arboviruses

Summary

Summary: Arthropod-borne viruses. A non-taxonomic designation for viruses that can replicate in both vertebrate hosts and arthropod vectors. Included are some members of the following families: ARENAVIRIDAE; BUNYAVIRIDAE; REOVIRIDAE; TOGAVIRIDAE; and FLAVIVIRIDAE. (From Dictionary of Microbiology and Molecular Biology, 2nd ed)

Top Publications

  1. pmc Genome sequence of Aedes aegypti, a major arbovirus vector
    Vishvanath Nene
    Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 316:1718-23. 2007
  2. ncbi The global emergence/resurgence of arboviral diseases as public health problems
    Duane J Gubler
    Department of Health and Human Services, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Fort Collins, CO 80522, USA
    Arch Med Res 33:330-42. 2002
  3. pmc Biological transmission of arboviruses: reexamination of and new insights into components, mechanisms, and unique traits as well as their evolutionary trends
    Goro Kuno
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA
    Clin Microbiol Rev 18:608-37. 2005
  4. ncbi Larval environmental temperature and insecticide exposure alter Aedes aegypti competence for arboviruses
    Ephantus J Muturi
    Illinois Natural History Survey, University of Illinois, Champaign, Illinois 61820, USA
    Vector Borne Zoonotic Dis 11:1157-63. 2011
  5. ncbi Isolation of bovine arboviruses from Culicoides biting midges (Diptera: Ceratopogonidae) in southern Japan: 1985--2002
    T Yanase
    Kyushu Research Station, National Institute of Animal Health, Chuzan, Kagoshima, 891 0105 Japan
    J Med Entomol 42:63-7. 2005
  6. pmc First report in Italy of the exotic mosquito species Aedes (Finlaya) koreicus, a potential vector of arboviruses and filariae
    Gioia Capelli
    Istituto Zooprofilattico Sperimentale delle Venezie, Laboratory of Parasitology, Viale dell Universita 10, Legnaro, 35020, Italy
    Parasit Vectors 4:188. 2011
  7. pmc Arboviral encephalitides: transmission, emergence, and pathogenesis
    Bradley S Hollidge
    Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104 4283, USA
    J Neuroimmune Pharmacol 5:428-42. 2010
  8. pmc Fundamental issues in mosquito surveillance for arboviral transmission
    Weidong Gu
    Division of Infectious Diseases, University of Alabama, Birmingham, AL 35294, USA
    Trans R Soc Trop Med Hyg 102:817-22. 2008
  9. ncbi Culicoides biting midges: their role as arbovirus vectors
    P S Mellor
    Institute for Animal Health, Woking, Surrey, UK
    Annu Rev Entomol 45:307-40. 2000
  10. ncbi Mosquito (Diptera: Culicidae) surveillance for arboviruses in an area endemic for West Nile (Lineage Rabensburg) and Tahyna viruses in Central Europe
    Z Hubalek
    Institute of Vertebrate Biology, Academy of Sciences, Department of Medical Zoology, Klasterni 2, CZ 69142 Valtice, Czech Republic
    J Med Entomol 47:466-72. 2010

Detail Information

Publications225 found, 100 shown here

  1. pmc Genome sequence of Aedes aegypti, a major arbovirus vector
    Vishvanath Nene
    Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 316:1718-23. 2007
    ..An increase in genes encoding odorant binding, cytochrome P450, and cuticle domains relative to An. gambiae suggests that members of these protein families underpin some of the biological differences between the two mosquito species...
  2. ncbi The global emergence/resurgence of arboviral diseases as public health problems
    Duane J Gubler
    Department of Health and Human Services, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Fort Collins, CO 80522, USA
    Arch Med Res 33:330-42. 2002
    ....
  3. pmc Biological transmission of arboviruses: reexamination of and new insights into components, mechanisms, and unique traits as well as their evolutionary trends
    Goro Kuno
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA
    Clin Microbiol Rev 18:608-37. 2005
    Among animal viruses, arboviruses are unique in that they depend on arthropod vectors for transmission...
  4. ncbi Larval environmental temperature and insecticide exposure alter Aedes aegypti competence for arboviruses
    Ephantus J Muturi
    Illinois Natural History Survey, University of Illinois, Champaign, Illinois 61820, USA
    Vector Borne Zoonotic Dis 11:1157-63. 2011
    ..These results show that environmental factors, including those factors used in controlling mosquitoes, experienced by immature stages have latent effects that continue to adulthood and alter vector competence to arboviruses.
  5. ncbi Isolation of bovine arboviruses from Culicoides biting midges (Diptera: Ceratopogonidae) in southern Japan: 1985--2002
    T Yanase
    Kyushu Research Station, National Institute of Animal Health, Chuzan, Kagoshima, 891 0105 Japan
    J Med Entomol 42:63-7. 2005
    In 1985--2002, surveillance for bovine arboviruses was conducted in Kagoshima, located in the most southern part of the main islands of Japan and known to be an area where bovine arboviral diseases have frequently been epidemic...
  6. pmc First report in Italy of the exotic mosquito species Aedes (Finlaya) koreicus, a potential vector of arboviruses and filariae
    Gioia Capelli
    Istituto Zooprofilattico Sperimentale delle Venezie, Laboratory of Parasitology, Viale dell Universita 10, Legnaro, 35020, Italy
    Parasit Vectors 4:188. 2011
    ..During the routine monitoring activity in a tiger mosquito-free area, an unexpected mosquito was noticed, which clearly did not belong to the recorded Italian fauna...
  7. pmc Arboviral encephalitides: transmission, emergence, and pathogenesis
    Bradley S Hollidge
    Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104 4283, USA
    J Neuroimmune Pharmacol 5:428-42. 2010
    Arthropod-borne viruses (arboviruses) are of paramount concern as a group of pathogens at the forefront of emerging and re-emerging diseases...
  8. pmc Fundamental issues in mosquito surveillance for arboviral transmission
    Weidong Gu
    Division of Infectious Diseases, University of Alabama, Birmingham, AL 35294, USA
    Trans R Soc Trop Med Hyg 102:817-22. 2008
    Marked spatiotemporal variabilities in mosquito infection of arboviruses, exemplified by the transmission of West Nile virus (WNV) in America, require adaptive strategies for mosquito sampling, pool screening and data analyses...
  9. ncbi Culicoides biting midges: their role as arbovirus vectors
    P S Mellor
    Institute for Animal Health, Woking, Surrey, UK
    Annu Rev Entomol 45:307-40. 2000
    ..transmit a great number of assorted pathogens of human, and domestic and wild animals, but it is as vectors of arboviruses, and particularly arboviruses of domestic livestock, that they achieve their prime importance...
  10. ncbi Mosquito (Diptera: Culicidae) surveillance for arboviruses in an area endemic for West Nile (Lineage Rabensburg) and Tahyna viruses in Central Europe
    Z Hubalek
    Institute of Vertebrate Biology, Academy of Sciences, Department of Medical Zoology, Klasterni 2, CZ 69142 Valtice, Czech Republic
    J Med Entomol 47:466-72. 2010
    ..This species feeds mostly on mammals including man; this raises the question whether this virus lineage is not adapted to an alternative mosquito-mammal cycle in the South-Moravian natural focus...
  11. ncbi Sylvatic transmission of arboviruses among Bornean orangutans
    N D Wolfe
    Department of Immunology and Infectious Disease, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Am J Trop Med Hyg 64:310-6. 2001
    ..The present study demonstrates that orangutans are susceptible to arboviralinfections in the wild, although the impact of arboviral infections on this endangered ape remain unknown...
