Genomes and Genes
Summary: A phylum of bacteria consisting of the purple bacteria and their relatives which form a branch of the eubacterial tree. This group of predominantly gram-negative bacteria is classified based on homology of equivalent nucleotide sequences of 16S ribosomal RNA or by hybridization of ribosomal RNA or DNA with 16S and 23S ribosomal RNA.
Publications286 found, 100 shown here
- Deciphering the rhizosphere microbiome for disease-suppressive bacteriaRodrigo Mendes
Laboratory of Phytopathology, Wageningen University, Droevendaalsesteeg 1, Wageningen 6700 EE, Netherlands
Science 332:1097-100. 2011..More than 33,000 bacterial and archaeal species were detected, with Proteobacteria, Firmicutes, and Actinobacteria consistently associated with disease suppression...
- A novel lineage of proteobacteria involved in formation of marine Fe-oxidizing microbial mat communitiesDavid Emerson
American Type Culture Collection, Manassas, Virginia, United States of America
PLoS ONE 2:e667. 2007..We have used both cultivation and cultivation-independent techniques to study Fe-rich microbial mats associated with hydrothermal venting at Loihi Seamount, a submarine volcano...
- Deep-sea vent chemoautotrophs: diversity, biochemistry and ecological significanceSatoshi Nakagawa
Subground Animalcule Retrieval Program, Extremobiosphere Research Center, Japan Agency for Marine Earth Science and Technology, Yokosuka, Japan
FEMS Microbiol Ecol 65:1-14. 2008..This review summarizes chemoautotrophy in deep-sea vents, highlighting recent biochemical and genomic discoveries...
- Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soilsNaomi L Ward
The Institute for Genomic Research, Rockville, Maryland 20850, USA
Appl Environ Microbiol 75:2046-56. 2009..Phylogenetic analysis placed them as a unique phylum. They share genomic traits with members of the Proteobacteria, the Cyanobacteria, and the Fungi. The three strains appear to be versatile heterotrophs...
- Host remodeling of the gut microbiome and metabolic changes during pregnancyOmry Koren
Department of Microbiology, Cornell University, Ithaca, NY 14853, USA
Cell 150:470-80. 2012..first (T1) to third (T3) trimesters, with vast expansion of diversity between mothers, an overall increase in Proteobacteria and Actinobacteria, and reduced richness...
- Lithotrophic iron-oxidizing bacteria produce organic stalks to control mineral growth: implications for biosignature formationClara S Chan
Department of Marine Chemistry and Geochemistry, Woods Hole Oceanographic Institution, Woods Hole, MA, USA
ISME J 5:717-27. 2011..We suggest that stalk-like morphologies observed in modern and ancient samples may be correlated confidently with the Fe-oxidizing metabolism as a robust biosignature...
- AHL-driven quorum-sensing circuits: their frequency and function among the ProteobacteriaRebecca J Case
The Centre of Marine Bio Innovation, University of New South Wales, Sydney, New South Wales, Australia
ISME J 2:345-9. 2008
- Quantitative detection of the nosZ gene, encoding nitrous oxide reductase, and comparison of the abundances of 16S rRNA, narG, nirK, and nosZ genes in soilsS Henry
INRA University of Burgundy, Microbiology and Soil Geochemistry, CMSE, 17 rue Sully, B P 86510, 21065 Dijon Cedex, France
Appl Environ Microbiol 72:5181-9. 2006..The two sets of nosZ primers gave similar gene copy numbers for all tested soils. The maximum abundance of nosZ and nirK relative to 16S rRNA was 5 to 6%, confirming the low proportion of denitrifiers to total bacteria in soils...
- Abundance of Zetaproteobacteria within crustal fluids in back-arc hydrothermal fields of the Southern Mariana TroughShingo Kato
Department of Molecular Biology, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
Environ Microbiol 11:3210-22. 2009..Our results lead to the hypothesis that the Zetaproteobacteria play a role in iron oxidation within the oceanic crust...
- Mariprofundus ferrooxydans PV-1 the first genome of a marine Fe(II) oxidizing ZetaproteobacteriumEsther Singer
Geomicrobiology Group, Department of Earth Sciences, University of Southern California, Los Angeles, California, United States of America
PLoS ONE 6:e25386. 2011..This study has provided novel insights into the molecular nature of Zetaproteobacteria...
- Living without Fur: the subtlety and complexity of iron-responsive gene regulation in the symbiotic bacterium Rhizobium and other alpha-proteobacteriaAndrew W B Johnston
School of Biological Sciences, University of East Anglia, Norwich, NR4 7TJ, UK
Biometals 20:501-11. 2007The alpha-proteobacteria include several important genera, including the symbiotic N(2)-fixing "rhizobia", the plant pathogen Agrobacterium, the mammalian pathogens Brucella, Bartonella as well as many others that are of environmental or ..
- Bacterial diversity and activity along a salinity gradient in soda lakes of the Kulunda Steppe (Altai, Russia)Mirjam J Foti
Department of Biotechnology, Delft University of Technology, Julianalaan 67, 2628 BC Delft, The Netherlands
Extremophiles 12:133-45. 2008..showed the presence of minor, but highly active microbial populations, mostly represented by members of the Proteobacteria. Remarkably high SRR were measured at hypersaline conditions (200 g L(-1))...
- Horizontal transfer of the photosynthesis gene cluster and operon rearrangement in purple bacteriaN Igarashi
Department of Biology, Tokyo Metropolitan University, Minamiohsawa 1-1, Hachioji, Tokyo 192-0397, Japan
J Mol Evol 52:333-41. 2001..gene cluster was sequenced in a photosynthetic bacterium belonging to the beta subclass of purple bacteria (Proteobacteria), Rubrivivax gelatinosus...
- Amyloid adhesins are abundant in natural biofilmsPoul Larsen
Department of Biotechnology, Aalborg University, Sohngaardsholmvej 57, DK 9000, Aalborg, Denmark
Environ Microbiol 9:3077-90. 2007..natural habitats, bacteria producing extracellular amyloid adhesins were identified within several phyla: Proteobacteria (Alpha-, Beta-, Gamma- and Deltaproteobacteria), Bacteriodetes, Chloroflexi and Actinobacteria, and most ..
- Diversity and function of epibiotic microbial communities on the galatheid crab, Shinkaia crosnieriTomo o Watsuji
Subsurface Geobiology Advanced Research Team SUGAR, Extremobiosphere Research Program XBR, Japan Agency for Marine Earth Science and Technology JAMSTEC, 2 15 Natsushima cho, Yokosuka 237 0061
Microbes Environ 25:288-94. 2010..In conclusion, the uptake experiments suggested that sulfur-oxidizing chemolithoautotrophic and methanotrophic production by the epibionts provides the nutrition for S. crosnieri...
- Molecular characterization of putative biocorroding microbiota with a novel niche detection of Epsilon- and Zetaproteobacteria in Pacific Ocean coastal seawatersHongyue Dang
State Key Laboratory of Heavy Oil Processing and Centre for Bioengineering and Biotechnology, China University of Petroleum East China, Qingdao 266555, China
Environ Microbiol 13:3059-74. 2011..Further studies of Epsilon- and Zetaproteobacteria in particular may thus help with the design of effective corrosion prevention and control strategies...
- Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient miceFrederic A Carvalho
Center for Inflammation, Immunity, and Infection, Georgia State University, Atlanta, 30303, USA
Cell Host Microbe 12:139-52. 2012..Transient high levels of proteobacteria, especially enterobacteria species including E...
- New evidence for bacterial diversity in the ascoma of the ectomycorrhizal fungus Tuber borchii VittadElena Barbieri
Istituto di Chimica Biologica Giorgio Fornaini, University of Urbino Carlo Bo, Urbino PU, Italy
FEMS Microbiol Lett 247:23-35. 2005..Most of the isolates were affiliated to the gamma-Proteobacteria, mainly Fluorescent pseudomonads; some isolates were members of the Bacteroidetes group and Gram-positive ..
- Biochemical evidence for formate transfer in syntrophic propionate-oxidizing cocultures of Syntrophobacter fumaroxidans and Methanospirillum hungateiFrank A M de Bok
Laboratory of Microbiology, Wageningen University, The Netherlands
Appl Environ Microbiol 68:4247-52. 2002..fumaroxidans cultures that exhibited the highest formate dehydrogenase activities. The results suggest that formate is the preferred electron carrier in syntrophic propionate-oxidizing cocultures of S. fumaroxidans and M. hungatei...
- Occurrence and diversity of bacterial communities in Tuber magnatum during truffle maturationElena Barbieri
Istituto di Chimica Biologica Giorgio Fornaini, Via Saffi, 2, University of Urbino Carlo Bo, 61029 Urbino, Italy
Environ Microbiol 9:2234-46. 2007..Sequencing results from the clone library showed a significant presence of alpha-Proteobacteria (634 of the 771 total clones screened, c. 82%) affiliated with Sinorhizobium, Rhizobium and Bradyrhizobium spp...
- Bacterial diversity in Fe-rich hydrothermal sediments at two South Tonga Arc submarine volcanoesN L Forget
Department of Biology, University of Victoria, Petch Building 116, 3800 Finnerty Rd, Victoria, BC, Canada
Geobiology 8:417-32. 2010..The results of this study suggest that Fe-rich hydrothermal sediments, while dominated by Fe oxidizers, can be exploited by a variety of autotrophic and heterotrophic micro-organisms...
- Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110Takakazu Kaneko
Kazusa DNA Research Institute, 2 6 7 Kazusa Kamatari, Kisarazu, Chiba 292 0812, Japan
DNA Res 9:189-97. 2002..These observations suggest plasticity of the B. japonicum genome, which is probably due to complex genome rearrangements such as horizontal transfer and insertion of various DNA elements, and to homologous recombination...
- Phylogeny of Proteobacteria and Bacteroidetes from oxic habitats of a tidal flat ecosystemHeike Stevens
Institute for Chemistry and Biology of the Marine Environment ICBM, University of Oldenburg, P O Box 2503, D 26111 Oldenburg, Germany
FEMS Microbiol Ecol 54:351-65. 2005Bacteria of the phyla Proteobacteria and Bacteroidetes are known to be the most prominent heterotrophic organisms in marine surface waters...
- Distribution and selection of poly-3-hydroxybutyrate production capacity in methanotrophic proteobacteriaAllison J Pieja
Environmental Engineering and Science, Department of Civil and Environmental Engineering, Stanford University, Stanford, CA 94305, USA
Microb Ecol 62:564-73. 2011....
- Characterization of the first alginolytic operons in a marine bacterium: from their emergence in marine Flavobacteriia to their independent transfers to marine Proteobacteria and human gut BacteroidesFrançois Thomas
UPMC University Paris 6, UMR 7139 Marine Plants and Biomolecules, Station Biologique de Roscoff, F 29682 Roscoff, Brittany, France
Environ Microbiol 14:2379-94. 2012..operons originated from an ancestral marine flavobacterium and were independently transferred to marine proteobacteria and Japanese gut Bacteroides...
- The photosynthetic apparatus and its regulation in the aerobic gammaproteobacterium Congregibacter litoralis gen. nov., sp. novStefan Spring
Deutsche Sammlung von Mikroorganismen und Zellkulturen, Braunschweig, Germany
PLoS ONE 4:e4866. 2009..The interaction of photosynthesis and carbon metabolism in these interesting bacteria is still largely unknown and requires further investigation in order to estimate their contribution to the marine carbon cycle...
- Abundance, composition, diversity and novelty of soil ProteobacteriaAnne M Spain
Department of Botany and Microbiology and Institute for Energy and the Environment, University of Oklahoma, Norman, OK, USA
ISME J 3:992-1000. 2009..This study offers a detailed phylogenetic analysis of the Proteobacteria-affiliated clones identified from 13,001 nearly full-length 16S rRNA gene clones derived from Oklahoma tall-..
- Expanding small-molecule functional metagenomics through parallel screening of broad-host-range cosmid environmental DNA libraries in diverse proteobacteriaJeffrey W Craig
Howard Hughes Medical Institute, Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, 1230 York Avenue, New York, New York 10065, USA
Appl Environ Microbiol 76:1633-41. 2010..studies, we report the phenotypic screening of broad-host-range environmental DNA libraries in six different proteobacteria: Agrobacterium tumefaciens, Burkholderia graminis, Caulobacter vibrioides, Escherichia coli, Pseudomonas ..
- Transposon mutagenesis in purple sulfur photosynthetic bacteria: identification of hypF, encoding a protein capable of processing [NiFe] hydrogenases in alpha, beta, and gamma subdivisions of the proteobacteriaB Fodor
Institute of Biophysics, Biological Research Center, Hungarian Academy of Sciences, and Department of Biotechnology, University of Szeged, H 6726 Szeged, Hungary
Appl Environ Microbiol 67:2476-83. 2001..RT-PCR data suggested that HypF has no effect on the transcriptional regulation of the structural genes of hydrogenases in this organism...
- Cultivation of denitrifying bacteria: optimization of isolation conditions and diversity studyKim Heylen
Laboratory of Microbiology, Department of Biochemistry, Physiology and Microbiology, Ghent University, K L Ledeganckstraat 35, B 9000 Ghent, Belgium
Appl Environ Microbiol 72:2637-43. 2006..This study revealed a much more diverse denitrifying community than that previously described in cultivation-dependent research on activated sludge...
- Molecular characterization of methanotrophic isolates from freshwater lake sedimentA J Auman
Departments of Microbiology, University of Washington, Seattle, Washington 98195, USA
Appl Environ Microbiol 66:5259-66. 2000..The presence of sMMO-containing Methylomonas strains in a pristine freshwater lake environment suggests that these methanotrophs are more widespread than has been previously thought...
- Diversity and quorum-sensing signal production of Proteobacteria associated with marine spongesNaglaa M Mohamed
Center of Marine Biotechnology, University of Maryland Biotechnology Institute, Baltimore, MD 21202, USA
Environ Microbiol 10:75-86. 2008..Given that marine Proteobacteria are known to produce N-acyl homoserine lactone (AHL) signal molecules, we tested the production of AHLs by ..
- Improved culturability of soil bacteria and isolation in pure culture of novel members of the divisions Acidobacteria, Actinobacteria, Proteobacteria, and VerrucomicrobiaPeter H Janssen
Department of Microbiology and Immunology, University of Melbourne, Victoria 3010, Australia
Appl Environ Microbiol 68:2391-6. 2002..A large proportion of these isolates represent the first known isolates of globally distributed groups of soil bacteria belonging to novel lineages within the divisions Actinobacteria, Acidobacteria, Proteobacteria, and Verrucomicrobia.
