fabaceae

Summary

Summary: The large family of plants characterized by pods. Some are edible and some cause LATHYRISM or FAVISM and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various lectins like PHYTOHEMAGGLUTININS from PHASEOLUS. Many of them harbor NITROGEN FIXATION bacteria on their roots.

Top Publications

  1. pmc Legumes: importance and constraints to greater use
    Peter H Graham
    Department of Soil, Water, and Climate, Agricultural Research Service, Plant Science Research Unit, University of Minnesota, St Paul, Minnesota 55108, USA
    Plant Physiol 131:872-7. 2003
  2. ncbi The rules of engagement in the legume-rhizobial symbiosis
    Giles E D Oldroyd
    John Innes Center, Norwich Research Park, Norwich NR4 7UH, United Kingdom
    Annu Rev Genet 45:119-44. 2011
  3. pmc A consensus genetic map of cowpea [Vigna unguiculata (L) Walp.] and synteny based on EST-derived SNPs
    Wellington Muchero
    Departments of Nematology and Botany and Plant Sciences, University of California, Riverside, CA 92521, USA
    Proc Natl Acad Sci U S A 106:18159-64. 2009
  4. ncbi Establishing nitrogen-fixing symbiosis with legumes: how many rhizobium recipes?
    Catherine Masson-Boivin
    Laboratoire des Interactions Plantes Micro organismes LIPM, UMR CNRS INRA 2594 441, BP 52627, 31326 Castanet Tolosan Cedex, France
    Trends Microbiol 17:458-66. 2009
  5. ncbi Metabolic changes of rhizobia in legume nodules
    Juergen Prell
    School of Biological Sciences, University of Reading, UK, RG6 6AJ
    Trends Microbiol 14:161-8. 2006
  6. ncbi Legume-nodulating betaproteobacteria: diversity, host range, and future prospects
    Prasad Gyaneshwar
    Department of Biological Sciences, University of Wisconsin Milwaukee, Milwaukee, WI, USA
    Mol Plant Microbe Interact 24:1276-88. 2011
  7. ncbi A plant regulator controlling development of symbiotic root nodules
    L Schauser
    Department of Molecular and Structural Biology, University of Aarhus, Denmark
    Nature 402:191-5. 1999
  8. ncbi Symbiotic implications of type III protein secretion machinery in Rhizobium
    V Viprey
    Laboratoire de Biologie Moleculaire des Plantes Superieures, Universite de Geneve, Geneva, Switzerland
    Mol Microbiol 28:1381-9. 1998
  9. ncbi Evolving ideas of legume evolution and diversity: a taxonomic perspective on the occurrence of nodulation
    Janet I Sprent
    Division of Applied and Environmental Biology, College of Life Sciences, University of Dundee, Dundee, UK
    New Phytol 174:11-25. 2007
  10. ncbi Lifestyle alternatives for rhizobia: mutualism, parasitism, and forgoing symbiosis
    R Ford Denison
    Department of Agronomy and Range Science, University of California at Davis, 1 Shields Avenue, Davis, CA 95616, USA
    FEMS Microbiol Lett 237:187-93. 2004

Detail Information

Publications357 found, 100 shown here

  1. pmc Legumes: importance and constraints to greater use
    Peter H Graham
    Department of Soil, Water, and Climate, Agricultural Research Service, Plant Science Research Unit, University of Minnesota, St Paul, Minnesota 55108, USA
    Plant Physiol 131:872-7. 2003
  2. ncbi The rules of engagement in the legume-rhizobial symbiosis
    Giles E D Oldroyd
    John Innes Center, Norwich Research Park, Norwich NR4 7UH, United Kingdom
    Annu Rev Genet 45:119-44. 2011
    ....
  3. pmc A consensus genetic map of cowpea [Vigna unguiculata (L) Walp.] and synteny based on EST-derived SNPs
    Wellington Muchero
    Departments of Nematology and Botany and Plant Sciences, University of California, Riverside, CA 92521, USA
    Proc Natl Acad Sci U S A 106:18159-64. 2009
    ..These results support evolutionary closeness between cowpea and soybean and identify regions for synteny-based functional genomics studies in legumes...
  4. ncbi Establishing nitrogen-fixing symbiosis with legumes: how many rhizobium recipes?
    Catherine Masson-Boivin
    Laboratoire des Interactions Plantes Micro organismes LIPM, UMR CNRS INRA 2594 441, BP 52627, 31326 Castanet Tolosan Cedex, France
    Trends Microbiol 17:458-66. 2009
    ..In this article, we review the cumulative evidence from recent genomic and genetic analyses pointing toward an unexpected variety of mechanisms that lead to symbiosis with legumes...
  5. ncbi Metabolic changes of rhizobia in legume nodules
    Juergen Prell
    School of Biological Sciences, University of Reading, UK, RG6 6AJ
    Trends Microbiol 14:161-8. 2006
    ..This review aims to summarize the metabolic plasticity of rhizobia and the importance of amino acid cycling...
  6. ncbi Legume-nodulating betaproteobacteria: diversity, host range, and future prospects
    Prasad Gyaneshwar
    Department of Biological Sciences, University of Wisconsin Milwaukee, Milwaukee, WI, USA
    Mol Plant Microbe Interact 24:1276-88. 2011
    Rhizobia form specialized nodules on the roots of legumes (family Fabaceae) and fix nitrogen in exchange for carbon from the host plant...
  7. ncbi A plant regulator controlling development of symbiotic root nodules
    L Schauser
    Department of Molecular and Structural Biology, University of Aarhus, Denmark
    Nature 402:191-5. 1999
    ..NIN protein has regional similarity to transcription factors, and the predicted DNA-binding/dimerization domain identifies and typifies a consensus motif conserved in plant proteins with a function in nitrogen-controlled development...
  8. ncbi Symbiotic implications of type III protein secretion machinery in Rhizobium
    V Viprey
    Laboratoire de Biologie Moleculaire des Plantes Superieures, Universite de Geneve, Geneva, Switzerland
    Mol Microbiol 28:1381-9. 1998
    ....
  9. ncbi Evolving ideas of legume evolution and diversity: a taxonomic perspective on the occurrence of nodulation
    Janet I Sprent
    Division of Applied and Environmental Biology, College of Life Sciences, University of Dundee, Dundee, UK
    New Phytol 174:11-25. 2007
    ..Nodule morphology and structure are host-determined, but the effectiveness of nitrogen fixation is largely controlled by the bacterial symbionts, which vary greatly in genotypic and phenotypic characters...
  10. ncbi Lifestyle alternatives for rhizobia: mutualism, parasitism, and forgoing symbiosis
    R Ford Denison
    Department of Agronomy and Range Science, University of California at Davis, 1 Shields Avenue, Davis, CA 95616, USA
    FEMS Microbiol Lett 237:187-93. 2004
    ..Legume sanctions against nodules that fix little or no nitrogen favor more mutualistic strains, but parasitic strains that use plant resources only for their own reproduction may do well when they share nodules with mutualistic strains...
