mortierella

Summary

Summary: A genus of zygomycetous fungi of the family Mortierellaceae, order MUCORALES. Its species are abundant in soil and can cause rare infections in humans and animals. Mortierella alpinais is used for production of arachidonic acid.

Top Publications

  1. pmc Improvement of the fatty acid composition of an oil-producing filamentous fungus, Mortierella alpina 1S-4, through RNA interference with delta12-desaturase gene expression
    Seiki Takeno
    Laboratory of Fermentation Physiology and Applied Microbiology, Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto 606 8502, Japan
    Appl Environ Microbiol 71:5124-8. 2005
  2. ncbi Isolation and characterization of antagonistic fungi against potato scab pathogens from potato field soils
    Masahiro Tagawa
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    FEMS Microbiol Lett 305:136-42. 2010
  3. ncbi Repression of reserve lipid turnover in Cunninghamella echinulata and Mortierella isabellina cultivated in multiple-limited media
    S Papanikolaou
    Laboratory of General and Agricultural Microbiology, Department of Agricultural Biotechnology, Agricultural University of Athens, Athens, Greece
    J Appl Microbiol 97:867-75. 2004
  4. ncbi Biochemical characterization of GDP-L-fucose de novo synthesis pathway in fungus Mortierella alpina
    Yan Ren
    TEDA School of Biological Sciences and Biotechnology, Nankai University, Tianjin Economic Technological Development Area, Tianjin 300457, PR China
    Biochem Biophys Res Commun 391:1663-9. 2010
  5. ncbi Enzymatic hydrolysis and extraction of arachidonic acid rich lipids from Mortierella alpina
    Jiang Ying You
    College of Biotechnology and Pharmaceutical Engineering, State Key Laboratory of Materials Oriented Chemical Engineering, Nanjing University of Technology, No 5, Xinmofan Road, Nanjing 210009, People s Republic of China
    Bioresour Technol 102:6088-94. 2011
  6. ncbi Where is the unseen fungal diversity hidden? A study of Mortierella reveals a large contribution of reference collections to the identification of fungal environmental sequences
    László G Nagy
    Faculty of Science and Informatics, Department of Microbiology, University of Szeged, Közép fasor 52, H 6726 Szeged, Hungary
    New Phytol 191:789-94. 2011
  7. ncbi Semi-solid state fermentation of sweet sorghum for the biotechnological production of single cell oil
    Ch N Economou
    Department of Environmental and Natural Resources Management, University of Ioannina, G Seferi 2, 30100 Agrinio, Greece
    Bioresour Technol 101:1385-8. 2010
  8. ncbi Single cell oil (SCO) production by Mortierella isabellina grown on high-sugar content media
    Seraphim Papanikolaou
    Laboratory of General and Agricultural Microbiology, Department of Agricultural Biotechnology, Agricultural University of Athens, 75 Iera Odos, Votanikos, 11855 Athens, Greece
    Bioresour Technol 95:287-91. 2004
  9. ncbi Biochemical events leading to the diversion of carbon into storage lipids in the oleaginous fungi Mucor circinelloides and Mortierella alpina
    J P Wynn
    Centre for Advanced Lipid Research, Department of Biological Sciences, University of Hull, Hull HU6 7RX, UK
    Microbiology 147:2857-64. 2001
  10. ncbi Metabolism and synthesis of lipids in the polyunsaturated fatty acid-producing fungus Mortierella alliacea
    Worapol Jermsuntiea
    Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Higashi Hiroshima, Japan
    J Oleo Sci 60:11-7. 2011

Research Grants

Detail Information

Publications174 found, 100 shown here

  1. pmc Improvement of the fatty acid composition of an oil-producing filamentous fungus, Mortierella alpina 1S-4, through RNA interference with delta12-desaturase gene expression
    Seiki Takeno
    Laboratory of Fermentation Physiology and Applied Microbiology, Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto 606 8502, Japan
    Appl Environ Microbiol 71:5124-8. 2005
    An oleaginous fungus, Mortierella alpina 1S-4, is used commercially for arachidonic acid production...
  2. ncbi Isolation and characterization of antagonistic fungi against potato scab pathogens from potato field soils
    Masahiro Tagawa
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    FEMS Microbiol Lett 305:136-42. 2010
    ..isolates were related to members of the genera Penicillium, Eupenicillium, Chaetomium, Fusarium, Cladosporium, Mortierella, Kionochaeta, Pseudogymnoascus, and Lecythophora...
  3. ncbi Repression of reserve lipid turnover in Cunninghamella echinulata and Mortierella isabellina cultivated in multiple-limited media
    S Papanikolaou
    Laboratory of General and Agricultural Microbiology, Department of Agricultural Biotechnology, Agricultural University of Athens, Athens, Greece
    J Appl Microbiol 97:867-75. 2004
    ..biosynthesis and turnover (degradation) in two oleaginous Zygomycetes, namely Cunninghamella echinulata and Mortierella isabellina under various growth conditions...
  4. ncbi Biochemical characterization of GDP-L-fucose de novo synthesis pathway in fungus Mortierella alpina
    Yan Ren
    TEDA School of Biological Sciences and Biotechnology, Nankai University, Tianjin Economic Technological Development Area, Tianjin 300457, PR China
    Biochem Biophys Res Commun 391:1663-9. 2010
    b>Mortierella alpina is a filamentous fungus commonly found in soil, which is able to produce large amount of polyunsaturated fatty acids...
  5. ncbi Enzymatic hydrolysis and extraction of arachidonic acid rich lipids from Mortierella alpina
    Jiang Ying You
    College of Biotechnology and Pharmaceutical Engineering, State Key Laboratory of Materials Oriented Chemical Engineering, Nanjing University of Technology, No 5, Xinmofan Road, Nanjing 210009, People s Republic of China
    Bioresour Technol 102:6088-94. 2011
    ..enzymes (papain, pectinase, snailase, neutrase, alcalase and cellulase) were used to extract lipids from Mortierella alpina...
  6. ncbi Where is the unseen fungal diversity hidden? A study of Mortierella reveals a large contribution of reference collections to the identification of fungal environmental sequences
    László G Nagy
    Faculty of Science and Informatics, Department of Microbiology, University of Szeged, Közép fasor 52, H 6726 Szeged, Hungary
    New Phytol 191:789-94. 2011
    ..of increasing type strain sequencing effort on the number of identifiable MOTUs of the widespread soil fungus Mortierella. • We found a nearly linear relationship between the number of type strains sequenced and the number of ..
