vitex

Summary

Summary: A genus of trees in the VERBENACEAE (sometimes classified in the LAMIACEAE) family containing assorted flavonoids with possible analgesic and antineoplastic properties. The fruit of these trees is used in herbal preparations.

Top Publications

  1. ncbi Isolation, characterization and biological activity of betulinic acid and ursolic acid from Vitex negundo L
    C Chandramu
    Department of Genetics, Osmania University, Hyderabad, India
    Phytother Res 17:129-34. 2003
  2. ncbi Tracheospasmolytic activity of viteosin-A and vitexicarpin isolated from vitex trifolia
    Gemini Alam
    Planta Med 68:1047-9. 2002
  3. ncbi Anti-inflammatory and analgesic activities of mature fresh leaves of Vitex negundo
    M G Dharmasiri
    Department of Zoology, University of Colombo, 3, Colombo, Sri Lanka
    J Ethnopharmacol 87:199-206. 2003
  4. ncbi An experimental evaluation of anticonvulsant activity of Vitex-negundo
    V R Tandon
    Post Graduate Department of Pharmacology and Therapeutics, Govt Medical College, Jammu 180 001
    Indian J Physiol Pharmacol 49:199-205. 2005
  5. ncbi Vitex negundo modulates selenite-induced opacification and cataractogensis in rat pups
    B N Rooban
    Department of Biochemistry, University of Kerala, Kariavattom, Thiruvananthapuram, 695581 Kerala, India
    Biol Trace Elem Res 138:282-92. 2010
  6. ncbi Evaluation of leaf extracts of Vitex negundo L. (Family: Verbenaceae) against larvae of Culex tritaeniorhynchus and repellent activity on adult vector mosquitoes
    Kaliyaperumal Karunamoorthi
    Unit of Vector Biology and Control, School of Environmental Health Science, Faculty of Public Health, Jimma University, Jimma, Ethiopia
    Parasitol Res 103:545-50. 2008
  7. ncbi Inhibition of melanogenesis versus antioxidant properties of essential oil extracted from leaves of Vitex negundo Linn and chemical composition analysis by GC-MS
    Huey Chun Huang
    Department of Medical Laboratory Science and Biotechnology, China Medical University, No 91 Hsueh Shih Road, Taichung City 40402, Taiwan
    Molecules 17:3902-16. 2012
  8. ncbi Mosquito larvicidal activity of methyl-p-hydroxybenzoate isolated from the leaves of Vitex trifolia Linn
    K Kannathasan
    Department of Botany, Annamalai University, Annamalai Nagar 608 002, Tamil Nadu, India
    Acta Trop 120:115-8. 2011
  9. ncbi Estrogen-like activity of volatile components from Vitex rotundifolia L
    Yuan Hu
    Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China
    Indian J Med Res 126:68-72. 2007
  10. ncbi Snake venom neutralization by Indian medicinal plants (Vitex negundo and Emblica officinalis) root extracts
    M I Alam
    Department of Physiology, Acharya Shri Chander College of Medical Sciences and Hospital, Sidhra, Jammu 180006, India
    J Ethnopharmacol 86:75-80. 2003

Detail Information

Publications168 found, 100 shown here

  1. ncbi Isolation, characterization and biological activity of betulinic acid and ursolic acid from Vitex negundo L
    C Chandramu
    Department of Genetics, Osmania University, Hyderabad, India
    Phytother Res 17:129-34. 2003
    ..3), and ursolic acid (2beta-hydroxyurs-12-en-28-oic acid) (4), were isolated for the first time from leaves of Vitex negundo L...
  2. ncbi Tracheospasmolytic activity of viteosin-A and vitexicarpin isolated from vitex trifolia
    Gemini Alam
    Planta Med 68:1047-9. 2002
    ..3 x 10(-5) M. The result suggests that vitexicarpin is able to block effects of histamine released from sensitized mast cells possibly by stabilizing the mast cells membrane function...
  3. ncbi Anti-inflammatory and analgesic activities of mature fresh leaves of Vitex negundo
    M G Dharmasiri
    Department of Zoology, University of Colombo, 3, Colombo, Sri Lanka
    J Ethnopharmacol 87:199-206. 2003
    ..study confirmed the oral anti-inflammatory, analgesic and antihistamine properties of mature fresh leaves (MFL) of Vitex negundo L. (Verbenaceae) claimed in the Ayurveda medicine by orally treating a water extract of the leaves to rats...
  4. ncbi An experimental evaluation of anticonvulsant activity of Vitex-negundo
    V R Tandon
    Post Graduate Department of Pharmacology and Therapeutics, Govt Medical College, Jammu 180 001
    Indian J Physiol Pharmacol 49:199-205. 2005
    ..rats and pentylenetetarazole (PTZ) induced seizures in albino mice were used to study anticonvulsant activity of Vitex-negundo leaf extract...
  5. ncbi Vitex negundo modulates selenite-induced opacification and cataractogensis in rat pups
    B N Rooban
    Department of Biochemistry, University of Kerala, Kariavattom, Thiruvananthapuram, 695581 Kerala, India
    Biol Trace Elem Res 138:282-92. 2010
    ..The goal of this study was to determine the efficacy of Vitex negundo in modulating the selenite-induced oxidative stress in vivo model...
  6. ncbi Evaluation of leaf extracts of Vitex negundo L. (Family: Verbenaceae) against larvae of Culex tritaeniorhynchus and repellent activity on adult vector mosquitoes
    Kaliyaperumal Karunamoorthi
    Unit of Vector Biology and Control, School of Environmental Health Science, Faculty of Public Health, Jimma University, Jimma, Ethiopia
    Parasitol Res 103:545-50. 2008
    Petroleum ether (60-80 degrees C) extracts of the leaves of Vitex negundo (Verbenaceae) were evaluated for larvicidal activity against larval stages of Culex tritaeniorhynchus in the laboratory. Larvae of C...
  7. ncbi Inhibition of melanogenesis versus antioxidant properties of essential oil extracted from leaves of Vitex negundo Linn and chemical composition analysis by GC-MS
    Huey Chun Huang
    Department of Medical Laboratory Science and Biotechnology, China Medical University, No 91 Hsueh Shih Road, Taichung City 40402, Taiwan
    Molecules 17:3902-16. 2012
    ..negundo Linn leaves decreased melanin production in B16F10 melanoma cells and showed potent antioxidant activities. The essential oil can thereby serve as an inhibitor of melanin synthesis and could also act as a natural antioxidant...