  12. ncbi Inadequate management of natural ecosystem in the Brazilian Amazon region results in the emergence and reemergence of arboviruses
    P F Vasconcelos
    World Health Organization Collaborating Center for Reference and Research on Arboviruses, Department of Arbovirus, Instituto Evandro Chagas, , , , PA, 66090-000, Brasil
    Cad Saude Publica 17:155-64. 2001
    A total of 187 different species of arboviruses and other viruses in vertebrates were identified at the Evandro Chagas Institute (IEC) from 1954 to 1998, among more than 10,000 arbovirus strains isolated from humans, hematophagous ..
  13. pmc Evolution of mosquito-based arbovirus surveillance systems in Australia
    Andrew F van den Hurk
    Public Health Virology, Communicable Diseases Unit, Queensland Health Forensic and Scientific Services, 39 Kessels Rd, Coopers Plains, Queensland 4108, Australia Andrew
    J Biomed Biotechnol 2012:325659. 2012
    ..within a box trap to probe a sugar-baited nucleic-acid preservation card that is processed for expectorated arboviruses. In a longitudinal field trial, both Ross River and Barmah Forest viruses were detected numerous times from ..
  14. pmc Exploiting mosquito sugar feeding to detect mosquito-borne pathogens
    Sonja Hall-Mendelin
    School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland 4072, Australia
    Proc Natl Acad Sci U S A 107:11255-9. 2010
    Arthropod-borne viruses (arboviruses) represent a global public health problem, with dengue viruses causing millions of infections annually, while emerging arboviruses, such as West Nile, Japanese encephalitis, and chikungunya viruses ..
  15. ncbi Short report: detection probability of arbovirus infection in mosquito populations
    Weidong Gu
    Illinois Natural History Survey, Medical Entomology Laboratory, 182 Natural Resources Building, 607 E Peabody Drive, Champaign, IL 61820, USA
    Am J Trop Med Hyg 71:636-8. 2004
    ..8) of detection. Due to focal transmission of arboviruses, grouping samples over different sampling sites and times is often inappropriate for detection of mosquito ..
  16. ncbi Transmission cycles, host range, evolution and emergence of arboviral disease
    Scott C Weaver
    Department of Pathology, Microbiology and Immunology, Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, Texas 77555 0609, USA
    Nat Rev Microbiol 2:789-801. 2004
    ..We discuss viruses of medical importance, including Venezuelan equine and Japanese encephalitis viruses, dengue viruses and West Nile viruses...
  17. pmc Aedes albopictus in Lebanon, a potential risk of arboviruses outbreak
    Nabil Haddad
    Institut Pasteur, Department of Virology, Arboviruses and Insect Vectors, 25 28 Rue du Dr Roux, 75724 Paris Cedex 15, France
    BMC Infect Dis 12:300. 2012
    The mosquito Aedes albopictus is undergoing a worldwide expansion with potential consequences on transmission of various arboviruses. This species has been first detected in Lebanon in 2003.
  18. pmc The role of interferon antagonist, non-structural proteins in the pathogenesis and emergence of arboviruses
    Bradley S Hollidge
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Viruses 3:629-58. 2011
    A myriad of factors favor the emergence and re-emergence of arthropod-borne viruses (arboviruses), including migration, climate change, intensified livestock production, an increasing volume of international trade and transportation, and ..
  19. ncbi Development of a rapid and comprehensive proteomics-based arboviruses detection system
    Kenta Okamoto
    Department of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852 8523, Japan
    J Virol Methods 167:31-6. 2010
    ..ionisation-tandem mass spectrometry (LC-ESI/MS/MS), was developed for identification of arboviruses in infected culture fluid...
  20. ncbi [Serological survey for arboviruses in Juruti, Pará State, Brazil]
    Ana Cecilia Ribeiro Cruz
    Seção de Arbovirologia e Febres Hemorrágicas, Instituto Evandro Chagas, Ananindeua, PA, Brazil
    Cad Saude Publica 25:2517-23. 2009
    This study aimed to measure the prevalence of antibodies to arboviruses in the area affected by the Juruti Project before local mining operations...
  21. ncbi [Serologic survey for yellow fever and other arboviruses among inhabitants of Rio Branco, Brazil, before and three months after receiving the yellow fever 17D vaccine]
    Jose Tavares-Neto
    Faculdade de Medicina, Universidade Federal da Bahia, Uberlandia, MG, Brazil
    Rev Soc Bras Med Trop 37:1-6. 2004
    ..campaign among residents of Rio Branco (Acre State), the frequency of HI antibodies to the most prevalent arboviruses in the Amazon region and to yellow fever virus was determined before and three months after immunization with ..
  22. ncbi Isolation of arboviruses from mosquitoes collected in northern Vietnam
    Juliet E Bryant
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA
    Am J Trop Med Hyg 73:470-3. 2005
    ..Surprisingly, no isolates of Japanese encephalitis (JE) virus were obtained. Isolation of Akabane virus, Oya virus, Getah virus, and Sagiyama virus is reported for the first time from Vietnam...
  23. ncbi Cost effectiveness of three arbovirus surveillance methods in northern California
    T W Scott
    Department of Entomology, University of California, Davis 95616, USA
    J Am Mosq Control Assoc 17:118-23. 2001
    ..Future research efforts should investigate the costs and surveillance efficiency of modifications in the frequency of specimen collection and the placement of chicken flocks and mosquito traps...
  24. ncbi Arboviruses associated with human disease in Australia
    R C Russell
    Department of Medical Entomology, University of Sydney, Institute of Clinical Pathology and Medical Research, Westmead Hospital, NSW 2145, Westmead, Australia
    Microbes Infect 2:1693-704. 2000
    Mosquito-borne arboviruses are an important public health issue in Australia. The alphaviruses Ross River and Barmah Forest virus are widespread and active annually, and cause debilitating polyarthritis...
  25. pmc Arbovirus detection in insect vectors by rapid, high-throughput pyrosequencing
    Kimberly A Bishop-Lilly
    Biological Defense Research Directorate, Naval Medical Research Center, Silver Spring, Maryland, USA
    PLoS Negl Trop Dis 4:e878. 2010
    ..Therefore, these techniques may be unsuitable for situations when the causative agent of an outbreak is unknown...
  26. ncbi Potential mosquito vectors of arboviruses in Portugal: species, distribution, abundance and West Nile infection
    A P G Almeida
    Unidade de Parasitologia e Microbiologia Médicas, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, R Junqueira 96, 1349 008 Lisboa, Portugal
    Trans R Soc Trop Med Hyg 102:823-32. 2008
    ..The density and proximity of these mosquitoes to the human populations may constitute a public health threat in the case of involvement in arbovirus transmission cycles...
  27. ncbi Transmission of arboviruses without involvement of arthropod vectors
    G Kuno
    Arbovirus Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80522 2087, USA
    Acta Virol 45:139-50. 2001
    Transmission of arboviruses (arthropod-borne viruses belonging to various virus families) without involvement of arthropod vectors has been documented for years, but the reports have not been reviewed systematically...
  28. ncbi Emergent arboviruses in Brazil
    Luiz Tadeu Moraes Figueiredo
    Centro de Pesquisa em Virologia, Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo, Ribeirao Preto, SP, Brazil
    Rev Soc Bras Med Trop 40:224-9. 2007
    ..These provide ideal conditions for the existence of many arboviruses, which are maintained in a large variety of zoonotic cycles...
  29. pmc Potential arbovirus emergence and implications for the United Kingdom
    Ernest Andrew Gould
    Centre for Ecology and Hydrology Oxford, Oxford, UK
    Emerg Infect Dis 12:549-55. 2006
    b>Arboviruses have evolved a number of strategies to survive environmental challenges...
  30. pmc Tickborne arbovirus surveillance in market livestock, Nairobi, Kenya
    Rosemary Sang
    Kenya Medical Research Institute, Nairobi, Kenya
    Emerg Infect Dis 12:1074-80. 2006
    ..Our results demonstrate the potential for tickborne dissemination of endemic and emergent viruses and the relevance of A. gemma in the maintenance of tickborne viruses in this region...
