soybeans

Summary

Summary: An annual legume or the seeds of this plant.

Top Publications

  1. ncbi Genome sequence of the palaeopolyploid soybean
    Jeremy Schmutz
    HudsonAlpha Genome Sequencing Center, 601 Genome Way, Huntsville, Alabama 35806, USA
    Nature 463:178-83. 2010
  2. pmc Identification of novel soybean microRNAs involved in abiotic and biotic stresses
    Franceli R Kulcheski
    Centre of Biotechnology and PPGBCM, Laboratory of Genomes and Plant Population, building 43431, Federal University of Rio Grande do Sul UFRGS, PO Box 15005, CEP 91501 970 Porto Alegre, RS, Brazil
    BMC Genomics 12:307. 2011
  3. pmc RNA-Seq Atlas of Glycine max: a guide to the soybean transcriptome
    Andrew J Severin
    Department of Agronomy, Iowa State University, Ames, IA 50011, USA
    BMC Plant Biol 10:160. 2010
  4. pmc Identification of miRNAs and their target genes in developing soybean seeds by deep sequencing
    Qing Xin Song
    State Key Laboratory of Plant Genomics, Genome Biology Center, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, PR China
    BMC Plant Biol 11:5. 2011
  5. ncbi Resequencing of 31 wild and cultivated soybean genomes identifies patterns of genetic diversity and selection
    Hon Ming Lam
    State Key Laboratory of Agrobiotechnology and School of Life Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Nat Genet 42:1053-9. 2010
  6. pmc High-throughput SNP discovery through deep resequencing of a reduced representation library to anchor and orient scaffolds in the soybean whole genome sequence
    David L Hyten
    Soybean Genomics and Improvement Laboratory, US Department of Agriculture, Agricultural Research Service, Beltsville, MD 20705, USA
    BMC Genomics 11:38. 2010
  7. ncbi An integrated transcriptome atlas of the crop model Glycine max, and its use in comparative analyses in plants
    Marc Libault
    Division of Plant Sciences, National Center for Soybean Biotechnology, C S Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA
    Plant J 63:86-99. 2010
  8. ncbi Identification of soybean microRNAs and their targets
    Baohong Zhang
    Department of Biology, East Carolina University, Greenville, NC 27858, USA
    Planta 229:161-82. 2008
  9. pmc Evaluation of putative reference genes for gene expression normalization in soybean by quantitative real-time RT-PCR
    Ruibo Hu
    Institute of Crop Science, National Key Facility of Crop Gene Resource and Genetic Improvement, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China
    BMC Mol Biol 10:93. 2009
  10. pmc Whole-genome sequencing and intensive analysis of the undomesticated soybean (Glycine soja Sieb. and Zucc.) genome
    Moon Young Kim
    Department of Plant Science and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151 921, Korea
    Proc Natl Acad Sci U S A 107:22032-7. 2010

Detail Information

Publications283 found, 100 shown here

  1. ncbi Genome sequence of the palaeopolyploid soybean
    Jeremy Schmutz
    HudsonAlpha Genome Sequencing Center, 601 Genome Way, Huntsville, Alabama 35806, USA
    Nature 463:178-83. 2010
    ..An accurate soybean genome sequence will facilitate the identification of the genetic basis of many soybean traits, and accelerate the creation of improved soybean varieties...
  2. pmc Identification of novel soybean microRNAs involved in abiotic and biotic stresses
    Franceli R Kulcheski
    Centre of Biotechnology and PPGBCM, Laboratory of Genomes and Plant Population, building 43431, Federal University of Rio Grande do Sul UFRGS, PO Box 15005, CEP 91501 970 Porto Alegre, RS, Brazil
    BMC Genomics 12:307. 2011
    ..In order to identify new miRNAs in soybean and to verify those that are possibly water deficit and rust-stress regulated, eight libraries of small RNAs were constructed and submitted to Solexa sequencing...
  3. pmc RNA-Seq Atlas of Glycine max: a guide to the soybean transcriptome
    Andrew J Severin
    Department of Agronomy, Iowa State University, Ames, IA 50011, USA
    BMC Plant Biol 10:160. 2010
    ..Patterns of gene expression provide insight into functions of genes with unknown annotation...
  4. pmc Identification of miRNAs and their target genes in developing soybean seeds by deep sequencing
    Qing Xin Song
    State Key Laboratory of Plant Genomics, Genome Biology Center, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, PR China
    BMC Plant Biol 11:5. 2011
    ....
  5. ncbi Resequencing of 31 wild and cultivated soybean genomes identifies patterns of genetic diversity and selection
    Hon Ming Lam
    State Key Laboratory of Agrobiotechnology and School of Life Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Nat Genet 42:1053-9. 2010
    We report a large-scale analysis of the patterns of genome-wide genetic variation in soybeans. We re-sequenced a total of 17 wild and 14 cultivated soybean genomes to an average of approximately ×5 depth and >90% coverage using the ..
  6. pmc High-throughput SNP discovery through deep resequencing of a reduced representation library to anchor and orient scaffolds in the soybean whole genome sequence
    David L Hyten
    Soybean Genomics and Improvement Laboratory, US Department of Agriculture, Agricultural Research Service, Beltsville, MD 20705, USA
    BMC Genomics 11:38. 2010
    ....
  7. ncbi An integrated transcriptome atlas of the crop model Glycine max, and its use in comparative analyses in plants
    Marc Libault
    Division of Plant Sciences, National Center for Soybean Biotechnology, C S Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA
    Plant J 63:86-99. 2010
    ....
  8. ncbi Identification of soybean microRNAs and their targets
    Baohong Zhang
    Department of Biology, East Carolina University, Greenville, NC 27858, USA
    Planta 229:161-82. 2008
    ..b>Soybeans were unique among plants in the frequency of occurrence of miRNA clusters...
  9. pmc Evaluation of putative reference genes for gene expression normalization in soybean by quantitative real-time RT-PCR
    Ruibo Hu
    Institute of Crop Science, National Key Facility of Crop Gene Resource and Genetic Improvement, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China
    BMC Mol Biol 10:93. 2009
    ..Thus, a systematic validation of reference genes is required to ensure proper normalization. For soybean, only a small number of validated reference genes are available to date...
  10. pmc Whole-genome sequencing and intensive analysis of the undomesticated soybean (Glycine soja Sieb. and Zucc.) genome
    Moon Young Kim
    Department of Plant Science and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151 921, Korea
    Proc Natl Acad Sci U S A 107:22032-7. 2010
    ..This suggests that soybean domestication is complicated and that more in-depth study of population genetics is needed. In any case, genome comparison of domesticated and undomesticated forms of soybean can facilitate its improvement...
  11. pmc Novel and nodulation-regulated microRNAs in soybean roots
    Senthil Subramanian
    Donald Danforth Plant Science Center, 975 N Warson Road, St Louis, MO 63132, USA
    BMC Genomics 9:160. 2008
    ..g. soybean) and rhizobia bacteria (e.g. Bradyrhizobium japonicum) results in root nodules where the majority of biological nitrogen fixation occurs. We sought to identify microRNAs (miRNAs) regulated during soybean-B. japonicum symbiosis...
  12. pmc Validation of internal control for gene expression study in soybean by quantitative real-time PCR
    Bo Jian
    School of Life Sciences, Lanzhou University, Lanzhou, Gansu 730000, PR China
    BMC Mol Biol 9:59. 2008
    ..Only a few studies on HKGs have been done in plants, and none in soybean, an economically important crop. Therefore, the present study was conducted to identify suitable HKG(s) for normalization of gene expression in soybean...
