very low birth weight infant

Summary

Summary: An infant whose weight at birth is less than 1500 grams (3.3 lbs), regardless of gestational age.

Top Publications

  1. ncbi Cardiocirculatory effects of patent ductus arteriosus in extremely low-birth-weight infants with respiratory distress syndrome
    Senji Shimada
    Department of Pediatrics, Iwate Medical University, Morioka, Iwate, Japan
    Pediatr Int 45:255-62. 2003
  2. ncbi Predictors of mortality in very low birth weight neonates in India
    S Basu
    Department of Paediatrics, Division of Neonatology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India
    Singapore Med J 49:556-60. 2008
  3. ncbi Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network
    Barbara J Stoll
    Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Pediatrics 110:285-91. 2002
  4. ncbi Outcomes in young adulthood for very-low-birth-weight infants
    Maureen Hack
    Department of Pediatrics, Case Western Reserve University, Cleveland, USA
    N Engl J Med 346:149-57. 2002
  5. ncbi Glucose regulation in young adults with very low birth weight
    Petteri Hovi
    Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
    N Engl J Med 356:2053-63. 2007
  6. ncbi Trends in mortality and morbidity for very low birth weight infants, 1991-1999
    Jeffrey D Horbar
    University of Vermont Department of Pediatrics, Burlington, Vermont Vermont Oxford Network, Burlington, Vermont, USA
    Pediatrics 110:143-51. 2002
  7. ncbi Maternal posttraumatic stress response after the birth of a very low-birth-weight infant
    A Kersting
    Department of Psychiatry, University of Muenster, Albert Schweitzer Str 11, Muenster D 48129, Germany
    J Psychosom Res 57:473-6. 2004
  8. ncbi Mutations of genes involved in the innate immune system as predictors of sepsis in very low birth weight infants
    Peter Ahrens
    Department of Pediatrics, University of Lubeck, Germany
    Pediatr Res 55:652-6. 2004
  9. ncbi Patent ductus arteriosus in micropreemies and full-term infants: the relative merits of surgical ligation versus indomethacin treatment
    Danny C Little
    Scott and White Hospital, Temple, Texas 76508, USA
    J Pediatr Surg 38:492-6. 2003
  10. ncbi Neurodevelopmental and growth outcomes of extremely low birth weight infants after necrotizing enterocolitis
    Susan R Hintz
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, 750 Welch Rd, Suite 315, Palo Alto, CA 94304, USA
    Pediatrics 115:696-703. 2005

Detail Information

Publications303 found, 100 shown here

  1. ncbi Cardiocirculatory effects of patent ductus arteriosus in extremely low-birth-weight infants with respiratory distress syndrome
    Senji Shimada
    Department of Pediatrics, Iwate Medical University, Morioka, Iwate, Japan
    Pediatr Int 45:255-62. 2003
    ..The objective of the present study was to evaluate the effects of hsPDA on the left ventricular output (LVO) and organ blood flows in ELBW infants with RDS...
  2. ncbi Predictors of mortality in very low birth weight neonates in India
    S Basu
    Department of Paediatrics, Division of Neonatology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India
    Singapore Med J 49:556-60. 2008
    ..Very low birth weight (VLBW) neonates constitute approximately 4-7 percent of all live births and their mortality is very high. The objective of the present study was to determine the predictors of mortality in VLBW neonates...
  3. ncbi Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network
    Barbara J Stoll
    Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Pediatrics 110:285-91. 2002
    ....
  4. ncbi Outcomes in young adulthood for very-low-birth-weight infants
    Maureen Hack
    Department of Pediatrics, Case Western Reserve University, Cleveland, USA
    N Engl J Med 346:149-57. 2002
    ..Very-low-birth-weight infants (those weighing less than 1500 g) born during the initial years of neonatal intensive care have now reached young adulthood...
  5. ncbi Glucose regulation in young adults with very low birth weight
    Petteri Hovi
    Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
    N Engl J Med 356:2053-63. 2007
    ..We assessed glucose tolerance and insulin sensitivity and measured serum lipid levels and blood pressure in young adults with very low birth weight...
  6. ncbi Trends in mortality and morbidity for very low birth weight infants, 1991-1999
    Jeffrey D Horbar
    University of Vermont Department of Pediatrics, Burlington, Vermont Vermont Oxford Network, Burlington, Vermont, USA
    Pediatrics 110:143-51. 2002
    ..Medical care for very low birth weight (VLBW) infants and their mothers has changed dramatically during the 1990s, yet it is unclear how these changes have affected mortality and morbidity...
  7. ncbi Maternal posttraumatic stress response after the birth of a very low-birth-weight infant
    A Kersting
    Department of Psychiatry, University of Muenster, Albert Schweitzer Str 11, Muenster D 48129, Germany
    J Psychosom Res 57:473-6. 2004
    ..The present study is the first to investigate the posttraumatic stress response of mothers after the birth of a VLBW infant in a prospective longitudinal study...
  8. ncbi Mutations of genes involved in the innate immune system as predictors of sepsis in very low birth weight infants
    Peter Ahrens
    Department of Pediatrics, University of Lubeck, Germany
    Pediatr Res 55:652-6. 2004
    ..5% versus 2.4% in homozygous IL6-174G carriers with prophylaxis; p = 0.033)...
  9. ncbi Patent ductus arteriosus in micropreemies and full-term infants: the relative merits of surgical ligation versus indomethacin treatment
    Danny C Little
    Scott and White Hospital, Temple, Texas 76508, USA
    J Pediatr Surg 38:492-6. 2003
    ..Treatment of ductus arteriosus is controversial. The merits and timing of ductus ligation versus indomethacin treatment were compared...
  10. ncbi Neurodevelopmental and growth outcomes of extremely low birth weight infants after necrotizing enterocolitis
    Susan R Hintz
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, 750 Welch Rd, Suite 315, Palo Alto, CA 94304, USA
    Pediatrics 115:696-703. 2005
    ..The objective of this study was to compare growth, neurologic, and cognitive outcomes among ELBW survivors of SurgNEC and MedNEC with NoNEC at 18 to 22 months' corrected age...
  11. ncbi Maternal psychological distress and parenting stress after the birth of a very low-birth-weight infant
    L T Singer
    Department of Pediatrics, School of Medicine, Case Western Reserve University, MetroHealth Medical Center, Cleveland, Ohio, USA
    JAMA 281:799-805. 1999
    ..Few studies document how parents adapt to the experience of a very low-birth-weight (VLBW; <1500 g) birth despite societal concerns about the ethics and justification of intensive care for these infants...
  12. ncbi Epidemiological, clinical, and microbiological characteristics of late-onset sepsis among very low birth weight infants in Israel: a national survey
    Imad R Makhoul
    Department of Neonatology, Rambam Medical Center and Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    Pediatrics 109:34-9. 2002
    ..Variables with P </=.1 were then tested by a multiple logistic regression for assessing the net effect of each variable on the risk for LOS...
  13. ncbi Accuracy of methods for calculating postnatal growth velocity for extremely low birth weight infants
    Aloka L Patel
    Department of Pediatrics, Rush University Medical Center, Chicago, IL 60612, USA
    Pediatrics 116:1466-73. 2005
    ..The accuracy of all models was compared with actual GVs calculated from daily weight measures for a group of ELBW infants...