  31. ncbi Tick-borne viruses
    M Labuda
    Institute of Zoology, Slovak Academy of Sciences, Dubravska cesta 9, 845 06 Bratislava, Slovakia
    Parasitology 129:S221-45. 2004
    ..specific and less than 10% of all tick species (Argasidae and Ixodidae) are known to play a role as vectors of arboviruses. However, a few tick species transmit several (e.g. Ixodes ricinus, Amblyomma variegatum) or many (I...
  32. pmc Mosquitoes and mosquito-borne arboviruses in the Qinghai-Tibet Plateau--focused on the Qinghai area, China
    Wen Juan Li
    Department of Virology, School of Public Health, Shandong University, The Key Laboratory of Experimental Teratology, Ministry of Education, Jinan, China
    Am J Trop Med Hyg 82:705-11. 2010
    An investigation was conducted to identify the distribution of mosquitoes and mosquito-borne arboviruses in the Qinghai-Tibet Plateau, China from July to August in 2007...
  33. ncbi Arbovirus surveillance of mosquitoes collected at sites of active Rift Valley fever virus transmission: Kenya, 2006-2007
    Mary Crabtree
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, U S Department of Health and Human Services, 3150 Rampart Road, Foothills Campus, Fort Collins, CO 80521, USA
    J Med Entomol 46:961-4. 2009
    ..of Rift Valley fever in Kenya from December 2006 to February 2007 were tested to isolate other mosquito-borne arboviruses circulating in the region...
  34. ncbi Arboviruses isolated from mosquitoes collected from urban and peri-urban areas of eastern Australia
    Cassie C Jansen
    Australian Biosecurity Cooperative Research Centre for Emerging Infectious Disease, University of Queensland, St Lucia, Australia
    J Am Mosq Control Assoc 25:272-8. 2009
    To determine the presence of arboviruses in mosquito populations from major urban areas of eastern Australia, a total of 67,825 mosquitoes, representing -60 species, was collected and tested from Cairns, Brisbane, and Sydney between ..
  35. pmc Possible ecology and epidemiology of medically important mosquito-borne arboviruses in Great Britain
    J M Medlock
    Health Protection Agency, Centre for Emergency Preparedness and Response, Porton Down, Salisbury, Wiltshire, UK
    Epidemiol Infect 135:466-82. 2007
    Nine different arboviruses are known to be transmitted by, or associated with, mosquitoes in Europe, and several (West Nile, Sindbis and Tahyna viruses) are reported to cause outbreaks of human disease...
  36. ncbi Seroprevalence and distribution of Flaviviridae, Togaviridae, and Bunyaviridae arboviral infections in rural Cameroonian adults
    Mark H Kuniholm
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Am J Trop Med Hyg 74:1078-83. 2006
    b>Arboviruses from the families Flaviviridae, Togaviridae, and Bunyaviridae are suspected to cause widespread morbidity in sub-Saharan African populations, but little research been done to document the burden and distribution of these ..
  37. ncbi Geographical distribution of arboviruses in Yugoslavia
    J Vesenjak-Hirjan
    Department of Virology, A Stamper School of Public Health, Medical Faculty University of Zagreb, Yugoslavia
    J Hyg Epidemiol Microbiol Immunol 35:129-40. 1991
    Studies of arboviruses started in Yugoslavia in 1953 following the isolation of TBE virus which caused a severe epidemic that year...
  38. ncbi Establishment and characterization of a new continuous cell line from Lutzomyia longipalpis (Diptera: psychodidae) and its susceptibility to infections with arboviruses and Leishmania chagasi
    G J Rey
    Laboratorios de Virología y Entomología, Instituto Nacional de Salud, Santafe de Bogota, D C, Colombia
    Mem Inst Oswaldo Cruz 95:103-10. 2000
    ..Lulo was free from bacterial, fungal, mycoplasmic and viral infection. Susceptibility to five arbovirus was determined, the same as Lulo interaction with Leishmania promastigotes...
  39. ncbi Seroprevalence of five arboviruses in Zebu cattle in the Central African Republic
    J M Guilherme
    Association Nationale pour le Développement de l Elevage, Bangui, Republique Centrafricaine
    Trans R Soc Trop Med Hyg 90:31-3. 1996
    ..Antibodies to RVF virus were found in about 8% of adult cattle. Zebus do not play an important role in the spread of CHIK and WSL viruses among humans; these viruses were found in only one and 5, respectively, of the 183 cattle examined...
  40. pmc Arbovirus of marine mammals: a new alphavirus isolated from the elephant seal louse, Lepidophthirus macrorhini
    M La Linn
    Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research and the University of Queensland, Brisbane, Queensland, Australia
    J Virol 75:4103-9. 2001
    ..The SES virus represents the first arbovirus of marine mammals and illustrates that alphaviruses can inhabit Antarctica and that alphaviruses can be transmitted by lice...
  41. ncbi Isolation of viruses from mosquitoes (Diptera: Culicidae) collected in the Amazon Basin region of Peru
    M J Turell
    Virology Division, U S Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Fort Detrick, MD 21702 5011, USA
    J Med Entomol 42:891-8. 2005
    ..in the Amazon Basin region of Peru, we assayed 539,694 mosquitoes captured in Loreto Department, Peru, for arboviruses. Mosquitoes were captured either by dry ice-baited miniature light traps or with aspirators while mosquitoes ..
  42. pmc Arbovirus evolution in vivo is constrained by host alternation
    Lark L Coffey
    Department of Pathology and Center for Tropical Diseases, University of Texas Medical Branch, Galveston, TX 77555, USA
    Proc Natl Acad Sci U S A 105:6970-5. 2008
    ..processes promoting cross-species transfers are poorly defined, especially for arthropod-borne viruses (arboviruses)...
  43. ncbi Distribution of arboviruses and mosquitoes in northwestern Yunnan Province, China
    Xiaohong Sun
    State Key Laboratory for Infectious Disease Prevention and Control, Institute for Viral Disease Control and Prevention, China CDC, Beijing, China
    Vector Borne Zoonotic Dis 9:623-30. 2009
    From July to September in 2005 and 2006, a survey was conducted to identify mosquito species and mosquito-borne arboviruses at elevations ranging from 900-3280 m between 24 degrees 00' N and 29 degrees 00' N latitude in the northwestern ..
  44. ncbi Arboviruses in Italy
    L Nicoletti
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    Parassitologia 50:109-11. 2008
    A brief review of the arboviruses isolated In Italy is presented and discussed...
  45. pmc Application of modified shell vial culture procedure for arbovirus detection
    Edna R Caceda
    American Embassy, Naval Medical Research Center Detachment, Lima, Peru
    PLoS ONE 2:e1034. 2007
    The isolation of arboviruses from patient's low titer sera can be difficult...
  46. pmc Genetic and fitness changes accompanying adaptation of an arbovirus to vertebrate and invertebrate cells
    S C Weaver
    Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555, USA
    J Virol 73:4316-26. 1999
    The alternating host cycle and persistent vector infection may constrain the evolution of arboviruses. To test this hypothesis, eastern equine encephalitis virus was passaged in BHK or mosquito cells, as well as in alternating (both) ..
  47. ncbi Lack of evolutionary stasis during alternating replication of an arbovirus in insect and mammalian cells
    I S Novella
    Department of Biology and Institute for Molecular Genetics, University of California San Diego, La Jolla, CA, USA
    J Mol Biol 287:459-65. 1999
    ..Thus, the slow rates of evolution observed in natural populations of arboviruses are not necessarily due to the need for the virus to compromise between adaptation to both arthropod and ..