  13. pmc The soybean stem growth habit gene Dt1 is an ortholog of Arabidopsis TERMINAL FLOWER1
    Baohui Liu
    Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Harbin 150040, China
    Plant Physiol 153:198-210. 2010
    ..An association test of DNA polymorphisms with the stem growth habit among 16 cultivars suggested that a single amino acid substitution in exon 4 determines the fate of the SAM after floral induction...
  14. ncbi Physiological and molecular approaches to improve drought resistance in soybean
    Lakshmi P Manavalan
    National Center for Soybean Biotechnology and Division of Plant Sciences, University of Missouri, Columbia, MO 65211, USA
    Plant Cell Physiol 50:1260-76. 2009
    ....
  15. pmc High-density integrated linkage map based on SSR markers in soybean
    Tae Young Hwang
    National Agricultural Research Center for Hokkaido Region, Sapporo, Hokkaido 062 8555, Japan
    DNA Res 16:213-25. 2009
    ..8. Our high-density linkage map should facilitate ongoing and future genomic research such as analysis of quantitative trait loci and positional cloning in addition to marker-assisted selection in soybean breeding...
  16. pmc A soybean transcript map: gene distribution, haplotype and single-nucleotide polymorphism analysis
    Ik Young Choi
    Soybean Genomics and Improvement Laboratory, USDA, ARS, Beltsville, Maryland 20705, USA
    Genetics 176:685-96. 2007
    ....
  17. ncbi QTL mapping of ten agronomic traits on the soybean ( Glycine max L. Merr.) genetic map and their association with EST markers
    W K Zhang
    Plant Biotechnology Laboratory, Institute of Genetics and Developmental Biology, The Chinese Academy of Sciences, 100101, Beijing, China
    Theor Appl Genet 108:1131-9. 2004
    ..EST marker GmKF059a, encoding a repressor protein and mapped on group C2, accounted for about 20% of the total variation of days to flowering, plant height, lodging and nodes on the main stem, respectively...
  18. pmc Prediction of novel miRNAs and associated target genes in Glycine max
    Trupti Joshi
    Digital Biology Laboratory, Computer Science Department and Christopher S, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA
    BMC Bioinformatics 11:S14. 2010
    ..Many plant miRNAs play critical roles in nutrient homeostasis, developmental processes, abiotic stress and pathogen responses. Currently, only 70 miRNA have been identified in soybean...
  19. pmc A map-based cloning strategy employing a residual heterozygous line reveals that the GIGANTEA gene is involved in soybean maturity and flowering
    Satoshi Watanabe
    National Institute of Agrobiological Sciences, Tsukuba, Ibaraki, Japan
    Genetics 188:395-407. 2011
    ..These results indicate that GmGIa is the gene responsible for the E2 locus and that a null mutation in GmGIa may contribute to the geographic adaptation of soybean...
  20. pmc Misexpression of miR482, miR1512, and miR1515 increases soybean nodulation
    Hui Li
    Shanghai Jiaotong University, School of Agriculture and Biology, Shanghai 200240, China
    Plant Physiol 153:1759-70. 2010
    ..These results suggested that miRNAs play important roles in soybean nodule development...
  21. ncbi Functional genomics of soybean for improvement of productivity in adverse conditions
    Lam Son Phan Tran
    RIKEN Plant Science Center, Tsurumi, Yokohama 230 0045, Japan
    Funct Integr Genomics 10:447-62. 2010
    ..Soybean functional genomics, therefore, will ultimately enable us to develop new soybean varieties with improved productivity under adverse conditions by genetic engineering...
  22. pmc Genome-wide expression profiling of soybean two-component system genes in soybean root and shoot tissues under dehydration stress
    Dung Tien Le
    Signaling Pathway Research Unit, Plant Science Center, RIKEN Yokohama Institute, 1 7 22 Suehiro cho, Tsurumi, Yokohama, Japan
    DNA Res 18:17-29. 2011
    ..systematic expression analyses identified excellent dehydration-responsive candidate genes to further clarify soybean TCS functions in drought response and to enable the development of improved drought tolerance in transgenic soybeans.
  23. pmc Genome-wide survey and expression analysis of the plant-specific NAC transcription factor family in soybean during development and dehydration stress
    Dung Tien Le
    Signaling Pathway Research Unit, Plant Science Center, RIKEN Yokohama Institute, Suehiro cho, Tsurumi, Japan
    DNA Res 18:263-76. 2011
    ..Our systematic analysis has identified excellent tissue-specific and/or dehydration-responsive candidate GmNAC genes for in-depth characterization and future development of improved drought-tolerant transgenic soybeans.
  24. ncbi Long-term consumption of fermented soybean-derived Chungkookjang enhances insulinotropic action unlike soybeans in 90% pancreatectomized diabetic rats
    Dae Young Kwon
    Food Functional Research Division, Korean Food Research Institutes, Seoul, Korea
    Eur J Nutr 46:44-52. 2007
    We previously reported that Chungkookjang (CKJ), fermented unsalted soybeans, exhibited better anti-diabetic action than cooked soybeans (CSB) in vitro, but its effectiveness and mechanism have not been studied in vivo.
  25. pmc Overexpression of the soybean GmERF3 gene, an AP2/ERF type transcription factor for increased tolerances to salt, drought, and diseases in transgenic tobacco
    Gaiyun Zhang
    The National Key Facility for Crop Genetic Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China
    J Exp Bot 60:3781-96. 2009
    ..The overall results suggested that GmERF3 as an AP2/ERF transcription factor may play dual roles in response to biotic and abiotic stresses in plants...
  26. ncbi Conserved and novel miRNAs in the legume Phaseolus vulgaris in response to stress
    Catalina Arenas-Huertero
    Departamento de Biologia Molecular de Plantas, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Av Universidad 2001, Cuernavaca, Morelos, Mexico
    Plant Mol Biol 70:385-401. 2009
    ..vulgaris. We propose that the novel miRNAs present in common bean and other legumes, are involved in regulation of legume-specific processes including adaptation to diverse external cues...
  27. pmc Two coordinately regulated homologs of FLOWERING LOCUS T are involved in the control of photoperiodic flowering in soybean
    Fanjiang Kong
    Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Harbin, China
    Plant Physiol 154:1220-31. 2010
    ..Taken together, our results suggest that GmFT2a and GmFT5a coordinately control flowering and enable the adaptation of soybean to a wide range of photoperiodic environments...
  28. pmc SoyBase, the USDA-ARS soybean genetics and genomics database
    David Grant
    USDA ARS CICGRU, Department of Agronomy, Iowa State University, Ames, IA 50011, USA
    Nucleic Acids Res 38:D843-6. 2010
    ..SoyBase is the repository for controlled vocabularies for soybean growth, development and trait terms, which are also linked to the more general plant ontologies. SoyBase can be accessed at http://soybase.org...
  29. ncbi Comprehensive analysis of mitochondria in roots and hypocotyls of soybean under flooding stress using proteomics and metabolomics techniques
    Setsuko Komatsu
    National Institute of Crop Science, Tsukuba 305 8518, Japan
    J Proteome Res 10:3993-4004. 2011
    Flooding is a serious problem for soybeans because it reduces growth and grain yield. Proteomic and metabolomic techniques were used to examine whether mitochondrial function is altered in soybeans by flooding stress...
  30. pmc Characterization of the stress associated microRNAs in Glycine max by deep sequencing
    Haiyan Li
    Ministry of Education Engineering Research Center of Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun, Jilin 130118, China
    BMC Plant Biol 11:170. 2011
    ..MicroRNAs (miRNAs) have recently emerged as key regulators in gene regulation, developmental processes and stress tolerance in plants...