  14. ncbi Adverse neurodevelopmental outcomes among extremely low birth weight infants with a normal head ultrasound: prevalence and antecedents
    Abbot R Laptook
    Brown Medical School, Providence, Rhode Island, USA
    Pediatrics 115:673-80. 2005
    ..This study examined the prevalence of and risk factors for CP and impaired mental development among ELBW infants with a normal HUS...
  15. ncbi Improved survival rates with increased neurodevelopmental disability for extremely low birth weight infants in the 1990s
    Deanne Wilson-Costello
    Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA
    Pediatrics 115:997-1003. 2005
    ....
  16. ncbi Hyperglycemia is a risk factor for early death and morbidity in extremely low birth-weight infants
    Stephane P Hays
    USDA ARS Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates St, Houston, TX 77030, USA
    Pediatrics 118:1811-8. 2006
    ....
  17. ncbi Consequences of delayed surgical closure of patent ductus arteriosus in very premature infants
    Sophie Jaillard
    Service de Chirurgie, Polyclinique du Bois, Lille, France
    Ann Thorac Surg 81:231-4. 2006
    ..The aim of this study was to assess short-term and mid-term effects of delayed surgical closure of the ductus arteriosus on respiratory and digestive outcome in extremely preterm infants...
  18. ncbi Histologic chorioamnionitis and severity of illness in very low birth weight newborns
    Claudio De Felice
    Neonatal Intensive Care Unit, Azienda Ospedaliera Universitaria Senese, Policlinico Le Scotte, Viale M Bracci 16, I 53100 Siena, Italy
    Pediatr Crit Care Med 6:298-302. 2005
    ..In this study, the relationships among HCA, initial illness severity, and neonatal outcomes were analyzed in very low birth weight (VLBW) newborns admitted to the neonatal intensive care unit...
  19. ncbi Neurodevelopmental and functional outcomes of extremely low birth weight infants in the National Institute of Child Health and Human Development Neonatal Research Network, 1993-1994
    B R Vohr
    Women and Infants Hospital, Providence, Rhode Island 02905, USA
    Pediatrics 105:1216-26. 2000
    ....
  20. ncbi Validation of the National Institutes of Health consensus definition of bronchopulmonary dysplasia
    Richard A Ehrenkranz
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Pediatrics 116:1353-60. 2005
    ..The objective of this study was to determine the predictive validity of the severity-based, consensus definition of BPD...
  21. ncbi Preterm male infants need more initial respiratory and circulatory support than female infants
    E Elsmén
    Department of Paediatrics, Lund University Hospital, Sweden
    Acta Paediatr 93:529-33. 2004
    ..The aim of this study was to investigate possible gender-related differences in clinical parameters during the first week of life that could explain the higher morbidity and mortality of preterm male infants...
  22. doi Depression in young adults with very low birth weight: the Helsinki study of very low-birth-weight adults
    Katri Raikkonen
    Department of Psychology, University of Helsinki, PO Box 9, FI 00014 Helsinki, Finland
    Arch Gen Psychiatry 65:290-6. 2008
    ..Little is known about the mental health outcomes of very low-birth-weight (VLBW) (< 1500 g) infants in young adulthood...
  23. ncbi Patterns of motor disability in very preterm children
    Melanie Bracewell
    Academic Division of Child Health, University of Nottingham, United Kingdom
    Ment Retard Dev Disabil Res Rev 8:241-8. 2002
    ..Interventions to prevent cerebral palsy or to reduce these late disabilities in very preterm children are needed...
  24. ncbi Changes in pathogens causing early-onset sepsis in very-low-birth-weight infants
    Barbara J Stoll
    Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    N Engl J Med 347:240-7. 2002
    ....
  25. ncbi Prenatal risk factors for severe retinopathy of prematurity among very preterm infants of the Australian and New Zealand Neonatal Network
    Brian A Darlow
    Department of Paediatrics, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
    Pediatrics 115:990-6. 2005
    ..To identify prenatal and perinatal risk factors for clinically severe (stage 3 or 4) retinopathy of prematurity (ROP)...
  26. ncbi Summary proceedings from the bronchopulmonary dysplasia group
    Michele C Walsh
    Division of Neonatology, Rainbow Babies and Children s Hospital, Department of Pediatrics, Case Western Reserve University, 11100 Euclid Ave, Mailstop 6010, Cleveland, Ohio 44106 6010, USA
    Pediatrics 117:S52-6. 2006
    ..Finally, we discuss trial-design issues that are common to all neonatal studies...
  27. ncbi Differential development of infants at risk for psychopathology: the moderating role of early maternal responsivity
    M Laucht
    Central Institute of Mental Health, Department of Child and Adolescent Psychiatry and Psychotherapy, Mannheim, Germany
    Dev Med Child Neurol 43:292-300. 2001
    ..These findings stress the importance of early parenting in the behavioural development of at-risk children...
  28. ncbi Incidence and risk factors for retinopathy of prematurity in very low and in extremely low birth weight infants in a unit-based approach in southern Brazil
    J B Fortes Filho
    Department of Ophthalmology, Medical School, Federal University of Rio Grande do Sul and Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil
    Eye (Lond) 23:25-30. 2009
    ..To analyse the incidence and risk factors for retinopathy of prematurity (ROP) and survival rates among extremely low birth weight (ELBW) and very low birth weight (VLBW) preterm infants...
  29. doi Bedside detection of low systemic flow in the very low birth weight infant on day 1 of life
    J Miletin
    Department of Paediatrics and Newborn Medicine, Coombe Women and Infants University Hospital, Dolphin s Barn, Dublin 8, Ireland
    Eur J Pediatr 168:809-13. 2009
    ..A capillary refill time of >4 s combined with serum lactate concentrations >4 mmol/l increased the specificity and positive and negative predictive values of detecting a low SVC flow state...
  30. ncbi Relationship between hyperglycemia and retinopathy of prematurity in very low birth weight infants
    Tibor Ertl
    Department of Obstetrics and Gynecology, Medical School, University of Pecs, Pecs, Hungary
    Biol Neonate 89:56-9. 2006
    ..58; 95% CI 1.02-2.45; p < 0.05) were found as significant contributors. Further studies are needed to elucidate the pathophysiological role of hyperglycemia in the development of vasoproliferative retinal disorder...
  31. ncbi The TNF-alpha -308, MCP-1 -2518 and TGF-beta1 +915 polymorphisms are not associated with the development of chronic lung disease in very low birth weight infants
    K Adcock
    Department of Pediatrics, University of Mississippi Medical Center, Jackson, MS, USA
    Genes Immun 4:420-6. 2003
    ..016). These data suggest that these polymorphisms do not play a significant role in determining risk for CLD in preterm infants, but may play a role in other complications in the neonatal period...
  32. pmc Changes in mortality and morbidities among infants born at less than 25 weeks during the post-surfactant era
    S R Hintz
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University Medical Center, 750 Welch Road, Suite 315, Palo Alto, CA 94304, USA
    Arch Dis Child Fetal Neonatal Ed 90:F128-33. 2005
    ..To compare mortality and death or major morbidity (DOMM) among infants <25 weeks estimated gestational age (EGA) born during two post-surfactant era time periods...
