Genomes and Genes
Summary: A genus of the family CHLAMYDIACEAE comprising gram-negative non CHLAMYDIA TRACHOMATIS-like species infecting vertebrates. Chlamydophila do not produce detectable quantities of glycogen. The type species is CHLAMYDOPHILA PSITTACI.
Publications190 found, 100 shown here
- Detection of Chlamydophila abortus in sheep and goat flocks in southern Italy by PCR using four different primer setsG Greco
Department of Animal Health and Wellbeing, Faculty of Veterinary Medicine, University of Bari, S p le per Casamassima Km 3, 70010 Valenzano, Bari, Italy
Vet Res Commun 29:107-15. 2005An epidemiological survey was performed to detect the presence of Chlamydophila (C.) abortus and other members of the order Chlamydiales in ovine and caprine flocks with a history of abortion in southern Italy...
- New real-time PCR tests for species-specific detection of Chlamydophila psittaci and Chlamydophila abortus from tissue samplesAlexandra Pantchev
Chemisches und Veterinaruntersuchungsamt Stuttgart, 70736 Fellbach, Fellbach, Germany
Vet J 181:145-50. 2009b>Chlamydophila psittaci and Chlamydophila abortus are the causative agents of avian chlamydiosis (psittacosis) and ovine enzootic abortion, respectively. Both pathogens are known to possess zoonotic potential...
- Chlamydophila species in dairy farms: polymerase chain reaction prevalence, disease association, and risk factors identified in a cross-sectional study in western GermanyK Kemmerling
Institute of Animal Science, University of Bonn, Bonn, Germany
J Dairy Sci 92:4347-54. 2009The prevalence of Chlamydophila spp. was determined in a cross-sectional study carried out in 2007 using 100 randomly selected dairy herds in the western part of Germany...
- Transcriptional analysis of in vitro expression patterns of Chlamydophila abortus polymorphic outer membrane proteins during the chlamydial developmental cycleNicholas Wheelhouse
Moredun Research Institute, Pentlands Science Park, Bush Loan, Edinburgh, Midlothian, EH26 0PZ, United Kingdom
Vet Res 40:47. 2009b>Chlamydophila abortus is the aetiological agent of ovine enzootic abortion. Sequencing, annotation and comparative analysis of the genome of C...
- Investigation of Chlamydiaceae in semen and cauda epididymidis and seroprevalence of Chlamydophila abortus in breeding bullsAnn Charlotte Karlsson
Division of Ruminant Medicine and Veterinary Epidemiology, Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences SLU, Box 7054, SE 750 07, Uppsala, Sweden
Acta Vet Scand 52:2. 2010..Reproductive disorders associated with chlamydial infection have been reported worldwide in cattle and there are indications of potential venereal transmission...
- An investigation into the role of Chlamydophila spp. in bovine upper respiratory tract diseaseD F Twomey
Veterinary Laboratories Agency, Staplake Mount, Starcross, Exeter, Devon EX6 8PE, UK
Vet J 171:574-6. 2006..Conjunctival swabs were collected and tested for Chlamydophila spp. DNA using a PCR test that detects Chlamydophila abortus and Chlamydophila psittaci...
- Detection of all Chlamydophila and Chlamydia spp. of veterinary interest using species-specific real-time PCR assaysAlexandra Pantchev
Chemisches und Veterinaruntersuchungsamt Stuttgart, Schaflandstr 3 3, 70736 Fellbach, Germany
Comp Immunol Microbiol Infect Dis 33:473-84. 2010..b>Chlamydophila (Cp.) abortus was the agent most frequently found in cattle, sheep, horses, goats, and pigs...
- Illuminating the evolutionary history of chlamydiaeMatthias Horn
Department of Microbial Ecology, Institute of Ecology and Conservation Biology, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
Science 304:728-30. 2004..Ancient chlamydiae appear to be the originators of mechanisms for the exploitation of eukaryotic cells...
- Protective adaptive immunity to Chlamydophila abortus infection and control of ovine enzootic abortion (OEA)Mara S Rocchi
Moredun Research Institute, Pentlands Science Park, Bush Loan, Midlothian, EH26 0PZ Scotland, UK
Vet Microbiol 135:112-21. 2009..The causative agent, Chlamydophila abortus, is a Gram-negative bacterium that can induce a persistent, subclinical infection in non-pregnant ..
- Monitoring clinical outcomes, pathological changes and shedding of Chlamydophila abortus following experimental challenge of periparturient ewes utilizing the natural route of infectionJorge Gutierrez
School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
Vet Microbiol 147:119-26. 2011Enzootic abortion of ewes (EAE) caused by Chlamydophila abortus is an important disease resulting in significant lamb loss in most sheep producing countries. Ewes are considered to be naturally infected with C...
- Comparison of fetal and maternal inflammatory responses in the ovine placenta after experimental infection with Chlamydophila abortusD J Sammin
Veterinary Research Laboratory, Department of Agriculture and Food, Staccumny Lane, Backweston, Celbridge, Co Kildare, Ireland
J Comp Pathol 135:83-92. 2006Placentae from 13 pregnant ewes infected intravenously with Chlamydophila abortus, together with placentae from nine uninfected control ewes, were examined at 14, 21 or 28 days post-inoculation (p.i.)...