  31. ncbi Microsatellites are preferentially associated with nonrepetitive DNA in plant genomes
    Michele Morgante
    E I DuPont de Nemours and Co, DuPont Agriculture and Nutrition Molecular Genetics, Newark, Delaware, USA
    Nat Genet 30:194-200. 2002
    ..Contrary to previous reports suggesting a preferential mechanism for the origin of microsatellites from repetitive DNA in both animals and plants, our findings show a significant association with the low-copy fraction of plant genomes...
  32. pmc Enhanced accumulation of BiP in transgenic plants confers tolerance to water stress
    F C Alvim
    Departamento de Biologia Vegetal, , , Minas Gerais, Brazil
    Plant Physiol 126:1042-54. 2001
    ..These results suggest that overexpression of BiP in plants may prevent endogenous oxidative stress...
  33. pmc Artificial selection for determinate growth habit in soybean
    Zhixi Tian
    Department of Agronomy, Purdue University, West Lafayette, IN 47907, USA
    Proc Natl Acad Sci U S A 107:8563-8. 2010
    ....
  34. pmc Characterization of the soybean genome using EST-derived microsatellite markers
    Hiroshi Hisano
    Kazusa DNA Research Institute, 2 6 7 Kazusa Kamatari, Kisarazu, Chiba 292 0818, Japan
    DNA Res 14:271-81. 2007
    ....
  35. pmc Endogenous, tissue-specific short interfering RNAs silence the chalcone synthase gene family in glycine max seed coats
    Jigyasa H Tuteja
    Department of Crop Sciences, University of Illinois, Urbana, Illinois 61801, USA
    Plant Cell 21:3063-77. 2009
    ....
  36. ncbi Expression profiling soybean response to Pseudomonas syringae reveals new defense-related genes and rapid HR-specific downregulation of photosynthesis
    Jijun Zou
    Department of Crop Sciences, University of Illinois, Urbana 61801, USA
    Mol Plant Microbe Interact 18:1161-74. 2005
    ..Imaging analyses suggest that the decreased phiPSII was a result of physical damage to PSII reaction centers...
  37. pmc Map-based cloning of the gene associated with the soybean maturity locus E3
    Satoshi Watanabe
    National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305 8602, Japan
    Genetics 182:1251-62. 2009
    ..These results suggest that the variation in phytochrome A may contribute to the complex systems of soybean flowering response and geographic adaptation...
  38. pmc The nematode resistance allele at the rhg1 locus alters the proteome and primary metabolism of soybean roots
    Ahmed J Afzal
    Department of Molecular Biology, Southern Illinois University, Carbondale, Illinois 62901, USA
    Plant Physiol 151:1264-80. 2009
    ..3.1.45]) and two metabolites (maltose and an unknown) differed in resistant and susceptible NILs without SCN infestation and may form the basis of a new assay for the selection of resistance to SCN in soybean...
  39. pmc The effects of elevated CO2 concentration on soybean gene expression. An analysis of growing and mature leaves
    Elizabeth A Ainsworth
    United States Department of Agriculture Agricultural Research Service Photosynthesis Research Unit, Deparment of Plant Biology, University of Illinois at Urbana Champaign, Urbana, 61801, USA
    Plant Physiol 142:135-47. 2006
    ..We investigated the molecular basis for changes in leaf development at elevated [CO(2)] using soybeans (Glycine max) grown under fully open air conditions at the Soybean Free Air CO(2) Enrichment (SoyFACE) facility...
  40. ncbi A soybean β-expansin gene GmEXPB2 intrinsically involved in root system architecture responses to abiotic stresses
    Wenbing Guo
    Root Biology Centre, South China Agricultural University, Guangzhou 510642, China
    Plant J 66:541-52. 2011
    ..This finding has great agricultural potential for improving crop P uptake on both low-P and P-fertilized soils...
  41. ncbi Functional analysis of the Asian soybean rust resistance pathway mediated by Rpp2
    Ajay K Pandey
    Foreign Disease Weed Science Research Unit, United States Department of Agriculture Agricultural Research Service USDA ARS, 1301 Ditto Avenue, Ft Detrick, MD 21702, USA
    Mol Plant Microbe Interact 24:194-206. 2011
    ..Together, our results provide new insight into the signaling and biochemical pathways required for resistance against P. pachyrhizi...
  42. pmc Transcriptional programming and functional interactions within the Phytophthora sojae RXLR effector repertoire
    Qunqing Wang
    Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China
    Plant Cell 23:2064-86. 2011
    ..In support of this hypothesis, misexpression of key immediate-early and early effectors severely reduced the virulence of P. sojae transformants...
  43. ncbi Identification of microRNAs in wild soybean (Glycine soja)
    Rui Chen
    The National Key Facilities for Crop Genetic Resources and Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China
    J Integr Plant Biol 51:1071-9. 2009
    ..These results provided useful information for miRNA research in wild soybean and plants...
  44. ncbi MicroRNAs in the shoot apical meristem of soybean
    Chui E Wong
    ARC Centre of Excellence for Integrative Legume Research, Faculty of Land and Food Resources, The University of Melbourne, Parkville, Victoria, 3010, Australia
    J Exp Bot 62:2495-506. 2011
    ..Our approach identified potential key regulators and provided vital spatial information towards understanding the regulatory circuits in the SAM of soybean during shoot development...
  45. pmc Identification of soybean seed developmental stage-specific and tissue-specific miRNA targets by degradome sequencing
    Md Shamimuzzaman
    Department of Crop Sciences, University of Illinois, Urbana, IL 61801, USA
    BMC Genomics 13:310. 2012
    ..In order to dissect miRNA guided gene regulation in soybean developing seeds, we performed a transcriptome-wide experimental method using degradome sequencing to directly detect cleaved miRNA targets...
  46. pmc Genome-wide analysis of two-component systems and prediction of stress-responsive two-component system members in soybean
    Keiichi Mochida
    RIKEN Plant Science Center, 1 7 22 Suehiro cho, Tsurumi ku, Yokohama, Kanagawa 230 0045, Japan
    DNA Res 17:303-24. 2010
    ..In addition, we provide a new resource for studying the conservation and divergence among the TCSs within plant species and/or between plants and other organisms...
  47. pmc A small family of nodule specific genes from soybean
    N N Sandal
    Nucleic Acids Res 15:1507-19. 1987
    ....
  48. ncbi Legumes and soybeans: overview of their nutritional profiles and health effects
    M J Messina
    Nutrition Matters, Inc, Townsend, WA 98368, USA
    Am J Clin Nutr 70:439S-450S. 1999
    ..b>Soybeans are unique among the legumes because they are a concentrated source of isoflavones...
  49. pmc QTL mapping of domestication-related traits in soybean (Glycine max)
    Baohui Liu
    Laboratory of Plant Genetics and Evolution, Hokkaido University, Sapporo 060 8589, Japan
    Ann Bot 100:1027-38. 2007
    ..This study was conducted to characterize the genetic basis of DRTs in soybean (Glycine max) using quantitative trait locus (QTL) mapping...
  50. ncbi Molecular characterization of stress-inducible GmNAC genes in soybean
    Lam Son Phan Tran
    Division of Plant Sciences, National Center for Soybean Biotechnology, University of Missouri, Columbia, MO 65211, USA
    Mol Genet Genomics 281:647-64. 2009
    ..and development, and often results in significant losses to the yields of economically important crops such as soybeans (Glycine max L.)...
  51. ncbi Identification and expression analysis of miRNAs from nitrogen-fixing soybean nodules
    Yanwei Wang
    The State Key Laboratory of Plant Cell and Chromosome Engineering, Center of Agricultural Resources Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Shijiazhuang, Hebei, PR China
    Biochem Biophys Res Commun 378:799-803. 2009
    ..Combinatorial miRNA target prediction identified genes that are involved in multiple biological processes. The results suggest that miRNAs play critical and diverse roles in SNF, nutrient acquisition, and plant development...
