influenzavirus a

Summary

Summary: A genus in the family ORTHOMYXOVIRIDAE causing influenza and other diseases in humans and animals. It contains many strains as well as antigenic subtypes of the integral membrane proteins hemagglutinin (HEMAGGLUTININS) and NEURAMINIDASE. The type species is INFLUENZA A VIRUS.

Top Publications

  1. ncbi [Effectiveness of oseltamivir treatment against influenza type A and type B infection in children]
    Keiko Mitamura
    Department of Pediatrics, Nippon Kokan Hospital
    Kansenshogaku Zasshi 76:946-52. 2002
  2. ncbi An overview of the epidemiology of avian influenza
    Dennis J Alexander
    Virology Department, VLA Weybridge, Addlestone, Surrey, UK
    Vaccine 25:5637-44. 2007
  3. ncbi [Outbreaks due to respiratory syncytial virus and influenzavirus A/H3N in institutionalized aged. Role of immunological status to influenza vaccine and possible implication of caregivers in the transmission]
    N Ruel
    Service de Gerontologie Clinique, Hôpital de la Charité, CHU de Saint Etienne, F42055 Saint Etienne
    Presse Med 31:349-55. 2002
  4. ncbi [Impact of rapid influenza test during influenza epidemic in all febrile children less than 6 years old in a pediatric emergency department]
    S Pierron
    Service de Pediatrie, Hôpital L Archet 2, CHU de Nice, 151 route de Saint Antoine de Ginestiere, 06202 Nice, France
    Arch Pediatr 15:1283-8. 2008
  5. ncbi Use of Oseltamivir to control influenza complications after bone marrow transplantation
    C M Machado
    Virology Laboratory LIM 52 HCFMUSP of the Instituto de Medicina Tropical de São Paulo, Sao Paulo, Brazil
    Bone Marrow Transplant 34:111-4. 2004
  6. ncbi Influenza virus infections in Yangon, Myanmar
    Go Hasegawa
    J Clin Virol 37:233-4. 2006
  7. ncbi Local surveillance of influenza in the United Kingdom: from sentinel general practices to sentinel cities?
    C M Regan
    Department of Public Health, Liverpool Health Authority
    Commun Dis Public Health 5:17-22. 2002
  8. pmc Influenza virus mRNA translation revisited: is the eIF4E cap-binding factor required for viral mRNA translation?
    Idoia Burgui
    Centro Nacional de Biotecnologia, CSIC Cantoblanco, 28049, Madrid, Spain
    J Virol 81:12427-38. 2007
  9. ncbi In vivo antiviral activity: defective interfering virus protects better against virulent Influenza A virus than avirulent virus
    Nigel J Dimmock
    Department of Biological Sciences, University of Warwick, Coventry, UK
    J Gen Virol 87:1259-65. 2006
  10. ncbi Activation of the antiviral prodrug oseltamivir is impaired by two newly identified carboxylesterase 1 variants
    Hao Jie Zhu
    Department of Pharmaceutical and Biomedical Sciences, Laboratory of Drug Disposition and Pharmacogenetics, Charles P Darby Children s Research Institute, Room 405B, Medical University of South Carolina, Charleston, SC 29425, USA
    Drug Metab Dispos 37:264-7. 2009

Scientific Experts

Detail Information

Publications108 found, 100 shown here

  1. ncbi [Effectiveness of oseltamivir treatment against influenza type A and type B infection in children]
    Keiko Mitamura
    Department of Pediatrics, Nippon Kokan Hospital
    Kansenshogaku Zasshi 76:946-52. 2002
    ..No differences in the effectiveness of oseltamivir treatment were observed between young children (< 4 years of age) and school-aged children (> 6 years of age). No obvious side effects were observed...
  2. ncbi An overview of the epidemiology of avian influenza
    Dennis J Alexander
    Virology Department, VLA Weybridge, Addlestone, Surrey, UK
    Vaccine 25:5637-44. 2007
    Only viruses of the Influenzavirus A genus have been isolated from birds and termed avian influenza [AI] viruses, but viruses with all 16 haemagglutinin [H1-H16] and all 9 neuraminidase [N1-N9] influenza A subtypes in the majority of ..
  3. ncbi [Outbreaks due to respiratory syncytial virus and influenzavirus A/H3N in institutionalized aged. Role of immunological status to influenza vaccine and possible implication of caregivers in the transmission]
    N Ruel
    Service de Gerontologie Clinique, Hôpital de la Charité, CHU de Saint Etienne, F42055 Saint Etienne
    Presse Med 31:349-55. 2002
    ....
  4. ncbi [Impact of rapid influenza test during influenza epidemic in all febrile children less than 6 years old in a pediatric emergency department]
    S Pierron
    Service de Pediatrie, Hôpital L Archet 2, CHU de Nice, 151 route de Saint Antoine de Ginestiere, 06202 Nice, France
    Arch Pediatr 15:1283-8. 2008
    ..To determine the impact of rapid influenza test (RIT) on the prescription of additional tests, antibiotics and oseltamivir, and the influence of oseltamivir on clinical signs and parents' day work stoppage...
  5. ncbi Use of Oseltamivir to control influenza complications after bone marrow transplantation
    C M Machado
    Virology Laboratory LIM 52 HCFMUSP of the Instituto de Medicina Tropical de São Paulo, Sao Paulo, Brazil
    Bone Marrow Transplant 34:111-4. 2004
    ..The therapeutic and/or prophylactic benefits of Oseltamivir in BMT recipients remain to be demonstrated in randomized, prospective trials...