- Unexpected diversity and complexity of the Guerrero Negro hypersaline microbial matRuth E Ley
Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309 0347, USA
Appl Environ Microbiol 72:3685-95. 2006..The sequences determined in this study have been submitted to the GenBank database and assigned accession numbers DQ 329539 to DQ 331020, and DQ 397339 to DQ 397511...
- Molecular analyses of the microbial community composition of an anoxic basin of a municipal wastewater treatment plant reveal a novel lineage of proteobacteriaRakia Chouari
Faculte des Sciences de Bizerte, Université 7 Novembre à Carthage, Bizerte, Tunisia
Microb Ecol 60:272-81. 2010..The Proteobacteria phylum is the most abundant and diversified phylogenetic group representing 60...
- Multiple Rubisco forms in proteobacteria: their functional significance in relation to CO2 acquisition by the CBB cycleMurray Ronald Badger
Molecular Plant Physiology Group, Research School of Biological Sciences, The Australian National University, Canberra, ACT, Australia
J Exp Bot 59:1525-41. 2008..The most dramatic evidence of this is the occurrence of multiple forms of Rubisco within autotrophic proteobacteria, where Forms II, IC, IBc, IAc, and IAq can be found either singly or in multiple combinations within a ..
- Genomes on the shrinkHoward Ochman
Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, AZ 85721, USA
Proc Natl Acad Sci U S A 102:11959-60. 2005
- Responses of benthic bacteria to experimental drying in sediments from Mediterranean temporary riversStefano Amalfitano
Water Research Institute IRSA CNR, Via Reno 1, 00198 Rome, Italy
Microb Ecol 55:270-9. 2008..Community composition analysis showed a relative increase in alpha- and beta-Proteobacteria, when passing from wet to dry conditions...
- High-diversity biofilm for the oxidation of sulfide-containing effluentsI Ferrera
Departament de Genetica i de Microbiologia, Universitat Autonoma de Barcelona, 08193, Bellaterra, Spain
Appl Microbiol Biotechnol 64:726-34. 2004..The clone library was dominated by alpha-Proteobacteria (mostly Rhodobacter group), followed by gamma-Proteobacteria (Chromatiaceae-like and Thiothrix-like aerobic ..
- Remarkable diversity of phototrophic purple bacteria in a permanently frozen Antarctic lakeElizabeth A Karr
Department of Microbiology, Southern Illinois University, Carbondale, Illinois 62901 6508, USA
Appl Environ Microbiol 69:4910-4. 2003..The isolates also contained gas vesicles, buoyancy structures previously unknown in purple nonsulfur bacteria, that may be necessary for these organisms to position themselves at specific depths within the nearly freezing water column...
- Comparison of cultivation-dependent and molecular methods for studying the diversity of anoxygenic purple phototrophs in sediments of an eutrophic brackish lagoonAnthony Ranchou-Peyruse
Laboratoire d Ecologie Moléculaire Microbiologie, EA3525, Universite de Pau et des Pays de l Adour, 64013 Pau Cedex, France
Environ Microbiol 8:1590-9. 2006....
- Vertical distribution of bacteria in a lake sediment from Antarctica by culture-independent and culture-dependent approachesSisinthy Shivaji
Center for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India
Res Microbiol 162:191-203. 2011..at the phyla level using T-RFLP and 16S rRNA clone libraries was similar and clones were affiliated with Proteobacteria, Bacteroidetes, Actinobacteria and Firmicutes...
- Proteobacteria-like ferrochelatase in the malaria parasiteShigeharu Sato
Division of Parasitology, National Institute for Medical Research, The Ridgeway, Mill Hill, NW7 1AA, London, UK
Curr Genet 42:292-300. 2003..This suggests an unusual intracellular distribution of heme biosynthetic enzymes, involving multiple subcellular compartments...
- In silico prediction of human pathogenicity in the γ-proteobacteriaMassimo Andreatta
Center for Biological Sequence Analysis, Technical University of Denmark, Kongens Lyngby, Denmark
PLoS ONE 5:e13680. 2010..Bioinformatics-based methods are therefore strongly needed to mine the fast growing number of genome sequences and assess in a rapid and reliable way the pathogenicity of novel bacteria...
- Biochemical Society Special Lecture. Nitrate- and nitrite-responsive sensors NarX and NarQ of proteobacteriaV Stewart
Section of Microbiology, University of California, 1 Shields Avenue, Davis, CA 95616 8665, USA
Biochem Soc Trans 31:1-10. 2003..Several other species classified in the gamma and beta subdivisions of the proteobacteria contain only a single Nar two-component regulatory pair...
- IBD-what role do Proteobacteria play?Indrani Mukhopadhya
Gastrointestinal Research Group, Division of Applied Medicine, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK
Nat Rev Gastroenterol Hepatol 9:219-30. 2012..Microbial diversity studies have continually demonstrated an expansion of the Proteobacteria phylum in patients with IBD...
- Bacterial diversity based on 16S rRNA and gyrB genes at Yinshan mine, ChinaHuaqun Yin
School of Minerals Processing and Bioengineering, Central South University, Changsha, Hunan, China
Syst Appl Microbiol 31:302-11. 2008..Moreover, the Mantel test showed that the geochemical characteristics, especially the pH value and the concentration of iron, strongly influenced the composition of the microbial communities...
- Sulfur-oxidizing chemolithotrophic proteobacteria dominate the microbiota in high arctic thermal springs on SvalbardLaila Johanne Reigstad
Center for Geobiology, Department of Biology, University of Bergen, Bergen, Norway
Astrobiology 11:665-78. 2011....
- Chemical characterization of lipid A from some marine proteobacteriaI N Krasikova
Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, pr 100 letiya Vladivostoka 159, Vladivostok, 690022 Russia
Biochemistry (Mosc) 66:1047-54. 2001Lipids A from type and wild strains of marine Proteobacteria belonging to Alteromonadaceae (Alteromonas (1 species), Idiomarina (1 species), and Pseudoalteromonas (8 species) genera) and Vibrionaceae (Shewanella (1 species) and Vibrio (1 ..
- Phylogeny of the 1-aminocyclopropane-1-carboxylic acid deaminase-encoding gene acdS in phytobeneficial and pathogenic Proteobacteria and relation with strain biogeographyDidier Blaha
UMR CNRS 5557 Ecologie Microbienne, Universite Claude Bernard, Villeurbanne, France
FEMS Microbiol Ecol 56:455-70. 2006..Two clusters gathered both Betaprotobacteria and Gammaproteobacteria, suggesting extensive horizontal transfers of acdS, noticeably between plant-associated Proteobacteria.
- Periplasmic glucans isolated from ProteobacteriaSanghoo Lee
Department of Bioscience and Biotechnology, Bio Molecular Informatics Center, Konkuk University, Seoul 143 701, Korea
BMB Rep 42:769-75. 2009Periplasmic glucans (PGs) are general constituents in the periplasmic space of Proteobacteria. PGs from bacterial strains are found in larger amounts during growth on medium with low osmolarity and thus are often been specified as ..