  8. ncbi Mosquito larvicidal activity of methyl-p-hydroxybenzoate isolated from the leaves of Vitex trifolia Linn
    K Kannathasan
    Department of Botany, Annamalai University, Annamalai Nagar 608 002, Tamil Nadu, India
    Acta Trop 120:115-8. 2011
    ..In the present study, a crystalline compound methyl-p-hydroxybenzoate was isolated from the methanol extract of Vitex trifolia leaves and it was identified by (1)H and (13)C NMR and single crystal X-ray diffractometer...
  9. ncbi Estrogen-like activity of volatile components from Vitex rotundifolia L
    Yuan Hu
    Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China
    Indian J Med Res 126:68-72. 2007
    The fruits of Vitex rotundifolia L. are used as a traditional medicine in China. Dried fruits of V. rotundifolia (rich in essential oils) have been known to show strong estrogenic activity...
  10. ncbi Snake venom neutralization by Indian medicinal plants (Vitex negundo and Emblica officinalis) root extracts
    M I Alam
    Department of Physiology, Acharya Shri Chander College of Medical Sciences and Hospital, Sidhra, Jammu 180006, India
    J Ethnopharmacol 86:75-80. 2003
    The methanolic root extracts of Vitex negundo Linn. and Emblica officinalis Gaertn. were explored for the first time for antisnake venom activity. The plant (V. negundo and E...
  11. ncbi Anti-microfilarial activity of methanolic extract of Vitex negundo and Aegle marmelos and their phytochemical analysis
    K N Sahare
    P G Department of Microbiology and Rajiv Gandhi Biotechnology Centre, RTM, Nagpur University, Nagpur 440 033, India
    Indian J Exp Biol 46:128-31. 2008
    In the present study, methanolic extracts of roots of Vitex negundo L. and extracts of leaves of Vitex negundo L., Ricinus communis L. and Aegle marmelos Corr...
  12. ncbi Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo
    Fredyc Diaz
    Program for Collaborative Research in the Pharmaceutical Sciences and Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Nat Prod 66:865-7. 2003
    Bioassay-guided fractionation of the chloroform-soluble extract of the leaves of Vitex negundo led to the isolation of the known flavone vitexicarpin (1), which exhibited broad cytotoxicity in a human cancer cell line panel...
  13. ncbi alpha-Chymotrypsin inhibition studies on the lignans from Vitex negundo Linn
    Muhammad Arif Lodhi
    Dr Panjwani Center for Molecular Medicine and Drug Research, University of Karachi, Karachi 75270, Pakistan
    J Enzyme Inhib Med Chem 23:400-5. 2008
    The lignans (1-8) isolated from the roots of Vitex negundo Linn. were screened against the serine proteases alpha-chymotrypsin, thrombin and prolyl endopeptidase...
  14. ncbi A Vitex agnus-castus extract inhibits cell growth and induces apoptosis in prostate epithelial cell lines
    M Weisskopf
    Institute of Pharmaceutical Biology, University of Basel, Schonbeinstrasse 40, 4003 Basel, Switzerland
    Planta Med 71:910-6. 2005
    Extracts of Vitex agnus-castus fruits (VACF) are described to have beneficial effects on disorders related to hyperprolactinemia (cycle disorders, premenstrual syndrome)...
  15. ncbi Activation of the mu-opiate receptor by Vitex agnus-castus methanol extracts: implication for its use in PMS
    D E Webster
    Department of Biopharmaceutical Sciences, College of Pharmacy, 833 South Woods Street, Room 335, University of Illinois, Chicago, IL 60612, USA
    J Ethnopharmacol 106:216-21. 2006
    The dried ripe fruit of Vitex agnus-castus L. (VAC) is widely used for the treatment of premenstrual syndrome (PMS)...
  16. ncbi Vascular protective role of vitexicarpin isolated from Vitex rotundifolia in human umbilical vein endothelial cells
    So Min Lee
    College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Chonbuk 570 749, Republic of Korea
    Inflammation 35:584-93. 2012
    ..Recent pharmacological studies have demonstrated that vitexicarpin, a flavonoid isolated from Vitex rotundifolia, has anti-inflammatory, antitumor, and analgesic properties...
  17. ncbi Reproduction in male rats is vulnerable to treatment with the flavonoid-rich seed extracts of Vitex negundo
    Suwagmani Das
    Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee 247 667, Uttaranchal, India
    Phytother Res 18:8-13. 2004
    A partially purified flavonoid-rich extract was prepared from the seed of Vitex negundo. The effect of this extract on the reproductive system of male rats was investigated at four different concentrations...
  18. ncbi Larvicidal activity of fatty acid methyl esters of Vitex species against Culex quinquefasciatus
    Krishnan Kannathasan
    Department of Botany, Annamalai University, Annamalai Nagar 608 002, Tamil Nadu, India
    Parasitol Res 103:999-1001. 2008
    The larvicidal activity of fatty acid methyl ester (FAME) extracts of Vitex altissima, Vitex negundo and Vitex trifolia was studied against early fourth-instar larvae of Culex quinquefasciatus...
  19. ncbi Enzyme inhibiting lignans from Vitex negundo
    - Azhar-Ul-Haq
    International Centre for Chemical Sciences, H E J Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan
    Chem Pharm Bull (Tokyo) 52:1269-72. 2004
    ..The structures of the new compounds were established through spectral studies. Compound 2 showed potent inhibitory activity against lipoxygenase enzyme, while 5 showed moderate activity against butyryl-cholinesterase...
  20. ncbi New norditerpenoids with trypanocidal activity from Vitex trifolia
    Fumiyuki Kiuchi
    Tsukuba Medicinal Plant Research Station, National Institute of Health Sciences, Hachiman dai, Tsukuba, Japan
    Chem Pharm Bull (Tokyo) 52:1492-4. 2004
    Trypanocidal constituents of the fruits of Vitex trifolia were investigated...
  21. ncbi [Vitexicarpin, a flavonoid from Vitex trifolia L., induces apoptosis in K562 cells via mitochondria-controlled apoptotic pathway]
    Hai Yan Wang
    Tianjin Institute for Biomedicinal Research, Tianjin 300384, China
    Yao Xue Xue Bao 40:27-31. 2005
    ..To investigate the inhibitory effect of vitexicarpin on the proliferation of human cancer cells and its mechanism of action...
  22. ncbi Human gastric signet ring carcinoma (KATO-III) cell apoptosis induced by Vitex agnus-castus fruit extract through intracellular oxidative stress
    Kunio Ohyama
    Department of Clinical Molecular Genetics, Faculty of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Tokyo 192 0355, Japan
    Int J Biochem Cell Biol 37:1496-510. 2005
    We have previously reported that an ethanol extract of the dried ripe fruit of Vitex agnus-castus (Vitex) displays cytotoxic activity against certain kinds of human cancer cell line resulting in the induction of apoptosis...
