toxic plants

Summary

Summary: Plants or plant parts which are harmful to man or other animals.

Top Publications

  1. ncbi Plant exposures: wilderness medicine
    Sophia Dyer
    Department of Emergency Medicine, Boston Medical Center, One Boston Medical Center Place, Boston, MA 02118, USA
    Emerg Med Clin North Am 22:299-313, vii. 2004
  2. ncbi Poisoning due to white seed variety of Abrus precatorius
    V V Pillay
    Dept of Analytical Toxicology and Poison Control Centre, Amrita Institute of Medical Sciences and Research, Cochin 682026
    J Assoc Physicians India 53:317-9. 2005
  3. ncbi Accidental mydriasis from exposure to Angel's trumpet (Datura suaveolens)
    Ulf Havelius
    Department of Ophthalmology, Malmo University Hospital, University of Lund, Malmo, Sweden
    Acta Ophthalmol Scand 80:332-5. 2002
  4. ncbi Abrus precatorius, Gaertin--an ayurvedic potent phytomedicine
    A D B Vaidya
    J Assoc Physicians India 53:739-40; author reply 740. 2005
  5. ncbi [General situation of the toxicity researches on Senecio]
    Ai Hua Liang
    Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China
    Zhongguo Zhong Yao Za Zhi 31:93-7. 2006
  6. pmc Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema
    N Yamada
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Sendai 980 8574, Japan
    Am J Hum Genet 66:187-95. 2000
  7. ncbi Psychotropic substance-seeking: evolutionary pathology or adaptation?
    R J Sullivan
    Department of Anthropology, The University of Auckland, New Zealand
    Addiction 97:389-400. 2002
  8. ncbi Initial tobacco use episodes in children and adolescents: current knowledge, future directions
    T Eissenberg
    Department of Psychology and Pharmacology, and Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Box 980205, Richmond, VA 23298 0205, USA
    Drug Alcohol Depend 59:S41-60. 2000
  9. ncbi Localization of AtROP4 and AtROP6 and interaction with the guanine nucleotide dissociation inhibitor AtRhoGDI1 from Arabidopsis
    F Bischoff
    Max Delbruck Laboratorium in der Max Planck Gesellschaft, Köln Vogelsang, Germany
    Plant Mol Biol 42:515-30. 2000
  10. ncbi Betel quid and areca nut are carcinogenic without tobacco
    Dinesh C Sharma
    Lancet Oncol 4:587. 2003

Research Grants

Detail Information

Publications226 found, 100 shown here

  1. ncbi Plant exposures: wilderness medicine
    Sophia Dyer
    Department of Emergency Medicine, Boston Medical Center, One Boston Medical Center Place, Boston, MA 02118, USA
    Emerg Med Clin North Am 22:299-313, vii. 2004
    ..This article discusses poisonous plants, the symptoms that might arise if they are ingested, and the treatments that should be administered to patients...
  2. ncbi Poisoning due to white seed variety of Abrus precatorius
    V V Pillay
    Dept of Analytical Toxicology and Poison Control Centre, Amrita Institute of Medical Sciences and Research, Cochin 682026
    J Assoc Physicians India 53:317-9. 2005
    ..He recovered after a prolonged duration of hospital treatment without any subsequent complications or sequelae. The case is being reported on account of its rarity...
  3. ncbi Accidental mydriasis from exposure to Angel's trumpet (Datura suaveolens)
    Ulf Havelius
    Department of Ophthalmology, Malmo University Hospital, University of Lund, Malmo, Sweden
    Acta Ophthalmol Scand 80:332-5. 2002
    ..To report clinical findings after accidental instillation into the eye of sap from Angel's trumpet (Datura suaveolens)...
  4. ncbi Abrus precatorius, Gaertin--an ayurvedic potent phytomedicine
    A D B Vaidya
    J Assoc Physicians India 53:739-40; author reply 740. 2005
  5. ncbi [General situation of the toxicity researches on Senecio]
    Ai Hua Liang
    Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China
    Zhongguo Zhong Yao Za Zhi 31:93-7. 2006
    ..in China were also recapitulated. The proposals for the application and development of Senecio spp. were put forward...
  6. pmc Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema
    N Yamada
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Sendai 980 8574, Japan
    Am J Hum Genet 66:187-95. 2000
    ..These findings suggest that the large size of a (GT)n repeat in the HO-1 gene promoter may reduce HO-1 inducibility by reactive oxygen species in cigarette smoke, thereby resulting in the development of CPE...
  7. ncbi Psychotropic substance-seeking: evolutionary pathology or adaptation?
    R J Sullivan
    Department of Anthropology, The University of Auckland, New Zealand
    Addiction 97:389-400. 2002
    ....
  8. ncbi Initial tobacco use episodes in children and adolescents: current knowledge, future directions
    T Eissenberg
    Department of Psychology and Pharmacology, and Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Box 980205, Richmond, VA 23298 0205, USA
    Drug Alcohol Depend 59:S41-60. 2000
    ..Another goal is to outline a research agenda designed to learn more about initial tobacco use episodes and the effects of nicotine in children. An ethical rationale and some potential methods for this research agenda are presented...
  9. ncbi Localization of AtROP4 and AtROP6 and interaction with the guanine nucleotide dissociation inhibitor AtRhoGDI1 from Arabidopsis
    F Bischoff
    Max Delbruck Laboratorium in der Max Planck Gesellschaft, Köln Vogelsang, Germany
    Plant Mol Biol 42:515-30. 2000
    ..Recombinant GST-AtRhoGDI1 could bind GFP-AtROP4 from transgenic tobacco BY2 cell extracts, confirming the interaction observed with the two-hybrid system...
  10. ncbi Betel quid and areca nut are carcinogenic without tobacco
    Dinesh C Sharma
    Lancet Oncol 4:587. 2003
  11. ncbi Model of microtine cycles caused by lethal toxins in non-preferred food plants
    Adam Kent
    School of Biological Sciences, Biodiversity and Ecology Division, University of Southampton, Bassett Crescent East, Southampton SO16 7PX, UK
    J Theor Biol 234:593-604. 2005
    ..Fewer criteria could be met in variations on the model, in which the non-preferred food was equally as nutritious as the preferred food or was continuously toxic...
  12. ncbi Rapid HPLC screening of jasmonate-induced increases in tobacco alkaloids, phenolics, and diterpene glycosides in Nicotiana attenuata
    M Keinanen
    Department of Molecular Ecology, Max Planck Institute for Chemical Ecology, Carl Zeiss Promenade 10, D 07745 Jena, Germany
    J Agric Food Chem 49:3553-8. 2001
    ..5-, 1.4-, and 1.9-fold, respectively) but left others, such as rutin, unchanged. Such broad-based analytical screens will help characterize environmental and genetic changes in secondary metabolite profiles...
  13. ncbi Plant-herbivore interactions mediated by plant toxicity
    Zhilan Feng
    Department of Mathematics, Purdue University, West Lafayette, IN 47907, United States
    Theor Popul Biol 73:449-59. 2008
    ....