  33. ncbi Trends in neonatal morbidity and mortality for very low birthweight infants
    Avroy A Fanaroff
    Department of Pediatrics, Case Western Reserve University, Cleveland, OH
    Am J Obstet Gynecol 196:147.e1-8. 2007
    ..To document the mortality and morbidity of infants weighing 501-1500 g at birth according to gestational age, birthweight, and sex...
  34. ncbi Adverse effects of early dexamethasone in extremely-low-birth-weight infants. National Institute of Child Health and Human Development Neonatal Research Network
    A R Stark
    Brigham and Women s Hospital, Boston, MA 02115, USA
    N Engl J Med 344:95-101. 2001
    ..Early administration of high doses of dexamethasone may reduce the risk of chronic lung disease in premature infants but can cause complications. Whether moderate doses would be as effective but safer is not known...
  35. ncbi Is there evidence that long-term outcomes have improved with intensive care?
    Deanne Wilson-Costello
    Department of Pediatrics, Case Western Reserve University, Cleveland, OH 44106, USA
    Semin Fetal Neonatal Med 12:344-54. 2007
    ....
  36. ncbi Race, Candida sepsis, and retinopathy of prematurity
    Misrak Tadesse
    Department of Pediatrics, Division of Neonatology, Georgetown University Children s Medical Center, Washington, DC 20007, USA
    Biol Neonate 81:86-90. 2002
    ....
  37. ncbi Selective use of vancomycin to prevent coagulase-negative staphylococcal nosocomial bacteremia in high risk very low birth weight infants
    R J Baier
    Department of Pediatrics, Louisiana State University Medical Center, Shreveport 71130 3930, USA
    Pediatr Infect Dis J 17:179-83. 1998
    ..To determine whether vancomycin added to parental nutrition (PN) fluids could prevent nosocomial infections in very low birth weight newborns and which infants would benefit most from prophylaxis...
  38. ncbi Tumor necrosis factor alpha -- 308 polymorphism associated with increased sepsis mortality in ventilated very low birth weight infants
    Curtis L Hedberg
    Department of Pediatrics, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA
    Pediatr Infect Dis J 23:424-8. 2004
    ..The tumor necrosis factor alpha (TNF-alpha) -- 308 G/A single nucleotide polymorphism (SNP) is associated with adverse outcome in septic adult patients...
  39. ncbi Increased interleukin-8 and monocyte chemoattractant protein-1 concentrations in mechanically ventilated preterm infants with pulmonary hemorrhage
    R John Baier
    Department of Pediatrics, Louisiana State University Health Sciences Center, Shreveport 71130 3932, USA
    Pediatr Pulmonol 34:131-7. 2002
    ..These data suggest a pathogenic role for IL-8 and MCP-1 in the development of adverse pulmonary outcome in preterm infants with clinically significant PH...
  40. ncbi Survival of very-low-birth-weight infants according to birth weight and gestational age in a public hospital
    S C Velaphi
    Department of Paediatrics, Chris Hani Baragwanath Hospital and University of the Witwatersrand, Johannesburg
    S Afr Med J 95:504-9. 2005
    ..To determine the survival rates for infants weighing 500 - 1 499 g according to birth weight (BW) and gestational age (GA)...
  41. ncbi [Circulatory failure due to severe cardiac arrhythmia as a result of hyperkalemia in a very low birth weight infant]
    C Apitz
    Universitäts Kinderklinik Würzburg
    Klin Padiatr 218:16-9. 2006
    ..Normally, these high concentrations of potassium are well tolerated of the premature infants. In a few cases hyperkalemia leads to life-threatening cardiac arrhythmias...
  42. ncbi Delivering a very low birth weight infant and the subsequent risk of divorce or separation
    Shailender Swaminathan
    Department of Maternal and Child Health, School of Public Health, University of Alabama at Birmingham, 320 A Ryals Building, 1665 University Boulevard, Birmingham, Alabama 35294 0022, USA
    Matern Child Health J 10:473-9. 2006
    ..The purpose of this paper is to identify the relationship of having a VLBW birth with the probability of divorce or separation in the first two years following delivery...
  43. ncbi Surgical therapy and histological abnormalities in functional isolated small bowel obstruction and idiopathic gastrointestinal perforation in the very low birth weight infant
    Marc Miserez
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Catholic University Leuven, Herestraat 49, B 3000, Leuven, Belgium
    World J Surg 27:350-5. 2003
    ..Survival and long-term gastrointestinal function is excellent. IGIP should be distinguished from NEC...
  44. ncbi Neonatal sepsis of nosocomial origin: an epidemiological study from the "Grupo de Hospitales Castrillo"
    J B López Sastre
    Service of Neonatology, Department of Pediatrics, Hospital Central de Asturias, Oviedo, Spain
    J Perinat Med 30:149-57. 2002
    ..5%) compared with overall sepsis for the remaining etiologies (14.2%) (P < 0.001). In VLBW infants, the mortality rate was significantly higher than in infants weighing > 1500 g (17.3% vs. 6.5%, P < 0.001)...
  45. ncbi Incidence, risk factors of retinopathy of prematurity among very low birth weight infants in Singapore
    V A Shah
    Department of Neonatology, Singapore General Hospital, Singapore
    Ann Acad Med Singapore 34:169-78. 2005
    ..To determine the incidence, risk factors and need for surgery for retinopathy of prematurity (ROP) among very-low-birth-weight (VLBW) infants...
  46. ncbi Incidence, presenting features, risk factors and significance of late onset septicemia in very low birth weight infants. The National Institute of Child Health and Human Development Neonatal Research Network
    A A Fanaroff
    Case Western Reserve University, Cleveland, OH, USA
    Pediatr Infect Dis J 17:593-8. 1998
    ..Our purpose was to determine prospectively the incidence, clinical presentation, laboratory features, risk factors, morbidity and mortality associated with late onset septicemia in infants 501 to 1500 g...
  47. ncbi Postnatal risk factors of retinopathy of prematurity
    Tae Im Kim
    Department of Ophthalmology, Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Korea
    Paediatr Perinat Epidemiol 18:130-4. 2004
    ..In addition, apnoea may not only increase the risk of developing ROP, but may also worsen pre-existing ROP...
  48. ncbi Neurodevelopmental outcomes of extremely low birth weight infants <32 weeks' gestation between 1993 and 1998
    Betty R Vohr
    Department of Pediatrics, Women and Infants Hospital, Providence, RI 02905, USA
    Pediatrics 116:635-43. 2005
    ..It was hypothesized that outcomes would improve over the 3 epochs...
  49. ncbi Variations in practice and outcomes in the Canadian NICU network: 1996-1997
    S K Lee
    Department of Pediatrics, University of British Columbia, British Columbia, Canada
    Pediatrics 106:1070-9. 2000
    ..Previous reports of variations in outcomes among neonatal intensive care units (NICUs) examined only specific subpopulations of interest (eg, very low birth weight [VLBW] infants <1500 g of birth weight [BW])...
  50. pmc Retinopathy of prematurity and risk factors: a prospective cohort study
    Padmani Karna
    Division of Neonatology, Pediatrics and Human Development, Michigan State University, East Lansing, USA
    BMC Pediatr 5:18. 2005
    ....