  6. ncbi Influenza virus infections in Yangon, Myanmar
    Go Hasegawa
    J Clin Virol 37:233-4. 2006
  7. ncbi Local surveillance of influenza in the United Kingdom: from sentinel general practices to sentinel cities?
    C M Regan
    Department of Public Health, Liverpool Health Authority
    Commun Dis Public Health 5:17-22. 2002
    ....
  8. pmc Influenza virus mRNA translation revisited: is the eIF4E cap-binding factor required for viral mRNA translation?
    Idoia Burgui
    Centro Nacional de Biotecnologia, CSIC Cantoblanco, 28049, Madrid, Spain
    J Virol 81:12427-38. 2007
    ..The data reported are in agreement with a role of viral polymerase as a substitute for the eIF4E factor for viral mRNA translation...
  9. ncbi In vivo antiviral activity: defective interfering virus protects better against virulent Influenza A virus than avirulent virus
    Nigel J Dimmock
    Department of Biological Sciences, University of Warwick, Coventry, UK
    J Gen Virol 87:1259-65. 2006
    ..Thus, counter-intuitively, DI virus is most effective against viruses that cause disease with low numbers of particles, i.e. virulent viruses...
  10. ncbi Activation of the antiviral prodrug oseltamivir is impaired by two newly identified carboxylesterase 1 variants
    Hao Jie Zhu
    Department of Pharmaceutical and Biomedical Sciences, Laboratory of Drug Disposition and Pharmacogenetics, Charles P Darby Children s Research Institute, Room 405B, Medical University of South Carolina, Charleston, SC 29425, USA
    Drug Metab Dispos 37:264-7. 2009
    Oseltamivir phosphate is an ethyl ester prodrug widely used in the treatment and prevention of both Influenzavirus A and B infections...
  11. ncbi A common pathway mediated through Toll-like receptors leads to T- and natural killer-cell immunosuppression
    Ilan Vaknin
    Lautenberg Center for General and Tumor Immunology, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Blood 111:1437-47. 2008
    ..Thus, although acute TLR-mediated activation could be beneficial in clearing pathogens or may serve as an immune adjuvant, such activation could be detrimental under sustained conditions...
  12. ncbi [Review on replication cycle of influenza virus]
    Takehiko Saito
    Research Team for Zoonotic Diseases, Zoonotic Diseases Collaboration Center, National Institute of Animal Health, National Agriculture and Food Research Organization
    Nihon Rinsho 64:1803-7. 2006
    ..In this article, recent findings of the virus replication steps, particularly emphasized on receptor recognition, fusion process, RNP transport and assembly were reviewed...
  13. ncbi Influenzavirus infection is a primary cause of febrile respiratory illness in HIV-infected adults, despite vaccination
    Marina B Klein
    Department of Medicine, Division of Infectious Diseases, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    Clin Infect Dis 45:234-40. 2007
    ..We performed a surveillance study of outpatients who presented with fever and respiratory symptoms to examine the role of viral pathogens in these patients...
  14. ncbi [Influenza in Poland in 2006]
    Mirosław P Czarkowski
    Zakład Epidemiologii, Narodowy Instytut Zdrowia Publicznego PZH, ul Chocimska 24, 00 791 Warszawa
    Przegl Epidemiol 62:235-40. 2008
    ..All of these isolates with the exception of one strain of influenza B were antigenically similar to the vaccine strains recommended for the epidemic season 2005/06...
  15. ncbi Clinical effectiveness of first and repeat influenza vaccination in adult and elderly diabetic patients
    Ingrid Looijmans-Van den Akker
    Julius Center for Health Sciences and Primary Health Care, University Medical Center, Utrecht, The Netherlands
    Diabetes Care 29:1771-6. 2006
    ..We assessed the clinical effectiveness of influenza vaccination in adults with diabetes and specifically examined potential modification of effect by age and prior influenza vaccine uptake...
  16. ncbi Effectiveness of oseltamivir treatment among children with influenza A or B virus infections during four successive winters in Niigata City, Japan
    Maki Sato
    Department of Public Health, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
    Tohoku J Exp Med 214:113-20. 2008
    ..Our data provide evidence that oseltamivir is beneficial for influenza infections, but the effectiveness is differed by type and age...
  17. pmc Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling
    Benjamin G Hale
    Centre for Biomolecular Sciences, University of St Andrews, St Andrews, Fife KY16 9ST, United Kingdom
    Proc Natl Acad Sci U S A 103:14194-9. 2006
    ..These data suggest that activation of PI3K signaling in influenza A virus-infected cells is important for efficient virus replication...
  18. ncbi [Two cases of successfully treated invasive pulmonary aspergillosis following influenza virus infection]
    Tsukasa Ohnishi
    The First Department of Internal Medicine, Showa University Hospital
    Nihon Kokyuki Gakkai Zasshi 45:349-55. 2007
    ..A viral test showed a titre of 1/128 to influenza B. IPA must be considered for the differential diagnosis of complications of influenza virus infection...
  19. ncbi Molecular design of spacer-N-linked sialoglycopolypeptide as polymeric inhibitors against influenza virus infection
    Makoto Ogata
    Department of Bioscience, Graduate School of Science and Technology, Shizuoka University, Ohya 836, Suruga Ward, Shizuoka 422 8529, Japan
    Biomacromolecules 10:1894-903. 2009
    ....