  11. ncbi Burkholderia phymatum is a highly effective nitrogen-fixing symbiont of Mimosa spp. and fixes nitrogen ex planta
    Geoffrey N Elliott
    School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK
    New Phytol 173:168-80. 2007
    ..B. phymatum is therefore an effective Mimosa symbiont with a broad host range, and is the first reported beta-rhizobial strain to fix nitrogen in free-living culture...
  12. pmc Nutrient sharing between symbionts
    James White
    School of Biological Sciences, University of Reading, Whiteknights Reading RG6 6AJ, United Kingdom
    Plant Physiol 144:604-14. 2007
  13. ncbi Identification of medicinal plants in the family Fabaceae using a potential DNA barcode ITS2
    Ting Gao
    Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, 151 Malianwa North Road, Haidian District, Beijing 100193, PR China
    J Ethnopharmacol 130:116-21. 2010
    To test whether the ITS2 region is an effective marker for use in authenticating of the family Fabaceae which contains many important medicinal plants.
  14. ncbi Root nodule bacteria isolated from South African Lotononis bainesii, L. listii and L. solitudinis are species of Methylobacterium that are unable to utilize methanol
    Julie Kaye Ardley
    Centre for Rhizobium Studies, School of Biological Sciences and Biotechnology, Murdoch University, Perth, WA, Australia
    Arch Microbiol 191:311-8. 2009
    ..While methylotrophy appears to contribute to the effectiveness of the Crotalaria/M. nodulans symbiosis, our results indicate that the ability to utilize methanol is not a factor in the Lotononis/Methylobacterium symbiosis...
  15. pmc Identification and comparative analysis of drought-associated microRNAs in two cowpea genotypes
    Blanca E Barrera-Figueroa
    Department of Botany and Plant Sciences, University of California, Riverside, CA 92521, USA
    BMC Plant Biol 11:127. 2011
    ..In addition, it is not understood how miRNAs might contribute to different capacities of drought tolerance in different cowpea genotypes...
  16. pmc Genetic diversity and geographic differentiation in endangered Ammopiptanthus (Leguminosae) populations in desert regions of northwest China as revealed by ISSR analysis
    Xue Jun Ge
    South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, P R China
    Ann Bot 95:843-51. 2005
    ..The desert legume genus Ammopiptanthus comprises two currently endangered species, A. mongolicus and A. nanus. Genetic variability and genetic differentiation between the two species and within each species were examined...
  17. pmc De novo sequencing and analysis of root transcriptome using 454 pyrosequencing to discover putative genes associated with drought tolerance in Ammopiptanthus mongolicus
    Yijun Zhou
    College of Life and Environmental Sciences, Minzu University of China, Beijing, 100081, China
    BMC Genomics 13:266. 2012
    ..mongolicus. Thus, high throughput transcriptome sequencing from A. mongolicus root is helpful to generate a large amount of transcript sequences for gene discovery and molecular marker development...
  18. pmc Saturation of an intra-gene pool linkage map: towards a unified consensus linkage map for fine mapping and synteny analysis in common bean
    Carlos H Galeano
    Department of Microbial and Molecular Systems, Centre of Microbial and Plant Genetics, KU Leuven, Heverlee, Belgium
    PLoS ONE 6:e28135. 2011
    ..Our results, combined with synteny relationships provide tools to increase marker density in selected genomic regions to identify closely linked polymorphic markers for indirect selection, fine mapping or for positional cloning...
  19. ncbi The impact of landscape disturbance on spatial genetic structure in the Guanacaste tree, Enterolobium cyclocarpum (Fabaceae)
    Eva Gonzales
    Department of Ecology, Evolution and Natural Resources, Rutgers University, New Brunswick, NJ, USA
    J Hered 101:133-43. 2010
    ....
  20. pmc A SNP and SSR based genetic map of asparagus bean (Vigna. unguiculata ssp. sesquipedialis) and comparison with the broader species
    Pei Xu
    Institute of Vegetables, Zhejiang Academy of Agricultural Sciences, Hangzhou, People s Republic of China
    PLoS ONE 6:e15952. 2011
    ..japonica was also established. This work provides the basis for mapping and functional analysis of genes/QTLs of particular interest in asparagus bean, as well as for comparative genomics study of cowpea at the subspecies level...
  21. ncbi Mechanism of Trypanosoma cruzi death induced by Cratylia mollis seed lectin
    M P Fernandes
    Departamento de Patologia Clinica, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, Brazil
    J Bioenerg Biomembr 42:69-78. 2010
    ....
  22. pmc A comprehensive transcriptome assembly of Pigeonpea (Cajanus cajan L.) using sanger and second-generation sequencing platforms
    Himabindu Kudapa
    International Crops Research Institute for the Semi Arid Tropics, Patancheru 502324, India
    Mol Plant 5:1020-8. 2012
    ..16 polymorphism information content (PIC) value. In summary, the CcTA v2 transcript assembly and ISR markers will serve as a useful resource to accelerate genetic research and breeding applications in pigeonpea...
  23. ncbi Elevated CO2 reduces losses of plant diversity caused by nitrogen deposition
    Peter B Reich
    Department of Forest Resources, University of Minnesota, 1530 Cleveland Avenue North, St Paul, MN 55108, USA
    Science 326:1399-402. 2009
    ..This resulted from multiple effects of CO2 and N on plant traits and soil resources that altered competitive interactions among species. Elevated CO2 thus ameliorated the negative effects of N enrichment on species richness...
  24. pmc Genomes of the symbiotic nitrogen-fixing bacteria of legumes
    Allyson M MacLean
    Department of Biology, Center for Environmental Genomics, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    Plant Physiol 144:615-22. 2007
  25. ncbi Investigations of Rhizobium biofilm formation
    Nancy A Fujishige
    Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, USA
    FEMS Microbiol Ecol 56:195-206. 2006
    ..To investigate whether there was a symbiotic phenotype, we tested one of the Fla- mutants on two different S. meliloti hosts, alfalfa and white sweetclover, and found that nodule formation was significantly delayed on the latter...
  26. ncbi QTL for seed iron and zinc concentration and content in a Mesoamerican common bean (Phaseolus vulgaris L.) population
    Matthew W Blair
    CIAT Biotechnology Unit and Bean Project, International Center for Tropical Agriculture, A A 6713, Cali, Colombia, South America
    Theor Appl Genet 121:1059-70. 2010
    ..The discovery of an important new locus for seed iron and zinc concentrations may facilitate crop improvement and biofortification using the high-mineral genotype especially within the Mesoamerican genepool...
  27. ncbi Antinociceptive activity of Amazonian Copaiba oils
    Niele Matos Gomes
    Departamento de Farmacologia Basica e Clinica, ICB, Universidade Federal do Rio de Janeiro, RJ, Brasil
    J Ethnopharmacol 109:486-92. 2007
    ..antinociceptive activity of two Amazonian Copaiba oils (Copaifera multijuga Hayne and Copaifera reticulata Ducke, Fabaceae) administered by oral route using peripheral (acetic acid-induced abdominal writhing and formalin), spinal (tail ..
