nucleopolyhedrovirus

Summary

Summary: A genus of the family BACULOVIRIDAE, subfamily Eubaculovirinae, characterized by the formation of crystalline, polyhedral occlusion bodies in the host cell nucleus. The type species is Autographa californica nucleopolyhedrovirus.

Top Publications

  1. pmc P74 mediates specific binding of Autographa californica M nucleopolyhedrovirus occlusion-derived virus to primary cellular targets in the midgut epithelia of Heliothis virescens Larvae
    Eric J Haas-Stapleton
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720 3102, USA
    J Virol 78:6786-91. 2004
  2. ncbi Autographa californica nucleopolyhedrovirus infection of Spodoptera frugiperda cells: a global analysis of host gene regulation during infection, using a differential display approach
    Isabelle Nobiron
    Department of Biological Sciences, SAF Building, South Kensington Campus, Imperial College, London SW7 2AZ, UK
    J Gen Virol 84:3029-39. 2003
  3. pmc Autographa californica multicapsid nucleopolyhedrovirus efficiently infects Sf9 cells and transduces mammalian cells via direct fusion with the plasma membrane at low pH
    Sicong Dong
    State Key Laboratory of Virology and Joint Laboratory of Invertebrate Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, People s Republic of China
    J Virol 84:5351-9. 2010
  4. ncbi Dynamic nuclear actin assembly by Arp2/3 complex and a baculovirus WASP-like protein
    Erin D Goley
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA
    Science 314:464-7. 2006
  5. ncbi Sequence analysis of the genome of Bombyx mori nucleopolyhedrovirus
    S Gomi
    Department of Entomology, University of California, Davis 95616, USA
    J Gen Virol 80:1323-37. 1999
  6. ncbi Response of immunocompetent and immunosuppressed Spodoptera littoralis larvae to baculovirus infection
    Hadassah Rivkin
    Entomology Department, Institute of Plant Protection, The Volcani Center, POB 6, Bet Dagan 50250, Israel
    J Gen Virol 87:2217-25. 2006
  7. pmc Autographa californica multiple nucleopolyhedrovirus nucleocapsid protein BV/ODV-C42 mediates the nuclear entry of P78/83
    Yun Wang
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, People s Republic of China
    J Virol 82:4554-61. 2008
  8. pmc Proteomics of the Autographa californica nucleopolyhedrovirus budded virions
    Ranran Wang
    Wuhan Institute of Virology, Chinese Academy of Sciences, Xiaohongshan 44, Wuhan 430071, People s Republic of China
    J Virol 84:7233-42. 2010
  9. pmc Identification of a GP64 subdomain involved in receptor binding by budded virions of the baculovirus Autographica californica multicapsid nucleopolyhedrovirus
    Jian Zhou
    Boyce Thompson Institute at Cornell University, Tower Road, Ithaca, NY 14853, USA
    J Virol 82:4449-60. 2008
  10. pmc The pre-transmembrane domain of the Autographa californica multicapsid nucleopolyhedrovirus GP64 protein is critical for membrane fusion and virus infectivity
    Zhaofei Li
    Boyce Thompson Institute at Cornell University, Tower Road, Ithaca, NY 14853 1801, USA
    J Virol 83:10993-1004. 2009

Research Grants

  1. STRUCTURAL STUDIES OF PROTEINS THAT INHIBIT APOPTOSIS
    Andrew Fisher; Fiscal Year: 2002
  2. Viral DNA Replication and Late Transcription
    Linda Guarino; Fiscal Year: 2004
  3. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin L Hughes; Fiscal Year: 2010
  4. Gene Duplication and Genome Evolution
    Austin Hughes; Fiscal Year: 2004
  5. Highly Improved Bacterial Larvicides for Vector Control
    Brian Federici; Fiscal Year: 2007
  6. Baculovirus envelope proteins and insect cells
    GARY BLISSARD; Fiscal Year: 2009
  7. Apoptosis as an anti-viral response in mosquito midgut
    ROLLIE CLEM; Fiscal Year: 2007
  8. FUNCTIONAL ANALYSIS OF ANTIAPOPTOTIC IAP PROTEINS
    ROLLIE CLEM; Fiscal Year: 2002
  9. INTERACTION OF CLQ ON PHAGOCYTIC CELLS
    Andrea Joan Tenner; Fiscal Year: 2010
  10. Monotonously Ordered Peptide Elements
    Fred Stevens; Fiscal Year: 2008

Detail Information

Publications252 found, 100 shown here

  1. pmc P74 mediates specific binding of Autographa californica M nucleopolyhedrovirus occlusion-derived virus to primary cellular targets in the midgut epithelia of Heliothis virescens Larvae
    Eric J Haas-Stapleton
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720 3102, USA
    J Virol 78:6786-91. 2004
    P74, an envelope protein of the occlusion-derived virus (ODV) of Autographa californica M nucleopolyhedrovirus (AcMNPV), is critical for oral infection of Trichoplusia ni larvae...
  2. ncbi Autographa californica nucleopolyhedrovirus infection of Spodoptera frugiperda cells: a global analysis of host gene regulation during infection, using a differential display approach
    Isabelle Nobiron
    Department of Biological Sciences, SAF Building, South Kensington Campus, Imperial College, London SW7 2AZ, UK
    J Gen Virol 84:3029-39. 2003
    Autographa californica nucleopolyhedrovirus (AcMNPV), the type member of the virus family Baculoviridae, infects pest insects and has been the subject of many studies for its development as a biopesticide...
  3. pmc Autographa californica multicapsid nucleopolyhedrovirus efficiently infects Sf9 cells and transduces mammalian cells via direct fusion with the plasma membrane at low pH
    Sicong Dong
    State Key Laboratory of Virology and Joint Laboratory of Invertebrate Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, People s Republic of China
    J Virol 84:5351-9. 2010
    The budded virus (BV) of the Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) infects insect cells and transduces mammalian cells mainly through the endocytosis pathway...
  4. ncbi Dynamic nuclear actin assembly by Arp2/3 complex and a baculovirus WASP-like protein
    Erin D Goley
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA
    Science 314:464-7. 2006
    ..The baculovirus Autographa californica multiple nucleopolyhedrovirus induced nuclear actin polymerization by translocating the host actin-nucleating Arp2/3 complex into the ..
  5. ncbi Sequence analysis of the genome of Bombyx mori nucleopolyhedrovirus
    S Gomi
    Department of Entomology, University of California, Davis 95616, USA
    J Gen Virol 80:1323-37. 1999
    The genome of the nucleopolyhedrovirus (NPV) (T3 strain) pathogenic for Bombyx mori (Bm) was sequenced and analysed...