  52. pmc A systematic proteomic study of seed filling in soybean. Establishment of high-resolution two-dimensional reference maps, expression profiles, and an interactive proteome database
    Martin Hajduch
    Department of Biochemistry, Life Sciences Center, University of Missouri, Columbia, Missouri 65211, USA
    Plant Physiol 137:1397-419. 2005
    ..A user-intuitive database (http://oilseedproteomics.missouri.edu) was developed to access these data for soybean and other oilseeds currently being investigated...
  53. pmc Cold-induced modulation and functional analyses of the DRE-binding transcription factor gene, GmDREB3, in soybean (Glycine max L.)
    Ming Chen
    National Key Facility for Crop Gene Resources and Genetic Improvement NKFCRI Key Laboratory of Crop Genetics and Breeding, Ministry of Agriculture, Institute of Crop Science, Chinese Academy of Agricultural Sciences CAAS, Beijing, PR China
    J Exp Bot 60:121-35. 2009
    ....
  54. pmc The composition and origins of genomic variation among individuals of the soybean reference cultivar Williams 82
    William J Haun
    Department of Agronomy and Plant Genetics, University of Minnesota, Saint Paul, Minnesota 55108, USA
    Plant Physiol 155:645-55. 2011
    ..This detailed characterization will be useful for interpreting soybean genomic data sets and highlights important considerations for research communities that are developing or utilizing a reference genome sequence...
  55. pmc Establishment of a protein reference map for soybean root hair cells
    Laurent Brechenmacher
    National Center for Soybean Biotechnology, Division of Plant Sciences, University of Missouri, Columbia, Missouri 65211, USA
    Plant Physiol 149:670-82. 2009
    ..The data presented provide useful insight into the metabolic activities of a single, differentiated plant cell type...
  56. pmc SoyDB: a knowledge database of soybean transcription factors
    Zheng Wang
    Computer Science Department, University of Missouri, Columbia, MO 65211, USA
    BMC Plant Biol 10:14. 2010
    ..In this article, we present SoyDB, a user friendly database containing comprehensive knowledge of soybean transcription factors...
  57. pmc In silico analysis of transcription factor repertoire and prediction of stress responsive transcription factors in soybean
    Keiichi Mochida
    RIKEN Plant Science Center, 1 7 22 Suehiro cho, Tsurumi ku, Yokohama, Kanagawa 230 0045, Japan
    DNA Res 16:353-69. 2009
    ..This study provides a basic framework and an important user-friendly public information resource which enables analyses of transcriptional regulation in soybean...
  58. pmc Rapid genotyping of soybean cultivars using high throughput sequencing
    Kranthi Varala
    Department of Crop Sciences, University of Illinois, Urbana Champaign, Illinois, United States of America
    PLoS ONE 6:e24811. 2011
    ..Restriction digestion of soybean genomic DNA with MseI followed by high throughput sequencing provides a rapid and reproducible method for generating SNP markers...
  59. ncbi Host-derived suppression of nematode reproductive and fitness genes decreases fecundity of Heterodera glycines Ichinohe
    Jiarui Li
    Department of Plant Pathology, Kansas State University, Manhattan, KS, 66502, USA
    Planta 232:775-85. 2010
    ..glycines infection with levels of suppression comparable to conventional resistance...
  60. pmc Supplementary feeding with fortified spreads results in higher recovery rates than with a corn/soy blend in moderately wasted children
    Danielle K Matilsky
    Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110, USA
    J Nutr 139:773-8. 2009
    ..We conclude that FS are superior supplementary foods to CSB for moderately wasted Malawian children...
  61. pmc Identification of genes associated with nitrogen-use efficiency by genome-wide transcriptional analysis of two soybean genotypes
    Qing N Hao
    Institute of Oil Crops Research, Chinese Academy of Agriculture Sciences, Wuhan 430062, China
    BMC Genomics 12:525. 2011
    ..Solexa sequencing is a new method for estimating gene expression in the transcription level. Here, the expression profiles were analyzed between two soybean varieties in N-limited conditions to identify genes related to NUE...
  62. ncbi Accumulation of functional recombinant human coagulation factor IX in transgenic soybean seeds
    Nicolau B Cunha
    Embrapa Genetic Resources and Biotechnology, Parque Estação Biológica PqEB, Av W5 Norte, Brasilia, DF 70770 917, Brazil
    Transgenic Res 20:841-55. 2011
    ..4% of normal plasma. Our results demonstrate the correct processing and stable accumulation of functional hFIX in soybean seeds stored for 6 years under room temperature conditions (22 ± 2°C)...
  63. pmc Identification of cis-acting promoter elements in cold- and dehydration-induced transcriptional pathways in Arabidopsis, rice, and soybean
    Kyonoshin Maruyama
    Biological Resources and Post harvest Division, Japan International Research Center for Agricultural Sciences, Tsukuba, Ibaraki 305 8686, Japan
    DNA Res 19:37-49. 2012
    ..In contrast, for cold-inducible promoters, the conserved hexamer sequences were diversified among these three species, suggesting the existence of diverse transcriptional regulatory pathways for cold-inducible genes among the species...
  64. pmc The soy isoflavones for reducing bone loss (SIRBL) study: a 3-y randomized controlled trial in postmenopausal women
    D Lee Alekel
    Nutrition and Wellness Research Center, Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50010 8281, USA
    Am J Clin Nutr 91:218-30. 2010
    ..Our previous study indicated that soy protein with isoflavones lessened lumbar spine bone loss in midlife women...
  65. ncbi Expression of functional recombinant human growth hormone in transgenic soybean seeds
    Nicolau B Cunha
    Embrapa Genetic Resources and Biotechnology, Parque Estação Biológica PqEB, Av W5 Norte, Brasilia, DF, 70770 917, Brazil
    Transgenic Res 20:811-26. 2011
    ..These results demonstrate that the utilisation of tissue-specific regulatory sequences is an attractive and viable option for achieving high-yield production of recombinant proteins in stable transgenic soybean seeds...
  66. ncbi Identification of glycinin and beta-conglycinin subunits that contribute to the increased protein content of high-protein soybean lines
    Hari B Krishnan
    Plant Genetics Research Unit, Agricultural Research Service, United States Department of Agriculture, Columbia, Missouri 65211, USA
    J Agric Food Chem 55:1839-45. 2007
    ....
  67. ncbi A single-repeat MYB transcription factor, GmMYB176, regulates CHS8 gene expression and affects isoflavonoid biosynthesis in soybean
    Jinxin Yi
    Southern Crop Protection and Food Research Center, Agriculture and Agri Food Canada, London, Ontario, N5V 4T3, Canada
    Plant J 62:1019-34. 2010
    ..We conclude that an R1 MYB transcription factor, GmMYB176, regulates CHS8 expression and isoflavonoid synthesis in soybean...
  68. ncbi Soybean phytophthora resistance gene Rps8 maps closely to the Rps3 region
    D Sandhu
    Department of Agronomy, Iowa State University, Ames, IA 50011 1010, USA
    J Hered 96:536-41. 2005
    ..Subsequently, bulk segregant analysis of the whole soybean genome and mapping experiments revealed that the Rps8 gene maps closely to the disease resistance gene-rich Rps3 region...
  69. ncbi Expression of FLOWERING LOCUS T from Arabidopsis thaliana induces precocious flowering in soybean irrespective of maturity group and stem growth habit
    Noriko Yamagishi
    Plant Pathology Laboratory, Faculty of Agriculture, Iwate University, Morioka, 020 8550, Japan
    Planta 233:561-8. 2011
    ..thaliana might also be conserved in soybean. A system for precocious flowering and shortening of generation time using FT-ALSV would be a useful and novel technology for efficient soybean breeding...