  48. ncbi [Tick-transmitted arbovirus in Maghreb]
    C Chastel
    Laboratoire de Virologie, Faculte de Medecine, Brest, France
    Bull Soc Pathol Exot 88:81-5. 1995
    ..Four tick-borne arboviruses have been isolated so far: three from Morocco, Soldado (Nairovirus), Essaouria (Orbivirus) and Kala Iris (..
  49. ncbi Arboviruses causing neurological disorders in the central nervous system
    G Dobler
    Max von Pettenkofer Institute for Hygiene and Medical Microbiology, , Munich, Federal Republic of Germany
    Arch Virol Suppl 11:33-40. 1996
    ..In addition to the tick-borne encephalitis viruses, other arboviruses in Europe are known to cause neurological disorders...
  50. ncbi Infection by certain arboviruses among workers potentially at risk of infection
    A Nagwa
    Water Pollution Dept, National Research Centre, Cairo-Egypt
    J Egypt Public Health Assoc 76:169-82. 2001
    ..38%) and 3 persons for SIN viruses. Out of the four STPs Helwan workers' exhibited the highest infection rate for most of the studied arboviruses WN, SFN, SIN and SFS.
  51. ncbi Isolation of arboviruses from mosquitoes (Diptera: Culicidae) collected from the Gulf Plains region of northwest Queensland, Australia
    A F Van Den Hurk
    Department of Microbiology and Parasitology, School of Molecular and Microbial Sciences, University of Queensland, St Lucia, Australia
    J Med Entomol 39:786-92. 2002
    ..The isolate of RR from Ae. lineatopennis was the first reported from this species. The public health implications of these isolations in the Gulf Plains region are discussed briefly...
  52. ncbi Arboviruses and their vectors in the Pacific--status report
    Laurent Guillaumot
    Entomology Unit, New Caledonia Pasteur Institute
    Pac Health Dialog 12:45-52. 2005
    Three arboviruses have already caused epidemics in various Pacific Island countries and territories, and currently represent a direct threat to public health...
  53. pmc Seroepidemiology of arboviruses among seabirds and island residents of the Great Barrier Reef and Coral Sea
    I Humphery-Smith
    Department of Parasitology, University of Queensland, St Lucia, Australia
    Epidemiol Infect 107:435-40. 1991
    ..sera from island residents collected in the Coral Sea and on Australia's Great Barrier Reef against 19 known arboviruses. Antibodies to a potentially harmful flavivirus, Gadget's Gully virus, were equally present (4%) in both avian ..
  54. ncbi Influence of nonsystemic transmission on the epidemiology of insect borne arboviruses: a case study of vesicular stomatitis epidemiology in the western United States
    Cynthia C Lord
    Florida Medical Entomology Laboratory, University of Florida, IFAS, Vero Beach 32962, USA
    J Med Entomol 39:417-26. 2002
    ..The data needed to compare the two pathways and their relative roles in virus epidemiology are discussed...
  55. ncbi Simultaneous detection of bovine arboviruses using single-tube multiplex reverse transcription-polymerase chain reaction
    Seiichi Ohashi
    Kyushu Research Station, National Institute of Animal Health, 2702 Chuzan, Kagoshima 891 0105, Japan
    J Virol Methods 120:79-85. 2004
    ..multiplex reverse transcription-polymerase chain reaction (mRT-PCR) assay was developed to detect and identify arboviruses in infected cell-culture fluids and field specimens...
  56. ncbi Universal diagnostic RT-PCR protocol for arboviruses
    G Kuno
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80522 2087, USA
    J Virol Methods 72:27-41. 1998
    ..were evaluated to determine if they could serve as a universal protocol for detecting and identifying all arboviruses. In this study, four parameters that affect the efficacy of RT-PCR (RNA extraction method, choice of reverse ..
  57. ncbi [Circulation of West Nile virus (Flaviviridae, Flavivirus) and some other arboviruses in the ecosystems of Volga delta, Volga-Akhtuba flood-lands and adjoining arid regions (2000-2002)]
    D K L'vov
    Vopr Virusol 49:45-51. 2004
    ..serological as well as genetic studies of the ecology of West Nile Virus (WNV) as well as of some other arboviruses were undertaken in different ecosystems in the territories of the Astrakhan Region and of the Kalmyk Republic...
  58. pmc Ticks associated with macquarie island penguins carry arboviruses from four genera
    Lee Major
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    PLoS ONE 4:e4375. 2009
    ..Macquarie Island penguins thus harbour arboviruses from at least four of the seven arbovirus-containing genera, with related viruses often found in the northern ..
  59. ncbi Persistence of arboviruses and antiviral antibodies in vertebrate hosts: its occurrence and impacts
    G Kuno
    Arbovirus Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA
    Rev Med Virol 11:165-90. 2001
    ..in New York immediately raised, as one of a few explanations, the possibility of long-term persistence of arboviruses in vertebrate hosts...
  60. ncbi Aedes (Diptera: Culicidae) vectors of arboviruses in Mayotte (Indian Ocean): distribution area and larval habitats
    Leïla Bagny
    CIRAD, UMR Peuplement des Végétaux et Bio agresseur en Milieu Tropical CIRAD Université de la Réunion, Pôle de Protection des Plantes 3P, 7 chemin de l IRAT, 97410 Saint Pierre, La Reunion, France
    J Med Entomol 46:198-207. 2009
    ..Thus, arbovirus surveillance programs should focus, as a priority, on areas where this vector is present because of a higher risk of emergence of an epidemic source of arboviruses.
  61. pmc Relationships between host viremia and vector susceptibility for arboviruses
    Cynthia C Lord
    Florida Medical Entomology Laboratory, University of Florida IFAS, Vero Beach 32962, USA
    J Med Entomol 43:623-30. 2006
    ..Relying on assumptions with little support may result in erroneous conclusions about the importance of different hosts...
  62. ncbi [Serological monitoring of arbovirus infections in the estuary of the Kuban River (the 2006-2007 data)]
    D K L'vov
    Vopr Virusol 53:30-5. 2008
    ..The findings suggest the presence of arboviruses from 6 transmitting mosquitoes and ticks in the study area and human infection by the viruses of the antigenic ..
  63. ncbi Investigator profile. Interview with Charles H. Calisher, Ph.d. Interview by Vicki Glaser
    Charles H Calisher
    Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA
    Vector Borne Zoonotic Dis 5:212-7. 2005
  64. ncbi Amplification due to spatial clustering in an individual-based model of mosquito-avian arbovirus transmission
    Jeffrey Shaman
    College of Oceanic and Atmospheric Sciences, Oregon State University, 104 COAS Admin Building, Corvallis, OR 97331, USA
    Trans R Soc Trop Med Hyg 101:469-83. 2007
    ..indicate that spatial clustering of birds and mosquitoes may be necessary for epizootic amplification of arboviruses with avian zoonoses...
  65. pmc Intensive early season adulticide applications decrease arbovirus transmission throughout the Coachella Valley, Riverside County, California
    Hugh D Lothrop
    Arbovirus Research Unit, Center for Vectorborne Diseases, School of Veterinary Medicine, University of California, Davis, California 95616, USA
    Vector Borne Zoonotic Dis 8:475-89. 2008
    ..tarsalis abundance and delay of WNV activity in the rural lower valley and a marked decline in transmission by Culex quinquefasciatus Say populations in the densely populated upper northwestern valley with no human cases reported...
  66. ncbi Veterinarians refine new arbovirus diagnostic tools
    Mark Thornley
    Aust Vet J 83:246. 2005
  67. pmc Serological evidence of arboviral infection and self-reported febrile illness among U.S. troops deployed to Al Asad, Iraq
    M S Riddle
    Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    Epidemiol Infect 136:665-9. 2008
    ..Self-reported febrile illness was uncommon although often debilitating, and the risk of illness due to arbovirus infections was relatively low...