  28. ncbi Phylogenetic analyses of symbiotic nodulation genes support vertical and lateral gene co-transfer within the Bradyrhizobium genus
    Lionel Moulin
    Laboratoire des Symbioses Tropicales et Méditerranéennes, IRD INRA CIRAD ENSAM, 34398 Montpellier, France
    Mol Phylogenet Evol 30:720-32. 2004
    ..These data indicated that the spread and maintenance of nodulation genes within the Bradyrhizobium genus occurred through vertical transmission, although lateral gene transfer also played a significant role...
  29. pmc Cytogenetic map of common bean (Phaseolus vulgaris L.)
    Artur Fonsêca
    Laboratory of Plant Cytogenetics, Department of Botany, Federal University of Pernambuco, Recife, PE, 50670 420, Brazil
    Chromosome Res 18:487-502. 2010
    ..Altogether, the results indicate that around half of the common bean genome is heterochromatic and that genes and repetitive sequences are intermingled in the euchromatin and heterochromatin of the species...
  30. ncbi Syntenic relationships among legumes revealed using a gene-based genetic linkage map of common bean (Phaseolus vulgaris L.)
    Melody McConnell
    Genomics and Bioinformatics Program, North Dakota State University, Fargo, ND 58105, USA
    Theor Appl Genet 121:1103-16. 2010
    ..While only short blocks of synteny were observed with At, large-scale macrosyntenic blocks were observed with Mt and Lj. By using Mt and Lj as bridging species, the syntenic relationship between the common bean and peanut was inferred...
  31. pmc Genic SNP markers and legume synteny reveal candidate genes underlying QTL for Macrophomina phaseolina resistance and maturity in cowpea [Vigna unguiculata (L) Walp.]
    Wellington Muchero
    Nematology Dep, University of California Riverside, 3401 Watkins Drive, Riverside, CA 92521, USA
    BMC Genomics 12:8. 2011
    ..phaseolina and the genetic mapping of putative resistance loci on a cowpea genetic map comprised of gene-derived single nucleotide polymorphisms (SNPs) and amplified fragment length polymorphisms (AFLPs)...
  32. ncbi Causes of plant diversification in the Cape biodiversity hotspot of South Africa
    Jan Schnitzler
    Division of Biology, Imperial College London, Silwood Park Campus, Ascot, Berkshire SL5 7PY, UK
    Syst Biol 60:343-57. 2011
    ....
  33. ncbi Nodulation of legumes by members of the beta-subclass of Proteobacteria
    L Moulin
    Laboratoire des Symbioses Tropicales et Méditerranéennes, IRD INRA CIRAD ENSAM Baillarguet, Montpellier, France
    Nature 411:948-50. 2001
    ..Here we report the identification of proteobacteria from the beta-subclass that nodulate legumes. This finding shows that the ability to establish a symbiosis with legumes is more widespread in bacteria than anticipated to date...
  34. pmc Functional adaptation of a plant receptor-kinase paved the way for the evolution of intracellular root symbioses with bacteria
    Katharina Markmann
    Genetics, Faculty of Biology, Ludwig Maximilians Universitat, Munich, Germany
    PLoS Biol 6:e68. 2008
    ..Our data support the idea that SYMRK sequence evolution was involved in the recruitment of a pre-existing signalling network from AM, paving the way for the evolution of intracellular root symbioses with nitrogen-fixing bacteria...
  35. pmc Protein mobilization in germinating mung bean seeds involves vacuolar sorting receptors and multivesicular bodies
    Junqi Wang
    Department of Biology and Molecular Biotechnology Program, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
    Plant Physiol 143:1628-39. 2007
    ....
  36. pmc Complete plastid genome sequence of the chickpea (Cicer arietinum) and the phylogenetic distribution of rps12 and clpP intron losses among legumes (Leguminosae)
    Robert K Jansen
    Section of Integrative Biology and Institute of Cellular and Molecular Biology, Biological Laboratories 404, University of Texas, Austin, TX 78712, USA
    Mol Phylogenet Evol 48:1204-17. 2008
    ..The availability of the complete chickpea plastid genome sequence also provides valuable information on intergenic spacer regions among legumes and endogenous regulatory sequences for plastid genetic engineering...
  37. ncbi Reproductive isolation between divergent races of pea aphids on two hosts. II. Selection against migrants and hybrids in the parental environments
    S Via
    Department of Biology, University of Maryland, College Park 20742, USA
    Evolution 54:1626-37. 2000
    ..Although this variation suggests that a generalized pea aphid could evolve, such generalists are not seen in field collections of these populations...
  38. ncbi Agrobacterium rhizogenes-transformed roots of Medicago truncatula for the study of nitrogen-fixing and endomycorrhizal symbiotic associations
    A Boisson-Dernier
    , INRA-CNRS UMR215, Castanet-Tolosan, France
    Mol Plant Microbe Interact 14:695-700. 2001
    ..Our results suggest that M. truncatula hairy roots represent a particularly attractive system with which to study endosymbiotic associations in transgenically modified roots...
  39. pmc Genome-wide annotation of remorins, a plant-specific protein family: evolutionary and functional perspectives
    Sylvain Raffaele
    Laboratoire de Biogenese Membranaire, Centre National de la Recherche Scientifique Université Victor Segalen Bordeaux 2, 33076 Bordeaux Cedex, France
    Plant Physiol 145:593-600. 2007
  40. pmc Floral development in legumes
    Shirley C Tucker
    Department of Ecology, Environment, and Marine Biology, University of California, Santa Barbara, California 93106 9610, USA
    Plant Physiol 131:911-26. 2003
  41. ncbi Classification of rhizobia based on nodC and nifH gene analysis reveals a close phylogenetic relationship among Phaseolus vulgaris symbionts
    G Laguerre
    Laboratoire de Microbiologie des Sols, Centre de Microbiologie du Sol et de L Environnement, INRA, 17 rue Sully, BP 86510, F 21065 Dijon Cedex, France
    Microbiology 147:981-93. 2001
    ..The results support the view that lateral genetic transfer across rhizobial species and, in some instances, across Rhizobium and Sinorhizobium genera plays a role in diversification and in structuring the natural populations of rhizobia...
  42. ncbi Nonlegume Parasponia andersonii deploys a broad rhizobium host range strategy resulting in largely variable symbiotic effectiveness
    Rik H M Op den Camp
    Department of Plant Sciences, Wageningen University, Wageningen, The Netherlands
    Mol Plant Microbe Interact 25:954-63. 2012
    ..Therefore, we argue that the Parasponia-rhizobium symbiosis is a delicate balance between mutual benefits and parasitic colonization...
  43. ncbi Controlling the reproductive fate of rhizobia: how universal are legume sanctions?
    Ryoko Oono
    Ecology Evolution and Behavior, University of Minnesota, Saint Paul, MN 55108, USA
    New Phytol 183:967-79. 2009
    ..Both the importance of sanctions to hosts and possible physiological mechanisms for sanctions may depend on whether bacteroids are potentially reproductive...
