sinorhizobium meliloti

Summary

Summary: A species of gram-negative, aerobic bacteria that causes formation of root nodules on some, but not all, types of sweet clover, MEDICAGO SATIVA, and fenugreek.

Top Publications

  1. pmc How rhizobial symbionts invade plants: the Sinorhizobium-Medicago model
    Kathryn M Jones
    Department of Biology, Massachusetts Institute of Technology, Building 68, Room 633, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
    Nat Rev Microbiol 5:619-33. 2007
  2. pmc A genome-wide survey of sRNAs in the symbiotic nitrogen-fixing alpha-proteobacterium Sinorhizobium meliloti
    Jan Philip Schlüter
    Institute of Biology III, Faculty of Biology, University of Freiburg, Freiburg, Germany
    BMC Genomics 11:245. 2010
  3. ncbi A gene expression atlas of the model legume Medicago truncatula
    Vagner A Benedito
    Samuel Roberts Noble Foundation, 2510 Sam Noble Parkway, Ardmore, OK 73401, USA
    Plant J 55:504-13. 2008
  4. ncbi Plant peptides govern terminal differentiation of bacteria in symbiosis
    Willem Van de Velde
    Institut des Sciences du Vegetal, Centre National de la Recherche Scientifique, 91198 Gif sur Yvette Cedex, France
    Science 327:1122-6. 2010
  5. ncbi The genome of the natural genetic engineer Agrobacterium tumefaciens C58
    D W Wood
    Department of Microbiology, University of Washington, 1959 NE Pacific Street, Box 357242, Seattle, WA 98195, USA
    Science 294:2317-23. 2001
  6. pmc A remorin protein interacts with symbiotic receptors and regulates bacterial infection
    Benoit Lefebvre
    Laboratoire des Interactions Plantes Micro organismes, Institut National de la Recherche Agronomique, Centre National de la Recherche Scientifique, 31326 Castanet Tolosan Cedex, France
    Proc Natl Acad Sci U S A 107:2343-8. 2010
  7. pmc A highly conserved protein of unknown function in Sinorhizobium meliloti affects sRNA regulation similar to Hfq
    Shree P Pandey
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 4307, USA
    Nucleic Acids Res 39:4691-708. 2011
  8. pmc Proteomic alterations explain phenotypic changes in Sinorhizobium meliloti lacking the RNA chaperone Hfq
    Lise Barra-Bily
    Interactions Cellulaires et Moleculaires, DUALS, CNRS UMR 6026, Universite de Rennes I, Campus de Beaulieu, 35042 Rennes Cedex, France
    J Bacteriol 192:1719-29. 2010
  9. ncbi Global transcriptional analysis of the phosphate starvation response in Sinorhizobium meliloti strains 1021 and 2011
    E Krol
    Lehrstuhl fur Genetik, Fakultat fur Biologie, Universitat Bielefeld, Postfach 100131, 33501, Bielefeld, Germany
    Mol Genet Genomics 272:1-17. 2004
  10. pmc The Sinorhizobium meliloti RNA chaperone Hfq influences central carbon metabolism and the symbiotic interaction with alfalfa
    Omar Torres-Quesada
    Grupo de Ecología Genética de la Rizosfera, Estacion Experimental del Zaidin, CSIC, Profesor Albareda, 1, 18008 Granada, Spain
    BMC Microbiol 10:71. 2010

Detail Information

Publications266 found, 100 shown here

  1. pmc How rhizobial symbionts invade plants: the Sinorhizobium-Medicago model
    Kathryn M Jones
    Department of Biology, Massachusetts Institute of Technology, Building 68, Room 633, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
    Nat Rev Microbiol 5:619-33. 2007
    ..we review recent discoveries about the mutual recognition process that allows the model rhizobial symbiont Sinorhizobium meliloti to invade and differentiate inside its host plant alfalfa (Medicago sativa) and the model host plant ..
  2. pmc A genome-wide survey of sRNAs in the symbiotic nitrogen-fixing alpha-proteobacterium Sinorhizobium meliloti
    Jan Philip Schlüter
    Institute of Biology III, Faculty of Biology, University of Freiburg, Freiburg, Germany
    BMC Genomics 11:245. 2010
    ..This study reports on a comprehensive screen for sRNAs in the symbiotic nitrogen-fixing alpha-proteobacterium Sinorhizobium meliloti applying deep sequencing of cDNAs and microarray hybridizations.
  3. ncbi A gene expression atlas of the model legume Medicago truncatula
    Vagner A Benedito
    Samuel Roberts Noble Foundation, 2510 Sam Noble Parkway, Ardmore, OK 73401, USA
    Plant J 55:504-13. 2008
    ..The data presented here represent an unparalleled resource for legume functional genomics, which will accelerate discoveries in legume biology...
  4. ncbi Plant peptides govern terminal differentiation of bacteria in symbiosis
    Willem Van de Velde
    Institut des Sciences du Vegetal, Centre National de la Recherche Scientifique, 91198 Gif sur Yvette Cedex, France
    Science 327:1122-6. 2010
    ..Because NCRs resemble antimicrobial peptides, our findings reveal a previously unknown innovation of the host plant, which adopts effectors of the innate immune system for symbiosis to manipulate the cell fate of endosymbiotic bacteria...
  5. ncbi The genome of the natural genetic engineer Agrobacterium tumefaciens C58
    D W Wood
    Department of Microbiology, University of Washington, 1959 NE Pacific Street, Box 357242, Seattle, WA 98195, USA
    Science 294:2317-23. 2001
    ..tumefaciens and the plant symbiont Sinorhizobium meliloti suggest a recent evolutionary divergence...
  6. pmc A remorin protein interacts with symbiotic receptors and regulates bacterial infection
    Benoit Lefebvre
    Laboratoire des Interactions Plantes Micro organismes, Institut National de la Recherche Agronomique, Centre National de la Recherche Scientifique, 31326 Castanet Tolosan Cedex, France
    Proc Natl Acad Sci U S A 107:2343-8. 2010
    ..We used root nodule symbiosis between Medicago truncatula and Sinorhizobium meliloti to study the roles of a remorin that is specifically induced during nodulation...
  7. pmc A highly conserved protein of unknown function in Sinorhizobium meliloti affects sRNA regulation similar to Hfq
    Shree P Pandey
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 4307, USA
    Nucleic Acids Res 39:4691-708. 2011
    ..Indeed, eliminating SMc01113/YbeY expression in Sinorhizobium meliloti produces symbiotic and physiological phenotypes strikingly similar to those of the hfq mutant...
  8. pmc Proteomic alterations explain phenotypic changes in Sinorhizobium meliloti lacking the RNA chaperone Hfq
    Lise Barra-Bily
    Interactions Cellulaires et Moleculaires, DUALS, CNRS UMR 6026, Universite de Rennes I, Campus de Beaulieu, 35042 Rennes Cedex, France
    J Bacteriol 192:1719-29. 2010
    The ubiquitous bacterial RNA-binding protein Hfq is involved in stress resistance and pathogenicity. In Sinorhizobium meliloti, Hfq is essential for the establishment of symbiosis with Medicago sativa and for nitrogen fixation...
  9. ncbi Global transcriptional analysis of the phosphate starvation response in Sinorhizobium meliloti strains 1021 and 2011
    E Krol
    Lehrstuhl fur Genetik, Fakultat fur Biologie, Universitat Bielefeld, Postfach 100131, 33501, Bielefeld, Germany
    Mol Genet Genomics 272:1-17. 2004
    ..to phosphate starvation was analysed at the transcriptional level in two closely related strains of Sinorhizobium meliloti, Rm1021 and Rm2011...
