haemophilus

Summary

Summary: A genus of PASTEURELLACEAE that consists of several species occurring in animals and humans. Its organisms are described as gram-negative, facultatively anaerobic, coccobacillus or rod-shaped, and nonmotile.

Top Publications

  1. ncbi Haemophilus haemolyticus: a human respiratory tract commensal to be distinguished from Haemophilus influenzae
    Timothy F Murphy
    Department of Medicine, University at Buffalo, State University of New York, Buffalo, NY, USA
    J Infect Dis 195:81-9. 2007
  2. pmc Bacterial infection in chronic obstructive pulmonary disease in 2000: a state-of-the-art review
    S Sethi
    Division of Pulmonary and Critical Medicine, State University of New York at Buffalo, Buffalo, New York, USA
    Clin Microbiol Rev 14:336-63. 2001
  3. pmc Pharyngeal colonization dynamics of Haemophilus influenzae and Haemophilus haemolyticus in healthy adult carriers
    Deepa Mukundan
    Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109 0244, USA
    J Clin Microbiol 45:3207-17. 2007
  4. pmc Adhesive activity of the haemophilus cryptic genospecies cha autotransporter is modulated by variation in tandem Peptide repeats
    Amanda J Sheets
    Department of Pediatrics, Duke University Medical Center, Children s Health Center, Durham, NC 27710, USA
    J Bacteriol 193:329-39. 2011
  5. pmc Haemophilus haemolyticus isolates causing clinical disease
    Raydel Anderson
    Meningitis and Vaccine Preventable Disease Branch, Division of Bacterial Diseases, National Center for Infectious and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Clin Microbiol 50:2462-5. 2012
  6. ncbi Macrolide resistance of Staphylococcus aureus and Haemophilus species associated with long-term azithromycin use in cystic fibrosis
    Sonja J Phaff
    Department of Pediatric Pulmonology and Allergology, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
    J Antimicrob Chemother 57:741-6. 2006
  7. pmc Detection of cryptic genospecies misidentified as Haemophilus influenzae in routine clinical samples by assessment of marker genes fucK, hap, and sodC
    Niels Nørskov-Lauritsen
    Department of Clinical Microbiology, Aarhus University Hospital Skejby, Denmark
    J Clin Microbiol 47:2590-2. 2009
  8. pmc Relationships of nontypeable Haemophilus influenzae strains to hemolytic and nonhemolytic Haemophilus haemolyticus strains
    Kirk W McCrea
    Department of Epidemiology, University of Michigan School of Public Health Tower, 109 Observatory, Ann Arbor, MI 48109 2029, USA
    J Clin Microbiol 46:406-16. 2008
  9. pmc Nasopharyngeal carriage of Haemophilus haemolyticus in otitis-prone and healthy children
    Lea Ann S Kirkham
    School of Paediatrics and Child Health, The University of Western Australia, Subiaco, Western Australia, Australia
    J Clin Microbiol 48:2557-9. 2010
  10. ncbi Haemophilus influenzae and Haemophilus haemolyticus in tonsillar cultures of adults with acute pharyngotonsillitis
    Muneki Hotomi
    Department of Otolaryngology Head and Neck Surgery, Wakayama Medical University, 811 1 Kimiidera, Wakayama Shi, Wakayama, 640 8501, Japan
    Auris Nasus Larynx 37:594-600. 2010

Detail Information

Publications191 found, 100 shown here

  1. ncbi Haemophilus haemolyticus: a human respiratory tract commensal to be distinguished from Haemophilus influenzae
    Timothy F Murphy
    Department of Medicine, University at Buffalo, State University of New York, Buffalo, NY, USA
    J Infect Dis 195:81-9. 2007
    b>Haemophilus influenzae is a common pathogen in adults with chronic obstructive pulmonary disease (COPD). In a prospective study, selected isolates of apparent H. influenzae had an altered phenotype...
  2. pmc Bacterial infection in chronic obstructive pulmonary disease in 2000: a state-of-the-art review
    S Sethi
    Division of Pulmonary and Critical Medicine, State University of New York at Buffalo, Buffalo, New York, USA
    Clin Microbiol Rev 14:336-63. 2001
    ..Nontypeable Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae are the most common causes of exacerbations, ..
  3. pmc Pharyngeal colonization dynamics of Haemophilus influenzae and Haemophilus haemolyticus in healthy adult carriers
    Deepa Mukundan
    Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109 0244, USA
    J Clin Microbiol 45:3207-17. 2007
    b>Haemophilus influenzae is an important cause of respiratory infections, including acute otitis media, sinusitis, and chronic bronchitis, which are preceded by asymptomatic H. influenzae colonization of the human pharynx...
  4. pmc Adhesive activity of the haemophilus cryptic genospecies cha autotransporter is modulated by variation in tandem Peptide repeats
    Amanda J Sheets
    Department of Pediatrics, Duke University Medical Center, Children s Health Center, Durham, NC 27710, USA
    J Bacteriol 193:329-39. 2011
    The Haemophilus cryptic genospecies is an important cause of maternal genital tract and neonatal systemic infections and initiates infection by colonizing the genital or respiratory epithelium...
  5. pmc Haemophilus haemolyticus isolates causing clinical disease
    Raydel Anderson
    Meningitis and Vaccine Preventable Disease Branch, Division of Bacterial Diseases, National Center for Infectious and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Clin Microbiol 50:2462-5. 2012
    We report seven cases of Haemophilus haemolyticus invasive disease detected in the United States, which were previously misidentified as nontypeable Haemophilus influenzae. All cases had different symptoms and presentations...
  6. ncbi Macrolide resistance of Staphylococcus aureus and Haemophilus species associated with long-term azithromycin use in cystic fibrosis
    Sonja J Phaff
    Department of Pediatric Pulmonology and Allergology, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
    J Antimicrob Chemother 57:741-6. 2006
    ..The purpose of this study was to determine the association between long-term use of azithromycin in CF patients and change over time in macrolide susceptibility of Staphylococcus aureus and Haemophilus spp.
  7. pmc Detection of cryptic genospecies misidentified as Haemophilus influenzae in routine clinical samples by assessment of marker genes fucK, hap, and sodC
    Niels Nørskov-Lauritsen
    Department of Clinical Microbiology, Aarhus University Hospital Skejby, Denmark
    J Clin Microbiol 47:2590-2. 2009
    Clinical isolates of Haemophilus influenzae were assessed for the presence of fucK, hap, and sodC by hybridization with gene-specific probes, and isolates diverging from the expected H...
  8. pmc Relationships of nontypeable Haemophilus influenzae strains to hemolytic and nonhemolytic Haemophilus haemolyticus strains
    Kirk W McCrea
    Department of Epidemiology, University of Michigan School of Public Health Tower, 109 Observatory, Ann Arbor, MI 48109 2029, USA
    J Clin Microbiol 46:406-16. 2008
    b>Haemophilus influenzae is both a human respiratory pathogen and pharyngeal commensal, while H. haemolyticus, the closest phylogenetic relative of H. influenzae, is arguably a strict pharyngeal commensal...
  9. pmc Nasopharyngeal carriage of Haemophilus haemolyticus in otitis-prone and healthy children
    Lea Ann S Kirkham
    School of Paediatrics and Child Health, The University of Western Australia, Subiaco, Western Australia, Australia
    J Clin Microbiol 48:2557-9. 2010
    b>Haemophilus haemolyticus is often incorrectly categorized as nontypeable Haemophilus influenzae (NTHI) upon culture...
  10. ncbi Haemophilus influenzae and Haemophilus haemolyticus in tonsillar cultures of adults with acute pharyngotonsillitis
    Muneki Hotomi
    Department of Otolaryngology Head and Neck Surgery, Wakayama Medical University, 811 1 Kimiidera, Wakayama Shi, Wakayama, 640 8501, Japan
    Auris Nasus Larynx 37:594-600. 2010
    The aim of this study was to evaluate the clinical implication of Haemophilus haemolyticus, one of the closest relative of Haemophilus influenzae, on acute pharyngotonsillitis.
  11. ncbi Evolution of the paralogous hap and iga genes in Haemophilus influenzae: evidence for a conserved hap pseudogene associated with microcolony formation in the recently diverged Haemophilus aegyptius and H. influenzae biogroup aegyptius
    Mogens Kilian
    Department of Medical Microbiology and Immunology, University of Aarhus, DK 8000 Aarhus C, Denmark
    Mol Microbiol 46:1367-80. 2002
    Certain non-capsulate strains belonging to the Haemophilus influenzae/Haemophilus aegyptius complex show unusually high pathogenicity, but the evolutionary origin of these virulent phenotypes, termed H...