  44. pmc Foods and food groups associated with the incidence of colorectal polyps: the Adventist Health Study
    Yessenia M Tantamango
    Department of Epidemiology and Biostatistics, School of Public Health, Loma Linda University, Loma Linda, California 92350, USA
    Nutr Cancer 63:565-72. 2011
    ..These associations showed a dose-response effect. High frequency of consumption of cooked green vegetables, dried fruit, legumes, and brown rice was associated with a decreased risk of colorectal polyps...
  45. ncbi Total polyphenols, antioxidant and antiproliferative activities of different extracts in mungbean seeds and sprouts
    Dong Kwan Kim
    Jeonnam Agricultural Research and Extension Services, Naju, 520 715, South Korea
    Plant Foods Hum Nutr 67:71-5. 2012
    ..During sprouting of mungbean, all the studied components significantly increased. In conclusion, the extracts of sprouts are more effective than from seeds and could be a potential source of antioxidants linked with health benefits...
  46. ncbi Burkholderia tuberum sp. nov. and Burkholderia phymatum sp. nov., nodulate the roots of tropical legumes
    Peter Vandamme
    Laboratorium voor Microbiologie, Faculteit Wetenschappen, Universiteit Gent, Gent, Belgium
    Syst Appl Microbiol 25:507-12. 2002
    ..The remaining two isolates were identified as novel Burkholderia species for which we propose the names Burkholderia tuberum sp. nov. and Burkholderia phymatum sp. nov. The type strains are LMG 21444T and LMG 21445T, respectively...
  47. ncbi Rhizobial adaptation to hosts, a new facet in the legume root-nodule symbiosis
    Marion Koch
    Institute of Microbiology, ETH, Zurich, Switzerland
    Mol Plant Microbe Interact 23:784-90. 2010
    ..japonicum. The respective mutant had a symbiotic defect on siratro rather than on soybean or cowpea. This result demonstrates the value of the applied approach and corroborates the host-specific adaptation concept...
  48. ncbi Phenetic relationships among different races of Striga gesnerioides (Willd.) Vatke from West Africa
    Christopher J Botanga
    Department of Biology, University of Virginia, Glimmer Hall, Charlottesville, VA 22904, USA
    Genome 49:1351-65. 2006
    ..gesnerioides. Our data suggest that both geographic isolation and host-driven selection are critical factors defining race formation in S. gesnerioides in West Africa...
  49. ncbi Changes in oxygen and carbon dioxide environment alter gene expression of cowpea bruchids
    Yong Hun Chi
    Department of Entomology, Texas A and M University, College Station, TX 77843, USA
    J Insect Physiol 57:220-30. 2011
    ..Gene expression profiles suggested that insects compensate for lack of oxygen by coordinately reducing energy demand, shifting to anaerobic metabolism, and strengthening cellular structure and muscular contraction...
  50. ncbi Symbiotic use of pathogenic strategies: rhizobial protein secretion systems
    William J Deakin
    LBMPS, University of Geneva, 30, quai Ernest Ansermet Sciences III, CH 1211 Geneve 4, Geneva, Switzerland
    Nat Rev Microbiol 7:312-20. 2009
    ..One group of proteins secreted by rhizobia have homologues in bacterial pathogens and may have been co-opted by rhizobia for symbiotic purposes...
  51. ncbi Ent-2'-epi-Orobanchol and its acetate, as germination stimulants for Striga gesnerioides seeds isolated from cowpea and red clover
    Kotomi Ueno
    Graduate School of Agricultural Science, Kobe University, Rokkodai, Nada, Kobe 657 8501, Japan
    J Agric Food Chem 59:10485-90. 2011
    ..Identity of the stimulants produced by cowpea to those produced by red clover (Trifolium pratense) was confirmed...
  52. ncbi Bacteroid development in legume nodules: evolution of mutual benefit or of sacrificial victims?
    Attila Kereszt
    Hungarian Academy of Sciences, Szeged, Hungary
    Mol Plant Microbe Interact 24:1300-9. 2011
    ..This article provides an overview on the bacteroid and symbiosome development including the terminal differentiation of bacteria in IRLC legumes as well as the bacterial and plant genes and proteins participating in these processes...
  53. ncbi 8S globulin of mungbean [Vigna radiata (L.) Wilczek]: cloning and characterization of its cDNA isoforms, expression in Escherichia coli, purification, and crystallization of the major recombinant 8S isoform
    Amy Emiliana N Bernardo
    Institute of Plant Breeding, College of Agriculture, University of the Philippines Los Banos, College, Laguna Philippines 4031
    J Agric Food Chem 52:2552-60. 2004
    ..The recombinant 8Salpha, but not the native form, was successfully crystallized producing rhombohedral crystals...
  54. ncbi Multilocus sequence analysis of the genus Bradyrhizobium
    Raul Rivas
    Laboratory of Microbiology WE10, Faculty of Sciences, Ghent University, K L Ledeganckstraat 35, B 9000 Ghent, Belgium
    Syst Appl Microbiol 32:101-10. 2009
    ..The majority of the new isolates from the three host species was identified as Bradyrhizobium canariense. Four strains from L. albus from León, Spain, formed a separate group close to Bradyrhizobium japonicum...
  55. pmc Glutathione and homoglutathione synthetases of legume nodules. Cloning, expression, and subcellular localization
    J F Moran
    Departamento de Nutrición Vegetal, Estacion Experimental de Aula Dei, Consejo Superior de Investigaciones Cientificas, Apdo 202, 50080 Zaragoza, Spain
    Plant Physiol 124:1381-92. 2000
    ..Overall, our results provide further evidence that thiol synthesis is critical for nodule functioning...
  56. pmc Enterolobium contortisiliquum trypsin inhibitor (EcTI), a plant proteinase inhibitor, decreases in vitro cell adhesion and invasion by inhibition of Src protein-focal adhesion kinase (FAK) signaling pathways
    Cláudia Alessandra Andrade de Paula
    Department of Biochemistry and Molecular Biology, Universidade Federal de Sao Paulo Escola Paulista de Medicina, Sao Paulo, Brazil
    J Biol Chem 287:170-82. 2012
    ..Together, these results indicate that EcTI inhibits the invasion of gastric cancer cells through alterations in integrin-dependent cell signaling pathways...
  57. ncbi Diversity and relationships of bradyrhizobia from legumes native to eastern North America
    Matthew A Parker
    Department of Biological Sciences, State University of New York, Binghamton, NY 13902, USA
    Can J Microbiol 52:1148-57. 2006
    ..elkanii lineage to the B. japonicum group) and suggest that transfers have also occurred among separate subgroups of the B. elkanii lineage...
  58. ncbi Antihyperglycaemic effect and acute toxicity of Securigera Securidaca L. seed extracts in mice
    H Hosseinzadeh
    Pharmaceutical Research Center, School of Pharmacy, Mashhad University of Medical Sciences, P O Box 91775 1365, Mashhad, I R Iran
    Phytother Res 16:745-7. 2002
    ..The results indicate that S. securidaca seed extracts significantly reduce blood glucose in alloxan-induced diabetic mice by a mechanism different from that of sulfonylurea agents...