  6. ncbi Response of immunocompetent and immunosuppressed Spodoptera littoralis larvae to baculovirus infection
    Hadassah Rivkin
    Entomology Department, Institute of Plant Protection, The Volcani Center, POB 6, Bet Dagan 50250, Israel
    J Gen Virol 87:2217-25. 2006
    ..pest Spodoptera littoralis is highly resistant to infection with the Autographa californica multiple nucleopolyhedrovirus (AcMNPV) via the oral route, but highly sensitive to infection with budded virus (BV) via the ..
  7. pmc Autographa californica multiple nucleopolyhedrovirus nucleocapsid protein BV/ODV-C42 mediates the nuclear entry of P78/83
    Yun Wang
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, People s Republic of China
    J Virol 82:4554-61. 2008
    Autographa californica multiple nucleopolyhedrovirus (AcMNPV) BV/ODV-c42 (orf101; c42), which encodes a 41...
  8. pmc Proteomics of the Autographa californica nucleopolyhedrovirus budded virions
    Ranran Wang
    Wuhan Institute of Virology, Chinese Academy of Sciences, Xiaohongshan 44, Wuhan 430071, People s Republic of China
    J Virol 84:7233-42. 2010
    ..In this study, the protein composition of the BV of Autographa californica nucleopolyhedrovirus (AcMNPV), the type species of baculoviruses, was analyzed by various mass spectrometry (MS) techniques, ..
  9. pmc Identification of a GP64 subdomain involved in receptor binding by budded virions of the baculovirus Autographica californica multicapsid nucleopolyhedrovirus
    Jian Zhou
    Boyce Thompson Institute at Cornell University, Tower Road, Ithaca, NY 14853, USA
    J Virol 82:4449-60. 2008
    ..For budded virions of the baculovirus Autographa californica multicapsid nucleopolyhedrovirus, the envelope glycoprotein GP64 is involved in host cell receptor binding, and GP64 is sufficient to ..
  10. pmc The pre-transmembrane domain of the Autographa californica multicapsid nucleopolyhedrovirus GP64 protein is critical for membrane fusion and virus infectivity
    Zhaofei Li
    Boyce Thompson Institute at Cornell University, Tower Road, Ithaca, NY 14853 1801, USA
    J Virol 83:10993-1004. 2009
    The envelope glycoprotein, GP64, of the baculovirus Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) is a class III viral fusion protein that mediates pH-triggered membrane fusion during virus entry...
  11. ncbi Potent virucidal activity in larval Heliothis virescens plasma against Helicoverpa zea single capsid nucleopolyhedrovirus
    Holly J R Popham
    USDA, Agricultural Research Service, Biological Control of Insects Research Laboratory, 1503 S Providence Road, Columbia, MO 65203, USA
    J Gen Virol 85:2255-61. 2004
    ..An in vitro bioassay was developed in which Helicoverpa zea single capsid nucleopolyhedrovirus (HzSNPV) was incubated with plasma collected from uninfected Heliothis virescens larvae...
  12. pmc Clathrin-independent entry of baculovirus triggers uptake of E. coli in non-phagocytic human cells
    Johanna P Laakkonen
    Department of Biological and Environmental Science Nanoscience Center, University of Jyvaskyla, Jyvaskyla, Finland
    PLoS ONE 4:e5093. 2009
    The prototype baculovirus, Autographa californica multiple nucleopolyhedrovirus, an insect pathogen, holds great potential as a gene therapy vector...
  13. ncbi Analysis of p74, a PDV envelope protein of Autographa californica nucleopolyhedrovirus required for occlusion body infectivity in vivo
    P Faulkner
    Department of Microbiology and Immunology, Queen s University, Kingston, Ontario, Canada
    J Gen Virol 78:3091-100. 1997
    ..Its presence is shown to be essential for primary infection of midgut cells of insect larvae...
  14. pmc Comprehensive analysis of host gene expression in Autographa californica nucleopolyhedrovirus-infected Spodoptera frugiperda cells
    Tamer Z Salem
    Department of Entomology, Michigan State University, East Lansing, MI 48824, USA
    Virology 412:167-78. 2011
    Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) is the best-studied baculovirus and most commonly used virus vector for baculovirus expression vector systems...
  15. ncbi Genomic and host range studies of Maruca vitrata nucleopolyhedrovirus
    Yun Ru Chen
    Department of Entomology, National Taiwan University, Taipei, Taiwan, ROC
    J Gen Virol 89:2315-30. 2008
    The complete genome of the Maruca vitrata nucleopolyhedrovirus (MaviNPV) isolated from the legume pod borer, Maruca vitrata (Lepidoptera: Pyralidae), was sequenced...
  16. ncbi Sequence analysis of the Spodoptera litura multicapsid nucleopolyhedrovirus genome
    Y Pang
    State Key Laboratory for Biocontrol, Zhongshan University, Guangzhou, 510275, China
    Virology 287:391-404. 2001
    The complete Spodoptera litura multicapsid nucleopolyhedrovirus (SpltMNPV) genome contained 139,342 bp with a G+C content of 42...
  17. pmc Characterization of novel components of the baculovirus per os infectivity factor complex
    Ke Peng
    Laboratory of Virology, Wageningen University, Wageningen, The Netherlands
    J Virol 86:4981-8. 2012
    ..combined with proteomic analysis was used to identify the components of the Autographa californica multiple nucleopolyhedrovirus (AcMNPV) PIF complex...
  18. ncbi Discovering microRNAs from Bombyx mori nucleopolyhedrosis virus
    J Singh
    Centre of Excellence for Genetics and Genomics of Silkmoths, Laboratory of Molecular Genetics, Centre for DNA Fingerprinting and Diagnostics, Tuljaguda Complex, Mozamjahi Road, Nampally, Hyderabad 500001, India
    Virology 407:120-8. 2010
    ....
  19. ncbi The gp64 locus of Anticarsia gemmatalis multicapsid nucleopolyhedrovirus contains a 3' repair exonuclease homologue and lacks v-cath and ChiA genes
    Jeffrey M Slack
    Insect Biocontrol Laboratory, USDA, Beltsville, MD 20852, USA
    J Gen Virol 85:211-9. 2004
    Anticarsia gemmatalis multicapsid nucleopolyhedrovirus (AgMNPV) is one of the most successful biological insecticides. In this study, we cloned and sequenced a 12...
  20. ncbi ac109 is required for the nucleocapsid assembly of Autographa californica multiple nucleopolyhedrovirus
    Lin Lin
    State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat Sen University, 510275 Guangzhou, China
    Virus Res 144:130-5. 2009
    ORF109 (Ac109) of Autographa californica multiple nucleopolyhedrovirus (AcMNPV) is a highly conserved gene in all sequenced baculovirus genomes, but its function is not known...
  21. pmc Ac23, an envelope fusion protein homolog in the baculovirus Autographa californica multicapsid nucleopolyhedrovirus, is a viral pathogenicity factor
    Oliver Y Lung
    Boyce Thompson Institute at Cornell University, Ithaca, New York 14853, USA
    J Virol 77:328-39. 2003
    ..Budded virions of group I nucleopolyhedroviruses (NPVs) such as the Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV), contain the essential GP64 envelope fusion protein...