  12. pmc Identification of a novel trimeric autotransporter adhesin in the cryptic genospecies of Haemophilus
    Amanda J Sheets
    Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    J Bacteriol 190:4313-20. 2008
    b>Haemophilus biotype IV strains belonging to the recently recognized Haemophilus cryptic genospecies are an important cause of maternal genital tract and neonatal systemic infections and initiate infection by colonizing the genital or ..
  13. pmc Identification of HACEK clinical isolates by matrix-assisted laser desorption ionization-time of flight mass spectrometry
    Marc Roger Couturier
    University of Utah School of Medicine, Department of Pathology, Salt Lake City, UT 84108, USA
    J Clin Microbiol 49:1104-6. 2011
    ..We assessed this technology for the identification of 103 Haemophilus parainfluenzae, Aggregatibacter aphrophilus, Aggregatibacter actinomycetemcomitans, Cardiobacterium hominis, ..
  14. pmc Outer membrane proteins and DNA profiles in strains of Haemophilus parasuis recovered from systemic and respiratory sites
    A Ruiz
    Department of Clinical and Population Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA
    J Clin Microbiol 39:1757-62. 2001
    Polyserositis caused by Haemophilus parasuis is an important disease that affects mostly weaned pigs...
  15. ncbi The sodA gene as a target for phylogenetic dissection of the genus Haemophilus and accurate identification of human clinical isolates
    Vincent Cattoir
    Laboratoire de Bacteriologie virologie, Faculte de Medecine, Universite de Rennes 1, F 35034 Rennes, France
    Int J Med Microbiol 296:531-40. 2006
    The genus Haemophilus constitutes a heterogeneous group of Pasteurellaceae species, and conventional identification of isolates other than Haemophilus influenzae and Haemophilus parainfluenzae is often challenging...
  16. pmc Multicenter evaluation of the new Vitek 2 Neisseria-Haemophilus identification card
    Robert P Rennie
    Medical Microbiology Laboratory, University of Alberta Hospital, Edmonton, AB, Canada
    J Clin Microbiol 46:2681-5. 2008
    The new Neisseria-Haemophilus identification (NH) card for Vitek 2 was compared with 16S rRNA gene sequencing (16S) as the reference method for accurate identification of Neisseria spp., Haemophilus spp...
  17. pmc Microbiological evaluation of the new VITEK 2 Neisseria-Haemophilus identification card
    Giuseppe Valenza
    Institute of Hygiene and Microbiology, University of Wurzburg, Josef Schneider Str 2 E1, 97080, Wurzburg, Germany
    J Clin Microbiol 45:3493-7. 2007
    ..VITEK 2 is an automated identification system for diverse bacterial and fungal species. A new card (the Neisseria-Haemophilus [NH] card) for the identification of Neisseria spp., Haemophilus spp...
  18. pmc Presence of copper- and zinc-containing superoxide dismutase in commensal Haemophilus haemolyticus isolates can be used as a marker to discriminate them from nontypeable H. influenzae isolates
    W W Mary Fung
    Department of Paediatrics, Division of Medicine, Imperial College, St Mary s Campus, London W2 1PG, United Kingdom
    J Clin Microbiol 44:4222-6. 2006
    Respiratory isolates of Haemophilus haemolyticus are regularly misclassified as nontypeable (NT) Haemophilus influenzae due to an aberrant hemolytic reaction on blood agar, with implications for treatment...
  19. pmc Haemophilus influenzae outer membrane protein P6 molecular characterization may not differentiate all strains of H. Influenzae from H. haemolyticus
    Arthur Chang
    Rochester General Hospital, Rochester General Research Institute, Center for Infectious Diseases and Immunology, Rochester, NY 14621, USA
    J Clin Microbiol 48:3756-7. 2010
    Distinguishing nontypeable Haemophilus influenzae and Haemophilus haemolyticus isolates by outer membrane protein (OMP) P6 gene sequencing is complicated by sequence variants in isolates...
  20. ncbi The HaeIV restriction modification system of Haemophilus aegyptius is encoded by a single polypeptide
    A Piekarowicz
    Institute of Microbiology, University of Warsaw, Nowy Swiat 67, Warsaw, 00 046, Poland
    J Mol Biol 293:1055-65. 1999
    ..The gene encoding the HaeIV ENase was cloned from Haemophilus aegyptius into pUC19 using a previously described system that does not need the knowledge that a particular ..
  21. pmc Comparison of laboratory-based and phylogenetic methods to distinguish between Haemophilus influenzae and H. haemolyticus
    Sara A Sandstedt
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan 48109 2029, United States
    J Microbiol Methods 75:369-71. 2008
    New methods to distinguish between nontypeable Haemophilus influenzae and nonhemolytic H. haemolyticus were compared...
  22. pmc Phase variation and conservation of lipooligosaccharide epitopes in Haemophilus somnus
    T J Inzana
    Center for Molecular Medicine and Infectious Diseases, Virginia Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, USA
    Infect Immun 65:4675-81. 1997
    The bovine-specific pathogen Haemophilus somnus is capable of undergoing structural and antigenic phase variation in its lipooligosaccharide (LOS) components after in vivo and in vitro passage...
  23. ncbi Analysis of Haemophilus parasuis by multilocus enzyme electrophoresis
    P J Blackall
    Animal Research Institute, Yeerongpilly, OLD, Australia
    Vet Microbiol 56:125-34. 1997
    The diversity among 40 Australian isolates and eight reference strains of Haemophilus parasuis was examined using multilocus enzyme electrophoresis...
  24. ncbi Typing of Haemophilus parasuis strains by PCR-RFLP analysis of the tbpA gene
    V A de la Puente Redondo
    Department of Animal Health, Faculty of Veterinary Medicine, , Spain
    Vet Microbiol 92:253-62. 2003
    On the basis of a species-specific PCR assay, a RFLP analysis for typing of Haemophilus parasuis strains was developed and evaluated. Amplification was based on the gene tbpA, encoding a transferrin-binding protein...
  25. ncbi Development of a PCR test for identification of Haemophilus somnus in pure and mixed cultures
    O Angen
    Danish Veterinary Laboratory, Copenhagen, Denmark
    Vet Microbiol 63:39-48. 1998
    Based on the 16S rRNA sequences of a collection of well-characterized strains of Haemophilus somnus a set of primers was selected as candidates for a species-specific PCR test. All investigated H...
  26. pmc Value of indirect hemagglutination and coagglutination tests for serotyping Haemophilus parasuis
    M L Del Rio
    Department of Animal Health, Faculty of Veterinary Medicine, Leon, Spain
    J Clin Microbiol 41:880-2. 2003
    ..and a coagglutination test (CA) were evaluated using saline, boiled, and autoclaved extracts for serotyping Haemophilus parasuis. CA showed several cross-reactions, whereas IHA gave rise to specific reactions, with minor exceptions...
  27. ncbi Prevalence of Haemophilus parasuis serovars isolated in Spain from 1993 to 1997
    X Rúbies
    Laboratorios Hipra S A, Girona, Spain
    Vet Microbiol 66:245-8. 1999
    From 1993 to 1997, 327 strains of Haemophilus parasuis were isolated from spanish swine in our Diagnostic Laboratory and 174 strains (53.2%) were serotyped. Four serotypes, sv. 5 (18.4%), sv 4 (16%), sv. 2 (9.2%) and sv...
  28. pmc Genome sequences for five strains of the emerging pathogen Haemophilus haemolyticus
    I King Jordan
    School of Biology, Georgia Institute of Technology, Atlanta, Georgia30333, USA
    J Bacteriol 193:5879-80. 2011
    ..the first whole-genome sequences for five strains, two carried and three pathogenic, of the emerging pathogen Haemophilus haemolyticus. Preliminary analyses indicate that these genome sequences encode markers that distinguish H...
  29. ncbi Haemophilus segnis polymicrobial and monomicrobial bacteraemia identified by 16S ribosomal RNA gene sequencing
    Susanna Kar Pui Lau
    Department of Microbiology, University of Hong Kong, Queen Mary Hospital
    J Med Microbiol 51:635-40. 2002
    This paper reports a case of Haemophilus segnis polymicrobial bacteraemia and a case of H. segnis monomicrobial bacteraemia identified by 16S ribosomal RNA gene sequencing...