- Diversity of microorganisms in Fe-As-rich acid mine drainage waters of Carnoulès, FranceO Bruneel
Laboratoire Hydrosciences Montpellier, UMR5569, Universite Montpellier 2, Place E Bataillon, Case MSE, 34095 Montpellier Cedex 05, France
Appl Environ Microbiol 72:551-6. 2006..The description of the bacterial community structure and its dynamics lead to a better understanding of the natural remediation processes occurring at this site...
- Rapid and simultaneous detection of linear chromosome and large plasmids in ProteobacteriaMartha Helena Ramírez-Bahena
Université de Lyon Université Lyon, Lyon, France
J Basic Microbiol 52:736-9. 2012....
- The iron-oxidizing proteobacteriaSabrina Hedrich
School of Biological Sciences, College of Natural Sciences, Bangor University, Deiniol Road, Bangor LL57 2UW, UK
Microbiology 157:1551-64. 2011..While species of iron-oxidizing bacteria can be found in many different phyla, most are affiliated with the Proteobacteria. The latter can be subdivided into four main physiological groups: (i) acidophilic, aerobic iron oxidizers; (..
- New computational methods reveal tRNA identity element divergence between Proteobacteria and CyanobacteriaEva Freyhult
The Linnaeus Centre for Bioinformatics, Uppsala University, Box 598, 751 24 Uppsala, Sweden
Biochimie 89:1276-88. 2007..Here we show evidence that determinants for lysylated isoleucine tRNAs are not the same in Proteobacteria as in other bacterial groups including the Cyanobacteria...
- Relative abundances of proteobacterial membrane-bound and periplasmic nitrate reductases in selected environmentsD Bru
INRA, University of Burgundy, Soil and Environmental Microbiology, CMSE, 17 rue Sully, BP 86510, 21065 Dijon Cedex, France
Appl Environ Microbiol 73:5971-4. 2007..8 x 10(4) copies per ng of DNA. This study provides evidence that, in soil samples, the number of proteobacteria carrying the napA gene is often as high as that of proteobacteria carrying the narG gene...
- Osmoregulated periplasmic glucans in ProteobacteriaJ P Bohin
Laboratoire de Chimie Biologique, CNRS UMR 8576, Universite des Sciences et Technologies de Lille, 59655, Villeneuve d Ascq, France
FEMS Microbiol Lett 186:11-9. 2000Large amounts of osmoregulated periplasmic glucans (OPGs) are found in the periplasmic space of Proteobacteria. Four families of OPGs are described on the basis of structural features of the polyglucose backbone...
- The phylogeny of proteobacteria: relationships to other eubacterial phyla and eukaryotesR S Gupta
Department of Biochemistry, McMaster University, L8N 3Z5, Hamilton, Ont, Canada
FEMS Microbiol Rev 24:367-402. 2000The evolutionary relationships of proteobacteria, which comprise the largest and phenotypically most diverse division among prokaryotes, are examined based on the analyses of available molecular sequence data...
- PyCogent: a toolkit for making sense from sequenceRob Knight
Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado, USA
Genome Biol 8:R171. 2007..The toolkit takes advantage of parallel architectures and runs on a range of hardware and operating systems, and is available under the general public license from http://sourceforge.net/projects/pycogent...
- Cultivation of globally distributed soil bacteria from phylogenetic lineages previously only detected in cultivation-independent surveysMichelle Sait
Department of Microbiology and Immunology, The University of Melbourne, Victoria 3010, Australia
Environ Microbiol 4:654-66. 2002....
- DddY, a periplasmic dimethylsulfoniopropionate lyase found in taxonomically diverse species of ProteobacteriaAndrew R J Curson
School of Biological Sciences, University of East Anglia, Norwich, UK
ISME J 5:1191-200. 2011..There are dddY-like genes in strains of Alcaligenes, Arcobacter and Shewanella, in the β-, ɛ- and γ-proteobacteria, respectively...
- The genus Caedibacter comprises endosymbionts of Paramecium spp. related to the Rickettsiales (Alphaproteobacteria) and to Francisella tularensis (Gammaproteobacteria)Cora L Beier
Lehrstuhl fur Mikrobiologie, Technische Universitat Munchen, D 85350 Freising, Germany
Appl Environ Microbiol 68:6043-50. 2002..comprises at least two phylogenetically different bacterial species belonging to two different classes of the PROTEOBACTERIA: Comparative phylogenetic analysis of C...
- Detection of methanogens and proteobacteria from a single cell of rumen ciliate protozoaChagan Irbis
Laboratory of Animal Science, Kyoto Prefectural University, Kyoto 606 8522, Japan
J Gen Appl Microbiol 50:203-12. 2004..A range of proteobacteria was retrieved from cells of P. multivesiculatum...
- Fingerprinting diazotroph communities in the Chesapeake Bay by using a DNA macroarrayBethany D Jenkins
University of California, Santa Cruz, Santa Cruz, California 95064, USA
Appl Environ Microbiol 70:1767-76. 2004..M. Short, B. D. Jenkins, and J. P. Zehr, Appl. Environ. Microbiol., in press). The results show that DNA macroarrays have great potential for mapping the spatial and temporal variability of functional gene diversity in the environment...
- Widespread distribution of a lexA-regulated DNA damage-inducible multiple gene cassette in the Proteobacteria phylumMarc Abella
Departament de Genetica i Microbiologia, Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain
Mol Microbiol 54:212-22. 2004..In addition, in silico analyses reveal that this multiple gene cassette is also present in many Proteobacteria families, and that both its gene content and LexA-binding sequence have evolved over time, ultimately giving ..
- Neutrophilic iron-oxidizing "zetaproteobacteria" and mild steel corrosion in nearshore marine environmentsJoyce M McBeth
Bigelow Laboratory for Ocean Sciences, Box 475, 180 McKown Point Road, West Boothbay Harbor, ME 04575, USA
Appl Environ Microbiol 77:1405-12. 2011..In addition, this work shows that the global distribution of Zetaproteobacteria is far greater than previously thought...
- Distinguishable codon usage and amino acid composition patterns among substrates of leaderless secretory pathways from proteobacteriaInāra Kampenusa
Institute of Microbiology and Biotechnology, University of Latvia, Riga, Latvia, Kronvalda boulevard 4, LV 1010 Riga, Latvia
Appl Microbiol Biotechnol 86:285-93. 2010..from the 111 annotated sequences of leaderless secreted type I, type III, type IV, and type VI proteins from proteobacteria were subjected to the forward and backward selection to obtain a combination of most effective predictor ..
- The dif/Xer recombination systems in proteobacteriaChristophe Carnoy
Inserm U801, Lille, France
PLoS ONE 4:e6531. 2009..The aim of the present study was to extensively characterize the dif/Xer system in the proteobacteria, since this taxon accounts for the majority of genomes sequenced to date...
- Chemical communication in proteobacteria: biochemical and structural studies of signal synthases and receptors required for intercellular signallingKatherine M Pappas
Department of Genetics and Biotechnology, Faculty of Biology, University of Athens, Athens, Greece
Mol Microbiol 53:755-69. 2004..One class of chemical signals widely used by proteobacteria consists of N-acyl-homoserine lactones, which are synthesized by proteins related to LuxI of Vibrio fischeri ..