  51. ncbi Heart rate characteristics: novel physiomarkers to predict neonatal infection and death
    M Pamela Griffin
    Department of Pediatrics, University of Virginia Health System, Charlottesville, Virginia, USA
    Pediatrics 116:1070-4. 2005
    ..The goal of this study was to determine the degree of increased risk for sepsis, urinary tract infection (UTI), and death when these abnormal heart rate characteristics (HRC) were observed...
  52. ncbi Indirect vs direct hospital quality indicators for very low-birth-weight infants
    Jeannette A Rogowski
    RAND, Arlington, VA 22202, USA
    JAMA 291:202-9. 2004
    ..In the absence of direct-quality measures based on patient outcomes, the standards currently in place for many conditions rely on indirect-quality measures such as patient volume...
  53. ncbi The morbidity and survival of very-low-birth-weight infants in Taiwan
    Kuo Inn Tsou
    College of Medicine, Fu Jen Catholic University, Taiwan
    Acta Paediatr Taiwan 44:349-55. 2003
    ....
  54. ncbi Low and very low birth weight in infants conceived with use of assisted reproductive technology
    Laura A Schieve
    Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    N Engl J Med 346:731-7. 2002
    ..It is uncertain, however, whether singleton infants conceived with the use of assisted reproductive technology may also have a higher risk of low birth weight than those who are conceived spontaneously...
  55. ncbi Occurrence of nosocomial bloodstream infections in six neonatal intensive care units
    S B Brodie
    Division of Infectious Disease, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Pediatr Infect Dis J 19:56-65. 2000
    ..Nosocomial bloodstream infections (NBSIs) occur frequently in neonatal intensive care units (NICUs) and are associated with substantial morbidity and mortality. Little has been published regarding variation in NBSI among institutions...
  56. pmc Improved outcomes for very low birthweight infants: evidence from New Zealand national population based data
    B A Darlow
    Department of Paediatrics, Christchurch School of Medicine, New Zealand
    Arch Dis Child Fetal Neonatal Ed 88:F23-8. 2003
    ..To compare the survival and short term morbidity of all New Zealand very low birthweight (VLBW) infants born in two epochs, 1986 and 1998-1999...
  57. ncbi Neonatal candidiasis among extremely low birth weight infants: risk factors, mortality rates, and neurodevelopmental outcomes at 18 to 22 months
    Daniel K Benjamin
    Department of Pediatrics, Duke Clinical Research Institute, Duke University, Durham, North Carolina, USA
    Pediatrics 117:84-92. 2006
    ..Neonatal candidiasis is associated with substantial morbidity and mortality rates. Neurodevelopmental follow-up data for a large multicenter cohort have not been reported...
  58. ncbi Effects of infant risk status and maternal psychological distress on maternal-infant interactions during the first year of life
    Lynn T Singer
    Departments of Pediatrics and General Medical Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
    J Dev Behav Pediatr 24:233-41. 2003
    ..Because maternal distress is more prevalent in mothers of VLBW infants postpartum, intervention efforts should focus on assessment of maternal distress and the challenges posed by the interactive behaviors of VLBW infants...
  59. ncbi Low superior vena cava flow on day 1 and adverse outcome in the very low birthweight infant
    J Miletin
    Department of Paediatrics and Newborn Medicine, Coombe Women s Hospital, Dublin, Ireland
    Arch Dis Child Fetal Neonatal Ed 93:F368-71. 2008
    ..Superior vena cava (SVC) flow assesses blood flow from the upper body, and may provide a reliable assessment of systemic blood flow...
  60. ncbi Gender differences in neurodevelopmental outcomes among extremely preterm, extremely-low-birthweight infants
    Susan R Hintz
    Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA 94304, USA
    Acta Paediatr 95:1239-48. 2006
    ..To determine whether gender-specific responses to perinatal and neonatal events and exposures explain the male disadvantage in early childhood outcomes...
  61. ncbi Effects of a combined therapy of erythropoietin, iron, folate, and vitamin B12 on the transfusion requirements of extremely low birth weight infants
    Nadja Haiden
    Department of Pediatrics, Division of Neonatology and Intensive Care, Medical University of Vienna, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Pediatrics 118:2004-13. 2006
    ..The aim of this trial was to investigate whether combined administration of vitamin B12, folic acid, iron, and erythropoietin could decrease transfusion requirements in extremely low birth weight infants...
  62. pmc Health, lifestyle, and quality of life for young adults born very preterm
    R W I Cooke
    Neonatal Unit, Liverpool Women s Hospital, Crown Street, Liverpool L8 7SS, UK
    Arch Dis Child 89:201-6. 2004
    ..It is not clear whether these problems persist into adulthood, impacting on lifestyle and quality of life...
  63. pmc Smoking and hepatoblastoma: confounding by birth weight?
    L G Spector
    Br J Cancer 89:602; author reply 603. 2003
  64. ncbi Randomized placebo-controlled trial of a 42-day tapering course of dexamethasone to reduce the duration of ventilator dependency in very low birth weight infants: outcome of study participants at 1-year adjusted age
    T M O'Shea
    Department of Pediatrics, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Pediatrics 104:15-21. 1999
    ..The objective of this study was to assess the effect of this therapy on developmental outcome at 1 year of age...
  65. ncbi Early treatment with erythropoietin beta ameliorates anemia and reduces transfusion requirements in infants with birth weights below 1000 g
    Rolf F Maier
    J Pediatr 141:8-15. 2002
    ..To investigate whether recombinant erythropoietin (rhEPO) reduces the need for transfusion in extremely low birth weight (ELBW) infants (birth weight 500-999 g) and to determine the optimal time for treatment...
  66. ncbi The prevalence of socioeconomic and behavioral characteristics and their impact on very low birth weight in black and white infants in Georgia
    C J Berg
    Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, US Public Health Service, US Department of Health and Human Services, Atlanta, Georgia 30341, USA
    Matern Child Health J 5:75-84. 2001
    ..We examined possible reasons for the disparity in the rate of very low birth weight (VLBW) delivery (<1500 g) in the United States between black women and white women...
  67. pmc Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants
    Edward F Bell
    Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
    Pediatrics 115:1685-91. 2005
    ..The objective of this study was to determine if restrictive guidelines for red blood cell (RBC) transfusions for preterm infants can reduce the number of transfusions without adverse consequences...
  68. ncbi Case-control study of perinatal factors and hepatoblastoma in children with an extremely low birthweight
    K Maruyama
    Department of Neonatology, Gunma Children s Medical Center, Seta gun, Japan
    Pediatr Int 42:492-8. 2000
    ..There is a significant association between hepatoblastoma and low birthweight. A case-control study was conducted to reveal risk factors for hepatoblastoma in children of extremely low birthweight (< 1,000 g)...
  69. ncbi Diagnostic criteria and therapeutic interventions for the hypotensive very low birth weight infant
    E M Dempsey
    Department of Pediatrics, McGill University Health Center, Montreal Canada
    J Perinatol 26:677-81. 2006
    ..The diagnosis and management of hypotension in the very low birth weight (VLBW) is a controversial area...
  70. ncbi Timing of initial surfactant treatment for infants 23 to 29 weeks' gestation: is routine practice evidence based?
    Jeffrey D Horbar
    Department of Pediatrics, University of Vermont College of Medicine, Burlington, Vermont, USA
    Pediatrics 113:1593-602. 2004
    ..To describe the timing of initial surfactant treatment for high-risk preterm infants in routine practice and compare these findings with evidence from randomized trials and published guidelines...