  30. pmc Incorporation of N-acetylneuraminic acid into Haemophilus somnus lipooligosaccharide (LOS): enhancement of resistance to serum and reduction of LOS antibody binding
    Thomas J Inzana
    Center for Molecular Medicine and Infectious Diseases, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061 0342, USA
    Infect Immun 70:4870-9. 2002
    b>Haemophilus somnus isolates from cases of thrombotic meningoencephalitis, pneumonia, and other disease sites are capable of undergoing a high rate of phase variation in the oligosaccharide component of their lipooligosaccharides (LOS)...
  31. ncbi Experimental Haemophilus somnus pneumonia in calves and immunoperoxidase localization of bacteria
    R P Gogolewski
    Vet Pathol 24:250-6. 1987
    Pneumonia was produced in nine, conventionally reared calves by intrabronchial inoculation with Haemophilus somnus. Volumes of pneumonic lung were determined stereologically, following serial slicing of lungs fixed by vascular perfusion...
  32. ncbi Molecular analysis of a gene encoding a serum-resistance-associated 76 kDa surface antigen of Haemophilus somnus
    S P Cole
    Department of Pathology, University of California San Diego Medical Center 92103 8416
    J Gen Microbiol 139:2135-43. 1993
    b>Haemophilus somnus is a Gram-negative bacterial bovine pathogen which can cause disease or be carried asymptomatically. We previously showed that four serum-sensitive isolates from asymptomatic carriers lacked a 13...
  33. ncbi Purification and renaturation of membrane neuraminidase from Haemophilus parasuis
    Carol A Lichtensteiger
    Department of Pathobiology, Veterinary Diagnostic Laboratory, University of Illinois Urbana Champaign Campus, 2001 South Lincoln Avenue, Urbana, IL 61802, USA
    Vet Microbiol 93:79-87. 2003
    b>Haemophilus parasuis, which causes polyserositis, polysynovitis, meningitis, septicemia, and pneumonia in pigs, has emerged as an increasing problem in modern swine production systems. Co-factors for and the pathogenesis of H...
  34. ncbi Clinical characteristics of invasive Haemophilus aphrophilus infections
    Shao Tsung Huang
    Division of Infectious Diseases, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
    J Microbiol Immunol Infect 38:271-6. 2005
    b>Haemophilus aphrophilus, an oral fastidious Gram-negative commensal with low pathogenicity, is a member of the HACEK group (H. aphrophilus, H...
  35. pmc Utility of extended blood culture incubation for isolation of Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, and Kingella organisms: a retrospective multicenter evaluation
    Cathy A Petti
    Department of Medicine, University of Utah School of Medicine, Salt Lake City, USA
    J Clin Microbiol 44:257-9. 2006
    The incidence of and average time to detection for Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, and Kingella (HACEK) bacteria in blood cultures with standard incubation and the utility of extended incubation of blood culture ..
  36. ncbi Characterization of the diversity of Haemophilus parasuis field isolates by use of serotyping and genotyping
    Simone Oliveira
    Department of Clinical and Population Sciences, University of Minnesota, Saint Paul, MN 55108, USA
    Am J Vet Res 64:435-42. 2003
    To characterize the genetic diversity of Haemophilus parasuis field isolates with regard to serovar, herd of origin, and site of isolation.
  37. ncbi Proposal of Histophilus somni gen. nov., sp. nov. for the three species incertae sedis 'Haemophilus somnus', 'Haemophilus agni' and 'Histophilus ovis'
    Øystein Angen
    Danish Veterinary Institute, Bulowsvej 27, DK 1790 Copenhagen V, Denmark
    Int J Syst Evol Microbiol 53:1449-56. 2003
    Earlier investigations have shown that 'Haemophilus somnus', 'Haemophilus agni' and 'Histophilus ovis' represent the same species...
  38. pmc Poor clinical outcome for meningitis caused by Haemophilus influenzae serotype A strains containing the IS1016-bexA deletion
    Josilene B T Lima
    Gonçalo Moniz Research Center, Oswaldo Cruz Foundation, Brazilian Ministry of Health, Salvador, Brazil
    J Infect Dis 202:1577-84. 2010
    Since the introduction of Haemophilus influenzae type b (Hib) conjugate vaccines, meningitis caused by serotypes other than Hib has gained in importance...
  39. ncbi Structural analysis of the phase-variable lipooligosaccharide from Haemophilus somnus strain 738
    A D Cox
    Institute for Biological Sciences, National Research Council, Ottawa, ON, Canada
    Eur J Biochem 253:507-16. 1998
    The structure of the phase variable lipooligosaccharide (LOS) from Haemophilus somnus strain 738 was elucidated. The LOS was subjected to a variety of degradative procedures...
  40. pmc Prevalence of the sodC gene in nontypeable Haemophilus influenzae and Haemophilus haemolyticus by microarray-based hybridization
    Kirk W McCrea
    Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109 0244, USA
    J Clin Microbiol 48:714-9. 2010
    The sodC gene has been reported to be a useful marker for differentiating nontypeable (NT) Haemophilus influenzae from Haemophilus haemolyticus in respiratory-tract samples, but discrepancies exist as to the prevalence of sodC in NT H...
  41. pmc Haemophilus aphrophilus endocarditis after tongue piercing
    Hossein Akhondi
    Mercer School of Medicine, Savannah, Georgia 31404, USA
    Emerg Infect Dis 8:850-1. 2002
    ....
  42. ncbi Epidural abscess caused by Haemophilus aphrophilus misidentified as Pasteurella species
    Jui Teng Chien
    Department of Orthopedics, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan, ROC
    Intern Med 48:853-8. 2009
    b>Haemophilus aphrophilus is one of the normal oropharyngeal flora and rarely implicated as a pathogen of spinal infection. A case of H...
  43. ncbi Contact-dependent acquisition of transferrin-bound iron by two strains of Haemophilus parasuis
    N Charland
    Department of Microbiology, McGill University, Ste Anne de Bellevue, Canada
    Can J Microbiol 41:70-4. 1995
    Two strains of Haemophilus parasuis, namely, the type strain (ATCC 19417) and strain E751, were investigated with respect to iron acquisition...
  44. ncbi Airway bacterial concentrations and exacerbations of chronic obstructive pulmonary disease
    Sanjay Sethi
    Veterans Affairs Western New York Healthcare System 151, 3495 Bailey Avenue, Buffalo, NY 14215, USA
    Am J Respir Crit Care Med 176:356-61. 2007
    ..Bacterial concentrations are higher during exacerbation than during stable disease; however, these studies are cross sectional and devoid of strain typing...
  45. ncbi Development of a PCR test to diagnose Haemophilus parasuis infections
    S Oliveira
    Clinical and Population Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul 55108, USA
    J Vet Diagn Invest 13:495-501. 2001
    A polymerase chain reaction (PCR) test was developed in order to improve the accuracy and speed of diagnosis of Haemophilus parasuis, an economically important respiratory pathogen that affects swine...
  46. ncbi Protection of vaccinated pigs against experimental infections with homologous and heterologous Haemophilus parasuis
    H Bak
    Intervet Danmark, Skovlunde
    Vet Rec 151:502-5. 2002
    The efficacy of a new Haemophilus parasuis vaccine for pigs was investigated. The vaccine contains H parasuis serotype 5 cells and is adjuvanted with Diluvac Forte (Intervet)...
  47. pmc Naturally-farrowed, artificially-reared pigs as an alternative model for experimental infection by Haemophilus parasuis
    Simone Oliveira
    Department of Clinical and Population Sciences, College of Veterinary Medicine, University of Minnesota, 1988 Fitch Ave, Animal Science Veterinary Medicine Building, Saint Paul, Minnesota 55108, USA
    Can J Vet Res 67:146-50. 2003
    The use of naturally-farrowed, artificially-reared piglets as an alternative model to study Haemophilus parasuis infections was evaluated. Two trials were performed in order to evaluate the proposed model...
  48. ncbi Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nov., comb. nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter
    Niels Nørskov-Lauritsen
    Department of Clinical Microbiology, Aarhus University Hospital Skejby, DK 8200 Aarhus N, Denmark
    Int J Syst Evol Microbiol 56:2135-46. 2006
    ..the relationships and the generic affiliations of the species Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis...
  49. ncbi Inhibition of bovine macrophage and polymorphonuclear leukocyte superoxide anion production by Haemophilus somnus
    Michael D Howard
    Center for Molecular Medicine and Infectious Diseases, Virginia Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061 0342, USA
    Microb Pathog 37:263-71. 2004
    Virulent strains of the bovine opportunistic pathogen Haemophilus somnus (Histophilus somni) cause multi-systemic diseases in cattle. One of the reported virulence factors that H...