  22. ncbi Characterization of pif, a gene required for the per os infectivity of Spodoptera littoralis nucleopolyhedrovirus
    Iryna Kikhno
    Laboratoire de Pathologie Comparée, UMR 5087 INRA CNRS Université de Montpellier II, 30380 Saint Christol les Ales, France
    J Gen Virol 83:3013-22. 2002
    During plaque purification of Spodoptera littoralis nucleopolyhedrovirus in S. littoralis Sl52 cell culture, a deletion mutant virus was isolated...
  23. ncbi Characterization of the apoptosis suppressor protein P49 from the Spodoptera littoralis nucleopolyhedrovirus
    Zifei Pei
    Entomology Department, Institute of Plant Protection, Agricultural Research Organization, The Volcani Center, POB 6, Bet Dagan, 50250 Israel
    J Biol Chem 277:48677-84. 2002
    ..novel apoptosis suppressor gene and the first homologue of p35, in the genome of the Spodoptera littoralis nucleopolyhedrovirus. Here we show that sl-p49 encodes a 49-kDa protein, confirmed its primary structure that displays 48...
  24. ncbi Autographa californica multiple nucleopolyhedrovirus ac53 plays a role in nucleocapsid assembly
    Chao Liu
    State Key Laboratory of Biocontrol, Sun Yat Sen University, Guangzhou 510275, China
    Virology 382:59-68. 2008
    Autographa californica multiple nucleopolyhedrovirus (AcMNPV) orf53 (ac53) is a highly conserved gene existing in all sequenced Lepidoptera and Hymenoptera baculoviruses, but its function remains unknown...
  25. pmc A baculovirus-encoded MicroRNA (miRNA) suppresses its host miRNA biogenesis by regulating the exportin-5 cofactor Ran
    C P Singh
    Centre of Excellence for Genetics and Genomics of Silkmoths, Laboratory of Molecular Genetics, Centre for DNA Fingerprinting and Diagnostics, Tuljaguda Complex, Nampally, Hyderabad, India
    J Virol 86:7867-79. 2012
    ..mori larvae. The present study provides an insight into one of the evasion strategies used by the virus to counter the host defense for its effective proliferation and has relevance to the development of insect virus control strategies...
  26. pmc Autographa californica multiple nucleopolyhedrovirus ac76 is involved in intranuclear microvesicle formation
    Zhaoyang Hu
    State Key Laboratory of Biocontrol, Sun Yat Sen University, Guangzhou, China
    J Virol 84:7437-47. 2010
    In this study, we characterized Autographa californica multiple nucleopolyhedrovirus (AcMNPV) orf76 (ac76), which is a highly conserved gene of unknown function in lepidopteran baculoviruses...
  27. ncbi Identification of the apoptosis inhibitor gene p49 of Spodoptera litura multicapsid nucleopolyhedrovirus
    Mei Yu
    State Key Laboratory for Biocontrol and Institute of Entomology, Zhongshan University, 510275 Guangzhou, PR China
    Virus Genes 31:145-51. 2005
    ..Computer-assisted analysis indicated that Spodoptera litura multicapsid nucleopolyhedrovirus (SpltMNPV) ORF55 (designated as the p49 gene) display 79 and 31% amino acid identity with Spodoptera ..
  28. pmc Nuclear localization of actin requires AC102 in Autographa californica multiple nucleopolyhedrovirus-infected cells
    Kamal M Gandhi
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720 3102, USA
    J Gen Virol 93:1795-803. 2012
    Autographa californica multiple nucleopolyhedrovirus requires nuclear actin for progeny virus production and thereby encodes viral products that ensure actin's translocation to and retention within the nucleus...
  29. ncbi ac18 is not essential for the propagation of Autographa californica multiple nucleopolyhedrovirus
    Yanjie Wang
    State Key Laboratory of Biocontrol, Sun Yat Sen University, Guangzhou 510275, China
    Virology 367:71-81. 2007
    orf18 (ac18) of Autographa californica multiple nucleopolyhedrovirus (AcMNPV) is a highly conserved gene in lepidopteran nucleopolyhedroviruses, but its function remains unknown...
  30. ncbi Spodoptera litura multicapsid nucleopolyhedrovirus inhibits Microplitis bicoloratus polydnavirus-induced host granulocytes apoptosis
    Kaijun Luo
    State Key Laboratory of Biocontrol and Institute of Entomology, Sun Yat Sen Zhongshan University, Guangzhou 510275, P R China
    J Insect Physiol 52:795-806. 2006
    ..Larvae of the lepidopteran Spodoptera litura were infected by Spodoptera litura multicapsid nucleopolyhedrovirus (SpltMNPV) and then the animals were parasitized by the braconid wasp Microplitis bicoloratus...
  31. pmc Baculovirus per os infectivity factors form a complex on the surface of occlusion-derived virus
    Ke Peng
    Laboratory of Virology, Wageningen University, Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands
    J Virol 84:9497-504. 2010
    ..stable complex on the surface of ODV particles of the baculovirus Autographa californica multinucleocapsid nucleopolyhedrovirus (AcMNPV). The complex could withstand 2% SDS-5% beta-mercaptoethanol with heating at 50 degrees C for 5 min...
  32. ncbi The N-terminal hydrophobic sequence of Autographa californica nucleopolyhedrovirus PIF-3 is essential for oral infection
    X Li
    State Key Laboratory of Virology, Wuhan Institute of Virology, The Chinese Academy of Sciences, Wuhan, PR China
    Arch Virol 152:1851-8. 2007
    The Autographa californica nucleopolyhedrovirus (AcMNPV) open reading frame 115 has been identified as a per os infection factor (pif-3) and is essential for oral infection. Here, we have characterized the pif-3 of AcMNPV in more detail...
  33. ncbi Cell-cycle perturbation in Sf9 cells infected with Autographa californica nucleopolyhedrovirus
    M Ikeda
    Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa, Nagoya, 464 8601, Japan
    Virology 258:176-88. 1999
    ..analysis of the cell-cycle progression was performed in Sf9 cells infected with Autographa californica nucleopolyhedrovirus (AcNPV) in the cultures partially synchronized by aphidicolin exposure and deprivation...
  34. pmc The putative pocket protein binding site of Autographa californica nucleopolyhedrovirus BV/ODV-C42 is required for virus-induced nuclear actin polymerization
    Kun Li
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, People s Republic of China
    J Virol 84:7857-68. 2010
    ..Previously, we had demonstrated that Autographa californica multiple nucleopolyhedrovirus (AcMNPV) BV/ODV-C42 (C42) is involved in nuclear actin polymerization by recruiting P78/83, an AcMNPV orf9-..
