staphylococcus

Summary

Summary: A genus of gram-positive, facultatively anaerobic, coccoid bacteria. Its organisms occur singly, in pairs, and in tetrads and characteristically divide in more than one plane to form irregular clusters. Natural populations of Staphylococcus are membranes of warm-blooded animals. Some species are opportunistic pathogens of humans and animals.

Top Publications

  1. pmc Combination of multiplex PCRs for staphylococcal cassette chromosome mec type assignment: rapid identification system for mec, ccr, and major differences in junkyard regions
    Yoko Kondo
    Department of Infection Control Science, Juntendo University, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Antimicrob Agents Chemother 51:264-74. 2007
  2. pmc The intercellular adhesion (ica) locus is present in Staphylococcus aureus and is required for biofilm formation
    S E Cramton
    Mikrobielle Genetik, Universitat Tubingen, D 72076 Tubingen, Germany
    Infect Immun 67:5427-33. 1999
  3. doi Methicillin-resistant Staphylococcus aureus and Staphylococcus pseudintermedius in veterinary medicine
    J Scott Weese
    Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, N1G2W1, Canada
    Vet Microbiol 140:418-29. 2010
  4. ncbi Gene replacement in Staphylococcus carnosus and Staphylococcus xylosus
    R Bruckner
    Mikrobielle Genetik, Universitat Tubingen, Germany
    FEMS Microbiol Lett 151:1-8. 1997
  5. doi Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materials
    Carla Renata Arciola
    Research Unit on Implant Infections, Rizzoli Orthopaedic Institute, Via Di Barbiano 1 10, 40136 Bologna, Italy
    Biomaterials 33:5967-82. 2012
  6. pmc Identification of a plasmid-borne chloramphenicol-florfenicol resistance gene in Staphylococcus sciuri
    S Schwarz
    Institut für Tierzucht und Tierverhalten der Bundesforschungsanstalt für Landwirtschaft Braunschweig FAL, Celle, Germany
    Antimicrob Agents Chemother 44:2530-3. 2000
  7. pmc Population genetic structure of the Staphylococcus intermedius group: insights into agr diversification and the emergence of methicillin-resistant strains
    Jeanette Bannoehr
    Laboratory for Bacterial Evolution and Pathogenesis, Centre for Infectious Diseases, The Chancellor s Building, New Royal Infirmary, University of Edinburgh, Edinburgh EH16 4SB, Scotland
    J Bacteriol 189:8685-92. 2007
  8. doi Review on methicillin-resistant Staphylococcus pseudintermedius
    Engeline van Duijkeren
    Faculty of Veterinary Medicine, Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands
    J Antimicrob Chemother 66:2705-14. 2011
  9. doi Risk of colonization or gene transfer to owners of dogs with meticillin-resistant Staphylococcus pseudintermedius
    Linda A Frank
    Department of Small Animal Clinical Sciences, University of Tennessee, Knoxville, TN 37996 4544, USA
    Vet Dermatol 20:496-501. 2009
  10. doi Role of coagulase-negative staphylococci in human disease
    A Piette
    Department of Microbiology, University Hospital Ghent, De Pintelaan 185, 9000 Ghent, Belgium
    Vet Microbiol 134:45-54. 2009

Detail Information

Publications381 found, 100 shown here

  1. pmc Combination of multiplex PCRs for staphylococcal cassette chromosome mec type assignment: rapid identification system for mec, ccr, and major differences in junkyard regions
    Yoko Kondo
    Department of Infection Control Science, Juntendo University, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Antimicrob Agents Chemother 51:264-74. 2007
    Staphylococcal cassette chromosome mec (SCCmec) typing, in combination with genotyping of the Staphylococcus aureus chromosome, has become essential for defining methicillin-resistant S. aureus (MRSA) clones in epidemiological studies...
  2. pmc The intercellular adhesion (ica) locus is present in Staphylococcus aureus and is required for biofilm formation
    S E Cramton
    Mikrobielle Genetik, Universitat Tubingen, D 72076 Tubingen, Germany
    Infect Immun 67:5427-33. 1999
    ..implants are a leading cause of sepsis and are often associated with colonization of the implants by Staphylococcus epidermidis...
  3. doi Methicillin-resistant Staphylococcus aureus and Staphylococcus pseudintermedius in veterinary medicine
    J Scott Weese
    Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, N1G2W1, Canada
    Vet Microbiol 140:418-29. 2010
    ..Among the most relevant species are the coagulase positive species Staphylococcus aureus and Staphylococcus pseudintermedius...
  4. ncbi Gene replacement in Staphylococcus carnosus and Staphylococcus xylosus
    R Bruckner
    Mikrobielle Genetik, Universitat Tubingen, Germany
    FEMS Microbiol Lett 151:1-8. 1997
    A system for high-efficiency gene replacement in Staphylococcus carnosus and Staphylococcus xylosus has been developed, that is based on temperature-sensitive Escherichia coli-Staphylococcus shuttle vectors for fragment delivery and ..
  5. doi Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materials
    Carla Renata Arciola
    Research Unit on Implant Infections, Rizzoli Orthopaedic Institute, Via Di Barbiano 1 10, 40136 Bologna, Italy
    Biomaterials 33:5967-82. 2012
    ..Latter approaches appear promising, since they avoid the spread of antibacterial substances in the neighbouring tissues with the consequent risk of inducing bacterial resistance...
  6. pmc Identification of a plasmid-borne chloramphenicol-florfenicol resistance gene in Staphylococcus sciuri
    S Schwarz
    Institut für Tierzucht und Tierverhalten der Bundesforschungsanstalt für Landwirtschaft Braunschweig FAL, Celle, Germany
    Antimicrob Agents Chemother 44:2530-3. 2000
    The 16.5-kbp plasmid pSCFS1 from Staphylococcus sciuri mediated combined resistance to chloramphenicol and florfenicol. The gene responsible for this resistance property, cfr, was cloned and sequenced...
  7. pmc Population genetic structure of the Staphylococcus intermedius group: insights into agr diversification and the emergence of methicillin-resistant strains
    Jeanette Bannoehr
    Laboratory for Bacterial Evolution and Pathogenesis, Centre for Infectious Diseases, The Chancellor s Building, New Royal Infirmary, University of Edinburgh, Edinburgh EH16 4SB, Scotland
    J Bacteriol 189:8685-92. 2007
    The population genetic structure of the animal pathogen Staphylococcus intermedius is poorly understood...
  8. doi Review on methicillin-resistant Staphylococcus pseudintermedius
    Engeline van Duijkeren
    Faculty of Veterinary Medicine, Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands
    J Antimicrob Chemother 66:2705-14. 2011
    b>Staphylococcus pseudintermedius is an important opportunistic pathogen of companion animals, especially dogs. Since 2006 there has been a significant emergence of methicillin-resistant S...
  9. doi Risk of colonization or gene transfer to owners of dogs with meticillin-resistant Staphylococcus pseudintermedius
    Linda A Frank
    Department of Small Animal Clinical Sciences, University of Tennessee, Knoxville, TN 37996 4544, USA
    Vet Dermatol 20:496-501. 2009
    ..Cultures were obtained from the dog's lesions and the owner's nasal cavity on the initial visit. Staphylococcus isolates were identified and antimicrobial susceptibility tests were performed by the Kirby-Bauer disk ..
  10. doi Role of coagulase-negative staphylococci in human disease
    A Piette
    Department of Microbiology, University Hospital Ghent, De Pintelaan 185, 9000 Ghent, Belgium
    Vet Microbiol 134:45-54. 2009
    ..In the immunocompetent host, CNS endocarditis and urinary tract infections with Staphylococcus saprophyticus are the most common CNS infections...
  11. ncbi Optimization of electroporation-mediated transformation: Staphylococcus carnosus as model organism
    J Löfblom
    Department of Molecular Biotechnology, School of Biotechnology, Royal Institute of Technology KTH, AlbaNova University Center, Stockholm, Sweden
    J Appl Microbiol 102:736-47. 2007
    The study was conducted with an aim to optimize the transformation efficiency of the Gram-positive bacterium Staphylococcus carnosus to a level that would enable the creation of cell surface displayed combinatorial protein libraries.
  12. ncbi Quantification of biofilm in microtiter plates: overview of testing conditions and practical recommendations for assessment of biofilm production by staphylococci
    Srdjan Stepanovic
    Department of Bacteriology, Institute of Microbiology and Immunology, School of Medicine, Belgrade, Serbia
    APMIS 115:891-9. 2007
    ..The obtained results should simplify quantification of biofilm formation in microtiter plates, and make it more reliable and comparable among different laboratories...
  13. pmc Efficacy of clarithromycin on biofilm formation of methicillin-resistant Staphylococcus pseudintermedius
    Matthew Dicicco
    School of Engineering, University of Guelph, Ontario, Canada
    BMC Vet Res 8:225. 2012
    Surgical site infections (SSIs) caused by biofilm-forming methicillin-resistant Staphylococcus pseudintermedius (MRSP) have emerged as the most common hospital-acquired infections in companion animals...