  71. ncbi Erythropoietin and prematurity--where do we stand?
    Xavier Carbonell-Estrany
    Servicio de Neonatologia, Institut Clinic de Ginecologia, Obstetricia i Neonatologia, Hospital Clinic, Unidad integrada de Pediatria, IDIBAPS, Universidad de Barcelona, Barcelona, Spain
    J Perinat Med 33:277-86. 2005
    ..It should be started at 3-7 days of life at doses of 250 U/kg subcutaneously, three times a week, for 4-6 weeks depending on gestational age with oral iron 2-12 mg/kg/day to keep ferritin levels greater than 100 ng/mL...
  72. ncbi Urinary bladder perforation in a very low birth weight infant. A case report
    Husam Salama
    Department of Pediatrics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    J Perinat Med 30:188-91. 2002
    ....
  73. ncbi Neurodevelopmental outcome and growth at 18 to 22 months' corrected age in extremely low birth weight infants treated with early erythropoietin and iron
    Robin K Ohls
    Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
    Pediatrics 114:1287-91. 2004
    ..Clinical trials evaluating the use of erythropoietin (Epo) have demonstrated a limited reduction in transfusions; however, long-term developmental follow-up data are scarce...
  74. ncbi Breakthrough candida Infection in a preterm infant with congenital cutaneous Candida albicans infection
    Amos Adler
    Department of Neonatology, Meir Medical Center, Kfar Saba 95847, Israel
    Am J Perinatol 22:169-72. 2005
    ..We discuss the pathogenesis of breakthrough infections, and the relevance of antifungal resistance and sensitivities testing...
  75. ncbi Mortality for newborns of birthweight less than 1500 g in Spanish neonatal units (2002-2005)
    Manuel Moro
    Servicio de Neonatologia, Hospital Clinico San Carlos, Madrid, Spain
    Am J Perinatol 24:593-601. 2007
    ..Our findings highlight the need to promote intrauterine transport and improve neonatal transport as well as the management of these infants in the delivery room and within the first 28 days of life...
  76. ncbi Neonatal sepsis in very low birthweight infants at the University Hospital of the West indies
    H Trotman
    Department of Obstetrics, Gynaecology and Child Health, The University of the West Indies, Kingston 7, Jamaica, West Indies
    West Indian Med J 55:165-9. 2006
    ....
  77. ncbi The NICHD neonatal research network: changes in practice and outcomes during the first 15 years
    Avroy A Fanaroff
    Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Semin Perinatol 27:281-7. 2003
    ..Advances in perinatal care within NICHD Network centers have resulted in marked improvements in survival. Further advances are required to increase survival free of neonatal morbidity or neurodevelopmental impairment...
  78. ncbi Data collection from very low birthweight infants in a geographical region: methods, costs, and trends in mortality, admission rates, and resource utilisation over a five-year period
    J Dorling
    Department of Health Sciences, University of Leicester, LE2 7LX, UK
    Early Hum Dev 82:117-24. 2006
    ..2. To demonstrate a cost-effective method of regional data collection. 3. To determine whether there were any changes in the demand for neonatal care...
  79. ncbi Heart rate characteristics and laboratory tests in neonatal sepsis
    M Pamela Griffin
    Department of Pediatrics, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Pediatrics 115:937-41. 2005
    ..The objective of this study was to test the hypothesis that HRC monitoring adds information to conventional laboratory tests in diagnosing neonatal sepsis...
  80. doi The umbilical arterial catheter: a formula for improved positioning in the very low birth weight infant
    Ian M R Wright
    Kaleidoscope Neonatal Intensive Care Unit, John Hunter Children s Hospital, New South Wales, Australia
    Pediatr Crit Care Med 9:498-501. 2008
    ..Our hypothesis was that the new formula would improve the siting of umbilical arterial catheters in very low birth weight infants...
  81. ncbi Infant, mother, and contextual predictors of mother-very low birth weight infant interaction at 9 months of age
    Nancy Feeley
    Centre for Nursing Research, S M B D Jewish General Hospital, 3755 Cote St Catherine Road, Montreal, Quebec, Canada H3T 1E2
    J Dev Behav Pediatr 26:24-33. 2005
    ..The findings highlight the importance of maternal education and well-being in the parenting of VLBW infants...
  82. ncbi Changes in perinatal care and survival in very preterm and extremely preterm infants in The Netherlands between 1983 and 1995
    Sabine Anthony
    Child Health Division, TNO Prevention and Health, PO Box 92215, 2301 CE Leiden, The Netherlands
    Eur J Obstet Gynecol Reprod Biol 112:170-7. 2004
    ..To evaluate changes in obstetrical and neonatal care for very preterm and extremely preterm infants between 1983 and 1995 in The Netherlands and to evaluate the effect of those changes...
  83. ncbi Neonatal cardiac vagal tone and school-age developmental outcome in very low birth weight infants
    J A Doussard-Roosevelt
    Institute for Child Study, University of Maryland College Park, MD 20742 1131, USA
    Dev Psychobiol 38:56-66. 2001
    ..Results support the hypothesis that early central nervous system self-regulatory abilities, as assessed by RSA measures, are predictive of later complex behaviors...
  84. ncbi Maternal and infant factors associated with excess kindergarten costs
    Jeffrey Roth
    Department of Pediatrics, University of Florida, PO Box 100296, Gainesville, FL 32610 0296, USA
    Pediatrics 114:720-8. 2004
    ..Projecting these costs from information that is available at birth can assist school districts and state agencies in allocating resources...
  85. ncbi Survival and outcome of very low birth weight infants born in a university hospital with level II NICU
    Suthida Sritipsukho
    Department of Pediatrics, Faculty of Medicine, Thammasat University Rangsit Campus, Patumthanee 12120, Thailand
    J Med Assoc Thai 90:1323-9. 2007
    ..Determine the survivals, neonatal outcomes to hospital discharge, and perinatal risks of death among VLBW infants born in the Thammasat University Hospital...
  86. ncbi Changes in mortality for extremely low birth weight infants in the 1990s: implications for treatment decisions and resource use
    William Meadow
    Department of Pediatrics and MacLean Center for Clinical Medical Ethics, University of Chicago, Chicago, Illinois, USA
    Pediatrics 113:1223-9. 2004
    ..We wondered how these medical advances had affected both the epidemiology and ethics of life and death for extremely low birth weight (ELBW) infants in the NICU...
  87. pmc The changes in the mortality rates of low birth weight infant and very low birth weight infant in Korea over the past 40 years
    Young Min Bae
    Department of Pediatrics, College of Medicine, Kyunghee University Hospital, 1 Hoiki Dong, Dongdamun gu, Seoul 130 702, Korea
    J Korean Med Sci 19:27-31. 2004
    ..2% in 1960, to 56.7% in 1970, to 50.8% in 1980, to 32.9% in 1990, and to 11.7% in 2000. The MR of LBWI and VLBWI has gone down remarkably due to improvements in neonatology in Korea as shown above...