  7. ncbi Semi-solid state fermentation of sweet sorghum for the biotechnological production of single cell oil
    Ch N Economou
    Department of Environmental and Natural Resources Management, University of Ioannina, G Seferi 2, 30100 Agrinio, Greece
    Bioresour Technol 101:1385-8. 2010
    ..The microorganism used is the oleaginous fungus Mortierella isabellina, which is able to transform efficiently sugar to storage lipid...
  8. ncbi Single cell oil (SCO) production by Mortierella isabellina grown on high-sugar content media
    Seraphim Papanikolaou
    Laboratory of General and Agricultural Microbiology, Department of Agricultural Biotechnology, Agricultural University of Athens, 75 Iera Odos, Votanikos, 11855 Athens, Greece
    Bioresour Technol 95:287-91. 2004
    b>Mortierella isabellina cultivated in nitrogen-limited media presented remarkable cell growth (up to 35.9 g/l) and high glucose uptake even with high initial sugar concentrations (e.g. 100 g/l) in media...
  9. ncbi Biochemical events leading to the diversion of carbon into storage lipids in the oleaginous fungi Mucor circinelloides and Mortierella alpina
    J P Wynn
    Centre for Advanced Lipid Research, Department of Biological Sciences, University of Hull, Hull HU6 7RX, UK
    Microbiology 147:2857-64. 2001
    The biochemical events associated with the onset of lipid accumulation in Mucor circinelloides and Mortierella alpina, under conditions of nitrogen-limited growth, have been elucidated; they differ in key aspects from those described in ..
  10. ncbi Metabolism and synthesis of lipids in the polyunsaturated fatty acid-producing fungus Mortierella alliacea
    Worapol Jermsuntiea
    Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Higashi Hiroshima, Japan
    J Oleo Sci 60:11-7. 2011
    The fungal strain Mortierella alliacea YN-15 is a promising industrial producer of polyunsaturated fatty acids (PUFAs), in particular arachidonic acid...
  11. ncbi Evaluation of lipid accumulation from lignocellulosic sugars by Mortierella isabellina for biodiesel production
    Zhenhua Ruan
    Department of Biosystems and Agricultural Engineering, Michigan State University, East Lansing, MI 48824, USA
    Bioresour Technol 110:198-205. 2012
    The filamentous fungus Mortierella isabellina ATCC42613 was used to assess the conversion of different carbon sources (glucose, xylose, mixed glucose/xylose, acid and alkali treated corn stover hydrolysate) in submerged media to lipid...
  12. ncbi Identification of a novel fatty acid elongase with a wide substrate specificity from arachidonic acid-producing fungus Mortierella alpina 1S-4
    Eiji Sakuradani
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwakecho, Sakyo ku, Kyoto, 606 8502, Japan
    Appl Microbiol Biotechnol 84:709-16. 2009
    ..characterization of a gene (MALCE1) that encodes a fatty acid elongase from arachidonic acid-producing fungus Mortierella alpina 1S-4 are described...
  13. ncbi Gene cloning and functional analysis of a second delta 6-fatty acid desaturase from an arachidonic acid-producing Mortierella fungus
    Eiji Sakuradani
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwakecho, Sakyo ku, Kyoto 606 8502, Japan
    Biosci Biotechnol Biochem 67:704-11. 2003
    We demonstrated that Mortierella alpina 1S-4 has two delta 6-desaturases, which are involved in the desaturation of linoleic acid to gamma-linolenic acid...
  14. ncbi 2,4-Dichlorophenol degradation by the soil fungus Mortierella sp
    Ayami Nakagawa
    Green Tech Co, Ltd, Innoshima, Japan
    Biosci Biotechnol Biochem 70:525-7. 2006
    We investigated the degradation pathways and kinetics of 2,4-dichlorophenol (DCP) by an endemic soil fungus, Mortierella sp. (Zygomycetes). Mortierella sp. degraded 32% of added DCP (final concentration, 250 microM) within 1 h...
  15. ncbi A third fatty acid delta9-desaturase from Mortierella alpina with a different substrate specificity to ole1p and ole2p
    Donald A MacKenzie
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Microbiology 148:1725-35. 2002
    A third gene (Delta9-3) encoding a fatty acid Delta9-desaturase was isolated from the oil-producing fungus Mortierella alpina...
  16. ncbi Metabolism of daidzein by Nocardia species NRRL 5646 and Mortierella isabellina ATCC 38063
    Galal T Maatooq
    Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt
    Phytochemistry 66:1007-11. 2005
    ..b>Mortierella isabellina ATCC 38063 was able to metabolize daidzein to the unusual metabolite daidzein-4'-rhamnopyranoside.
  17. pmc Genome characterization of the oleaginous fungus Mortierella alpina
    Lei Wang
    TEDA School of Biological Sciences and Biotechnology, Nankai University, Tianjin Economic Technological Development Area, Tianjin, People s Republic of China
    PLoS ONE 6:e28319. 2011
    b>Mortierella alpina is an oleaginous fungus which can produce lipids accounting for up to 50% of its dry weight in the form of triacylglycerols. It is used commercially for the production of arachidonic acid...
  18. ncbi Establishment of an overall transformation system for an oil-producing filamentous fungus, Mortierella alpina 1S-4
    Seiki Takeno
    Laboratory of Fermentation Physiology and Applied Microbiology, Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, 606 8502, Kyoto, Japan
    Appl Microbiol Biotechnol 65:419-25. 2004
    Oil-producing fungus Mortierella alpina 1S-4 is an industrial strain...
  19. ncbi Evidence that the rate-limiting step for the biosynthesis of arachidonic acid in Mortierella alpina is at the level of the 18:3 to 20:3 elongase
    J P Wynn
    Lipid Research Group, Department of Biological Sciences, University of Hull, Hull HU6 7RX, UK
    Microbiology 146:2325-31. 2000
    b>Mortierella alpina, a fungus used commercially as a source of arachidonic acid, 20:4(n-6), has been examined to see if growth on lipid-based carbon sources leads to repression of either fatty acid biosynthesis and/or fatty acid ..
  20. ncbi Regulation of lipid accumulation in oleaginous micro-organisms
    C Ratledge
    Department of Biological Sciences, University of Hull, UK
    Biochem Soc Trans 30:1047-50. 2002
    ..ME activity correlates closely with lipid accumulation in two filamentous fungi, Mucor circinelloides and Mortierella alpina. When ME ceases to be active, lipid accumulation also stops...