  20. ncbi Oral administration of patchouli alcohol isolated from Pogostemonis Herba augments protection against influenza viral infection in mice
    Yu Cui Li
    College of Chinese Medicines, Guangzhou University of Chinese Medicine, Guangzhou, PR China
    Int Immunopharmacol 12:294-301. 2012
    ..Thus, oral administration of PA appears to be able to augment protection against IFV infection in mice via enhancement of host immune responses, and attenuation of systemic and pulmonary inflammatory responses...
  21. pmc Temporal and spatial resolution of type I and III interferon responses in vivo
    Julia Elisabeth Pulverer
    Department of Gene Regulation and Differentiation, Helmholtz Centre for Infection Research, Braunschweig, Germany
    J Virol 84:8626-38. 2010
    ....
  22. ncbi Absence of SP-A modulates innate and adaptive defense responses to pulmonary influenza infection
    Ann Marie LeVine
    Division of Pulmonary Biology, Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Am J Physiol Lung Cell Mol Physiol 282:L563-72. 2002
    ..Because the airway is the usual portal of entry for IAV and other respiratory pathogens, SP-A is likely to play a role in innate defense and adaptive immune responses to IAV...
  23. pmc Complete genome sequence of an H10N5 avian influenza virus isolated from pigs in central China
    Nan Wang
    Unit of Animal Infectious Disease, National State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, People s Republic of China
    J Virol 86:13865-6. 2012
    ..To our knowledge, this is the first report of interspecies transmission of an avian H10N5 influenza virus to domestic pigs under natural conditions...
  24. ncbi NK cells exacerbate the pathology of influenza virus infection in mice
    Gang Zhou
    Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada
    Eur J Immunol 43:929-38. 2013
    ..Our results indicate that during severe influenza infection of the lung, NK cells have a deleterious impact on the host, promoting mortality...
  25. ncbi [New antiviral agents of influenza]
    Makoto Miki
    Department of Respiratory Medicine, Japanese Red Cross Sendai Hospital
    Nihon Rinsho 70:649-54. 2012
    ....
  26. pmc DNA vaccine expressing conserved influenza virus proteins protective against H5N1 challenge infection in mice
    Suzanne L Epstein
    Food and Drug Administration, Rockville, Maryland 20852 1448, USA
    Emerg Infect Dis 8:796-801. 2002
    ..In the absence of antigenically matched hemagglutinin-based vaccines, DNA vaccination with conserved influenza genes may provide a useful first line of defense against a rapidly spreading pandemic virus...
  27. ncbi [Influenza in Poland in 2009]
    Mirosław P Czarkowski
    Zaklad Epidemiologii Narodowego Instytutu Zdrowia Publicznego Państwowego Zakładu Higieny w Warszawie
    Przegl Epidemiol 65:199-203. 2011
    ..83% all cases). According to Central Statistical Office data, there were 87 death cases, including 8 (9.2%) children in the age of 15. 70.1% of deaths were registered as cases caused by identified influenza virus...
  28. ncbi Production of influenza pseudotyped lentiviral particles and their use in influenza research and diagnosis: an update
    Jean Michel Garcia
    HKU Pasteur Research Centre, Dexter HC Man Building, 8 Sassoon Road, Pokfulam, Hong Kong
    Expert Rev Anti Infect Ther 9:443-55. 2011
    ..The second part focuses on the applications that such a flexible tool can provide in modern influenza research, in particular in the fields of drug discovery, molecular biology and diagnosis...
  29. pmc Identification of the 3' and 5' terminal sequences of the 8 rna genome segments of European and North American genotypes of infectious salmon anemia virus (an orthomyxovirus) and evidence for quasispecies based on the non-coding sequences of transcripts
    Vikas Kulshreshtha
    Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PEI, C1A 4P3, Canada
    Virol J 7:338. 2010
    ..Although the terminal sequences of other members of the family Orthomyxoviridae such as Influenzavirus A have been extensively analyzed, those of Isavirus remain largely unknown, and the few reported are from ..
  30. pmc The modes of evolutionary emergence of primal and late pandemic influenza virus strains from viral reservoir in animals: an interdisciplinary analysis
    Dany Shoham
    The Begin Sadat Center for Strategic Studies, Bar Ilan University, Ramat Gan 52900, Israel
    Influenza Res Treat 2011:861792. 2011
    ..conjunction with earliest chronologies pertaining to evolutionary emergences of ancestral RNA viruses, ducks, Influenzavirus A (assumingly within ducks), and hominids, as well as to the initial domestication of mallard duck (Anas ..
  31. pmc Avidity of influenza-specific memory CD8+ T-cell populations decays over time compromising antiviral immunity
    Ian R Humphreys
    Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK
    Eur J Immunol 42:3235-42. 2012
    ..These data imply that high-avidity central memory T cells wane with declining antigen levels, leaving lower avidity T cells with reduced functional capabilities...
  32. ncbi Utility of Maoto in an influenza season where reduced effectiveness of oseltamivir was observed - a clinical, non-randomized study in children
    Yoshitaka Toriumi
    Department of Pediatrics, Ohmura Hospital, Chiba, Japan
    Forsch Komplementmed 19:179-86. 2012
    ..In an influenza season where reduced effectiveness of oseltamivir was observed, we investigated the effectiveness of Maoto for influenza infection in children...