  14. pmc Molecular interactions between the specialist herbivore Manduca sexta (Lepidoptera, Sphingidae) and its natural host Nicotiana attenuata. IV. Insect-Induced ethylene reduces jasmonate-induced nicotine accumulation by regulating putrescine N-methyltransfer
    R A Winz
    Department of Molecular Ecology, Max Planck Institute for Chemical Ecology, Carl Zeiss Promenade 10, D-07745 Jena, Germany
    Plant Physiol 125:2189-202. 2001
    ..sexta herbivory. We conclude that attack from this nicotine-tolerant specialist insect causes N. attenuata to produce ethylene, which directly suppresses the nitrogen-intensive biosynthesis of nicotine...
  15. ncbi Evolution and addiction
    Randolph M Nesse
    The University of Michigan, Department of Psychiatry, Ann Arbor 48104, USA
    Addiction 97:470-1. 2002
  16. ncbi Role of reactive oxygen species in the development of cytotoxicity with various forms of chewing tobacco and pan masala
    Manashi Bagchi
    Creighton University School of Pharmacy and Allied Health Professions, Omaha, NE 68178, USA
    Toxicology 179:247-55. 2002
    ..The results, thus, document that the cytotoxic effects of the chewing tobaccos including pan masalas are mediated through the production of the reactive oxygen species...
  17. ncbi Ultrasonographic evaluation of urinary bladder in normal, fern fed and enzootic bovine haematuria-affected cattle
    M Hoque
    Division of Surgery, Indian Veterinary Research Institute, Izatnagar, U P, India
    J Vet Med A Physiol Pathol Clin Med 49:403-7. 2002
    ..Post-sonographic urinalysis, biopsy and necropsy of selected cases further confirmed the sonographic findings...
  18. ncbi Ethnobotanical survey of folk toxic plants in southern part of Jordan
    Saleh Al-Qura'n
    Department of Biology, Mu tah University, P O Box 26, Karak, Jordan
    Toxicon 46:119-29. 2005
    ....
  19. ncbi The distinct disease phenotypes of the common and yellow vein strains of Tomato golden mosaic virus are determined by nucleotide differences in the 3'-terminal region of the gene encoding the movement protein
    K Saunders
    Department of Virus Research, John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, UK
    J Gen Virol 82:45-51. 2001
    ....
  20. ncbi Plant poisonings in children in the Czech Republic, 1996-2001
    Petra Vichova
    Department of Pharmaceutical Botany and Ecology, Faculty of Pharmacy, Charles University in Prague, Czech Republic
    Hum Exp Toxicol 22:467-72. 2003
    ....
  21. ncbi Calcinosis--calcinogenic plants
    J R B Mello
    Department of Pharmacology, Federal University of Rio Grande do Sul, R Sarmento Leite, 500 202, RS CEP 90046 900, Porto Alegre, Brazil
    Toxicon 41:1-12. 2003
    ..The understanding of the mechanisms involved with calcinosis contributed enormously to the compression of vitamin D mechanism. Research methods were developed and improved but a lot is to be done in this fascinating subject...
  22. ncbi Oleander toxicosis in a donkey
    Phoebe A Smith
    University of California Davis Veterinary Medical Teaching Hospital, Davis, CA 95616, USA
    J Vet Intern Med 17:111-4. 2003
  23. ncbi Poisoning of mice by Baccharis coridifolia: an experimental model
    Mary Suzan Varaschin
    UNESP Universidade Estadual Paulista, Campus de Jaboticabal, 14884 900 Via Paulo D Castelanne, s n Jaboticabal, SP, Brazil
    Vet Hum Toxicol 45:42-4. 2003
    ..Mice reproduce most of the lesions observed in naturally poisoned cattle and the use of this specie as an experimental model is valid...
  24. ncbi Oral health status among the tobacco and betel nut chewers in the Kishore Ganj District of Bangladesh. A statistical study
    N Eswar
    Indian J Dent Res 13:167-71. 2002
    ..This habit is prevalent among both the men and women in that district. The oral manifestations of 780 people were studied in depth and the results noted...
  25. ncbi Toxicology. Fruit bats linked to mystery disease
    Richard Stone
    Science 296:241. 2002
  26. ncbi A young child with altered mental status
    Diana Dunnigan
    Department of Pediatrics, Phoenix Children s Hospital, AZ, USA
    Clin Pediatr (Phila) 41:43-5. 2002
  27. ncbi Complete nucleotide sequence and host range of South African cassava mosaic virus: further evidence for recombination amongst begomoviruses
    L C Berrie
    Department of Molecular and Cell Biology, University of the Witwatersrand, Private Bag 3, PO Wits 2050, Johannesburg, South Africa
    J Gen Virol 82:53-8. 2001
    ..This is the first description of successful infection of cassava with a geminivirus using Agrobacterium tumefaciens...
  28. ncbi Grayanotoxin poisoning in three goats
    B Puschner
    California Animal Health and Food Safety Laboratory, School of Veterinary Medicine, University of California, Davis 95616, USA
    J Am Vet Med Assoc 218:573-5, 527-8. 2001
    ..Rhododendron poisoning should be considered in animals with clinical evidence of gastrointestinal tract irritation, cardiac arrhythmias, and neurologic signs...
  29. ncbi Prevalence of oral lesions among a sample of Bangladeshi medical users aged 40 years and over living in Tower Hamlets, UK
    N Pearson
    Tower Hamlets Healthcare NHS Trust, Community/Salaried Dental Services, Dental Department, St Leonard's Primary Care Centre, Nuttall Street, London E1 5LZ, UK
    Int Dent J 51:30-4. 2001
    ..Sensitively tailored health promotion interventions, which aim to reduce tobacco use, should be developed for this population...
  30. ncbi Expression of a plant gene with sequence similarity to animal TGF-beta receptor interacting protein is regulated by brassinosteroids and required for normal plant development
    J Jiang
    Department of Horticultural Science, North Carolina State University, Raleigh, NC 27695 7609, USA
    Plant J 26:35-45. 2001
    ..This correlative evidence suggests that a WD-domain protein with reported dual functions in vertebrates and fungi might mediate some of the molecular mechanisms underlying the regulation of plant growth and development by BRs...
  31. ncbi Correlation of endophyte toxins (ergovaline and lolitrem B) with clinical disease: fescue foot and perennial ryegrass staggers
    J Tor-Agbidye
    National Center for Toxicological Research, Jefferson, Arkansas 72079, USA
    Vet Hum Toxicol 43:140-6. 2001
    ..Cold environmental temperatures are equally important to toxin concentrations in precipitating fescue foot disease...
  32. ncbi Interplant alkaloid variation and Senecio vernalis toxicity in cattle
    M T Skaanild
    Department of Pharmacology and Pathobiology, The Royal Veterinary and Agricultural University, Copenhagen, Denmark
    Vet Hum Toxicol 43:147-51. 2001
    ..Cattle subsequently fed fresh plant material up to 1 kg/d for 8 d also had no change in liver enzyme activities. Cattle did not show any clinical signs of poisoning, and no morphological liver changes were observed...