  50. ncbi A cross-protection experiment in pigs vaccinated with Haemophilus parasuis serovars 2 and 5 bacterins, and evaluation of a bivalent vaccine under laboratory and field conditions
    K Takahashi
    Nippon Institute for Biological Science, Ome, Tokyo, Japan
    J Vet Med Sci 63:487-91. 2001
    Cross-protection between Haemophilus parasuis serovars 2 and 5 was examined in pigs using a bacterin based vaccine, and subsequently the safety and efficacy of a bivalent vaccine were evaluated...
  51. ncbi Utilization of enterobactin and other exogenous iron sources by Haemophilus influenzae, H. parainfluenzae and H. paraphrophilus
    P Williams
    Department of Pharmaceutical Sciences, University of Nottingham, UK
    J Gen Microbiol 136:2343-50. 1990
    The ability of Haemophilus influenzae, H. parainfluenzae and H. paraphrophilus to utilize iron complexes, iron-proteins and exogenous microbial siderophores was evaluated...
  52. pmc Cloning and analysis of the genes encoding the type IIS restriction-modification system HphI from Haemophilus parahaemolyticus
    A Lubys
    Institute of Biotechnology, Vilnius, Lithuania
    Nucleic Acids Res 24:2760-6. 1996
    ..R-M) system HphI (enzymes recognizing the asymmetric sequence 5'-GGTGA-3'/5'-TCACC-3') from Haemophilus parahaemolyticus were cloned into Escherichia coli and sequenced...
  53. ncbi Development of a Haemophilus two-dimensional protein database
    P Cash
    Department of Medical Microbiology, University of Aberdeen, Foresterhill, UK
    Electrophoresis 18:1472-82. 1997
    Members of the Haemophilus genus are responsible for various human infections including respiratory infections and meningitis...
  54. pmc Haemophilus somnus immunoglobulin binding proteins and surface fibrils
    L B Corbeil
    Department of Pathology, University of California, San Diego 92103 8416, USA
    Infect Immun 65:4250-7. 1997
    The high-molecular-weight (HMW) immunoglobulin binding proteins (IgBPs) of Haemophilus somnus and a 76-kDa surface protein (p76) are found in serum-resistant virulent strains but not in several serum-sensitive strains from asymptomatic ..
  55. pmc The Neisseria gonorrhoeae S.NgoVIII restriction/modification system: a type IIs system homologous to the Haemophilus parahaemolyticus HphI restriction/modification system
    J S Gunn
    University of Maryland, Department of Microbiology, College Park, MD 20142, USA
    Nucleic Acids Res 25:4147-52. 1997
    ..the dcmH and damH genes, as well as an open reading frame downstream of the damH gene are highly similar to the Haemophilus parahaemolyticus hphIMC , hphIMA and hphIR gene products, encoding the Hph I Type IIs R-M system. The S...
  56. pmc The tryptophanase gene cluster of Haemophilus influenzae type b: evidence for horizontal gene transfer
    K Martin
    Division of Biological Sciences, University of Missouri, Columbia 65211, USA
    J Bacteriol 180:107-18. 1998
    Among strains of Haemophilus influenzae, the ability to catabolize tryptophan (as detected by indole production) varies and is correlated with pathogenicity...
  57. pmc Sequence and functional analyses of Haemophilus spp. genomic islands
    Mario Juhas
    Clinical Microbiology and Infectious Diseases, NDCLS, University of Oxford, Headley Way, Oxford OX3 9DU, UK
    Genome Biol 8:R237. 2007
    ..genomic islands among the Proteobacteria, recognized from the investigation of the evolutionary origins of a Haemophilus influenzae antibiotic resistance island, namely ICEHin1056...
  58. ncbi Porcine reproductive and respiratory syndrome virus and Haemophilus parasuis antigen distribution in dually infected pigs
    J Segales
    U D Anatomia Patològica, Facultat de Veterinaria, Universitat Autonoma de Barcelona, Spain
    Vet Microbiol 64:287-97. 1999
    ..to study the distribution and localization of porcine reproductive and respiratory syndrome virus (PRRSV) and Haemophilus (H.) parasuis in experimentally infected pigs. Thirty pigs seronegative to PRRSV and H...
  59. ncbi Multilocus sequence phylogenetic study of the genus Haemophilus with description of Haemophilus pittmaniae sp. nov
    Niels Nørskov-Lauritsen
    Department of Clinical Microbiology, Aarhus University Hospital, DK 8000 Aarhus, Denmark
    Int J Syst Evol Microbiol 55:449-56. 2005
    The phylogeny of human isolates of Haemophilus species was estimated based on partial sequences of four separate housekeeping genes...
  60. pmc Haemophilus somnus induces apoptosis in bovine endothelial cells in vitro
    M J Sylte
    Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin 63706, USA
    Infect Immun 69:1650-60. 2001
    b>Haemophilus somnus causes pneumonia, reproductive failure, infectious myocarditis, thrombotic meningoencephalitis, and other diseases in cattle. Although vasculitis is commonly seen as a result of systemic H...
  61. pmc Plasmid-encoded Tet B tetracycline resistance in Haemophilus parasuis
    John F Lancashire
    School of Molecular and Microbial Sciences, University of Queensland, Brisbane 4072, Australia
    Antimicrob Agents Chemother 49:1927-31. 2005
    The complete sequence of two plasmids, pHS-Tet (5.1 kb) and pHS-Rec (9.5 kb), isolated from Haemophilus parasuis strain HS1543 has been obtained...
  62. ncbi Neuraminidase (sialidase) activity of Haemophilus parasuis
    C A Lichtensteiger
    Department of Veterinary Pathobiology MC 002, College of Veterinary Medicine, University of Illinois, Urbana 61802, USA
    FEMS Microbiol Lett 152:269-74. 1997
    Neuraminidase (sialidase), a potential virulence factor in bacteria, was demonstrated in Haemophilus parasuis, an invasive swine pathogen, but not in four other pathogens of the Pasteurellaceae family: H. influenzae, H. somnus, H...
  63. pmc Molecular cloning, nucleotide sequence, and characterization of lppB, encoding an antigenic 40-kilodalton lipoprotein of Haemophilus somnus
    M Theisen
    Veterinary Infectious Disease Organization, Canadian Bacterial Diseases Network, Saskatoon, Saskatchewan
    Infect Immun 61:1793-8. 1993
    b>Haemophilus somnus is a facultative intracellular pathogen which causes a wide range of diseases in cattle. To identify putative virulence determinants, a genomic library of H...
  64. pmc The hbpA gene of Haemophilus influenzae type b encodes a heme-binding lipoprotein conserved among heme-dependent Haemophilus species
    M S Hanson
    Department of Microbiology, University of Texas Southwestern Medical Center, Dallas 75235 9048
    Infect Immun 60:2257-66. 1992
    A membrane-associated lipoprotein of Haemophilus influenzae type b has previously been shown to bind heme in vitro and to promote binding of this compound by Escherichia coli recombinants expressing this protein. The H...
  65. ncbi Tetrameric repeat units associated with virulence factor phase variation in Haemophilus also occur in Neisseria spp. and Moraxella catarrhalis
    I R Peak
    Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, UK ipeak mobiol ox ac uk
    FEMS Microbiol Lett 137:109-14. 1996
    ..and 5'-GCAA-3' are associated with phase variable expression of lipopolysaccharide biosynthetic genes in Haemophilus influenzae. Four other tetrameric repeat units have also been reported from H...
  66. pmc Levels of nicotinamide adenine dinucleotide in extracellular body fluids of pigs may be growth-limiting for Actinobacillus pleuropneumoniae and Haemophilus parasuis
    Terence O'Reilly
    Department of Natural Resource Sciences, McGill University, Macdonald Campus, 21111 Lakeshore Road, Ste Anne de Bellevue, Quebec H9X 3V9
    Can J Vet Res 67:229-31. 2003
    ..Actinobacillus pleuropneumoniae (biotype 1) and Haemophilus parasuis, respiratory tract pathogens of swine, are both V-factor-dependent...
  67. pmc Typing of nonencapsulated haemophilus strains by repetitive-element sequence-based PCR using intergenic dyad sequences
    Guillaume Bruant
    Département de Microbiologie Médicale et Moléculaire, Unité de Bactériologie, Centre Hospitalo Universitaire Bretonneau, 37044 Tours Cedex, France
    J Clin Microbiol 41:3473-80. 2003
    Intergenic dyad sequences (IDS) are short repeated elements that have been described for several Haemophilus genomes and for only two other bacterial genera...