  33. ncbi [Expression of NA of influenza virus and C3d fusion gene in replication-defective recombinant adenovirus and its immune efficacy analysis]
    Feng Han
    Chinese Center for Disease Control and Prevention, Beijing, China
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 27:5-7. 2013
    ..To construct a replication-defective recombinant adenovirus expressing the fusion gene of neuraminidase (NA) gene in influenza virus A/FM/1/47 and C3d and to evaluate the induced immune efficacy...
  34. ncbi Co-infections with influenza and other respiratory viruses
    I Stefańska
    Department of Influenza Research, National Influenza Center, National Institute of Public Health National Institute of Hygiene, Warsaw, Poland
    Adv Exp Med Biol 756:291-301. 2013
    ....
  35. pmc Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection
    Christopher Lupfer
    Department of Immunology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Nat Immunol 14:480-8. 2013
    ..These results demonstrate a role for NOD2-RIPK2 signaling in protection against virally triggered immunopathology by negatively regulating activation of the NLRP3 inflammasome and production of IL-18 via ULK1-dependent mitophagy...
  36. ncbi [Screening for antibodies against zoonotic agents among employees of the Zoological Garden of Vienna, Schönbrunn, Austria]
    Martina Juncker-Voss
    Institut für Parasitologie und Zoologie, Department für Pathobiologie, Veterinärmedizinische Universität Wien
    Berl Munch Tierarztl Wochenschr 117:404-9. 2004
    ..The following seroprevalences (in brackets) were obtained: Viral zoonotic (and potentially zoonotic) agents: Influenzavirus A/H1N1 (58%), Influenzavirus A/H3N2 (85%), Lymphocytic choriomeningitis virus (13%), Encephalomyocarditis virus ..
  37. ncbi Optimized detection of respiratory viruses in nasopharyngeal secretions
    M Zavattoni
    Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy
    New Microbiol 26:133-40. 2003
    ..A pool of monoclonal antibodies (MAbs) to influenzavirus A and B, parainfluenzavirus types 1 to 3, adenoviruses and respiratory syncytial virus (RSV), as well as single ..
  38. ncbi Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis
    Michael T Osterholm
    Center for Infectious Disease Research and Policy, University of Minnesota, MN 55455, USA
    Lancet Infect Dis 12:36-44. 2012
    ..No published meta-analyses have assessed efficacy and effectiveness of licensed influenza vaccines in the USA with sensitive and highly specific diagnostic tests to confirm influenza...
  39. ncbi In vitro inhibition of influenza virus infection by a crude extract from Isatis indigotica root resulting in the prevention of viral attachment
    Zifeng Yang
    Clinical Virology Division, State Key Laboratory of Respiratory Diseases, Guangzhou Medical College, First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, PR China
    Mol Med Rep 5:793-9. 2012
    ..Thus, G2 may affect the attachment of influenza virus by interfering with the viral particles, thereby preventing the binding of influenza virus to the host cell surface...
  40. ncbi [Influence of four parts of forming of Yiqi Qingwen Jidu Heji (YQQWJDHJ) to lung inflammatory cytokines of model rats infected with influenza virus FM1]
    Hongri Xu
    Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China
    Zhongguo Zhong Yao Za Zhi 36:2703-9. 2011
    ....
  41. ncbi Gaseous nitric oxide reduces influenza infectivity in vitro
    Gilly Regev-Shoshani
    Department of Respiratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Nitric Oxide 31:48-53. 2013
    ..Viral NA inhibition by gNO was shown and may be responsible for this antiviral effect...
  42. pmc Longitudinal analysis of tetanus- and influenza-specific IgG antibodies in myeloma patients
    Sebastian Kobold
    Department of Internal Medicine II, and Department of Oncology, Hematology, Bone Marrow Transplantation Section of Pneumology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    Clin Dev Immunol 2012:134081. 2012
    ..We have performed a longitudinal analysis of IgG-antibody responses against influenza virus (FLU) and tetanus toxoid (TT) as surrogate markers for the B cell-mediated immunity in MM patients...
  43. ncbi [Establishment of drug screening assay and pharmacodynamic evaluation method targeting influenza RNA polymerase]
    Zhen Wang
    Department of lmmunology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Yao Xue Xue Bao 47:1159-63. 2012
    ..Specificity study and statistic analysis showed that the screening assay is sensitive and reproducible...
  44. ncbi Physicochemical and immunological characterization of N,N,N-trimethyl chitosan-coated whole inactivated influenza virus vaccine for intranasal administration
    Niels Hagenaars
    Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
    Pharm Res 26:1353-64. 2009
    ..The purpose of this study was the development and physicochemical and immunological characterization of intranasal (i.n.) vaccine formulations of whole inactivated influenza virus (WIV) coated with N,N,N-trimethyl chitosan (TMC)...
  45. ncbi [The origin of the genetic variability of influenza viruses]
    Ma Isabel Salazar
    Departamento de Inmunologia, Genética Instituto Politécnico Nacional, Mexico, DF Mexico
    Gac Med Mex 146:199-206. 2010
    ..These two combined mechanisms confer a genetic plasticity that often leads to the emergence of new influenza viruses in nature...