  23. ncbi Hepatoprotective activity of Vitex negundo leaf extract against anti-tubercular drugs induced hepatotoxicity
    Vishal R Tandon
    Post Graduate Department of Pharmacology and Therapeutics, Govt Medical College Jammu J and K, 180001 India
    Fitoterapia 79:533-8. 2008
    Hepatoprotective (HP) activity of Vitex negundo (VN) leaf ethanolic extract was investigated against hepatotoxicity (HT) produced by administering a combination of three anti-tubercular drugs isoniazid (INH)-7...
  24. ncbi Pentacyclic triterpenoids and ceramide mediate the vasorelaxant activity of Vitex cienkowskii via involvement of NO/cGMP pathway in isolated rat aortic rings
    Alain Bertrand Dongmo
    Department of Animal Biology, Faculty of Science, University of Douala, Douala, Cameroon
    J Ethnopharmacol 133:204-12. 2011
    b>Vitex cienkowskii Kotschy & Peyritsch is a deciduous tree, prescribed by Cameroonian traditional healers as one of the most popular plant widely used in many disorders including cardiovascular diseases...
  25. ncbi Antinociceptive activities of the liposoluble fraction from Vitex negundo seeds
    Cheng Jian Zheng
    Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai, PR China
    Pharm Biol 48:651-8. 2010
    The antinociceptive activities of the petroleum ether fraction (PEF) from the aqueous ethanol extract of Vitex negundo Linn. (Verbenaceae) seeds have been evaluated in several nociceptive mouse models...
  26. ncbi Antitussive and toxicological evaluation of Vitex negundo
    Rizwan Ul Haq
    Institute of Neurophysiology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Nat Prod Res 26:484-8. 2012
    b>Vitex negundo Linn. (Verbenaceae) is used in traditional medical system for respiratory disorders. This study was carried out to investigate its cough-relieving potential. The antitussive effect of the butanolic extract of V...
  27. pmc Negundoside, an irridiod glycoside from leaves of Vitex negundo, protects human liver cells against calcium-mediated toxicity induced by carbon tetrachloride
    Sheikh A Tasduq
    Experimental Toxicology Lab, Division of Pharmacology, Indian Institute of Integrative Medicine, CSIR, Canal Road, Jammu 180001, Jammu and Kashmir, India
    World J Gastroenterol 14:3693-709. 2008
    ..To evaluate the protective effect of 2'-p-hydroxybenzoylmussaenosidic acid [negundoside (NG), against carbon tetrachloride (CCl(4))-induced toxicity in HuH-7 cells...
  28. ncbi Vitex agnus castus as prophylaxis for osteopenia after orchidectomy in rats compared with estradiol and testosterone supplementation
    S Sehmisch
    Department of Trauma and Reconstructive Surgery, Georg August University of Goettingen, Goettingen, Germany
    Phytother Res 23:851-8. 2009
    ..The groups either received soy-free food (C), estradiol (E), testosterone (T) or Vitex agnus castus in different concentrations (AC high/AC low) for 12 weeks...
  29. ncbi Evaluation of the estrogenic activity of the constituents in the fruits of Vitex rotundifolia L. for the potential treatment of premenstrual syndrome
    Yuan Hu
    Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China
    J Pharm Pharmacol 59:1307-12. 2007
    The ethanol extract of the fruits of Vitex rotundifolia (VRE) and its four major compounds (casticin, luteolin, rotundifuran and agnuside) were tested for their estrogen-like activity by using the modified cell proliferation assay (E-..
  30. ncbi Antiseptic activity and phenolic constituents of the aerial parts of Vitex negundo var. cannabifolia
    Tie Jun Ling
    Key Laboratory of Tea Biochemistry and Biotechnology of Ministry of Education and Ministry of Agriculture, Anhui Agricultural University, 130 West Changjiang Road, Hefei 230036, China
    Molecules 15:8469-77. 2010
    ..and isovitexin (5), along with α-tocoquinone (3) and β-sitosterol (6) were isolated from the aerial parts of Vitex negundo var. cannabifolia. The isolation was performed using bio-assay tracking experiments...
  31. ncbi Association between chemical and genetic variation of Vitex rotundifolia populations from different locations in China: its implication for quality control of medicinal plants
    Yuan Hu
    Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, People s Republic of China
    Biomed Chromatogr 21:967-75. 2007
    b>Vitex rotundifolia is a widely distributed plant species that has been extensively used in traditional Chinese medicine. Its fruits, Fructus Viticis, are recorded as Manjingzi in the Pharmacopoeia of the People's Republic of China...
  32. ncbi Compounds from Vitex polygama active against kidney diseases
    Margareth B C Gallo
    Departamento de Quimica, Universidade Federal de Sao Carlos, 13565 905 Sao Carlos, Sao Paulo, Brazil
    J Ethnopharmacol 115:320-2. 2008
    b>Vitex polygama Cham. (Lamiaceae, formerly Verbenaceae) is a familiar Brazilian species popularly known as Tarumã whose leaf tea has been used by population to treat kidney diseases...
  33. ncbi Activity of aqueous extract of the bark of Vitex doniana on uterine muscle response to drugs
    Olusola Ladeji
    Department of Biochemistry, Faculty of Medical Sciences, University of Jos, Nigeria
    Phytother Res 19:804-6. 2005
    The activity of Vitex doniana on the uterine muscle response was investigated. The bark of Vitex doniana was extracted in boiled water at 100 degrees C, and the extracted solution filtered and centrifuged with refrigeration...
  34. ncbi Antinociceptive activity of Vitex-negundo Linn leaf extract
    R K Gupta
    Department of Pharmacology, M G I M S Sevagram, Wardha 442 102
    Indian J Physiol Pharmacol 49:163-70. 2005
    ..acid induced writhing in mice were employed to study the antinociceptive activity of ethanolic leaf extract of Vitex-negundo (VN) (100, 250 and 500 mg/kg, p.o)...
  35. ncbi Diterpenoids and flavonoids from the fruits of Vitex agnus-castus and antioxidant activity of the fruit extracts and their constituents
    Zsuzsanna Hajdú
    Department of Pharmacognosy, University of Szeged, H 6720 Szeged, Hungary
    Phytother Res 21:391-4. 2007
    From the n-hexane fraction of the fruits of Vitex agnus-castus, two labdane-type diterpenes, vitetrifolin B and C, were isolated by means of multiple chromatographic separations, together with the previously identified rotundifuran, ..