  14. doi Characterization of methicillin-resistant Staphylococcus spp. carrying the mecC gene, isolated from wildlife
    Igor Loncaric
    Institute of Bacteriology, Mycology and Hygiene, University of Veterinary Medicine, Veterinarplatz 1, A 1210 Vienna, Austria
    J Antimicrob Chemother 68:2222-5. 2013
    A recently identified mecA homologue, mecC, in methicillin-resistant Staphylococcus aureus (MRSA) has been isolated from humans and different animal hosts...
  15. pmc First case of Staphylococcus pseudintermedius infection in a human
    Lieve Van Hoovels
    Department of Clinical Microbiology, OLV Hospital, Moorselbaan 164, B 9300 Aalst, Belgium
    J Clin Microbiol 44:4609-12. 2006
    We present the first clinical report of a Staphylococcus pseudintermedius infection in a human. Biochemically, S. pseudintermedius can be easily misidentified as S. aureus...
  16. pmc Complete genome sequence of Staphylococcus lugdunensis strain HKU09-01
    Herman Tse
    Carol Yu Centre for Infection, Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong
    J Bacteriol 192:1471-2. 2010
    b>Staphylococcus lugdunensis is a member of the coagulase-negative staphylococci and commonly found as part of the human skin flora...
  17. pmc Origin and molecular evolution of the determinant of methicillin resistance in staphylococci
    Sae Tsubakishita
    Department of Infection Control Science, Juntendo University, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Antimicrob Agents Chemother 54:4352-9. 2010
    Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most important multidrug-resistant pathogens around the world. MRSA is generated when methicillin-susceptible S...
  18. doi Coagulase-negative staphylococcal infections
    Kathie L Rogers
    Department of Pathology and Microbiology, University of Nebraska Medical Center, 986280 Nebraska Medical Center, Omaha, NE 68198 6280, USA
    Infect Dis Clin North Am 23:73-98. 2009
    Coagulase-negative staphylococci (CNS) are differentiated from the closely related but more virulent Staphylococcus aureus by their inability to produce free coagulase. Currently, there are over 40 recognized species of CNS...
  19. pmc Glycerol monolaurate and dodecylglycerol effects on Staphylococcus aureus and toxic shock syndrome toxin-1 in vitro and in vivo
    Ying Chi Lin
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, USA
    PLoS ONE 4:e7499. 2009
    Glycerol monolaurate (GML), a 12 carbon fatty acid monoester, inhibits Staphylococcus aureus growth and exotoxin production, but is degraded by S. aureus lipase...
  20. ncbi Cellular invasion by Staphylococcus aureus reveals a functional link between focal adhesion kinase and cortactin in integrin-mediated internalisation
    Franziska Agerer
    Zentrum für Infektionsforschung, Universitat Wurzburg, Rontgenring 11, 97070 Wurzburg, Germany
    J Cell Sci 118:2189-200. 2005
    Nosocomial infections by Staphylococcus aureus, a Gram-positive pathogen colonising human skin and mucosal surfaces, are an increasing health care problem...
  21. pmc Genome analysis of the meat starter culture bacterium Staphylococcus carnosus TM300
    Ralf Rosenstein
    Mikrobielle Genetik, Eberhard Karls Universitat Tubingen, Germany
    Appl Environ Microbiol 75:811-22. 2009
    The Staphylococcus carnosus genome has the highest GC content of all sequenced staphylococcal genomes, with 34.6%, and therefore represents a species that is set apart from S. aureus, S. epidermidis, S. saprophyticus, and S. haemolyticus...
  22. pmc Genetic classification and distinguishing of Staphylococcus species based on different partial gap, 16S rRNA, hsp60, rpoB, sodA, and tuf gene sequences
    B Ghebremedhin
    Otto von Guericke University, Clinical Microbiology, Leipziger Str 44, Magdeburg, Germany
    J Clin Microbiol 46:1019-25. 2008
    ..Thus, new phylogenetic markers for Staphylococcus spp. are needed...
  23. pmc Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection
    Makoto Kuroda
    Department of Microbiology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Tsukuba, Ibaraki 305 8575, Japan
    Proc Natl Acad Sci U S A 102:13272-7. 2005
    b>Staphylococcus saprophyticus is a uropathogenic Staphylococcus frequently isolated from young female outpatients presenting with uncomplicated urinary tract infections. We sequenced the whole genome of S...
  24. ncbi Coagulase-negative staphylococci: role as pathogens
    J Huebner
    Dept of Infectious Diseases, Children s Hospital, Boston, Massachusetts, USA
    Annu Rev Med 50:223-36. 1999
    ..Although specific virulence factors are not as clearly established as they are in Staphylococcus aureus, it seems clear that factors such as bacterial polysaccharide components are involved in attachment and/..
  25. pmc Characterization of the biofilm forming ability of Staphylococcus pseudintermedius from dogs
    Ameet Singh
    Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada
    BMC Vet Res 9:93. 2013
    b>Staphylococcus pseudintermedius is an opportunistic pathogen of dogs and has emerged as a leading cause of skin, wound and surgical site infections worldwide...
  26. doi Treatment outcome of dogs with meticillin-resistant and meticillin-susceptible Staphylococcus pseudintermedius pyoderma
    Jacqueline Bryan
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996, USA
    Vet Dermatol 23:361-8, e65. 2012
    The prevalence of meticillin- and multidrug-resistant Staphylococcus pseudintermedius (MRSP) in canine pyoderma has been increasing in recent years; thus, treatment of these cases has become challenging.
  27. pmc Poly-N-acetylglucosamine is not a major component of the extracellular matrix in biofilms formed by icaADBC-positive Staphylococcus lugdunensis isolates
    Kristi L Frank
    Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Infect Immun 75:4728-42. 2007
    b>Staphylococcus lugdunensis is a pathogen of heightened virulence that causes infections resembling those caused by Staphylococcus aureus rather than those caused by its coagulase-negative staphylococcal counterparts. Many types of S...
  28. ncbi Evaluation of susceptibility test breakpoints used to predict mecA-mediated resistance in Staphylococcus pseudintermedius isolated from dogs
    David A Bemis
    Department of Comparative Medicine, College of Veterinary Medicine, The University of Tennessee, Knoxville, TN 37901 1071, USA
    J Vet Diagn Invest 21:53-8. 2009
    ..interpretive breakpoints for in vitro susceptibility tests that predict mecA-mediated oxacillin resistance in Staphylococcus pseudintermedius isolates from animals have been changed twice in the past decade...
  29. doi Clonal diversity and biofilm-forming ability of methicillin-resistant Staphylococcus pseudintermedius
    Ane Mohr Osland
    Section for Bacteriology Aquatic and Terrestrial, Norwegian Veterinary Institute, PO Box 750 Sentrum, N 0106 Oslo, Norway
    J Antimicrob Chemother 67:841-8. 2012
    The aim of this study was to investigate the clonal epidemiology of methicillin-resistant Staphylococcus pseudintermedius (MRSP) isolates from dogs in Norway and to evaluate the antimicrobial resistance patterns and determine the biofilm-..
  30. doi A review of multidrug resistant surgical site infections
    J S Weese
    Department of Pathobiology, Ontario Veterinary College, University of Guelp, Guelp, Ontario, Canada
    Vet Comp Orthop Traumatol 21:1-7. 2008
    ..Despite the negative connotations that are associated with multi-drug resistant infections, most infections are potentially treatable if basic principles of infection treatment and infection control are followed...
  31. pmc High genetic variability of the agr locus in Staphylococcus species
    Philippe Dufour
    Centre Nationale des Toxémies à Staphylococques, EA1655, Faculte de Medecine Laennec, Lyon, France
    J Bacteriol 184:1180-6. 2002
    The agr quorum-sensing and signal transduction system was initially described in Staphylococcus aureus, where four distinct allelic variants have been sequenced...
  32. pmc Complete genome sequence of the veterinary pathogen Staphylococcus pseudintermedius strain HKU10-03, isolated in a case of canine pyoderma
    Herman Tse
    Carol Yu Centre for Infection, Department of Microbiology, 4 F University Pathology Building, Queen Mary Hospital, Pokfulam Road, Hong Kong SAR, China
    J Bacteriol 193:1783-4. 2011
    b>Staphylococcus pseudintermedius is a member of the coagulase-positive staphylococci and is the commonest cause of canine pyoderma. We report the first genome sequence of S...
  33. doi Microbiological and molecular characterization of human clinical isolates of Staphylococcus cohnii, Staphylococcus hominis, and Staphylococcus sciuri
    Elvira Garza-Gonzalez
    Departamento de Microbiologia, Facultad de Medicina, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico
    Scand J Infect Dis 43:930-6. 2011
    ..aim of this study was to characterize biofilm formation, antibiotic resistance, SCCmec type, and genetic relatedness in clinical isolates of Staphylococcus cohnii, Staphylococcus hominis, and Staphylococcus sciuri recovered from humans.