  10. pmc The Sinorhizobium meliloti RNA chaperone Hfq influences central carbon metabolism and the symbiotic interaction with alfalfa
    Omar Torres-Quesada
    Grupo de Ecología Genética de la Rizosfera, Estacion Experimental del Zaidin, CSIC, Profesor Albareda, 1, 18008 Granada, Spain
    BMC Microbiol 10:71. 2010
    ..b>Sinorhizobium meliloti is a model soil bacterium known for its ability to establish a beneficial nitrogen-fixing intracellular ..
  11. pmc A novel family in Medicago truncatula consisting of more than 300 nodule-specific genes coding for small, secreted polypeptides with conserved cysteine motifs
    Peter Mergaert
    Institut des Sciences du Vegetal, Centre National de la Recherche Scientifique, Avenue de la Terrasse, 91198 Gif sur Yvette, France
    Plant Physiol 132:161-73. 2003
    ..Potential functions of the NCR polypeptides in cell-to-cell signaling and creation of a defense system are discussed...
  12. pmc Crystal structure of the flavoprotein ArsH from Sinorhizobium meliloti
    Jun Ye
    Department of Biochemistry and Molecular Biology, Wayne State University, School of Medicine, 540 East Canfield Avenue, Detroit, MI 48201, USA
    FEBS Lett 581:3996-4000. 2007
    Purified ArsH from Sinorhizobium meliloti exhibits NADPH:FMN-dependent reduction of molecular O2 to hydrogen peroxide and catalyzes reduction of azo dyes. The structure of ArsH was determined at 1.8A resolution...
  13. pmc Expression profiling in Medicago truncatula identifies more than 750 genes differentially expressed during nodulation, including many potential regulators of the symbiotic program
    Fikri El Yahyaoui
    Laboratoire des Interactions Plantes Micro organismes, Institut National de la Recherche Agronomique Centre National de la Recherche Scientifique, 31326 Castanet Tolosan Cedex, France
    Plant Physiol 136:3159-76. 2004
    ..the symbiotic interaction between the model legume Medicago truncatula and the nitrogen-fixing bacterium Sinorhizobium meliloti. Macro- and microarrays containing about 6,000 probes were generated on the basis of three cDNA libraries ..
  14. ncbi The composite genome of the legume symbiont Sinorhizobium meliloti
    F Galibert
    UMR6061-CNRS, , , , F-35043 Rennes Cedex, France
    Science 293:668-72. 2001
    ..We present here the annotated DNA sequence of the alpha-proteobacterium Sinorhizobium meliloti, the symbiont of alfalfa. The tripartite 6.7-megabase (Mb) genome comprises a 3.65-Mb chromosome, and 1...
  15. pmc The Medicago truncatula lysin [corrected] motif-receptor-like kinase gene family includes NFP and new nodule-expressed genes
    Jean Francois Arrighi
    Laboratoire des Interactions Plantes Microorganismes, Institut National de la Recherche Agronomique Centre National de la Recherche Scientifique, Unité Mixte de Recherche 441 2594, 31326 Castanet Tolosan, France
    Plant Physiol 142:265-79. 2006
    ..Most of the newly identified genes were found to be expressed in roots and nodules, suggesting this class of receptors may be more extensively involved in nodulation than was previously known...
  16. pmc Use of RmInt1, a group IIB intron lacking the intron-encoded protein endonuclease domain, in gene targeting
    Fernando M García-Rodríguez
    Grupo de Ecología Genética, Estacion Experimental del Zaidin, Consejo Superior de Investigaciones Científica, C Profesor Albareda 1, 18008 Granada, Spain
    Appl Environ Microbiol 77:854-61. 2011
    ..subclass IIB3/D intron with an IEP lacking D and En domains, is highly active in retrohoming in its host, Sinorhizobium meliloti. We found that RmInt1 was also mobile in E...
  17. pmc Auxin and nitric oxide control indeterminate nodule formation
    Youry Pii
    Dipartimento Scientifico Tecnologico, University of Verona, Verona, Italy
    BMC Plant Biol 7:21. 2007
    ..Both plants and rhizobia synthesise auxin. We have addressed the effects of bacterial auxin (IAA) on nodulation by using Sinorhizobium meliloti and Rhizobium leguminosarum bacteria genetically engineered for increased auxin synthesis.
  18. pmc Importance of trehalose biosynthesis for Sinorhizobium meliloti Osmotolerance and nodulation of Alfalfa roots
    Ana Domínguez-Ferreras
    Departamento de Microbiologia del Suelo y Sistemas Simbioticos, Estacion Experimental del Zaidin, CSIC, Granada, Spain
    J Bacteriol 191:7490-9. 2009
    ..In this study, we have investigated the role of endogenous trehalose synthesis in the osmotolerance of Sinorhizobium meliloti. Genes coding for three possible trehalose synthesis pathways are present in the genome of S...
  19. pmc Dual control of Sinorhizobium meliloti RpoE2 sigma factor activity by two PhyR-type two-component response regulators
    Bénédicte Bastiat
    Laboratoire des Interactions Plantes Microorganismes LIPM, UMR 441 2594 INRA CNRS BP52627, 31326 Castanet Tolosan Cedex, France
    J Bacteriol 192:2255-65. 2010
    RpoE2 is an extracytoplasmic function (ECF) sigma factor involved in the general stress response of Sinorhizobium meliloti, the nitrogen-fixing symbiont of the legume plant alfalfa...
  20. ncbi A nodule-specific protein secretory pathway required for nitrogen-fixing symbiosis
    Dong Wang
    Department of Biology, Stanford University, Stanford, CA 94305, USA
    Science 327:1126-9. 2010
    The nitrogen-fixing symbiosis between Sinorhizobium meliloti and its leguminous host plant Medicago truncatula occurs in a specialized root organ called the nodule...
  21. pmc The low-molecular-weight fraction of exopolysaccharide II from Sinorhizobium meliloti is a crucial determinant of biofilm formation
    Luciana V Rinaudi
    Departamento de Biologia Molecular, Universidad Nacional de Rio Cuarto, 5800 Rio Cuarto, Cordoba, Argentina
    J Bacteriol 191:7216-24. 2009
    b>Sinorhizobium meliloti is a soil bacterium that elicits the formation of root organs called nodules on its host plant, Medicago sativa...
  22. ncbi The Rhizobium meliloti putA gene: its role in the establishment of the symbiotic interaction with alfalfa
    J I Jimenez-Zurdo
    Departamento de Microbiologia del Suelo y Sistemas Simbioticos, Estacion Experimental del Zaidin, CSIC, Granada, Spain
    Mol Microbiol 23:85-93. 1997
    ..Furthermore, we show that the PutA- phenotype leads to a significant reduction of alfalfa root colonization by R. meliloti...
  23. pmc (Homo)glutathione depletion modulates host gene expression during the symbiotic interaction between Medicago truncatula and Sinorhizobium meliloti
    Chiara Pucciariello
    Interactions Biotiques et Santé Végétale, Unite Mixte de Recherche, Institut National de la Recherche Agronomique 1301, Centre National de la Recherche Scientifique 6243, Universite de Nice Sophia Antipolis, 06903 Sophia Antipolis Cedex, France
    Plant Physiol 151:1186-96. 2009
    ..truncatula. In this study, the plant transcriptomic response to Sinorhizobium meliloti infection under (h)GSH depletion was investigated using cDNA-amplified fragment length polymorphism ..