  68. ncbi Analysis of exotoxins produced by atypical isolates of Aeromonas salmonicida, by enzymatic and serological methods
    B K Gudmundsdottir
    Institute for Experimental Pathology, University of Iceland, Reykjavik, Iceland
    J Fish Dis 26:15-29. 2003
    In this study, exotoxins produced by 62 Aeromonas salmonicida strains and the bacterium Haemophilus piscium were analysed...
  69. ncbi [Haemophilus spp. antimicrobial susceptibility in Health Area 6 in Madrid, Spain (2000-2004)]
    B Orden Martínez
    Servicio de Microbiologia, Hospital Universitario Puerta de Hierro Centro de Especialidades Argüelles, Madrid, Spain
    Rev Esp Quimioter 18:173-8. 2005
    The aim of this study was to assess the antimicrobial susceptibility of 1370 Haemophilus spp. (1051 H. influenzae and 319 H...
  70. ncbi Efficacy of a new tetravalent coryza vaccine against emerging variant type B strains
    Anton A C Jacobs
    Intervet International BV 5830 P O Box 31 AA Boxmeer, The Netherlands
    Avian Pathol 32:265-9. 2003
    ..coryza have been reported in vaccinated flocks in different countries, indicating that new serotype(s) of Haemophilus paragallinarum may have evolved...
  71. ncbi Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 16-2003. A 58-year-old woman with left-sided weakness and a right frontal brain mass
    Robert M Friedlander
    Department of Neurosurgery, Brigham and Women s Hospital, Boston, USA
    N Engl J Med 348:2125-32. 2003
  72. ncbi Infections with Haemophilus species in chronic granulomatous disease: insights into the interaction of bacterial catalase and H2O2 production
    S Kottilil
    Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD 20892, USA
    Clin Immunol 106:226-30. 2003
    ..Typically these patients are susceptible to life-threatening infections with catalase-producing organisms. Haemophilus species, particularly H...
  73. ncbi Actinobacillus actinomycetemcomitans and Haemophilus aphrophilus in systemic and nonoral infections in Finland
    Susanna Paju
    Institute of Dentistry, University of Helsinki, Finland
    APMIS 111:653-7. 2003
    The oral cavity is the ecological niche for Actinobacillus actinomycetemcomitans and Haemophilus aphrophilus, but occasionally they cause severe nonoral infections. In this study we present 20 systemic or nonoral infections due to A...
  74. ncbi Rat strains differ in antibody response to natural Haemophilus species infection
    R Boot
    Section of Laboratory Animal Microbiology, Diagnostic Laboratory for Infectious Diseases and Perinatal Screening, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Lab Anim 39:413-20. 2005
    Antibody response to Haemophilus species in rat strains was monitored by enzyme-linked immunosorbent assay (ELISA) using antigens of two Haemophilus strains and a Pasteurella pneumotropica strain...
  75. ncbi Infective endocarditis due to Haemophilus aphrophilus: a case report
    Ricardo M Pereira
    Enfermaria de Pediatria, Hospital de Clinicas, Universidade de Campinas UNICAMP, Campinas, SP, Brazil
    J Pediatr (Rio J) 84:178-80. 2008
    To report the case of a child with infective endocarditis caused by Haemophilus aphrophilus.
  76. ncbi A case of Haemophilus aphrophilus and Mobiluncus mulieris hepatic abscess
    M Sherlock
    Department of Diabetes and Endocrinology, Beaumont Hospital, Beaumont Road, Dublin 9, Republic of Ireland
    J Infect 51:E19-22. 2005
  77. ncbi [Shoulder arthritis due to Haemophilus aphrophilus]
    M A Bouldouyre
    Laboratoire de Microbiologie, Fondation Hopital Saint Joseph, 185 rue Raymond Losserand, 75674 Paris Cedex 14, France
    Med Mal Infect 35:367-9. 2005
    We report a case of shoulder arthritis due to Haemophilus aphrophilus. The patient, a 56 year-old woman, was immunocompetent. She presented with a septic arthritis of the left shoulder without portal of entry...
  78. doi Autopsy of bacterial vaginosis: a physiological entity rather than a contagious disease
    Pentti A Leppäluoto
    Acta Obstet Gynecol Scand 87:578-9. 2008
  79. ncbi Suppurative rhinitis associated with Haemophilus species infection in a cat
    R J Milner
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, PO Box 100126, Gainesville, FL 32610 0126, USA
    J S Afr Vet Assoc 75:103-7. 2004
    ..Initial diagnostics were significant for the isolation of an unusual pathogen, Haemophilus species. Isolation using a human RapID NH system erroneously identified the isolate as H...
  80. pmc Characterization of Haemophilus segnis, an important cause of bacteremia, by 16S rRNA gene sequencing
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 42:877-80. 2004
    We describe the application of 16S rRNA gene sequencing in defining eight cases of bacteremia due to Haemophilus species other than Haemophilus influenzae (non-H. influenzae bacteremia) during a 7-year period...
  81. ncbi Clinical profile of pleural empyema and associated factors with prolonged hospitalization in paediatric tertiary centre in Angola, Luanda
    Murilo Carlos Amorim de Britto
    IMIP Paediatric Respiratory Diseases, Rua dos Coelhos, 300 Boa Vista Recife, Pernambuco 50070550, Brazil
    Trop Doct 38:118-20. 2008
    ..The median for hospital stay was 25 days. The lethality was 7.8% and was not statistically associated with malnutrition, although this variable was associated, in multivariate analysis, with prolonged hospitalization time...
  82. pmc Reduced levofloxacin susceptibility and tetracycline resistance in a clinical isolate of Haemophilus quentini identified by 16S rRNA sequencing
    Gannon C Mak
    Centre of Infection and Department of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China
    J Clin Microbiol 43:5391-2. 2005
    This paper reports the first case of Haemophilus quentini bacteremia with reduced susceptibility to levofloxacin and resistance to nalidixic acid identified by 16S rRNA sequencing...
  83. ncbi [Isolated pathogen microorganisms in respiratory samples from children with cystic fibrosis]
    M M Anzaudo
    Sección Bacteriología del Hospital de Niños Dr Orlando Alassia Mendoza 4151, 3000, Santa Fe, Argentina
    Rev Argent Microbiol 37:129-34. 2005
    ..Chronic respiratory tract colonization is caused mainly by bacteria such as Staphylococcus aureus, Haemophilus spp. and Pseudomonas aeruginosa...
  84. ncbi Haemophilus aphrophilus brain abscess in the first decade
    M Bayraktar
    Inonu University, Faculty of Medicine, Turgut Ozal Medical Center, Deptartment of Clinical Microbiology, Malatya, Turkey
    Indian J Med Microbiol 23:259-61. 2005
    This report presents a case of brain abscess due to Haemophilus aphrophilus in a six-year old boy. He was admitted to our hospital suffering from left-sided weakness. The initial radiological diagnosis was an intracranial abscess...
  85. ncbi [Infective endocarditis due to HACEK group bacteria]
    Kenichi Nakamura
    Department of General Medicine, Aso Iizuka Hospital, Iizuka
    Nihon Naika Gakkai Zasshi 92:1521-3. 2003
  86. ncbi Brain nodules with lung mass: are they always metastases?
    Sandra Jorcano
    Department of Radiation Oncology, Hospital Clinic Universitari, IDIBAPS Institut d Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain
    Clin Transl Oncol 10:512-4. 2008
    ..This case illustrates the advisability of always obtaining histological diagnosis of the primary tumor and/or cerebral lesion before introducing any oncological treatment...
  87. ncbi Haemophilus segnis: a rare cause of endocarditis
    C J Somers
    Department of Microbiology, The Laboratories, The Adelaide and Meath Hospital, Dublin 24, Ireland, UK
    Clin Microbiol Infect 9:1048-50. 2003
    This report presents a case of endocarditis due to Haemophilus segnis, which represents a speciation difficulty for the routine laboratory...
  88. ncbi Haemophilus parainfluenzae infection of respiratory mucosa
    A M Middleton
    Host Defence Unit, Royal Brompton Hospital, Sydney Street, London UK
    Respir Med 97:375-81. 2003
    The pathogenicity of Haemophilus parainfluenzae (Hpi) in the respiratory tract is unclear, in contrast to the accepted pathogenicity of its close relative non-typable H. influenzae...
  89. ncbi Vertebral infections caused by Haemophilus aphrophilus: case report and review
    P Colson
    , Center Hospitalo-Universitaire Timone, Marseille, France
    Clin Microbiol Infect 7:107-13. 2001
    ..To review in detail clinical presentation, bacteriologic findings, associated conditions and treatment of Haemophilus aphrophilus vertebral osteomyelitis and to compare them to a case we report herein...