  21. ncbi A novel psychrotrophic fungus, Mortierella minutissima, for D-limonene biotransformation
    Mariusz Trytek
    Department of Industrial Microbiology, Maria Curie Skłodowska University, Akademicka 19, 20 033 Lublin, Poland
    Biotechnol Lett 27:149-53. 2005
    Of 98 strains of moulds, isolated from arctic soils, Mortierella minutissima 01, grew the best on agar plates with limonene vapor. Perillyl alcohol and perillic acid were the main products of limonene biotransformation...
  22. ncbi Single cell oil production by Mortierella alpina
    Eiji Sakuradani
    Kyoto University, Japan
    J Biotechnol 144:31-6. 2009
    A filamentous fungus, Mortierella alpina 1S-4, was obtained, through extensive screening, as an potential producer of triacylglycerol containing C20 polyunsaturated fatty acids (PUFAs) such as arachidonic acid...
  23. ncbi Effect of glutamate on arachidonic acid production from Mortierella alpina
    W Z Lan
    School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China
    Lett Appl Microbiol 35:357-60. 2002
    To evaluate the effect of glutamate on arachidonic acid production from Mortierella alpina.
  24. ncbi Identification of Delta12-fatty acid desaturase from arachidonic acid-producing mortierella fungus by heterologous expression in the yeast Saccharomyces cerevisiae and the fungus Aspergillus oryzae
    E Sakuradani
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Osaka, Japan
    Eur J Biochem 261:812-20. 1999
    ..alpha-linolenic acid (Delta9, Delta12, Delta15-18 : 3), a cDNA was cloned from the filamentous fungal strain, Mortierella alpina 1S-4, which is used industrially to produce arachidonic acid...
  25. ncbi A novel fungal omega3-desaturase with wide substrate specificity from arachidonic acid-producing Mortierella alpina 1S-4
    Eiji Sakuradani
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwakecho, Sakyo ku, Kyoto, 606 8502, Japan
    Appl Microbiol Biotechnol 66:648-54. 2005
    A filamentous fungus, Mortierella alpina 1S-4, is capable of producing not only arachidonic acid (AA; 20:4n-6) but also eicosapentaenoic acid (EPA; 20:5n-3) below a cultural temperature of 20 degrees C...
  26. pmc Establishment of Agrobacterium tumefaciens-mediated transformation of an oleaginous fungus, Mortierella alpina 1S-4, and its application for eicosapentaenoic acid producer breeding
    Akinori Ando
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwakecho, Sakyo ku, Kyoto 606 8502, Japan
    Appl Environ Microbiol 75:5529-35. 2009
    Gene manipulation tools for an arachidonic-producing filamentous fungus, Mortierella alpina 1S-4, have not been sufficiently developed. In this study, Agrobacterium tumefaciens-mediated transformation (ATMT) was investigated for M...
  27. ncbi Polyunsaturated fatty acids (PUFAs) content of the fungus Mortierella alpina isolated from soil
    Sze Yuen Ho
    Department of Botany, The University of Hong Kong, Pokfulam Road, Hong Kong, People s Republic of China
    J Agric Food Chem 55:3960-6. 2007
    Twenty-five isolates of Mortierella spcies were prepared, which can be used for the production of polyunsaturated fatty acids (PUFAs)-rich oil for nutritional supplements...
  28. ncbi Fatty acid composition in lipid fractions lengthwise the mycelium of Mortierella isabellina and lipid production by solid state fermentation
    Stylianos Fakas
    Unit of Microbiology, Division of Genetics, Cell and Development Biology, Department of Biology, University of Patras, Patras, 265 04 GR, Greece
    Bioresour Technol 100:6118-20. 2009
    ..was investigated by analyzing the lipid composition lengthwise the mycelium of the oleaginous fungus Mortierella isabellina, a potential producer of gamma-linolenic acid (GLA)...
  29. ncbi Unusual fatty acid composition of cerebrosides from the filamentous soil fungus Mortierella alpina
    S G Batrakov
    Russian Research Centre, Hydrobios of Ministry of Health, ul Kosmonavtov 18, korp 2, Moscow 129301, Russia
    Chem Phys Lipids 117:45-51. 2002
    The cerebrosides produced by the soil filamentous fungus Mortierella alpina strain KG-1/95 account for about 13% of the total polar lipids extractable from lyophilised cells with chloroform/methanol mixtures...
  30. ncbi Multiple isoforms of malic enzyme in the oleaginous fungus, Mortierella alpina
    Ying Zhang
    Department of Biological Sciences, University of Hull, Hull, UK
    Mycol Res 112:725-30. 2008
    ..At least seven isoforms (A-G) of ME were identified in the oleaginous fungus, Mortierella alpina, using a specific activity stain following non-denaturing polyacrylamide gel electrophoresis (PAGE) of ..
  31. ncbi Enzymatic deacetylation of chitin by extracellular chitin deacetylase from a newly screened Mortierella sp. DY-52
    Young Ju Kim
    Glucosamine Saccharide Materials National Research Laboratory GSM NRL, Division of Applied Bioscience and Biotechnology, Institute of Agricultural Science and Technology, Chonnam National University, Gwangju 500 757, Korea
    J Microbiol Biotechnol 18:759-66. 2008
    ..The isolate was further identified as Mortierella sp., based on the morphological properties and the nucleotide sequence of its 18S rRNA gene...
  32. ncbi DGAT2 is a new diacylglycerol acyltransferase gene family: purification, cloning, and expression in insect cells of two polypeptides from Mortierella ramanniana with diacylglycerol acyltransferase activity
    K D Lardizabal
    Calgene Campus Monsanto, Davis, California 95616, USA
    J Biol Chem 276:38862-9. 2001
    ..which co-purified with DGAT activity, were isolated from the lipid bodies of the oleaginous fungus Mortierella ramanniana with a procedure consisting of dye affinity, hydroxyapatite affinity, and heparin chromatography...
  33. pmc Identification of a sterol Delta7 reductase gene involved in desmosterol biosynthesis in Mortierella alpina 1S-4
    Shuo Zhang
    Division of Applied Life of Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwakecho, Sakyo ku, Kyoto 606 8502, Japan
    Appl Environ Microbiol 73:1736-41. 2007
    Molecular cloning of the gene encoding sterol Delta7 reductase from the filamentous fungus Mortierella alpina 1S-4, which accumulates cholesta-5,24-dienol (desmosterol) as the main sterol, revealed that the open reading frame of this ..