  33. ncbi Pteridium aquilinum (bracken fern) toxicity in cattle in the humid Chaco of Tarija, Bolivia
    E Marrero
    National Center for Animal and Plant Health, CENSA, La Habana, Cuba
    Vet Hum Toxicol 43:156-8. 2001
    ..Carcinomas were in the urinary bladders and esophagus of 100% and 50% of the cattle, respectively. Control of the intoxication could be difficult due to geographic characteristics of this Bolivian region...
  34. ncbi Intoxication of goats by Plumbago scandens in Northeastern Brazil
    R M Medeiros
    , , Brazil
    Vet Hum Toxicol 43:167-9. 2001
    ..Reproduction of the disease with clinical signs similar to those observed by the farmer in the spontaneously affected goats suggests that the clinical mortality was caused by ingestion of Plumbago scandens...
  35. ncbi The potential toxicity of Ilex myrtifolia in beef cattle
    M Pence
    Department of Large Animal Medicine, The University of Georgia, Tifton 31794, USA
    Vet Hum Toxicol 43:172-4. 2001
    ....
  36. ncbi The management of Elephant's Ear poisoning
    D Tagwireyi
    Department of Pharmacy, Medical School, University of Zimbabwe, Avondale, Harare
    Hum Exp Toxicol 20:189-92. 2001
    ..There is a need to educate health care workers on the clinical management of Elephant's Ear poisoning especially in developing countries where there are limited resources...
  37. ncbi Seasonal variation in cotyledoside concentration of Tylecodon wallichii (Harv.) Tölken subsp. wallichii sampled in a krimpsiekte-prevalent region
    C J Botha
    Department of Pharmacology and Toxicology, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
    Onderstepoort J Vet Res 68:1-9. 2001
    ..The highest cotyledoside concentrations were detected in the flowering stalk. Cotyledoside was not the only component of this type in the plant, as mass spectrometry revealed the presence of other, possibly related, compounds...
  38. doi Cardiac glycoside poisoning following suicidal ingestion of Cerbera manghas
    Yi Cheng Tsai
    Clin Toxicol (Phila) 46:340-1. 2008
  39. ncbi The clinical, biochemical, haematological and pathological effects of long-term administration of Ipomoea carnea to growing goats
    B Schumaher-Henrique
    Department of Pathology, School of Veterinary Medicine, University of Sao Paulo, Av Prof Orlando Marques de Paiva 87, Sao Paulo SP, Brazil 05508 900
    Vet Res Commun 27:311-9. 2003
    ..All these alterations occurred in a dose-dependent manner...
  40. ncbi Grazing of spotted locoweed (Astragalus lentiginosus) by cattle and horses in Arizona
    J A Pfister
    ARS, USDA Poisonous Plant Research Laboratory, Logan, UT 84341, USA
    J Anim Sci 81:2285-93. 2003
    ..Although limited in scope, this study indicates that horses should not be exposed to spotted locoweed...
  41. ncbi Neurohistologic and ultrastructural lesions in cattle experimentally intoxicated with the plant Prosopis juliflora
    I M Tabosa
    Veterinary Faculty, Federal University of Campina Grande, Campus de Patos, Patos 58700 000, Paraiba, Brazil
    Vet Pathol 43:695-701. 2006
    ..Cranial nerve degeneration and denervation atrophy of the muscles occurs as a consequence of the neuronal lesion...
  42. ncbi Cleistanthus collinus poisoning
    S P E Benjamin
    Departments of Medicine and Nephrology, CSI Kalyani Multispeciality Hospital, Mylapore, Chennai
    J Assoc Physicians India 54:742-4. 2006
    ..We report ARDS, distal renal tubular acidosis and distributive shock secondary to inappropriate vasodilatation in a case following ingestion of its leaves...
  43. ncbi Intoxication with buckthorn (Karwinskia humboldtiana): report of three siblings
    L Valeria Ocampo-Roosens
    Departamento de Patologia, Hospital del Niño Morelense, Morelos, Mexico
    Pediatr Dev Pathol 10:66-8. 2007
    ..The clinical diagnosis of intoxicated patients can be difficult without a history of the fruit ingestion. We present a report of three siblings with buckthorn intoxication...
  44. ncbi A review of the hepatotoxic plant Lantana camara
    Om P Sharma
    Biochemistry Laboratory, Indian Veterinary Research Institute, Regional Station Kangra Valley, Palampur, India
    Crit Rev Toxicol 37:313-52. 2007
    ..Research is being conducted on new drug discovery based on natural products in different parts of the lantana plant...
  45. ncbi Microscopic morphology of Dichapetalum cymosum (Hook.) Engl. as an aid in the identification of leaf fragments from the digestive tract of poisoned animals
    D Van der Merwe
    Department of Diagnostic Medicine Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA
    J S Afr Vet Assoc 77:197-201. 2006
    ..cymosum and other species from the same habitat with macroscopic features that resemble those of D. cymosum, including Euclea crispa, Combretum zeyheri, Burkea afrikana and Lannea discolor...
  46. ncbi [Datura stramonium poisoning--a new problem in children and young people's toxicomania in Poland]
    Onufry Torbus
    I Katedry Pediatrii i Kliniki Gastroenterologii, Alergologii i Zaburzeń Rozwoju Wieku Dzieciecego, Slaskiej Akademii Medycznej w Katowicach
    Wiad Lek 55:950-7. 2002
    ..8 children required hydration in the second day of hospitalisation and 2 in the next 2 days. One child was treated in the Intensive Care Unit. The average hospitalisation period was 3.8 days...
  47. ncbi Food poisoning due to Jimson weed mimicking Bacillus cereus food intoxication in Austria, 2006
    R Fretz
    Int J Infect Dis 11:557-8. 2007
  48. ncbi Not your everyday anisocoria: angel's trumpet ocular toxicity
    Daniel Firestone
    Department of Emergency Medicine, University of California San Diego School of Medicine, San Diego, California, USA
    J Emerg Med 33:21-4. 2007
    ..The patient and his family were spared expensive and time-consuming tests (e.g., magnetic resonance imaging) or further referral. His symptoms resolved spontaneously in 3 days...
  49. ncbi Pharmacokinetics of 1,8-cineole, a dietary toxin, in the brushtail possum (Trichosurus vulpecula): significance for feeding
    S McLean
    School of Pharmacy, University of Tasmania, Hobart, Tasmania, Australia
    Xenobiotica 37:903-22. 2007
    ....
  50. ncbi Toxic hepatopathy in sheep associated with the ingestion of the legume Tephrosia cinerea
    Julio César A Santos
    Hospital Veterinario, CSTR, Universidade Federal de Campina Grande, Campus de Patos, Patos, Paraiba, 58700 000, Brazil
    J Vet Diagn Invest 19:690-4. 2007
    ..Seeds and leaves of the plant were examined by gas chromatography-mass spectrometry for the presence of pyrrolizidine alkaloids with negative results. It is concluded that the disease is caused by the ingestion of T. cinerea...
  51. ncbi Unilateral mydriasis due to Angel's trumpet
    Barbara Andreola
    Department of Pediatrics, University of Padova, Padova, Italy
    Clin Toxicol (Phila) 46:329-31. 2008
    ..There are many causes of bilateral and unilateral mydriasis. Common garden plants, such as Brugmansia (Angel's trumpet), contain tropane alkaloids...