  35. pmc Inactivation of the budded virus of Autographa californica M nucleopolyhedrovirus by gloverin
    Daniela A Moreno-Habel
    Department of Biological Sciences, California State University Long Beach, Long Beach, CA 90840, USA
    J Invertebr Pathol 110:92-101. 2012
    ..ni systemically infected with the baculovirus Autographa californica M nucleopolyhedrovirus (AcMNPV). Two gloverin genes were cloned using RNA isolated from the hemocytes of T...
  36. ncbi Targeting ie-1 gene by RNAi induces baculoviral resistance in lepidopteran cell lines and in transgenic silkworms
    S Kanginakudru
    Laboratory of Molecular Genetics, Centre for DNA Fingerprinting and Diagnostics, ECIL Road, Nacharam, Hyderabad, India
    Insect Mol Biol 16:635-44. 2007
    ..mori nucleopolyhedrovirus infection, with nearly 40% protection compared with nontransgenic animals...
  37. pmc Autographa californica multiple nucleopolyhedrovirus 38K is a novel nucleocapsid protein that interacts with VP1054, VP39, VP80, and itself
    Wenbi Wu
    State Key Laboratory of Biocontrol, Sun Yat Sen University, Guangzhou 510275, China
    J Virol 82:12356-64. 2008
    It has been shown that the Autographa californica multiple nucleopolyhedrovirus (AcMNPV) 38K (ac98) is required for nucleocapsid assembly. However, the exact role of 38K in nucleocapsid assembly remains unknown...
  38. ncbi Interaction of Bombyx mori nucleopolyhedrovirus BRO-A and host cell protein laminin
    W K Kang
    Laboratory of Molecular Entomology and Baculovirology, RIKEN, Wako, Japan
    Arch Virol 148:99-113. 2003
    The Bombyx mori nucleopolyhedrovirus (BmNPV) contains five baculovirus repeated ORF ( bro) genes, all of which are expressed as delayed early genes...
  39. pmc Sequence and organization of the Neodiprion lecontei nucleopolyhedrovirus genome
    Hilary A M Lauzon
    Canadian Forest Service, Great Lakes Forestry Centre, Sault Ste Marie, Ontario, Canada P6A 2E5
    J Virol 78:7023-35. 2004
    All fully sequenced baculovirus genomes, with the exception of the dipteran Culex nigripalpus nucleopolyhedrovirus (CuniNPV), have previously been from Lepidoptera...
  40. pmc Sequence analysis of the genome of the Neodiprion sertifer nucleopolyhedrovirus
    Alejandra Garcia-Maruniak
    Entomology and Nematology Department, University of Florida, Gainesville, FL 32611 0620, USA
    J Virol 78:7036-51. 2004
    The genome of the Neodiprion sertifer nucleopolyhedrovirus (NeseNPV), which infects the European pine sawfly, N. sertifer (Hymenoptera: Diprionidae), was sequenced and analyzed. The genome was 86,462 bp in size...
  41. ncbi A high efficient method of constructing recombinant Bombyx mori (silkworm) multiple nucleopolyhedrovirus based on zero-background Tn7-mediated transposition in Escherichia coli
    Jing Chen Sun
    College of Animal Science, South China Agricultural University, Guangzhou 510642, PR China
    Biotechnol Prog 25:524-9. 2009
    A high efficient way for generation of recombinant Bombyx mori (silkworm) multiple nucleopolyhedrovirus by Tn7-mediated transposition in Escherichia coli was performed...
  42. pmc Autographa californica nucleopolyhedrovirus orf69 encodes an RNA cap (nucleoside-2'-O)-methyltransferase
    Xiaofeng Wu
    Department of Biochemistry, Texas A and M University, College Station, Texas 77843 2128, USA
    J Virol 77:3430-40. 2003
    ..Immunoblot analysis confirmed that MTase1 was not synthesized in these cells, and single-step growth curves revealed that the rate of virus replication in tissue culture was not affected by the absence of MTase1...
  43. ncbi Characterization of a late gene, ORF67 from Bombyx mori nucleopolyhedrovirus
    Hui Qing Chen
    Institute of Life Sciences, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, PR China
    FEBS Lett 581:5836-42. 2007
    Open reading frame 67 of Bombyx mori nucleopolyhedrovirus (BmORF67) is a homologue of Autographa californica multiple NPV ORF81. The gene is conserved among all baculoviruses and is thus considered a baculovirus core gene...
  44. ncbi Kinetic characterization of the group II Helicoverpa armigera nucleopolyhedrovirus propagated in suspension cell cultures: implications for development of a biopesticides production process
    Marcia R S Pedrini
    Núcleo Tecnológico, Programa de Pós Graduação em Engenharia Química, Universidade Federal do Rio Grande do Norte, Campus Universitario, Lagoa Nova, CEP 59072 970, Natal, Brazil
    Biotechnol Prog 27:614-24. 2011
    ..have so far only been reported for the commercially established recombinant Autographa californica nucleopolyhedrovirus (AcMNPV), a Group I NPV...
  45. ncbi Comparative analysis of the complete genome sequences of Helicoverpa zea and Helicoverpa armigera single-nucleocapsid nucleopolyhedroviruses
    Xinwen Chen
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    J Gen Virol 83:673-84. 2002
    The complete nucleotide sequence of Helicoverpa zea single-nucleocapsid nucleopolyhedrovirus (HzSNPV) has been determined (130869 bp) and compared to the nucleotide sequence of Helicoverpa armigera (Ha) SNPV...
  46. pmc Autographa californica multiple nucleopolyhedrovirus core gene ac96 encodes a per Os infectivity factor (PIF-4)
    Minggang Fang
    Pacific Agri Food Research Centre, Agriculture and Agri Food Canada, Summerland, British Columbia, Canada
    J Virol 83:12569-78. 2009
    Autographa californica multiple nucleopolyhedrovirus (AcMNPV) ac96 is a core gene, but its role in virus replication is still unknown...
  47. ncbi Deletion of the Autographa californica nucleopolyhedrovirus chitinase KDEL motif and in vitro and in vivo analysis of the modified virus
    Giles P Saville
    School of Biological and Molecular Sciences, Gipsy Lane Campus, Oxford Brookes University, Oxford OX3 0BP, UK
    J Gen Virol 85:821-31. 2004
    Infection of insect larvae with Autographa californica nucleopolyhedrovirus (AcMNPV) results in the liquefaction of the host, a process involving the action of virus-encoded chitinase and cathepsin gene products...
  48. ncbi Autographa californica multiple nucleopolyhedrovirus ODV-E56 is a per os infectivity factor, but is not essential for binding and fusion of occlusion-derived virus to the host midgut
    Wendy O Sparks
    Genetics Program, Department of Entomology, Iowa State University, Ames, IA 50011, USA
    Virology 409:69-76. 2011
    The Autographa californica multiple nucleopolyhedrovirus (AcMNPV) occlusion-derived virus (ODV) envelope protein ODV-E56 is essential for oral infection of larvae of Heliothis virescens...