- Comparison of ATPase-encoding type III secretion system hrcN genes in biocontrol fluorescent Pseudomonads and in phytopathogenic proteobacteriaFabio Rezzonico
Phytopathology Group, Institute of Plant Sciences, Swiss Federal Institute of Technology, Zurich, Switzerland
Appl Environ Microbiol 70:5119-31. 2004Type III protein secretion systems play a key role in the virulence of many pathogenic proteobacteria, but they also occur in nonpathogenic, plant-associated bacteria. Certain type III protein secretion genes (e.g...
- Highly divergent RfaH orthologs from pathogenic proteobacteria can substitute for Escherichia coli RfaH both in vivo and in vitroHeather D Carter
Department of Microbiology, The Ohio State University, 376 BioSciences Building, 484 West 12th Avenue, Columbus, OH 43210, USA
J Bacteriol 186:2829-40. 2004..coli gene. Thus, despite the apparently accelerated divergent evolution of the RfaH proteins, the mechanism of their action is conserved well enough to make them transcriptionally active in the E. coli system...
- Endophytic bacterial diversity in poplar trees growing on a BTEX-contaminated site: the characterisation of isolates with potential to enhance phytoremediationFiona Porteous Moore
Macaulay Institute, Craigiebuckler, Aberdeen, Scotland, AB15 8QH, UK
Syst Appl Microbiol 29:539-56. 2006..This study demonstrates that within the diverse bacterial communities found in poplar several endophytic strains are present that have the potential to enhance phytoremediation strategies...
- Stepwise evolution of the Sec machinery in ProteobacteriaEli O van der Sluis
Department of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9751 NN Haren, The Netherlands
Trends Microbiol 14:105-8. 2006..In several of the Proteobacteria, this machinery contains accessory features that are not present in any other bacterial division...
- PpsR: a multifaceted regulator of photosynthesis gene expression in purple bacteriaSylvie Elsen
Laboratoire de Biochimie et Biophysique des Systèmes Intégrés UMR 5092 CNRS CEA UJF, CEA Grenoble, 38054 Grenoble Cedex 9, France
Mol Microbiol 57:17-26. 2005....
- CHDL: a cadherin-like domain in Proteobacteria and CyanobacteriaLihuan Cao
State Key Laboratory of Genetic Engineering, Institute of Genetics, Fudan University, Shanghai 200433, PR China
FEMS Microbiol Lett 251:203-9. 2005..The CHDL domain is mostly distributed in Proteobacteria and Cyanobacteria, although it is also found in some eukaryotic proteins...
- Identification of disulfide reductases in Campylobacterales: a bioinformatics investigationNadeem O Kaakoush
School of Medical Sciences, The University of New South Wales, Sydney, NSW 2052, Australia
Antonie Van Leeuwenhoek 92:429-41. 2007..TrxB(1) proteins were more closely related to those of Firmicutes than to the corresponding proteins of other Proteobacteria. The Campylobacterales TrxB(2) proteins were closer to glutathione reductases of other organisms than to their ..
- ClpV, a unique Hsp100/Clp member of pathogenic proteobacteriaChristian Schlieker
Zentrum fur Molekulare Biologie, Universitat Heidelberg, Im Neuenheimer Feld 282, D 69120 Heidelberg, Germany
Biol Chem 386:1115-27. 2005..typhimurium or Yersinia pseudotuberculosis ClpV strongly reduce the ability of these pathogenic bacteria to invade epithelial cells. We propose a role of this novel and unique class of AAA+ proteins in bacteria-host cell interactions...
- The origin and evolution of operons: the piecewise building of the proteobacterial histidine operonRenato Fani
Dipartimento di Biologia Animale e Genetica, Firenze, Italy
J Mol Evol 60:378-90. 2005The structure and organization of 470 histidine biosynthetic genes from 47 different proteobacteria were combined with phylogenetic inference to investigate the mechanisms responsible for assembly of the his pathway and the origin of his ..
- Profiling the secretomes of plant pathogenic ProteobacteriaGail M Preston
Department of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, UK
FEMS Microbiol Rev 29:331-60. 2005....
- Protein domains and architectural innovation in plant-associated ProteobacteriaDavid J Studholme
The Sainsbury Laboratory, Norwich, NR4 7UH, UK
BMC Genomics 6:17. 2005..This observation motivated an investigation of the relationship between an organism's lifestyle and the complement of domains and domain architectures found within its proteome...
- Purifying selection in mitochondria, free-living and obligate intracellular proteobacteriaLeila Mamirova
Institute for Information Transmission Problems RAS, Bolshoi Karetny pereulok 19, Moscow 127994, Russia
BMC Evol Biol 7:17. 2007..Here we analyze the influence of these two factors on the strength of the purifying selection in mitochondrial and proteobacterial orthologous genes taking into account the differences in the organism lifestyles...
- Potent cytotoxins produced by a microbial symbiont protect host larvae from predationNicole Lopanik
Graduate College of Marine Studies, University of Delaware, Lewes, DE 19958, USA
Oecologia 139:131-9. 2004....
- Selection for highly biased amino acid frequency in the TolA cell envelope protein of ProteobacteriaAlejandro P Rooney
Microbial Genomics and Bioprocessing Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, U S Department of Agriculture, 1815 North University Street, Peoria, IL 61604, USA
J Mol Evol 57:731-6. 2003..However, this study shows that selection has acted to maintain high levels of alanine and lysine in the TolA protein of Proteobacteria, which in turn has biased nucleotide composition in the corresponding tolA gene.
- DNA binding activity of the Escherichia coli nitric oxide sensor NorR suggests a conserved target sequence in diverse proteobacteriaNicholas P Tucker
John Innes Centre, Colney, Norwich, United Kingdom
J Bacteriol 186:6656-60. 2004..The derived consensus sequence for NorR binding sites was used to search for novel members of the E. coli NorR regulon and to show that NorR binding sites are partially conserved in other members of the proteobacteria.
- Polymorphic proteins of Chlamydia spp.--autotransporters beyond the ProteobacteriaI R Henderson
Division of Immunity and Infection, The Medical School, University of Birmingham, Edgbaston, B15 2TT, Birmingham, UK
Trends Microbiol 9:573-8. 2001..resemble members of the autotransporter family, and we suggest that they follow the same secretion pathway...
- Genomes in flux: the evolution of archaeal and proteobacterial gene contentBerend Snel
European Molecular Biology Laboratory, 69117 Heidelberg, Germany
Genome Res 12:17-25. 2002..Here we reconstruct the gene content of ancestral Archaea and Proteobacteria and quantify the processes connecting them to their present day representatives based on the distribution of ..
- Succinate:quinone oxidoreductases from epsilon-proteobacteriaC Roy D Lancaster
Max Planck Institute of Biophysics, Department of Molecular Membrane Biology, Frankfurt am Main, Germany
Biochim Biophys Acta 1553:84-101. 2002The epsilon-proteobacteria form a subdivision of the Proteobacteria including the genera Wolinella, Campylobacter, Helicobacter, Sulfurospirillum, Arcobacter and Dehalospirillum...
- Identification of a unique IAHP (IcmF associated homologous proteins) cluster in Vibrio cholerae and other proteobacteria through in silico analysisSoumita Das
Human Genetics and Genomics Group, Indian Institute of Chemical Biology, Calcutta, India
In Silico Biol 3:287-300. 2003..cholerae though the relative position of respective ORFs are the same. In other proteobacteria like M. loti, A. tumefaciens, P. aeruginosa and S...