  34. ncbi High-level production of arachidonic acid by fed-batch culture of Mortierella alpina using NH4OH as a nitrogen source and pH control
    Byung Hae Hwang
    Department of Molecular Science and Technology, Ajou University, San5, Woncheong dong, 442 749, Yeongtong Gu, Suwon, Republic of Korea
    Biotechnol Lett 27:731-5. 2005
    b>Mortierella alpina was grown in a fed-batch culture using a 12-l jar fermenter with an initial 8-l working volume containing 20 g glucose l-1 and 10 g corn-steep powder l-1. Glucose was intermittently fed to give 32 g l-1 at each time...
  35. ncbi Sexual reactions in Mortierellales are mediated by the trisporic acid system
    Christine Schimek
    Department of General Microbiology and Microbial Genetics, Institute of Microbiology, Friedrich Schiller University, Neugasse 24, D 07743 Jena, Germany
    Mycol Res 107:736-47. 2003
    Several species of Mortierella (Mortierellales, Zygomycota) were examined for substances regulating their sexual reactions...
  36. ncbi Improved arachidonic acids production from the fungus Mortierella alpina by glutamate supplementation
    L J Yu
    School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China
    Bioresour Technol 88:265-8. 2003
    The effect of various concentrations of glutamate on arachidonic acid (AA) production from Mortierella alpina in shaker flask culture was studied...
  37. pmc Cloning and molecular characterization of delta12-fatty acid desaturase gene from Mortierella isabellina
    Ming Chun Li
    Department of Microbiology, The College of Life Science, Nankai University, Tianjin, China
    World J Gastroenterol 12:3373-9. 2006
    To clone delta(12)-fatty acid desaturase gene of Mortierella isabellina and to functionally characterize this gene in vitro and in vivo.
  38. ncbi Identification of mutation sites on delta5 desaturase genes from Mortierella alpina 1S-4 mutants
    Takahiro Abe
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwakecho, Sakyo ku, Kyoto 606 8502, Japan
    J Biosci Bioeng 99:296-9. 2005
    ..sites on delta5 desaturase genes in delta5 desaturase-defective mutants derived from arachidonic acid-producing Mortierella alpina 1S-4 were identified...
  39. ncbi cDNA cloning and functional expression of alpha-glucosidase from Mortierella alliacea
    Y Tanaka
    Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, 1 3 1 Kagamiyama, 739 8530, Higashi Hiroshima, Japan
    Appl Microbiol Biotechnol 62:202-9. 2003
    We recently purified an alpha-glucosidase comprising 61-kDa and 31-kDa subunits from the fungus Mortierella alliacea and characterized its soluble starch-hydrolyzing activity...
  40. ncbi Cloning and sequencing of the ura3 and ura5 genes, and isolation and characterization of uracil auxotrophs of the fungus Mortierella alpina 1S-4
    Seiki Takeno
    Laboratory of Fermentation Physiology and Applied Microbiology, Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Japan
    Biosci Biotechnol Biochem 68:277-85. 2004
    The oil-producing fungus Mortierella alpina 1S-4 is an industrial strain...
  41. ncbi Spore germination in Mortierella alpina is associated with a transient depletion of arachidonic acid and induction of fatty acid desaturase gene expression
    C Lounds
    School of Biology, University of Nottingham, University Park, Nottingham, UK
    Arch Microbiol 188:299-305. 2007
    b>Mortierella alpina is an oleaginous filamentous fungus whose vegetative mycelium is known to accumulate triglyceride oil containing large amounts of arachidonic acid (ARA 20:4, n - 6)...
  42. ncbi Production of arachidonic acid and dihomo-gamma-linolenic acid from glycerol by oil-producing filamentous fungi, Mortierella in the ARS culture collection
    Ching T Hou
    Microbial Genomics and Bioprocessing Research Unit, National Center for Agricultural, Utilization Research, Agricultural Research Service, United States Department of Agriculture, 1815 North University Street, Peoria, IL 61604, USA
    J Ind Microbiol Biotechnol 35:501-6. 2008
    The filamentous fungi of the genus Mortierella are known to produce arachidonic acid from glucose, and the species alpina is currently used in industrial production of arachidonic acid in Japan...
  43. ncbi [Isolation and functional identification of delta 5 desaturase gene from Mortierella alpina]
    Min Zhu
    Huazhong University of Science and Technology, School of Life Science and Technology, Wuhan 430074, China
    Yi Chuan Xue Bao 32:986-92. 2005
    ..Complete cDNA encoding putative delta5 fatty acyl desaturase was isolated from Mortierella alpina M6 via RT-PCR. The full length cDNA consisted of 1366 nucleotides encoding 446 amino acids...
  44. ncbi Genetic analysis of cytochrome b5 from arachidonic acid-producing fungus, Mortierella alpina 1S-4: cloning, RNA editing and expression of the gene in Escherichia coli, and purification and characterization of the gene product
    M Kobayashi
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwake cho, Sakyo ku, Kyoto, 606 8502, Japan
    J Biochem 125:1094-103. 1999
    Information on the amino acid sequences of the internal peptide fragments of cytochrome b5 from Mortierella hygrophila was used to prepare synthetic oligonucleotides as primers for the polymerase chain reaction...
  45. ncbi A novel two-step fermentation process for improved arachidonic acid production by Mortierella alpina
    Ming Jie Jin
    College of Life Science and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing, 210009, People s Republic of China
    Biotechnol Lett 30:1087-91. 2008
    A novel two-step fermentation process was developed to enhance arachidonic acid (ARA) production by Mortierella alpina ME-1 in a 5 l fermentor. Agitation speed and aeration rate were adjusted from 180 to 40 rpm and from 0...
  46. ncbi Identification of mutation sites on delta6 desaturase genes from Mortierella alpina 1S-4 mutants
    Takahiro Abe
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto
    Biosci Biotechnol Biochem 69:1021-4. 2005
    Three Delta6 desaturase-defective mutants, designated YB214, HR95, and ST66, were newly isolated from Mortierella alpina 1S-4, after treating wild-type spores with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)...