  24. pmc The role of sigma factor RpoH1 in the pH stress response of Sinorhizobium meliloti
    Daniella K C de Lucena
    Lehrstuhl fur Genetik, Fakultat fur Biologie, Universitat Bielefeld, Bielefeld, Germany
    BMC Microbiol 10:265. 2010
    ..The purpose of this study was to gain detailed insight into the participation of sigma factors in the complex stress response system of S. meliloti 1021 using pH stress as an effector...
  25. ncbi Sinorhizobium meliloti metabolism in the root nodule: a proteomic perspective
    Michael A Djordjevic
    Australian Research Council Centre of Excellence for Integrative Legume Research, Genomic Interactions Group, Research School of Biological Sciences, Australian National University, GPO Box 475, Canberra, ACT 2601, Australia
    Proteomics 4:1859-72. 2004
    The proteome of the model symbiotic bacterium, Sinorhizobium meliloti was examined to determine the enzymatic reactions and cell processes that occur when S. meliloti occupies the root nodules of Medicago truncatula and Melilotus alba...
  26. pmc Regulation and properties of PstSCAB, a high-affinity, high-velocity phosphate transport system of Sinorhizobium meliloti
    Ze Chun Yuan
    Center for Environmental Genomics, Department of Biology, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    J Bacteriol 188:1089-102. 2006
    The properties and regulation of the pstSCAB-encoded Pi uptake system from the alfalfa symbiont Sinorhizobium meliloti are reported...
  27. pmc Functional characterization of the Sinorhizobium meliloti acetate metabolism genes aceA, SMc00767, and glcB
    J A Ramírez-Trujillo
    Departamento de Microbiologia Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Av Universidad 2001, Cuernavaca, Morelos 62210, Mexico
    J Bacteriol 189:5875-84. 2007
    ..open reading frame (SMc00767) located downstream of aceA were isolated and functionally characterized in Sinorhizobium meliloti. Independent and double interposon mutants of each gene were constructed, and the corresponding phenotypes ..
  28. ncbi The model legume Medicago truncatula A17 is poorly matched for N2 fixation with the sequenced microsymbiont Sinorhizobium meliloti 1021
    Jason J Terpolilli
    Centre for Rhizobium Studies, School of Biological Sciences and Biotechnology, Murdoch University, South St, Murdoch, WA 6150, Australia
    New Phytol 179:62-6. 2008
    ..is currently being sequenced as a model legume, complementing the sequenced root nodule bacterial strain Sinorhizobium meliloti 1021 (Sm1021). In this study, the effectiveness of the Sm1021-M...
  29. pmc Proteomic analysis of wild-type Sinorhizobium meliloti responses to N-acyl homoserine lactone quorum-sensing signals and the transition to stationary phase
    Hancai Chen
    Genomic Interactions Group, Research School for Biological Sciences, Australian National University, Canberra, Australia
    J Bacteriol 185:5029-36. 2003
    Proteome analysis revealed that two long-chain N-acyl homoserine lactones (AHLs) produced by Sinorhizobium meliloti 1021 induced significant differences in the accumulation of more than 100 polypeptides in early-log-phase cultures of the ..
  30. ncbi ppGpp in Sinorhizobium meliloti: biosynthesis in response to sudden nutritional downshifts and modulation of the transcriptome
    Elizaveta Krol
    Faculty of Biology and Center for Systems Biology, University of Freiburg, Schänzlestr 1, 79104 Freiburg, Germany
    Mol Microbiol 81:1233-54. 2011
    b>Sinorhizobium meliloti Rm2011 responds to sudden shifts to nitrogen or carbon starvation conditions by an accumulation of the stringent response alarmone ppGpp and remodelling of the transcriptome...
  31. pmc Quorum sensing controls exopolysaccharide production in Sinorhizobium meliloti
    Melanie M Marketon
    Department of Molecular and Cell Biology, University of Texas at Dallas, Richardson, TX 75083 0688, USA
    J Bacteriol 185:325-31. 2003
    b>Sinorhizobium meliloti is a soil bacterium capable of invading and establishing a symbiotic relationship with alfalfa plants. This invasion process requires the synthesis, by S...
  32. pmc EFD Is an ERF transcription factor involved in the control of nodule number and differentiation in Medicago truncatula
    Tatiana Vernié
    Laboratoire des Interactions Plantes Micro organismes, Unite Mixte de Recherche, Centre National de la Recherche Scientifique Institut National de la Recherche Agronomique 2594 441, F 31320 Castanet Tolosan, France
    Plant Cell 20:2696-713. 2008
    ..Our work thus reveals a key regulator linking early and late stages of nodulation and suggests that the regulation of the cytokinin pathway is important both for nodule initiation and development...
  33. ncbi Investigations of Rhizobium biofilm formation
    Nancy A Fujishige
    Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, USA
    FEMS Microbiol Ecol 56:195-206. 2006
    ..We developed conditions for analyzing the ability of two fast-growing rhizobia, Sinorhizobium meliloti and Rhizobium leguminosarum bv...
  34. pmc Mapping the Sinorhizobium meliloti 1021 solute-binding protein-dependent transportome
    T H Mauchline
    School of Biological Sciences, University of Reading, Reading RG6 6AJ, United Kingdom
    Proc Natl Acad Sci U S A 103:17933-8. 2006
    ..to nearly all ATP-binding cassette (ABC) and tripartite ATP-independent periplasmic (TRAP) transporters of Sinorhizobium meliloti. In total, specific inducers were identified for 76 transport systems, amounting to approximately 47% of ..
  35. pmc Sinorhizobium meliloti, a bacterium lacking the autoinducer-2 (AI-2) synthase, responds to AI-2 supplied by other bacteria
    Catarina S Pereira
    Bacterial Signaling Laboratory, Instituto Gulbenkian de Ciencia, Oeiras, Portugal
    Mol Microbiol 70:1223-35. 2008
    ..Here, we show that Sinorhizobium meliloti, a plant symbiont lacking the gene for the AI-2 synthase, while not capable of producing AI-2 can ..
  36. ncbi Role of the Sinorhizobium meliloti global regulator Hfq in gene regulation and symbiosis
    Mengsheng Gao
    Soil and Water Science Department, Cancer and Genetics Research Complex, Room 330E, University of Florida Institute of Food and Agricultural Sciences, Gainesville 32610, USA
    Mol Plant Microbe Interact 23:355-65. 2010
    ..To begin understanding the role of Hfq in the Sinorhizobium meliloti-Medicago truncatula nitrogen-fixing symbiosis, we defined free-living and symbiotic phenotypes of an hfq ..
  37. pmc The response of carbon metabolism and antioxidant defenses of alfalfa nodules to drought stress and to the subsequent recovery of plants
    Loreto Naya
    Departamento de Nutrición Vegetal, Estacion Experimental de Aula Dei, Consejo Superior de Investigaciones Cientificas, 50080 Zaragoza, Spain
    Plant Physiol 144:1104-14. 2007
    ..We conclude that a limitation in metabolic capacity of bacteroids and oxidative damage of cellular components are contributing factors to the inhibition of N(2)ase activity in alfalfa nodules...
  38. pmc Transcription reprogramming during root nodule development in Medicago truncatula
    Sandra Moreau
    Laboratoire des Interactions Plantes Micro organismes, Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, Castanet Tolosan, France
    PLoS ONE 6:e16463. 2011
    ..have been used to study the transcriptome of root nodules induced by either wild type or mutant strains of Sinorhizobium meliloti. In this way we have defined eight major activation patterns in nodules and identified associated ..