- [Computer analysis of regulating metabolism of glycerol-3-phosphate in proteobacteria genome]L V Danilova
Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, 101447 Russia
Mol Biol (Mosk) 37:843-9. 2003..responsible for metabolism of glycerol and glycerol-3-phosphate in genomes of alpha-, beta-, and gamma-proteobacteria. New palindromic GlpR-binding signals were identified in gamma-proteobacteria; consensus sequences being ..
- OGtree: a tool for creating genome trees of prokaryotes based on overlapping genesLi Wei Jiang
Institute of Bioinformatics and Department of Biological Science and Technology, National Chiao Tung University, Hsinchu 300, Taiwan
Nucleic Acids Res 36:W475-80. 2008..OGtree is available online at http://bioalgorithm.life.nctu.edu.tw/OGtree/...
- Proteorhodopsin genes are distributed among divergent marine bacterial taxaJosé R de la Torre
Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, CA 95039, USA
Proc Natl Acad Sci U S A 100:12830-5. 2003..PR genes are distributed among a variety of divergent marine bacterial taxa, including both alpha- and gamma-proteobacteria. Our analyses also demonstrate the utility of cultivation-independent comparative genomic approaches for ..
- Amino acid sequences and distribution of high-potential iron-sulfur proteins that donate electrons to the photosynthetic reaction center in phototropic proteobacteriaG Van Driessche
Department of Biochemistry, Physiology and Microbiology, Laboratory for Protein Biochemistry and Protein Engineering, University of Ghent, 9000 Ghent, Belgium
J Mol Evol 57:181-99. 2003..between the cytochrome bc1 complex and the reaction-center bacteriochlorophyll in some species of phototrophic proteobacteria, a role traditionally assigned to cytochrome c2...
- Comparative genomics of regulation of fatty acid and branched-chain amino acid utilization in proteobacteriaAlexey E Kazakov
Institute for Information Transmission Problems, RAS, Moscow, Russia
J Bacteriol 191:52-64. 2009..to identify candidate transcriptional factors and DNA motifs that control ILV and FA utilization pathways in proteobacteria. The metabolic regulons were characterized based on the identification and comparison of candidate ..
- Culturable aerobic bacteria from the upstream region of a karst water rivuletSylvie Cousin
German Collection of Microorganisms and Cell Cultures GmbH DSMZ, Braunschweig, Germany
Int Microbiol 11:91-100. 2008..showed that the isolates included members of Bacteriodetes (especially the genus Flavobacterium) and Proteobacteria (mainly Pseudomonas and Stenotrophomonas)...
- A DNA element recognised by the molybdenum-responsive transcription factor ModE is conserved in Proteobacteria, green sulphur bacteria and ArchaeaDavid J Studholme
Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK
BMC Microbiol 3:24. 2003..In E. coli and other Proteobacteria molybdenum metabolism and homeostasis are regulated by the molybdate-responsive transcription factor ModE.
- Coexistence of multiple proteobacterial endosymbionts in the gills of the wood-boring Bivalve Lyrodus pedicellatus (Bivalvia: Teredinidae)Daniel L Distel
Department of Biochemistry, Microbiology, and Molecular Biology, University of Maine, Orono 04469, USA
Appl Environ Microbiol 68:6292-9. 2002..turnerae. Phylogenetic analyses indicate that the three newly detected ribotypes are derived from gamma proteobacteria that are related to but distinct (>6.5% sequence divergence) from T. turnerae...
- Structures of polysaccharides and oligosaccharides of some Gram-negative marine ProteobacteriaEvgeny L Nazarenko
Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, Vladivostok 690022, Russian Federation
Carbohydr Res 338:2449-57. 2003..the genera Pseudoalteromonas and Shewanella belonging to the Alteromonadaceae family and gamma-subclass of Proteobacteria, are reviewed. The polysaccharides are distinguished by the acidic character (e.g...
- Degradation of polycyclic aromatic hydrocarbons at low temperature under aerobic and nitrate-reducing conditions in enrichment cultures from northern soilsMikael Eriksson
Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
Appl Environ Microbiol 69:275-84. 2003..e., different species or subspecies). The composition of the enriched communities appeared to be more affected by presence of oxygen, than by temperature or source of the inoculum...
- Phylogenetic characterization of epibiotic bacteria in the accessory nidamental gland and egg capsules of the squid Loligo pealei (Cephalopoda:Loliginidae)E Barbieri
The Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, Woods Hole, MA 02543, USA
Environ Microbiol 3:151-67. 2001..hybridization (FISH) and 16S rDNA analysis showed that predominantly alpha- and, to a lesser extent, gamma-proteobacteria were the predominant components of the ANG and EC bacterial communities...
- Molecular ecology of nifH genes and transcripts in the eastern Mediterranean SeaDikla Man-Aharonovich
Faculty of Biology, Technion Israel Institute of Technology, Haifa 32000, Israel
Environ Microbiol 9:2354-63. 2007..We observed different nifH genes from diverse microbial groups, such as Cyanobacteria, Proteobacteria and methanogenic Archaea...
- Genome prediction of PhoB regulated promoters in Sinorhizobium meliloti and twelve proteobacteriaZe Chun Yuan
Center for Environmental Genomics, Department of Biology, McMaster University, Hamilton, Ontario, Canada, L8S 4K1
Nucleic Acids Res 34:2686-97. 2006In proteobacteria, genes whose expression is modulated in response to the external concentration of inorganic phosphate are often regulated by the PhoB protein which binds to a conserved motif (Pho box) within their promoter regions...
- Variation in M. tuberculosis in response to host selectionSarah Fortune; Fiscal Year: 2009..In these studies, we expect to provide fundamental insights into the mechanisms and targets of diversifying immune selection in M. tuberculosis. ..
- Optimized Growth Media to Detect Intracellular Bacteria Implicated in Chronic DisPATRICIA MASCARELLI; Fiscal Year: 2011..cornerstone of this molecular diagnostic platform is a patented pre-enrichment medium called Bartonella Alpha Proteobacteria Growth Medium (BAPGM). Galaxy Diagnostics holds an exclusive license on BAPGM...
- Characterization of a novel role for DEAD-box RNA helicases in bacteria.CHRISTOPHER ANTHONY VAKULSKAS; Fiscal Year: 2013..herein, has profound effects on biofilm formation, motility, and the expression of virulence factors in ?-proteobacteria. The proposed studies detail a plan to investigate the role of DEAD-box RNA helicases in Csr regulation...
- Coordination of metabolism and virulence during infectionTony Romeo; Fiscal Year: 2013..SirA and CsrA orthologs are highly conserved throughout the gamma-proteobacteria and are important for disease transmission and/or virulence in every species in which they have been examined...
- Small Regulatory RNAs of Coxiella burnetii - The Agent of Q FeverJAMES MICHAEL BATTISTI; Fiscal Year: 2013..Moreover, the results will clarify the rol of 6S sRNA in g-proteobacteria, where orthologous s factors play distinctive roles in different bacterial species.