  52. ncbi A potential krimpsiekte vaccine
    C J Botha
    Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110 South Africa
    Onderstepoort J Vet Res 74:307-14. 2007
    ..The immunized ewes (n = 2) remained clinically unaffected and the challenge was suspended following six daily injections. Vaccination as a means of preventing krimpsiekte seems to be quite feasible and deserves further investigation...
  53. ncbi Brunfelsia spp (yesterday, today, tomorrow) toxicity in four dogs
    M Singh
    Small Animal Specialist Hospital, North Ryde, NSW, 1670, Australia
    Aust Vet J 86:214-8. 2008
    ..Examination of faeces was required for diagnosis in all cases. Owners should also be questioned thoroughly about their dogs' access to such plants...
  54. ncbi Veratrum poisoning
    Leo J Schep
    National Poisons Centre, University of Otago, Dunedin, New Zealand
    Toxicol Rev 25:73-8. 2006
    ..The onset of symptoms occurs between 30 minutes and 4 hours, and the duration of the illness can range from 1 to 10 days; however, with prompt supportive care, patients typically make a full recovery within 24 hours...
  55. ncbi A comparative study of the mutagenicity of various types of tobacco products
    W S Rickert
    Labstat International ULC, 262 Manitou Drive, Kitchener, Ont, Canada N2C 1L3
    Regul Toxicol Pharmacol 48:320-30. 2007
    ..Corresponding values for TA100+S9 were cigars, 189%; cigarillos, 155%; pipe tobacco, 130%; bidis, 114% and ST, 34%. ST TA100+S9 response ranged from a low of 501 to a high of 8547 revertants/mg nicotine, depending on ST composition...
  56. pmc Medicinal uses of tobacco in history
    Anne Charlton
    School of Epidemiology and Health Sciences, Stopford Building, University of Manchester, Manchester M13 9PT, UK
    J R Soc Med 97:292-6. 2004
  57. ncbi Conditioning cattle to graze broom snakeweed (Gutierrezia sarothrae)
    M H Ralphs
    ARS, USDA Poisonous Plant Research Laboratory, and Animal, Dairy, and Veterinary Science Department, Utah State University, Logan 84341, USA
    J Anim Sci 82:3100-6. 2004
    ..In the small pastures of both the spring and fall grazing trials, 36 to 59% of snakeweed plants were grazed. Cattle can be forced to graze snake-weed in a short-duration, high-intensity grazing strategy...
  58. ncbi Prunus spp. intoxication in ruminants: a case in a goat and diagnosis by identification of leaf fragments in rumen contents
    Zaher A Radi
    Tifton Diagnostic and Investigational Laboratory, College of Veterinary Medicine, The University of Georgia, Tifton, GA 31793 1389, USA
    J Vet Diagn Invest 16:593-9. 2004
    ..in eastern North America: black cherry, Carolina laurel cherry, peach, English laurel cherry, choke cherry, and fire cherry...
  59. ncbi Juniper tar poisoning
    Suda Tekin Koruk
    Department of Infectious Diseases and Clinical Microbiology, Ankara Training and Education Hospital, Ankara, Turkey
    Clin Toxicol (Phila) 43:47-9. 2005
    ..After supportive and symptomatic treatment, the patient improved and was discharged in a good condition on the eleventh day...
  60. ncbi [Psychiatric aspects of plant poisonings]
    W Kawohl
    Psychiatrische Universitätsklinik Zürich, Schweiz
    Nervenarzt 76:875-6, 877-8. 2005
    ..This problem is discussed here, and advice for the prevention of plant poisonings and generally dealing with patients intoxicated by herbal poisons is given...
  61. ncbi [Case of accidental ingestion of caster beans: acute intoxication by ricin]
    Takashi Nishiyama
    Chudoku Kenkyu 18:149-50. 2005
  62. ncbi [Poisonous and less poisonous plants. Forsythia suspensa]
    Harald Haupt
    Kinderkrankenschwester 22:319. 2003
  63. ncbi [Poisonous and less poisonous plants]
    Harald Haupt
    Kinderkrankenschwester 23:23-4. 2004
  64. ncbi [Cardiotoxic plants]
    Beata Szkolnicka
    Katedra Toksykologii Klinicznej i Srodowiskowej, Collegium Medicum Uniwersytetu Jagiellońskiego, Krakowie
    Przegl Lek 62:621-3. 2005
    ..Species of cardiotoxic plants which may cause a danger in Poland are presented in the research. The toxic mechanisms of cardiac glycosides are specified...
  65. pmc Biomarkers for ragwort poisoning in horses: identification of protein targets
    Rowan E Moore
    Proteomics and Functional Genomics Research Group, Faculty of Veterinary Science, University of Liverpool, Crown Street, Liverpool, L69 7ZJ, UK
    BMC Vet Res 4:30. 2008
    ..In this study a non-invasive in vitro model system has been developed to investigate whether pyrrole toxins induce specific modifications of equine blood proteins that are detectable by proteomic methods...
  66. pmc Ammonia-regulated expression of a soybean gene encoding cytosolic glutamine synthetase in transgenic Lotus corniculatus
    G H Miao
    Department of Molecular Genetics and Biotechnology Center, Ohio State University, Columbus 43210
    Plant Cell 3:11-22. 1991
    ..corniculatus nodules, where a flux of ammonia is encountered by this tissue. The lack of expression of GS-GUS in the outer cortex of the nodules suggests that ammonia may not be able to diffuse outside the endodermis...
  67. ncbi O6-methylguanine-DNA methyltransferase activity in human buccal mucosal tissue and cell cultures. Complex mixtures related to habitual use of tobacco and betel quid inhibit the activity in vitro
    Y Liu
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Carcinogenesis 18:1889-95. 1997
    ..Finally, in vitro experiments suggested the potential inhibition of buccal mucosal MGMT activity by complex mixtures present in the saliva of tobacco and betel nut chewers...
  68. ncbi Differential extraction and protein sequencing reveals major differences in patterns of primary cell wall proteins from plants
    D Robertson
    Department of Biological Sciences, Durham University, South Road, Durham DH1 3LE, United Kingdom
    J Biol Chem 272:15841-8. 1997
    ..It appears that aspects of speciation reside in the complement of extracellular wall proteins. The data represent a protein resource for cell wall studies complementary to EST (expressed sequence tag) and DNA sequencing strategies...
  69. ncbi Sequence and functional analysis of the left-hand part of the T-region from the nopaline-type Ti plasmid, pTiC58
    L Otten
    Institute for Plant Molecular Biology of the CNRS, Strasbourg, France
    Plant Mol Biol 41:765-76. 1999
    ..Shoot formation could be restored by genes c and c' in co-infection experiments. Contrary to an earlier report, a C58 e gene deletion mutant was fully virulent on all plants tested...
  70. ncbi Molecular characterization of a subgroup I geminivirus from a legume in South Africa
    L Liu
    Department of Virus Research, John Innes Centre, Norwich, UK
    J Gen Virol 78:2113-7. 1997
    ....