  49. ncbi The sequence of the Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus genome
    X Chen
    Joint-Laboratory of Invertebrate Virology, Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei 430071, People's Republic of China
    J Gen Virol 82:241-57. 2001
    The nucleotide sequence of the Helicoverpa armigera single-nucleocapsid nucleopolyhedrovirus (HaSNPV) DNA genome was determined and analysed. The circular genome encompasses 131,403 bp, has a G+C content of 39...
  50. ncbi The genome sequence of the multinucleocapsid nucleopolyhedrovirus of the Chinese oak silkworm Antheraea pernyi
    Qi Fan
    Dalian Institute of Biotechnology, Liaoning Academy of Agricultural Sciences, Dalian, Liaoning Province, 116024 China
    Virology 366:304-15. 2007
    The complete genome sequence of the Liaoning isolate of the Antheraea pernyi multinucleocapsid nucleopolyhedrovirus (AnpeMNPV) was determined. The viral genome size is 126,246 bp, relatively GC-rich (53...
  51. ncbi Genome sequence of an enhancin gene-rich nucleopolyhedrovirus (NPV) from Agrotis segetum: collinearity with Spodoptera exigua multiple NPV
    Agata K Jakubowska
    Department of Biological Control and Quarantine, Institute of Plant Protection, Miczurina 20, Poznan 60 318, Poland
    J Gen Virol 87:537-51. 2006
    The genome sequence of a Polish isolate of Agrotis segetum nucleopolyhedrovirus (AgseNPV-A) was determined and analysed. The circular genome is composed of 147,544 bp and has a G+C content of 45.7 mol%...
  52. ncbi The BRO proteins of Bombyx mori nucleopolyhedrovirus are nucleocytoplasmic shuttling proteins that utilize the CRM1-mediated nuclear export pathway
    Wonkyung Kang
    Molecular Entomology Laboratory, RIKEN, 2 1 Hirosawa, Wako 351 0198, Japan
    Virology 350:184-91. 2006
    The BRO proteins of Bombyx mori nucleopolyhedrovirus (BmNPV) display a biphasic pattern of intracellular localization during infection...
  53. ncbi Genomic sequence analysis of a fast-killing isolate of Spodoptera frugiperda multiple nucleopolyhedrovirus
    Robert L Harrison
    Agricultural Research Service, Plant Sciences Institute, Beltsville, MD 20705, USA
    J Gen Virol 89:775-90. 2008
    Six clones of Spodoptera frugiperda multiple nucleopolyhedrovirus (SfMNPV) were plaque-purified from field isolates collected in Missouri, USA. In bioassays, four of the plaque-purified isolates killed neonate S...
  54. ncbi The Heliothis armigera single nucleocapsid nucleopolyhedrovirus envelope protein P74 is required for infection of the host midgut
    Lunguang Yao
    Department of Virology, College of Life Sciences, Wuhan University, Hubei, 430072, PR China
    Virus Res 104:111-21. 2004
    In order to study the function of the envelope protein P74 of Heliothis armigera single nucleocapsid nucleopolyhedrovirus (HaSNPV), a p74-null recombinant baculovirus, rHa-gfdeltap74, was constructed by inserting gfp driven by the ..
  55. ncbi Comparison of the complete genome sequence between C1 and G4 isolates of the Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus
    Chuan Xi Zhang
    Institute of Applied Entomology, Zhejiang University, Kaixuan Road 268, Hangzhou, Zhejiang 310029, China
    Virology 333:190-9. 2005
    The complete nucleotide sequence of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus isolate C1 (HearSNPV-C1) was determined and analyzed by comparing with the genome of HearSNPV-G4 isolate...
  56. ncbi Complete comparative genomic analysis of two field isolates of Mamestra configurata nucleopolyhedrovirus-A
    Lulin Li
    Pacific Agri Food Research Centre, AAFC, Summerland, BC, Canada
    J Gen Virol 86:91-105. 2005
    A second genotype of Mamestra configurata nucleopolyhedrovirus-A (MacoNPV-A), variant 90/4 (v90/4), was identified due to its altered restriction endonuclease profile and reduced virulence for the host insect, M...
  57. ncbi The role of the PI3K-Akt signal transduction pathway in Autographa californica multiple nucleopolyhedrovirus infection of Spodoptera frugiperda cells
    Wei Xiao
    State Key Laboratory of Biocontrol, Sun Yat Sen University, Guangzhou 510275, China
    Virology 391:83-9. 2009
    ..In the present study, we demonstrate that infection of Sf9 cells with Autographa californica multiple nucleopolyhedrovirus (AcMNPV) elevated cellular Akt phosphorylation at 1 h post-infection...
  58. ncbi Genome sequence of Leucania seperata nucleopolyhedrovirus
    Huazhong Xiao
    Institute of Virology, Wuhan University, Wuhan 430072, PR China
    Virus Genes 35:845-56. 2007
    The nucleotide sequence of the Leucania seperata (Ls) Nucleopolyhedrovirus (LsNPV) genome has been determined and analyzed. The circular dsDNA genome contains 168041 bp, making it the largest NPV sequenced to date...
  59. ncbi Morphology and genome of Euproctis pseudoconspersa nucleopolyhedrovirus
    Xu Dong Tang
    Institute of Insect Science, Zhejiang University, 268 Kaixuan Road, Hangzhou, 310029, China
    Virus Genes 38:495-506. 2009
    ..Gene parity plots, percent identities of gene homologues and phylogenetic analysis all suggested that EupsNPV is most closely related to EcobNPV in Group II NPV, although its genomic organization was highly distinct...
  60. pmc A baculovirus-encoded protein tyrosine phosphatase gene induces enhanced locomotory activity in a lepidopteran host
    Shizuo G Kamita
    Department of Entomology, University of California, 1 Shields Avenue, Davis, CA 95616, USA
    Proc Natl Acad Sci U S A 102:2584-9. 2005
    ..ELA was induced in silkworm Bombyx mori infected with the baculovirus B. mori nucleopolyhedrovirus (BmNPV) beginning at approximately 3.75 days postinfection (p.i.) and continued until 4.75 days p.i...
  61. pmc Functional entry of baculovirus into insect and mammalian cells is dependent on clathrin-mediated endocytosis
    Gang Long
    State Key Laboratory of Virology, Key Laboratory of Molecular Virology and Joint Lab of Invertebrate Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, People s Republic of China
    J Virol 80:8830-3. 2006
    ..Our results further suggest that caveolae are somehow involved in baculovirus entry in mammalian cells. A caveolar endocytosis inhibitor, genistein, enhances baculovirus transduction in these cells considerably...
  62. ncbi Baculoviruses-- re-emerging biopesticides
    Boguslaw Szewczyk
    Department of Molecular Virology, Intercollegiate Faculty of Biotechnology of the University of Gdansk and Medical University of Gdansk, Kladki 24, 80 822 Gdansk, Poland
    Biotechnol Adv 24:143-60. 2006
    ..It is expected that the baculoviruses improved by genetic modifications will be gradually introduced in countries which have fewer concerns towards genetically modified organisms...