  90. ncbi Gardnerella vaginalis is associated with other sexually transmittable microorganisms in the male urethra
    P Elsner
    ,
    Zentralbl Bakteriol Mikrobiol Hyg A 269:56-63. 1988
    ..vaginalis, U. urealyticum and G. vaginalis, M. hominis and U. urealyticum, M. hominis. It is concluded that G. vaginalis is associated with genital mycoplasmas not only in the female, but also in the male urogenital tract...
  91. ncbi Histamine production by Haemophilus somnus
    Kevin W Ruby
    US Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, Center for Veterinary Biologics, Licensing and Policy Development, Ames, IA 50010, USA
    Comp Immunol Microbiol Infect Dis 25:13-20. 2002
    Ten Haemophilus somnus isolates were grown on blood agar plates under a 5% CO2 atmosphere for 48 h. Harvested whole cells were washed and evaluated for the presence of histamine by ELISA. All H...
  92. ncbi [Haemophilus aphrophilus isolated from the blood of a patient with infective endocarditis]
    I Yoshioka
    Department of Medical Laboratory, Kansai Denryoku Hospital
    Kansenshogaku Zasshi 69:777-84. 1995
    ..For the correct identification of H. aphrophilus strains, fermentation test of glucose, lactose, maltose and sucrose in either phenol red broth or CTA medium are necessary.(ABSTRACT TRUNCATED AT 250 WORDS)..
  93. ncbi Haemophilus parainfluenzae complicating total hip arthroplasty: a rapid failure
    P A Jellicoe
    Department of Orthopaedics, York District Hospital, Yorkshire, United Kingdom
    J Arthroplasty 17:114-6. 2002
    We present a case of rapid failure of a total hip arthroplasty caused by infection with Haemophilus parainfluenzae...
  94. pmc Standardization of broth microdilution and disk diffusion susceptibility tests for Actinobacillus pleuropneumoniae and Haemophilus somnus: quality control standards for ceftiofur, enrofloxacin, florfenicol, gentamicin, penicillin, tetracycline, tilmicosin
    P F McDermott
    Division of Animal and Food Microbiology, Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, Maryland 20708, USA
    J Clin Microbiol 39:4283-7. 2001
    ..susceptibility testing of two fastidious veterinary pathogens, Actinobacillus pleuropneumoniae and Haemophilus somnus, were developed in a multilaboratory study according to procedures established by the National Committee ..
  95. ncbi Haemophilus somnus bronchopneumonia in American bison (Bison bison)
    N W Dyer
    Department of Veterinary and Microbiological Sciences, Veterinary Diagnostic Laboratory, Fargo, ND 58105, USA
    J Vet Diagn Invest 13:419-21. 2001
    ..Seven of the 21 bison had positive staining for Haemophilus somnus in alveolar exudate, visceral pleura, lung parenchyma, and chronic necrotic lesions, and H...
  96. ncbi Serotyping of Haemophilus paragallinarum isolates from Mexico by the Kume hemagglutinin scheme
    V E Soriano
    , Facultad de Medicina Veterinaria y Zootecnia, , Toluca
    Avian Dis 45:680-3. 2001
    A total of 42 isolates of Haemophilus paragallinarum from Mexico were serotyped by the Kume hemagglutinin scheme. Serovars A-1, A-2, B-1, and C-2 were recognized among 11 (26.2%), 7 (16.6%), 4 (9.5%), and 14 (33...
  97. ncbi Isolation of Haemophilus somnus from dairy cattle in kwaZulu-Natal. An emerging cause of 'dirty cow syndrome' and infertility?
    R D Last
    Vetdiagnostix Veterinary Pathology Services, Cascades, South Africa
    J S Afr Vet Assoc 72:95. 2001
    b>Haemophilus somnus was consistently isolated from vaginal discharges of dairy cows submitted from field cases of vaginitis, cervicitis and/or metritis in the KwaZulu-Natal Midlands during the period July 1995 - December 2000 and from the ..
  98. ncbi Spinal abscess of Haemophilus paraphrophilus. A case report
    W Samuel
    Department of Orthopaedic Surgery, Royal Hampshire County Hospital, Winchester and Eastleigh Healthcare NHS Trust, United Kingdom
    Spine (Phila Pa 1976) 22:2763-5. 1997
    STUDY DESIGN: A case of paraspinal abscess formation from Haemophilus paraphrophilus is presented. OBJECTIVES: To describe a case of paraspinal abscess formation from H...
  99. pmc Experimental colonization of piglets and gilts with systemic strains of Haemophilus parasuis and Streptococcus suis to prevent disease
    S Oliveira
    Department of Clinical and Population Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul 55108, USA
    Can J Vet Res 65:161-7. 2001
    b>Haemophilus parasuis and Streptococcus suis are both major causes of losses during the nursery period, especially in herds using the segregated early weaning system...
  100. ncbi Isolation of Haemophilus parahaemolyticus in a patient with cryptogenic brain abscess
    C C Chen
    Department of Internal Medicine, Taipei Veterans General Hospital, National Yang-Ming School of Medicine, Taiwan
    Scand J Infect Dis 33:385-6. 2001
    b>Haemophilus parahaemolyticus rarely causes disease in humans. We present the case of a 68-y-old man who suffered from a brain abscess over the right-side thalamus and midbrain. Stereotactic aspirates grew H. parahaemolyticus...
  101. ncbi Thromboembolic meningoencephalitis due to Haemophilus somnus in feedlot cattle in Argentina
    C O Descarga
    Marcos Juárez, Province of Córdoba, Argentina
    Vet Rec 150:817. 2002

Research Grants67

  1. Global regulatory interactions in bacterial pathogenesis
    BRIAN AKERLEY; Fiscal Year: 2009
    ..b>Haemophilus influenzae provides a genetically tractable model to examine this aspect of pathogenesis. H...
  2. Anti-Bacterial Innate Responses Enhance Paramyxovirus Replication
    Griffith D Parks; Fiscal Year: 2010
    ..In Aim 3, we will establish in vitro bacterial biofilms with nontypeable Haemophilus influenzae (NTHi) or with Streptococcus pneumoniae (pneumococcus) and determine the viral replication potential ..
  3. Epidemiology and Etiology of Hospitalized Pneumonia in Children
    Krow Ampofo; Fiscal Year: 2010
    ..Moreover, the epidemiology of childhood pneumonia is changing due to the impact of Haemophilus influenzae type b (Hib) vaccine and pneumococcal conjugate vaccine, and the emergence of non-vaccine serotypes ..
  4. MNEI/SerpinB1: A modulator of innate pulmonary defense
    EILEEN REMOLD-O'DONNELL; Fiscal Year: 2010
    ..aeruginosa, Haemophilus influenzae) and Gram-positive (Staphylococcus aureus) organisms and in two genetic backgrounds (C57BL/6 ..
  5. Mechanisms of Haemophilus influenzae pathogenesis in the lung
    Hao Shen; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The bacterium Haemophilus influenzae inhabits the human nasopharynx and conjunctiva, and can disseminate to cause pneumonia, otitis media, or meningitis...
  6. Antimicrobial Peptides and Innate Immunity in Otitis Media
    Lauren O Bakaletz; Fiscal Year: 2012
    ..e. during colonization) at the level of the molecular crosstalk that occurs between nontypeable Haemophilus influenzae (NTHI) and the mucosal epithelium of the NP;2) the polymicrobial disease OM (i.e...
  7. Haemophilus influenzae iron/heme regulon
    Terrence L Stull; Fiscal Year: 2012
    ABSTRACT Current vaccines against Haemophilus influenzae type b have reduced the incidence of H. influenzae type b invasive diseases...
  8. Novel immunotherapeutics for the management of otitis media due to H. influenzae
    Steven D Goodman; Fiscal Year: 2013
    ..tremendous recent advances in our understanding of the pathogenesis of otitis media (OM) due to nontypeable Haemophilus influenzae (NTHI)...
  9. CT EIP Capacities ACA Grant
    TRACEY L WEEKS; Fiscal Year: 2011
    ..meningitidis, Listeria monocytogenes, Haemophilus influenzae). We are requesting funding for a ...
  10. Novel biofilm polymicrobial infection-resistant implants for otologic application
    Paul Stoodley; Fiscal Year: 2010
    ..the release kinetics of our new materials and to injection mold TTs, 2) to confirm our in vitro studies with Haemophilus influenzae and Streptococcus pneumoniae, and quantify synergy and monitor for the development of resistant ..
