...
  10. Understanding the malaria-poverty vicious circle
    MARCIA CALDAS DE CASTRO; Fiscal Year: 2010
    ..as measured by microscopy), reducing the potential bias observed in studies that considered fever as a proxy for malaria...
  11. Effectiveness of ICP Monitoring in Pediatric Traumatic Brain Injury
    TELLEN BENNETT; Fiscal Year: 2013
    ..Aim 2 is to validate the accuracy of database codes in the linked dataset and a proxy poor functional outcome, survival with tracheostomy and gastrostomy, by conducting a three-year prospective cohort ..
  12. A protein array platform for anti-citrulline antibodies in Rheumatoid Arthritis
    Ji Qiu; Fiscal Year: 2013
    ..Despite being an excellent proxy assay for diagnosis, anti-CCP positivity does not reveal any information about the actual underlying antigens that ..
  13. Geobiological approaches to understanding pulmonary infections in situ
    Dianne K Newman; Fiscal Year: 2013
    ..Incorporation of 2H from water into lipids will be developed as a novel proxy for in situ growth rates, and spatial mapping of 15N incorporation into proteins using nanoSIMS will be used to ..
  14. Aging Together: Brothers and Sisters of the Wisconsin Longitudinal Study
    John Robert Warren; Fiscal Year: 2013
    ..Considering the age of many of the participants, we will conduct proxy interviews for members of the sample who are not currently able to participate directly...
  15. Detection of Glaucoma Progression with Macular OCT Imaging
    Kouros Nouri-Mahdavi; Fiscal Year: 2013
    ..advanced glaucoma, and therefore, detection of worsening in one or more macular outcome measures can be used as a proxy for subsequent visual field progression...
  16. Community Exercise and Metabolic Syndrome in Black Families
    Diane M Becker; Fiscal Year: 2012
    ..Endpoints also include a proxy for improved vascular health and conversion from having the metabolic syndrome to normal...
  17. Selecting Best Neuroleptic Treatment for Veterans with Schizophrenia
    Erin A Hazlett; Fiscal Year: 2013
    ..Our pilot data suggest that PPI measures are a potential proxy for caudate function and may eventually serve as useful intermediary treatment predictors...
  18. Serology as a measure of exposure and duration of infection in malaria trials
    WENDY PRUDHOMME O'MEARA; Fiscal Year: 2013
    ..infections in a cross-sectional survey, is often used to quantify the burden of infection and is also used as a proxy for transmission intensity...
  19. Integration of Genomics & Transcriptomics in Normal Twins & Major Depression
    Patrick F Sullivan; Fiscal Year: 2010
    ..We have previously shown that PB is a reasonable proxy for CNS expression. We will employ an advance modeling framework...
  20. Statistical Methods to Correct for Proxy Bias in Studies of Older Adults
    MICHELLE DENISE SHARDELL; Fiscal Year: 2013
    ..of biostatistics and gerontology;and 2) to develop statistical methods needed to more appropriately use data from proxy respondents (e.g., relatives or care givers) in epidemiological studies of elderly hip-fracture patients...
  21. Human Maternal/Fetal Exposures to PBDEs and their Metabolites During Development
    Tracey J Woodruff; Fiscal Year: 2013
    ..Human exposure and epidemiologic studies have largely characterized in utero exposure by measuring chemicals in proxy biological specimens, such as maternal blood and umbilical cord blood collected at delivery...
  22. Efficacy of a Novel Neuroprotective Compound in Nonhuman Primate
    Andrew A Pieper; Fiscal Year: 2013
    ..Rhesus macaques (Macaca mulatta) provide a useful proxy for efficacy in the human, as they demonstrate many features of human physiology, anatomy and behavior...
  23. Contribution of ASIC channels to intrinsic chemosensitivity of NTS neurons
    Rafiq Huda; Fiscal Year: 2013
    ..Central chemosensory neurons detect changes in brain pH as a proxy for changes in PCO2 and cause compensatory changes in respiration to maintain homeostasis of these parameters...
  24. The effects of aging on experimental models of pain inhibition and facilitation
    Joseph L Riley; Fiscal Year: 2013
    ..analgesia, and tests that involve pain facilitation;temporal summation, impaired decay of subthreshold pain (proxy for central sensitization), and a prolonged protocol which we have found produces greater temporal sensitization ..
  25. Foot Progression Angle in Individuals with Diabetes &Peripheral Neuropathy
    ERICKA NAYRAM MERRIWETHER; Fiscal Year: 2013
    ..Therefore, peak plantar pressure is frequently used as a proxy measure of risk for skin breakdown and subsequent non-traumatic lower extremity amputation...