  34. pmc Diversity of SCCmec elements in methicillin-resistant coagulase-negative staphylococci clinical isolates
    Zhiyong Zong
    Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China
    PLoS ONE 6:e20191. 2011
    ..Characterization of SCCmec in MR-CoNS can generate useful information on the mobilization and evolution of this element...
  35. pmc Biofilm development by clinical isolates of Staphylococcus spp. from retrieved orthopedic prostheses
    Jaime Esteban
    Departments of Clinical Microbiology, Fundación Jiménez Díaz UTE, Madrid, Spain
    Acta Orthop 81:674-9. 2010
    ..Biofilms are considered the key factor in the development of implant-related infections. However, only a few reports have dealt with the ability of organisms isolated from such infections to develop biofilms in vitro...
  36. doi Household transmission of meticillin-resistant Staphylococcus aureus and other staphylococci
    Meghan F Davis
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lancet Infect Dis 12:703-16. 2012
    Although the role of pets in household transmission of meticillin-resistant Staphylococcus aureus (MRSA) has been examined previously, only minor attention has been given to the role of the abiotic household environment independent of, or ..
  37. ncbi Staphylococcus aureus adhesion to different treated titanium surfaces
    L G Harris
    AO Research Institute, Clavadelerstrasse, CH7270 Davos Platz, Switzerland
    J Mater Sci Mater Med 15:311-4. 2004
    b>Staphylococcus aureus is a major pathogen, associated with medical-device related infections. Converting biomaterial surfaces into non-interactive surfaces requires a specific surface/interface design...
  38. doi Preeminence of Staphylococcus aureus in infective endocarditis: a 1-year population-based survey
    Christine Selton-Suty
    Cardiologie, Centre Hospitalier Universitaire, Nancy, France
    Clin Infect Dis 54:1230-9. 2012
    ..We conducted a population-based study to control for this referral bias. The objective was to update the description of characteristics of IE in France and to compare the profile of community-acquired versus healthcare-associated IE...
  39. pmc Intrinsic novobiocin resistance in Staphylococcus saprophyticus
    Anna A Vickers
    Antimicrobial Research Centre and Research Institute of Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom
    Antimicrob Agents Chemother 51:4484-5. 2007
    Intrinsic novobiocin resistance in Staphylococcus saprophyticus was associated with expression of a novobiocin-resistant form of the drug target protein (GyrB)...
  40. ncbi Surveillance of healthy cats and cats with inflammatory skin disease for colonization of the skin by methicillin-resistant coagulase-positive staphylococci and Staphylococcus schleiferi ssp. schleiferi
    Jill L Abraham
    Department of Clinical Studies, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA
    Vet Dermatol 18:252-9. 2007
    ..of carriage and relative frequency of methicillin resistance in coagulase-positive staphylococci and Staphylococcus schleiferi ssp. schleiferi...
  41. pmc Diversity of Staphylococcus species strains based on partial kat (catalase) gene sequences and design of a PCR-restriction fragment length polymorphism assay for identification and differentiation of coagulase-positive species (S. aureus, S. delphini, S.
    Giuseppe Blaiotta
    Department of Food Science, School of Agriculture, University of Naples Federico II, Via Universita 100, 80055 Portici, Italy
    J Clin Microbiol 48:192-201. 2010
    ..In some strains of Staphylococcus xylosus, S. saprophyticus, and S. equorum, two catalase genes, katA and katB, were found...
  42. pmc Acceleration of the direct identification of Staphylococcus aureus versus coagulase-negative staphylococci from blood culture material: a comparison of six bacterial DNA extraction methods
    A J M Loonen
    PAMM Laboratory for Medical Microbiology, Eindhoven Veldhoven, The Netherlands
    Eur J Clin Microbiol Infect Dis 30:337-42. 2011
    To accelerate differentiation between Staphylococcus aureus and coagulase-negative staphylococci (CNS), this study aimed to compare six different DNA extraction methods from two commonly used blood culture materials, i.e...
  43. doi Identification of a novel Staphylococcus pseudintermedius exfoliative toxin gene and its prevalence in isolates from canines with pyoderma and healthy dogs
    Keita Iyori
    Tokyo University of Agriculture and Technology, Japan
    FEMS Microbiol Lett 312:169-75. 2010
    ..Recently, an exfoliative toxin gene (exi) was identified in Staphylococcus pseudintermedius isolated from canine pyoderma...
  44. pmc Coagulase-negative staphylococcal infections in the neonatal intensive care unit
    Naomi Jean-Baptiste
    Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    Infect Control Hosp Epidemiol 32:679-86. 2011
    ..Coagulase-negative staphylococci (CoNS) are the most commonly isolated pathogens in the neonatal intensive care unit (NICU). CoNS infections are associated with increased morbidity, including neurodevelopmental impairment...
  45. pmc Methicillin-resistant Staphylococcus pseudintermedius in a veterinary teaching hospital
    Takashi Sasaki
    Department of Infection Control Science, Faculty of Medicine, Juntendo University, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    J Clin Microbiol 45:1118-25. 2007
    We surveyed methicillin-resistant coagulase-positive staphylococcus (MRCPS) strains from 57 (26 inpatient and 31 outpatient) dogs and 20 veterinary staff in a veterinary teaching hospital...
  46. pmc Occurrence and molecular characteristics of methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus pseudintermedius in an academic veterinary hospital
    Kanako Ishihara
    School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi Bunkyodai Ebetsu, Hokkaido 069 8501, Japan
    Appl Environ Microbiol 76:5165-74. 2010
    Recently, methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus pseudintermedius (MRSP) have been increasingly isolated from veterinarians and companion animals...
  47. pmc Catheter-related bacteremia caused by Staphylococcus pseudintermedius refractory to antibiotic-lock therapy in a hemophilic child with dog exposure
    Chia Yunn Chuang
    Departments of Pediatrics, Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan
    J Clin Microbiol 48:1497-8. 2010
    We describe a case of catheter-related bacteremia due to Staphylococcus pseudintermedius in a child with dog exposure. The organism was confirmed as S...
  48. doi Beware of the pet dog: a case of Staphylococcus intermedius infection
    Russell Kempker
    Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA
    Am J Med Sci 338:425-7. 2009
    b>Staphylococcus intermedius is a common commensal and pathogen in dogs and cats and only rarely has been identified as causing human infection. We report a human case of postoperative sinus infection caused by methicillin-resistant S...
  49. doi Transmission of methicillin-resistant Staphylococcus intermedius between humans and animals
    E van Duijkeren
    Vet Microbiol 128:213-5. 2008
  50. doi Coagulase-negative staphylococci as cause of bovine mastitis- not so different from Staphylococcus aureus?
    Suvi Taponen
    University of Helsinki, Department of Production Animal Medicine, Helsinki, Finland
    Vet Microbiol 134:29-36. 2009
    In this review of the literature, mastitis-causing coagulase-negative staphylococci (CNS) and Staphylococcus aureus are compared...
  51. doi Species identification of coagulase-negative staphylococci: genotyping is superior to phenotyping
    Ruth N Zadoks
    Quality Milk Production Services, Cornell University, Ithaca, NY, USA
    Vet Microbiol 134:20-8. 2009
    ....
  52. doi Identification and characterization of methicillin-resistant coagulase-negative staphylococci from bovine mastitis
    Andrea T Fessler
    Institute of Farm Animal Genetics, Friedrich Loeffler Institut FLI, Neustadt Mariensee, Germany
    J Antimicrob Chemother 65:1576-82. 2010
    ....
  53. pmc A Staphylococcus xylosus isolate with a new mecC allotype
    Ewan M Harrison
    University of Cambridge, Department of Veterinary Medicine, Cambridge, United Kingdom
    Antimicrob Agents Chemother 57:1524-8. 2013
    Recently, a novel variant of mecA known as mecC (mecA(LGA251)) was identified in Staphylococcus aureus isolates from both humans and animals...
  54. pmc Quorum sensing in Staphylococcus infections
    Jeremy M Yarwood
    Department of Microbiology, University of Iowa Roy J and Lucille A Carver College of Medicine, 540 Eckstein Medical Research Building, 500 Newton Road, Iowa City, Iowa 52242, USA
    J Clin Invest 112:1620-5. 2003
    ..regulator (agr) system has been assigned a central role in the pathogenesis of staphylococci, particularly Staphylococcus aureus...
  55. pmc Characterization of new staphylococcal cassette chromosome mec (SCCmec) and topoisomerase genes in fluoroquinolone- and methicillin-resistant Staphylococcus pseudintermedius
    Sybill Descloux
    Institute of Veterinary Bacteriology, University of Bern, Langgass strasse 122, Postfach, CH 3001 Bern, Switzerland
    J Clin Microbiol 46:1818-23. 2008
    Fluoroquinolone- and methicillin-resistant Staphylococcus pseudintermedius isolates harbor two new staphylococcal cassette chromosome mec (SCCmec) elements that belong to class A, allotype 3 (SCCmec II-III), and to the new allotype 5 (..