  59. ncbi Antidiabetic activity of Mung bean extracts in diabetic KK-Ay mice
    Yang Yao
    Institute of Crop Science, Chinese Academy of Agricultural Sciences, No 80 South Xueyuan Road, Haidian District, Beijing, People s Republic of China
    J Agric Food Chem 56:8869-73. 2008
    ..These results suggest that MBS and MBSC exert an antidiabetic effect in type 2 diabetic mice...
  60. ncbi [Effect of Spatholobus suberectus on the bone marrow cells and related cytokines of mice]
    Dong Hui Chen
    Sichuan University, Chengdu 610064, China
    Zhongguo Zhong Yao Za Zhi 29:352-5. 2004
    ..To study the effect of Spatholobus suberectus on proliferation and the hematonic mechanism...
  61. ncbi Immunomodulatory response of Cramoll 1,4 lectin on experimental lymphocytes
    Cristiane Moutinho Lagos de Melo
    Centro de Pesquisas Aggeu Magalhães CPqAM FIOCRUZ, Pernambuco, Brazil
    Phytother Res 24:1631-6. 2010
    ..Therefore, Cramoll 1,4 can be considered a lectin with immunomodulatory activity...
  62. ncbi Effect of Brazilian copaiba oils on Leishmania amazonensis
    Adriana O Santos
    Programa de Pós Graduação em Microbiologia, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid s n, 86051 990 Londrina PR, Brazil
    J Ethnopharmacol 120:204-8. 2008
    ..The use of copaiba oils to treat leishmaniasis is cited in several ethnopharmacological studies. Nevertheless, the potential antileishmania of copaiba oils had not been studied...
  63. ncbi Gene-for-gene resistance in Striga-cowpea associations
    Jianxiong Li
    Department of Biology, University of Virginia, Charlottesville, VA 22903, USA
    Science 325:1094. 2009
    ..Our findings indicate that a gene-for-gene resistance mechanism is operating in these unique plant-plant associations...
  64. pmc The genome of Rhizobium leguminosarum has recognizable core and accessory components
    J Peter W Young
    Department of Biology, University of York, York, UK
    Genome Biol 7:R34. 2006
    ..We have sequenced the genome of R. leguminosarum biovar viciae strain 3841...
  65. ncbi Glutathione half-cell reduction potential: a universal stress marker and modulator of programmed cell death?
    Ilse Kranner
    Seed Conservation Department, Royal Botanic Gardens, Kew, Wakehurst Place, West Sussex RH17 6TN, UK
    Free Radic Biol Med 40:2155-65. 2006
    ..E(GSSG/2GSH) is therefore a universal marker of plant cell viability and allows us to predict whether a seed will live, germinate, and produce a new plant, or if it will die...
  66. ncbi Evaluating the nodulation status of leguminous species from the Amazonian forest of Brazil
    Sergio M de Faria
    Embrapa Agrobiologia Km 47 antiga estrada Rio São Paulo, Cep 23890 000 Seropédica RJ, Brazil
    J Exp Bot 61:3119-27. 2010
    ..Twelve non-nodulating leguminous species were also observed for the first time. The results are discussed based on the systematics of the Leguminosae family and the influence of available nutrients to the legume-bacteria symbiosis...
  67. ncbi Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins
    Aaron G Poth
    Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, Australia
    ACS Chem Biol 6:345-55. 2011
    ..Clitoria ternatea (Butterfly pea) is a member of plant family Fabaceae and through its usage in traditional medicine to aid childbirth bears similarity to Oldenlandia affinis, from ..
  68. ncbi Evaluation of hepatoprotective activity of legumes
    S J Wu
    Department of Health and Nutrition, Chia-Nan University of Pharmacy and Science, Tainan, Taiwan, ROC
    Phytomedicine 8:213-9. 2001
    ..In addition to these results, the extract of mung bean acted as a potential hepatoprotective agent in dietary supply...
  69. ncbi Healing activity induced by Cramoll 1,4 lectin in healthy and immunocompromised mice
    Cristiane Moutinho Lagos de Melo
    Centro de Pesquisas Aggeu Magalhães CPqAM FIOCRUZ, Pernambuco, Brazil crismout
    Int J Pharm 408:113-9. 2011
    ..Results showed that Cramoll 1,4 lectin was effective in the repair of experimental lesions in mice and can be used as a future cicatricial compound...
  70. ncbi Fiber intake, constipation, and overweight among adolescents living in Sao Paulo City
    Erica Bloes de Carvalho
    Postgraduate Course of Nutrition, Federal University of Sao Paulo, Sao Paulo, Brazil
    Nutrition 22:744-9. 2006
    ..This study evaluated the dietary fiber intake of adolescents in the metropolitan area of Sao Paulo city and any association between low dietary fiber intake with constipation and overweight...
  71. ncbi Separating multiple, short-term, deleterious effects of saline solutions on the growth of cowpea seedlings
    Peter M Kopittke
    The University of Queensland, School of Land, Crop and Food Sciences, St Lucia, QLD 4072, Australia
    New Phytol 189:1110-21. 2011
    ..A multiple regression model related root growth to osmolarity and {I(z)}₀° (R²=0.924), allowing the quantification of their effects...
  72. ncbi Assessment of antioxidant activity of extracts from unique Greek varieties of Leguminosae plants using in vitro assays
    C Spanou
    Department of Biochemistry and Biotechnology, University of Thessaly, Larissa, Greece
    Anticancer Res 27:3403-10. 2007
    ....
  73. ncbi Microbiological and chemical changes during the fermentation of African locust bean (Parkia biglobosa) to produce afitin, iru and sonru, three traditional condiments produced in Benin
    P Azokpota
    Département de Nutrition et Sciences Alimentaires, Faculté des Sciences Agronomiques, Université d Abomey Calavi, 01 BP 526 Cotonou, Benin
    Int J Food Microbiol 107:304-9. 2006
    ..Due to their long fermentation time, iru and sonru are very soft products as they are preferred by some consumers whereas afitin is preferred with cotyledons having less soft texture...
  74. ncbi Early developmental and stress responsive ESTs from mungbean, Vigna radiata (L.) Wilczek, seedlings
    Li Ru Chen
    Institute of Bioinformatics and Structural Biology and Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan, ROC
    Plant Cell Rep 27:535-52. 2008
    ....
  75. ncbi Mapping of gene-specific markers on the genetic map of chickpea (Cicer arietinum L.)
    T Pfaff
    Plant Molecular Biology, Biocenter, University of Frankfurt, Marie Curie Str 9, Germany
    Mol Genet Genomics 269:243-51. 2003
    ..reticulatum. Forty-seven gene-specific markers were integrated into an existing map based on STMS, AFLP, DAF and other anonymous markers. The potential of this approach is discussed...
  76. pmc Polyploidy did not predate the evolution of nodulation in all legumes
    Steven B Cannon
    United States Department of Agriculture Agricultural Research Service, Corn Insects and Crop Genomics Research Unit, Iowa State University, Ames, Iowa, United States of America
    PLoS ONE 5:e11630. 2010
    ..g., mimosas, acacias)--which diverged from the papilionoid legumes around 58 million years ago, soon after the origin of the legumes...