  47. ncbi Expression of fungal desaturase genes in cultured mammalian cells
    B Kelder
    Edison Biotechnology Institute and Department of Biomedical Sciences, Ohio University, Athens, USA
    Mol Cell Biochem 219:7-11. 2001
    ....
  48. ncbi Molecular evidence that the rate-limiting step for the biosynthesis of arachidonic acid in Mortierella alpina is at the level of an elongase
    Seiki Takeno
    Laboratory of Fermentation Physiology and Applied Microbiology, Graduate School of Agriculture, Kyoto University, Kyoto 606 8502, Japan
    Lipids 40:25-30. 2005
    The oil-producing fungus Mortierella alpina 1S-4 is an industrial strain for arachidonic acid (AA) production...
  49. ncbi Disruption of the fatty acid Delta6-desaturase gene in the oil-producing fungus Mortierella isabellina by homologous recombination
    Xuewei Zhang
    College of Life Science, Nankai University, 300071, Tianjin, People s Republic of China
    Curr Microbiol 55:128-34. 2007
    The gamma-linolenic acid-producing fungus Mortierella isabellina 6-22 is an important industrial strain...
  50. pmc Identification of an NADH-cytochrome b(5) reductase gene from an arachidonic acid-producing fungus, Mortierella alpina 1S-4, by sequencing of the encoding cDNA and heterologous expression in a fungus, Aspergillus oryzae
    E Sakuradani
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Appl Environ Microbiol 65:3873-9. 1999
    ..information for bovine and yeast NADH-cytochrome b(5) reductases (CbRs), a DNA fragment was cloned from Mortierella alpina 1S-4 after PCR amplification...
  51. ncbi [Growth-coupled lipid synthesis in Mortierella alpina LPM 301, a producer of arachidonic acid]
    V K Eroshin
    Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, pr Nauki 5, Pushchino, Moscow Oblast, 142290 Russia
    Mikrobiologiia 71:200-4. 2002
    b>Mortierella alpina LPM 301, a producer of arachidonic acid (ARA), was found to possess a unique property of intense lipid synthesis in the period of active mycelium growth...
  52. ncbi Production of 5,8,11-eicosatrienoic acid by a delta5 and delta6 desaturation activity-enhanced mutant derived from a delta12 desaturation activity-defective mutant of Mortierella alpina 1S-4
    E Sakuradani
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwakecho, Sakyo ku, Kyoto 606 8502, Japan
    Appl Microbiol Biotechnol 60:281-7. 2002
    Enhanced production of 5,8,11-eicosatrienoic acid (Mead acid, 20:3omega9) was attained with a mutant fungus, Mortierella alpina JT-180, derived from delta12 desaturation activity-defective and delta6 desaturation activity-enhanced M...
  53. ncbi Isolating Mortierella alpina strains of high yield of arachidonic acid
    M Zhu
    School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China
    Lett Appl Microbiol 39:332-5. 2004
    ..To develop a fast isolation method for arachidonic acid-producing fungi of high yield...
  54. ncbi Functional characterization of Delta9 and omega9 desaturase genes in Mortierella alpina 1S-4 and its derivative mutants
    Takahiro Abe
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwakecho, Sakyo ku, Kyoto, 606 8502, Japan
    Appl Microbiol Biotechnol 70:711-9. 2006
    Cloning and characterization of the Delta9 desaturase (Delta9I) gene of a fungus, Mortierella alpina 1S-4, was previously reported. In this study, two genes encoding Delta9 desaturase homologs were isolated from this fungus...
  55. ncbi Appearance of smaller lipid bodies and protein kinase activation in the lipid body fraction are induced by an increase in the nitrogen source in the Mortierella fungus
    Yasushi Kamisaka
    Lipid Engineering Research Group, Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305 8566
    J Biochem 135:269-76. 2004
    We studied the regulation of lipid body biogenesis in the oleaginous fungus Mortierella ramanniana var...
  56. ncbi Biotransformations of the cardiovascular drugs mexrenone and canrenone
    Carol L Preisig
    MDS Pharma Services, 11804 North Creek Parkway South, Bothell, Washington 98011, USA
    J Nat Prod 66:350-6. 2003
    ..5) were isolated as major products produced by the Beauveria bassiana ATCC 13144 bioconversion (3) and the Mortierella isabellina bioconversion (4 and 5), respectively...
  57. ncbi Polyunsaturated fatty acids production with a solid-state column reactor
    Hung Der Jang
    Department of Food Science, Yuanpei University, Hsinchu 300, Taiwan
    Bioresour Technol 99:6181-9. 2008
    ..the potential production of polyunsaturated fatty acids (PUFAs), a solid-state column reactor of rice bran with Mortierella alpina was used. The optimal conditions for PUFAs production were rice bran supplementation with 3...
  58. ncbi Purification and characterization of a novel fungal alpha-glucosidase from Mortierella alliacea with high starch-hydrolytic activity
    Yoshio Tanaka
    Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, 1 3 1 Kagamiyama, Higashi Hiroshima 739 8530, Japan
    Biosci Biotechnol Biochem 66:2415-23. 2002
    The fungal strain Mortierella alliacea YN-15 is an arachidonic acid producer that assimilates soluble starch despite having undetectable alpha-amylase activity...
  59. ncbi Biosynthesis of triacylglycerol molecular species in an oleaginous fungus, Mortierella ramanniana var. angulispora
    Manoj G Pillai
    Lipid Engineering Research Group, Research Institute of Biological Resources, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305 8566, Japan
    J Biochem 132:121-6. 2002
    The incorporation of radiolabeled lipid precursors into triacylglycerol (TG) molecular species in Mortierella ramanniana var. angulispora, an oleaginous fungus, was studied to determine the biosynthetic pathways for TG molecular species...
  60. ncbi Degradation of phenol and cresols at low temperatures using a suspended-carrier biofilm process
    N Perron
    Department of Biotechnology, Center for Chemistry and Chemical Engineering, Lund University, P O Box 124, SE 221 00 Lund, Sweden
    Chemosphere 55:45-50. 2004
    ..The fungus Mortierella sarnyensis Mil'ko dominated the microflora in the first reactor, while bacteria dominated in the second reactor...
  61. ncbi In vivo metabolism of [14C]ruboxistaurin in dogs, mice, and rats following oral administration and the structure determination of its metabolites by liquid chromatography/mass spectrometry and NMR spectroscopy
    Robert J Barbuch
    Eli Lilly Research Laboratories, Indianapolis, IN, USA
    Drug Metab Dispos 34:213-24. 2006
    ..4 (regioisomer of 3 which did not correlate to metabolites found in vivo) were produced using a microbe, Mortierella zonata...