  46. ncbi [Effects of Yinqiao detoxifcation oral liquid on NK cell viability and serum concentration of IFN-gamma in SCID mouse infected by influenza virus FM1]
    Rong Ma
    Hebei North University, Zhangjiakou 075029, China
    Zhongguo Zhong Yao Za Zhi 35:1456-9. 2010
    ..To explore the dynamic effects of Yinqiao detoxifcation oral liquid (YQD) on NK cell lysis in spleen and serum concentration of IFN-gamma in SCID mouse infected by influenza A virus FM1...
  47. pmc Evidence for avian and human host cell factors that affect the activity of influenza virus polymerase
    Olivier Moncorgé
    Department of Virology, Division of Infectious Diseases, Imperial College London, Wright Fleming Institute, Norfolk Place, W2 1PG London, UK
    J Virol 84:9978-86. 2010
    ..Finally, our results strongly suggest that the well-known adaptative mutation E627K on viral protein PB2 facilitates the ability of a human positive factor to enhance replication of influenza virus in human cells...
  48. ncbi [Antiviral and anti-stress activity of the gamma-L-glutamyl-histamine and its derivatives]
    N N Nosik
    Vopr Virusol 48:38-42. 2003
    ..Of all tested agents, gamma-L-Glu-HA derivative II was found to be the most promising...
  49. ncbi [A case of pyomyositis following influenza virus infection]
    Masashi Kohno
    First Department of Internal Medicine, Ehime University, School of Medicine
    Kansenshogaku Zasshi 77:505-9. 2003
    ..Pyomyositis following Influenza virus infection must be considered as a differential diagnosis of myalgia after Influenza virus infection...
  50. ncbi [Influenza in Poland in 2007]
    Magdalena Romanowska
    Krajowy Ośrodek ds Grypy, Narodowy Instytut Zdrowia Publicznego PZH, Warszawa
    Przegl Epidemiol 63:185-9. 2009
    ..Seventeen influenza strains were isolated, including 12 strains of subtype A/H1 and 5 strains of subtype A/H3. All of them were antigenically similar to the vaccine strains recommended for the epidemic season 2006/07...
  51. pmc Comparison of automated microarray detection with real-time PCR assays for detection of respiratory viruses in specimens obtained from children
    Frederic Raymond
    Infectious Disease Research Center of the CHUQ CHUL and Laval University, Sainte Foy, Quebec, Canada
    J Clin Microbiol 47:743-50. 2009
    ..4% of the 221 specimens: 10.0% were positive for HRSV A, 38.0% for HRSV B, 13.1% for influenzavirus A, 8.6% for any coronaviruses, 13.1% for rhinoviruses or enteroviruses, 7.2% for adenoviruses, 4...
  52. ncbi Psychological stress and antibody response to influenza vaccination: a meta-analysis
    Anette Fischer Pedersen
    Psychooncology Research Unit, Department of Psychology, Aarhus University and Aarhus University Hospital, Jens Chr Skous vej 4, 8000 Aarhus C, DK, Denmark
    Brain Behav Immun 23:427-33. 2009
    ..These findings suggest the importance of additional research to explore responsible mechanisms and possible contributions of stress to the public health problem of inadequate responses to vaccination...
  53. pmc Production and characterization of a human recombinant monoclonal Fab fragment specific for influenza A viruses
    Alessandra Desogus
    Sezione di Microbiologia Applicata, Dipartimento di Scienze e Tecnologie Biomediche, Universita di Cagliari, Italy
    Clin Diagn Lab Immunol 10:680-5. 2003
    ..The potential advantages of human recombinant Fabs on murine monoclonal antibodies are discussed...
  54. pmc Temperature-programmed natural convection for micromixing and biochemical reaction in a single microfluidic chamber
    Sung Jin Kim
    Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA
    Anal Chem 81:4510-6. 2009
    ..Our results will significantly simplify micromixing and a subsequent biochemical reaction that involves reagent heating in microfluidic networks...
  55. ncbi Synthesis and in vivo influenza virus-inhibitory effect of ester prodrug of 4-guanidino-7-O-methyl-Neu5Ac2en
    Takeshi Honda
    Medicinal Chemistry Research Laboratories I, Daiichi Sankyo Co, Ltd, Tokyo, Japan
    Bioorg Med Chem Lett 19:2938-40. 2009
    ..Furthermore, the in vivo efficacies of compounds 12a, 12b, and 12c, the linear alkyl ester prodrug of the carboxylic acid, were comparable to that exerted by compound 7c...
  56. ncbi Poly-silicon nanowire field-effect transistor for ultrasensitive and label-free detection of pathogenic avian influenza DNA
    Chih Heng Lin
    Institute of Biological Science and Technology, National Chiao Tung University, Hsinchu 300, Taiwan
    Biosens Bioelectron 24:3019-24. 2009
    ..With its excellent electric properties and potential for mass commercial production, poly-SiNW FET can be developed to become a portable biosensor for field use and point-of-care diagnoses...
  57. ncbi Scalable production of influenza virus in HEK-293 cells for efficient vaccine manufacturing
    Audrey Le Ru
    Animal Cell Technology, National Research Council of Canada, 6100 Royalmount Avenue, Montreal, Quebec, Canada
    Vaccine 28:3661-71. 2010
    ..After virus adaptation and optimization of infection conditions, production in 3-L bioreactor resulted in titers of up to 10(9)IVP/mL demonstrating the scale-up potential of the process...