  77. ncbi Positive regulation of the Hrp type III secretion system in Pseudomonas syringae pv. phaseolicola
    Inmaculada Ortiz-Martín
    Instituto de Hortofruticultura Subtropical y Mediterranea, Universidad de Málaga Consejo Superior de Inverstigaciones Cientificas, Depto Biología cellular, Genética y Fisiología, Spain
    Mol Plant Microbe Interact 23:665-81. 2010
    ....
  78. pmc Legume evolution: where do nodules and mycorrhizas fit in?
    Janet I Sprent
    Division of Applied and Environmental Biology, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom
    Plant Physiol 144:575-81. 2007
  79. pmc Analysis of the role of the type III effector inventory of Pseudomonas syringae pv. phaseolicola 1448a in interaction with the plant
    Adela Zumaquero
    Instituto de Hortofruticultura Subtropical y Mediterranea, Universidad de Malaga, Consejo Superior de Investigaciones Científicas IHSM UMA CSIC, Departamento Biologia Celular, Genética y Fisiología, Campus de Teatinos, Malaga, Spain
    J Bacteriol 192:4474-88. 2010
    ....
  80. ncbi The Nod factor-independent symbiotic signaling pathway: development of Agrobacterium rhizogenes-mediated transformation for the legume Aeschynomene indica
    Katia Bonaldi
    IRD, Laboratoire des Symbioses Tropicales et Méditerranéennes, UMR IRD SupAgro INRA UM2 CIRAD, F 34398 Montpellier, France
    Mol Plant Microbe Interact 23:1537-44. 2010
    ..indica and that Agrobacterium rhizogenes-mediated root transformation of Aeschynomene spp. will be an invaluable tool for determining the molecular basis of the NF-independent symbiosis...
  81. ncbi Identification of Fabaceae plants using the DNA barcode matK
    Ting Gao
    Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, PR China
    Planta Med 77:92-4. 2011
    In this study, we tested the applicability of the core DNA barcode MATK for identifying species within the Fabaceae family...
  82. pmc Conservation of plasmid-encoded traits among bean-nodulating Rhizobium species
    Susana Brom
    Programa de Genetica Molecular de Plasmidos Bacterianos, Centro de Investigacion Sobre Fijacion de Nitrogeno, UNAM, Cuernavaca, Morelos, Mexico
    Appl Environ Microbiol 68:2555-61. 2002
    ..In contrast, strains belonging to other bean-nodulating species seem to have acquired only the pSym plasmid from R. etli...
  83. ncbi Antioxidant and free-radical scavenging activity of constituents of the leaves of Tachigalia paniculata
    Giuseppina Cioffi
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo, 84084 Fisciano SA, Italy
    J Nat Prod 65:1526-9. 2002
    ..Compounds 1, 2, and 6 showed activity in the TEAC test, compounds 5-7 and 10 were moderately active in the autoxidation assay, while compounds 1 and 2 were the most potent of the isolates in the xanthine oxidase test...
  84. ncbi Evolutionary rates analysis of Leguminosae implicates a rapid diversification of lineages during the tertiary
    Matt Lavin
    Department of Plant Sciences, Montana State University, Bozeman, Montana 59717, USA
    Syst Biol 54:575-94. 2005
    ..This explains why groups such as the millettioids are amenable to species-level phylogenetic analysis with these loci, whereas other legume groups are not...
  85. ncbi Early manganese-toxicity response in Vigna unguiculata L.--a proteomic and transcriptomic study
    Hendrik Führs
    Institute for Plant Nutrition, Faculty of Natural Sciences, Leibniz University Hannover, Herrenhaeuser Strasse 2, Hannover, Germany
    Proteomics 8:149-59. 2008
    ..In conclusion, a coordinated interplay of apoplastic and symplastic reactions seems to be important during the Mn-stress response in cowpea...
  86. pmc Within-plant signaling by volatiles leads to induction and priming of an indirect plant defense in nature
    Martin Heil
    Fachbereich 9, Allgemeine Botanik Pflanzenökologie, Universitat Duisburg Essen, Universitätstrasse 5, D 45117 Essen, Germany
    Proc Natl Acad Sci U S A 104:5467-72. 2007
    ....
  87. pmc Genome dissection of traits related to domestication in azuki bean (Vigna angularis) and comparison with other warm-season legumes
    Takehisa Isemura
    National Institute of Agrobiological Sciences, Kannondai 2 1 2, Tsukuba 305 8602, Ibaraki, Japan
    Ann Bot 100:1053-71. 2007
    ....
  88. pmc Protective mechanism of the Mexican bean weevil against high levels of alpha-amylase inhibitor in the common bean
    M Ishimoto
    Department of Biology 0116, University of California, San Diego, La Jolla 92093 0116, USA
    Plant Physiol 111:393-401. 1996
    ..chinensis. Alpha AI-2 and alpha AI-Pa, on the other hand, do inhibit the alpha-amylase of Z. subfasciatus, suggesting that they are good candidates for genetic engineering to achieve resistance to Z. subfasciatus...
  89. ncbi Pollen dispersal of tropical trees (Dinizia excelsa: Fabaceae) by native insects and African honeybees in pristine and fragmented Amazonian rainforest
    Christopher W Dick
    Biological Dynamics of Forest Fragments Project, Instituto Nacional de Pesquisas da Amazonia, c p 478, Manaus, AM 69011 970, Brazil
    Mol Ecol 12:753-64. 2003
    ..Previous studies of the Amazonian tree Dinizia excelsa (Fabaceae) found African honeybees (Apis mellifera scutellata) as the predominant pollinators of trees in highly disturbed ..
  90. ncbi Cross-species amplification of soybean (Glycine max) simple sequence repeats (SSRs) within the genus and other legume genera: implications for the transferability of SSRs in plants
    R Peakall
    Division of Botany and Zoology, Australian National University, Canberra, Australia
    Mol Biol Evol 15:1275-87. 1998
    ....
  91. ncbi Orphan legume crops enter the genomics era!
    Rajeev K Varshney
    International Crops Research Institute for Semi Arid Tropics, Patancheru 502324, A P, India
    Curr Opin Plant Biol 12:202-10. 2009
    ..The focus of these activities is the development of genome-scale data sets that can be used in high-throughput approaches to facilitate genomics-assisted breeding in these legumes...
  92. pmc Reversible calcium-regulated stopcocks in legume sieve tubes
    M Knoblauch
    Institut für Allgemeine Botanik und Pflanzenphysiologie, Justus Liebig Universitat, Senckenbergstrasse 17 21, D 35390 Giessen, Germany
    Plant Cell 13:1221-30. 2001
    Sieve tubes of legumes (Fabaceae) contain characteristic P-protein crystalloids with controversial function. We studied their behavior by conventional light, electron, and confocal laser scanning microscopy...