  62. ncbi Mycelial pellet intrastructure and visualization of mycelia and intracellular lipid in a culture of Mortierella alpina
    T Hamanaka
    Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University, Ohya, Japan
    Appl Microbiol Biotechnol 56:233-8. 2001
    The intrastructure of mycelial pellets of Mortierella alpina, which accumulate fatty acids in mycelia, was visualized following labeling with fluorescein isothiocyanate (FITC) and Nile red using fluorescence microscopy...
  63. ncbi In vitro susceptibility to fungicides by invertebrate-pathogenic and saprobic fungi
    Christian Luz
    DMIPP, Instituto de Patologia Tropical e Saude Publica, Universidade Federal de Goias, CP 131, 74001 970 Goiania, GO, Brasil
    Mycopathologia 164:39-47. 2007
    ..Cladosporium cladosporioides, Cunninghamella echinulata, Fusarium roseum, Gliocladium sp., Mortierella isabellina, Mucor plumbeus, Rhizopus arrhizus and Trichothecium roseum) originating mostly from tree-hole ..
  64. pmc Impact of biocontrol Pseudomonas fluorescens CHA0 and a genetically modified derivative on the diversity of culturable fungi in the cucumber rhizosphere
    M Girlanda
    Dipartimento di Biologia Vegetale and CSMT CNR, Viale P A Mattioli 25, 10125 Torino, Italy
    Appl Environ Microbiol 67:1851-64. 2001
    ..fungal species (mainly belonging to the genera Paecilomyces, Phialocephala, Fusarium, Gliocladium, Penicillium, Mortierella, Verticillium, Trichoderma, Staphylotrichum, Coniothyrium, Cylindrocarpon, Myrothecium, and Monocillium) were ..
  65. ncbi New bioactive fatty acids
    Ching T Hou
    Microbial Genomics and Bioprocessing Research Unit, National Center for Agricultural Utilization Research, ARS, USDA 1815 N University Street, Peoria, IL 61604 USA
    Asia Pac J Clin Nutr 17:192-5. 2008
    ..We also screened 12 Mortierella fungal strains from the ARS Culture Collection for the production of bioactive fatty acids such as dihomo-gama-..
  66. ncbi Inhibitory effects of cysteine and cysteine derivatives on germination of sporangiospores and hyphal growth of different Zygomycetes
    Laszlo Galgoczy
    Department of Microbiology, Faculty of Science and Informatics, University of Szeged, Közép fasor 52, 6726 Szeged, Hungary
    Mycopathologia 168:125-34. 2009
    ..on 20 fungal isolates representing 16 genera (Absidia, Actinomucor, Backusella, Gilbertella, Micromucor, Mortierella, Mucor, Mycotypha, Phycomyces, Rhizomucor, Rhizopus, Saksenaea, Syncephalastrum, Thamnostylum, Umbellopsis, and ..
  67. ncbi Influence of roadside pollution on the phylloplane microbial community of Alnus nepalensis (Betulaceae)
    S R Joshi
    Department of Biotechnology and Bioinformatics, School of Life Sciences, North Eastern Hill University, Mawkynroh, Umshing, Shillong 793022, Meghalaya, India
    Rev Biol Trop 56:1521-9. 2008
    ..nepalensis (polluted site 16 species; unpolluted site 28 species). Some fungal forms like Mortierella sp., Fusarium oxysporum and Aureobasidium pollulans were dominant in the polluted site...
  68. ncbi [Nematophagous fungi of Toxocara canis eggs in a public park of La Plata, Argentina]
    Cecilia Gortari
    CIC PBA and CINDEFI CONICET UNLP Facultad de Ciencias Exactas, UNLP, La Plata, Argentina
    Rev Iberoam Micol 24:24-8. 2007
    ..antagonistic fungal genera were identified: Acremonium, Aspergillus, Chrysosporium, Fusarium, Humicola, Mortierella, Paecilomyces and Penicillium. A prevalence of 70% was detected for nematode eggs, of 33% for Toxocara spp...
  69. ncbi Assessment of alcohol percentage test for fungal surface hydrophobicity measurement
    H W Chau
    Department of Soil Science, University of Saskatchewan, Saskatoon, SK, Canada
    Lett Appl Microbiol 50:295-300. 2010
    ..To determine whether assessing the penetration of solutions with different concentrations of ethanol (alcohol percentage test: APT) on fungal surfaces is effective in characterization of hydrophobicity on fungal surfaces...
  70. ncbi Cloning, molecular characterization and expression of a cDNA encoding a functional NADH-cytochrome b5 reductase from Mucor racemosus PTCC 5305 in E. coli
    Neda Setayesh
    Laboratory of Genetic Engineering, Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 14174, Iran
    Biol Res 42:137-46. 2009
    ..from ATG and ending with TAG stop codon encoded 228 amino acids and displayed the closest similarity (73%) with Mortierella alpina cb5r...
  71. ncbi In vitro interaction between suramin and fluvastatin against clinically important Zygomycetes
    Laszlo Galgoczy
    Department of Microbiology, University of Szeged, Hungary
    Mycoses 52:447-53. 2009
    ..In the present work, 15 fungal isolates representing eight clinically important genera (Absidia, Micromucor, Mortierella, Mucor, Rhizomucor, Rhizopus, Saksenaea and Syncephalastrum) were investigated...
  72. ncbi Fungal bioconversion of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4-dichlorophenol (2,4-DCP)
    T Vroumsia
    Département des Sciences de l Environment, Faculte des Sciences, Université de Ngaoundéré, B P 454 Ngaoundéré, Cameroun
    Chemosphere 60:1471-80. 2005
    ..After 5 days of cultivation, the best results were obtained with Aspergillus penicilloides and Mortierella isabellina for 2,4-D and with Chrysosporium pannorum and Mucor genevensis for 2,4-DCP...
  73. ncbi Sensitivity of different zygomycetes to the Penicillium chrysogenum antifungal protein (PAF)
    Laszlo Galgoczy
    Department of Microbiology, Faculty of Sciences, University of Szeged, P O Box 533, H 6701, Szeged, Hungary
    J Basic Microbiol 45:136-41. 2005
    ..of 21 fungal isolates from 15 different genera (Absidia, Actinomucor, Cokeromyces, Gilbertella, Micromucor, Mortierella, Mucor, Mycotypha, Rhizomucor, Rhizopus, Saksenaea, Syncephalastrum, Thamnostylum, Umbelopsis and Zygorhynchus) ..