  88. ncbi Fluconazole for prophylaxis against candidal rectal colonization in the very low birth weight infant
    S D Kicklighter
    Wake Medical Center, Raleigh, North Carolina 27620, USA
    Pediatrics 107:293-8. 2001
    ..Current intervention focuses on treatment once candidal septicemia is either suspected or diagnosed. Studies have suggested that colonization with candidal species is an important risk factor for subsequent infection...
  89. ncbi Patterns of colonization with Ureaplasma urealyticum during neonatal intensive care unit hospitalizations of very low birth weight infants and the development of chronic lung disease
    Susana Castro-Alcaraz
    Schneider Children s Hospital, North Shore Long Island Jewish Health System, Long Island, New York, USA
    Pediatrics 110:e45. 2002
    ....
  90. ncbi Surgical closure of patent ductus arteriosus in very-low-birth-weight infants
    H Niinikoski
    Department of Pediatrics, University of Turku, Finland
    Pediatr Surg Int 17:338-41. 2001
    ..The surgery-related mortality was 3% (3/101) and overall mortality 10% (10/101). We conclude that surgical closure of PDA is safe and effective in VLBW infants...
  91. ncbi Retinopathy of prematurity and other ocular problems in premature infants weighing less than 1500 g at birth
    I C Asproudis
    University Eye Clinic, University of Ioannina, Ioannina, Greece
    Eur J Ophthalmol 12:506-11. 2002
    ..To estimate the incidence of retinopathy of prematurity and other ocular problems in a population of preterm infants...
  92. ncbi Functional limitations and special health care needs of 10- to 14-year-old children weighing less than 750 grams at birth
    M Hack
    Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA
    Pediatrics 106:554-60. 2000
    ..To examine the health status, functioning, and special health care needs of children 10 to 14 years old weighing <750 g at birth...
  93. doi Weight gain measured at 6 weeks after birth as a predictor for severe retinopathy of prematurity: study with 317 very low birth weight preterm babies
    Joao Borges Fortes Filho
    Medical School, Department of Ophthalmology, Federal University of Rio Grande do Sul and Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil
    Graefes Arch Clin Exp Ophthalmol 247:831-6. 2009
    ..Recent studies suggest that postnatal weight gain can play an important role in the development of retinopathy of prematurity (ROP)...
  94. ncbi [Resuscitation in very low birth weight and extremely low birth weight newborns in the delivery room]
    L Vakrilova
    University Maternity Hospital Maichin Dom, Sofia, Bulgaria
    Akush Ginekol (Sofiia) 41:18-23. 2002
    ....
  95. ncbi Risk factors for nosocomial infections in a neonatal intensive-care unit
    C Auriti
    Division of Neonatal Intensive Care, Bambino Gesu Children s Hospital, Rome, Italy
    J Hosp Infect 53:25-30. 2003
    ..HAIs frequently complicate hospitalization in NICUs and are associated with increased mortality. Our findings also suggest that CRIB could be predictive for the risk of infection in VLBW infants...
  96. ncbi Collaborative quality improvement for neonatal intensive care. NIC/Q Project Investigators of the Vermont Oxford Network
    J D Horbar
    University of Vermont College of Medicine and Vermont Oxford Network, Burlington, Vermont, USA
    Pediatrics 107:14-22. 2001
    ..CONCLUSION: We conclude that multidisciplinary collaborative quality improvement has the potential to improve the outcomes of neonatal intensive care...
  97. ncbi A study of bone mineral density and physical growth in very low birth-weight infants after their discharge from hospital
    Chiharu Kanbe
    Department of Pediatrics, Yodogawa Christian Hospital, Osaka, Japan
    J Bone Miner Metab 20:106-10. 2002
    ....
  98. ncbi Growth and bone mineralization of young adults weighing less than 1500 g at birth
    H A Weiler
    Department of Foods and Nutrition, University of Manitoba, Winnipeg, Manitoba, Canada R3T 2N2
    Early Hum Dev 67:101-12. 2002
    ..Preterm infants are at risk for suboptimal growth and bone mineralization compared to infants born at term but long-term outcomes into early adulthood are unclear...
  99. ncbi School-age consequences of birth weight less than 750 g: a review and update
    H G Taylor
    Department of Pediatrics, Case Western Reserve University, Rainbow Babies and Children s Hospital of University Hospitals of Cleveland, USA
    Dev Neuropsychol 17:289-321. 2000
    ..Further research is needed to understand the etiology and neuropathological basis of sequelae, the long-term developmental implications of LBW, and treatment needs...
  100. ncbi Impact of erythromycin on respiratory colonization of Ureaplasma urealyticum and the development of chronic lung disease in extremely low birth weight infants
    E D Bowman
    Department of Pediatrics, The Royal Women s Hospital, Carlton, Victoria, Australia
    Pediatr Infect Dis J 17:615-20. 1998
    ..This study examines neonates colonized with U. urealyticum in the lower respiratory tract and treated with erythromycin, as compared with noncolonized neonates...
  101. ncbi Positive changes among very low birth weight infant Apgar scores that are associated with the Neonatal Resuscitation Program in Illinois
    Daksha Patel
    Saint Joseph Hospital, Resurrection Health Care and Northwestern University Medical School, Chicago, IL 60657, USA
    J Perinatol 22:386-90. 2002
    ..This study evaluated the hypothesis that the statewide NRP in Illinois hospitals was associated with positive outcomes in the Apgar scores among very low birth weight newborns...

Research Grants65

  1. Hybrid Optical/Doppler Imaging of Ischemia in NEC - a multicenter trial
    David A Benaron; Fiscal Year: 2010
    ..If successful, the health benefit will be large, as it is estimated that treating NEC alone (not including treating its later complications) adds $650 million to the annual health bill. ..
  2. Lactoferrin Enhances Growth and Reduces Nosocomial Infection in Preterm Infants
    Karel Petrak; Fiscal Year: 2009
    ..Marketing approval for TLF to treat NIs would be of great benefit to the patients and the community, and would also be of a substantial commercial value. ..
  3. Wireless At-Risk Infant Monitoring System
    JASON HOLMSTEDT; Fiscal Year: 2012
    ..PUBLIC HEALTH RELEVANCE: The proposed portable medical monitor system will offer a simple solution for measuring the vital health signs of at-risk newborn babies and can be used in neonatal intensive care units and home settings. ..
  4. Effect of Lactobacillus GG on gut permeability and microbiome in VLBW neonates
    ROSE MARIE VISCARDI; Fiscal Year: 2013
    ..The data generated from the proposed studies will directly lead to decisions concerning future randomized safety and efficacy trials of LGG to prevent NEC in the preterm population. ..
  5. Right Heart-Pulmonary Vascular Interactions in Bronchopulmonary Dysplasia
    Marlowe Eldridge; Fiscal Year: 2013
    ..We have a unique and important opportunity to investigate the consequences of BPD on lung and right heart function in this population, which will inform treatment strategies and predictions of disease progression in the future. ..
  6. GI-Safer Formulation of Indomethacin for use in Preterm Neonates
    UPENDRA K MARATHI; Fiscal Year: 2010
    ..This grant proposal will partially fund the development of a new molecular complex of indomethacin and phosphatidylcholine, a new formulation of indomethacin that significantly reduces GI injury. ..
  7. Biomarker Profiles for Early Diagnosis of Sepsis in Neonates
    JAMES PRESTON MAPES; Fiscal Year: 2011
    ....