- Bartonella: dissecting niche-specific adaptation in a human pathogenJane E Koehler; Fiscal Year: 2013..sigma factor gene homologous to the extracytoplasmic function (ECF) sigma factor of several alpha-proteobacteria, is significantly up-regulated at the 28[unreadable]C temperature of the arthropod vector...
- Genetic Approaches to Lipid MetabolismJohn E Cronan; Fiscal Year: 2013..coli and this pathway will be dissected. A third pathway to be studied is that found in the a-proteobacteria (e.g., Brucella) which seems a variation of the E. coli pathway...
- Host Cell JAK-STAT Activation and Pathogenesis of Spotted Fever RickettsiosesSanjeev K Sahni; Fiscal Year: 2012..conorii are Gram-negative, obligate intracellular a-proteobacteria known to cause Rocky Mountain spotted fever (RMSF) and Mediterranean SF in humans...
- Urease Activity and Nitrogen Assimilation in Helicobacter pyloriERICA FRANCESCA MILLER; Fiscal Year: 2012..pylori is not typical of other proteobacteria. In fact, H...
- Mass Spectrometric Characterization of LipopolysaccharidesJennifer S Brodbelt; Fiscal Year: 2013..forged between the Brodbelt and Trent groups is aimed at elucidating the LPS modification systems of three proteobacteria and elaborating their structure/function relationships...
- Regulation of Stationary Phase in Escherichia coliThomas J Silhavy; Fiscal Year: 2013..is the master regulator of stationary phase and the general stress response in Escherichia coli and many other proteobacteria. In rapidly growing cells, RpoS is made but it is degraded by the ClpX/P protease...
- Evasion of complement-mediated killing by pathogenic rickettsial speciesJuan J Martinez; Fiscal Year: 2013DESCRIPTION (provided by applicant): The Gram-negative [unreadable]-proteobacteria of the genus Rickettsia are small (0.3-0.5 x 0.8-1.0 ?m), obligate intracellular organisms...
- N-acetylglutamate Synthase: Structure, Function &DefectsMendel Tuchman; Fiscal Year: 2012..We found in a number of proteobacteria species (X. campestris, M. maris, O. alexandrii, X. axonopodis, and X...
- Integrating lipid biosynthesis with bacterial cell cycle progressionSean Murray; Fiscal Year: 2010..Most previous studies on bacterial lipid metabolism have focused on E. coli, a gamma-proteobacteria. Caulobacter in contrast, as an alpha-proteobacteria, is closely related to human pathogenic bacteria, such as ..
- Elucidation of a bacterial cell shape generating program and pathogenic functionsNINA REDA SALAMA; Fiscal Year: 2013..molecular determinants of helical cell shape and the selective role of shape during host colonization in the Proteobacteria;Csd proteins and CcmA homologues are well conserved among curved to helical Proteobacteria including several ..
- Subcellular architecture of regulatory protein complexes at the bacterial poleLUCILLE SHAPIRO; Fiscal Year: 2013..Much of the organization in ?-proteobacteria occurs in the cell pole, the anchor not only for the flagellum, but also for the chromosomal origin, the ..
- Therapeutic intervention for BrucellaAMY RAMBOW LARSEN; Fiscal Year: 2009..this goal, we have developed a peptide antibiotic, trifolitoxin (TFX), with activity against members of the ?-proteobacteria, especially Brucella...
- Regulation of intestinal barrier by E. coli curli fibrilsCagla Tukel; Fiscal Year: 2013..a common component of the biofilms of bacteria, are produced by the members of Bacteriodetes, Firmicutes and Proteobacteria. Recently, we have shown that curli, an amyloid found within the biofilms of enteric bacteria, is recognized ..
- Regulation of bacterial manganese metabolismMARK R O'BRIAN; Fiscal Year: 2013..coli and other model organisms. B. japonicum belongs to the alpha-Proteobacteria, a diverse taxonomic group that includes numerous members that form close or intracellular associations with ..
- Regulatory network of a conserved polar factor in Sinorhizobium melilotiJOSEPH CHIUNG CHU CHEN; Fiscal Year: 2013..Results from the investigation will help elucidate regulatory circuits that appear to be iterated in the alpha-proteobacteria group, which includes pathogens such as Brucella and Bartonella...
- Regulation of Bacterial Heme MetabolismMARK R O'BRIAN; Fiscal Year: 2012..Furthermore, Irr homologs are found in most [unreadable]-Proteobacteria, and thus the proposed work serves as a model for understanding heme and iron metabolism in pathogenic ..
- Defining AAA+ enzyme function in bacterial secretionADRIAN OTHONIEL OLIVARES; Fiscal Year: 2010..Interestingly, protein secretion by the type VI secretion system (T6SS) in pathogenic proteobacteria requires CIpV and appears to be tightly controlled by a novel serine-threonine kinase pathway recently ..
- Developmental Asymmetry in Agrobacterium tumefaciensJASON EUGENE HEINDL; Fiscal Year: 2013..Despite a high degree of conservation among the a-Proteobacteria, including A...
- Regulated Assembly of Subcellular Structures in alpha-ProteobacteriaJOSEPH CHIUNG CHU CHEN; Fiscal Year: 2010..Components of the pathway may serve as targets for new antimicrobial compounds. ..
- The mechanism of signal transduction in photoreceptorsHartmut Luecke; Fiscal Year: 2006..helix, retinylidene proteins found in phylogenetically diverse microorganisms, including haloarchaea, proteobacteria, cyanobacteria, fungi, and algae...
- The Role for NKAP in iNKT cell developmentVirginia Smith Shapiro; Fiscal Year: 2012..In addition to having an important role in the clearance of a subset of alpha-proteobacteria, iNKT cells have also been shown to regulate tumor surveillance and tumor rejection, autoimmune diseases, and ..
- Host-microbial interactions in the gut oxygen equilibriumGary D Wu; Fiscal Year: 2013..the well-described "dysbiotic" composition of the gut microbiome observed in IBD, with the bloom of aerobic Proteobacteria and Actinobacteria, is a response of the gut microbiota to higher pO2 levels and subsequent oxidative stress...
- INTERACTIONS BETWEEN AGROBACTERIUM AND HOST PLANTSStephen C Winans; Fiscal Year: 2010..Among these signals, acyl-homoserine lactones (AHLs) are especially widespread among the proteobacteria. AHLs are generally synthesized by proteins resembling the Luxl protein of Vibrio fischeri, and detected by ..
- Automated Simultaneous Detection of Bioterrorism AgentsDavid Ecker; Fiscal Year: 2005..Bunyaviridae, Flaviviridae, Togaviridae (especially VEE), and Filoviridea families and the alpha, beta, gamma-proteobacteria. To enable deployment at the CDC, the mass spectrometry detector must be developed on an inexpensive and small ..
- Intracellular screens discovery of natural products*(RMI)Jo Handelsman; Fiscal Year: 2007..We intend to develop expression systems in representatives of four diverse divisions of bacteria: Gamma-Proteobacteria (E...
- Quorum Sensing in Burkholderia malleiJosephine R Chandler; Fiscal Year: 2010..by acyl-homoserine lactone (acyl-HSL) quorum sensing (QS) is common to a variety of Gram-negative Proteobacteria and regulates diverse biological functions...