  11. Structures of RNA processing and Silencing Enzymes in Prokaryotes
    Hong Li; Fiscal Year: 2013
    ..in medically important bacteria that include but not limited to Yersinia pestis, Mycobacterium tuberculosis, Haemophilus influenzae, Helicobacter pylori, Neisseria meningitides, Vibrio vulnificus, Staphylococcus aureus, Salmonella ..
  12. Regulation of NETosis in antibacterial lung defense
    EILEEN REMOLD-O'DONNELL; Fiscal Year: 2013
    ..provided by applicant): Pneumonias resulting from failure to eradicate bacterial (Streptococcus pneumonia, Haemophilus influenza, Staphylococcus aureus, Pseudomonas aeruginosa) and viral (rhinovirus, influenza virus) infections ..
  13. Respiratory Panel Flow-Strip: a Point-of-Care Molecular Diagnostic Test
    CHRISTOPHER GERARD COONEY; Fiscal Year: 2012
    ..metapneumovirus, human rhinovirus A/B/C, human bocavirus 1/2/3/4, human parainfluenza virus 1/2/3/4, Haemophilus influenzae, Streptococcus pneumoniae, Mycoplasma pneumoniae, Chlamydophila pneumoniae, Legionella pneumophila, ..
  14. H. influenzae: Role of Sialic Acid in Virulence
    Michael A Apicella; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Nontypeable Haemophilus influenzae (NTHi) commonly colonize the mucosal surfaces of the human upper respiratory tract...
  15. Biology of the HMW1 and HMW2 Adhesins of H. Influenzae
    JOSEPH W ST. GEME; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Nontypable Haemophilus influenzae is a common cause of localized respiratory tract disease, especially otitis media, sinusitis, pneumonia, and exacerbations of chronic lung disease...
  16. H. influenzae: Role of Sialic Acid in Virulence
    Michael Apicella; Fiscal Year: 2009
    Project Summary/Abstract: Nontypeable Haemophilus influenzae (NTHi) commonly colonize the mucosal surfaces of the human upper respiratory tract...
  17. DETERMINANTS OF H. INFLUENZAE VIRULENCE IN OTITIS MEDIA
    Lauren O Bakaletz; Fiscal Year: 2013
    ..Streptococcus pneumoniae, the relative proportion of cases of OM due to our studied microorganism (nontypeable Haemophilus influenzae or NTHI) has increased significantly...
  18. Mechanisms of Haemophilus influenzae pathogenesis in the lung
    Hao Shen; Fiscal Year: 2011
    Project Summary/Abstract The bacterium Haemophilus influenzae inhabits the human nasopharynx and conjunctiva, and can disseminate to cause pneumonia, otitis media, or meningitis...
  19. Heme, Iron and Oxidative Stress: Regulation of Iron Homeostasis in H. Influenzae
    Robert S Munson; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Nontypeable Haemophilus influenzae (NTHi) is a significant human pathogen as it is a major cause of otitis media (OM), sinusitis, exacerbations of chronic obstructive pulmonary disease (COPD) and ..
  20. H. influenzae Genes Associated with Acute Otitis Media
    Janet R Gilsdorf; Fiscal Year: 2010
    ..Previous studies suggest that non-typeable Haemophilus influenza (NTHi), an important cause of acute otitis media in children, possess unique genes important in the ..
  21. Genetics &Biology of M. catarrhalis LOS in Otitis Media
    Anthony A Campagnari; Fiscal Year: 2013
    ..e. Neisseria meningitidis, N. gonorrhoeae and Haemophilus influenzae. More importantly, these common carbohydrate epitopes are involved in virulence, i.e...
  22. Immune Responses in Otitis Prone Children
    Michael E Pichichero; Fiscal Year: 2013
    ..and innate immune response deficits among otitis prone (OP) children to infections caused by nontypeable Haemophilus influenzae (NTHi) and Streptococcus pneumoniae (Spn)...
  23. Training in Sexually Transmitted Diseases Including HIV
    Stanley M Spinola; Fiscal Year: 2013
    ..These mentors work on HPV, Haemophilus ducreyi, basic aspects of HIV-1, epidemiology, vaccines, behavioral factors that lead to acquisition of STDs, ..
  24. Innate and adaptive immune responses at the respiratory mucosa
    Yasmin Thanavala; Fiscal Year: 2010
    ..immune responses in the lung using mouse adapted respiratory syncytial virus (RSV) and non-typeable Haemophilus influenzae (NTHI) a gram negative bacterium...
  25. Grafting DNA Codes on Paper for Rapid, Low-Cost, and Sensitive Meningitis Diagnos
    Xiujun Li; Fiscal Year: 2013
    ..and highly-sensitive diagnosis of three different types of bacterial meningitis, namely Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumonia especially for resource-poor settings...
  26. Regulation of Inflammation by EGFR in Otitis Media
    Xiangbin Xu; Fiscal Year: 2012
    ..Inflammation in the middle ear caused by microorganisms is a hallmark of OM. Nontypeable Haemophilus influenzae (NTHi) is an important human pathogen that causes OM...
  27. Effect of breast feeding on immunologic priming in young infants.
    John W Sleasman; Fiscal Year: 2013
    ..Studies will focus on the response to the conjugated vaccines against Haemophilus influenza (HIb) and Streptococcus pneumonia [Prevnar 13(R)]...
  28. PROTEIN/LIPID INTERACTIONS
    Robert B Gennis; Fiscal Year: 2013
    ..will focus on 1) Mycobacterium tuberculosis, which requires cytochrome bd in the persistent (dormant) state;2) Haemophilus influenzae, for which cytochrome bd has been recently shown to be essential for growth;and 3) Neisseria ..
  29. Laser-based powder vaccine delivery for improved newborn immunization
    Xinyuan Chen; Fiscal Year: 2013
    ..Polysaccharide-encapsulated bacteria, such as Haemophilus influenzae type b (Hib), are leading causes of serious infections in infants...
  30. The extent and limits of natural transformation in Haemophilus influenzae
    Joshua Chang Mell; Fiscal Year: 2013
    ..One of these pathogens, Haemophilus influenzae, inhabits the upper respiratory tract of most people, usually with no negative effect, but can cause ..
  31. PATHOGENESIS OF HAEMOPHILUS DUCREYI INFECTIONS
    Stanley M Spinola; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Haemophilus ducreyi is a strict human pathogen that causes chancroid, a genital ulcer disease (GUD) that facilitates the transmission of the human immunodeficiency virus (HIV-1)...
  32. IgA Protease as Therapy to Reverse IgA Nephropathy
    Jiazhou Qiu; Fiscal Year: 2012
    ..We will develop IgA protease of Haemophilus influenzae as an injectable biological therapeutic for this purpose...
  33. Innate and adaptive immune response to bacterial infections in COPD patients
    Yasmin Thanavala; Fiscal Year: 2009
    ..tree is sterile, however in COPD patients it is chronically colonized, predominantly with nontypeable Haemophilus influenzae (NTHI), Moraxella catarrhalis and Streptococcus pneumoniae...
  34. Innate Immunity in Otitis Media Pathogenesis
    David J Lim; Fiscal Year: 2013
    ..pneumoniae vaccination emphasizes the clinical importance of nontypeable Haemophilus influenzae (NTHi), which is the focus of this proposal...
  35. Airway Metalloproteinases in Mucosal Immunity
    CAROLE LYNN WILSON; Fiscal Year: 2010
    ..Infection of the lung by various pathogens (e.g., Staphylococcus aureus, haemophilus influenzae, Pseudomonas aeruginosa, and other) are a major cause of community-acquired infection and morbidity ..
  36. Heme Scavenging and Uptake by Haemophilus ducreyi
    EDWARD JOHN COLLINS; Fiscal Year: 2011
    ..One such mechanism is the expression of cell surface receptors specific for host heme-containing proteins. Haemophilus ducreyi, the causative agent of the sexually transmitted genital ulcer disease chancroid, expresses only one ..
  37. Computing Infrastructure to Advance Biomedical Research
    THOMAS FURLANI; Fiscal Year: 2010
    ..for invasive MRSA infections, the incidence of which has surpassed those of prevalent pathogens such as Haemophilus influenza and Streptococcus pneumonia, (4) regulatory genomics aimed at understanding the biochemistry of gene ..
  38. Persistent H. influenzae in COPD - virulence, vaccines and antibiotic resistance
    Timothy F Murphy; Fiscal Year: 2013
    ..has begun to elucidate the critical role of bacterial colonization and infection, particularly by nontypeable Haemophilus influenzae (NTHI), in the course and pathogenesis of COPD...