  70. pmc Phosphoproteomic analysis of seed maturation in Arabidopsis, rapeseed, and soybean
    Louis J Meyer
    Department of Biochemistry, Christopher S Bond Life Sciences Center, Interdisciplinary Plant Group, University of Missouri, Columbia, Missouri 65211, USA
    Plant Physiol 159:517-28. 2012
    ..This investigation shows the importance of analyzing multiple plants and plant organs to comprehensively map the complete plant phosphoproteome...
  71. pmc Whole genome co-expression analysis of soybean cytochrome P450 genes identifies nodulation-specific P450 monooxygenases
    Satish K Guttikonda
    Donald Danforth Plant Science Center, St Louis, MO 63132, USA
    BMC Plant Biol 10:243. 2010
    ..This approach is based on the assumption that genes that have similar expression patterns across a set of conditions may have a functional relationship...
  72. ncbi QTL mapping for photoperiod insensitivity of a Japanese soybean landrace Sakamotowase
    Baohui Liu
    the Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Harbin, China
    J Hered 101:251-6. 2010
    The insensitivity of flowering to long daylength is an important characteristic which soybeans have used to adapt to environments at higher latitude...
  73. pmc Complete transcriptome of the soybean root hair cell, a single-cell model, and its alteration in response to Bradyrhizobium japonicum infection
    Marc Libault
    Division of Plant Sciences, National Center for Soybean Biotechnology, CS Bond Life Sciences Center, University of Missouri, Columbia, Missouri 65211, USA
    Plant Physiol 152:541-52. 2010
    ..Our analysis also highlighted changes in the expression pattern of some homeologous and tandemly duplicated soybean genes, supporting their rapid specialization...
  74. ncbi Molecular, anatomical and physiological properties of a genetically modified soybean line transformed with rd29A:AtDREB1A for the improvement of drought tolerance
    A M Polizel
    Departamento de Genetica, Universidade Estadual de Londrina, Londrina, PR, Brasil
    Genet Mol Res 10:3641-56. 2011
    ..Overexpression of AtDREB1A may contribute to a decrease in leaf thickness; however, a thicker abaxial epidermis was observed. Overexpression of AtDREB1A in soybean appears to enhance drought tolerance...
  75. ncbi Effects of co-inoculation with arbuscular mycorrhizal fungi and rhizobia on soybean growth as related to root architecture and availability of N and P
    Xiurong Wang
    Key Laboratory of Soil and Plant Nutrition in South China, Ministry of Agriculture Root Biology Center, South China Agricultural University, Guangzhou 510642, China
    Mycorrhiza 21:173-81. 2011
    ....
  76. pmc An integrative approach to genomic introgression mapping
    Andrew J Severin
    Department of Agronomy, Iowa State University, Ames, Iowa 50011, USA
    Plant Physiol 154:3-12. 2010
    ..We conclude that the comparative RNA-Seq approach can be optimized with sufficient sampling and by utilizing a post hoc correction accounting for gene density variation that controls for false discoveries...
  77. ncbi Functional characterization of a UDP-glucose:flavonoid 3-O-glucosyltransferase from the seed coat of black soybean (Glycine max (L.) Merr.)
    Nik Kovinich
    Bioproducts and Bioprocesses, Research Branch, Agriculture and Agri Food Canada, Ottawa, ON, Canada K1A 0C6
    Phytochemistry 71:1253-63. 2010
    ..RT-PCR confirmed the co-expression of one of these genes (Glyma08g07130) with UGT78K1 in the seed coat of black soybean, suggesting possible functional redundancies in anthocyanin biosynthesis in this tissue...
  78. ncbi Different domains of Phytophthora sojae effector Avr4/6 are recognized by soybean resistance genes Rps4 and Rps6
    Daolong Dou
    Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University Blacksburg 24061, USA
    Mol Plant Microbe Interact 23:425-35. 2010
    ..Compared with alleles from avirulent races, alleles of Avr4/6 from virulent races possess nucleotide substitutions in the 5' untranslated region of the gene but not in the protein-coding region...
  79. pmc The development of an efficient multipurpose bean pod mottle virus viral vector set for foreign gene expression and RNA silencing
    Chunquan Zhang
    Department of Plant Pathology, Iowa State University, Ames, Iowa 50011, USA
    Plant Physiol 153:52-65. 2010
    ..These results demonstrate the utility of this BPMV vector set for a wide range of applications in soybean and common bean, and they have implications for improvement of other plant virus-based vector systems...
  80. ncbi Complete inventory of soybean NAC transcription factors: sequence conservation and expression analysis uncover their distinct roles in stress response
    Guilherme L Pinheiro
    Departamento de Bioquimica e Biologia Molecular, Laboratório de Biologia Molecular de Plantas, BIOAGRO, Universidade Federal de Vicosa, 36570 000, Vicosa, Minas Gerais, Brazil
    Gene 444:10-23. 2009
    ..Our results indicate that the described soybean NACs are functionally non-redundant transcription factors involved in response to abiotic stresses and in cell death events in soybean...
  81. pmc The Phytophthora sojae avirulence locus Avr3c encodes a multi-copy RXLR effector with sequence polymorphisms among pathogen strains
    Suomeng Dong
    Agriculture and Agri Food Canada, London, Ontario, Canada
    PLoS ONE 4:e5556. 2009
    ..The results illustrate the importance of segmental duplications and RXLR effector evolution in the control of race-cultivar compatibility in the P. sojae and soybean interaction...
  82. pmc Distinct changes in soybean xylem sap proteome in response to pathogenic and symbiotic microbe interactions
    Senthil Subramanian
    Donald Danforth Plant Science Center, St Louis, MO, 63132, USA
    BMC Plant Biol 9:119. 2009
    ..We analyzed the xylem sap proteome of soybean seedlings in response to pathogenic and symbiotic interactions to identify systemic signaling proteins and other differentially expressed proteins...
  83. ncbi Soy intake and urinary sex hormone levels in preschool Japanese children
    Keiko Wada
    Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, Gifu, Japan
    Am J Epidemiol 173:998-1003. 2011
    ..Total energy intake was not associated with any sex steroids in boys or girls. These results suggest that soy intake might affect the secretion or metabolism of sex steroids in childhood and that the effects might differ by sex...
  84. pmc Patterning of virus-infected Glycine max seed coat is associated with suppression of endogenous silencing of chalcone synthase genes
    Mineo Senda
    Gene Research Center, Hirosaki University, Hirosaki, 036 8561, Japan
    Plant Cell 16:807-18. 2004
    ..These results demonstrate that naturally occurring PTGS plays a key role in expression of a distinctive phenotype in plants and present a simple clear example of the elucidation of the molecular mechanism for viral symptom induction...
  85. ncbi Genetic diversity in domesticated soybean (Glycine max) and its wild progenitor (Glycine soja) for simple sequence repeat and single-nucleotide polymorphism loci
    Ying Hui Li
    The National Key Facility for Crop Gene Resources and Genetic Improvement NFCRI Key Lab of Germplasm Utilization MOA, Institute of Crop Science, Chinese Academy of Agricultural Sciences, 100081 Beijing, China
    New Phytol 188:242-53. 2010
    ..soja and G. max represent distinct germplasm pools. Limited evidence of admixture was discovered between these two species. Overall, our analyses are consistent with the origin of G. max from regions along the Yellow River of China...