  8. Routine Aspiration of Residual Gastric Contents in Very Low Birth Weight Infants
    Leslie A Parker; Fiscal Year: 2013
    ..Public Health Relevance: This research has potential to influence health policy and practices that may directly translate to improved nutritional and health outcomes for premature VLBW infants. ..
  9. Genetic Manipulation of Unreaplasma spp. Infecting Humans using Synthetic Genomic
    JOHN IRVIN GLASS; Fiscal Year: 2013
    ..Learning how to transplant ureaplasma genomes could lead to our being able to do this for many other species including bacteria with unrealized pharmaceutical or industrial potential, for which we have no genetic tools. ..
  10. Mother Sibling Interactions
    Julie A Thompson; Fiscal Year: 2010
    ..The proposed study is germane to the goal of identifying factors to promote the health of young children, particularly those who are at risk for maladjustment due to having a sibling with a chronic medical condition. ..
  11. Early Identification of Developmental Disorders in Infants
    B Eugene Parker; Fiscal Year: 2012
    ....
  12. PROTECTIVE EFFECTS OF DELAYED CORD CLAMPING IN VLBW INFANTS
    JUDITH SMITH MERCER; Fiscal Year: 2012
    ..If delaying cord clamping at the births of preterm infants lowers rates of intraventricular hemorrhage and late onset sepsis it may have a dramatic effect on the health and well being of these infants. ..
  13. Validation in Baboon Model of Broadband NIR Monitoring for Neonate Gut Perfusion
    David A Benaron; Fiscal Year: 2012
    ..Aim 3 - To determine the safety of probes used with the T-Stat Perfusion Monitor. ..
  14. Ophthalmologic Follow-up Care for Children Born Very-Low-Birth-Weight
    CHIHHUNG JASON WANG; Fiscal Year: 2012
    ..The findings will have important public health implications for tracking their health, development, and educational outcomes. ..
  15. Longitudinal Study of Dental Caries in VLBW Infants
    Suchitra S Nelson; Fiscal Year: 2013
    ..It is also of public health interest since interventions to target knowledge, attitude, beliefs, and oral health practices can be implemented in programs for special needs children, and there by improve both oral and systemic health. ..
  16. Effect of Air Pollution and Traffic on Birth Outcomes
    Michelle L Bell; Fiscal Year: 2012
    ..If confirmed, reductions in specific types of air pollution may reduce these major infant health problems. ..
  17. Multiple Chronic Conditions in VLBW Infants: Epidemiology, NICU Care, and Outcome
    William Gardner; Fiscal Year: 2010
    ..Because PVLBW babies are often subject to multiple chronic disorders and are over-represented in an underserved community, they are a priority population for comparative effectiveness research. ..
  18. Brain imaging and developmental follow-up of infants treated with erythropoietin
    Robin K Ohls; Fiscal Year: 2013
    ....
  19. Chronic intermittent hyperoxia and development of respiratory control
    Ryan W Bavis; Fiscal Year: 2013
    ..Undergraduate students will contribute to all aspects of the proposed research. Therefore, this project will also provide valuable training opportunities for talented students interested in biomedical research and medicine. ..
  20. Comprehensive Clinical Decision Support for the Primary Care of Premature Infants
    Robert W Grundmeier; Fiscal Year: 2010
    ....
  21. Noninvasive, Optoacoustic Monitoring of Cerebral Circulation in Preterm Neonates
    GRAHAM RANDALL; Fiscal Year: 2013
    ..Specific Aim 3. Preliminarily establish in vivo in neonates the range of SSSSO2 to be expected in infants of varying body weight (10-12 LBW neonates and 10-12 VLBW neonates). ..
  22. GENERAL CLINICAL RESEARCH CENTER
    William B Applegate; Fiscal Year: 2010
    ..abstract_text> ..
  23. APOE and Brain Injury in Premies
    James A Blackman; Fiscal Year: 2010
    ..If so, this could lead to a clinical trial of administration of an e4 protein isoform in the acute setting. Success in such a trial could provide a radically new and innovative approach to acute treatment of BI in newborns. ..
  24. Epigenetic Programming of Metabolic Flexibility
    Lyda Williams; Fiscal Year: 2013
    ..Our studies may encourage pregnant women to change their lifestyle and result in more healthful pregnancies. ..
  25. Development of Monoclonal Antibody (Mab) Biologics against Neonatal Candidiasis
    Jose L Lopez-Ribot; Fiscal Year: 2013
    ....
  26. Accelerating Adoption of Comparative Effectiveness Research in Premature Infants
    Phillip Brian Smith; Fiscal Year: 2010
    ....
  27. Analysis of a collaborative worldwide network of neonatal ICU's
    JEFFREY DAVID HORBAR; Fiscal Year: 2012
    ..The methods and results from the proposed work will have widespread application to managing collaborative health care networks that seek to innovate and spread quality improvement practices between hospitals around the world. ..
  28. Chemical Exposures and Infant Outcomes in the Neonatal Intensive Care Unit
    Annemarie Stroustrup; Fiscal Year: 2013
    ..In this study, the candidate will evaluate the relationship between chemical exposure in the NICU and infant medical and neurobehavioral outcomes. ..
  29. Effects of Fine Particle Composition on Birth Outcomes
    Michelle L Bell; Fiscal Year: 2013
    ..Findings from this study will identify the components or sources of PM2.5 with the greatest impact on birth outcomes and could lead to interventions targeted at the sources most toxic to infant health. ..
  30. Adequate Breast Milk for Improved Health of Very Low Birth Weight Preterm Infants
    Leslie A Parker; Fiscal Year: 2013
    ..Public Health Relevance: This research has potential to influence health policy and practices that may directly translate to increased breast milk production and better health outcomes for VLBW infants. ..
  31. Service Delivery Models to Reduce Maternal and Child Health Disparities
    Sharon Landesman Ramey; Fiscal Year: 2011
    ..Overall, we seek to create a partnership that will promote both receptivity to new knowledge (research findings) and innovation in community service delivery and research on service delivery. ..
  32. NICU-2-HOME: Using HIT to support parents of NICU graduates transitioning home
    Craig F Garfield; Fiscal Year: 2012
    ..Data and experience gained from this project will inform a possible AHRQ R18 to support a multi-center intervention. ..
  33. Novel Mechanisms and Approaches to Treat Neonatal Sepsis
    Lyle L Moldawer; Fiscal Year: 2013
    ..Studies are proposed to examine differential adaptor signaling in murine neonatal sepsis, and explore the use of adjuvants that will enhance survival. ..
  34. Causal Mediation Analysis of Dental Caries in VLBW and BPD Adolescents
    Jeffrey M Albert; Fiscal Year: 2010
    ..By understanding the mechanisms leading to dental caries in VLBW/BPD children, we can more effectively intervene to improve the oral and general health of these special needs children. ..
  35. The Effects of Nursing on NICU Patient Outcomes
    Jeannette A Rogowski; Fiscal Year: 2011
    ..The project will also provide new knowledge on the potential role of nursing in explaining and addressing observed disparities in infant outcomes for VLBW infants treated in minority-serving hospitals. ..
  36. ESTABLISHMENT AND DYNAMICS OF ANTIBIOTIC RESISTANCE RESERVOIRS IN DEVELOPING INTE
    Gautam Dantas; Fiscal Year: 2013
    ....