  39. pmc Nitrogen fixation mutants of Medicago truncatula fail to support plant and bacterial symbiotic gene expression
    Colby G Starker
    Department of Biological Sciences, Stanford University, Stanford, California 94305, USA
    Plant Physiol 140:671-80. 2006
    ..To monitor bacterial status in mutant nodules, we assayed Sinorhizobium meliloti symbiosis gene promoters (nodF, exoY, bacA, and nifH) in the defective in nitrogen fixation mutants...
  40. ncbi Sinorhizobium meliloti differentiation during symbiosis with alfalfa: a transcriptomic dissection
    Delphine Capela
    Laboratoire des Interactions Plantes Microorganismes, UMR INRA CNRS 441 2594, BP52627, 31326 Castanet Tolosan, France
    Mol Plant Microbe Interact 19:363-72. 2006
    b>Sinorhizobium meliloti is a soil bacterium able to induce the formation of nodules on the root of specific legumes, including alfalfa (Medicago sativa)...
  41. ncbi Agrobacterium rhizogenes-transformed roots of Medicago truncatula for the study of nitrogen-fixing and endomycorrhizal symbiotic associations
    A Boisson-Dernier
    , INRA-CNRS UMR215, Castanet-Tolosan, France
    Mol Plant Microbe Interact 14:695-700. 2001
    ..morphology to normal roots and can be nodulated successfully by their nitrogen-fixing symbiotic partner, Sinorhizobium meliloti. Furthermore, spatiotemporal expression of the Nod factor-responsive reporter pMtENOD11-gusA in hairy root ..
  42. pmc Analysis of infection thread development using Gfp- and DsRed-expressing Sinorhizobium meliloti
    Daniel J Gage
    Department of Molecular and Cell Biology, University of Connecticut, Storrs 06269, USA
    J Bacteriol 184:7042-6. 2002
    b>Sinorhizobium meliloti growth inside infection threads was monitored after inoculation of alfalfa with red- or green-tagged bacteria. Most threads were populated with single bacterial types...
  43. ncbi Extension of the Rhizobium meliloti succinoglycan biosynthesis gene cluster: identification of the exsA gene encoding an ABC transporter protein, and the exsB gene which probably codes for a regulator of succinoglycan biosynthesis
    A Becker
    Lehrstuhl fur Genetik, Fakultat fur Biologie, Universitat Bielefeld, Federal Republic of Germany
    Mol Gen Genet 249:487-97. 1995
    ..It was demonstrated that this influence is not due to transcriptional regulation of the exo genes by the exsB gene product. By plasmid integration it was shown that exsA and exsB represent monocistronic transcription units...
  44. pmc sinI- and expR-dependent quorum sensing in Sinorhizobium meliloti
    Mengsheng Gao
    Department of Horticulture and Crop Science, Ohio State University, Columbus, 43210, USA
    J Bacteriol 187:7931-44. 2005
    Quorum sensing (QS) in Sinorhizobium meliloti, the N-fixing bacterial symbiont of Medicago host plants, involves at least half a dozen different N-acyl homoserine lactone (AHL) signals and perhaps an equal number of AHL receptors...
  45. pmc The twin arginine transport system appears to be essential for viability in Sinorhizobium meliloti
    Brad S Pickering
    Department of Microbiology, University of Manitoba, Winnipeg, Manitoba R3T 2N2, Canada
    J Bacteriol 192:5173-80. 2010
    ..Since the annotation of Sinorhizobium meliloti Rm1021 genome suggests that there may be up to 94 putative Tat substrates, we hypothesized that ..
  46. pmc Sinorhizobium meliloti plasmid pRm1132f replicates by a rolling-circle mechanism
    L R Barran
    Soils and Crops Research and Development Centre, Agriculture and Agri Food Canada, Sainte Foy, Quebec G1V 2J3, Canada
    J Bacteriol 183:2704-8. 2001
    pRm1132f isolated from Sinorhizobium meliloti is a group III rolling-circle-replicating (RCR) plasmid. At least seven of eight open reading frames in the nucleotide sequence represented coding regions...
  47. ncbi Cell cycle regulation in the course of nodule organogenesis in Medicago
    F Foucher
    , UPR40, Centre National de la Recherche Scientifique, Gif sur Yvette, France
    Plant Mol Biol 43:773-86. 2000
    ..This review summarizes the present knowledge on cell cycle reactivation and meristem formation in response to Nod factors and reports on a novel plant cell cycle regulator that can switch mitotic cycles to differentiation programmes...
  48. pmc Population genomics of the facultatively mutualistic bacteria Sinorhizobium meliloti and S. medicae
    Brendan Epstein
    Department of Plant Biology, University of Minnesota, St Paul, Minnesota, United States of America
    PLoS Genet 8:e1002868. 2012
    ..Based upon available functional information, several genes identified as targets of selection are likely to alter the symbiosis with the host plant, making them attractive targets for further functional characterization...
  49. pmc Sinorhizobium meliloti ExoR is the target of periplasmic proteolysis
    Hai Yang Lu
    Biological Sciences Department, Lehman College, The City University of New York, Bronx, New York, USA
    J Bacteriol 194:4029-40. 2012
    b>Sinorhizobium meliloti ExoR regulates the production of succinoglycan and flagella through the ExoS/ChvI two-component regulatory system. ExoR has been proposed to inhibit the ExoS sensor through direct interaction in the periplasm...
  50. ncbi EPS II-dependent autoaggregation of Sinorhizobium meliloti planktonic cells
    Fernando G Sorroche
    Departamento de Biologia Molecular, Universidad Nacional de Rio Cuarto, Rio Cuarto, Cordoba, Argentina
    Curr Microbiol 61:465-70. 2010
    Planktonic cells of Sinorhizobium meliloti, a Gram-negative symbiotic bacterium, display autoaggregation under static conditions. ExpR is a LuxR-type regulator that controls many functions in S...
  51. pmc Multiple genetic controls on Rhizobium meliloti syrA, a regulator of exopolysaccharide abundance
    M J Barnett
    Department of Biological Sciences, Stanford University, California 94305, USA
    Genetics 148:19-32. 1998
    ..Instead, expression of the nitrogen fixation (nifHDKE) genes upstream of syrA plays a role. Specific and distinct sets of genetic controls may operate at different times during nodule invasion...
  52. pmc Six nonnodulating plant mutants defective for Nod factor-induced transcriptional changes associated with the legume-rhizobia symbiosis
    Raka M Mitra
    Department of Biological Sciences, 371 Serra Mall, Stanford University, CA 94305 5020, USA
    Proc Natl Acad Sci U S A 101:10217-22. 2004
    ..We identified 46 sequences that are differentially expressed in plants exposed for 24 h to WT Sinorhizobium meliloti or to the invasion defective S. meliloti mutant, exoA...
  53. ncbi MotE serves as a new chaperone specific for the periplasmic motility protein, MotC, in Sinorhizobium meliloti
    Elke Eggenhofer
    Lehrstuhl fur Genetik, Universitat Regensburg, D 93040 Regensburg, Germany
    Mol Microbiol 52:701-12. 2004
    The flagella of Sinorhizobium meliloti rotate solely clockwise and vary their rotary speed to provoke changes in the swimming path...
  54. pmc Nitric oxide is required for an optimal establishment of the Medicago truncatula-Sinorhizobium meliloti symbiosis
    Jennifer Del Giudice
    UMR INRA 1301 CNRS 6243 Université de Nice Sophia Antipolis, Interactions Biotiques et Santé Végétale, Institut Agrobiotech, 400 Route des Chappes, Sophia Antipolis Cedex, France
    New Phytol 191:405-17. 2011
    ..we detected NO production in the first steps, during infection threads growth, of the Medicago truncatula-Sinorhizobium meliloti symbiotic interaction. Nitric oxide was also detected, by confocal microscopy, in nodule primordia...