  74. ncbi Purification and characterization of thermostable alpha-galactosidase from Ganoderma lucidum
    Thida Sripuan
    Department of Chemistry, Faculty of Science, Chiang Mai University, Thailand
    Biosci Biotechnol Biochem 67:1485-91. 2003
    ..Its N-terminal amino acid sequence was similar to that of Mortierella vinacea alpha-galactosidase...
  75. pmc Solar UV-B radiation inhibits the growth of Antarctic terrestrial fungi
    Kevin A Hughes
    British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge CB3 0ET, UK
    Appl Environ Microbiol 69:1488-91. 2003
    ..Verticillium sp., and Mortierella parvispora, each isolated from Antarctic terrestrial habitats, were examined on an agar medium in the natural ..
  76. ncbi Malic enzyme: the controlling activity for lipid production? Overexpression of malic enzyme in Mucor circinelloides leads to a 2.5-fold increase in lipid accumulation
    Ying Zhang
    Department of Biological Sciences, University of Hull, Hull HU6 7RX, UK
    Microbiology 153:2013-25. 2007
    ..genes encoding the isoform of ME involved in fatty acid synthesis were identified in Mucor circinelloides and Mortierella alpina, two commercially useful oil-producing fungi, using degenerate primers...
  77. ncbi Cloning and functional characterisation of polyunsaturated fatty acid elongases of marine and freshwater teleost fish
    Morris K Agaba
    Institute of Aquaculture, University of Stirling, Stirling FK9 4LA, Scotland, United Kingdom
    Comp Biochem Physiol B Biochem Mol Biol 142:342-52. 2005
    ..A Mortierella alpina cDNA polyunsaturated fatty acid elongase sequence identified mammalian, amphibian, zebrafish and insect ..
  78. ncbi Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members
    S Cases
    Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94143, USA
    J Biol Chem 276:38870-6. 2001
    ..and characterized a second mammalian DGAT, DGAT2, which was identified by its homology to a DGAT in the fungus Mortierella rammaniana...
  79. ncbi Ecological study of the fungal populations of the acidic Tinto River in southwestern Spain
    A I López-Archilla
    Department of Ecology, Faculty of Sciences, Independent University of Madrid, Cantoblanco, Madrid 28049, Spain
    Can J Microbiol 50:923-34. 2004
    ..we characterized strains of the ascomycete genera Lecythophora and Acremonium and of the zygomycete genus Mortierella, all of them capable of growing in medium amended with river water...
  80. ncbi Safety evaluation of sources of docosahexaenoic acid and arachidonic acid for use in infant formulas in newborn piglets
    Russell J Merritt
    Ross Products Division, Abbott Laboratories, 625 Cleveland Avenue, Columbus, OH 43215, USA
    Food Chem Toxicol 41:897-904. 2003
    ..The ARA-rich oil was from a fermentation product of Mortierella alpina (40 wt.% fatty acids as ARA) and DHA was from high DHA tuna oil (25 wt.% fatty acids as DHA)...
  81. ncbi Tolerance of Antarctic soil fungi to hydrocarbons
    Kevin A Hughes
    British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge CB3 0ET, United Kingdom
    Sci Total Environ 372:539-48. 2007
    ..Fungal growth rates of Mollisia sp., Penicillium commune, Mortierella sp., Trichoderma koningii, Trichoderma sp. and Phoma herbarum were assessed in the presence of hydrocarbons...
  82. ncbi Isolation of a Delta5-fatty acid desaturase gene from Mortierella alpina
    L V Michaelson
    School of Biological Sciences, University of Bristol, Woodland Road, Bristol BS8 1UG, United Kingdom
    J Biol Chem 273:19055-9. 1998
    ..be a precursor of the prostaglandins and the leukotrienes but it is also accumulated by the filamentous fungus Mortierella alpina. We have isolated a cDNA encoding the Delta5-fatty acid desaturase from M...
  83. ncbi Propionic acid production by cofermentation of Lactobacillus buchneri and Lactobacillus diolivorans in sourdough
    Chonggang Zhang
    Department of Agricultural, Food and Nutritional Science, 4 10 Agriculture Forestry Centre, University of Alberta, Edmonton, AB, Canada
    Food Microbiol 27:390-5. 2010
    ..Bread slices were inoculated with Aspergillus clavatus, Cladosporium spp., Mortierella spp. or Penicillium roquefortii...
  84. ncbi Diversity in soil fungi from undisturbed and disturbed Celtis tala and Scutia buxifolia forests in the eastern Buenos Aires province (Argentina)
    Marta Cabello
    Instituto Spegazzini, Universidad Nacional de La Plata, Argentina
    Microbiol Res 157:115-25. 2002
    ..oxysporum, Gliocladium roseum, Humicola fusco-atra, Mortierella sp...
  85. ncbi A second functional delta5 fatty acid desaturase in the cellular slime mould Dictyostelium discoideum
    T Saito
    Division of Biological Sciences, Graduate School of Science, Hokkaido University, Sapporo, Japan
    Eur J Biochem 267:1813-8. 2000
    ..The whole sequence was 42% identical to the Delta5 desaturase of Mortierella alpina. This desaturase is a novel member of the cytochrome b5-containing Delta5 fatty acid desaturase...
  86. ncbi Microbial models of mammalian metabolism. Fungal metabolism of phenolic and nonphenolic p-cymene-related drugs and prodrugs. I. Metabolites of thymoxamine
    C Moussa
    Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, URA 400 CNRS, Universite Rene Descartes, Paris, France
    Drug Metab Dispos 25:301-10. 1997
    ..3 and desacetylthymoxamine-O-sulfate 6, were produced from DAT by Mucor rouxii and Mortierella isabellina. DAT-N-oxide 5, a putative animal microsomal metabolite, was also produced by M...
  87. ncbi Interactions between statins and Penicillium chrysogenum antifungal protein (PAF) to inhibit the germination of sporangiospores of different sensitive Zygomycetes
    Laszlo Galgoczy
    Department of Microbiology, Faculty of Sciences, University of Szeged, Szeged, Hungary
    FEMS Microbiol Lett 270:109-15. 2007
    ..In the present work, four species (Rhizopus stolonifer, Mortierella wolfii, Syncephalastrum racemosum and Mycotypha africana) that exhibited different sensitivities to lovastatin ..