  93. ncbi Antitumor activity of Cratylia mollis lectin encapsulated into liposomes
    Cesar A S Andrade
    Laboratorio de Imunopatologia Keizo Asami, Universidade Federal de Pernambuco, Grupo de Sistemas de Liberação Controlada de Medicamentos, Cidade Universitaria, Recife, PE, Brazil
    Int J Pharm 278:435-45. 2004
    ..In particular, histopathological analysis revealed that treatment with Cra-loaded liposomes prevented Cra cytotoxicity in the liver and kidney of animals...
  94. ncbi Diversity and productivity in a long-term grassland experiment
    D Tilman
    Department of Ecology, Evolution and Behavior, University of Minnesota, St Paul, MN 55108, USA
    Science 294:843-5. 2001
    ....
  95. pmc Effect of manganese toxicity on the proteome of the leaf apoplast in cowpea
    Marion M Fecht-Christoffers
    Institute of Plant Nutrition, University of Hannover, Herrenhauser Strasse 2, 30419 Hannover, Germany
    Plant Physiol 133:1935-46. 2003
    ..The specific role of apoplastic PODs in the response of plants to Mn stress is discussed...
  96. ncbi Identification of volatiles that are used in discrimination between plants infested with prey or nonprey herbivores by a predatory mite
    Jetske G de Boer
    Laboratory of Entomology, Wageningen University PO Box 8031, 6700 EH Wageningen, The Netherlands
    J Chem Ecol 30:2215-30. 2004
    ..Our data show that specific compounds from complex herbivore-induced volatile blends can play an important role in the selective foraging behavior of natural enemies of herbivorous arthropods...
  97. pmc Sequencing and analysis of the gene-rich space of cowpea
    Michael P Timko
    Department of Biology, University of Virginia, Charlottesville, Virginia 22903, USA
    BMC Genomics 9:103. 2008
    ..With a nuclear genome size estimated at ~620 Mb, the cowpea genome is an ideal target for reduced representation sequencing...
  98. ncbi Integration of simple sequence repeat (SSR) markers into a molecular linkage map of common bean (Phaseolus vulgaris L.)
    K Yu
    Agriculture and Agri Food Canada, Greenhouse and Processing Crops Research Center, Harrow, Ontario
    J Hered 91:429-34. 2000
    ..These SSR markers were stable and easy to assay by polymerase chain reaction (PCR). They should be useful markers for genetic mapping, genotype identification, and marker-assisted selection of common beans...
  99. ncbi Earthworms and legumes control litter decomposition in a plant diversity gradient
    Alexandru Milcu
    NERC Centre for Population Biology, Division of Biology, Imperial College, Silwood Park, Ascot SL5 7PY, United Kingdom
    Ecology 89:1872-82. 2008
    ..and legumes function as keystone organisms for grassland decomposition processes and presumably contribute to the recorded increase in primary productivity with increasing plant diversity...
  100. pmc A 64 kDa sucrose binding protein is membrane-associated and tonoplast-localized in developing mung bean seeds
    Junqi Wang
    Department of Biology and Centre for Cell and Development Biology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
    J Exp Bot 60:629-39. 2009
    ..This study thus shows convincing evidence of tonoplast-localization of a plant SBP for its future functional characterization and provides a model of studying non-integral membrane proteins associated with the tonoplasts in plant cells...
  101. pmc Glutathione reductase in leaves of cowpea: cloning of two cDNAs, expression and enzymatic activity under progressive drought stress, desiccation and abscisic acid treatment
    Dominique Contour-Ansel
    Laboratoire d Ecophysiologie Moléculaire, UMR 137 BioSol Université Paris 12, 61 Avenue du General de Gaulle, F 94010 Créteil Cedex
    Ann Bot 98:1279-87. 2006
    ..The aim of this work was to study the variations in cytosolic and dual-targeted GR gene expression in the leaves of cowpea plants submitted to progressive drought, rapid desiccation and application of exogenous abscisic acid (ABA)...

Research Grants46

  1. CHEMISTRY OF NOVEL NATURAL INHIBITORS OF CARCINOGENESIS
    John Cassady; Fiscal Year: 1991
    ....
  2. Biological and chemical activity of Trifolium pratense
    Nancy Booth; Fiscal Year: 2003
    DESCRIPTION (Provided by applicant): The focus of this research is the investigation of Trifolium pratense L. (Fabaceae) (TP; red clover) for use in women?s cardiovascular health...
  3. Mammalian Lactoferrin Receptors: Structure and Function
    Bo Lonnerdal; Fiscal Year: 2007
    ..Overall, our understanding of the physiological significance of Lf and its receptor will be increased. ..
  4. Human Gut Microflora Profiling for Population Studies
    Johanna Lampe; Fiscal Year: 2006
    ..abstract_text> ..
  5. Breast Cancer, Benign Breast Disease, and Isoflavone Metabolism in Chinese Women
    Johanna Lampe; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
  6. Breast and Bone Density: Impact of Colonic Environment
    Johanna Lampe; Fiscal Year: 2006
    ..If equol-producer phenotype can predict differences in cumulative estrogen exposure / metabolism, it may serve as an early marker of breast cancer risk. ..
  7. Identification of biomarkers of fatty acid intake
    Hannia Campos; Fiscal Year: 2002
    ..abstract_text> ..
  8. HOST GENES AND COLONIC BACTERIA--PROBING FOR INHERITANCE
    Johanna Lampe; Fiscal Year: 2002
    ..If we can establish that the equol-producer phenotype is an inherited trait, we can then work to identify the associated genotype and determine more effectively whether this is a biomarker of breast cancer risk. ..
  9. Anti-GM1b IgM for Detection of Localized Prostate Cancer
    Mepur Ravindranath; Fiscal Year: 2005
    ....
  10. NUTRITIONAL BIOCHEMISTRY AND EPIDEMIOLOGY OF CANCER
    Steven Zeisel; Fiscal Year: 2006
    ..We are requesting two postdoctoral and six predoctoral trainee positions each year for this purpose. ..
  11. GLUTATHIONE TRANSFERASES IN HUMANS: DIETARY INFLUENCES
    Johanna Lampe; Fiscal Year: 2006
    ..abstract_text> ..
  12. An Exploratory Center for Obesity Research (RMI)
    Adam Drewnowski; Fiscal Year: 2006
    ..By promoting interagency collaborations, these efforts will help the NIH develop a roadmap on how to effectively translate research findings into national, state, and local health policy. [unreadable] [unreadable]..
  13. ALCOHOL EFFECT ON HUMAN LACTATION AND INFANT BEHAVIOR
    JULIE MENNELLA; Fiscal Year: 2007
    ..AIM 3: To explore the role of early experiences with ethanol in mothers' milk and the emotional context of such experiences, on the recognition of, and preference for, the sensory properties of ethanol ..
  14. Clinical Trial of Dietary Protein on Blood Pressure
    Jiang He; Fiscal Year: 2006
    ..Results from the proposed study may provide the scientific evidence for protein supplementation recommendations for the prevention and treatment of hypertension in the general population. ..
  15. NEUROTOXIC SUPERFUND CHEMICALS AND BIOMAKERS
    Peter Spencer; Fiscal Year: 2007
    ..abstract_text> ..