  55. ncbi Nitric oxide is formed in Medicago truncatula-Sinorhizobium meliloti functional nodules
    Emmanuel Baudouin
    Interactions Plantes Microorganismes et Santé Végétale, UMR INRA 1064 Université de Nice Sophia Antipolis CNRS 6192, 400, Route des Chappes, BP 167, 06903 Sophia Antipolis, France
    Mol Plant Microbe Interact 19:970-5. 2006
    ..Here, we defined when and where NO is produced during Medicago truncatula-Sinorhizobium meliloti symbiosis...
  56. ncbi Evidences of autoregulation of hfq expression in Sinorhizobium meliloti strain 2011
    Patricio Sobrero
    Programa Interacciones Biológicas, Departamento de Ciencia y Tecnologia, Universidad Nacional de Quilmes, Bernal, Buenos Aires, Argentina
    Arch Microbiol 193:629-39. 2011
    ..In the α-proteobacterium Sinorhizobium meliloti, the large number of detected small RNA transcripts and the pleiotropic effects of hfq mutations lead to ..
  57. ncbi Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110
    Takakazu Kaneko
    Kazusa DNA Research Institute, 2 6 7 Kazusa Kamatari, Kisarazu, Chiba 292 0812, Japan
    DNA Res 9:189-97. 2002
    ..japonicum genes showed significant sequence similarity to those of both Mesorhizobium loti and Sinorhizobium meliloti, while 23% were unique to this species...
  58. ncbi Similarity between the Rhizobium meliloti fliP gene and pathogenicity-associated genes from animal and plant pathogens
    T M Finan
    Department of Biology, McMaster University, Hamilton, Ontario, Canada
    Gene 152:65-7. 1995
    ..It is likely that all of these proteins share a common functional role in the secretion of specific proteins from bacterial cells...
  59. pmc Contribution of NFP LysM domains to the recognition of Nod factors during the Medicago truncatula/Sinorhizobium meliloti symbiosis
    Sandra Bensmihen
    Laboratoire des Interactions Plantes Microorganismes, Institut National de la Recherche Agronomique, Castanet Tolosan, France
    PLoS ONE 6:e26114. 2011
    ..Nod factor perception (NFP) in the recognition of different substitutions of NFs produced by its symbiont Sinorhizobium meliloti. These substitutions are a sulphate group at the reducing end, which is essential for host specificity, ..
  60. pmc A survey of sRNA families in α-proteobacteria
    Coral Del Val
    CITIC UGR, Centro de Investigación en Tecnologías de la Información y de las Comunicaciones de la Universidad de Granada, Granada, Spain
    RNA Biol 9:119-29. 2012
    ..meliloti 1021. The distribution patterns of these sRNA families suggest major contributions of vertical inheritance and extensive ancestral duplication events to the evolution of sRNAs in plant-interacting bacteria...
  61. pmc Pharmacological evidence that multiple phospholipid signaling pathways link Rhizobium nodulation factor perception in Medicago truncatula root hairs to intracellular responses, including Ca2+ spiking and specific ENOD gene expression
    Dorothée Charron
    Laboratoire des Interactions Plantes Microorganismes, Unite Mixte de Recherche, Institut National de la Recherche Agronomique Centre National de la Recherche Scientifique, 31326 Castanet Tolosan, France
    Plant Physiol 136:3582-93. 2004
    ....
  62. pmc GlnB/GlnK PII proteins and regulation of the Sinorhizobium meliloti Rm1021 nitrogen stress response and symbiotic function
    Svetlana N Yurgel
    Institute of Biological Chemistry, Washington State University, Pullman, WA 99164 6340, USA
    J Bacteriol 192:2473-81. 2010
    The Sinorhizobium meliloti Rm1021 Delta glnD-sm2 mutant, which is predicted to make a GlnD nitrogen sensor protein truncated at its amino terminus, fixes nitrogen in symbiosis with alfalfa, but the plants cannot use this nitrogen for ..
  63. pmc glnD and mviN are genes of an essential operon in Sinorhizobium meliloti
    P A Rudnick
    Laboratoire de Biologie Moleculaire des relations Plantes Microorganismes, INRA CNRS, 31326 Castanet Tolosan Cedex, France
    J Bacteriol 183:2682-5. 2001
    To evaluate the role of uridylyl-transferase, the Sinorhizobium meliloti glnD gene was isolated by heterologous complementation in Azotobacter vinelandii. The glnD gene is cotranscribed with a gene homologous to Salmonella mviN...
  64. ncbi Resuscitation of viable but not culturable Sinorhizobium meliloti 41 pRP4-luc: effects of oxygen and host plant
    Marina Basaglia
    Dipartimento di Biotecnologie Agrarie, Agripolis Università di Padova, Viale dell Universita 16, 35020 Legnaro, Padova, Italy
    Curr Microbiol 54:167-74. 2007
    A plasmid-borne, firefly-derived, luciferase gene (luc) was inserted and stably inherited in Sinorhizobium meliloti 41 as a reporter gene. The strain obtained, S...
  65. pmc CbrA is a stationary-phase regulator of cell surface physiology and legume symbiosis in Sinorhizobium meliloti
    Katherine E Gibson
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    J Bacteriol 188:4508-21. 2006
    b>Sinorhizobium meliloti produces an exopolysaccharide called succinoglycan that plays a critical role in promoting symbiosis with its host legume, alfalfa (Medicago sativa)...
  66. pmc A mutant GlnD nitrogen sensor protein leads to a nitrogen-fixing but ineffective Sinorhizobium meliloti symbiosis with alfalfa
    Svetlana N Yurgel
    Institute of Biological Chemistry and School of Molecular Biosciences, Washington State University, Pullman, WA 99164 6340, USA
    Proc Natl Acad Sci U S A 105:18958-63. 2008
    ..In the symbiosis between Sinorhizobium meliloti and alfalfa, mutations in GlnD, the major bacterial nitrogen stress response sensor protein, led to a ..
  67. pmc L-Canavanine made by Medicago sativa interferes with quorum sensing in Sinorhizobium meliloti
    Neela D Keshavan
    Department of Molecular and Cell Biology, University of Texas at Dallas, FO 3 1, Richardson, TX 75083 0688, USA
    J Bacteriol 187:8427-36. 2005
    b>Sinorhizobium meliloti is a gram-negative soil bacterium, capable of establishing a nitrogen-fixing symbiosis with its legume host, alfalfa (Medicago sativa)...
  68. ncbi Identification of a hydroxyproline transport system in the legume endosymbiont Sinorhizobium meliloti
    Allyson M MacLean
    Center for Environmental Genomics, Department of Biology, McMaster University, Hamilton, Ontario, Canada
    Mol Plant Microbe Interact 22:1116-27. 2009
    ..an ABC-type transport system dedicated to the uptake of hydroxyproline in the legume endosymbiont Sinorhizobium meliloti. We have designated genes involved in hydroxyproline metabolism as hyp genes and show that an S...
  69. pmc Complex regulation of symbiotic functions is coordinated by MucR and quorum sensing in Sinorhizobium meliloti
    Konrad Mueller
    Department of Molecular and Cell Biology, University of Texas at Dallas, Richardson, TX 75080 0688, USA
    J Bacteriol 193:485-96. 2011
    In Sinorhizobium meliloti, the production of exopolysaccharides such as succinoglycan and exopolysaccharide II (EPS II) enables the bacterium to invade root nodules on Medicago sativa and establish a nitrogen-fixing symbiosis...