  86. ncbi Soybeans as bioreactors for biopharmaceuticals and industrial proteins
    G R Vianna
    Laboratório de Transferência e Expressão de Genes, EMBRAPA Recursos Geneticos e Biotecnologia, Parque Estação Biológica, Brasilia, DF, Brasil
    Genet Mol Res 10:1733-52. 2011
    ..This is an important step in the development of genetically engineered products that are inexpensive and safe for medicinal, food and other uses...
  87. pmc Genome-scale identification of soybean BURP domain-containing genes and their expression under stress treatments
    Hongliang Xu
    College of Life Sciences, Capital Normal University, Beijing, 100048, China
    BMC Plant Biol 10:197. 2010
    ..To date, the molecular function of the BURP domain is still unknown, and no systematic analysis and expression profiling of the gene family in soybean (Glycine max) has been reported...
  88. pmc Mutant alleles of FAD2-1A and FAD2-1B combine to produce soybeans with the high oleic acid seed oil trait
    Anh Tung Pham
    University of Missouri, Division of Plant Sciences, 110 Waters Hall, Columbia, MO 65211, USA
    BMC Plant Biol 10:195. 2010
    ..The objective of this work was to create the high oleic acid trait in soybeans by identifying and combining mutations in two delta-twelve fatty acid desaturase genes, FAD2-1A and FAD2-1B.
  89. pmc A nematode demographics assay in transgenic roots reveals no significant impacts of the Rhg1 locus LRR-Kinase on soybean cyst nematode resistance
    Sara Melito
    Department of Plant Pathology, University of Wisconsin Madison, Madison, WI 53706, USA
    BMC Plant Biol 10:104. 2010
    ..Generation of fertile transgenic soybean lines is difficult but methods have been published that test SCN resistance in transgenic roots generated with Agrobacterium rhizogenes...
  90. ncbi Mapping quantitative trait loci for seed size traits in soybean (Glycine max L. Merr.)
    Yu Xu
    Section on Statistical Genomics, State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Agriculture, Nanjing Agricultural University, 1 Weigang Road, Nanjing, China
    Theor Appl Genet 122:581-94. 2011
    ..Most M-QTL were clustered in eight chromosomal regions. Our results provide a good foundation for fine mapping, cloning and designed molecular breeding of favorable genes related to soybean seed size traits...
  91. ncbi Genetic analysis of genes controlling natural variation of seed coat and flower colors in soybean
    Kiwoung Yang
    Bio Evaluation Center, Korea Research Institute of Bioscience and Biotechnology, Cheongwon, Chungbuk 363 883, Republic of Korea
    J Hered 101:757-68. 2010
    ....
  92. pmc Engineering vitamin E content: from Arabidopsis mutant to soy oil
    Alison L Van Eenennaam
    Monsanto Company, Calgene Campus, Davis, California 95616, USA
    Plant Cell 15:3007-19. 2003
    ..These findings demonstrate the utility of a gene identified in Arabidopsis to alter the tocopherol composition of commercial seed oils, a result with both nutritional and food quality implications...
  93. pmc The ER luminal binding protein (BiP) mediates an increase in drought tolerance in soybean and delays drought-induced leaf senescence in soybean and tobacco
    Maria Anete S Valente
    Departamento de Bioquimica e Biologia Molecular, BIOAGRO, Universidade Federal de Vicosa, Avenida PH Rolfs s n, 36571 000 Vicosa, MG, Brazil
    J Exp Bot 60:533-46. 2009
    ..The delay in leaf senescence by BiP overexpression might relate to the absence of the response to drought...
  94. ncbi The use of microRNAs as reference genes for quantitative polymerase chain reaction in soybean
    Franceli Rodrigues Kulcheski
    Centre of Biotechnology, Laboratory of Genomes and Plant Population, Federal University of Rio Grande do Sul UFRGS, CEP 91501 970, Porto Alegre, RS, Brazil
    Anal Biochem 406:185-92. 2010
    ..Furthermore, these miRNAs genes were more stable than the most commonly protein-coding genes used in soybean gene expression studies involving RT-qPCR...
  95. ncbi Plant NAC-type transcription factor proteins contain a NARD domain for repression of transcriptional activation
    Yu Jun Hao
    Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
    Planta 232:1033-43. 2010
    ..It is hypothesized that the interactions between the repression domain NARD and the carboxy-terminal activation domain may finally determine the ability of NAC family proteins to regulate downstream gene expressions...
  96. pmc A Phytophthora sojae G-protein alpha subunit is involved in chemotaxis to soybean isoflavones
    Chenlei Hua
    Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China
    Eukaryot Cell 7:2133-40. 2008
    ....
  97. pmc Molecular and chromosomal evidence for allopolyploidy in soybean
    Navdeep Gill
    Department of Agronomy, Purdue University, West Lafayette, Indiana 47907, USA
    Plant Physiol 151:1167-74. 2009
    ..Together, these observations provide direct evidence, at molecular and chromosomal levels, in support of the hypothesis that the soybean genome has experienced a recent allopolyploidization event...
  98. pmc Complementary genetic and genomic approaches help characterize the linkage group I seed protein QTL in soybean
    Yung Tsi Bolon
    United States Department of Agriculture Agricultural Research Service, Plant Research Unit, St Paul, MN 55108, USA
    BMC Plant Biol 10:41. 2010
    ..A quantitative trait locus (QTL) on Linkage Group I (LG I) of soybean (Glycine max (L.) Merrill) has a striking effect on seed protein content...
  99. pmc Infection and genotype remodel the entire soybean transcriptome
    Lecong Zhou
    Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA
    BMC Genomics 10:49. 2009
    ....
  100. pmc RXLR-mediated entry of Phytophthora sojae effector Avr1b into soybean cells does not require pathogen-encoded machinery
    Daolong Dou
    Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
    Plant Cell 20:1930-47. 2008
    ..Mutational analysis of the RXLR motif shows that the required residues are very similar in the motifs of Plasmodium and Phytophthora. Thus, the machinery of the hosts (soybean and human) targeted by the effectors may be very ancient...
  101. ncbi Identification of a Brazil-nut allergen in transgenic soybeans
    J A Nordlee
    Department of Food Science and Technology, University of Nebraska, Lincoln, 68583 0919, USA
    N Engl J Med 334:688-92. 1996
    BACKGROUND. The nutritional quality of soybeans (Glycine max) is compromised by a relative deficiency of methionine in the protein fraction of the seeds...

Research Grants65

  1. Xenoestrogen regulation of Leydig cells
    BENSON TOKUNBO AKINGBEMI; Fiscal Year: 2010
    ..each year are exposed to the phytoestrogens genistein and daidzen, which are the predominant isoflavones in soybeans. Several reports in the literature have shown that exposure of rodents and non human primates to soy isoflavones ..
  2. Anti-Inflammatory mechanisms of soybean-derived Bowman-Birk protease inhibitor
    Abdolmohamad Rostami; Fiscal Year: 2012
    ..provided by applicant): Bowman-Birk Inhibitor (BBI) is an orally active serine protease inhibitor derived from soybeans. BBI concentrate (BBIC) is an extract of soybeans enriched in BBI...
  3. A Novel Therapy for Staphylococcal Enterotoxin B Poisoning
    Kenneth J Piller; Fiscal Year: 2010
    ..Phase I studies, we demonstrated our ability to express a non-toxic form of SEB at high levels in transgenic soybeans. Oral immunizations using soy milk formulations made from transgenic seeds expressing mutant SEB could elicit ..
  4. Modulation of antitumor immunity by dietary soy and its isoflavone constituents
    Gregory B Lesinski; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Soybeans and the foods derived from them are a rich source of bioactive phytochemicals that promote health...