  71. ncbi Ethnopharmacological survey of plants used in the traditional treatment of hypertension and diabetes in south-eastern Morocco (Errachidia province)
    A Tahraoui
    UFR Physiology Pharmacology, Laboratory of Animal Physiology, Department of Biology, Faculty of Sciences, Dhar El Mehraz, USMBA, BP 1976 Atlas Fez, Morocco
    J Ethnopharmacol 110:105-17. 2007
    ..The local people recognize the toxic plants and are very careful in using such plants, which are Citrullus colocynthis, Datura stramonium, Nerium oleander, ..
  72. ncbi [Intoxications with plants]
    Jacqueline Kupper
    Schweizerisches Toxikologisches Informationszentrum, Zurich
    Ther Umsch 66:343-8. 2009
    Ingestions of plants rarely lead to life-threatening intoxications. Highly toxic plants, which can cause death, are monkshood (Aconitum sp.), yew (Taxus sp.) and autumn crocus (Colchicum autumnale)...
  73. ncbi Sequestration of furostanol saponins by Monophadnus sawfly larvae
    Jose M Prieto
    Dipartimento di Chimica Bioorganica e Biofarmacia, Universita di Pisa, Via Bonanno 33, 56126 Pisa, Italy
    J Chem Ecol 33:513-24. 2007
    Sawfly larvae of the tribe Phymatocerini (Hymenoptera: Tenthredinidae), which are specialized on toxic plants in the orders Liliales and Ranunculales, exude a droplet of deterrent hemolymph upon attack by a predator...
  74. ncbi Poisoning in ostriches following ingestion of toxic plants--field observations
    Ross G Cooper
    Department of Physiology, College of Health Sciences, University of Zimbabwe, Mount Pleasant, Harare, Zimbabwe, Africa
    Trop Anim Health Prod 39:439-42. 2007
    ..from post-mortem and field studies were obtained that discussed poisoning in ostriches following ingestion of toxic plants. From the notes, all plants studied caused death in ostriches and there was systemic organ damage...
  75. ncbi Aconitum and Delphinium alkaloids of curare-like activity. QSAR analysis and molecular docking of alkaloids into AChBP
    M A Turabekova
    Interdisciplinary Center for Nanotoxicity, Jackson State University, 1400 J R Lynch Street, P O Box 17910, Jackson, MS 39217, USA
    Eur J Med Chem 45:3885-94. 2010
    Early studies have shown that some of diterpenoid alkaloids, found in highly toxic plants of the genera Aconitum and Delphinium, act at neuronal nicotinic acetylcholine receptors (nAChRs) and exhibit potent N-cholinolytic activity...
  76. ncbi [Spastic paraparesis due to long term consumption of wild cassava (Manihot esculenta): a neurotoxic model of motor neuron disease]
    F J Carod-Artal
    Servicio de Neurologia, Hospital Sarah, Brasilia DF, Brasil
    Rev Neurol 29:610-3. 1999
    ....
  77. ncbi The 'human revolution' in lowland tropical Southeast Asia: the antiquity and behavior of anatomically modern humans at Niah Cave (Sarawak, Borneo)
    Graeme Barker
    McDonald Institute for Archaeological Research, University of Cambridge, Downing Street, Cambridge CB2 3ER, UK
    J Hum Evol 52:243-61. 2007
    ..during these times was marked by habitat-tailored hunting technologies, the collection and processing of toxic plants for consumption, and, perhaps, the use of fire at some forest-edges...
  78. ncbi Ethnopharmacological survey of medicinal herbs in Jordan, the Ajloun Heights region
    Talal Aburjai
    Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Amman 11942, Jordan
    J Ethnopharmacol 110:294-304. 2007
    ..The use of moderately unsafe or toxic plants was noted to be practiced by practitioners and herbalists rather than the locals...
  79. ncbi Ethnopharmacological survey of medicinal plants used for the treatment of diabetes mellitus, hypertension and cardiac diseases in the south-east region of Morocco (Tafilalet)
    M Eddouks
    UFR Physiology of the Nutrition and Endocrinian Pharmacology, Faculty of Sciences and Techniques Errachidia, B P 509, Boutalamine, Errachidia, Morocco
    J Ethnopharmacol 82:97-103. 2002
    ..Many parameters have been evaluated such as knowledge of the toxic plants, doses, parts used, etc...
  80. ncbi Pyrrolizidine alkaloid-containing toxic plants (Senecio, Crotalaria, Cynoglossum, Amsinckia, Heliotropium, and Echium spp.)
    Bryan L Stegelmeier
    USDA Agricultural Research Service, Poisonous Plant Research Laboratory, 1150 East, 1400 North, Logan, UT 84341, USA
    Vet Clin North Am Food Anim Pract 27:419-28, ix. 2011
    ..Current diagnostic techniques, treatments, and strategies to avoid losses to PA poisoning are also reviewed...
  81. ncbi Detection of aristolochic acid I, tetrandrine and fangchinoline in medicinal plants by high performance liquid chromatography and liquid chromatography/mass spectrometry
    H L Koh
    Department of Pharmacy, Faculty of Science, National University of Singapore 18 Science Drive 4, Singapore 117543, Singapore
    J Pharm Biomed Anal 40:653-61. 2006
    Problems with identification and labeling of medicinal plants, as well as substitution/adulteration of non-toxic plants by toxic ones have previously led to cancer, renal failure and even deaths...
  82. ncbi Genus identification of toxic plant by real-time PCR
    Shuji Matsuyama
    Forensic Science Laboratory, Shiga Police Headquarters, 1 34 3 Karasaki, Otsu, Shiga, 520 0106, Japan
    Int J Legal Med 125:211-7. 2011
    Some plants have toxicities that are dangerous for humans. In the case of poisoning by toxic plants, a rapid and easy screening test is required for accurate medical treatment or forensic investigation...
  83. ncbi Larkspur (Delphinium spp.) poisoning in livestock
    J A Pfister
    Poisonous Plant Research Laboratory, ARS, USDA, Logan, UT 84341, USA
    J Nat Toxins 8:81-94. 1999
    Larkspurs (Delphinium spp.) are toxic plants that contain numerous diterpenoid alkaloids which occur as one of two structural types: (1) lycotonine, and (2) 7,8-methylenedioxylycoctonine (MDL-type)...
  84. ncbi Integration of herbal medicine into modern medical practices: issues and prospects
    Harry H S Fong
    UIC NIH Center for Botanical Dietary Supplements Research, College of Pharmacy, University of Illinois at Chicago, 60612, USA
    Integr Cancer Ther 1:287-93; discussion 293. 2002
    ..toxins, environmental pollutants, or heavy metals; or finished products that are adulterated with foreign toxic plants or synthetic pharmaceutical agents can lead to adverse events...
  85. ncbi Development of enzyme-linked immunosorbent assays for the hepatotoxic alkaloids riddelliine and riddelliine N-oxide
    S T Lee
    Poisonous Plant Research Laboratory, Agricultural Research Service, U S Department of Agriculture, 1150 East 1400 North, Logan, Utah 84341, USA
    J Agric Food Chem 49:4144-51. 2001
    ..These findings suggest that these techniques will be excellent tools to diagnose poisoned animals and identify highly toxic plants.