  63. ncbi Influence of cytochrome c on apoptosis induced by Anagrapha (Syngrapha) falcifera multiple nuclear polyhedrosis virus (AfMNPV) in insect Spodoptera litura cells
    Lijun Liu
    Institute of Entomology, Ministry of Education, Central China Normal University, Wuhan 430079, China
    Cell Biol Int 31:996-1001. 2007
    ..These data indicate that cytochrome c plays a key role in AfMNPV-induced apoptosis in S. litura cells and may be required for caspase activation during the induction of apoptosis...
  64. pmc Baculovirus infection of nondividing mammalian cells: mechanisms of entry and nuclear transport of capsids
    N D van Loo
    Department of Cell Biology, Erasmus University, 3000 DR Rotterdam, The Netherlands
    J Virol 75:961-70. 2001
    ..The implications for the application of baculovirus or its capsid proteins in gene therapy are discussed...
  65. pmc Baculovirus entry into human hepatoma cells
    Heli Matilainen
    University of Jyvaskyla, Nano Science Center, Department of Biological and Environmental Science, PO Box 35, FIN 40351 Jyvaskyla, Finland
    J Virol 79:15452-9. 2005
    Autographa californica multiple nucleopolyhedrovirus (AcMNPV), a prototype member of the Baculoviridae family, has gained increasing interest as a potential vector candidate for mammalian gene delivery applications...
  66. ncbi Baculovirus envelope fusion proteins F and GP64 exploit distinct receptors to gain entry into cultured insect cells
    Marcel Westenberg
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    J Gen Virol 88:3302-6. 2007
    ....
  67. pmc A lipase isolated from the silkworm Bombyx mori shows antiviral activity against nucleopolyhedrovirus
    Kangayam M Ponnuvel
    Innate Immunity Laboratory, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305 8634, Japan
    J Virol 77:10725-9. 2003
    A protein showing strong antiviral activity against Bombyx mori nucleopolyhedrovirus (BmNPV) was purified from the digestive juice of B. mori larvae...
  68. pmc Specific binding of Autographa californica M nucleopolyhedrovirus occlusion-derived virus to midgut cells of Heliothis virescens larvae is mediated by products of pif genes Ac119 and Ac022 but not by Ac115
    Taro Ohkawa
    Department of Plant and Microbial Biology, 251 Koshland Hall, Berkeley, CA 94720 3102, USA
    J Virol 79:15258-64. 2005
    ..like P74, are essential for oral infection of lepidopteran larval hosts of Autographa californica M nucleopolyhedrovirus (AcMNPV)...
  69. pmc Early synthesis of budded virus envelope fusion protein GP64 enhances Autographa californica multicapsid nucleopolyhedrovirus virulence in orally infected Heliothis virescens
    Jan O Washburn
    Department of Plant and Microbial Biology, University of California, Berkeley 94720 3102, USA
    J Virol 77:280-90. 2003
    Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV), the type species of the Nucleopolyhedrovirus genus (Baculoviridae family), has two highly unusual traits shared by several baculovirus species...
  70. pmc Characterization of baculovirus repeated open reading frames (bro) in Bombyx mori nucleopolyhedrovirus
    W Kang
    Laboratory of Molecular Entomology, RIKEN The Institute of Physical and Chemical Research, Wako, Japan
    J Virol 73:10339-45. 1999
    The baculovirus Bombyx mori nucleopolyhedrovirus (BmNPV) contains five related open reading frames (ORFs)...
  71. ncbi Characterization of the replication of a baculovirus mutant lacking the DNA polymerase gene
    Adam L Vanarsdall
    Department of Microbiology, Nash Hall Room 220, Oregon State University, Corvallis, OR 97331 3804, USA
    Virology 331:175-80. 2005
    In a previous study, the DNA polymerase gene (dnapol) of Autographa californica multiple nucleopolyhedrovirus (AcMNPV) was identified as one of six genes required for plasmid replication in a transient replication assay (M. Kool, C...
  72. pmc The highly conserved basic domain I of baculovirus IE1 is required for hr enhancer DNA binding and hr-dependent transactivation
    Victoria A Olson
    Institute for Molecular Virology and Department of Biochemistry, Graduate School and College of Agricultural and Life Sciences, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Virol 77:5668-77. 2003
    ..protein IE1 is the principal transcriptional regulator of the baculovirus Autographa californica nucleopolyhedrovirus (AcMNPV)...
  73. pmc Actin-based motility drives baculovirus transit to the nucleus and cell surface
    Taro Ohkawa
    Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA
    J Cell Biol 190:187-95. 2010
    ..In this study, we show that nucleocapsids of the baculovirus Autographa californica multiple nucleopolyhedrovirus undergo intracellular motility driven by actin polymerization...
  74. ncbi Cloning of biologically active genomes from a Helicoverpa armigera single-nucleocapsid nucleopolyhedrovirus isolate by using a bacterial artificial chromosome
    Hanzhong Wang
    Joint Laboratory of Invertebrate Virology and Key Laboratory of Molecular Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, PR China
    Virus Res 97:57-63. 2003
    ..we report the cloning of different genotypes from an isolate of Helicoverpa armigera single-nucleocapsid nucleopolyhedrovirus (HaSNPV) by using a bacterial artificial chromosome (BAC)...
  75. pmc Complete sequence and organization of Antheraea pernyi nucleopolyhedrovirus, a dr-rich baculovirus
    Zuo Ming Nie
    Institute of Biochemistry, Zhejiang Sci Tech University, Hangzhou, PR China
    BMC Genomics 8:248. 2007
    ..However, there is no report of the Antheraea pernyi nucleopolyhedrovirus (AnpeNPV) genome.
  76. pmc Characterization of a baculovirus lacking the DBP (DNA-binding protein) gene
    Adam L Vanarsdall
    Department of Microbiology, Nash Hall Room 220, Oregon State University, Corvallis, OR 97331 3804, USA
    Virology 364:475-85. 2007
    Autographa californica multiple nucleopolyhedrovirus (AcMNPV) encodes two proteins that possess properties typical of single-stranded DNA-binding proteins (SSBs), late expression factor-3 (LEF-3), and a protein referred to as DNA-binding ..
  77. pmc Identification of six Autographa californica multicapsid nucleopolyhedrovirus early genes that mediate nuclear localization of G-actin
    Taro Ohkawa
    Department of Plant and Microbial Biology, University of California, Berkeley, California 94720 3102, USA
    J Virol 76:12281-9. 2002
    Nuclear filamentous actin (F-actin) is required for nucleopolyhedrovirus (NPV) progeny production in NPV-infected, cultured lepidopteran cells...