  56. pmc Longitudinal shift in diabetic wound microbiota correlates with prolonged skin defense response
    Elizabeth A Grice
    Genetics and Molecular Biology Branch, National Institutes of Health Intramural Sequencing Center, National Human Geome Research Institute, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 107:14799-804. 2010
    ..Further, we establish a correlation between relative abundance of Staphylococcus spp. and the expression of cutaneous defense response genes...
  57. pmc Role of the twin-arginine translocation pathway in Staphylococcus
    Lalitha Biswas
    Mikrobielle Genetik, Universitat Tubingen, Tubingen, Germany
    J Bacteriol 191:5921-9. 2009
    In Staphylococcus, the twin-arginine translocation (Tat) pathway is present only in some species and is composed of TatA and TatC...
  58. pmc Vancomycin resistance in staphylococci
    Arjun Srinivasan
    Division of Infectious Diseases, Department of Internal Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Clin Microbiol Rev 15:430-8. 2002
    Vancomycin resistance has been reported in clinical isolates of both coagulase-negative staphylococci and Staphylococcus aureus...
  59. pmc Development of a PCR assay for identification of staphylococci at genus and species levels
    F Martineau
    , Sainte-Foy, , Canada GIV 4G2
    J Clin Microbiol 39:2541-7. 2001
    ..This sequence information allowed the development of Staphylococcus-specific and species-specific (targeting S. aureus, S. epidermidis, S. haemolyticus, S. hominis, or S...
  60. doi Coagulase-negative staphylococci-emerging mastitis pathogens
    Satu Pyörälä
    University of Helsinki, Department of Production Animal Medicine, FI 04920 Saarentaus, Finland
    Vet Microbiol 134:3-8. 2009
    ..CNS infection can damage udder tissue and lead to decreased milk production. Staphylococcus simulans and Staphylococcus chromogenes are currently the predominant CNS species in bovine mastitis. S...
  61. ncbi Methicillin-resistant staphylococcal colonization in clinically normal dogs and horses in the community
    M Vengust
    Veterinary Faculty, University of Ljubljana, Ljubljana, Slovenia
    Lett Appl Microbiol 43:602-6. 2006
    ..To evaluate the prevalence of methicillin-resistant staphylococcal (MRS) colonization in clinically normal dogs and horses in the community...
  62. ncbi The prevalence of methicillin-resistant staphylococci in healthy horses in the Netherlands
    J F Busscher
    Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands
    Vet Microbiol 113:131-6. 2006
    ..All isolates were coagulase negative staphylococci, except for one methicillin-resistant Staphylococcus aureus isolated from a veterinarian...
  63. doi Epitope mapping of antibodies using bacterial surface display
    Johan Rockberg
    Department of Molecular Biotechnology, School of Biotechnology, Royal Institute of Technology KTH, AlbaNova University Center, SE 106 91 Stockholm, Sweden
    Nat Methods 5:1039-45. 2008
    ..Our approach shows a path forward for systematic validation of antibodies for epitope specificity and cross-reactivity on a whole-proteome level...
  64. ncbi Phylogenetic relationships of 38 taxa of the genus Staphylococcus based on 16S rRNA gene sequence analysis
    T Takahashi
    Department of Epizootiology, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan
    Int J Syst Bacteriol 49:725-8. 1999
    The nucleotide sequences of the 16S rRNA gene (rDNA) in 38 taxa of the genus Staphylococcus were compared phylogenetically. Based on phylogenetic tree analysis, staphylococcal species were divided into 12 cluster groups...
  65. pmc Lateral transfer of genes and gene fragments in Staphylococcus extends beyond mobile elements
    Cheong Xin Chan
    ARC Centre of Excellence in Bioinformatics and Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia
    J Bacteriol 193:3964-77. 2011
    The widespread presence of antibiotic resistance and virulence among Staphylococcus isolates has been attributed in part to lateral genetic transfer (LGT), but little is known about the broader extent of LGT within this genus...
  66. pmc Practical disk diffusion method for detection of inducible clindamycin resistance in Staphylococcus aureus and coagulase-negative staphylococci
    K R Fiebelkorn
    Department of Pathology, University of Texas Health Science Center, San Antonio, Texas 78229 3750, USA
    J Clin Microbiol 41:4740-4. 2003
    ..A group of 130 clinical isolates of Staphylococcus aureus and 100 isolates of erythromycin-resistant coagulase-negative staphylococci (CNS) were examined by disk ..
  67. doi Identification of molecularly defined Staphylococcus aureus strains using matrix-assisted laser desorption/ionization time of flight mass spectrometry and the Biotyper 2.0 database
    Florian Szabados
    Institute for Hygiene and Microbiology, Department of Medical Microbiology, University of Bochum, Bochum, Germany
    J Med Microbiol 59:787-90. 2010
    ..Daltonics) has been applied for bacterial identification in a local strain collection of molecularly defined Staphylococcus aureus. We showed that the accuracy of the Biotyper 2...
  68. pmc In vitro activities of panduratin A against clinical Staphylococcus strains
    Yaya Rukayadi
    Department of Biotechnology, Yonsei University, Seoul 120 749, South Korea
    Antimicrob Agents Chemother 53:4529-32. 2009
    ..Panduratin A had a MIC at which 90% of bacteria were inhibited of 1 microg/ml for clinical staphylococcal isolates and generally was more potent than commonly used antimicrobials...
  69. ncbi Staphylococcus and biofilms
    Friedrich Götz
    Department of Microbial Genetics, Universitat Tubingen, Waldhäuser Str 70 8, D 72076 Tubingen, Germany
    Mol Microbiol 43:1367-78. 2002
    ..Concepts for the prevention of obstinate polymer-associated infections include the search for new anti-infectives active in biofilms and new biocompatible materials that complicate biofilm formation and the development of vaccines...
  70. doi Transmission of methicillin-resistant Staphylococcus pseudintermedius between infected dogs and cats and contact pets, humans and the environment in households and veterinary clinics
    E van Duijkeren
    Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, PO Box 80165, 3508 TD Utrecht, Netherlands
    Vet Microbiol 150:338-43. 2011
    The objective of this study was to investigate the prevalence of methicillin-resistant Staphylococcus pseudintermedius (MRSP) in people, pets and the environment in households with a pet with a clinical MRSP-infection within the past year...
  71. ncbi Persistent strains of coagulase-negative staphylococci in a neonatal intensive care unit: virulence factors and invasiveness
    C Klingenberg
    Department of Paediatrics, University Hospital of North Norway, Tromsø, Norway
    Clin Microbiol Infect 13:1100-11. 2007
    ..One Staphylococcus haemolyticus cluster appeared to selectively colonise and infect the most extreme pre-term infants...
  72. ncbi Staphylococcus pseudintermedius sp. nov., a coagulase-positive species from animals
    Luc A Devriese
    Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Int J Syst Evol Microbiol 55:1569-73. 2005
    ..16S rRNA gene sequence analysis revealed that its closest phylogenetic relatives are Staphylococcus intermedius and Staphylococcus delphini...
  73. pmc Complete genome sequence of Macrococcus caseolyticus strain JCSCS5402, [corrected] reflecting the ancestral genome of the human-pathogenic staphylococci
    Tadashi Baba
    Department of Microbiology and Infection Control Science, Juntendo University, 2 1 1 Hongo, Bunkyo, Tokyo 113 8421, Japan
    J Bacteriol 191:1180-90. 2009
    ..on the genome analysis of a macrococcal species that is evolutionarily closely related to the human pathogens Staphylococcus aureus and Bacillus anthracis. The essential biological pathways of M...
  74. ncbi Comparative analysis of twin-arginine (Tat)-dependent protein secretion of a heterologous model protein (GFP) in three different Gram-positive bacteria
    Daniel Meissner
    Institut für Biotechnologie 1, Forschungszentrum Julich GmbH, 52425, Julich, Germany
    Appl Microbiol Biotechnol 76:633-42. 2007
    ..potential for Tat-dependent heterologous protein secretion was compared in the three Gram-positive bacteria Staphylococcus carnosus, Bacillus subtilis, and Corynebacterium glutamicum using green fluorescent protein (GFP) as a model ..
  75. doi Linezolid-resistant clinical isolates of enterococci and Staphylococcus cohnii from a multicentre study in China: molecular epidemiology and resistance mechanisms
    Hongbin Chen
    Department of Clinical Laboratory, Peking University People s Hospital, Beijing 100044, People s Republic of China
    Int J Antimicrob Agents 42:317-21. 2013
    ..the resistance of linezolid-resistant isolates, nine Enterococcus faecalis, one Enterococcus faecium and three Staphylococcus cohnii isolates with various levels of resistance were collected from five hospitals across China in 2009-2012...
  76. doi Identification and methicillin resistance of coagulase-negative staphylococci isolated from nasal cavity of healthy horses
    Jolanta Karakulska
    Department of Immunology, Microbiology and Physiological Chemistry Faculty of Biotechnology and Animal Husbandry West Pomeranian University of Technology, Szczecin, Poland Doktora Judyma 24, 71 466, Szczecin, Poland
    J Microbiol 50:444-51. 2012
    ..felis from a horse. The species identity of the remaining Staphylococcus spp. isolates (17...