  86. ncbi Knowledge discovery in traditional Chinese medicine: state of the art and perspectives
    Yi Feng
    AdvanCed Computing aNd sysTem CCNT Lab, College of Computer Science, Zhejiang University, Hangzhou 310027, PR China
    Artif Intell Med 38:219-36. 2006
    ..This paper aims at providing an overview of recent KDD studies in TCM field...
  87. ncbi An extended outbreak of congenital chondrodysplasia in calves in South East Australia
    J G Cave
    Department of Primary Industries, 1 McKoy St, Wodonga, Vic 3690
    Aust Vet J 86:130-5. 2008
    ..To report an outbreak of congenital chondrodystrophy in calves in South East Australia...
  88. ncbi Guam ALS/parkinsonism-dementia: a long-latency neurotoxic disorder caused by "slow toxin(s)" in food?
    P S Spencer
    Department of Neuroscience, Albert Einstein College of Medicine, Bronx, N Y 10461
    Can J Neurol Sci 14:347-57. 1987
    ..Evidence is presented in support of the proposal that heavy use of certain toxic plants, notably cycads, a traditional source of food and medicine for the Chamorro people, plays an important ..
  89. ncbi Pyrrolizidine alkaloid poisoning of yaks (Bos grunniens) and confirmation by recovery of pyrrolic metabolites from formalin-fixed liver tissue
    H Winter
    University of Queensland, Department of Veterinary Pathology, Brisbane, Australia
    Res Vet Sci 52:187-94. 1992
    ..Pyrrolizidine alkaloid poisoning seriously affects the livelihood of the local population which depends almost entirely on the yak. Various control measures are discussed. The key to be found is the identification of the toxic plants.
  90. ncbi Integrating the costs of plant toxins and predation risk in foraging decisions of a mammalian herbivore
    Sahar N Kirmani
    School of Biological Sciences, The University of Sydney, Sydney, NSW, Australia
    Oecologia 164:349-56. 2010
    Foraging herbivores must satisfy their nutrient requirements in a world of toxic plants while also avoiding predators...
  91. ncbi Effects of consumption of juniper (Juniperus monosperma) on cost of thermoregulation in the woodrats Neotoma albigula and Neotoma stephensi at different acclimation temperatures
    James D McLister
    Biology Department, 257 South 1400 East, Room 201, University of Utah, Salt Lake City, Utah 84103, USA
    Physiol Biochem Zool 77:305-12. 2004
    A study was done to test whether toxic plants that occur naturally in the diet affect thermoregulation in mammalian herbivores...
  92. ncbi Can Batesian mimicry help plants to deter herbivores?
    Giovanna Massei
    Central Science Laboratory, Sand Hutton, York YO41 1LZ, UK
    Pest Manag Sci 63:559-63. 2007
    Several authors have suggested that edible plants could avoid herbivory by mimicking olfactory cues of toxic plants. However, very few studies have been carried out to test this hypothesis...
  93. ncbi Identification of poisonous plants by DNA barcoding approach
    Ilaria Bruni
    ZooPlantLab, Dipartimento di Biotecnologie e Bioscienze, Universita degli Studi di Milano Bicocca, Piazza della Scienza 2, 20126, Milan, Italy
    Int J Legal Med 124:595-603. 2010
    ..The objective of this research is to test DNA barcoding approach as a new universal tool to identify toxic plants univocally and rapidly...
  94. ncbi Ensuring the safety of botanical dietary supplements
    Richard B van Breemen
    University of Illinois at Chicago National Institutes of Health Center for Botanical Dietary Supplements Research, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, L 60612, USA
    Am J Clin Nutr 87:509S-13S. 2008
    ..examples of acute toxicity caused by botanical dietary supplements have been caused by the substitution of toxic plants for the desired species, probably through misidentification or production errors, or by contamination with ..
  95. ncbi Comparative analysis of microbial diversity in Longitarsus flea beetles (Coleoptera: Chrysomelidae)
    Scott T Kelley
    Department of Biology, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182, USA
    Genetica 139:541-50. 2011
    ..This genus of beetle herbivores contains host plant specialists and generalists that feed on a diverse array of toxic plants. Using a deep-sequencing approach, we characterized the MCD of eleven Longitarsus species across the genus, ..
  96. ncbi Identifying plant poisoning in livestock: diagnostic approaches and laboratory tests
    Bryan L Stegelmeier
    USDA Agricultural Research Service, Poisonous Plant Research Laboratory, 1150 East 1400 North, Logan, UT 84341, USA
    Vet Clin North Am Food Anim Pract 27:407-17, ix. 2011
    Plant poisoning is often associated with a variety of livestock diseases and unexplained animal deaths. Although toxic plants commonly poison livestock and it is estimated to cost the livestock industry in the western United States more ..
  97. ncbi Evidence for trans-generational medication in nature
    Thierry Lefevre
    Biology Department, Emory University, 1510 Clifton Road, Atlanta, GA 30322, USA
    Ecol Lett 13:1485-93. 2010
    ..Instead, adult butterflies preferentially laid their eggs on toxic plants that reduced parasite growth and disease in their offspring caterpillars...
  98. ncbi Ethnoveterinary medicine in the Arribes del Duero, western Spain
    Jose A Gonzalez
    Departamento de Botanica, Universidad de Salamanca, E 37071, Salamanca, Spain
    Vet Res Commun 35:283-310. 2011
    ..We also identify several plants used as bedding or fodder for livestock and discuss the relevance of some toxic plants and some "magical-curative" aspects reported in the territory.
  99. ncbi Plant poisoning
    Blake Froberg
    Indiana Poison Center, Methodist Hospital, Clarian Health Partners, Indiana University School of Medicine, Indianapolis, IN 46206 1367, USA
    Emerg Med Clin North Am 25:375-433; abstract ix. 2007
    Each year over 100,000 exposures to toxic plants are reported to poison centers throughout the United States...
  100. ncbi Multifaceted determinants of host specificity in an aphid parasitoid
    Nicolas Desneux
    Department of Entomology, University of Minnesota, 1980 Folwell Avenue, Saint Paul, MN 55108, USA
    Oecologia 160:387-98. 2009
    ..experiments: the presence of endosymbiotic bacteria conferring resistance to parasitoids, and aphids feeding on toxic plants. An association between resistance and endosymbiont infection was found in one species (Aphis craccivora), and ..
  101. ncbi [Screening of harmine tolerance/degrading bacteria from camel rumen]
    Dengdi An
    College of Life Science, Xinjiang Normal University, Urumqi 830054, China
    Wei Sheng Wu Xue Bao 50:1001-7. 2010
    ..Camels mainly live in desert or semi-desert areas, with the robust gastrointestine system in digesting various feed including toxic plants without disease symptoms.

Research Grants63

  1. Genetic Mapping Of Novel Molecular Players in Itch
    RACHEL BETH BREM; Fiscal Year: 2013
    ..serves an important protective function by warning against harmful agents in the environment such as insects, toxic plants or other irritants...
  2. Molecular Determinants for the Bioactivity of the Flavonoid Quercetin
    Temesgen Samuel; Fiscal Year: 2010
    ..Moreover, Quercetin has been described as one of the principal molecules of some toxic plants. Therefore, the conditions under which Quercetin is bioactive as an anti-tumor agent or as a carcinogen are not ..