  68. ncbi Arbovirus surveillance in South Carolina, 1996-98
    A Wozniak
    South Carolina Department of Health and Environment Control, Columbia 29223, USA
    J Am Mosq Control Assoc 17:73-8. 2001
    b>Arboviruses isolated and identified from mosquitoes in South Carolina (USA) are described, including new state records for eastern equine encephalitis virus (EEE), St...
  69. ncbi Introduction and establishment of Aedes (Finlaya) Japonicus japonicus (Theobald) on the island of Hawaii: implications for arbovirus transmission
    Linda Burnham Larish
    Vector Control Branch, Hawaii State Department of Health, Hilo, Hawaii 96720, USA
    J Am Mosq Control Assoc 21:318-21. 2005
    ..Aedes (Fin.) j. japonicus is a competent laboratory vector for a number of arboviruses. Increased quarantine inspections, inspection and treatment of imported used tires and plants, disinsection of ..
  70. pmc Habitat segregation of mosquito arbovirus vectors in south Florida
    Jorge R Rey
    University of Florida, Institute of Food and Agricultural Sciences, Florida Medical Entomology Laboratory, 200 9th Street S E Vero Beach, FL 32962, USA
    J Med Entomol 43:1134-41. 2006
    ..aegypti and Ae. albopictus...
  71. ncbi [Brazil, land of choice for arbovirosis?]
    F Bedin
    bioMerieux, Tour CERVI, Lyon, France
    Med Trop (Mars) 67:281-7. 2007
    ..Currently yellow fever and especially dengue fever are major public health problems...
  72. ncbi Comparative attractiveness of two chicken breeds to mosquitoes in southern California
    Rosalie T Trevejo
    Western University of Health Sciences, College of Veterinary Medicine, 309 East Second Street, Pomona, CA 91766 1854, USA
    J Am Mosq Control Assoc 22:37-41. 2006
    ..Larger sample sizes or experimental infection of different chicken breeds may identify differences in their response to arbovirus infection...
  73. pmc Global traffic and disease vector dispersal
    Andrew J Tatem
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom
    Proc Natl Acad Sci U S A 103:6242-7. 2006
    ..framework to describe the historical spread of Aedes albopictus, a competent mosquito vector of 22 arboviruses in the laboratory...
  74. ncbi Evolutionary influences in arboviral disease
    S C Weaver
    Center for Biodefense and Emerging Infectious Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555 0609, USA
    Curr Top Microbiol Immunol 299:285-314. 2006
    Arthropod-borne viruses (arboviruses) generally require horizontal transmission by arthropod vectors among vertebrate hosts for their natural maintenance...
  75. ncbi Rodent and arthropod-borne viral zoonoses in Northern Europe
    Olli Vapalahti
    Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine and Department of Virology, Haartman Institute, University of Helsinki, Finland
    Acta Vet Scand Suppl 100:69-71. 2003
  76. ncbi [Arboviruses and epizootic viruses]
    Vincent Deubel
    Unité de Biologie des Infections Virales Emergentes, Institut Pasteur, 21, Avenue Tony Garnier, 69365 Lyon, France
    C R Biol 325:855-61; discussion 879-83. 2002
    ..Among more than 500 arboviruses and epizootic viruses that are classified into seven families, only a few are responsible for zoonoses or cause ..
  77. ncbi [Infections due to Toscana virus, West Nile virus, and other arboviruses of interest in Europe]
    Mari Paz Sánchez-Seco
    Laboratorio de Arbovirus y Enfermedades Víricas Importadas, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain
    Enferm Infecc Microbiol Clin 23:560-8. 2005
    ..To achieve an accurate diagnosis, high clinical suspicion is required as well as highly specific laboratory techniques, mainly based on IgM detection, RT-PCR and viral culture of CSF and/or serum...
  78. ncbi Host-plant viral infection effects on arthropod-vector population growth, development and behaviour: management and epidemiological implications
    J Colvin
    Natural Resources Institute, University of Greenwich, Central Avenue Chatham Maritime, Chatham, Kent ME4 4TB, United Kingdom
    Adv Virus Res 67:419-52. 2006
  79. ncbi Arbovirus circulation, temporal distribution, and abundance of mosquito species in two Carolina bay habitats
    D I Ortiz
    Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0609, USA
    Vector Borne Zoonotic Dis 5:20-32. 2005
    ..The study of mosquito and arbovirus ecology in Carolina Bay habitats could provide more information on the transmission dynamics of arboviruses and its impact on human and animal arboviral disease occurrence in South Carolina.
  80. ncbi Necropsy findings and arbovirus surveillance in mourning doves from the southeastern United States
    Richard W Gerhold
    Southeastern Cooperative Wildlife Disease Study, College of Veterinary Medicine, University of Georgia, Athens, Georgia 30602, USA
    J Wildl Dis 43:129-35. 2007
    ..West Nile virus was isolated from 2.1% (n = 17) and eastern equine encephalitis virus (EEEV) was isolated from 0.2% (n = 2) of the submitted birds...
  81. ncbi [Anti-arboviral properties of different substances of chemical and plant origin]
    I A Vynograd
    Lviv Scientific-Research Institute of Epidemiology and Hygiene, Ministry of Public Health of Ukraine, 12 Zelena St, Lviv, 79005, Ukraine
    Mikrobiol Z 63:14-9. 2001
    ....
  82. ncbi The host complement system and arbovirus pathogenesis
    T E Morrison
    Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Curr Drug Targets 9:165-72. 2008
    Arthropod-borne viruses (arboviruses) are a significant cause of human diseases worldwide. Interactions between these viruses and the innate immune system play a major role in determining the outcome of disease...
  83. ncbi Bird movement predicts Buggy Creek virus infection in insect vectors
    Charles R Brown
    Department of Biological Sciences, University of Tulsa, Tulsa, OK 74104, USA
    Vector Borne Zoonotic Dis 7:304-14. 2007
    ....
  84. ncbi Distribution of three arbovirus antibodies among monkeys (Macaca fascicularis) in the Philippines
    S Inoue
    Department of Virology, Institute of Tropical Medicine, Nagasaki University, 1 12 4 Sakamoto, Nagasaki City, Nagasaki 852 8523, Japan
    J Med Primatol 32:89-94. 2003
    ..These findings suggest possible sylvatic transmission cycles of these viruses...
  85. ncbi Initiating arbovirus surveillance in Arkansas, 2001
    Rebekah J Kent
    Department of Entomology, University of Arkansas, Fayetteville, AR 72701, USA
    J Med Entomol 40:223-9. 2003
    ..was to establish a cooperative arbovirus surveillance program to monitor mosquitoes and birds in Arkansas for arboviruses. Our objectives were to: 1) perform routine, multicounty collections of mosquitoes and test them for eastern ..
  86. ncbi Control of arbovirus vector Verrallina funerea (Diptera: Culicidae) in southeast Queensland, Australia
    Jason A L Jeffery
    Queensland Institute of Medical Research and University of Queensland, Australian Centre for International and Tropical Health, PO Royal Brisbane Hospital, QLD 4029, Australia
    J Econ Entomol 100:1512-8. 2007
    ..We also observed a significant increase in immature mortality in s-methoprene-treated pools, suggesting that s-methoprene field trials based solely on emergence inhibition of pupae may underestimate the efficacy of this insecticide...
  87. ncbi The Chikungunya threat: an ecological and evolutionary perspective
    Christine Chevillon
    Génétique et Evolution des Maladies Infectieuses UMR CNRS IRD 2724, Centre IRD, 911 Avenue Agropolis, BP 64501 F 34095 Montpellier CEDEX 5, France
    Trends Microbiol 16:80-8. 2008
    ..also emerged when comparing the evolution of Dengue-related (Flaviviruses) and of CHIKV-related (Alphaviruses) arboviruses. In this review, we discuss current information on CHIKV genetics, ecology and human infection...