  70. pmc pSymA-dependent mobilization of the Sinorhizobium meliloti pSymB megaplasmid
    Helena Blanca-Ordóñez
    Plant Bacteria Interactions Laboratory, Departamento Microbiología del Suelo y Sistemas Simbióticos, Estacion Experimental del Zaidin, Consejo Superior de Investigaciones Cientificas CSIC, Profesor Albareda 1, Granada, Spain
    J Bacteriol 192:6309-12. 2010
    b>Sinorhizobium meliloti 1021 carries two megaplasmids, pSymA of 1,354 kb and pSymB of 1,683 kb, which are essential in establishing symbiosis with its legume hosts and important for bacterial fitness in the rhizosphere...
  71. ncbi Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states
    Christine Oswald
    Institute of Biochemistry, Heinrich Heine University Duesseldorf, Universitaetsstrasse 1, 40225 Duesseldorf, Germany
    J Biol Chem 283:32848-59. 2008
    The ATP-binding cassette transporter ChoVWX is one of several choline import systems operating in Sinorhizobium meliloti. Here fluorescence-based ligand binding assays were used to quantitate substrate binding by the periplasmic ligand-..
  72. pmc Formate-dependent autotrophic growth in Sinorhizobium meliloti
    Brad S Pickering
    Department of Microbiology, University if Manitoba, Winnipeg, MB, R3T 2N2, Canada
    J Bacteriol 190:6409-18. 2008
    ..Taken together, the data allow us to present a model of how S. meliloti can grow on defined medium containing only formate and bicarbonate as carbon sources...
  73. ncbi LysM domains of Medicago truncatula NFP protein involved in Nod factor perception. Glycosylation state, molecular modeling and docking of chitooligosaccharides and Nod factors
    Lonneke Mulder
    Centre de Recherches sur les Macromolecules Vegetales, CNRS affiliated with Université Joseph Fourier, 601 rue de la Chimie, BP 53, 38041 Grenoble Cedex 9, France
    Glycobiology 16:801-9. 2006
    ..In Medicago truncatula, specific recognition of Sinorhizobium meliloti and its Nod factors requires the NFP (Nod factor perception) gene, which encodes a putative serine/..
  74. ncbi Genome variation in the symbiotic nitrogen-fixing bacterium Sinorhizobium meliloti
    Hong Guo
    Center for Environmental Genomics, Department of Biology, McMaster University, Hamilton, ON L8S 4K1, Canada
    Genome 52:862-75. 2009
    ..the patterns of genome variation among 10 natural strains of the symbiotic nitrogen-fixing bacterium Sinorhizobium meliloti, using pulse field gel electrophoresis (PFGE) and whole-genome microarray hybridizations...
  75. pmc Ectoine-induced proteins in Sinorhizobium meliloti include an Ectoine ABC-type transporter involved in osmoprotection and ectoine catabolism
    Mohamed Jebbar
    Universite de Rennes I, UMR CNRS 6026, Departement Osmorégulation chez les Bactéries, Campus de Beaulieu, Av du Général Leclerc, 35042 Rennes, France
    J Bacteriol 187:1293-304. 2005
    To understand the mechanisms of ectoine-induced osmoprotection in Sinorhizobium meliloti, a proteomic examination of S. meliloti cells grown in minimal medium supplemented with ectoine was undertaken...
  76. pmc Functional analysis of Sinorhizobium meliloti genes involved in biotin synthesis and transport
    Plamena Entcheva
    Institut für Mikrobiologie und Genetik der Universität Göttingen, 37077 Gottingen, Germany
    Appl Environ Microbiol 68:2843-8. 2002
    External biotin greatly stimulates bacterial growth and alfalfa root colonization by Sinorhizobium meliloti strain 1021...
  77. pmc Identification of novel Sinorhizobium meliloti mutants compromised for oxidative stress protection and symbiosis
    Bryan W Davies
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    J Bacteriol 189:2110-3. 2007
    Employing a novel two-part screen, we identified Sinorhizobium meliloti mutants that were both sensitive to hydrogen peroxide and symbiotically defective on the host plant Medicago sativa...
  78. pmc alpha-Galactoside uptake in Rhizobium meliloti: isolation and characterization of agpA, a gene encoding a periplasmic binding protein required for melibiose and raffinose utilization
    D J Gage
    Department of Biological Sciences, Howard Hughes Medical Institute, Stanford University, Stanford, California 94305 5020, USA
    J Bacteriol 180:5739-48. 1998
    ..meliloti and at low levels in the free-living bacteria, we propose that AgpA may belong to the class of gene products whose expression decreases when R. meliloti becomes an intracellular symbiont...
  79. ncbi Expression of a class 1 hemoglobin gene and production of nitric oxide in response to symbiotic and pathogenic bacteria in Lotus japonicus
    Maki Nagata
    Graduate School of Science and Technology, Kagoshima University, Kagoshima, Japan
    Mol Plant Microbe Interact 21:1175-83. 2008
    ..In contrast, inoculation with the nonsymbiotic rhizobia Sinorhizobium meliloti and Bradyrhizobium japonicum induced neither expression of LjHb1 nor NO production. When L...
  80. pmc Sinorhizobium meliloti mutants lacking phosphotransferase system enzyme HPr or EIIA are altered in diverse processes, including carbon metabolism, cobalt requirements, and succinoglycan production
    Catalina Arango Pinedo
    Department of Molecular and Cell Biology, University of Connecticut, 91 N Eagleville Rd, U 3125, Storrs, CT 06269 3125, USA
    J Bacteriol 190:2947-56. 2008
    b>Sinorhizobium meliloti is a member of the Alphaproteobacteria that fixes nitrogen when it is in a symbiotic relationship. Genes for an incomplete phosphotransferase system (PTS) have been found in the genome of S. meliloti...
  81. pmc Differentiation of symbiotic cells and endosymbionts in Medicago truncatula nodulation are coupled to two transcriptome-switches
    Nicolas Maunoury
    Institut des Sciences du Vegetal, Centre National de la Recherche Scientifique, Unité Propre de Recherche 2355, Gif sur Yvette, France
    PLoS ONE 5:e9519. 2010
    The legume plant Medicago truncatula establishes a symbiosis with the nitrogen-fixing bacterium Sinorhizobium meliloti which takes place in root nodules...
  82. pmc A Sinorhizobium meliloti lipopolysaccharide mutant altered in cell surface sulfation
    David H Keating
    Howard Hughes Medical Institute Department of Biology, Stanford University, Stanford, California 94305, USA
    J Bacteriol 184:6681-9. 2002
    ..Nodule development requires a bacterial signal referred to as Nod factor, which in Sinorhizobium meliloti is a beta-(1,4)-linked tetramer of N-acetylglucosamine containing N-acyl and O-acetyl modifications at the ..
  83. ncbi The response to nitric oxide of the nitrogen-fixing symbiont Sinorhizobium meliloti
    Eliane Meilhoc
    Laboratoire des Interactions Plantes Microorganismes, UMR441 2594 INRA CNRS BP52627, R 31320 Castanet Tolosan, France
    Mol Plant Microbe Interact 23:748-59. 2010
    ..of NO during the symbiotic interaction between the model legume Medicago truncatula and its symbiont Sinorhizobium meliloti have been reported but the role of NO in symbiosis is far from being elucidated...
  84. ncbi Expression and regulation of phosphate stress inducible genes in Sinorhizobium meliloti
    M L Summers
    Department of Land Resources and Environmental Sciences, Montana State University, Bozeman 59717 3120, USA
    Mol Plant Microbe Interact 11:1094-101. 1998
    b>Sinorhizobium meliloti 104A14 was mutated with transposon Tn5B22, which creates lacZ transcriptional fusions when inserted in the correct orientation relative to the promoter...