  36. ncbi Vitex negundo attenuates calpain activation and cataractogenesis in selenite models
    B N Rooban
    Department of Biochemistry, University of Kerala, Kariavattom, Thiruvananthapuram, Kerala, India
    Exp Eye Res 88:575-82. 2009
    ..Our present study focuses on the isolation of flavonoids from Vitex negundo and to assess its efficacy in preventing these changes in the lens of selenite-induced cataract models...
  37. ncbi Ecdysteroids from Vitex species: distribution and compilation of their 13C-NMR spectral data
    José G Sena Filho
    Universidade Federal da Paraiba, Laboratorio de Tecnologia Farmaceutica, Caixa Postal 5009, 58051 970, Joao Pessoa, PB, Brazil
    Chem Biodivers 5:707-13. 2008
    ..The present work describes the distribution of ecdysteroids in plants from the genus Vitex from a review of previous work on seventeen Vitex species...
  38. ncbi Anti-inflammatory and enzyme inhibitory activities of a crude extract and a pterocarpan isolated from the aerial parts of Vitex agnus-castus
    Bashir Ahmad
    Center for Biotechnology and Microbiology University of Peshawar, Peshawar, Pakistan
    Biotechnol J 5:1207-15. 2010
    ..benzofuro [3,2-c][1,3]dioxolo[4,5-g]chromen-9-ol was isolated from the ethyl acetate fraction of Vitex agnus-castus...
  39. ncbi Fluoxetine versus Vitex agnus castus extract in the treatment of premenstrual dysphoric disorder
    Murad Atmaca
    Firat University, School of Medicine, Department of Psychiatry, Elazig, Turkey
    Hum Psychopharmacol 18:191-5. 2003
    Clinical trials have demonstrated that serotonin reuptake inhibitors (SRIs) and the extract of Vitex agnus castus are effective for the treatment of premenstrual dysphoric disorder (PMDD)...
  40. ncbi Tyrosinase inhibitory lignans from the methanol extract of the roots of Vitex negundo Linn. and their structure-activity relationship
    - Azhar-Ul-Haq
    International Center for Chemical Sciences, H E J Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan
    Phytomedicine 13:255-60. 2006
    Phytochemical investigation of the methanol extract of Vitex negundo afforded eight lignans; negundin A 1, negundin B 2, 6-hydroxy-4-(4-hydroxy-3-methoxy)-3-hydroxymethyl-7-methoxy-3,4-dihydro-2-naphthaledehyde 3, vitrofolal E 4, (+)-..
  41. ncbi Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry)
    J Liu
    Department of Medicinal Chemistry and Pharmacognosy, UIC NIH Center for Botanical Dietary Supplements Research, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Phytomedicine 11:18-23. 2004
    A methanol extract of chaste-tree berry (Vitex agnus-castus L.) was tested for its ability to displace radiolabeled estradiol from the binding site of estrogen receptors alpha (ERalpha) and beta (ERbeta)...
  42. ncbi Vitex agnus castus: a systematic review of adverse events
    Claudia Daniele
    Department of Pharmacology of Natural Substances and General Physiology, University of Rome La Sapienza, Rome, Italy
    Drug Saf 28:319-32. 2005
    b>Vitex agnus castus L. (VAC) [Verbenaceae] is a deciduous shrub that is native to Mediterranean Europe and Central Asia...
  43. ncbi Bioactivity of extracts and isolated compounds from Vitex polygama (Verbenaceae) and Siphoneugena densiflora (Myrtaceae) against Spodoptera frugiperda (Lepidoptera: Noctuidae)
    Margareth B C Gallo
    Departamento de Quimica, Universidade Federal de Sao Carlos UFSCar, CP 676, 13565 905, Sao Carlos SP, Brazil
    Pest Manag Sci 62:1072-81. 2006
    The effects of crude extracts, fractions and isolated compounds from Vitex polygama Cham...
  44. ncbi Evidence for estrogen receptor beta-selective activity of Vitex agnus-castus and isolated flavones
    Hubertus Jarry
    Klinische und Experimentelle Endokrinologie, Universitätsfrauenklinik Göttingen, Gottingen, Germany
    Planta Med 69:945-7. 2003
    Recent cell culture experiments indicated that extracts of Vitex agnus-castus (VAC) may contain yet unidentified phytoestrogens. Estrogenic actions are mediated via estrogen receptors (ER)...
  45. ncbi [Effectiveness of Vitex agnus-castus preparations]
    C Gorkow
    Medizinischen Forschung von Bionorica AG, Kerschensteinerstrasse 11 15, D 92318 Neumarkt Opf, Deutschland
    Wien Med Wochenschr 152:364-72. 2002
    ..The success rates on fertility disorders should be confirmed in controlled double-blind studies (10, 33, 34)...
  46. ncbi G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.)
    Junko Kobayakawa
    Hyogo Institute for Oriental Medicine, Higashidaimotsu cho, Hyogo 660 0828, Japan
    Cancer Lett 208:59-64. 2004
    ..Further examinations are required to confirm that casticin is an antitumor drug for specific cancers with low toxicity...
  47. ncbi Extract of the seeds of the plant Vitex agnus castus proven to be highly efficacious as a repellent against ticks, fleas, mosquitoes and biting flies
    Heinz Mehlhorn
    Department of Cytology, Zoomorphology and Parasitology, Heinrich Heine University, Dusseldorf, Germany
    Parasitol Res 95:363-5. 2005
    ..It was found that a CO2 extract of the seeds of the Mediterranean plant Vitex agnus castus (monk's pepper) can be used as a spray to keep away especially Ixodes ricinus and Rhipicephalus ..
  48. ncbi Pharmacological activities of Vitex agnus-castus extracts in vitro
    B Meier
    Zeller AG, Herbal Medicinal Products, Romanshorn, Switzerland
    Phytomedicine 7:373-81. 2000
    The pharmacological effects of ethanolic Vitex agnus-castus fruit-extracts (especially Ze 440) and various extract fractions of different polarities were evaluated both by radioligand binding studies and by superfusion experiments...
  49. ncbi Vitex agnus castus essential oil and menopausal balance: a research update [Complementary Therapies in Nursing and Midwifery 8 (2003) 148-154]
    Barbara Chopin Lucks
    Complement Ther Nurs Midwifery 9:157-60. 2003
    The first trial of two essential oils (derived separately from leaf and fruit) of Vitex agnus castus for menopausal balance was conducted in the summer of 2000 by the author...