  88. ncbi Temporal abundance, parity, survival rates, and arbovirus isolation of field-collected container-inhabiting mosquitoes in eastern Tennessee
    Kristy L Gottfried
    Division of Vector Borne Infectious Diseases, National Center for Infectious Disease, Centers for Disease Control and Prevention, Fort Collins, CO 80522, USA
    J Am Mosq Control Assoc 18:164-72. 2002
    ..albopictus and from Tennessee, as well as the 1st time this potential human pathogen has been isolated from transovarially infected field populations of Ae. albopictus...
  89. ncbi [Anti-arbovirus antibodies positive serum screening in population of Saratov]
    S A Shcherbakova
    Vopr Virusol 47:32-4. 2002
    ..Screening of 218 sera showed that the stratum immune to arboviruses increased from 1998 to 2000. The incidence of antibodies to Batai and Sindbis viruses was the highest...
  90. ncbi Arboviral infection in two species of wild jays (Aves: Corvidae): evidence for population impacts
    Mary C Garvin
    Archbold Biological Station, 123 Main Dr, Venus, FL 33960, USA
    J Med Entomol 41:215-25. 2004
    We examined the prevalence of antibodies to three mosquito-borne arboviruses in blue jays, Cyanocitta cristata, and Florida scrub-jays, Aphelocoma coerulescens, to identify the effects on host survival, the influence of sex and age on ..
  91. pmc Mosquito and arbovirus activity during 1997-2002 in a wetland in northeastern Mississippi
    E W Cupp
    Department of Entomology and Plant Pathology, 301 Funchess Hall, Auburn University, AL 36849 5413, USA
    J Med Entomol 41:495-501. 2004
    ..over a 6-yr period (1997-2002) and reverse transcription-polymerase chain reaction (PCR) detection rates of arboviruses determined during five of those years...
  92. pmc Emerging and nonemerging arboviral diseases and the veterinary/public health interface
    Harvey Artsob
    National Microbiology Laboratory, Health Canada, Manitoba
    Can Vet J 45:1021-2. 2004
  93. ncbi [Risk of arbovirus transmission by ticks in Thailand]
    J P Cornet
    Laboratoire d Acarologie, Center for Vectors and Vector Borne Diseases, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand
    Med Trop (Mars) 64:43-9. 2004
    ..based on a study of tick fauna in the central plain area of Thailand and on current knowledge about tick-borne arboviruses in Asia...
  94. ncbi A survey of the relationships among the viruses not considered arboviruses, vertebrates, and arthropods
    G Kuno
    Arbovirus Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, P O Box 2087, Fort Collins, CO 80522 2087, USA
    Acta Virol 48:135-43. 2004
    ..Compared with the well-recognized relationship found in arboviruses, however, most of the atypical arthropod-vertebrate relationships of the viruses normally not considered ..
  95. ncbi A very brief history of arbovirology, focusing on contributions by workers of the Rockefeller foundation
    Charles H Calisher
    Arthropod Borne and Infectious Diseases Laboratory, Colorado State University, Fort Collins, Colorado, USA
    Vector Borne Zoonotic Dis 5:202-11. 2005
  96. ncbi Critical review of the vector status of Aedes albopictus
    N G Gratz
    Med Vet Entomol 18:215-27. 2004
    ..albopictus is a competent vector for at least 22 arboviruses), notably dengue (all four serotypes) more commonly transmitted by Aedes (Stegomyia) aegypti (L.)...
  97. pmc A curious coincidence: mosquito biodiversity and the limits of the Japanese encephalitis virus in Australasia
    Stephane Hemmerter
    Institute for the Biotechnology of Infectious Diseases, University of Technology, Sydney, New South Wales, Australia
    BMC Evol Biol 7:100. 2007
    The mosquito Culex annulirostris Skuse (Diptera: Culicidae) is the major vector of endemic arboviruses in Australia and is also responsible for the establishment of the Japanese encephalitis virus (JEV) in southern Papua New Guinea (PNG) ..
  98. pmc Recent rapid rise of a permethrin knock down resistance allele in Aedes aegypti in México
    Gustavo Ponce Garcia
    Laboratorio de Entomologia Medica, Facultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, San Nicolas de los Garza, Nuevo Leon, Mexico
    PLoS Negl Trop Dis 3:e531. 2009
    ..aegypti remains the primary option to prevent and control outbreaks of the diseases caused by these arboviruses. Permethrin is one of the most widely used active ingredients in insecticides for suppression of adult Ae...
  99. ncbi [Epidemiology of encephalitis caused by arbovirus in the Brazilian Amazonia]
    P F Vasconcelos
    Instituto Evandro Chagas, Centro Colaborador da OMS em Arboviroses, Fundação SESP, Belem, Para, Brasil
    Rev Inst Med Trop Sao Paulo 33:465-76. 1991
    ..were the highways and projects of development, as well as places where outbreaks of human diseases caused by arboviruses had been detected...
  100. ncbi Serologic evidence of the recent circulation of Saint Louis encephalitis virus and high prevalence of equine encephalitis viruses in horses in the Nhecolândia sub-region in South Pantanal, Central-West Brazil
    Alex Pauvolid-Corrêa
    Laboratorio de Enterovirus, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, RJ, Brazil
    Mem Inst Oswaldo Cruz 105:829-33. 2010
    As in humans, sub-clinical infection by arboviruses in domestic animals is common; however, its detection only occurs during epizootics and the silent circulation of some arboviruses may remain undetected...
  101. ncbi Vector competence of selected African mosquito (Diptera: Culicidae) species for Rift Valley fever virus
    Michael J Turell
    Virology Division, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702 5011, USA
    J Med Entomol 45:102-8. 2008
    ..We did not recover RVFV from any of 3,138 progeny of infected female mosquitoes. RVFV is unusual among arboviruses in that it has been isolated in nature from a large number of species and that numerous mosquitoes and other ..

Research Grants62

  1. Genomics of Antiviral Responses of Anopheles gambiae Against O'nyong-nyong Virus
    Young S Hong; Fiscal Year: 2010
    ..b>Arboviruses transmitted by mosquito vectors are of great public health concern worldwide. For example, in the U.S...
  2. Novel Therapeutics for Neurotropic Alphaviruses
    David J Miller; Fiscal Year: 2013
    ..develop effective and broadly active therapies for encephalitis caused by neurotropic alphaviruses and related arboviruses. The specific aims of this proposal are: (1) targeted chemical modification of lead antiviral compounds, based ..
  3. Pathogenesis of Subtype IE Venezuelan Equine Encephalitis Virus
    ALISON PAIGE ADAMS; Fiscal Year: 2012
    ..Medical Branch (UTMB), has superb facilities and equipment and outstanding faculty who study various aspects of arboviruses, including comparative medicine, immunology, and vaccine development...
  4. Multiplex Serodiagnostic Protein Microarray
    PHILIP LOUIS FELGNER; Fiscal Year: 2012
    ..We will also fabricate a chip containing 190 proteins from 16 arboviruses and 8 hantaviruses...
  5. VEE Virus Infection on the Mosquito Vector
    Scott C Weaver; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The efficiency of mosquito infections by arthropod-borne viruses (arboviruses) can be an important determinant of disease emergence...
  6. Mechanisms of sylvatic dengue emergence
    Scott C Weaver; Fiscal Year: 2011
    ..applicant): A central goal of our research is to understand the mechanisms that enable arthropod-borne viruses (arboviruses) to emerge from sylvatic, zoonotic cycles into circulation among humans, thereby causing endemic or epidemic ..