  88. ncbi Oribatid mite (Acari, Oribatida) feeding on ectomycorrhizal fungi
    Katja Schneider
    Institute of Zoology, Darmstadt University of Technology, Darmstadt, Germany
    Mycorrhiza 16:67-72. 2005
    ..Fayod, Alternaria alternata (Fr.) Keissl. and Mortierella ramanniana (A. Møller) Linnem...
  89. pmc cDNA cloning and characterization of human Delta5-desaturase involved in the biosynthesis of arachidonic acid
    A E Leonard
    Department of Strategic Discovery Research, Ross Products Division, Abbott Laboratories, 3300 Stelzer Road, Columbus, OH 43219, USA
    Biochem J 347:719-24. 2000
    ..tag (EST) cDNA sequences with identity with Delta(5)- and Delta(6)-desaturases from a filamentous fungus, Mortierella alpina, were identified from the LifeSeq(R) database of Incyte Pharmaceuticals, Inc. (Palo Alto, CA, U.S.A.)...
  90. ncbi Sokodosides, steroid glycosides with an isopropyl side chain, from the marine sponge Erylus placenta
    Yumika Okada
    Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo ku, Tokyo 113 8657, Japan
    J Org Chem 71:4884-8. 2006
    ....
  91. pmc Phylogenomic analyses predict sistergroup relationship of nucleariids and fungi and paraphyly of zygomycetes with significant support
    Yu Liu
    Robert Cedergren Centre, Departement de Biochimie, Universite de Montreal, Montreal, Quebec, Canada
    BMC Evol Biol 9:272. 2009
    ..Yet, published phylogenies with up to five genes are without compelling statistical support, and genome-level data should be used to resolve this question with confidence...
  92. ncbi The DGA1 gene determines a second triglyceride synthetic pathway in yeast
    Peter Oelkers
    Institute of Human Nutrition and the Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Biol Chem 277:8877-81. 2002
    ..Recent studies of an oleaginous fungus, Mortierella ramanniana, identified a new family of enzymes with in vitro acyl-CoA:diacylglycerol acyltransferase activity...
  93. ncbi Effects of arachidonate-enriched triacylglycerol supplementation on serum fatty acids and platelet aggregation in healthy male subjects with a fish diet
    Aki Kusumoto
    Institute for Health Care Science, Suntory Ltd, 1 1 1 Wakayamadai, Shimamoto cho, Mishima gun, Osaka 618 8503, Japan
    Br J Nutr 98:626-35. 2007
    ..TAG ingested was an edible oil, extracted and purified from a biomass of submerged fermented Mortierella alpina. Mean daily intake of fish and shellfish by subjects was 87.2 (se5...
  94. ncbi [Allelopathy of Phragmites australis on Spartina alterniflora under different salinity]
    Kun Zheng
    School of Life Science, Nanjing University, Nanjing, China
    Ying Yong Sheng Tai Xue Bao 20:1863-7. 2009
    ..and 25% were used to treat the seeds and seedlings of Spartina alterniflora and the endemic beneficial fungi (Mortierella sp.) of S...
  95. ncbi Purification and characterization of diacylglycerol acyltransferase from the lipid body fraction of an oleaginous fungus
    Y Kamisaka
    Applied Microbiology Department, National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki
    J Biochem 121:1107-14. 1997
    ..3.1.20] was purified to apparent homogeneity from the lipid body fraction of an oleaginous fungus, Mortierella ramanniana var. angulispora. The enzyme was solubilized from the lipid body fraction with 0...
  96. ncbi [Progress in production of arachidonic acid by Mortierella alpina and genetic modification]
    Leilei Cong
    State Key Laboratory of Materials Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing 210009, China
    Sheng Wu Gong Cheng Xue Bao 26:1232-8. 2010
    ..In recent years, arachidonic acid production by Mortierella alpina is becoming a research highlight...
  97. ncbi [Biomass carbohydrates assimilation and lipid accumulation by Mortierella isabellina]
    Dahui Xing
    School of Chemistry and Life Science, Changchun University of Technology, Changchun, China
    Sheng Wu Gong Cheng Xue Bao 26:189-93. 2010
    Biomass carbohydrates assimilation and lipid accumulation by Mortierella isabellina M2 strain were investigated. Corn fiber hydrolysate was specially studied. The results showed M...
  98. ncbi Advances in the production of various polyunsaturated fatty acids through Oleaginous Fungus Mortierella alpina breeding
    Eiji Sakuradani
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan
    Biosci Biotechnol Biochem 74:908-17. 2010
    ..The filamentous fungus Mortierella alpina 1S-4 produces triacylglycerols rich in arachidonic acid, i.e...
  99. ncbi Two new antimicrobial lysoplasmanylinositols from the marine sponge Theonella swinhoei
    S Matsunaga
    Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan
    J Nat Prod 64:816-8. 2001
    ..Two new antimicrobial lysoplasmanylinositols have been isolated from the marine sponge Theonella swinhoei. Their structures were elucidated on the basis of spectroscopic and chemical analysis...
  100. ncbi Identification of Delta5-fatty acid desaturase from the cellular slime mold dictyostelium discoideum
    T Saito
    Division of Biological Sciences, Graduate School of Science, Hokkaido University, Sapporo, Japan
    Eur J Biochem 265:809-14. 1999
    ..The whole sequence was 38.6% identical to the initially identified Delta5-desaturase of Mortierella alpina. We have confirmed its function as Delta5-desaturase by over expression mutation in D...
  101. pmc Expression of Umbelopsis ramanniana DGAT2A in seed increases oil in soybean
    Kathryn Lardizabal
    Calgene Campus, Monsanto Company, Davis, California 95616, USA
    Plant Physiol 148:89-96. 2008
    ..a codon-optimized version of a diacylglycerol acyltransferase 2A from the soil fungus Umbelopsis (formerly Mortierella) ramanniana in soybean seed during development, resulting in an absolute increase in oil of 1...

Research Grants1

  1. Enzyme Targets-Sterol Synthesis-Opportunistic Pathogens
    WILLIAM NES; Fiscal Year: 2004
    ..The results from these studies will facilitate the design of therapeutic strategies aimed to provide species-specific discrimination of inhibition in the ergosterol biosynthetic pathway. ..