  37. Noninvasive Optoacoustic Monitoring of Intrapartum Fetal Cerebral Hypoxia
    GRAHAM RANDALL; Fiscal Year: 2013
    ..After implementation of the proposed project, we will build and test a manufacturing-ready prototype and secure 510k clearance from the FDA. ..
  38. Gastrointestinal Risk Factors for Wheezing in Premature Infants
    Anna Maria Hibbs; Fiscal Year: 2011
    ..This study will facilitate the design of future trials of therapies to prevent wheezing by identifying targetable risk factors and appropriate non-invasive measurement tools. ..
  39. Do Obstetrical Quality Measures Explain Racial Disparities in Perinatal Outcomes
    Elizabeth A Howell; Fiscal Year: 2013
    ....
  40. GABA-mediated connectivity in the preterm brain
    Laura R Ment; Fiscal Year: 2012
    ..These data will provide critical information about the impact of preterm birth on the developing brain and offer fundamental insights into prevention of handicap in the prematurely born. ..
  41. Early H-1 brain injury and behavioral outcome in rats
    ROSLYN FITCH; Fiscal Year: 2009
    ..Future applications may include improvements in cognitive outcome predictions following HI injury, as well as increased insight on amelioration treatment and therapy for infants suffering early HI injuries. ..
  42. Development of Neural Systems Underlying Learning and Response to Novelty
    Dima Amso; Fiscal Year: 2012
    ..The K01 studies will provide a means by which interpretations of data from future clinical studies can be constrained. ..
  43. Eunice Kennedy Shriver NICHD Cooperative Multicenter Neonatal Research Network
    Barbara J Stoll; Fiscal Year: 2013
    ..Dr. Stoll and our entire Neonatal Division are enthusiastic in their commitment to the NRN. PUBLIC HEALTH RELEVANCE (See instructions): ..
  44. MULTICENTER NETWORK OF NEONATAL INTENSIVE CARE UNITS
    T O SHEA; Fiscal Year: 2005
    ..abstract_text> ..
  45. Training Program in Genome-Environment Interactions in Neonatal Disease
    George Scott Worthen; Fiscal Year: 2013
    ....
  46. Geographic modeling of very low birth weights around and near Texas federal super
    James A Thompson; Fiscal Year: 2010
    ..These advances include both Multivariate and hierarchical modeling. The results will be crucial for designing and justifying the locations and diseases to evaluate in a forthcoming application. ..
  47. A Neonatal Cerebral Blood Flow Monitor based on MEMS Ultrasound
    DAVID FREDERICK LEMMERHIRT; Fiscal Year: 2012
    ..This would clearly have immense human benefit and would also reduce healthcare spending, given recent estimates that suggest the lifetime cost of care for each cerebral palsy patient will exceed $1M. ..
  48. Early Identification of Developmental Disorders in Infants
    B Parker; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  49. The Effects of Neonatal Intensive Care Deregionalization on Treatment and Infant
    SETH FREEDMAN; Fiscal Year: 2009
    ..Understanding these effects is necessary to fully evaluate the public health consequences of the increased availability of this type of care. ..
  50. VITAMIN B2 AND B6 IN VERY LOW BIRTH WEIGHT INFANTS
    LARRY SWIFT; Fiscal Year: 1992
    ....
  51. Generalized Causal Mediation Analysis for Social Environment and Health Research
    Jeffrey M Albert; Fiscal Year: 2013
    ..They will also facilitate the formulation of effective behavioral and other interventions, utilizing knowledge about social environment mechanisms, to improve health outcomes. ..
  52. Novel Complementary Therapy for Preterm Infants
    John Bauer; Fiscal Year: 2009
    ..We will carry out preclinical studies to define mechanistic actions and identify optimal conditions for potential efficacy using relevant human fetal intestinal epithelial cells and animal models of newborn intestinal injury. ..
  53. Recombinant Lactoferrin and Necrotizing Enterocolitis
    Karel Petrak; Fiscal Year: 2004
    ..The data generated by this research are essential for the FDA to grant Investigational New Drug [IND] status for rhLF, and thus enable a NEC clinical trial in human neonates. ..
  54. Plurality and Contemporary Infant Mortality Risks
    Barbara Luke; Fiscal Year: 2006
    ..abstract_text> ..
  55. Oral Health Problems of BPD and VLBW adolescents
    Suchitra Nelson; Fiscal Year: 2005
    ..It is also of public health interest since interventions to target attitudes and oral health practices can be implemented in programs for special health needs children, and there by be useful for improving both oral and general health. ..
  56. Parenteral Medium Chain Triglycerides in the Premature
    Eberhard Schmidt Sommerfeld; Fiscal Year: 2002
    ..The long term goal is to determine whether the addition of MCT and L-carnitine to TPN will improve the nutrition of premature infants during a critical period of their lives. ..
  57. Regulation of Glucose Metabolism in Extremely Low Birth Weight (ELBW) Infants
    AGNETA LISBETH SUNEHAG; Fiscal Year: 2010
    ..A clear understanding of the mechanisms that control glucose homeostasis in the extremely low birth weight infant will permit us to develop evidence based strategies to maintain euglycemia while providing appropriate energy intake. ..
  58. Center for Patient Safety in Neonatal Intensive Care
    Jeffrey Horbar; Fiscal Year: 2003
    ..abstract_text> ..
  59. Models of Birthweight and Low Birthweight
    Narayan Sastry; Fiscal Year: 2004
    ..The first is the 1997 Natality Data Set (NDS), compiled from birth certificates by the National Center for Health Statistics. The second data source is the 1988 National Maternal and Infant Health Survey (NMIHS). ..
  60. The Economics of Mother's Milk Feedings in Neonatal Intensive Care Unit
    Briana Jegier; Fiscal Year: 2006
    ..Finally, it will show mothers and providers the dose of milk that needs to be achieved in order to gain maximum economic benefit and the resources that are needed to achieve that dose. [unreadable] [unreadable]..
  61. THE EFFECTS OF RURAL OBSTETRIC CARE PROVIDER SHORTAGES
    Wayne Ray; Fiscal Year: 1992
    ..These risk factors include: maternal life style (e.g., cigarette smoking), maternal medical problems (e.g., anemia), complications of labor and delivery, transport of mother and infant, and newborn complications...
  62. VITAMIN A THERAPY IN PRETERM INFANTS: VACCINE RESPONSE
    Mark Ballow; Fiscal Year: 2002
    ..These factors could lead to decreased morbidity and mortality of pre-term infants during early postnatal life. ..
  63. Non-Contact Monitor for Infants at Risk
    DAVID GERDT; Fiscal Year: 2005
    ..The objective of this work is to eliminate or augment ECG electrodes both in the NICU and the home for the important clinical exercise of close monitoring of infants at risk. ..
  64. Postpartum Depressive Symptoms: A Search for a Biologic Marker
    LINDSEY GARFIELD; Fiscal Year: 2010
    ..This will benefit up to 50% of mothers with this condition that are not currently diagnosed. ..
  65. |
    John Widness; Fiscal Year: 1991
    ..Information related to neonatal anemia and erythropoiesis is important in understanding which neonates will benefit from treatment with blood transfusion, rhEp, or with a combination of the two...