  50. ncbi Hypericum perforatum with Vitex agnus-castus in menopausal symptoms: a randomized, controlled trial
    M Diana van Die
    Royal Melbourne Institute of Technology University, Victoria, Australia
    Menopause 16:156-63. 2009
    To evaluate the effectiveness of a phytotherapeutic intervention comprising a combination of Hypericum perforatum (St. John's wort) and Vitex agnus-castus (Chaste tree/berry) in the management of menopausal symptoms.
  51. ncbi Effects of a combination of Hypericum perforatum and Vitex agnus-castus on PMS-like symptoms in late-perimenopausal women: findings from a subpopulation analysis
    Margaret Diana van Die
    Royal Melbourne Institute of Technology University, Bundoora, Victoria, Australia
    J Altern Complement Med 15:1045-8. 2009
    ....
  52. ncbi Chaste tree (Vitex agnus-castus)--pharmacology and clinical indications
    W Wuttke
    Department of Clinical and Experimental Endocrinology, University of Gottingen, Germany
    Phytomedicine 10:348-57. 2003
    Extracts of the fruits of chaste tree (Vitex agnus castus = AC) are widely used to treat premenstrual symptoms. Double-blind placebo-controlled studies indicate that one of the most common premenstrual symptoms, i.e...
  53. ncbi Cytotoxicity and apoptotic inducibility of Vitex agnus-castus fruit extract in cultured human normal and cancer cells and effect on growth
    Kunio Ohyama
    Department of Biochemistry, Faculty of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Tokyo 192 0355, Japan
    Biol Pharm Bull 26:10-8. 2003
    A crude extract was prepared with ethanol from dried ripened Vitex agnus-castus fruits growing in Israel (Vitex extract)...
  54. ncbi Vitex negundo Linn (VN) leaf extract as an adjuvant therapy to standard anti-inflammatory drugs
    Vishal R Tandon
    Postgraduate Department of Pharmacology and Therapeutics, Government Medical College, Jammu, India
    Indian J Med Res 124:447-50. 2006
    Leaves of Vitex negundo (VN) have been investigated for their antiinflammatory activity in past, including its mechanism of action. However, nobody has evaluated its potential role as an adjuvant with standard anti-inflammatory therapy...
  55. ncbi An integrative medicine approach to premenstrual syndrome
    Andrea Girman
    Continuum Center for Health and Healing, New York, NY 10016, USA
    Am J Obstet Gynecol 188:S56-65. 2003
    ..This review will be relevant to the practicing clinician seeking to become aware of and to understand the relevance of the complementary/alternative therapies being used by his/her patients for PMS and PMDD...
  56. ncbi Iridoids with anti-inflammatory activity from Vitex peduncularis
    A Suksamrarn
    Department of Chemistry, Ramkhamhaeng University, Bangkok, Thailand
    Planta Med 68:72-3. 2002
    A new iridoid, pedunculariside, together with the known iridoid agnuside were isolated from the butanol extract of Vitex peduncularis stem bark...
  57. ncbi New antifungal flavonoid glycoside from Vitex negundo
    B Sathiamoorthy
    Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow 226 001, India
    Bioorg Med Chem Lett 17:239-42. 2007
    ..Our bioactivity guided fractionation of ethanolic extract of leaves of Vitex negundo resulted in the isolation of new flavone glycoside (4) along with five known compounds 1-3, 5 and 6...
  58. ncbi Evaluation of five medicinal plants used in diarrhoea treatment in Nigeria
    Abdulkarim Agunu
    Department of Pharmacognosy and Drug Development, Ahmadu Bello University, Zaria, Nigeria
    J Ethnopharmacol 101:27-30. 2005
    Five medicinal plants [Acacia nilotica, Acanthospermun hispidum, Gmelina arborea, Parkia biglobosa and Vitex doniana] used in diarrhoeal treatment in Kaduna State, Nigeria, were investigated...
  59. ncbi Insecticidal activity of Vitex mollis
    V Rodríguez-López
    Facultad de Farmacia, Universidad Autonoma del Estado de Morelos, Avenida Universidad 1001, Colonia Chamilpa, Cuernavaca Morelos 6209, Mexico
    Fitoterapia 78:37-9. 2007
    Organic extracts from the leaves of Vitex mollis were assessed for their toxic effect on fall armyworm neonate larvae (Spodoptera frugiperda), an important insect pest of corn...
  60. ncbi Vitex agnus castus might enrich the pharmacological armamentarium for medical treatment of prolactinoma
    Gianluca Tamagno
    Eur J Obstet Gynecol Reprod Biol 135:139-40. 2007
  61. ncbi Antitoxin activity of plants used in Mexican traditional medicine against scorpion poisoning
    J E Jiménez-Ferrer
    Instituto Mexicano del Seguro Social IMSS, Centro de Investigacion Biomedica del Sur, Argentina 1, 62790 Xochitepec, Morelos, Mexico
    Phytomedicine 12:116-22. 2005
    ..The aim of this work was to evaluate the effect of Bouvardia ternifolia, Aristolochia elegans and Vitex mollis extracts on Centruroides limpidus limpidus venom lethality in mice, and to determine their antagonist ..
  62. ncbi A prolactinoma masked by a herbal remedy
    Joseph Gallagher
    Eur J Obstet Gynecol Reprod Biol 137:257-8. 2008
  63. ncbi Anti-nociceptive and anti-hyperprolactinemia activities of Fructus Viticis and its effective fractions and chemical constituents
    Y Hu
    Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, PR China
    Phytomedicine 14:668-74. 2007
    b>Vitex rotundifolia L. is widely distributed along the sea coast of China...
  64. ncbi Phyto-Female Complex for the relief of hot flushes, night sweats and quality of sleep: randomized, controlled, double-blind pilot study
    Carmela Rotem
    Felsenstein Medical Research Center, Beilinson Campus, Petah Tiqva, Israel
    Gynecol Endocrinol 23:117-22. 2007
    ....
  65. ncbi Effects of luteolin on the inhibition of proliferation and induction of apoptosis in human myeloid leukaemia cells
    W G Ko
    College of Pharmacy and Medicinal Resources Research Center, Wonkwang University, Iksan, Jeonbuk, Korea
    Phytother Res 16:295-8. 2002
    Luteolin, a flavonoid isolated from the fruit of Vitex rotundifolia, has been examined with regard to the inhibition of proliferation and induction of apoptosis in human myeloid leukaemia HL-60 cells...