  26. Cognitive-enhancing DA Medications for Cocaine Dependence
    JOY MARIE SCHMITZ; Fiscal Year: 2013
    ..by which DA medications may operate to change cocaine use, providing a potential neurobehavioral marker or proxy for severity of cocaine-related deficits and treatment-related improvement...
  27. Evaluation of BRAF-inhibitor induced alterations in glucose metabolism
    Nicholas Theodosakis; Fiscal Year: 2013
    ..FDG-PET, which uses uptake of a radioactive glucose analog as a proxy for metabolic activity, is used to image melanoma in the clinic due to the tumors'highly elevated glucose ..
  28. LONGITUDINAL STUDY OF MEXICAN AMERICAN ELDERLY HEALTH
    Kyriakos S Markides; Fiscal Year: 2013
    ..information on circumstances surrounding the subjects'death, which we have done over the years by using a proxy death questionnaire...
  29. Cognitive and Emotional Sources of Wisdom in Decision Making Across the Lifespan
    Eric J Johnson; Fiscal Year: 2012
    ..For example, domain-general knowledge may correlate with domain-specific (i.e., semantic) knowledge, or it may proxy for a number of other abilities that improve with age, including domain-specific process expertise (i.e...
  30. Molecular Epidemiology of Pancreatic Cancer
    Paige M Bracci; Fiscal Year: 2010
    ..Innovative hypotheses to advance PC research (e.g. SNPs);3. Expertise of lab faculty and facilities;4. No proxy interviews;5. Clinic-based cases will diminish case loss due to poor survival;6...
  31. Nanowell-based single-cell technology for characterizing clinical samples ex vivo
    JOHN CHRISTOPHER LOVE; Fiscal Year: 2012
    ..These cells have been a convenient proxy because blood is the most accessible compartment and the number of cells recovered can be large...
  32. Cell type-specific calcium imaging during hippocampus-dependent memory
    Larry S Zweifel; Fiscal Year: 2013
    ..neuronal spikes are associated with large intracellular calcium conductances, calcium indicators can be used as a proxy for neuronal activation...
  33. Developing and Testing a Novel Geometric Model of Protein Adaptation
    DANIEL MICHAEL WEINREICH; Fiscal Year: 2013
    ..to a novel panel of mutations in TEM b-lactamase, whose effect on drug resistance will be characterized as a proxy for fitness...
  34. Measuring and Explaining Unintended Pregnancy in the United States, 1987-2009
    Lawrence B Finer; Fiscal Year: 2013
    ..data alone for monitoring population trends in unintended pregnancy risk and protection that can be used as a proxy for unintended pregnancy rates themselves, but can be implemented more frequently and less expensively and thus ..
  35. Microbial community profiling of sewage contamination in the Great Lakes
    Sandra L McLellan; Fiscal Year: 2010
    ..will characterize rapidly evolving hypervariable regions in ribosomal RNA (rRNA) genes, each of which serves as a proxy for the occurrence of a microorganism in a sample...
  36. Neighborhood Effects on Drug Use Among African American Adults
    Claire E Sterk; Fiscal Year: 2012
    ..Census block groups will be used as proxy for neighborhoods...
  37. New 3D tumor models to rapidly test drugs for brain cancer therapy
    Miqin Zhang; Fiscal Year: 2013
    ..3D system made of complex scaffold of chitosan and alginate (CA), two naturally occurring polymers that bear proxy structure of glycosaminoglycans, a major component of native extracellular matrix (ECM)...
  38. Ethical issues in Dementia Research involving Surrogates and Study Partners
    BETTY E BLACK; Fiscal Year: 2013
    ..dementia patients who lack capacity to give informed consent always requires surrogate decision makers to provide proxy consent...
  39. Impact of Food Marketing and Cross-Promotions on Preschoolers'Dietary Intake
    Meghan R Longacre; Fiscal Year: 2013
    ..through repeated 7-day recalls of FF and SBC consumption and four 24-hour dietary recalls with parents as a proxy. Height and weight will be objectively measured...
  40. Paternal Age Related Schizophrenia as a Discrete Disorder
    Dolores Malaspina; Fiscal Year: 2010
    ..our earlier-funded NIMH CMHC in Schizophrenia) we found that sporadic cases with paternal age >35 years (a proxy for PARS) had distinct patterns of symptoms, cognition, course and sex-differences versus other (NonPARS) cases...
  41. Biomarkers of Injury and Outcome in Pro-TECT III (BIO-ProTECT)
    MICHAEL ROSS FRANKEL; Fiscal Year: 2013
    ..the ability of promising biomarkers to predict outcome in TBI, b) demonstrate the utility of biomarkers as proxy indicators of the clinical effects of treatment with progesterone, and c) provide better definition of treatment ..
  42. Comprehensive Electronic Support System for Treatment of Cancer-Related Symptoms
    Jennifer L Steel; Fiscal Year: 2010
    ..The efficacy of the CECSS will be evaluated using patient-reported outcomes, proxy rated outcomes, measures of health care utilization, and biological markers (e.g...