  58. ncbi Independent and synergistic effects of interleukin-18 and interleukin-12 in augmenting cytotoxic T lymphocyte responses and IFN-gamma production in aging
    Y Zhang
    Influenza Research Center, Respiratory Pathogens Research Unit, Department of Microbiology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA
    J Interferon Cytokine Res 21:843-50. 2001
    ..Potentially, IL-18 and IL-12 can augment IFN-gamma production and reverse CD8(+) CTL deficiency in aging, independently or synergistically...
  59. ncbi Antigenic variation among isolates of infectious salmon anaemia virus correlates with genetic variation of the viral haemagglutinin gene
    F S Kibenge
    Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PEI, Canada C1A 4P3
    J Gen Virol 82:2869-79. 2001
    ..tree was constructed which showed the ISAV sequences to be more closely related to sequences from Influenzavirus A and Influenzavirus B than to sequences from Influenzavirus C and Thogotovirus...
  60. pmc Complications associated with influenza infection
    S D West
    Department of Nephrology, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK
    Postgrad Med J 78:100, 107-8. 2002
  61. pmc Genetic and antigenic analysis of the first A/New Caledonia/20/99-like H1N1 influenza isolates reported in the Americas
    Luke T Daum
    Brooks Air Force Base, San Antonio, TX 78235, USA
    Emerg Infect Dis 8:408-12. 2002
    ..For the 2000/01 and 2001/02 influenza seasons, the World Health Organization (WHO) has recommended the inclusion of A/New Caledonia/20/99 as the H1N1 vaccine component for both the southern and northern hemispheres...
  62. ncbi Combination treatment of influenza A virus infections in cell culture and in mice with the cyclopentane neuraminidase inhibitor RWJ-270201 and ribavirin
    Donald F Smee
    Institute for Antiviral Research, Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah 84322 5600, USA
    Chemotherapy 48:88-93. 2002
    ..Treatment of influenza infections in the clinical setting may benefit by these two agents in combination...
  63. ncbi Accuracy and power of bayes prediction of amino acid sites under positive selection
    Maria Anisimova
    Department of Biology, Galton Laboratory, University College London, United Kingdom
    Mol Biol Evol 19:950-8. 2002
    ....
  64. ncbi Role of influenza A virus hemagglutinin in neurovirulence for mammalians
    Isamu Mori
    Department of Microbiology, Fukui Medical University School of Medicine, Japan
    Med Microbiol Immunol 191:1-4. 2002
    ..Here we review recent advances toward understanding of the possible mechanisms of the neuropathogenesis of influenza virus infection, especially focusing on the role of viral hemagglutinin glycoprotein...
  65. ncbi Unravelling the mysteries of influenza
    Maria Zambon
    Virus Reference Laboratory, Central Public Health Laboratory, NW9 5HT, London, UK
    Lancet 360:1801-2. 2002
  66. ncbi Avian influenza: public health and food safety concerns
    Revis Chmielewski
    Southeast Poultry Research Laboratory, Agricultural Research Service, US Department of Agriculture, Athens, Georgia 30605, USA
    Annu Rev Food Sci Technol 2:37-57. 2011
    Avian influenza (AI) is a disease or asymptomatic infection caused by Influenzavirus A. AI viruses are species specific and rarely cross the species barrier...
  67. ncbi [The formation of the influenza virus aggregates, enriched with hemagglutinin]
    E N Prokudina
    Vopr Virusol 47:17-21. 2002
    ..Possible nature of low-molecular HA-containing structures involved in the aggregates and nature of relations stabilizing aggregates are discussed...
  68. ncbi Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?
    C Y Cheung
    Department of Microbiology, University of Hong Kong, Queen Mary Hospital, SAR, Hong Kong, China
    Lancet 360:1831-7. 2002
    ..The biological basis for the severity of human H5N1 disease has remained unclear. We tested the hypothesis that virus-induced cytokine dysregulation has a role...
  69. ncbi Public perceptions of pandemic influenza resource allocation: a deliberative forum using Grid/Group analysis
    Stynke P Docter
    Faculty of Earth and Life Sciences, The Athena Institute, VU University, De Boelelaan 1081, Amsterdam, The Netherlands
    J Public Health Policy 32:350-66. 2011
    ..There are some differences concerning community involvement in the decision process and information provision to the public, for which our study provides recommendations...
  70. ncbi Miller Fisher syndrome in a toddler with influenza A (pH1N1) infection
    Cecilia T Costiniuk
    University of Ottawa, Faculty of Medicine, Division of Infectious Diseases, Ottawa, Ontario, Canada
    J Child Neurol 26:385-8. 2011
    ..During pandemics, one may expect to see an increased incidence of uncommon neurologic complications of influenza...
  71. pmc Influenza sequence and epitope database
    In Seok Yang
    Department of Biotechnology and Bioinformatics, College of Science and Technology, Korea University, Chungnam, Korea
    Nucleic Acids Res 37:D423-30. 2009
    ..korea.ac.kr and http://influenza.cdc.go.kr...
  72. pmc Antibody responses after inactivated influenza vaccine in young children
    Peter F Wright
    Department of Pediatrics, Vanderbilt School of Medicine, Nashville, TN, USA
    Pediatr Infect Dis J 27:1004-8. 2008
    ....