  77. pmc Multilocus sequence typing for characterization of Staphylococcus pseudintermedius
    S M Solyman
    Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, USA
    J Clin Microbiol 51:306-10. 2013
    b>Staphylococcus pseudintermedius is an opportunistic pathogen in dogs. Four housekeeping genes with allelic polymorphisms were identified and used to develop an expanded multilocus sequence typing (MLST) scheme...
  78. ncbi Development of a multiplex PCR for the identification of Staphylococcus genus and four staphylococcal species isolated from food
    S Corbiere Morot-Bizot
    Station de Recherches sur la Viande, INRA, Centre Clermont Ferrand Theix, Saint Genes Champanelle, France
    J Appl Microbiol 97:1087-94. 2004
    To develop a multiplex PCR that allows the identification of bacteria belonging to the Staphylococcus genus and in particular to the species Staphylococcus xylosus, S. saprophyticus, S. epidermidis and S...
  79. ncbi Methicillin resistance of staphylococci isolated from the skin of dogs with pyoderma
    Stephen A Kania
    Department of Comparative Medicine, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996, USA
    Am J Vet Res 65:1265-8. 2004
    ..To determine the methicillin-resistant profile of staphylococcal isolates from the skin of dogs with pyoderma...
  80. ncbi Macrolides and staphylococcal biofilms
    Jorge Parra-Ruiz
    Service of Infectious Diseases, Hospital Universitario San Cecilio, Avda Dr Olóriz 16 18012, Granada, Spain
    Rev Esp Quimioter 25:10-6. 2012
    ..Despite controversial reports, there is growing in-vitro and in-vivo evidences of anti-staphylococcal biofilm activity of macrolides that could represent a significant advance in the battle against implant-related infections...
  81. pmc Reconstruction of the phenotypes of methicillin-resistant Staphylococcus aureus by replacement of the staphylococcal cassette chromosome mec with a plasmid-borne copy of Staphylococcus sciuri pbpD gene
    Aude Antignac
    The Rockefeller University, New York, NY 10021, USA
    Antimicrob Agents Chemother 53:435-41. 2009
    The mecA gene, the central determinant of methicillin (meticillin)-resistant Staphylococcus aureus (MRSA), is not native to this bacterial species but may have originated in the animal commensal species Staphylococcus sciuri. All S...
  82. doi Methicillin-resistant Staphylococcus pseudintermedius isolated from canine pyoderma in North China
    Y Wang
    Beijing Key Laboratory of Detection Technology for Animal Derived Food Safety, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing, China
    J Appl Microbiol 112:623-30. 2012
    To determine the prevalence of carriage of methicillin-resistant Staphylococcus pseudintermedius (MRSP) among dogs with pyoderma from two small animal hospitals in North China during a 21-month period and to characterize these isolates.
  83. ncbi Coagulase negative staphylococci and their participation in pathogenesis of human infections
    A Longauerova
    Institute of Microbiology, Faculty ofMedicine, University Hospital, Comenius University, Bratislava, Slovakia
    Bratisl Lek Listy 107:448-52. 2006
    ..Lately, major interest appeared in the study of factors, mainly S. epidermidis, which participate in the biofilm formation, as well as of the determination of virulence factors of other coagulase negative staphylococci (Tab. 2, Ref. 25)...
  84. doi Linezolid-resistant clinical isolates of meticillin-resistant coagulase-negative staphylococci and Enterococcus faecium from China
    Jia Chang Cai
    2nd Affiliated Hospital of Zhejiang University, Zhejiang University, 88 Jiefang Road, Hangzhou 310009, PR China
    J Med Microbiol 61:1568-73. 2012
    Seventeen meticillin-resistant coagulase-negative staphylococci (MRCoNS), including ten Staphylococcus capitis, four Staphylococcus cohnii, two Staphylococcus haemolyticus and one Staphylococcus sciuri, and an Enterococcus faecium isolate ..
  85. doi The emerging problem of linezolid-resistant Staphylococcus
    Bing Gu
    Department of Laboratory Medicine, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    J Antimicrob Chemother 68:4-11. 2013
    ..This article systematically reviews the published literature for reports of linezolid-resistant Staphylococcus (LRS) infections to identify epidemiological, microbiological and clinical features for these infections...
  86. pmc Characterization of a mazEF toxin-antitoxin homologue from Staphylococcus equorum
    Christopher F Schuster
    Department of Microbial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen IMIT, Faculty of Science, University of Tubingen, Tubingen, Germany
    J Bacteriol 195:115-25. 2013
    ..seven putative type I and three putative type II TA systems in the genome of the nonpathogenic species strain Staphylococcus equorum SE3. Among these, a MazEF system orthologue termed MazEF(seq) was further characterized...
  87. pmc Human-to-bovine jump of Staphylococcus aureus CC8 is associated with the loss of a β-hemolysin converting prophage and the acquisition of a new staphylococcal cassette chromosome
    Grégory Resch
    Department of Fundamental Microbiology, University of Lausanne, Lausanne, Switzerland
    PLoS ONE 8:e58187. 2013
    b>Staphylococcus aureus can colonize and infect both humans and animals, but isolates from both hosts tend to belong to different lineages. Our recent finding of bovine-adapted S. aureus showing close genetic relationship to the human S...
  88. doi Serum anti-Staphylococcus pseudintermedius IgE and IgG antibodies in dogs with atopic dermatitis and nonatopic dogs
    Jennifer Bexley
    Avacta Animal Health, Unit 651, Street 5, Thorp Arch Estate, Wetherby, Leeds LS23 7FZ, UK
    Vet Dermatol 24:19-24.e5-6. 2013
    Dogs and humans with atopic dermatitis (AD) are predisposed to colonization and recurrent infection with Staphylococcus spp...
  89. doi In vitro antiseptic susceptibilities for Staphylococcus pseudintermedius isolated from canine superficial pyoderma in Japan
    Nobuo Murayama
    ASC Dermatology Service, 1 3 2 Jindaijihigashi Chofu, Tokyo 182 0012, Japan
    Vet Dermatol 24:126-9.e29. 2013
    ..therapy, particularly with chlorhexidine, is becoming increasingly common as a treatment option for canine pyoderma; however, there are limited studies on the susceptibility of Staphylococcus pseudintermedius to chlorhexidine compounds.
  90. ncbi A novel degradation pathway in the assimilation of phenanthrene by Staphylococcus sp. strain PN/Y via meta-cleavage of 2-hydroxy-1-naphthoic acid: formation of trans-2,3-dioxo-5-(2'-hydroxyphenyl)-pent-4-enoic acid
    Somnath Mallick
    Department of Microbiology, Bose Institute, Kolkata 700054, India
    Microbiology 153:2104-15. 2007
    b>Staphylococcus sp. strain PN/Y, capable of utilizing phenanthrene as a sole source of carbon and energy, was isolated from petroleum-contaminated soil...
  91. doi Comparison of antibiotic resistance, biofilm formation and conjugative transfer of Staphylococcus and Enterococcus isolates from International Space Station and Antarctic Research Station Concordia
    Katarzyna Schiwon
    Department of Environmental Microbiology Genetics, Technical University, Berlin, Germany
    Microb Ecol 65:638-51. 2013
    ..study, 29 isolates from the ISS and 55 from the Antarctic Research Station Concordia belonging to the genera Staphylococcus and Enterococcus were investigated. Resistance to one or more antibiotics was detected in 75...
  92. ncbi Methicillin-resistant strains of Staphylococcus aureus and coagulase-negative staphylococus from clinical isolates at Felege Hiwot Refferal Hospital, North West Ethiopia
    Bayeh Abera
    Bahir Dar University, Medical Faculty of Education, P O Box, 1498 Bahir Dar
    Ethiop Med J 46:149-54. 2008
    ..Methicillin-resistant staphylococci are one of the major causes of nosocomial infection. The aim of this study was to determine Methicillin-resistant strain of staphylococci and its antibiotic resistance...
  93. ncbi Staphylococcus lugdunensis infection sites: predominance of abscesses in the pelvic girdle region
    Richard Bellamy
    Department of Microbiology and Infectious Diseases, Tan Tock Seng Hospital, Singapore 308433
    Clin Infect Dis 35:E32-4. 2002
    We used a screening protocol to identify Staphylococcus lugdunensis in clinical specimens with pure or predominant growth of coagulase-negative staphylococci. S...
  94. pmc Antimicrobial susceptibility of Staphylococcus aureus and Staphylococcus pseudintermedius isolated from various animals
    Joseph E Rubin
    Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Can Vet J 52:153-7. 2011
    This study characterized the antimicrobial susceptibility of 221 Staphylococcus aureus isolated from various species, and 60 canine Staphylococcus pseudintermedius isolated from 1986 through 2000 at the Western College of Veterinary ..
  95. ncbi Mucosa or skin as source of coagulase-negative staphylococcal bacteraemia?