  43. Dynamics &energetics of p38a kinase regulation by ligands
    A Joshua Wand; Fiscal Year: 2013
    ..relaxation methods have enabled the use of measures-of-motion between conformational states of a protein as a proxy for conformational entropy...
  44. Discovery of GJB2 cis-regulatory elements and missing DFNB1 mutation
    ELLEN SHIELDS WILCH; Fiscal Year: 2013
    ..Second, by chromosome conformation capture carbon-copy (5C) in a number of proxy cell lines, we will identify regions from within the DFNB1 locus that interact specifically with DNA at or near ..
  45. Patient Care Outcomes at End-of-Life for Older Adults in ICU
    Jennifer B Seaman; Fiscal Year: 2013
    ..shown that palliative care consultation can improve EOL care, but implementation in the ICU is inconsistent and proxy measures are commonly employed...
  46. Quality of Life in Intersexuality: A Pediatric Clinical and Research Tool
    David E Sandberg; Fiscal Year: 2010
    ..The objective of this study is to develop validated parent-proxy report (Quality of Life Disorders of Sex Development Questionnaire, QoL-DSDQ) and parent self-report (Quality of ..
  47. Crossover Study on Human Exposure to Phthalates and Male Fertility
    Russ B Hauser; Fiscal Year: 2013
    ..Modern techniques of transcript profiling (i.e., microarrays and deep sequencing) provide a non-invasive proxy for the testis...
  48. Development of a new technology for assessing pediatric pain (NTAP)
    Jeannie S Huang; Fiscal Year: 2013
    ..Suboptimal pain assessment is particularly prevalent in children, who often rely on pain assessment by proxy which has been shown repeatedly to poorly correlate with patients'self-reports of pain...
  49. 2/2-Attaining and Maintaining Wellness in OCD
    Edna B Foa; Fiscal Year: 2013
    ..24), patients (expected n=100) who attain wellness (using a Yale-Brown Obsessive Compulsive Scale score d 14 as a proxy) will be randomized to continue their SRI or switch to pill placebo and followed for 24 weeks...
  50. Relation of Alignment and Other Risk Factors to Knee OA
    DAVID TOBIN FELSON; Fiscal Year: 2010
    ..To develop proxy measures for alignment that can be used in other studies...
  51. Traumatic Brain Injury Clinical Trials Network
    Joseph H Ricker; Fiscal Year: 2010
    ..understanding the mechanisms that impact recovery and interventional efficacy, as well as the establishment of proxy measures that can predict long term outcome is an important role of the TBI clinical trials network...
  52. The Geography of Violence and alcohol in Boston
    Robert I Lipton; Fiscal Year: 2010
    ..We will examine changes overtime and include changes in drug market locations (as measured by the proxy, drug arrest locations)...
  53. Voices of children and adolescents with incurable cancer on Phase I or II Trials
    Pamela S Hinds; Fiscal Year: 2011
    ..trials to support drug labeling, including clear language requiring PROs in pediatrics and not parent or clinician proxy reports...
  54. Biophysical Measure To Predict Pressure Ulcers In Nursing Home Residents
    Barbara M Bates-Jensen; Fiscal Year: 2012
    ..Skin tone of NH residents will be assessed using color tiles rather than by proxy measures of ethnicity as in previous research...
  55. Constrained Provider Choice: The Effect of a TBA Ban on Morality
    Edward N Okeke; Fiscal Year: 2013
    ..To proxy for variation in the potential effectiveness of the law we exploit a unique dataset on the location of all health ..
  56. Validation of PROMIS Measures in Children with Brain Tumors
    Jin Shei Lai; Fiscal Year: 2013
    ..Parents of all children will complete the parent-proxy version;patients aged 8-17 (anticipated n=420) will complete the self-reported version of the pediatric PROMIS...
  57. Genomics in the Clinic: Identity, Responsibility and Choice
    Linda M Hunt; Fiscal Year: 2013
    ..and treatments are only in the developmental stage for most conditions, many urge the use of race/ethnicity as a proxy for presumed genetic factors...
  58. Epidemiology of Gonoccoccal Subpopulations
    Jonathan M Zenilman; Fiscal Year: 2010
    ..are associated with behavioral risk factors and sexual network information, hypothesizing that typing can act as proxy data for behavioral variables...
  59. HOST AND MICROBIOLOGICAL DETERMINANTS OF INFECTIOUSNESS IN PATIENTS WITH DRUG SEN
    KEERTAN UNKHA DHEDA; Fiscal Year: 2013
    ..infection in household contacts of active TB cases (submitted for publication;NEJM), and can therefore serve as a proxy marker of infectiousness. This technology has not been applied in South Africa or to patients with XDR-TB...