  16. Intergenerational Resemblances in Eating: the CSFII
    Sibylle Kranz; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  17. SECRETIONS OF ARTHROPODS
    Thomas Eisner; Fiscal Year: 2008
    ..Insects are major vectors of disease. An understanding of how insects depend on natural products for regulation of their biotic interactions is of broad applied significance to both medicine and agriculture. [unreadable] [unreadable]..
  18. UGT Polymorphisms and Hormonally-Mediated Biomarkers in Premenopausal Women
    Johanna Lampe; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  19. Lung Cancer Chemoprevention using Deguelin
    Ho Young Lee; Fiscal Year: 2008
    ..abstract_text> ..
  20. Molecular Target Focused Discovery of Anticancer Drugs
    GEORGE PETTIT; Fiscal Year: 2007
    ..In summary, the proposed research will be sharply aimed at the discovery and very rapid development of new anticancer drugs for the NCI programs direct at improving human cancer treatments. ..
  21. Toddler Feeding Styles
    Maureen M Black; Fiscal Year: 2010
    ..abstract_text> ..
  22. Energy Balance and Breast Cancer in Black & White Women
    Ellen Velie; Fiscal Year: 2006
    ..abstract_text> ..
  23. A Population Based Study of Birth Characteristics and Maternal Breast Cancer
    Ellen Velie; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  24. Evolution of Estrogen Receptor-Ligand Interactions
    Jennifer Fox; Fiscal Year: 2006
    ..Such an experimental system will allow the rigorous testing of hypotheses about ER-ligand structure function relationships and the dynamics of receptor-ligand coevolution. ..
  25. Serum IGFs--Effects of a Soy Intervention in Humans
    Johanna Lampe; Fiscal Year: 2002
    ..It provides an ideal design to evaluate the effects of isoflavones on the IGF system and to explore relationships between IGFs and colonic epithelial cell proliferation in humans. ..
  26. Nutritional Supplements and Cancer Chemoprevention
    JOHN PEZZUTO; Fiscal Year: 2002
    ..Attracting the attention of these participants should provide a valuable pedagogical experience and help to foster additional progress in the field of cancer chemoprevention. ..
  27. Hormone Status Postmenopause: Colonic Bacterial Effects
    Johanna Lampe; Fiscal Year: 2003
    ..The results of this study will provide novel data regarding the relationship of the equol-producer phenotype, a marker of colonic nticrofloral environment, to lifetime estrogen exposure. ..
  28. Glucuronidation in Humans--Genotypes and Phenotypes
    Johanna Lampe; Fiscal Year: 2004
    ..The randomized cross-over design will allow us to test efficiently for diet effects within individuals, as well as for gene-by-diet and sex-by-diet interactions. ..
  29. DIET SALT, CALCIUM KIDNEY STONES, BONE IN STONE FORMERS
    Linda Massey; Fiscal Year: 2001
    ..Reduction of dietary NaC1 from typical intakes of 200 mmol/day to an intake of 50 mmol/day may decrease the risk of recurrence of calcium-containing kidney stones and slow rates of bone loss, thus reducing risk of osteoporosis as well. ..
  30. DNA Damage: Fruit & Vegetable Effects in a Feeding Trial
    Johanna Lampe; Fiscal Year: 2005
    ..The existing intervention provides an ideal design in which to evaluate the relationships between biotransformation enzyme systems and DNA damage in humans. ..
  31. Risk of HTN Young Adult Lifestyle & Parental Influence
    MARGARET SAVOCA; Fiscal Year: 2005
    ..This innovative approach will identify relevant intervention points for reducing the risk of hypertension among young African Americans. ..
  32. DIETARY FATTY ACIDS, PPAR ACTIVATED GENES, AND CHD
    HANNAI CAMPOS; Fiscal Year: 2005
    ..Because polyunsaturated FAs are important as activators of PPARs and their capacity to regulate gene expression at the level of transcription, this metabolic system is a suitable candidate for the proposed study. ..
  33. ANTI-GANGLIOSIDE IgM IN DIAGNOSING PROSTATE CANCER
    Mepur Ravindranath; Fiscal Year: 2006
    ..An active collaboration with Pacific Urology Institute is ongoing and will continue to be a participant in this study. ..
  34. Prenatal Drug Exposure: Effects on Adolescent Brain and Behavioral Development
    Maureen Black; Fiscal Year: 2009
    ..This application examines adacemic performance, socio-emotional functioning, and drug use among adolescents exposed to cocaine and/or heroin prenatally ..
  35. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2003
    ..This study will provide the most complete data set to study numerous hypotheses relating genes, diet, and CHD, and could lead to specific targeted interventions for reducing the development of CHD. ..
  36. SYNTHESIS OF BIOACTIVE ALKALOIDS
    James White; Fiscal Year: 2006
    ..A plan is presented for the synthesis of this complex heptacyclic molecule which envisions a thio-Claisen rearrangement as the key step for building the vicinal quaternary carbons of this structure. ..
  37. Genetic Epidemiology of Blood Pressure Intervention
    Jiang He; Fiscal Year: 2008
    ..In addition, identifying genes related to salt-sensitivity and potassium-sensitivity of BP should enable the discovery of new pharmaceutical treatment for hypertension. [unreadable] [unreadable] [unreadable]..
  38. Diethanolamine, brain development and adult memory
    Steven Zeisel; Fiscal Year: 2006
    ..abstract_text> ..
  39. Phytoestrogens and breast cancer risk
    Susan McCann; Fiscal Year: 2006
    ..These investigations, combining retrospective and experimental designs, as well as genetic analyses, will help to elucidate the role of dietary phytoestrogen intake in the etiology of a hormone- sensitive cancer. ..
  40. Molecular Target Focused Discovery of Anticancer Drugs
    George R Pettit; Fiscal Year: 2010
    ....
  41. Race/Socioeconomic Area Characteristics & Cancer-Detroit
    Ellen Velie; Fiscal Year: 2005
    ..abstract_text> ..
  42. Sodium and Cardiovascular Disease in Patients with Chronic Kidney Disease
    Jiang He; Fiscal Year: 2010
    ....
  43. RHIZOBIAL LIPOPOLYSACCHARIDES ESSENTIAL FOR INFECTION
    Russell W Carlson; Fiscal Year: 2010
    ..create specific LPS mutants and characterize their structural and symbiotic phenotypes, and (3.) determine how a 27OHC28:0-lacking mutant, acpXL::kan, is able to activate an alternative mechanism within the host cell. ..
  44. Bacillus anthracis cell surface carbohydrates
    Russell Carlson; Fiscal Year: 2004
    ..Russell Carlson at the Complex Carbohydrate Research Center at the University of Georgia, Dr. David Stephens at Emory University, and Dr. Conrad Quinn at the Centers for Disease Control. ..
  45. ZINC AND IRON SUPPLEMENTATION: IMPACT ON DEVELOPMENT
    Maureen Black; Fiscal Year: 2002
    ..The results have important public health implications regarding the timing of micronutrient supplementation and the relationship between micronutrient deficiency and children's behavior and development. ..