    Silvia F Costa
    Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock 72205, USA
    Lancet Infect Dis 4:278-86. 2004
    ....
  96. ncbi Occurrence, species distribution, antimicrobial resistance and clonality of methicillin- and erythromycin-resistant staphylococci in the nasal cavity of domestic animals
    Funda A Bagcigil
    Department of Microbiology, Istanbul University, 34320 Avcilar, Turkey
    Vet Microbiol 121:307-15. 2007
    ..Based on the analysis of data on antimicrobial consumption, the occurrence of MRCoNS in companion animals and that of ERSA in pigs reflected national and local patterns of antimicrobial usage...
  97. ncbi Phenotypic and genotypic characteristics of methicillin/oxacillin-resistant Staphylococcus intermedius isolated from clinical specimens during routine veterinary microbiological examinations
    I E M El Zubeir
    Department of Dairy Production, Faculty of Animal Production, University of Khartoum, Khartoum North 13314, Sudan
    Vet Microbiol 121:170-6. 2007
    ....
  98. doi Antimicrobial resistance of Staphylococcus pseudintermedius isolates from healthy dogs and dogs affected with pyoderma in Japan
    Kenta Onuma
    Laboratory of Veterinary Microbiology, Faculty of Veterinary Medicine, Kitasato University, Aomori 034 8628, Japan
    Vet Dermatol 23:17-22, e5. 2012
    b>Staphylococcus pseudintermedius strains were isolated from healthy dogs and dogs with pyoderma in 2000-2002 and 2009...
  99. ncbi Pathogenesis of infections due to coagulase-negative staphylococci
    Christof von Eiff
    Institute of Medical Microbiology, University of Münster Hospital and Clinics, Munster, Germany
    Lancet Infect Dis 2:677-85. 2002
    ..of the pathogenesis of infections due to CoNS and particularly focuses on virulence factors of the species Staphylococcus epidermidis...
  100. doi Sepsis due to linezolid resistant Staphylococcus cohnii and Staphylococcus kloosii: first reports of linezolid resistance in coagulase negative staphylococci from India
    M A Peer
    Department of Clinical Microbiology, Sher I Kashmir Institute of Medical Sciences, Soura, Srinagar, Kashmir, India
    Indian J Med Microbiol 29:60-2. 2011
    ..was an 18-year-old burn patient, who, after a major graft surgery, landed in sepsis, and linezolid resistant Staphylococcus cohnii with an minimum inhibitory concentration (MIC) of >256 μg/ml by both broth microdilution and Etest, ..
  101. ncbi Antibiotic resistance profiles of Staphylococcus pseudintermedius isolates from canine patients in Korea
    Jang Won Yoon
    Department of Microbiology and Research Institute for Translational System Biomics, Chung Ang University College of Medicine, Seoul 156 756, Republic of Korea
    J Microbiol Biotechnol 20:1764-8. 2010
    In this study, the prevalence of antibiotic resistance was examined among 74 Staphylococcus pseudintermedius strains recently isolated from clinical cases of canine pyoderma and otitis externa at the veterinary teaching hospital at Konkuk ..

Research Grants79

  1. Sutureless Laparoscopic Partial Nephrectomy Using Laser Tissue Welding: Preclinic
    Yasmin Wadia; Fiscal Year: 2013
    ..environment : Sterilizes contaminated wounds of drug- resistant super bugs like Methicillin-Resistant Staphylococcus aureus (MRSA), Streptococcus pyogenes and Pseudomonas aeruginosa...
  2. Human neutrophils, phospholipase A2 and S.aureus: microbial targets and responses
    William M Nauseef; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Serious infection with Staphylococcus aureus (SA) remains an important clinical challenge despite potent antibiotics...
  3. Novel Bioconjugate Vaccines to Prevent Staphylococcus aureus Infection
    JEAN CLAIRE LEE; Fiscal Year: 2013
    ..vaccine to prevent invasive, life- threatening infections by the medically important bacterial pathogen Staphylococcus aureus. Because S...
  4. Non-invasive zoonotic pathogen exposure and outcome biomarkers with follow-up in
    Christopher D Heaney; Fiscal Year: 2013
    ..training in multi-locus sequence typing (MLST) and whole genome SNP analysis (WGSA) of multidrug-resistant Staphylococcus aureus (MDRSA) isolated from nasal swabs of livestock workers and household members in an ongoing cross-..
  5. The Electricidal Effect, a Novel Anti-Biofilm Strategy
    Robin Patel; Fiscal Year: 2013
    ..that electrical currents of 20 to 2000 <A substantially reduced established Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis biofilms, a phenomenon we termed the "electricidal effect" (Antimicrob ..
  6. Investigation of Occupational Exposure to and Infection by MRSA in Rural Iowa
    Tara Smith; Fiscal Year: 2012
    ..Research Plan A recent report has documented the clinical impact of methicillin-resistant Staphylococcus aureus (MRSA), suggesting that MRSA caused over 94,000 invasive infections and more than 18,000 deaths in the ..
  7. Advanced Nitric Oxide Release Bactericidal Urinary Catheters
    Mark E Meyerhoff; Fiscal Year: 2013
    ..to understand thresholds for effective biofilm prevention (Proteus mirabilis, Enterococcus faecalis, and Staphylococcus epidermidis);(2) to understand the light emission requirements at 590nm to photochemically prevent biofilm ..
  8. Robust Peptide-Based Diagnostics of Botulinum Toxins
    John E Mueller; Fiscal Year: 2012
    ..affinity reagents to multiple other proteinaceous biothreat agents, including shiga and shiga-like toxins, Staphylococcus and Clostridium enterotoxins, abrin, and ricin...
  9. Epidemiology and Etiology of Hospitalized Pneumonia in Children
    Krow Ampofo; Fiscal Year: 2010
    ..of non-vaccine serotypes of Streptococcus pneumioniae and highly virulent clones of methcillin resistant Staphylococcus aureus (MRSA)...
  10. Therapeutics for Drug-Resistant Bacteria: Myxopyronins
    Richard H Ebright; Fiscal Year: 2013
    ..Myx exhibits potent antibacterial activity against Mycobacterium tuberculosis, Staphylococcus aureus, Streptococcus pneumoniae, Enterococcus faecalis, Enterobacter cloacae, and Clostridium difficile in ..
  11. Optimization of Neoglycoside Antibiotics for Nosocomial Pathogens and Select Agen
    Arnold Louie; Fiscal Year: 2013
    ..against a wide variety of multi-resistant Gram-negative bacilli and also against Methicillin-Resistant Staphylococcus aureus (MRSA)...
  12. Ibis T-6,000 Biosensor System
    CYNTHIA SEARS; Fiscal Year: 2010
    ..and transplant recipients with rejection and idiopathic lung diseases;2) detection of specific pathogens (Staphylococcus aureus, nosocomial multidrug resistant gram negative rods, influenza virus), their virulence determinants and ..
  13. Vaccine Assembly from Surface Proteins of Staphylococcus Aureus
    Olaf Schneewind; Fiscal Year: 2013
    A CDC/APIC sponsored study revealed in June 2007 a pressing health crisis for the United States: Staphylococcus aureus is the leading cause of bloodstream, lower respiratory tract, skin and soft tissue infections...
  14. Biofilm Infections in Postsurgical, Trauma, and Critically Ill Patients
    Carol L Wells; Fiscal Year: 2013
    ..focuses on two of the most prevalent etiologic agents of catheter-related and surgical site infections, namely Staphylococcus aureus and Enterococcus faecalis...
  15. Inhibitors of S. aureus bNOS for adjunctive therapy
    Donald T Moir; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Staphylococcus aureus is a major cause of community and hospital-acquired infections of the skin, soft tissue, and bloodstream...
  16. ENZYMOLOGY OF ANTIBIOTIC RESISTANCE
    Richard Armstrong; Fiscal Year: 2009
    ..are extant in several select human pathogens, for example, (FosA) in Pseudomonas aeruginosa, (FosB) in Staphylococcus aureus and Bacillus anthracis, and (FosX) in Brucella melitensis, Listeria monocytogenes and Clostridium ..
  17. International Symposium on Proline Metabolism and Human Health
    Donald F Becker; Fiscal Year: 2010
    ..g., Trypanosoma brucei, African sleeping sickness) and pathogenic bacteria (e.g., Staphylococcus aureus) adapt and survive, mitochondrial energetic processes, connective tissue and skin disorders, and ..
  18. Carbohydrate-based Antiinfective Agents
    Chi Huey Wong; Fiscal Year: 2013
    ..TGase for long-awaited antibiotic development against dangerous gram-positive strains of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE)...
  19. MNEI/SerpinB1: A modulator of innate pulmonary defense
    EILEEN REMOLD-O'DONNELL; Fiscal Year: 2010
    ..aeruginosa, Haemophilus influenzae) and Gram-positive (Staphylococcus aureus) organisms and in two genetic backgrounds (C57BL/6 and129S6)...