  60. Evaluation and Integration of an Automatic Fall Prediction System
    William D Kearns; Fiscal Year: 2010
    ..Two goals are to determine if information generated by MTS can be a proxy for SGB and if predictions of a fall improve as changes in MTS occur closer in time to falls...
  61. Risk Factors Associated with Unintended Pregnancies
    Evelyn Angel James; Fiscal Year: 2013
    ..these earlier studies were limited in a number of ways including the use of repeat elective termination as a proxy for repeat unintended pregnancy, retrospective study designs, and samples that excluded older, reproductively-..
  62. An analysis of environmental risk factors for obesity
    Walker Poston; Fiscal Year: 2007
    ..stratified by household income level (our pilot data suggest that household income level is a powerful proxy variable for the presence of obesity-producing environmental factors)...
  63. Intra-Urban Health Assessed by Remote-Sensing and GIS
    John Weeks; Fiscal Year: 2005
    ..to a minimally acceptable standard; and (6) to evaluate how well the remotely-sensed data can, on their own as a proxy, model the intra-urban inequalities in health in ways that might lead these data to be used as health monitoring ..
  64. APPROPRIATE DENTAL CARE UNDER DIFFERENT PAYMENT SYSTEMS
    HERBERT HAZELKORN; Fiscal Year: 1991
    ..Thus the dollar will act as a proxy for the amount and type (because of the difference in the cost of each procedure) of treatment recommended by the ..
  65. MEASURING QOL DURING TREATMENT FOR SLEEP APNEA
    JEANNETTE BREUGELMANS; Fiscal Year: 2000
    ..of acquiring health status information on a sleep apnea patient's functioning and quality of life by partners as proxy raters. Sleep apnea is a common sleep disorder and it is estimated to affect 2-4% of middle-aged adults...
  66. End-of-Life Research Ethics: Concerns, Approaches, and Impact
    Susan Hickman; Fiscal Year: 2009
    ..recognizing that research conducted at the EOL raises complex ethical questions related to consent, capacity, proxy decision-making, and the evaluation of risks and benefits that may inhibit the conduct of this vital research and ..
  67. TRIAL OF FAS PREVENTION IN AMERICAN INDIAN COMMUNITIES
    Philip May; Fiscal Year: 2001
    ..of specific prevention components and change in age-specific FAS prevalence rates and specific secondary (proxy) measures in six American Indian communities (4 prevention and 2 control); to measure change in adult drinking and ..
  68. LONGITUDINAL STUDY OF RURAL PHYSICIAN RETENTION
    Donald Pathman; Fiscal Year: 2000
    ..of their future practice employment tenure, to validate a refined version of a commonly used survey-derived proxy measure for retention. Retention analyses will use the techniques of mufti-variable survival analysis...
  69. Genetics, Genomic Research, and Consent: Attitudes of Pediatric Cancer Survivors
    ANDREA PATENAUDE; Fiscal Year: 2007
    ..to their willingness to donate genetic material for genomic research, and * their attitudes towards parental proxy permission for use of a minor child's DNA for genetic testing and genomic research, 3...
  70. PROXY DECISION MAKING IN MENTAL RETARDATION
    Kathleen Fisher; Fiscal Year: 2006
    ..In a pilot study, proxy decision making was found to affect the provision of appropriate health care services for individuals with MR and, ..
  71. IOWA AND MISSOURI RADON LUNG CANCER STUDIES
    R Field; Fiscal Year: 2007
    ..Inaccurate dose assessment of radon exposure, a high percentage of proxy respondents, inadequate pathologic review, and low residential radon concentrations led to exposure ..
  72. Voice-Related Quality of Life in Dysphonic Children
    DIANE HEATLEY; Fiscal Year: 2004
    ..Questionnaire items will be developed and tested for child reporting and parent proxy for the following age groups: Toddler (2-4), Young Children (5-7), School age (8-12) and Adolescent (13-18)...
  73. Cultural Influences on Health Beliefs and Practices
    CAYLA TEAL; Fiscal Year: 2006
    ..Intermediate goals include examining race and ethnicity as a proxy variable for understanding disparate health outcomes and the development of a multidimensional instrument for ..
  74. Hospital Care IDUs with Soft Tissue Infections
    Traci Takahashi; Fiscal Year: 2004
    ..the proposed study are to (1) describe hospitalizations for illicit drug users with soft tissue infections (as a proxy for injection drug use-related soft tissue infections), (2) provide the first national estimates of their ..
  75. Are Volume Standards Accurate Measures of Quality?
    Laurent Glance; Fiscal Year: 2005
    ..high-volume hospitals has been advocated for high-risk surgery on the grounds that procedure volume is a quality proxy. With the launching of the Leapfrog Group safety initiative, these policy recommendations are now being ..