  7. Metagenomic detection of emerging viruses in the blood supply
    Eric L Delwart; Fiscal Year: 2013
    ..The recent emergence of HIV, arboviruses such as WNV, DENV, and ChikV, as well as other highly pathogenic viruses, indicates that still uncharacterized ..
  8. Identification and evaluation of novel therapeutic targets for virus-induced neur
    Kenneth L Tyler; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Viral encephalitis, including encephalitis induced by the arboviruses West Nile virus (WNV) and Japanese encephalitis virus (JEV), is a major source of morbidity and mortality both in the U.S...
  9. Does Dengue Virus Suppress RNA Interference in its Mosquito Vector?
    KATHRYN ALYCE HANLEY; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Arthropod-borne viruses (arboviruses) face a two-fold challenge in countering the antiviral defenses of both vertebrate hosts and arthropod vectors...
  10. Diapause in Culex Mosquitoes
    David W Severson; Fiscal Year: 2013
    ..complex are primary vectors for the lymphatic filarioid nematode parasite, Wuchereria bancrofti and several arboviruses. This includes the recently introduced West Nile virus in North America...
  11. The Role of RNA Interference in West Nile Virus Diversification
    Douglas E Brackney; Fiscal Year: 2010
    Our long-term objectives are to understand the evolution of arboviruses in the context of their transmission cycles and how this impacts viral emergence, adaptation and persistence...
  12. Developing Anti-viral Ribozymes to Suppress Arboviruses in Transgenic Mosquitoes
    Malcolm J Fraser; Fiscal Year: 2013
    ..Interference with the incubation arboviruses within the arthropod vector is receiving considerable attention as a way to interrupt the viral transmission ..
  13. Arbovirus midgut escape mechanisms
    A Lorena Passarelli; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Arboviruses cause a significant world-wide health burden, with well over 100 million people becoming infected each year with viruses such as dengue, West Nile, yellow fever, and chikungunya, among ..
  14. Modulation of arboviruses in mosquitoes
    Kevin M Myles; Fiscal Year: 2012
    ..Maintenance of arboviruses in nature requires a biological transmission cycle that involves alternating virus replication in a susceptible ..
  15. Antiviral Pathways in Disease Vector Mosquitoes
    Zach N Adelman; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Arthropod-borne viruses (arboviruses) constitute a persistent and worldwide challenge to public health...
  16. CIRCADIAN REGULATION OF INNATE IMMUNE MECHANISMS OF VIRAL RECOGNITION
    Erol Fikrig; Fiscal Year: 2010
    ..g., activity, feeding, behavioral rhythms) and/or, in the case of arboviruses, the activity/biting rhythms of the vector carrying the virus...
  17. Developing Transgenic Sindbis Virus as a Tool to Trace Neural Circuitry
    THOMAS ROBERT CLANDININ; Fiscal Year: 2013
    ..b>Arboviruses, viruses that infect both insect and mammalian hosts, represent some of the most common causes of viral ..
  18. Biological vector control reducing arboviruses, including Dengue and Chikungunya
    JAMES WILLIAM MAINS; Fiscal Year: 2012
    ..A regulatory pathway is defined. Moreover, the approach will be broadly applicable to additional mosquito vector species (e.g., Ae. aegypti, Culex pipiens, etc.) and appropriate for areas outside the USA. ..
  19. Quasispecies dynamics in arbovirus persistence emergence and fitness
    GREGORY DAVID EBEL; Fiscal Year: 2013
    ..Local, site-specific characteristics largely control the transmission dynamics of arthropod-borne viruses (arboviruses)...
  20. Integrated polymer microfluidic device for multiplex diagnosis of viral infection
    Robert G Ulrich; Fiscal Year: 2013
    ..diagnosis of infections caused by two pathogen groups with the greatest potential impact on public health: arboviruses (Japanese Encephalitis, Chikungunya, Dengue, Yellow Fever and others) and filoviruses (Ebola, Marburg)...
  21. Dissecting the alphavirus entry receptor NRAMP
    Sara Cherry; Fiscal Year: 2013
    ..Our central hypothesis is that dissecting the interactions of these medically important arboviruses with their receptor will reveal mechanisms that will aid in the development of antiviral treatments against ..
  22. The Burden of Chikungunya and Dengue Transmission, Infection and Disease in Kenya
    Angelle Desiree LaBeaud; Fiscal Year: 2013
    ..cohorts in and near Msambweni (coastal) and Kisumu (western), Kenya, where there is year-round transmission of arboviruses, and is based on 10 years of collaborative longitudinal studies...
  23. West Nile Virus Infection: Novel Genetic Screens to Identify Important Host Genes
    Robert L Glaser; Fiscal Year: 2010
    ..The long term goal of this study is to understand how the molecular interactions that occur between arboviruses and their hosts determine infection susceptibility...
  24. Massively parallel sequencing of the diapause transcriptome in Aedes albopictus
    Christine Elsik; Fiscal Year: 2010
    ..dengue fever and also efficiently transmits yellow fever, chikungunya virus and several native North American arboviruses. The rapid spread of this mosquito from its native Asian range across the globe during the last 20 years and ..
  25. STRENGTHENING INFECTIOUS-DISEASE RESEARCH CAPACITY FOR PUBLIC-HEALTH ACTION IN
    Celia Cordon-Rosales; Fiscal Year: 2012
    ..Additionally, this effort offers the opportunity to detect novel arboviruses of public health significance...
  26. Marine Microbial Products as Novel Agents Against Neurotropic Arboviruses
    David J Miller; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Mosquito-borne viruses, or arboviruses, are among the most important emerging pathogens worldwide with a significant potential impact on human health, and are also prominent components of the NIAID ..
  27. A HTS Assay for Identifying Anti-Viral Drugs Against Arbovirus Infections
    Qianjun Li; Fiscal Year: 2007
    ..to transfer our HTS-ready, florescence based caspases-3/7 assay to identify novel anti-viral drugs against arboviruses infection based on the different host apoptotic responses in BTV infection model system...
  28. Ochlerotatus japonicus: Ecology of an Invasive Mosquito
    RICHARD FALCO; Fiscal Year: 2005
    ..Of special concern is the question of this species' vectorial capacity for local arboviruses; it is a competent vector of West Nile virus (WNV) in the lab and may serve as a bridge vector to humans in the ..
  29. Impact of climate change on mosquito-borne arbovirus transmission
    C M Barker; Fiscal Year: 2011
    ..the California Department of Public Health and local mosquito control agencies to mitigate West Nile and other arboviruses. Utilizing our extensive historical dataset, we anticipate modeling and evaluating retrospective trends and ..
  30. RNAi as a modulator of arbovirus vector competence in transgenic Aedes aegypti
    ALEXANDER WILLIAM EDUARD FRANZ; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Molecular interactions of medically important arthropod-borne viruses (arboviruses) with the mosquito, Aedes aegypti, are poorly described...
  31. Passerine filariasis and West Nile virus transmission
    JEFFERSON ARCHER VAUGHAN; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): In nature, vertebrate hosts of arboviruses often harbor parasites, including microfilariae...
  32. Defining the determinants on the alphavirus receptor NRAMP required for virus bin
    Sara Cherry; Fiscal Year: 2013
    ..Our central hypothesis is that dissecting the interactions of these medically important arboviruses with their receptor will reveal mechanisms that will aid in the development of antiviral treatments against ..
  33. Mechanisms of Enhanced Arbovirus Infection by Mosquito Saliva
    Kristen A Bernard; Fiscal Year: 2013
    ..Mosquito saliva potentiates viral replication for several different arboviruses, depending on the mosquito species, virus and experimental system;however, the mechanism(s) of enhanced viral ..
  34. RNA REPAIR AND RECOMBINATION--AN ALPHAVIRUS MODEL
    RAMASAMY RAJU; Fiscal Year: 2001
    ..b>Arboviruses, the largest group of animal RNA viruses, because of their wide tissue and host specificity, are forced to ..