  78. pmc Determination of the protein composition of the occlusion-derived virus of Autographa californica nucleopolyhedrovirus
    S C Braunagel
    Department of Chemistry, Texas Agricultural Experiment Station, Texas A and M University, College Station, TX 77843 2475, USA
    Proc Natl Acad Sci U S A 100:9797-802. 2003
    ..With knowledge of the composition of ODV, it is now possible to target proteins and study their role(s) during primary infection...
  79. ncbi Genome-wide analysis of host gene expression in the silkworm cells infected with Bombyx mori nucleopolyhedrovirus
    Aki Sagisaka
    Innate Immunity Research Unit, National Institute of Agrobiological Sciences, 1 2 Owashi, Tsukuba, Ibaraki 305 8634, Japan
    Virus Res 147:166-75. 2010
    ..transcriptional profile of host genes in the silkworm cell line during the early phase of Bombyx mori nucleopolyhedrovirus (BmNPV) infection was analyzed by oligonucleotide microarray...
  80. pmc Autographa californica multiple nucleopolyhedrovirus nucleocapsid assembly is interrupted upon deletion of the 38K gene
    Wenbi Wu
    State Key Laboratory of Biocontrol, Sun Yat Sen University, Guangzhou 510275, People s Republic of China
    J Virol 80:11475-85. 2006
    38K (ac98) of Autographa californica multiple nucleopolyhedrovirus (AcMNPV) is a highly conserved baculovirus gene whose function is unknown...
  81. ncbi Gene expression profiling of resistant and susceptible Bombyx mori strains reveals nucleopolyhedrovirus-associated variations in host gene transcript levels
    Yan Yuan Bao
    Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Ministry of Agriculture, Institute of Insect Sciences, Zhejiang University, Hangzhou, 310029, China
    Genomics 94:138-45. 2009
    We investigated variations in the gene expression of Bombyx mori following infection with a nucleopolyhedrovirus (BmNPV). Two B...
  82. ncbi Sequence and organization of the Mamestra configurata nucleopolyhedrovirus genome
    Qianjun Li
    Saskatoon Research Centre, Agriculture and Agri Food Canada, Saskatoon, Saskatchewan, S7N 0X2 Canada
    Virology 294:106-21. 2002
    The nucleotide sequence of the genome of the nucleopolyhedrovirus (NPV) from Mamestra configurata (MacoNPV, isolate 90/2), a group II NPV, was determined and analyzed...
  83. ncbi Sequence analysis of the complete genome of Trichoplusia ni single nucleopolyhedrovirus and the identification of a baculoviral photolyase gene
    Leslie G Willis
    Pacific Agri Food Research Centre, Agriculture and Agri Food Canada, 4200 Highway 97, Summerland, BC, Canada
    Virology 338:209-26. 2005
    The genome of the Trichoplusia ni single nucleopolyhedrovirus (TnSNPV), a group II NPV which infects the cabbage looper (T. ni), has been completely sequenced and analyzed...
  84. ncbi Genome sequence and organization of a nucleopolyhedrovirus that infects the tea looper caterpillar, Ectropis obliqua
    Xiu Cui Ma
    Institute of Insect Science, Zhejiang University, 268 Kaixuan Road, Hangzhou, 310029, China
    Virology 360:235-46. 2007
    The complete nucleotide sequence of Ectropis obliqua nucleopolyhedrovirus (EcobNPV), which infects the tea looper caterpillar, was determined and analyzed. The double stranded circular genome is composed of 131,204 bp and is 37...
  85. ncbi Genomic sequence and biological characterization of a nucleopolyhedrovirus isolated from the summer fruit tortrix, Adoxophyes orana
    Sally Hilton
    Warwick HRI, Wellesbourne, Warwick CV35 9EF, UK
    J Gen Virol 89:2898-908. 2008
    Adoxophyes orana nucleopolyhedrovirus (AdorNPV) was isolated from overwintering larvae from an orchard in the UK. The nucleotide sequence of the AdorNPV DNA genome was determined and analysed...
  86. ncbi Inter-subunit interactions of the Autographa californica M nucleopolyhedrovirus RNA polymerase
    Erin A Crouch
    Molecular, Cellular, and Developmental Biology Program, Division of Biology, 116 Ackert Hall, Kansas State University, Manhattan, KS 66506 4901, USA
    Virology 367:265-74. 2007
    Autographa californica M nucleopolyhedrovirus transcribes genes using two DNA-directed RNA polymerases; early genes are transcribed by the host RNA polymerase II, and late and very late genes are transcribed by a viral-encoded ..
  87. pmc Analysis of an Autographa californica multicapsid nucleopolyhedrovirus lef-6-null virus: LEF-6 is not essential for viral replication but appears to accelerate late gene transcription
    Guangyun Lin
    Boyce Thompson Institute at Cornell University, Ithaca, New York 14853 1801, USA
    J Virol 76:5503-14. 2002
    The Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) lef-6 gene was previously shown to be necessary for optimal transcription from an AcMNPV late promoter in transient late expression assays...
  88. ncbi Determination of protein composition and host-derived proteins of Bombyx mori nucleopolyhedrovirus by 2-dimensional electrophoresis and mass spectrometry
    Xiaoyong Liu
    Institute of Life Sciences, Jiangsu University, Zhenjiang, PR China
    Intervirology 51:369-76. 2008
    ..The virion contains proteins essential for host-range determination and initiation of infection. Determination of protein composition of the occlusion-derived virus (ODV) will help us to understand this virion's infection mechanism...
  89. ncbi Involvement of Bombyx mori nucleopolyhedrovirus ORF41 (Bm41) in BV production and ODV envelopment
    Cai Hong Tian
    Institute of Insect Science, and Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Ministry of Agriculture, Zhejiang University, Hangzhou 310029, China
    Virology 387:184-92. 2009
    Bombyx mori nucleopolyhedrovirus (BmNPV) ORF41 (Bm41), homologous to Ac52, is a gene present in most lepidopteran nucleopolyhedroviruses...
  90. ncbi Open reading frame Bm21 of Bombyx mori nucleopolyhedrovirus is not essential for virus replication in vitro, but its deletion extends the median survival time of infected larvae
    Jinshan Huang
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, PR China
    J Gen Virol 89:922-30. 2008
    In this report, the open reading frame 21 (Bm21) of Bombyx mori nucleopolyhedrovirus (BmNPV), one of the unique genes of group I NPVs, was characterized. Bm21 is predicted to encode a protein of 55...
  91. ncbi Abortive replication of Bombyx mori nucleopolyhedrovirus in Sf9 and High Five cells: defective nuclear transport of the virions
    Yasuhiro Katou
    Laboratory of Biodynamics, Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa, Nagoya 464 8601, Japan
    Virology 347:455-65. 2006
    Despite close genetic relationship, Bombyx mori nucleopolyhedrovirus (BmNPV) and Autographa californica multicapsid NPV (AcMNPV) display a distinct host range property...