  85. pmc Biosynthesis of UDP-xylose and UDP-arabinose in Sinorhizobium meliloti 1021: first characterization of a bacterial UDP-xylose synthase, and UDP-xylose 4-epimerase
    Xiaogang Gu
    Complex Carbohydrate Research Center CCRC, University of Georgia, Athens, GA 30602, USA
    Microbiology 157:260-9. 2011
    b>Sinorhizobium meliloti is a soil bacterium that fixes nitrogen after being established inside nodules that can form on the roots of several legumes, including Medicago truncatula. A mutation in an S...
  86. ncbi Structure and role in symbiosis of the exoB gene of Rhizobium leguminosarum bv trifolii
    B Sánchez-Andújar
    Departamento de Microbiologia, Facultad de Farmacia, Universidad de Sevilla, Spain
    Mol Gen Genet 255:131-40. 1997
    ..The exoB mutant induced the development of abnormal root nodules and was almost completely unable to invade plant cells. Our results stress the importance of exoB in the Rhizobium-plant interaction...
  87. ncbi Expression of Medicago truncatula genes responsive to nitric oxide in pathogenic and symbiotic conditions
    Alberto Ferrarini
    Dipartimento Scientifico e Tecnologico, Universita degli Studi di Verona, 37134 Verona, Italy
    Mol Plant Microbe Interact 21:781-90. 2008
    ..with the foliar pathogen Colletotrichum trifolii race 1 and during the symbiotic interaction with Sinorhizobium meliloti 1,021...
  88. pmc FixJ: a major regulator of the oxygen limitation response and late symbiotic functions of Sinorhizobium meliloti
    Christine Bobik
    Laboratoire des Interactions Plantes Microorganismes LIPM, UMR441 2594 CNRS INRA BP52627, Chemin de Borde Rouge, Auzeville, 31326 Castanet Tolosan Cedex, France
    J Bacteriol 188:4890-902. 2006
    b>Sinorhizobium meliloti exists either in a free-living state in the soil or in symbiosis within legume nodules, where the bacteria differentiate into nitrogen-fixing bacteroids...
  89. pmc Interrelations between glycine betaine catabolism and methionine biosynthesis in Sinorhizobium meliloti strain 102F34
    Lise Barra
    Osmorégulation chez les bactéries, UMR CNRS 6026, Universite de Rennes I, Campus de Beaulieu, Av du Général Leclerc, 35042 Rennes, France
    J Bacteriol 188:7195-204. 2006
    Methionine is produced by methylation of homocysteine. Sinorhizobium meliloti 102F34 possesses only one methionine synthase, which catalyzes the transfer of a methyl group from methyl tetrahydrofolate to homocysteine...
  90. pmc Biochemical characterization of Sinorhizobium meliloti mutants reveals gene products involved in the biosynthesis of the unusual lipid A very long-chain fatty acid
    Andreas F Haag
    School of Medicine and Dentistry, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom
    J Biol Chem 286:17455-66. 2011
    b>Sinorhizobium meliloti forms a symbiosis with the legume alfalfa, whereby it differentiates into a nitrogen-fixing bacteroid. The lipid A species of S...
  91. pmc Overlap of proteome changes in Medicago truncatula in response to auxin and Sinorhizobium meliloti
    Giel E van Noorden
    Australian Research Council Centre of Excellence for Integrative Legume Research, Australian National University, Canberra, Australian Capital Territory 0200, Australia
    Plant Physiol 144:1115-31. 2007
    ..mass spectrometry to compare proteomes of wild-type and sunn mutant roots after 24 h of treatment with Sinorhizobium meliloti, auxin, or a control. We identified 131 of 270 proteins responding to treatment with S...
  92. ncbi Medicago truncatula ENOD11: a novel RPRP-encoding early nodulin gene expressed during mycorrhization in arbuscule-containing cells
    E P Journet
    Laboratoire de Biologie Moleculaire des relations Plantes Microorganismes, CNRS INRA, Castanet Tolosan, France
    Mol Plant Microbe Interact 14:737-48. 2001
    ..The potential role of early nodulins with atypical RPRP structures such as ENOD11 and ENOD12 in symbiotic and nonsymbiotic cellular contexts is discussed...
  93. pmc The MtMMPL1 early nodulin is a novel member of the matrix metalloendoproteinase family with a role in Medicago truncatula infection by Sinorhizobium meliloti
    Jean Philippe Combier
    Laboratoire des Interactions Plantes Micro organismes, Centre National de la Recherche Scientifique Institut National de la Recherche Agronomique, 31326 Castanet Tolosan Cedex, France
    Plant Physiol 144:703-16. 2007
    ..identified by transcriptomics, represents a novel and specific marker for root and nodule infection by Sinorhizobium meliloti. This was established by determining the spatial pattern of MtMMPL1 expression and evaluating gene ..
  94. pmc Transcriptome analysis of Sinorhizobium meliloti during symbiosis
    Frederic Ampe
    Laboratoire de Biologie Moleculaire des relations Plantes Microorganismes, UMR 215 Centre National de la Recherche Scientifique Institut National de la Recherche Agronomique, BP27 31326 Castanet Tolosan Cedex, France
    Genome Biol 4:R15. 2003
    ..global view of the genetics underlying this plant-microbe symbiosis, we have mined the recently determined Sinorhizobium meliloti genome sequence for genes potentially relevant to symbiosis...
  95. ncbi A highly conserved Sinorhizobium meliloti operon is induced microaerobically via the FixLJ system and by nitric oxide (NO) via NnrR
    Frans J de Bruijn
    Laboratoire des Interactions Plantes Micro organismes LIPM, UMR CNRS 2594 INRA 441, BP 52627, 31326 Castanet Tolosan Cedex, France
    Environ Microbiol 8:1371-81. 2006
    A previously generated collection of 11 Tn5-luxAB insertion mutants of Sinorhizobium meliloti harbouring lux reporter gene fusions induced under microaerobic (1% O2) conditions was further characterized and mapped on the sequenced S...
  96. ncbi Sinorhizobium meliloti rpoE2 is necessary for H(2)O(2) stress resistance during the stationary growth phase
    Maud Flechard
    CNRS UMR6026 DUALS, Universite Rennes I, Rennes, France
    FEMS Microbiol Lett 290:25-31. 2009
    RpoE2 is an extracytoplasmic sigma factor produced by Sinorhizobium meliloti during stationary growth phase. Its inactivation affected the synthesis of the superoxide dismutase, SodC, and catalase, KatC...
  97. ncbi Effects of nutritional and environmental conditions on Sinorhizobium meliloti biofilm formation
    Luciana Rinaudi
    Departamento de Biologia Molecular, Universidad Nacional de Rio Cuarto, 5800 Rio Cuarto, Cordoba, Argentina
    Res Microbiol 157:867-75. 2006
    ..assays to study environmental parameters that might influence biofilm formation in the Medicago symbiont Sinorhizobium meliloti. These parameters include carbon source, amount of nitrate, phosphate, calcium and magnesium as well as ..
  98. pmc Identification and characterization of nodulation-signaling pathway 2, a gene of Medicago truncatula involved in Nod actor signaling
    Giles E D Oldroyd
    Department of Biological Sciences, Stanford University, Stanford, California 94305 5020, USA
    Plant Physiol 131:1027-32. 2003
    ..nsp2 plants also show a complete absence of infection and cortical cell division following Sinorhizobium meliloti inoculation...