  73. ncbi Serological response to vaccination against avian influenza in zoo-birds using an inactivated H5N9 vaccine
    Mads F Bertelsen
    Centre for Zoo and Wild Animal Health, Copenhagen Zoo, Roskildevej 38, DK 2000 Frederiksberg, Denmark
    Vaccine 25:4345-9. 2007
    ....
  74. ncbi [Antiviral resistance of influenza viruses]
    Reiko Saito
    Department of Public Health, Niigata University, Graduate School of Medical and Dental Sciences
    Nihon Rinsho 65:471-5. 2007
  75. ncbi Concise synthesis of dideoxy-epigallocatechin gallate (DO-EGCG) and evaluation of its anti-influenza virus activity
    Takumi Furuta
    Department of Synthetic Organic and Medicinal Chemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52 1 Yada, Suruga ku, Shizuoka 422 8526, Japan
    Bioorg Med Chem Lett 17:3095-8. 2007
    ..Compound 2 showed potent anti-influenza virus activity, indicating that the hydroxyl substituents on the A-ring are not crucial for anti-influenza virus activity...
  76. ncbi The rate of influenza immunization to people aged 65 years and older was increased from 45% to 70% by a primary health care-based multiprofessional approach
    Bo Eric Malmvall
    Department of Infectious Diseases, Ryhov Hospital, Jonkoping, Sweden
    Qual Manag Health Care 16:51-9. 2007
    ..Our influenza immunization campaign can act as an example for other healthcare providers...
  77. ncbi Moderate exercise early after influenza virus infection reduces the Th1 inflammatory response in lungs of mice
    Thomas Lowder
    Department of Kinesiology, University of Illinois and Urbana Champaign, Urbana, IL 61801, USA
    Exerc Immunol Rev 12:97-111. 2006
    ..This exercise-induced shift in immune response may be responsible for improved survival after influenza virus infection...
  78. ncbi The association between life events, social support, and antibody status following thymus-dependent and thymus-independent vaccinations in healthy young adults
    Anna C Phillips
    School of Sport and Exercise Sciences, University of Birmingham, UK
    Brain Behav Immun 19:325-33. 2005
    ..Neither psychosocial factor was associated with response to primary meningococcal A polysaccharide vaccination...
  79. ncbi Transient splenial lesion of the corpus callosum in clinically mild influenza-associated encephalitis/encephalopathy
    N Bulakbasi
    Department of Radiology, Gulhane Military Medical Academy, Ankara, Turkey
    AJNR Am J Neuroradiol 27:1983-6. 2006
    ..We present 5 cases with transient diffusion restriction of the SCC associated with influenza A virus infection...
  80. ncbi [Comparison of four rapid diagnostic kits using immunochromatography to detect influenza B viruses]
    Michimaru Hara
    Hara Pediatric Clinic, Hiroshima Prefectural Institute of Public Health and Environmental Science
    Kansenshogaku Zasshi 79:803-11. 2005
    ..All kits were less sensitive to influenza B virus than to influenza A virus, however. The specificity of Quick Vue and Capilia was low; so these kits must be improved...
  81. ncbi Avian influenza virus exhibits rapid evolutionary dynamics
    Rubing Chen
    Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, PA, USA
    Mol Biol Evol 23:2336-41. 2006
    ....
  82. ncbi [A case of influenza A community-acquired pneumonia in an elderly subject hospitalised in intensive care unit]
    L Andreoletti
    Laboratoire de Bacteriologie Virologie Hygiene Hospitaliere, Centre Hospitalier Universitaire de Reims
    Ann Biol Clin (Paris) 63:647-51. 2005
    ..This rapid assay revealed the presence of an Influenzavirus A respiratory infection five days after the beginning of the respiratory syndrome...
  83. ncbi Amantadine resistance among porcine H1N1, H1N2, and H3N2 influenza A viruses isolated in Germany between 1981 and 2001
    Michaela Schmidtke
    Institute of Virology and Antiviral Therapy, Medical Centre of the Friedrich Schiller University Jena, Jena, Germany
    Intervirology 49:286-93. 2006
    ..Therefore, drug susceptibility monitoring appears to be warranted for effective application of those drugs...
  84. ncbi Influenza viruses in general, human strains, shift and drift, vaccination
    M Van Ranst
    Verh K Acad Geneeskd Belg 68:77-80. 2006
  85. ncbi Effects of rutin and quercetin on monooxygenase activities in experimental influenza virus infection
    Varban M Savov
    Medical Physics, Faculty of Physics, Sofia University St Kliment Ohridski, 5 James Boucher Blvd, 1164 Sofia, Bulgaria
    Exp Toxicol Pathol 58:59-64. 2006
    ..More data are needed on the antioxidant/prooxidant effects of rutin and quercetin, probably due to specific metabolic and physiological activities, chemical structure, etc...
  86. ncbi Fate of influenza A virus proteins
    Guang Wu
    Computational Mutation Project, DreamSciTech Consulting Co Ltd, 301, Building 12, Nanyou A zone, Jiannan Road, Shenzhen, Guangdong Province, CN 518054, China
    Protein Pept Lett 13:377-84. 2006
    ....