  92. ncbi Role of the ubiquitin-proteasome system in Bombyx mori nucleopolyhedrovirus infection
    Susumu Katsuma
    Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1 1 1, Bunkyo ku, Tokyo 113 8657, Japan
    J Gen Virol 92:699-705. 2011
    ..Furthermore, Western blots also showed that v-UBI was not required for degradation of IE2, which is known as a target viral protein of the ubiquitin-proteasome system...
  93. pmc Identification of Autographa californica nucleopolyhedrovirus ac93 as a core gene and its requirement for intranuclear microvesicle formation and nuclear egress of nucleocapsids
    Meijin Yuan
    State Key Laboratory of Biocontrol, Sun Yat Sen University, Guangzhou 510275, China
    J Virol 85:11664-74. 2011
    Autographa californica nucleopolyhedrovirus (AcMNPV) orf93 (ac93) is a highly conserved uncharacterized gene that is found in all of the sequenced baculovirus genomes except for Culex nigripalpus NPV...
  94. ncbi Combined effect of nucleopolyhedrovirus and Microplitis pallidipes for the control of the beet armyworm, Spodoptera exigua
    Jiexian Jiang
    Ecological Environment Protection Research Institute, Shanghai Academy of Agricultural Sciences, Shanghai Key Laboratory of Protected Horticultural Technology, Shanghai 201106, China
    Pest Manag Sci 67:705-13. 2011
    b>Nucleopolyhedrovirus (SeNPV) and Microplitis pallidipes are important biological control agents of Spodoptera exigua populations...
  95. ncbi Identification of a nucleopolyhedrovirus in winter moth populations from Massachusetts
    John P Burand
    Department of Plant, Soil and Insect Science, University of Massachusetts Amherst, Amherst, MA 01003, USA
    J Invertebr Pathol 108:217-9. 2011
    ..We identified O. brumata nucleopolyhedrovirus (OpbuNPV) in winter moth larvae collected from field sites in Massachusetts by using PCR to amplify a 482 ..
  96. ncbi Genetic variation and virulence of nucleopolyhedroviruses isolated worldwide from the heliothine pests Helicoverpa armigera, Helicoverpa zea, and Heliothis virescens
    Daniel L Rowley
    Invasive Insect Biocontrol and Behavior Laboratory, Plant Sciences Institute, USDA Agricultural Research Service, 10300 Baltimore Avenue, Beltsville, MD 20705, USA
    J Invertebr Pathol 107:112-26. 2011
    ..found in insects of the heliothine pest complex, a PCR-based method was used to classify 90 samples of nucleopolyhedrovirus (NPV; Baculoviridae: Alphabaculovirus) obtained worldwide from larvae of Heliothis virescens, Helicoverpa ..
  97. ncbi Juvenile hormone analog technology: effects on larval cannibalism and the production of Spodoptera exigua (Lepidoptera: Noctuidae) nucleopolyhedrovirus
    Sonia Elvira
    Departamento de Producción Agraria, Universidad Publica de Navarra, Pamplona 31006, Spain
    J Econ Entomol 103:577-82. 2010
    The production of a multiple nucleopolyhedrovirus (SeMNPV) of the beet armyworm, Spodoptera exigua (Hübner) (Lepidoptera: Noctuidae), has been markedly increased by using juvenile hormone analog (JHA) technology to generate a ..
  98. pmc Autographa californica multiple nucleopolyhedrovirus me53 (ac140) is a nonessential gene required for efficient budded-virus production
    Jondavid de Jong
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    J Virol 83:7440-8. 2009
    ..Together, these results indicate that me53, although not essential for viral replication, is required for efficient BV production...
  99. pmc A functional F analogue of Autographa californica nucleopolyhedrovirus GP64 from the Agrotis segetum granulovirus
    Feifei Yin
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
    J Virol 82:8922-6. 2008
    ..granulovirus is a computational analogue of the GP64 envelope fusion protein of Autographa californica nucleopolyhedrovirus (AcMNPV)...
  100. ncbi Confocal microscopic observation of fusion between baculovirus budded virus envelopes and single giant unilamellar vesicles
    Koki Kamiya
    Department of Chemistry for Materials, Graduate School of Engineering, Mie University, 1577 Kurimamachiya cho, Tsu, Mie 514 8507, Japan
    Biochim Biophys Acta 1798:1625-31. 2010
    ..between giant unilamellar vesicles (GUVs) and budded viruses (BVs) of baculovirus (Autographa californica nucleopolyhedrovirus), the envelopes of which have been labeled with the fluorescent dye Alexa Fluor 488...
  101. ncbi Characterization of late gene expression factors lef-9 and lef-8 from Bombyx mori nucleopolyhedrovirus
    Asha Acharya
    Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India
    J Gen Virol 83:2015-23. 2002
    ..Peak levels of lef-8 transcripts were attained by 24 h p.i. Immunocopurification analyses suggested that there was an association between LEF-8 and LEF-9 in vivo...

Research Grants11

  1. STRUCTURAL STUDIES OF PROTEINS THAT INHIBIT APOPTOSIS
    Andrew Fisher; Fiscal Year: 2002
    ..The gene p35 from the Autographa californica nucleopolyhedrovirus, a baculovirus, inhibits a broad spectrum of caspases, suppressing apoptosis...
  2. Viral DNA Replication and Late Transcription
    Linda Guarino; Fiscal Year: 2004
    ..Knowledge gained from these experiments should be relevant to other viral systems and will provide a better understanding of the complex interactions between transcription and replication machinery in eukaryotic cells. ..
  3. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin L Hughes; Fiscal Year: 2010
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
  4. Gene Duplication and Genome Evolution
    Austin Hughes; Fiscal Year: 2004
    ..5) Examining the role of transposable elements in duplication of genomic segments by testing for nonrandom association between these elements and putatively duplicated blocks in the yeast genome. ..
  5. Highly Improved Bacterial Larvicides for Vector Control
    Brian Federici; Fiscal Year: 2007
    ..This collaboration has the common goal of having new products based on these recombinant bacteria on the market within five years, sooner if possible. ..
  6. Baculovirus envelope proteins and insect cells
    GARY BLISSARD; Fiscal Year: 2009
    ..In addition, results of many of these studies will be directly applicable to new and exciting biotechnological applications of baculoviruses in mammalian cells. ..
  7. Apoptosis as an anti-viral response in mosquito midgut
    ROLLIE CLEM; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  8. FUNCTIONAL ANALYSIS OF ANTIAPOPTOTIC IAP PROTEINS
    ROLLIE CLEM; Fiscal Year: 2002
    ....
  9. INTERACTION OF CLQ ON PHAGOCYTIC CELLS
    Andrea Joan Tenner; Fiscal Year: 2010
    ....
  10. Monotonously Ordered Peptide Elements
    Fred Stevens; Fiscal Year: 2008
    ..In general, the proposed studies are designed to begin to evaluate the prospects of future studies to determine the physiological roles of particular MOPE-class proteins. [unreadable] [unreadable] [unreadable]..