  20. Structural mechanism of DNA segregation by the pSK41 par system
    Maria Schumacher; Fiscal Year: 2010
    ..This proposal focuses on one such par system from Staphylococcus aureus multi-drug resistance plasmid pSK41...
  21. Development of a Novel PolC Inhibitor as a Gram-Positive Antibiotic
    THALE CROSS JARVIS; Fiscal Year: 2013
    ..These agents exhibit broad-spectrum activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP), Streptococcus pyogenes (Group A strep), ..
  22. Transcriptional Control by the Global Regulator Spx
    PETER A ZUBER; Fiscal Year: 2013
    ..regulator that we discovered in the spore-forming bacterium, Bacillus subtilis, but is also found in Staphylococcus aureus, Streptococcus pneumoniae, Listeria monocytogenes, and Bacillus anthracis...
  23. A common denominator of pathogenesis;a rare opportunity for novel therapeutic de
    DOUGLAS ALAN MITCHELL; Fiscal Year: 2011
    ..has uncovered SLS-like toxins are synthesized by at least three other notorious human pathogens, including Staphylococcus aureus, Listeria monocytogenes, and Clostridium botulinum...
  24. High-throughput Screenings to Identify Host Receptors for Staphylococcal Adhesins
    Renata Pasqualini; Fiscal Year: 2012
    ..Although Staphylococcus aureus is by far the most virulent of species, Staphylococcus epidermidis and Staphylococcus lugdunensis have ..
  25. Cellular functions of the essential PcrA helicase in Staphylococcus aureus
    Saleem A Khan; Fiscal Year: 2013
    ..A) is an essential protein present in Gram-positive bacteria, including important human pathogens such as Staphylococcus aureus, Streptococcus pneumonia, Clostridium perfringens, Listeria monocytogenes, Bacillus anthracis, etc...
  26. Lactoferrin for Immunomodulation of Systemic Inflammatory Response Syndrome
    Marian L Kruzel; Fiscal Year: 2011
    ..systemic events associated with lactoferrin mediation will also be investigated using methicillin-resistant Staphylococcus aureus bacteria (MRSA) infection, which is troublesome in hospital-associated (nosocomial) infections...
  27. Contribution of the Streptococcus mutans cid and lrg Murein Hydrolase Regulator H
    KELLY CHRISTINE RICE; Fiscal Year: 2010
    ..have been shown to be important regulators of cell death, autolysis and biofilm development in the pathogen Staphylococcus aureus...
  28. Prevention and therapy of Staphylococcus aureus infections
    Olaf Schneewind; Fiscal Year: 2010
    ..b>Staphylococcus aureus is the leading cause of bloodstream, lower respiratory tract, skin and soft tissue infections in the ..
  29. Defining evolutionary trajectories: Molecular adaptation to antibiotic resistance
    ADIL YOUSIF SHAMOO; Fiscal Year: 2012
    ..Data from 2004 show that despite the best efforts of the medical community, methicillin resisistant Staphylococcus aureus (MRSA) were found in over 60% and vancomycin resistant Enterococci (VRE) in nearly 30% of ICU patients ..
  30. Rapid, Highly Multiplexed and Sensitive Blood Test for Drug-resistant Bacteria
    ARMIN H REITMAIR; Fiscal Year: 2010
    ..Specific aims are: 1. Separate detection and quantification of eight genetic markers (species-specific for Staphylococcus aureus, S. epidermidis, Enterococcus faecalis, E...
  31. National surveillance of emerging MDR in pediatric Enterobacteriaceae infections
    Danielle M Zerr; Fiscal Year: 2013
    ..at understanding the epidemiology of resistance in Gram-positive organisms, especially methicillin-resistant Staphylococcus aureus, much less is known about the epidemiology of multi-drug resistance in Gram-negative organisms, ..
  32. Novel biofilm polymicrobial infection-resistant implants for otologic application
    Paul Stoodley; Fiscal Year: 2010
    ..in Phase I that we can suppress biofilm formation and planktonic growth of Pseudomonas aeruginosa and Staphylococcus aureus for an extended period of time...
  33. Structures of RNA processing and Silencing Enzymes in Prokaryotes
    Hong Li; Fiscal Year: 2013
    ..tuberculosis, Haemophilus influenzae, Helicobacter pylori, Neisseria meningitides, Vibrio vulnificus, Staphylococcus aureus, Salmonella Typhi and Clostridium tetani...
  34. Regulation of NETosis in antibacterial lung defense
    EILEEN REMOLD-O'DONNELL; Fiscal Year: 2013
    ..Pneumonias resulting from failure to eradicate bacterial (Streptococcus pneumonia, Haemophilus influenza, Staphylococcus aureus, Pseudomonas aeruginosa) and viral (rhinovirus, influenza virus) infections are responsible for a ..
  35. Biofilm matrix-degrading enzymes for the treatment and prevention of S. aureus-as
    Jeffrey B Kaplan; Fiscal Year: 2013
    ..All experiments will be carried out using the common wound pathogen Staphylococcus aureus. Topical biocides will include povidone iodine and chlorhexidine gluconate...
  36. Exploiting deep ocean biology for biomedical discovery
    David C Rowley; Fiscal Year: 2011
    ..of this testing (AIM 3) will be growth inhibition of both ATCC and clinical strains of multiple drug resistant Staphylococcus aureus, Acinetobacter baumannii, Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae...
  37. Structure and Mechanism of SAM-responsive Riboswitches
    Robert T Batey; Fiscal Year: 2013
    ..are under riboswitch control in a number of medically important pathogens including Listeria monocytogenes, Staphylococcus aureus, Pseudomonas aeruginosa, and Mycobacterium tuberculosis making them of great interest as novel targets ..
  38. Using PET isotopes to identify drug targets and to diagnose infectious diseases
    Peter J Tonge; Fiscal Year: 2010
    ..The initial focus will be on pathogens such as Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus, however the approach has general applicability...
  39. Role of Staphylococcus aureus alpha-hemolysin in disease
    Juliane Bubeck Wardenburg; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Role of Staphylococcus aureus alpha-hemolysin in disease Staphylococcus aureus is the leading cause of bloodstream, lower respiratory tract, skin and soft tissue infections in the United States...
  40. HLA class II transgenic mouse models for S. aureus infections and superantigens
    Govindarajan Rajagopalan; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Staphylococcus aureus is a ubiquitous Gram-positive organism implicated in a spectrum of diseases;from benign, localized skin infections to life-threatening, systemic illnesses including pneumonia, ..
  41. Host defense against Staphylococcus aureus skin infections
    Lloyd S Miller; Fiscal Year: 2010
    ..is to gain insight into mechanisms of cutaneous host defense against the common bacterial skin pathogen Staphylococcus aureus. S...
  42. Development of Inhaled Vancomycin for Treatment of MRSA Infections in CF
    Taneli Jouhikainen; Fiscal Year: 2012
    ..developing a novel inhaled dry-powder form of vancomycin (AEROVANC) for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infection, initially in cystic fibrosis (CF) patients and subsequently in other high risk ..
  43. Boosting Innate Immunity Through HIF to Treat Antibiotic-Resistant Infections
    ROBERT ALAN SHALWITZ; Fiscal Year: 2013
    ..boost HIF-1 in human phagocytes and cause them to kill pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) with efficiency comparable to classical antibiotic therapy...
  44. Pathogensis of Bacterial corneal infection
    Gerald B Pier; Fiscal Year: 2013
    ..Specifically, this application will focus on infections caused by Pseudomonas aeruginosa and Staphylococcus aureus. These two pathogens are among the most common causes of serious corneal infections...
  45. Biomarker Screening of Essential Putative Glycoprotease Inhibitor
    Yinduo Ji; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Given the well-known pathogenicity of Staphylococcus aureus, the emergence of methicillin-resistant S. aureus (MRSA) and vancomycin-resistant S...
  46. Proteomics of RNA polymerase interactomes in pathogenic bacteria
    Evgeny Nudler; Fiscal Year: 2013
    ..the transient interactions of the central enzyme of gene expression, RNA polymerase, in pathogenic bacteria Staphylococcus aureus and Bacillus anthracis, as well as the topology and composition of the more stable macromolecular ..
  47. Chemistry, Structure and Biology of Thiol Transferases
    Richard N Armstrong; Fiscal Year: 2013
    ..expressed and purified the FosB enzymes from several sources including Bacillus cereus, Bacillus anthracis and Staphylococcus aureus which puts us in an excellent position to accomplish this aim...
  48. Research and Development of a Novel System to Produce Polysaccharide Conjugate Va
    Peng George Wang; Fiscal Year: 2013
    ..The first includes E. coli O157, O104 and Shigella sonnei;the second includes Staphylococcus aureus...
  49. Mechanisms and regulation of serine resolvases
    Phoebe A Rice; Fiscal Year: 2012
    ..reaction that is important for stable maintenance of many drug resistance-carrying plasmids found in Staphylococcus aureus, a common cause of opportunistic infections...
  50. Inhibition of lung defense by air pollutant particulates
    LISA KATHLEEN RYAN; Fiscal Year: 2010
    ..vanadium and then infected with airway pathogens that cause pneumonia, such as Streptococcus zooepidemicus and Staphylococcus aureus...