  66. ncbi Effect of crude extract and fractions from Vitex megapotamica leaves on hyperglycemia in alloxan-diabetic rats
    Leila Zanatta
    Departamento de Bioquimica, Centro de Ciencias Biologicas, Universidade Federal de Santa Catarina, Cx Postal 5069, CEP 88040 970 Florianópolis, SC, Brazil
    J Ethnopharmacol 109:151-5. 2007
    The effect of the crude extract, ethyl acetate and n-butanol fractions from Vitex megapotamica (Spreng) Moldenke on glycemia was investigated in diabetic rats...
  67. ncbi Phenolic compounds and flavonoids as plant growth regulators from fruit and leaf of Vitex rotundifolia
    Takeo Yoshioka
    Course of Applied Resource Science, The United Graduate School of Agricultural Sciences, Tottori University, Koyama, Tottori shi, Tottori 680 8553, Japan
    Z Naturforsch C 59:509-14. 2004
    ..6), luteolin (7), vitexicarpin (8) and artemetin (9), were isolated from fruits and leaves of Vitex rotundifolia L...
  68. ncbi Two new lignan glucosides from the fruit of Vitex cannabifolia
    Toru Yamasaki
    School of Agriculture, Kyushu Tokai University, 5435 Minamiaso, Aso, Kumamoto, 869 1404, Japan
    J Nat Med 62:47-51. 2008
    ..phenyldihydronaphthalene-type lignan glucosides, vitecannasides A (1) and B (2) were isolated from the fruit of Vitex cannabifolia Sieb. et. Zucc...
  69. ncbi Herbs commonly used by women: an evidence-based review
    Bonnie J Tesch
    Dis Mon 48:671-96. 2002
    ..To review the evidence of herbs commonly used by women...
  70. ncbi The effects of phytoestrogens on fracture healing: experimental research in New Zealand white rabbits
    Alpaslan Oztürk
    Department of Orthopaedics and Traumatology, Bursa High Speciality Research and Training Hospital, Bursa, Turkey
    Ulus Travma Acil Cerrahi Derg 14:21-7. 2008
    ..Phytoestrogens are plant-derived natural molecules having some bone forming and bone substituting effects. In the present study, the role of phytoestrogens on bone healing was investigated in a rabbit fracture model...
  71. ncbi Chasteberry
    Beatrix Roemheld-Hamm
    Department of Family Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, USA
    Am Fam Physician 72:821-4. 2005
    ..No herb-drug interactions have been reported, but caution is advised for its concomitant use with dopamine agonists or antagonists. Optimal standardization and dosing recommendations await clarification in clinical studies...
  72. ncbi Effect of biopesticides on the lactate dehydrogenase (LDH) of the rice leaffolder, Cnaphalocrocis medinalis (Guenée) (Insecta: Lepidoptera: Pyralidae)
    Sengottayan Senthil Nathan
    Department of Environmental Engineering, Chonbuk National University, Jeonju City, Chonbuk 561 756, South Korea
    Ecotoxicol Environ Saf 65:102-7. 2006
    The effects of bacterial toxins (Bacillus thuringiensis) and botanical insecticides (Azadirachta indica and Vitex negundo) on lactate dehydrogenase (LDH) activity in Cnaphalocrocis medinalis (Guenée) (the rice leaffolder) were evaluated...
  73. ncbi [Toxicity and oviposition-deterrence of Vitex negundo extracts to Plutella xylostella]
    Lin Yuan
    Department of Entomology, College of Plant Protection, Shandong Agricultural University, Taian 271018, China
    Ying Yong Sheng Tai Xue Bao 17:695-8. 2006
    This paper studied the toxicity of dichloromethane-petroleum ether-and methanol extracts from Vitex negundo seed and leaf to the 2nd and 4th instar larvae of Plutella xylostella, and the oviposition-deterrence effects of these extracts ..
  74. ncbi Combined effect of biopesticides on the digestive enzymatic profiles of Cnaphalocrocis medinalis (Guenée) (the rice leaffolder) (Insecta: Lepidoptera: Pyralidae)
    Sengottayan Senthil Nathan
    Department of Environmental Engineering, Chonbuk National University, Jeonju City, Chonbuk 561 756, South Korea
    Ecotoxicol Environ Saf 64:382-9. 2006
    ..A synergistic effect of botanical insecticides and bacterial toxins was found when combined in low doses. These effects are most pronounced in early instars...
  75. ncbi Are extraction methods in quantitative assays of pharmacopoeia monographs exhaustive? A comparison with pressurized liquid extraction
    Carlos Basalo
    Institute of Pharmaceutical Biology, University of Basel, Basel, Switzerland
    Planta Med 72:1157-62. 2006
    ..PLE was in all cases superior to the extraction protocol of the pharmacopoeia monographs (taken as 100 %), with differences ranging from 108 % in case of parthenolide in Tanaceti herba to 343 % in case of alkaloids in Boldo folium...
  76. ncbi Mutagenicity and antimutagenicity of teas used in popular medicine in the salmonella/microsome assay
    Rubem Cesar Horn
    Departamento de Laboratorios, Laboratório de Análises Moleculares e Mutagênese Ambiental, Fundação Estadual de Proteção Ambiental Henrique Luís Roessler, Av Dr Salvador França, 1707, CEP 90690 000 Porto Alegre RS, Brazil
    Toxicol In Vitro 22:1043-9. 2008
    ..Mutagenic and antimutagenic activities of three plant species, Vitex montevidensis Cham. (Lamiaceae), Gochnatia cordata Less. (Asteraceae) and G...
  77. ncbi Systematic analysis of in vitro photo-cytotoxic activity in extracts from terrestrial plants in Peninsula Malaysia for photodynamic therapy
    Cheng Yi Ong
    Cancer Research Initiatives Foundation CARIF, Subang Jaya Medical Centre, 1, Jalan SS12 1A, 47500 Subang Jaya, Selangor Darul Ehsan, Malaysia
    J Photochem Photobiol B 96:216-22. 2009
    ..Entada phaseoloides and Leucaena leucocephala (Leguminosae), Oroxylum indicum (Bignoniaceae), Peronema canescens,Vitex pubescens and Premna odorata (Verbenaceae), Piper mucronatum and Piper sp...
  78. pmc In vitro screening for the tumoricidal properties of international medicinal herbs
    Elizabeth A Mazzio
    College of Pharmacy and Pharmaceutical Sciences, Florida A and M University, Tallahassee, Florida 32307, USA
    Phytother Res 23:385-98. 2009
    ..Berberidaceae) > Dryopteris crassirhizoma (Dryopteridaceae) > Garcinia cambogia (Clusiaceae) > Vitex agnus-castus (Verbenaceae) > Calamus draco (Arecaceae)...