  39. A New Antibacterial Drug Target: Analyzing Inhibitor Binding to a Bacterial Metal
    Richard C Holz; Fiscal Year: 2010
    ..0 and 2.3 E resolution structures of the mono and dinuclear Zn(II) DapE enzymes from the pathogenic bacterium Haemophilus influenzae...
  40. DnaK Protein Inhibitor Antimicrobials
    Michael Sturgess; Fiscal Year: 2003
    ..studied for its ability to protect mice against systemic and local Klebsiella pneumoniae, Escherichia coli, Haemophilus influenzae, Moraxella catarrhalis and Salmonella typhimurium infections...
  41. Metabolic regulation in otitis media
    DAYLE ANITA DAINES; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Nonencapsulated (nontypeable) Haemophilus influenzae (NTHi) are human-adapted commensal organisms that can also cause chronic mucosal infections, particularly otitis media...
  42. Development of a vaccine for prevention of Haemophilus influenzae otitis media
    Stephen J Barenkamp; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Otitis media and other illnesses caused by nontypeable Haemophilus influenzae (NTHi) remain significant health problems for children and a vaccine for prevention of disease is much needed...
  43. Haemophilus ducreyi Inhibits Phagocytosis
    ERIC JOHN HANSEN; Fiscal Year: 2013
    b>Haemophilus ducreyi is the etiologic agent of chancroid, a sexually transmitted genital ulcer disease. Very little Is known about how this unencapsulated. Gram-negative bacterium evades host defenses and causes demrial lesion development...
  44. Therapeutics for Drug-Resistant Bacteria: Pseudouridimycins
    Richard H Ebright; Fiscal Year: 2013
    ..b>Haemophilus sp., and Moraxella sp...
  45. Effect of Haemophilus influenzae infection on lung CD8+ T cells in COPD
    CHRISTINE M BASMAJIAN; Fiscal Year: 2013
    ..TLR2/1 is known to recognize the outer membrane protein of nontypeable Haemophilus influenzae (NTHI), one of the predominant bacterial pathogens associated with airway infection in COPD, both in ..
  46. Protein-protein interaction essential for bacterial growth and virulence
    Mark A Saper; Fiscal Year: 2013
    ..Unlike E. coli K12, at least two pathogens require LpoA for virulence. Haemophilus in- fluenzae causes children's ear infections and exacerbates chronic obstructive pulmonary disorder (COPD)..
  47. Neutrophil Extracellular Traps and Haemophilus ducreyi
    Margaret E Bauer; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Haemophilus ducreyi is the causative agent of chancroid, a sexually transmitted genital ulcer disease that facilitates transmission and acquisition of human immunodeficiency virus (HIV) and thus ..
  48. Biennial Symposium of H. ducreyi Pathogenesis and Chancroid
    Stanley M Spinola; Fiscal Year: 2011
    DESCRIPTION (provided by applicant): Haemophilus ducreyi, which causes the genital ulcer disease chancroid, was overlooked as a significant cause of human disease until the late1980's, when several thousand cases of chancroid ..
  49. EMERGING INFECTIONS PROGRAM
    Paul R Cieslak; Fiscal Year: 2011
    ..invasive infectionby bacterialpathogens, includinggroups A and B streptococci,Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis,and for methicillin-resistantStaphylococcusaureus;for entericand ..
  50. Mechanisms of Sap-mediated Antimicrobial Peptide Resistance
    Margaret E Bauer; Fiscal Year: 2012
    ..Using the Sap transporter of Haemophilus ducreyi as a model system, we have begun to study the role of specific Sap proteins in conferring AP resistance...
  51. Southeastern Sexually Transmitted Infections Cooperative Research Center
    Philip Frederick Sparling; Fiscal Year: 2013
    ..is comprised of six projects Including studies on the sexually transmitted pathogens Neisseria gonorrhoeae and Haemophilus ducreyi...
  52. Haemophilus parainfluenzae and cardiopulmonary disease
    Wade A Nichols; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Haemophilus parainfluenzae is a Gram-negative pleomorphic bacillus that is found exclusively associated with human hosts...
  53. Peptide Derivatives to treat Urinary Tract Infections
    Laszlo Otvos; Fiscal Year: 2003
    ..tetracycline- and aminoglycoside-resistant Escherichia coli, Klebsiella pneumoniae, Salmonella typhimurium, and Haemophilus influenzae clinical isolates, among many others, in nanomolar or low micromolar concentrations...
  54. CIPRA-SA: Safeguard the household: comprehensive AIDS research: Extension
    JAMES ALASDAIR MCINTYRE; Fiscal Year: 2011
    ..n=180), (4) Evaluation of quantitative and qualitative antibody responses to Streptococcus pneumoniae and Haemophilus infiuenzae type b conjugate vaccines amongst HIV-1-exposed-infected children that are receiving vs...
  55. Microbial interactions in otitis media
    WILLIAM E SWORDS; Fiscal Year: 2013
    PROJECT SUMMARY This project aims to define how polymicrobial infection influences bacterial otitis media. Haemophilus influenzae (Hi), Streptococcus pneumoniae (Sp), and Moraxella catarrhalis (Mcat) are the predominant isolates from ..
  56. Bacterial biofilms in otitis media
    WILLIAM E SWORDS; Fiscal Year: 2013
    ..Otitis media is caused by airway opportunists such as Haemophilus influenzae (Hi, which forms biofilm communities that promote bacterial persistence within the middle-ear ..
  57. Haemophilus Hap-mediated Microcolony Formation
    JOSEPH ST GEME; Fiscal Year: 2002
    Nontypable Haemophilus influenzae is a common cause of localized respiratory tract disease, especially otitis media, sinusitis, bronchitis, and pneumonia...
  58. Quorum signal eavesdropping by Moraxella catarrhalis
    WILLIAM E SWORDS; Fiscal Year: 2013
    ..airway infections, and our data show that Mcat can sense dihydroxypentanedione (DPD) quorum signals produced by Haemophilus influenzae...
  59. DEVELOPMENT OF A FIMBRIN VACCINE AGAINST OTITIS MEDIA
    LAUREN BAKALETZ; Fiscal Year: 1999
    ..the pathogenesis of and immune response directed against one of the primary causative agents, nontypeable Haemophilus influenzae (NTHi), is poorly understood and a vaccine is not available...
  60. SEQUENCING OF THE HAEMOPHILUS DUCREYI GENOME
    Robert Munson; Fiscal Year: 1999
    b>Haemophilus ducreyi is the causative agent of chancroid, a sexually transmitted genital ulcerative disease. The World Health Organization estimates the annual incidence of chancroid to be over 9 million cases of per year...
  61. Genomic Sequence of an Otitis Media Isolate of NTHi
    Robert Munson; Fiscal Year: 2003
    At the current time, we have a poor understanding of how nontypeable Haemophilus influenzae (NTHi) cause otitis media (OM) in children...
  62. DNA SEQUENCE OF STAPHYLOCOCCUS AUREUS 8325 GENOME
    JOHN LANDOLO; Fiscal Year: 1999
    In 1995, Fleischman et al. (40) determined the nucleotide sequence of Haemophilus influenzae Rd without prior restriction site mapping and cosmid cloning...
  63. Haemophilus Hap-mediated Microcolony Formation
    JOSEPH ST GEME; Fiscal Year: 2007
    Nontypable Haemophilus influenzae is a common cause of localized respiratory tract disease, including otitis media, sinusitis, bronchitis, and pneumonia...
  64. GENETICS OF H. AEGYPTIUS BRAZILIAN PURPURIC FEVER CLONE
    Luis Actis; Fiscal Year: 2000
    Brazilian purpuric fever (BPF) is a fatal disease caused by a unique invasive clone of Haemophilus influenzae biogroup aegyptius (H. aegyptius), a bacterial species that is normally non-invasive and causes mild cases of conjunctivitis...
  65. NEW PHYSICAL METHODOLOGIES FOR GENOMIC ANALYSIS
    David C Schwartz; Fiscal Year: 2013
    ..g., mate-pair information was crucial to the success of the first prokaryotic genome project - Haemophilus influenza)...
  66. HAEMOPHILUS--RAMIFICATIONS OF PILUS MEDIATED ADHERENCE
    GRAHAM KRASAN; Fiscal Year: 2004
    b>Haemophilus influenzae is a pathogen that mediates a wide range of human disease including otitis media, sinusitis, and pneumonia often in association with an increased density of nasopharyngeal colonization...
  67. THE EFFICACY OF CONJUGATE VACCINES AGAINST H INFLUENZAE
    Eugene Shapiro; Fiscal Year: 1993
    b>Haemophilus influenzae type b is the most common cause of bacterial meningitis and other serious invasive bacterial infections in children...