  35. Invasive Aedes Mosquitoes and Dengue in Brazil
    Leon Philip Lounibos; Fiscal Year: 2010
    ..showed that effects of larval competition are also manifested in the competency of emerged adults to vector arboviruses in the laboratory, stressed Aedes females being more susceptible to infection with and dissemination of dengue ..
  36. Vaccines for Eastern and Western Equine Encephalitis Viruses
    Robert Whalen; Fiscal Year: 2007
    ..EEEV is in fact the most lethal of arboviruses. Clinical data of naturally acquired infection by WEEV suggest that the disease is less severe...
  37. Apoptosis as an anti-viral response in mosquito midgut
    ROLLIE CLEM; Fiscal Year: 2007
    ..provided by applicant): Mosquitoes are important vectors for a number of infectious diseases caused by arboviruses including West Nile virus, dengue virus, yellow fever virus, LaCrosse virus, and Venezuelan, eastern and ..
  38. Nucleotide Pools and the Replication of Sindbis Virus
    Victor Stollar; Fiscal Year: 2003
    Close to 400 arthropod-borne viruses (arboviruses) have been identified, many of which cause serious human disease...
  39. Mosquito Immunity to Alphaviruses
    Brian Foy; Fiscal Year: 2006
    ..As a fundamental process for transmission, these arboviruses must replicate in mosquito gut tissues, disseminate throughout the mosquito body, and eventually infect the ..
  40. HEALTH BURDERN OF COINFECTING DEER ASSOCIATED ZOONOSES
    Peter Krause; Fiscal Year: 2001
    ..we shall focus on the agents of Lyme disease, babesiosis, human granulocytic ehrlichiosis and TBE-group arboviruses, we shall seek to document the presence of other tick-borne microbes and the frequency of infection by such ..
  41. ECOLOGY AND CONTROL OF ARBOVIRUSES
    James Hardy; Fiscal Year: 1990
    ..be to expand knowledge and understanding of the interaction of ecological and environmental factors that allow arboviruses to be maintained in their basic transmission cycles and to be transmitted tangentially to human populations...
  42. VENUE OF AMPLIFICATION OF EEE OUTBREAKS
    Andrew Spielman; Fiscal Year: 2004
    ..of avian daily dispersal; (2) define the reservoir characteristics of starlings, grackles and robins for these arboviruses by comparing virus-competence, frequency of feeding contact by enzootic vector mosquitoes with these birds, and ..
  43. Arbovirus quasispecies-impact of arthropod transmission
    GREGORY EBEL; Fiscal Year: 2004
    DESCRIPTION (provided by the applicant): The introduction of exotic arboviruses into new ecological niches has occurred with increasing frequency in recent years, presenting an ongoing challenge to the public health and biodefense ..
  44. VECTOR ADAPTATION AND DENGUE EMERGENCE
    Scott Weaver; Fiscal Year: 2001
    Most arboviruses are maintained in wild animal populations and only occasionally infect people. However, dengue (DEN) virus is an important exception that relies only on a human vertebrate reservoir and Aedes aegypti or Ae...
  45. Tropical Vector-borne Viral and Rickettsial Infections
    David Walker; Fiscal Year: 2007
    ..africae, to identify African human ehrlichioses, and to determine the ecology of sylvatic dengue and other arboviruses and to identify and characterize emerging infections in general in west central Africa...
  46. TOGAVIRUS--VECTOR INTERACTIONS
    Thomas Scott; Fiscal Year: 1992
    ..This observation challenges previous beliefs regarding the benign nature of mosquito infection with arboviruses, and suggests potential mechanisms which may 1) facilitate rapid virus dissemination within the mosquito and ..
  47. MECHANISMS OF ARBOVIRUS ADAPTATION TO MOSQUITO VECTORS
    Scott Weaver; Fiscal Year: 2000
    Highly specific interactions regulate the transmission of many arboviruses by mosquito vectors, influencing their ability to cause disease outbreaks...
  48. WILDLIFE RESERVOIRS OF ARBOVIRUSES
    THOMAS YUILL; Fiscal Year: 1980
    ..3) The reassortants and their LAC and SSH virus parents will be tested in snowshoe hares, assuming that we have more success at finding susceptible individuals in the field than we have had in the past 18 months...
  49. Molecular Systematics of Culex (Melanoconian) spp.vecto*
    Scott Weaver; Fiscal Year: 2004
    Many important zoonotic arboviruses utilize mosquito vectors in the Culex (Melanoconion) subgenus, and one particular group (the Spissipes Section, 23 species) includes most of these vectors in the neotropics...
  50. Mosquito-Virus-Host Interactions and WNV Pathogenesis
    Kristen Bernard; Fiscal Year: 2007
    Arthropod-borne viruses (arboviruses) exist in a complex cycle between their arthropod vector and vertebrate host...
  51. DETECTING EMERGING VECTOR-BORNE ZOONOTIC PATHOGENS IN INDONESIA
    Khin Saw Aye Myint; Fiscal Year: 2013
    ..Indonesia is most likely an important place for the study of emerging zoonotic pathogens, especially arboviruses. Numerous arboviral outbreaks during the past decade have demonstrated that arthropod-borne pathogens continue ..
  52. MOLECULAR INVESTIGATION OF THE ECOLOGY OF EEE VIRUS
    PATRICIA REPIK; Fiscal Year: 1991
    ..This information may also serve as a model for defining the ecology of other important arboviruses.
  53. Biology-Pathology of Arbovirus Persistence in a Mosquito Host
    Doria Bowers; Fiscal Year: 2007
    ..for tissue-specific genetic variants will increase our knowledge of pathogen transmission and maintenance of arboviruses in nature...
  54. GENETICS OF TRANSOVARIOLE TRANSMISSION
    William Black; Fiscal Year: 1999
    Anthropod-borne viral diseases remain very significant causes of morbidity and mortality in humans. Many arboviruses in enzootic cycles through a phenomenon known as Transovarial Transmission (TOT)...
  55. Task D04:World Reference Center for Emerging Viruses and Arboviruses
    WILLIAM COALE; Fiscal Year: 2013
    ..This contract provides for the development and standardization of non-human primate models for infectious diseases, and may include efficacy testing of candidate products, including GLP studies to support licensure. ..
  56. Biosecurity Enhancements for the Rocky Mountain Regional Biocontainment Laborator
    Sue Vandewoude; Fiscal Year: 2009
    ..The IDRC supports research on select agents, emerging pathogens, arboviruses, and mycobacterial diseases at Animal Biosafety Levels 2 and 3, and as such, is a unique facility in the Rocky ..
  57. WORLD REFERENCE CENTER FOR ARBOVIRUSES
    Robert Tesh; Fiscal Year: 2002
    ..Reference Collection and to support other research and service activities of the World Reference Center for Arboviruses. These latter activities include: (1) virus identification and characterization; (2) investigation and ..
  58. ANTI-IDIOTYPE VACCINES AGAINST FLAVIVIRUSES
    Craig Wright; Fiscal Year: 1990
    ..murine monoclonal antiidiotype vaccine that will elicit neutralizing antibodies against the flavivirus group of arboviruses, in particular dengue types 1-4...
  59. WORLD REFERENCE CENTER FOR ARBOVIRUSES
    Robert Tesh; Fiscal Year: 2012
    ..The repository is responsible for collecting, maintaining, preparing and distributing arthropod-borne and other zoonotic viruses and associated reagents to the scientific community worldwide...
  60. ECOLOGY AND GENETICS OF VENEZUELAN EQUINE ENCEPHALITIS
    Scott Weaver; Fiscal Year: 2005
    ..This information will be invaluable in targeting prevention and control resources, especially for obtaining maximum benefit in developing countries with limited resources. ..