  79. ncbi The evaluation of nitric oxide scavenging activity of certain Indian medicinal plants in vitro: a preliminary study
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, Karnataka, India
    J Med Food 7:343-8. 2004
    ..gt; Phyllanthus niruri > Ocimum sanctum > Tinospora cordifolia (hexane extract) = Coleus ambonicus > Vitex negundo (alcoholic) > T. cordifolia (dichloromethane extract) > T...
  80. pmc In vitro assay for the anti-Brucella activity of medicinal plants against tetracycline-resistant Brucella melitensis
    Hossein Motamedi
    Department of Biology, Faculty of Science, Shahid Chamran University, Ahvaz, Iran
    J Zhejiang Univ Sci B 11:506-11. 2010
    ..activities of ethanolic and methanolic extracts of Salvia sclarea, Oliveria decumbens, Ferulago angulata, Vitex pseudo-negundo, Teucrium polium, Plantago ovata, Cordia myxa, and Crocus sativus were assessed...
  81. ncbi Phytochemistry and nematicidal activity of the essential oils from 8 Greek Lamiaceae aromatic plants and 13 terpene components
    Nikoletta G Ntalli
    Pesticide Science Laboratory, Faculty of Agriculture, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
    J Agric Food Chem 58:7856-63. 2010
    ..officinalis , Sideritis clandestina , Origanum dictamnus , Ocimum basilicum , Mentha pulegium , Origanum vulgare , Vitex agnus castus , and Salvia officinalis ...
  82. ncbi Larvicidal potential of medicinal plant extracts against Anopheles subpictus Grassi and Culex tritaeniorhynchus Giles (Diptera: Culicidae)
    C Kamaraj
    Unit of Bioactive Natural Products, P G and Research Department of Zoology, C Abdul Hakeem College, Melvisharam, 632 509, Vellore District, Tamil Nadu, India
    Parasitol Res 104:1163-71. 2009
    ..Leucas aspera (Willd.), Rhinacanthus nasutus KURZ., Solanum torvum Swartz and Vitex negundo Linn...
  83. ncbi Ability of certain plant extracts traditionally used to treat ciguatera fish poisoning to inhibit nitric oxide production in RAW 264.7 macrophages
    Shilpa Kumar-Roine
    Universite de Toulouse, UPS, UMR 152 Laboratoire de Pharmacochimie des Substances Naturelles et Pharmacophores Redox, 118 Rte de Narbonne, F 31062 Toulouse Cedex 9, France
    J Ethnopharmacol 123:369-77. 2009
    ..Many traditional remedies are commonly used in the Pacific against CFP. In this context, bioassay-guided screening was carried out to study NO inhibiting capacity of 28 selected plant extracts...
  84. ncbi Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay
    V K Gupta
    Department of Microbiology, Sardar Bhagwan Singh PG Institute of Biomedical Sciences and Research, Balawala, Dehradun, Uttrakhand, India
    Lett Appl Microbiol 52:33-40. 2011
    ..tuberculosis using radiometric BACTEC assay...
  85. ncbi Metal bioaccumulation in plant leaves from an industrious area and the botanical garden in Beijing
    Yan Ju Liu
    Beijing Centre for Physical and Chemical Analysis, Beijing 100089, China
    J Environ Sci (China) 17:294-300. 2005
    ..Generally, those species containing strong and moderate accumulation in both sites are considered including Vitex negundo, Broussonetia papyrifera, Ulmus pumila, and Rubia cordifolia...
  86. ncbi Comparative anti-hyperglycemic potentials of medicinal plants
    Irene M Villaseñor
    Natural Products Research Laboratory, Institute of Chemistry, University of the Philippines, Diliman, Quezon City 1101, Philippines
    J Ethnopharmacol 104:129-31. 2006
    ..Compositae), Eucalyptus tereticornis Sm. (Myrtaceae), Solanum nigrum Linn. (Solanaceae), and Vitex negundo Linn. (Verbenaceae); stems of Nopalea cochinellifera (Linn...
  87. ncbi Larvicidal efficacy of medicinal plant extracts against Anopheles stephensi and Culex quinquefasciatus (Diptera: Culicidae)
    C Kamaraj
    Unit of Bioactive Natural Products, Post Graduate and Research Department of Zoology, C Abdul Hakeem College, Melvisharam 632 509, Vellore District, Tamil Nadu, India
    Trop Biomed 27:211-9. 2010
    ..leaf ethyl acetate of Hydrocotyle javanica, methanol leaf and seed of Solanum torvum and leaf hexane extracts of Vitex negundo against the fourth instar larvae of An. stephensi and Cx. quinquefasciatus...
  88. ncbi [Interspecific association between understory species in a southern highland plantation]
    Lile Hu
    Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang, China
    Ying Yong Sheng Tai Xue Bao 16:2019-24. 2005
    ..Lespedeza davidii, Serissa serissoides, Vitex negundo var. cannabifolia...
  89. ncbi Evaluation of medicinal plants from Central Kalimantan for antimelanogenesis
    Enos Tangke Arung
    Department of Forest and Forest Products Sciences, Faculty of Agriculture, Kyushu University, 6 10 1 Hakozaki, Higashi ku, Fukuoka, 812 8581, Japan
    Nat Med (Tokyo) 63:473-80. 2009
    ..bulb), Eusideroxylon zwageri (seed), Dendrophthoe petandra (aerial root), Passiflora foetida (stem), and Vitex pinnata (root) showed DPPH radical-scavenging activity of more than 70% at 100 microg/ml. The extracts of W...
  90. pmc Casticin, a flavonoid isolated from Vitex rotundifolia, inhibits prolactin release in vivo and in vitro
    Qi Ye
    Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 31:1564-8. 2010
    to investigate the anti-hyperprolactinemia activity of casticin, a flavonoid isolated from Vitex rotundifolia, and elucidate its molecular mechanism.
  91. ncbi Total phenolic compounds, flavonoids, and radical scavenging activity of 21 selected tropical plants
    R A Mustafa
    Food Biotechnology and Functional Food Lab, Faculty of Food Science and Technology, Univ Putra Malaysia, Serdang Selangor, Malaysia
    J Food Sci 75:C28-35. 2010
    ..High content of quercetin, myricetin, and kaempferol were identified in Vitex negundo, Centella asiatica, and Sesbania grandiflora extracts, respectively...