  51. Innovative technologies to effectively treat Multi-drug resistant and/or biofilm-
    Jie Wen; Fiscal Year: 2010
    ..resistant bacteria (MDR) such as Acinetobacter baumannii, Klebsiella pneumoniae, methicillin-resistant Staphylococcus aureus, and multi-drug resistant Pseudomonas aeruginosa...
  52. Superantigen-Induced Vascular Injury and DIC
    JACK J HAWIGER; Fiscal Year: 2011
    ..Community- acquired Methicillin-Resistant Staphylococcus aureus (CA-MRSA) is responsible for Acute Lung Injury (ALI) associated with necrotizing pneumonia often ..
  53. Protein Structure/Function by NMR, Crystallography and Computational Chemistry
    Eric Oldfield; Fiscal Year: 2012
    ..is to develop molecules that inhibit formation of the orange carotenoid virulence factor, staphyloxanthin, in Staphylococcus aureus...
  54. The Abeta protein of Alzheimer's Disease is an antimicrobial peptide
    Robert D Moir; Fiscal Year: 2013
    ..the growth of eight clinically important microorganisms, including Candida albicans, Escherichia coli, Staphylococcus epidermidis, Streptococcus pneumoniae, Staphylococcus aureus, Listeria monocytogenes, Enterococcus faecalis, ..
  55. Mitochondrial DNA Repair and Biogenesis
    Raquel R Bartz; Fiscal Year: 2013
    ..OGG1 and nuclear coactivators, PGC-11 and its family members, in mtDNA maintenance and biogenesis in a murine Staphylococcus sepsis model...
  56. REGULATION OF LIPID METABOLISM IN BACTERIA
    Charles O Rock; Fiscal Year: 2013
    ..the research plan on investigating fatty acid and phospholipid synthesis in two important human pathogens: Staphylococcus aureus and Streptococcus pneumoniae...
  57. Synergy between TLR2 and IL-22R in airway epithelial cells during MRSA challenge
    Jeremy P McAleer; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The gram-positive organism Staphylococcus aureus colonizes the nasal passages in 20-50 percent of people, and community-acquired pneumonia caused by methicillin-resistant S. aureus (MRSA) is increasing...
  58. Anti-Autolysin Passive Immunity for MRSA Osteomyelitis
    JOHN LINFORTH DAISS; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Recently methicillin resistant Staphylococcus aureus (MRSA) has surpased HIV as the most deadly pathogen in the United States, accounting for over 100,000 deaths per year...
  59. Antimicrobial Phototherapy of Antibiotic Resistant Chronic Sinusitis
    MERRILL ABRAHAM BIEL; Fiscal Year: 2011
    ..presence of antibiotic resistant Pseudomonas aerugenosa, Hemophilus influenza, Streptococcus pneumoniae and Staphylococcus aureus biofilms in the sinuses of cure resistant CRS...
  60. Barcoded Magnetic Beads for Rapid Tests of MRSA and Respiratory Viral Panels
    WINSTON Z HO; Fiscal Year: 2010
    ..The human and financial impact of Methicillin-resistant Staphylococcus aureus (MRSA) is high. MRSA now accounts for greater than 60% of hospital-acquired S...
  61. Impact of the Nasal Microbiome on S. aureus Colonization and Infection
    Mary Bessesen; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Staphylococcus aureus infections of the bloodstream, lung, surgical sites, and skin and soft tissues are a leading cause of morbidity and mortality...
  62. Multi-specific Antibody Therapy by targeting S. aureus toxins and polysaccharides
    M Javad Aman; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Staphylococcus aureus is a human pathogen that causes a wide range of diseases from skin and soft tissue infections (SSTI) to life threatening sepsis and pneumonia. Infections with S...
  63. S. aureus and Regulatory T cells in the Failure of Oral Tolerance
    Anne Marie Singh; Fiscal Year: 2013
    ..Exciting new preliminary data demonstrate increased Staphylococcus aureus burden in the gut of patients with food allergy, and previous work has also illustrated increased IL-10 ..
  64. HTS assay and configuration for inhibitors of the UDP-Mur formation pathway
    Michael McNeil; Fiscal Year: 2009
    ..In addition, new inhibitors of PG synthesis are needed for eubacteria in general, such a methicillin resistant Staphylococcus aureus and bioterrorist agents including Burkholderia pseudomallei and Yersinia pestis...
  65. Selenium Coated Dialysis Catheters for Reduced Biofilm Formation
    Eric Tobin; Fiscal Year: 2009
    ..Phase I successfully demonstrated significant (>90%) reduction in biofilm formation for both gram positive (Staphylococcus aureus) and gram negative (Pseudomonas aeruginosa) bacteria on selenium coated polyurethane catheter material...
  66. Defining the bacterial factors that modulate sensitivity to B-lactam in CA-MRSA
    AMBROSE LIN YAU CHEUNG; Fiscal Year: 2010
    ..provided by applicant): Recent cases of infections caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) strains in healthy individuals have raised concerns worldwide...
  67. Enhancement of antimicrobics by electrical current
    Robin Patel; Fiscal Year: 2007
    ..non-quinolone, non-tetracycline antimicrobics and whether the bioelectric effect is generalizable to Staphylococcus aureus...
  68. Host Response in S. aureus Infections: Role of T cells
    Arthur Tzianabos; Fiscal Year: 2006
    unreadable] DESCRIPTION (provided by applicant): Staphylococcus aureus is an opportunistic bacterial pathogen responsible for a diverse spectrum of human and animal diseases, including wound infections, osteomyelitis, endocarditis, and ..
  69. ELECTRON TRANSPORT VARIANTS IN STAPHYLOCOCCAL DISEASE
    Richard Proctor; Fiscal Year: 2001
    DESCRIPTION (Adapted from the applicant's abstract): Staphylococcus aureus causes persistent and recurrent infections, even when highly active antibiotics are used. Dr...
  70. STAPHYLOCOCCUS AUREUS: CAPSULAR ANTIGENS AND IMMUNITY
    Jean Lee; Fiscal Year: 1993
    b>Staphylococcus aureus is a bacterial pathogen responsible for a diverse spectrum of human and animal diseases. Most S. aureus isolates are microencapsulated, i.e...
  71. Structure and Cell-Wall Targeting of the Staphylolytic Enzyme Lysostaphin
    KEITH GRISCOM INMAN; Fiscal Year: 2010
    A major impediment to successful treatment of Staphylococcus aureus is its tendency to develop antibiotic resistance...
  72. METHICILLIN RESISTANCE OF STAPHYLOCOCCUS AUREUS
    Henry Chambers; Fiscal Year: 1993
    ..research is to identify the components and their interrelationships controlling methicillin resistance in Staphylococcus aureus...
  73. Scaffolds for Synthesis of Probes Directed Against Class II HMG-CoA Reductases
    Cynthia Stauffacher; Fiscal Year: 2007
    ..shown that a number of common human pathogens, including Enterococcus faecalis, Streptococcus pneumoniae and Staphylococcus aureus are dependent on enzymes in the mevalonate pathway for biosynthesis of IPP, including the central ..
  74. Novel antibacterials targeting the 50S ribosomal subunit
    Joyce Sutcliffe; Fiscal Year: 2005
    ..For use in nosocomial infections caused by Gram-positive pathogens, a drug must cover Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, and Enterococcus faecium...
  75. Mechanisms of Sequence-Based Resistance to Viruses and Plasmids in Eubacteria
    Erik J Sontheimer; Fiscal Year: 2010
    ..Genome database searches have revealed the presence of a relatively simple CRISPR/cas locus in a strain of Staphylococcus epidermidis, and the sequence of the locus suggests that it specifies resistance not only to bacteriophages ..
  76. Statewide Implementation of Guidelines to Control MRSA
    Loreen Herwaldt; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Methicillin (oxacillin)-resistant Staphylococcus aureus (MRSA) is by far the most common resistant bacterial pathogen...
  77. REGULATION OF BETA-LACTAMASE IN STAPHYLOCOCCUS AUREUS
    Corinne Hackbarth; Fiscal Year: 2000
    ..protein 2a (PBP2a), which are responsible for resistance to the beta-lactam class of antibiotics in Staphylococcus aureus. S...
  78. Genetic Basis of Virulence of Community MRSA Clone USA300
    Henry F Chambers; Fiscal Year: 2010
    b>Staphylococcus aureus is a major human pathogen. It can cause rapidly fatal infections. A highly virulent clone of methicillin resistant S. aureus (MRSA), USA300, is epidemic in communities in the United States...
  79. SITE SPECIFIC RECOMBINATION IN STAPHYLOCOCCUS AUREUS
    Ellen Murphy; Fiscal Year: 1990
    Tn554 is a transposable element in Staphylococcus aureus that encodes resistances to spectinomycin and to the macrolide-lincosamide-streptogramin B antibiotics. Tn554 inserts efficiently into a unique site in the S. aureus chromosome...