  3. Decision Support System for Youth Well Being
    Herbert Severson; Fiscal Year: 2006
    ..abstract_text> ..
  4. Interactive Tobacco Cessation for College Students
    Herbert Severson; Fiscal Year: 2004
    ..abstract_text> ..
  5. Tobacco World: Interactive Tobacco Education for Teens
    Herbert Severson; Fiscal Year: 2007
    ..A companion website will offer administrative and scoring feedback to teachers via the Internet. [unreadable] [unreadable] [unreadable]..
  6. QuitSpit: An Internet-Based Smokeless Tobacco Cessation Program for Teens
    Herbert H Severson; Fiscal Year: 2010
    ....
  7. EVALUATION OF SELF HELP SMOKEELESS TOBACCO CESSATION
    Herbert Severson; Fiscal Year: 2001
    ..Data from this study can significantly contribute to our understanding of how to provide effective, low-intensity programs to help adults quit their use of snuff or chewing tobacco. ..
  8. Interactive Internet Intervention for Positive Parenting
    Herbert Severson; Fiscal Year: 2005
    ..The proposed design will provide important practical information about the feasibility and effectiveness of an Internet parenting intervention in effecting both parenting behavior and child behavior over a three year period. ..
  9. SpitWorld: Interactive Tobacco Education for Adolescents
    Herbert Severson; Fiscal Year: 2005
    ..The program will be evaluated by pre and post assessment, and followup assessments at 6 months to evaluate the impact of the program on intentions, risk perception, and tobacco use. ..
  10. A Dental Education Program in Tobacco
    Herbert Severson; Fiscal Year: 2003
    ..abstract_text> ..
  11. Chemoprevention in Mice after Tobacco Smoke Exposure
    Hanspeter Witschi; Fiscal Year: 2004
    ..Eventually, these preclinical studies in an animal model of "former smokers" will help to evaluate the potential usefulness and also possible dosage regimens of chemopreventive agents characterized by their suppressing action. ..
  12. MECHANISMS OF CHLORPYRIFOS DEVELOPMENTAL NEUROTOXICITY
    Theodore Slotkin; Fiscal Year: 2004
    ..Molecular mechanisms of developmental neurotoxicity can be determined and linked to eventual alterations in behavioral performance. ..
  13. Fetal & Adolescent Nicotine Effects on CNS 5HT Systems
    Theodore Slotkin; Fiscal Year: 2003
    ..abstract_text> ..
  14. DRUGS AND DEVELOPMENT OF THE ADRENERGIC NERVOUS SYSTEM
    Theodore Slotkin; Fiscal Year: 2003
    ....
  15. Rural Elders' Diabetes Self Management: Development of a Common Sense Model Inven
    Sara A Quandt; Fiscal Year: 2010
    ....
  16. Smoking Versus Alternative Reinforcers in Adolescents
    Suzanne Colby; Fiscal Year: 2007
    ..Study findings will advance our understanding of reinforcement mechanisms underlying adolescent smoking, which could also have implications for understanding and treating adolescent drug use more generally. ..
  17. Mechanisms of prostate cancer prevention by lycopene
    Richard van Breemen; Fiscal Year: 2007
    ..These human studies will provide vital information for the design of future clinical trials investigating the chemoprevention of prostate cancer by lycopene. [unreadable] [unreadable] [unreadable]..
  18. Randomized Trial of a State Tobacco Prevention Program
    Anthony Biglan; Fiscal Year: 2009
    ..abstract_text> ..
  19. Micellar VIP Nanoparticles for Rheumatoid Arthritis
    Israel Rubinstein; Fiscal Year: 2007
    ..abstract_text> ..
  20. Mechanisms of HSF1-mediated Repression of TNF-alpha
    Jeffrey Hasday; Fiscal Year: 2007
    ..The proposed studies will provide new insight into how the biochemical events that regulate host defenses is modified by the temperature increase that occurs during fever. ..
  21. HPLC time-of-flight mass spectrometer for accurate mass measurements
    Richard van Breemen; Fiscal Year: 2007
    ..to natural product chemists and synthetic organic chemists in the user community who rely upon rapid analyses of their compounds in order to advance with their NIH-funded research programs [unreadable] [unreadable] [unreadable]..
  22. Brief Alcohol Intervention for School-to-Work Transitions
    Suzanne M Colby; Fiscal Year: 2010
    ..The proposed research would test the effects of BMI specifically in the under-studied and under-treated population of heavy drinking non-college young adults. ..
  23. Diet, Genetic Susceptibility and Colorectal Neoplasia
    Loic Le Marchand; Fiscal Year: 2006
    ..Genotyping for random markers will permit to exclude residual confounding by ethnicity. ..
  24. Clinical models for evaluating PREPs for tobacco users
    Thomas Eissenberg; Fiscal Year: 2008
    ..This proposal's clinical model will likely be an important component of a comprehensive approach to predict if PREPs for tobacco users increase, decrease, or fail to change tobacco's health risks. ..
  25. ABCA1 agonist peptides for therapeutic use
    JOHN BIELICKI; Fiscal Year: 2008
    ..The research is likely to have a high impact on public health, since the therapeutics will be amenable to the widespread treatment of atherosclerosis. [unreadable] [unreadable] [unreadable] [unreadable]..
  26. TEEN TOBACCO USE IN A BIRTH COHORT & PRENATAL EFFECTS
    MARIE CORNELIUS; Fiscal Year: 2009
    ..Also, with further physical and CNS maturation in adolescence, we can assess whether effects of PTE on growth, cognitive, neuropsychological, and behavioral outcomes are maintained and whether new deficits occur with maturation. ..
  27. JUSTA: Justice and Health for Poultry Workers
    SARA QUANDT; Fiscal Year: 2008
    ..abstract_text> ..
  28. Hawaii Colorectal Cancer Family Registry
    Loic Le Marchand; Fiscal Year: 2008
    ..We will also propose a CFR pilot study exploring the feasibility of assessing assorted mating as evidence for population stratification. ..
  29. Ethnic/Racial Minorities in the Colon CFR
    Loic Le Marchand; Fiscal Year: 2008
    ..abstract_text> ..
  30. Case-Control Study of Adenoma in Sao Paulo Japanese
    Loic Le Marchand; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  31. Genetic Predictors for DNA Repair Phenotype in CMM
    Qingyi Wei; Fiscal Year: 2008
    ..When the combined NER genotype representing genetic susceptibility to CMM is identified and is confirmed in the general population, it may have a significant impact on primary prevention of CMM. ..
  32. Neurodegenration and Mitochnodrial Dysfunction in Aging
    Stephen Bondy; Fiscal Year: 2008
    ..This is also likely to be relevant to slowing the onset of, and reducing the incidence of, several neurodegenerative diseases where age is a major co-factor. [unreadable] [unreadable]..
  33. The contribution of heat shock/stress pathways to acute lung injury
    Jeffrey D Hasday; Fiscal Year: 2010
    ..Ablating fever may eliminate its beneficial as well as its harmful effects. We expect that a better understanding of its molecular mechanisms will allow us to selectively block the harmful effects of fever/hyperthermia. ..