  92. ncbi [Identification of a new subtype of blaADC produced by Acinetobacter baumannii isolated in children]
    Rui Zhen Zhao
    Department of Clinical Laboratory, Shenzhen Children s Hospital, Shenzhen, China
    Zhonghua Liu Xing Bing Xue Za Zhi 28:1009-12. 2007
    ..To investigate the genotype of blaADC which was a kind of AmpC produced by Acinetobacter baumannii (AB), isolated through the detection of 28 similar strains among children...
  93. ncbi Selection of woody species for wastewater enhancement and restoration of riparian woodlands
    M Adrover
    Department of Biology, University of Balearic Islands 07122, Palma de Mallorca, Spain
    J Environ Biol 29:357-61. 2008
    ..Nerium oleander, Tamarix africana and Vitex agnus-castus were the species with the greatest final biomass...
  94. ncbi Behavioural responses and changes in biology of rice leaffolder following treatment with a combination of bacterial toxins and botanical insecticides
    Sengottayan Senthil Nathan
    Department of Environmental Engineering, Chonbuk National University, Jeonju City, Chonbuk 561 756, Republic of Korea
    Chemosphere 64:1650-8. 2006
    Ingestion of the bacterial toxins Bacillus thuringiensis (Berliner) sub sp kurstaki, neem seed kernel extract and Vitex negundo L...
  95. ncbi Identification of methyl chloride-emitting plants and atmospheric measurements on a subtropical island
    Yoko Yokouchi
    National Institute for Environmental Studies, 16 2 Onogawa, Tsukuba, Ibaraki 305 8506, Japan
    Chemosphere 69:549-53. 2007
    ..The strongest emitters were Osmunda banksiifolia, Cibotium balometz, Angiopteris palmiformis, Vitex rotundifolia, Vitex trifolia, and Excoecaria agalloch, each with CH3Cl emission rates exceeding 1microg (gdrywt)(-..
  96. ncbi Evaluation of Myanmar medicinal plant extracts for antitrypanosomal and cytotoxic activities
    Saw Bawm
    Laboratory of Parasitology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University
    J Vet Med Sci 72:525-8. 2010
    ..6 +/- 1.5 microg/ml and the highest selectivity index of 24.4. The extracts of Brucea javanica, Vitex arborea, Eucalyptus globulus and Jatropha podagrica had also remarkable activity with IC(50) values and ..
  97. ncbi Extraction, separation and isolation of volatiles from Vitex agnus-castus L. (Verbenaceae) wild species of Sardinia, Italy, by supercritical CO2
    Bruno Marongiu
    Dipartimento di Scienze Chimiche, Universita degli Studi di Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy
    Nat Prod Res 24:569-79. 2010
    Isolation of volatile concentrates from leaves, flowers and fruits of Vitex agnus-castus L. have been obtained by supercritical extraction with carbon dioxide. The composition of the volatile concentrates has been analysed by GC/MS...
  98. pmc Essential Oil Composition and Antibacterial Studies of Vitex negundo Linn. Extracts
    S L Khokra
    University Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra 136 119, India
    Indian J Pharm Sci 70:522-6. 2008
    Essential oils from fresh leaves, flowers and dried fruits of Vitex negundo were obtained by hydrodistillation. Using Soxhlet extractor five successive extracts from dried and powdered leaves were also taken...
  99. ncbi Contrasting seasonal leaf habits of canopy trees between tropical dry-deciduous and evergreen forests in Thailand
    Atsushi Ishida
    Department of Plant Ecology, Forestry and Forest Products Research Institute, Tsukuba, Ibaraki 305 8687, Japan
    Tree Physiol 26:643-56. 2006
    ..Three canopy trees (Shorea siamensis Miq., Xylia xylocarpa (Roxb.) W. Theob. and Vitex peduncularis Wall...
  100. ncbi Casticin induces leukemic cell death through apoptosis and mitotic catastrophe
    Jia Kun Shen
    Department of Hematology, Institute of Hematology, Zhejiang University, School of Medicine, Hangzhou, Zhejiang, People s Republic of China
    Ann Hematol 88:743-52. 2009
    Casticin, a component from Vitex rotundifolia, widely used as an anti-inflammatory agent in Chinese traditional medicine, was reported to have anti-tumor activities...
  101. ncbi New diterpenes and norditerpenes from the fruits of Vitex rotundifolia
    Masateru Ono
    School of Agriculture, Kyushu Tokai University, Choyo 5435, Aso, Kumamoto 869 1404, Japan
    J Nat Prod 65:537-41. 2002
    ..and two new norlabdane-type diterpenes, vitexifolin D (4) and vitexifolin E (5), were isolated from the fruits of Vitex rotundifolia, along with a known halimane-type diterpene, vitetrifolin D (6), two known norlabdane-type diterpenes,..

Research Grants7

  1. Effect of Vitex on stress induced luteal phase defects
    Dorena Rode; Fiscal Year: 2003
    ..b>Vitex, a natural plant product, has been shown to be clinically effective in alleviating symptoms in conditions ..
  2. Molecular mechanisms of Vitex agnus-castus L. in PMS
    Zaijie Jim Wang; Fiscal Year: 2005
    b>Vitex agnus-castus L. (VAC) fruit extracts have been used since ancient times for the relief of premenstrual syndrome (PMS)...
  3. Opioid Activity / Standardization of Vitex agnus-castus
    DONNA WEBSTER; Fiscal Year: 2008
    The focus of this research is the investigation of molecular mechanisms of opioid activity in an extract of Vitex agnus-castus L. (Chasteberry), used to treat premenstrual syndrome...
  4. N-3 fatty acid & binding protein MRG on mammary tumor
    YUENIAN SHI; Fiscal Year: 2006
    ..These studies will help to identify MRG as mediator for differentiation for mammary gland and for interaction with n-3 PUPA on inhibition of mammary tumorigenesis. ..
  5. CAREER DEVELOPMENT IN WOMEN'S HEALTH RESEARCH AND GENDE*
    Ellen Freeman; Fiscal Year: 2006
    ..The BIRCWH program will track the career trajectories of Scholars and will continue to serve as a resource in terms of career counseling and research advice. [unreadable] [unreadable]..
  6. Core symptoms and profiles in premenstrual syndrome
    Ellen Freeman; Fiscal Year: 2008
    ..Further information will contribute to improved health care for women in their reproductive years. [unreadable] [unreadable] [unreadable] [unreadable]..
  7. EPIDEMIOLOGIC STUDY OF THE LATE REPRODUCTIVE YEARS
    Ellen W Freeman; Fiscal Year: 2010
    ..abstract_text> ..