  99. ncbi Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58
    B Goodner
    Department of Biology, Hiram College, Hiram, OH 44234, USA
    Science 294:2323-8. 2001
    ..We discuss genome architecture and evolution and additional genes potentially involved in virulence and metabolic parasitism of host plants...
  100. ncbi Stable low molecular weight RNA profiling showed variations within Sinorhizobium meliloti and Sinorhizobium medicae nodulating different legumes from the alfalfa cross-inoculation group
    María Del Villar
    Departamento de Microbiologia y Genetica, Universidad de Salamanca, Spain
    FEMS Microbiol Lett 282:273-81. 2008
    ..of each LMW RNA profile it was evident that isolates with LMW RNA profiles I and II belonged to Sinorhizobium meliloti and those displaying profiles III and IV to Sinorhizobium medicae...
  101. ncbi Mutational analysis of the Sinorhizobium meliloti short-chain dehydrogenase/reductase family reveals substantial contribution to symbiosis and catabolic diversity
    Asha I Jacob
    Department of Biology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada
    Mol Plant Microbe Interact 21:979-87. 2008
    ..study, we carried out a large-scale mutagenesis of the SDR gene family in the alfalfa root nodule symbiont Sinorhizobium meliloti. Subsequent phenotypic analysis revealed phenotypes for mutants of 21 of the SDR-encoding genes...

Research Grants22

  1. CYCLE REGULATION IN THE SYMBIONT SINORHIZOBIUM MELILOTI
    KATHERINE ELISABETH GIBSON; Fiscal Year: 2011
    ..cell cycle occurs during chronic host colonization in a variety of species, including our model organism Sinorhizobium meliloti. Insights gained from our analysis of cell cycle regulation in S...
  2. Regulatory Circuits Controlling Development of Dormant Microbial Cysts
    CARL EUGENE BAUER; Fiscal Year: 2013
    ..such as Azospirillum brasilense, Rhizobium leguminosarum, Mesorhizobium loti, Sinorhizobium medicae, Sinorhizobium meliloti, Sinorhizobium fredii, Delftia acidovorans (Comamonas acidovorans), Burkholderia mallei (Pseudomonas ..
  3. Structural and functional studies of autoinducer-2 processing proteins
    Stephen T Miller; Fiscal Year: 2012
    ..coli LsrF and LsrG and a putative functional homolog of LsrF from Sinorhizobium meliloti. Cell extracts will be analyzed by mass spectrometry and NMR to identify the products of these reactions...
  4. Control of Symbiotic Gene Expression in Sinorhizobium meliloti
    Sharon R Long; Fiscal Year: 2013
    ..These signal exchanges are critical to pathogenesis and to symbiosis. We study Sinorhizobium meliloti, an alpha- proteobacterium, which establishes a beneficial nitrogen fixing symbiosis with host plants ..
  5. Regulatory network of a conserved polar factor in Sinorhizobium meliloti
    JOSEPH CHIUNG CHU CHEN; Fiscal Year: 2013
    ..conserved polar factor controls multiple cell envelope-associated activities in the alpha- proteobacterium Sinorhizobium meliloti, which infects the roots of legume plants to form symbiosis...
  6. Regulated Assembly of Subcellular Structures in alpha-Proteobacteria
    JOSEPH CHIUNG CHU CHEN; Fiscal Year: 2010
    ..The regulatory components are conserved in Sinorhizobium meliloti, a related bacterium that induces nodule formation in plant roots during symbiosis. However, S...
  7. A periplasmic global regulator, ExoR, for Bacterial invasion of host cells
    Hai Ping Cheng; Fiscal Year: 2012
    ..bacterial sensing and signaling during host cell invasion, we are studying the molecular mechanism of Sinorhizobium meliloti ExoR protein in controlling the switch from free living cells to invasion ready cells...
  8. Quorum Sensing in Sinorhizobium meliloti
    Juan Gonzalez; Fiscal Year: 2009
    The symbiotic relationship between the nitrogen-fixing Sinorhizobium meliloti and its legume host (Medicago sativa) is the result of an intricate signaling network between the host and the symbiont...
  9. Biosynthesis and Physiology of Vitamin B12 in Prokaryotes
    MICHIKO TAGA; Fiscal Year: 2009
    ..identified BluB, an enzyme that catalyzes the production of DMB in the symbiotic nitrogen fixing bacterium Sinorhizobium meliloti. The bluB mutant of S...
  10. STRUCTURE AND DYNAMICS OF HEME PROTEIN ACTIVE SITES
    JAMES SATTERLEE; Fiscal Year: 2005
    ..These include the FixLs from Bradyrhizobium japonicum (BjFixL) and Sinorhizobium meliloti (SmFixL) and the Direct Oxygen Sensor protein from E. coli (EcDos)...
  11. Modulation of two-component signaling in alphaproteobacteria
    Joel Griffitts; Fiscal Year: 2009
    ..Using the plant symbiont Sinorhizobium meliloti as a model for chronic infection, a novel `two-component'phosphotransfer system required for cyclic ..
  12. Heme as an iron source in Sinorhizobium meliloti
    MARK O BRIAN; Fiscal Year: 2008
    ..It was shown recently that S. meliloti uses heme as a nutritional iron source in Sinorhizobium meliloti and related species. The ?-proteobacterial group to which S...
  13. Evolution of Estrogen Receptor-Ligand Interactions
    Jennifer Fox; Fiscal Year: 2006
    ..Such an experimental system will allow the rigorous testing of hypotheses about ER-ligand structure function relationships and the dynamics of receptor-ligand coevolution. ..
  14. Siderophore transport mechanism via membrane receptors
    Ranjan Chakraborty; Fiscal Year: 2004
    ..For the mutant proteins showing normal binding and defective transport, methods of purification and crystallization will be standardized. ..
  15. Genetic Systems Bioengineering for Escherichia coli
    Alexander Ninfa; Fiscal Year: 2009
    ..In addition we propose designs for novel genetic clocks that test the role of various system design principles in the production of biological oscillations. ..
  16. Elucidating the Conformational Dynamics of the AAA+ ATPases NtrC1 and NtrC
    B Nixon; Fiscal Year: 2009
    ..In the course of performing this research, new tools will be developed that are expected to be broadly applicable to similar studies of other proteins that are vital for human health. ..
  17. Structure/function analysis of the E. coli NIR/NRII signal transduction system
    Alexander Ninfa; Fiscal Year: 2009
    ..Our studies with a model system should allow rapid progress. ..
  18. Phenanthroline Derivatives in Asymmetric Catalysis
    Elke Schoffers; Fiscal Year: 2003
    ..These experimental approaches will be complemented with computational ligand design based on molecular mechanics tools. ..
  19. INTERACTIONS OF THE SIGNAL TRANSDUCTION PROTEIN GLNK
    Alexander Ninfa; Fiscal Year: 2002
    ..These experiments should elucidate the design of the signal transduction system controlling nitrogen assimilation, and the mechanisms of interaction of PII and GlnK with their receptors and small molecule effectors. ..
  20. MOLECULAR SEQUENCE DATA
    Samuel Karlin; Fiscal Year: 2001
    ..by spacings between repeats, and by properties of repeat families (intergenic, coding, direct, inverted, mixed). ..
  21. Gene Expression Levels Across Diverse Genomes
    Samuel Karlin; Fiscal Year: 2006
    ..A third major objective of our research will be to extend our codon usage methods for predicting gene expression levels to eukaryotic genomes, including yeast, D. melanogaster, C. elegans, and human. [unreadable] [unreadable]..