  5. BOTANICAL CENTER FOR AGE-RELATED DISEASES
    Connie M Weaver; Fiscal Year: 2010
    ..Specific Aim 3 is to study metabolism of isoflavones in soybeans and kudzu. We have developed the ability to prepare C-14 and C-13 labeled plant tissue culture...
  6. Serum IGFs--Effects of a Soy Intervention in Humans
    Johanna Lampe; Fiscal Year: 2002
    ..Studies in animals and one report in humans suggest that isoflavones, bioactive agents in soybeans, can also alter IGF levels in directions that may protect against cancer...
  7. ANALYSIS AND PHYSIOLOGY OF ISOFLAVONES IN SOYBEANS
    Kenneth Setchell; Fiscal Year: 1993
    ..We will also refine existing mass spectrometric methods to permit the determination of isoflavones in tissues. The results of these studies will permit the most appropriate design of future dietary intervention studies using soy protein...
  8. Soy Immunotherapy for Patients with Peanut Anaphylaxis
    ARVIL BURKS; Fiscal Year: 2004
    ..Based on a novel idea that the storage proteins in soybeans would share enough amino acid homology with the respective peanut allergens to down regulate peanut-specific T ..
  9. RED CLOVER PHYTOESTROGENS EFFECTS ON ATHEROSCLEROSIS
    James Goodrich; Fiscal Year: 1999
    ..Plant estrogens, also termed isoflavones or phytoestrogens found in legumes such as soybeans and red clover are a natural alternative which may have greater acceptance from the public...
  10. EFFECT OF SOYBEANS ON BONE AND THE REPRODUCTIVE TRACT
    JANICE BAHR; Fiscal Year: 2002
    ..An alternative approach is intake of foods rich in phytoestrogens - natural plant estrogens such as soybeans. The hypothesis is that soy protein protects against postmenopausal bone loss by slowing resorption and enhancing ..
  11. ISOFLAVONE-RICH PASTA--CLINICAL AND COMMERCIAL POTENTIAL
    RICHARDUS ROSS; Fiscal Year: 2000
    ..in the US whereas they are less problematic in countries where plant-based diets, especially those containing soybeans are a staple...
  12. SOYBEANS AND CALCIUM METABOLISM IN POSTMENOPAUSAL WOMEN
    ELAINE LIPSCOMB; Fiscal Year: 1999
    ..b>Soybeans and their products are the principal source of the isoflavones, genistein and daidzein...
  13. Phytoestrogens as an alternative treatment for MS
    Larry Sherman; Fiscal Year: 2006
    ..The therapeutic potential of phytoestrogens in MS, has yet to be studied. Isoflavones derived from soybeans are a rich source of phytoestrogens...
  14. TRANSGENIC SOYBEAN FORMULA TO ENHANCE RESECTION-INDUCED INTESTINAL ADAPTATION
    BRAD WAYNE WARNER; Fiscal Year: 2013
    ..Washington University School of Medicine will develop and do animal testing of a soy-milk formula produced from soybeans genetically engineered to synthesize EGF...
  15. Analysis of Phenolic Phytochemical by ESI-MS
    Jennifer Brodbelt; Fiscal Year: 2003
    ..and characterization of phenolic phytochemicals and their metabolites in urine, tissue and food, especially soybeans, kale and citrus fruit...
  16. Novel therapy for treating Multiple Sclerosis
    KENNETH PILLER; Fiscal Year: 2009
    ..proposed: Milestone #1: A novel fusion protein for treating Multiple Sclerosis will be expressed in transgenic soybeans. In milestone #1, we will establish soybean lines and produce soybean seeds in bulk quantities that can be used ..
  17. DIETARY SOY EFFECTS ON MARKERS OF PROSTATE CANCER
    W Lee; Fiscal Year: 2000
    ..b>Soybeans and related legumes contain large quantities of plant estrogens known as isoflavones...
  18. DIETARY SOYBEAN COMPONENTS AFFECT ON PROSTATE CANCER PRO
    Jin Rong Zhou; Fiscal Year: 2001
    The long-term objective of this application is to test the hypothesis that soybeans bioactive components inhibit the growth and metastasis of prostate cancer (CaP)...
  19. MECHANISM OF INDUCTION OF OLFACTORY TUMORS BY ALACHLOR
    Mary Beth Genter; Fiscal Year: 2002
    ..chloracetanilide herbicides are used world-wide in the production of important food crops such as corn and soybeans, providing significant potential for environmental contamination and human exposure...
  20. Chemoprevention of Oral Cancer with BBIC
    Frank Meyskens; Fiscal Year: 2007
    ..proposal is to determine whether Bowman-Birk Inhibitor (BBI) Concentrate (C), a protease inhibitor extracted from soybeans, can cause regression of oral leukoplakia and whether certain candidate intermediate marker endpoints can predict ..
  21. A Novel Therapy for Staphyloccocal Enterotoxin B poisoning
    KENNETH PILLER; Fiscal Year: 2007
    ..vaccine against a non-toxic form of Staphylococcus enterotoxin B (SEB) by expressing this immunogen in transgenic soybeans. Completion of such studies will be significant since SEB has been identified as a potential agent of ..
  22. GENISTEIN AS MODULATOR OF ANTIOXIDANT PROTEIN EXPRESSION
    Shiu Ming Kuo; Fiscal Year: 2002
    ..Among them, genistein (Gn) is found especially at high concentration in soybeans, an important element of Oriental diet...
  23. QUANTITATION & BIOAVAILABILITY OF SOYFOOD ISOFLAVONES
    Patricia Murphy; Fiscal Year: 1992
    ..on the distribution of the isoflavones will be examined by manufacturing soy foods from specific varieties of soybeans. The bioavailability of the soy isoflavones will be assessed by administering single doses of isoflavones in ..
  24. Efficacy of soybean-based vaccines using a model antigen
    KENNETH PILLER; Fiscal Year: 2007
    ..address some of the most important challenges that face this technology for developing edible subunit vaccines in soybeans which could be applied to the formulation of novel human gastrointestinal vaccines...
  25. Soy Isoflavones on NO Production in Postmenopausal Women
    William Wong; Fiscal Year: 2003
    ..which have chemical structures similar to estradiol but possess anti-cancer properties, are found in abundance in soybeans. Our preliminary data showed that diastolic blood pressure was reduced by 12% and urinary nitrate excretion was ..
  26. DEVELOPMENT AND EVALUATION OF A SOYFOOD QUESTIONNAIRE
    Johanna Lampe; Fiscal Year: 1999
    DESCRIPTION: (Applicant's Description) In recent years, numerous studies have suggested that the consumption of soybeans and soybean-containing foods may contribute to the lower rates of breast, colon, and prostate cancer in Asia as ..
  27. GENETICS OF HOST-SPECIFIC INFECTION BY RHIZOBIA
    Gary Stacey; Fiscal Year: 1990
    ..Lastly, we will undertake studies to determine the biochemical functions of the genes identified. The goal of this research is an understanding of the mechanism of host recognition in the infection of soybeans by B. japonicum.
  28. An edible adjuvant expressed in transgenic soybeans
    KENNETH BOST; Fiscal Year: 2005
    ..coil heat labile toxin (LT), and its expression in soybeans. A non-toxic form of this bacterial protein, which has potent adjuvant activity, will be expressed in soybeans, ..
  29. Phytochemicals, ER-Stress and Prostate Cancer
    Karen Auborn; Fiscal Year: 2007
    Our overall goal is to determine mechanisms whereby genistein, the major isoflavone in soybeans, prevents growth and induces apoptosis of prostate cancer cells...