  87. ncbi [Significance of rapid testing for influenza virus infectious disease]
    Masashi Tanno
    Diagnostics Research Laboratories, Research and Development Division, Daiichi Pure Chemicals Co, Ltd
    Rinsho Byori . 2007
  88. ncbi [Present data on influenza virus isolated from ducks and chickens, and influenza virus C. Anti-influenza drugs]
    José Antonio Cabezas Fernández del Campo
    Académico de Número de la Real Academia Nacional de Farmacia Catedrático Emérito de la Universidad de Salamanca
    An R Acad Nac Med (Madr) 121:305-30. 2004
    ..The sialidase activity of type A virus from ducks and pigs, in comparison with that of humans. Certain sialidase inhibitors as useful anti-influenza drugs, especially in the case of possible future influenza pandemics of avian origin...
  89. ncbi Predominant contribution of IFN-beta expression to apoptosis induction in human uterine cervical fibroblast cells by influenza-virus infection
    Kunio Ohyama
    Department of Clinical Molecular Genetics, Faculty of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo, Japan
    Biol Pharm Bull 27:1750-7. 2004
    ....
  90. ncbi Encephalitis or encephalopathy during an influenza-A epidemic
    Ivan Soldo
    Department of Infectious Diseases, University Hospital Osijek, Osijek, Croatia
    Coll Antropol 27:19-22. 2003
    ..3%) patients in whom encephalitis developed early upon the onset of influenza. One (16.6%) of these patients died, whereas permanent sequels remained in the other two (33.3%) patients...
  91. ncbi [Two types of NP-NP associations in influenza virus-infected cells]
    N P Semenova
    Vopr Virusol 52:9-12. 2007
    ..The NP-multimers untransformed to the folded compact NP-oligomers accumulate in the cells and partially degraded. Whether both types of NP-NP associations may be of significance is under discussion...
  92. ncbi [Synthesis and antiviral activity of lupane triterpenoids with modified cycle E]
    O B Flekhter
    Bioorg Khim 33:629-34. 2007
    ..This is a new approach to a skeletal modification of triterpenoid cycle E. An activity of the synthesized compounds was found toward the viruses of type A influenza and herpes simplex...
  93. ncbi Recent changes in the trends of seasonal influenza outbreaks in the Nagano Prefectural area of Japan: an oseltamivir effect?
    Kozo Yasui
    Department of Pediatrics, Nagano Red Cross Hospital, Wakasato 5 22 1, Nagano 380 8582, Japan
    J Infect Chemother 13:429-31. 2007
    ..To prevent influenza outbreaks having a long duration, we believe that the period of isolation in patients receiving anti-influenza drugs has to be reconsidered...
  94. ncbi [Incidence of influenza and influenza vaccine effectiveness in the 2004-2005 season]
    J Castilla
    Instituto de Salud Pública, Pamplona
    An Sist Sanit Navar 29:97-106. 2006
    ..To quantify the incidence of flu in different groups of the population of Navarra in the 2004-2005 season, and to evaluate the effectiveness of anti-flu vaccination...
  95. ncbi Practical challenges in a hospital pandemic influenza preparedness plan
    Zakir Hussain A Shaikh
    Methodist Dallas Medical Center, USA
    Tex Med 103:38-41. 2007
  96. ncbi Differential expression of sialylglycoconjugates and sialidase activity in distinct morphological stages of Fonsecaea pedrosoi
    Daniela S Alviano
    Instituto de Microbiologia Professor Paulo de Goes, Universidade Federal do Rio de Janeiro, Centro de Ciências da Saúde Bloco I, Ilha do Fundao, 21941 590 Rio de Janeiro, RJ, Brazil
    Arch Microbiol 181:278-86. 2004
    ..These findings suggest that sialic acid expression in F. pedrosoi varies according to the morphological transition and may protect infecting propagules against immune destruction by host cells...
  97. ncbi [Influenza in Poland in 2005]
    Mirosław P Czarkowski
    Zakład Epidemiologii, Państwowy Zakład Higieny, Warszawa
    Przegl Epidemiol 61:207-11. 2007
    ..Besides, RT-PCR method and immunofluorescence test allowed to confirm influenza in other 26 cases and infections with respiratory viruses as RSV, parainfluenza or adenovirus in other 25 cases...
  98. ncbi [Do you have a grip on influenza? (interview by Dr. Thomas Meissner)]
    R Heilbronn
    MMW Fortschr Med 149:16. 2007
  99. ncbi Creating a model program for influenza surveillance in California: results from the 2005-2006 influenza season
    Janice K Louie
    Department of Health Services, Viral and Ricksettial Disease Laboratory, California Department of Public Health, 850 Marina Bay Parkway, Richmond, CA 94804, USA
    Am J Prev Med 33:353-7. 2007
    ..Using the 2005-2006 influenza season as an example, this paper describes a comprehensive influenza surveillance program used by the California Department of Public Health (CDPH)...
  100. ncbi Impact of respiratory infections by influenza viruses A and B in pediatrics patients from Federal University of Paraná, Brazil
    M C Coelho
    Laboratory of Virology, Clinical Hospital, Federal University of Parana, Rua Padre Camargo 280, 28060 240 Curitiba, PR, Brazil
    Braz J Infect Dis 11:220-3. 2007
    ....
  101. ncbi [Influenza in heterothermic animals]
    Dalva Assunção Portari Mancini
    Laboratório de Virologia do Instituto Butantan, Sao Paulo, SP
    Rev Soc Bras Med Trop 37:204-9. 2004
    ..Unlike the toads, 83.3% of the frogs presented mean levels of Ab 40HIU for some influenza strains. It was concluded that heterothermic animals could offer host conditions to the influenza virus and also susceptibility to the infection...