  34. Smokers' Quitline for Asian Language Speakers
    Shu Hong Zhu; Fiscal Year: 2008
    ..Third, by targeting Asian language speakers this study addresses the issue of ethnic disparities, which has been identified by many (including the NCI Bypass Budget) as a research priority. ..
  35. Smoking Trajectories amid Waning State Program Budgets
    Lois Biener; Fiscal Year: 2008
    ..abstract_text> ..
  36. Drug craving: pharmacologic and associative influences
    Thomas Eissenberg; Fiscal Year: 2006
    ..Given the costs of smoking and the dramatic reduction in these costs when smokers quit smoking, improving the treatment options for all smokers is essential. ..
  37. The Bioavilaibility of Folate in Humans
    Richard van Breemen; Fiscal Year: 2004
    ..Our new LC-MS-MS assay and the use of 13C-labeled folate species will provide new and more detailed information on the uptake, metabolism, and bioavailability of folates than has been possible previously. ..
  38. STUDYING TOBACCO CONTROL POLICY IN MASSACHUSETTS
    MICHAEL BEGAY; Fiscal Year: 2002
    ..It is important for public health professionals to learn more about the obstacles to tobacco control policy. ..
  39. BUPROPION FOR HOSPITALIZED SMOKERS W CORONARY DISEASE
    Nancy Rigotti; Fiscal Year: 2002
    ..If found to be safe and effective, bupropion SR could become a standard part of "secondary prevention" therapy for smokers with acute CHD, a large, high-risk, high-cost patient group. ..
  40. Intracellular targeting of RNAs in virus infection
    Roger Beachy; Fiscal Year: 2004
    ..As the system being used involves a virus model system, the knowledge gained by this research may lead to novel therapies and transgenic approaches to control virus replication and disease. ..
  41. MOBILIZING PARENTS AND PEERS TO PREVENT TOBACCO USE
    Anthony Biglan; Fiscal Year: 2004
    ....
  42. MATRIX-ASSISTED LASER DESORPTION TOF MASS SPECTROMETER
    Richard van Breemen; Fiscal Year: 2001
    ..abstract_text> ..
  43. RURAL ELDERS: ETHNICITY, FOOD MEANING & DIET MEASUREMENT
    SARA QUANDT; Fiscal Year: 2004
    ..These participants will complete six 24 hour diet recall interviews over a six month period, which will be used to validate the adapted Food Frequency Questionnaire and Meal Pattern Questionnaire. ..
  44. Strutural basis of amyloid fiber pathology
    Ruben Diaz Avalos; Fiscal Year: 2003
    ..abstract_text> ..
  45. YOUTH SMOKING AND THE MEDIA
    Melanie Wakefield; Fiscal Year: 2003
    ..This study, by assessing the value of counteradvertising and media coverage in reducing smoking among youth, will guide health policy and health funding decisions related to youth smoking prevention. ..
  46. BUPROPION TREATMENT FOR YOUTH SMOKING CESSATION
    Myra Muramoto; Fiscal Year: 2001
    ..With so little research upon which to expand, the proposed study could lead to important new understandings regarding the process and mechanisms of youth smoking cessation. ..
  47. Predictors of Menarche
    Lindsay Frazier; Fiscal Year: 2004
    ..Understanding the predictors of menarche will help to develop a public health approach to the issue of early pubertal development. ..
  48. Community Based Training Models for Tobacco Cessations
    Myra Muramoto; Fiscal Year: 2005
    ..Phase IV: Dissemination study of the training model shown to be most effective though participating community partners. ..
  49. BODY TEMPERATURE AND REGULATING HOST DEFENSES
    Jeffrey Hasday; Fiscal Year: 2001
    ..abstract_text> ..
  50. ApoA-I Helical Domains and Cardiovascular Aging
    JOHN BIELICKI; Fiscal Year: 2005
    ..These studies are relevant for devising novel strategies to combat cardiovascular aging. ..
  51. FREE RADICALS IN MENTAL HEALTH & NEUROBIOLOGY
    Stephen Bondy; Fiscal Year: 2005
    ..The long-term support of this series of annual meetings will permit better planning for meeting organizers, attendees, students, and publishers. ..
  52. ALUMINUM/IRON INTERACTIONS IN NEURODEGENERATIVE DISEASE
    Stephen Bondy; Fiscal Year: 2005
    ..Together, these five objectives delineate a research strategy that will allow resolution of the seemingly contradictory evidence relating aluminum to neurological degeneration. ..
  53. MEASURING DEPENDENCE AND WITHDRAWAL IN TEEN SMOKERS
    Suzanne Colby; Fiscal Year: 2001
    ..Thus, it will provide a greater understanding of nicotine withdrawal as a maintaining factor of adolescent smoking, and thereby provide an empirical basis for enhancing smoking cessation approaches for youth. ..
  54. 2D-HPLC-Tandem Mass Spectrometer for Proteomics
    Richard van Breemen; Fiscal Year: 2005
    ..Overall, the proposed 2D mu LC-MS/MS instrument will complement the existing proteomics resources on campus and will enhance the current research of NIH-funded users by providing analytical capabilities currently unavailable on campus. ..
  55. EXTRAMURAL RESEARCH FACILITIES CONSTRUCTION
    Kenneth Warner; Fiscal Year: 2004
    ....
  56. GENES, DIET AND CARCINOGEN ACTIVATION IN SMOKERS
    Loic Le Marchand; Fiscal Year: 2004
    ..The elucidation of the main enzymes responsible for carcinogen activation and of the impact of dietary factors on these enzymes would have important implications for cancer prevention. ..
  57. PRESERVATION OF HDL FUNCTION DURING EARLY ATHEROGENESIS
    JOHN BIELICKI; Fiscal Year: 2002
    ..Moreover, the research will uncover novel mechanisms for preserving HDL/LCAT function that can be utilized therapeutically to fight the onset of cardiovascular disease. ..
  58. Imaging of nicotine sensitization in humans: a translational application of fMRI
    Joseph DiFranza; Fiscal Year: 2008
    ..The long-term goal is to use this new tool to see how addictive drugs alter the brain, and thereby identify targets for the development of new drugs to treat addiction. [unreadable] [unreadable] [unreadable]..
  59. Perception of Mechanical Stimuli by Arabidopsis Roots
    ROBYN PERRIN; Fiscal Year: 2004
    ..abstract_text> ..
  60. Development of a Web Based Tobacco Cessation Curriculum
    John Spangler; Fiscal Year: 2007
    ..The ultimate goal will be to develop a highly portable tobacco cessation curriculum that can be used a variety of educational settings. ..
  61. The Transition of Nicotine Dependence
    Joseph DiFranza; Fiscal Year: 2005
    ..A new theory-based measure of early dependence for youths will be tested against established measures of dependence. ..
  62. Expression of Human Therapeutic Proteins in Transgenic Tobacco Chloroplasts
    Henry Daniell; Fiscal Year: 2010
    ..Successful completion of these studies would make transgenic chloroplasts ideal bioreactors for the production of safe and less expensive therapeutic proteins and open the door for in depth studies of membrane proteins. ..
  63. Analysis of tobacco industry documents--Asia/Australia
    Simon Chapman; Fiscal Year: 2004
    ..abstract_text> ..