  30. PROTEASE INHIBITORS AND INFLAMMATION
    Jeffrey Ware; Fiscal Year: 1999
    ..In Phase I of the grant work, it was established that an extract of soybeans containing the protease inhibitor BBIC could be used as an anti-inflammatory agent in an in vivo model of ..
  31. Nutritional Risk Factors for Type 2 Diabetes in the Multiethnic Cohort
    Gertraud Maskarinec; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  32. Soy Consumption and Breast Tissue Proliferation
    Gertraud Maskarinec; Fiscal Year: 2006
    ....
  33. Effects of Soy on Estrogens in Breast Fluid and Urine
    Gertraud Maskarinec; Fiscal Year: 2010
    ..The NAF approach is the only way to learn more about the beneficial and adverse effects of soy directly in the female breast without applying invasive procedures to women without breast disease or surgery. ..
  34. NESTED CASE CONTROL STUDY OF MAMMOGRAPHIC DENSITY
    Gertraud Maskarinec; Fiscal Year: 2002
    ....
  35. Inflammatory Markers in a 2-Year Soy Intervention among Premenopausal Women
    Gertraud Maskarinec; Fiscal Year: 2008
    ..The statistical analysis will apply general linear models to compare the levels of inflammatory markers by soy intake, while taking into account the repeated measurement design. [unreadable] [unreadable] [unreadable] [unreadable]..
  36. Breast Density, IGF-I, & Prolactin, in Four Populations
    Gertraud Maskarinec; Fiscal Year: 2004
    ..The statistical analysis will include mixed models to explore the relation between hormone levels and breast density while controlling for confounders and for clustering by study location. ..
  37. ANTIVIRAL & ANTIFIBROTIC LIVER THERAPY OF HCV+ DRINKERS
    Charles Lieber; Fiscal Year: 2005
    ..is the supplemention with an anti-fibrotic agent, namely polyenylphosphatidylcholine (PPC) extracted from soybeans, or placebo, administered for 3 years (concomitantly with the antiviral treatment and thereafter)...
  38. MECHANISM AND ROLE OF MICROSOMAL ETHANOL OXIDATION
    Charles Lieber; Fiscal Year: 2001
    ..Such information is aimed at elucidating key aspects of alcohol mediated pathology in a way which may eventually affect alcohol related medical complications, their prevention and treatment. ..
  39. Liquid Chromatography Mass Spectrometry system
    Adrian Franke; Fiscal Year: 2005
    ..abstract_text> ..
  40. Synergistic Nutraceutical Effects of DLPC and SAMe
    Charles Lieber; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  41. Antiviral/Antifibrotic Liver Therapy of Hepatitis C positive Alcohol Drinkers
    Charles Lieber; Fiscal Year: 2007
    ..with placebo or polyenylphosphatidylcholine (PPC), an innocuous antifibrotic and antioxidant agent extracted from soybeans, administered for 3 years, starting with the antiviral treatment...
  42. Liver Fibrosis, Inflammation & Oxidative Stress Markers
    Charles Lieber; Fiscal Year: 2006
    ..abstract_text> ..
  43. DLPC Treatment of Alcoholic and Non-Alcoholic Fibrosis
    Charles Lieber; Fiscal Year: 2006
    ..We previously observed that polyenylphosphatidylcholine (PPC) extracted from soybeans fully prevents alcohol-induced cirrhosis in non-human primates...
  44. Alcohol: Direct and Indirect Effects in Drug Metabolism
    THOMAS BADGER; Fiscal Year: 2008
    ..abstract_text> ..
  45. Center for Nutrient-Gene Interaction in Cancer Preventi*
    Stephen Barnes; Fiscal Year: 2008
    ..In addition to the main projects, the Center will organize a competitive Pilot Project/Developmental program for the evaluation of new ideas and methods pertinent to the overall development of the Center. ..
  46. Mammographic Density and Soy Isoflavones
    Lee Jane W Lu; Fiscal Year: 2010
    ..The study may lead to a novel, non-invasive and economical approach to breast cancer prevention. ..
  47. AMINO ACID CONJUGATION OF BILE ACIDS
    Stephen Barnes; Fiscal Year: 2006
    ..abstract_text> ..
  48. Soy Isoflavone Metabolite Equol--Formation and Fate
    Kenneth Setchell; Fiscal Year: 2008
    ..abstract_text> ..
  49. Mammalian Lactoferrin Receptors: Structure and Function
    Bo Lonnerdal; Fiscal Year: 2007
    ..Overall, our understanding of the physiological significance of Lf and its receptor will be increased. ..
  50. Chemopreventive Actions of Equol Enantiomers
    Kenneth Setchell; Fiscal Year: 2007
    ..These studies are relevant to humans given the ammended health claim for soy and cancer risk-reduction currently being reviewed by the FDA. ..
  51. 9.4 Tesla Fourier Transform Mass Spectrometer
    Stephen Barnes; Fiscal Year: 2002
    ..Overall, the FT-MS instrument will sustain the high quality of biomedical research that is a hallmark of UAB. ..
  52. Soy Isoflavone Distribution in Biological Fluids as Markers of Prostate Exposure
    MINDY KURZER; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  53. A sensitive triple quadrupole mass spectrometer
    Stephen Barnes; Fiscal Year: 2004
    ..It is anticipated that a commercial nanospray interface for use in nanoLC-MS analysis will be available by the fall of 2003. ..
  54. Assessing Spouses' Support of the Diabetic Diet
    J Brown; Fiscal Year: 2003
    ..Confirmation of the hypotheses will mean the CDSA can be used to assess married or cohabiting type 2 diabetic's degree of success in adjusting to the diabetic diet and identify those needing more couple-based dietary instruction. ..
  55. HOST GENES AND COLONIC BACTERIA--PROBING FOR INHERITANCE
    Johanna Lampe; Fiscal Year: 2002
    ..If we can establish that the equol-producer phenotype is an inherited trait, we can then work to identify the associated genotype and determine more effectively whether this is a biomarker of breast cancer risk. ..
  56. Inflammatory Biomarkers and Colorectal Cancer Risk
    Gong Yang; Fiscal Year: 2010
    ..Overall, this study will contribute significantly to the understanding of the role of inflammation in the etiology of CRC and to the development of new strategies for the assessment of CRC risk. ..
  57. Workshop on BioIron in Thalassemia, Sickle Cell Disease and Hemochromatosis
    Elizabeth Theil; Fiscal Year: 2004
    ..Fuller understanding of iron homeostasis in Thalassemia, Sickle Cell Disease and Hemochromatosis and improved disease management strategies can be expected. ..
  58. Environmental Impact on Perinatal Lung Metabolism
    Oliver Fiehn; Fiscal Year: 2009
    ..abstract_text> ..
  59. Membrane Interactions of C2 Domains
    David Cafiso; Fiscal Year: 2009
    ..A better understanding of these events may also lead to the development of new approaches to control cell growth and cancer. ..
  60. Ferritin and Iron Nutrition in Health and Disease
    Elizabeth Theil; Fiscal Year: 2005
    ..The results will clarify mechanisms of ferritin iron uptake and characterize molecular genetic differences in iron uptake for improving dietary iron sources in health and disease. ..
  61. Effects of Amino Acid Therapy on Hot Flashes in Postmenopausal Women
    Thomas Guttuso; Fiscal Year: 2007
    ..The applicant will also attend two didactic training seminars in complementary & alternative medicine at The Osher Institute at Harvard Medical School and at the Duke Center for Integrative Medicine. ..
  62. GLUTATHIONE TRANSFERASES IN HUMANS: DIETARY INFLUENCES
    Johanna Lampe; Fiscal Year: 2006
    ..abstract_text> ..
  63. Female Hormones and Vision
    Alvin Eisner; Fiscal Year: 2006
    ..abstract_text> ..