- Early Host Response Elicitation by AgrobacteriumMarion Brodhagen; Fiscal Year: 2004..mammalian cells, but is not universal, and iii) provide a basis for comparison of host responses to phylogenetically proximal members of the alpha-2 proteobacteria, which include plant symbionts and mammalian pathogens.
- Rapid Point-of-Care Diagnostic Test for ChlamydiaZihua Wang; Fiscal Year: 2004..Phase I, we propose to develop novel specific TaqMan probes which can differentiate CT from other bacteria or proteobacteria, and develop a rapid real-time PCR for CT detection within 15 minutes on our proprietary lab-in-a-tube ..
- International Symposium on the Comparative Biology of the Alpha-ProteobacteriaBruno Sobral; Fiscal Year: 2006..by applicant): Project Summary: The 2006 International Symposium on the Comparative Biology of the Alpha-Proteobacteria (NIH)...
- DNA Replication in B. subtilisCHARLES MCHENRY; Fiscal Year: 2006..from Proteobacteria and E. coli, ii. its genome has been sequenced and it has a developed genetic system, iii...
- Gene Expression Levels Across Diverse GenomesSamuel Karlin; Fiscal Year: 2006..The second group consists of all available high G+C a-proteobacteria. The latter genomes are important for understanding nitrogen fixation...
- MOLECULAR SEQUENCE DATASamuel Karlin; Fiscal Year: 2001..by spacings between repeats, and by properties of repeat families (intergenic, coding, direct, inverted, mixed). ..
- GENETIC CONTROL OF NITRATE RESPIRATION IN E. COLIValley J Stewart; Fiscal Year: 2010..The Nar regulatory network is unique to enterobacteria;other species of proteobacteria (including several human pathogens) contain only the NarQ-NarP system (e.g...
- PROTEIN-MINERAL INTERACTIONS AND CALCIUM OXALATE STONESROSEMARY RYALL; Fiscal Year: 2008..abstract_text> ..
- DNA METHYLATION AND PILI GENE REGULATIONDavid Low; Fiscal Year: 2006..These studies will also provide a detailed framework for understanding epigenetic regulatory mechanisms in other prokaryotes and eukaryotes. ..
- Sixth International Conference on LegionellaNicholas Cianciotto; Fiscal Year: 2005..This unique gathering of microbiologists, physicians, public health officials, and engineers is the definitive meeting for those concerned with Legionella and its associated diseases. ..
- Bacterial flora in normal esophagus & reflux disordersZhiheng Pei; Fiscal Year: 2005..ii) While GERD initially results from chemical damage, bacterial overgrowth may promote intestinal metaplasia of the esophagus. The proposed study allows qualitative and quantitative examination of this hypothesis. ..
- Gene Duplication and Genome EvolutionAustin Hughes; Fiscal Year: 2004..5) Examining the role of transposable elements in duplication of genomic segments by testing for nonrandom association between these elements and putatively duplicated blocks in the yeast genome. ..
- Cryptosporidium parvum DNA replication proteinsGuan Zhu; Fiscal Year: 2004..The completion of these aims will not only prove or refute our hypothesis, but also establish a new foundation for the drug discovery targeting the parasite unique DNA mechanism machinery. ..
- CULTIVABLE & UNCULTIVABLE PERIODONTAL SPIROCHETESFloyd Dewhirst; Fiscal Year: 2003..abstract_text> ..
- Protein targeting and secretion in ToxoplasmaBoris Striepen; Fiscal Year: 2004..Mutant analysis will also provide critical information towards the function of the individual secretory organelles involved. ..
- BIOCHEMICAL CYTOLOGY OF ANAEROBIC PARASITIC PROTISTSMIKLOS MULLER; Fiscal Year: 2003..b ) Enzymes transferring reducing equivalents from glycolytically reduced NADH and ferredoxin to diverse electron acceptors and O2 will be explored with essentially the same approaches. ..
- Support for 2002 GRC on Photosensory Receptors & SignalJohn Spudich; Fiscal Year: 2002..We expect the conference will stimulate exciting discussion of emerging insights, general principles, and the most engaging mysteries on the cutting edge of photosensory signal transduction. ..
- Transcriptional Profiles of Escherichia coli BiofilmsRobert McLean; Fiscal Year: 2002..Overall, this project will explain several fundamental aspects of E. coli biofilm growth and suggest possible targets for future antibiotic research. ..
- MOLECULAR STRUCTURE OF STEROIDSWilliam Duax; Fiscal Year: 2006..Proof of the successful prediction of the structures of 20-30 hypothetical members of the SCOR proteome could provide a model for the prediction of protein folding on the basis of as little as 20% sequence homology. ..
- Proteomic determination of arsenical actionPartha Basu; Fiscal Year: 2005..These studies will greatly expand the understanding of the biochemical activation of vascular cell signaling that is relevant to arsenic-related vascular diseases. ..
- EVOLUTION OF IMMUNE RECOGNITION AND EVASIONAustin L Hughes; Fiscal Year: 2010..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
- Impact of Social Stress on TLR4-Induced Microbicidal Activity of CD11b+ CellsMichael Bailey; Fiscal Year: 2008..Defining the stress-induced cellular changes that enhance immune functioning could stimulate new therapeutic approaches to treating infectious diseases. [unreadable] [unreadable] [unreadable] [unreadable]..
- IMPDH as a Drug Target in CryptosporidiumBoris Striepen; Fiscal Year: 2008..This work will provide urgently needed molecular reagents to understand the biology of nutrient uptake and drug resistance in this unique parasite. [unreadable] [unreadable] [unreadable]..
- Ninth International Congress on ToxoplasmosisBoris Striepen; Fiscal Year: 2007..gondii that is not often seen in fields as high paced and[unreadable] competitive and has facilitated rapid and sustained progress in research on this pathogen[unreadable] and related parasites. ..
- Chemoenzymatic analysis of bryostatin biosynthesisNicole Lopanik; Fiscal Year: 2007..This research may lead to production of bryostatin by a heterologous host. ..
- Structure of the Survival Motor Neuron Protein (SMN)James Allen; Fiscal Year: 2006..Together, these results should enhance our understanding of the molecular reasons for SMA and potentially lead to new strategies for the development of therapies. ..
- Eukaryotic Membrane Protein Folding in E. coliJohn Spudich; Fiscal Year: 2006..Submitted in response to PA-03-100 High Impact/High Risk Research and PA-02-060 Structural Biology of Membrane Proteins. ..
- EVOLUTIONARY GENETICS OF MALE REPRODUCTIVE TRAITS IN MUSMATTHEW DEAN; Fiscal Year: 2006..These studies will help uncover the genetic basis of male reproductive fitness in a natural population of house mice. [unreadable] [unreadable]..
- Structure-Function of Borrelia Surface LipoproteinsWOLFRAM ZUECKERT; Fiscal Year: 2005..Furthermore, they will yield important clues for the design of future intervention strategies. ..
- Lipoprotein Transport in Borrelia SpirochetesWOLFRAM R ZUECKERT; Fiscal Year: 2010....
- Butane metabolism in Pseudomonas butanovoraDaniel Arp; Fiscal Year: 2006..Studies of parallel pathways will be relevant to other metabolic pathways where toxic metabolites are necessarily produced as part of the metabolism of a growth supporting substrate. ..
- A Novel Virus that Infects & Sterilizes Insect Vectors of Human DiseaseDrion Boucias; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..