- Identification of Chlamydophila abortus and the development of lesions in placental tissues of experimentally infected sheepS W Maley
Moredun Research Institute, Pentlands Science Park, International Research Centre, Bush Loan, Penicuik, Edinburgh EH26 0PZ, Scotland, United Kingdom
Vet Microbiol 135:122-7. 2009b>Chlamydophila (C.) abortus is a major cause of infectious abortion in sheep in many countries. Twenty-one pregnant sheep were experimentally infected intranasally with C. abortus at 70 days of gestation (dg)...
- Reinfection with Chlamydophila abortus by uterine and indirect cohort routes reduces fertility in cattle preexposed to ChlamydophilaFred J DeGraves
Department of Pathobiology, College of Veterinary Medicine, Auburn University, 264 Greene Hall, Auburn, Alabama 36849 5519, USA
Infect Immun 72:2538-45. 2004This study investigated the effects of controlled reinfection on fertility of cattle naturally preexposed to Chlamydophila abortus...
- Increased prevalence of Chlamydophila DNA in post-mortem brain frontal cortex from patients with schizophreniaBarbara Fellerhoff
Institute of Immunology, University of Munich, Goethestrasse 31, D 80336 Munich, Germany
Schizophr Res 129:191-5. 2011Infection can initiate symptoms of mental illness. It has been shown previously that Chlamydophila DNA is present six times more often in the blood of patients with schizophrenia than in the blood of control individuals...
- Genome sequence of the Chlamydophila abortus variant strain LLGMichelle Sait
Moredun Research Institute, Pentlands Science Park, Bush Loan, Edinburgh, Midlothian EH26 0PZ, United Kingdom
J Bacteriol 193:4276-7. 2011b>Chlamydophila abortus is a common cause of ruminant abortion. Here we report the genome sequence of strain LLG, which differs genotypically and phenotypically from the wild-type strain S26/3...
- Kinetics of infection and effects on the placenta of Chlamydophila abortus in experimentally infected pregnant ewesJ A Navarro
Departmento de Anatomía y Anatomía Patológica Comparadas, Facultad deVeterinaria, Universidad de Murcia, 30100 Murcia, Spain
Vet Pathol 41:498-505. 2004A Chlamydophila abortus-induced abortion model was carried out on the basis of the experimental infection of ewes at day 75 of gestation. The infection induced abortions and the birth of weak lambs during the last 3 weeks of pregnancy...
- Chlamydophila felis in cats--are the stray cats dangerous source of infection?M Halanova
Department of Public Health, Division of Epidemiology, Faculty of Medicine, P J Safarik University, Kosice, Slovak Republic
Zoonoses Public Health 58:519-22. 2011b>Chlamydophila felis is a causative agent of acute or chronic conjunctivitis, and pneumonia in cats. Natural transmission mostly occurs consequently to close contact with other infected cats, their aerosol and fomites...
- Chlamydophila felis CF0218 is a novel TMH family protein with potential as a diagnostic antigen for diagnosis of C. felis infectionKenji Ohya
Laboratory of Veterinary Microbiology, Faculty of Applied Biological Sciences, Gifu University, Yanagido 1 1, Gifu 501 1193, Japan
Clin Vaccine Immunol 15:1606-15. 2008b>Chlamydophila felis is a causative agent of acute and chronic conjunctivitis and pneumonia in cats (feline chlamydiosis). Also, C...
- The Chlamydophila felis plasmid is highly conservedRoss Harley
University of Bristol, School of Clinical Veterinary Science, Langford House, Langford, Bristol BS40 5DU, United Kingdom
Vet Microbiol 146:172-4. 2010..Although strains of Chlamydophila felis with or without the plasmid have been identified, only a small number of laboratory-adapted strains have ..
- Prevalence of antibodies against feline coronavirus and Chlamydophila felis in Swedish catsBodil Ström Holst
Department of Companion Animals and Horses, National Veterinary Institute, SE 751 89 Uppsala, Sweden
J Feline Med Surg 8:207-11. 2006..from 214 Swedish cats with no signs of infectious disease were analysed for the presence of antibodies against Chlamydophila felis (Cp felis), while 209 of these were also analysed for feline coronavirus (FCoV) antibodies...
- Therapeutic Chlamydophila abortus and C. pecorum vaccination transiently reduces bovine mastitis associated with Chlamydophila infectionCarolin Biesenkamp-Uhe
Bayer HealthCare AG, Osterather Strasse 1a, D 50739 Köln, Germany
Infect Immun 75:870-7. 2007Infections with Chlamydophila abortus and C. pecorum are highly prevalent in cattle and have been associated with bovine mastitis...
- Zoonotic potential of ChlamydophilaAnnie Rodolakis
INRA, UR1282 Infectiologie Animale et Santé Publique, F 37380 Nouzilly, France
Vet Microbiol 140:382-91. 2010..The purpose of this article is to present the diseases induced in humans and animals by the different species of Chlamydophila, after providing an overview on the history of these infectious agents and their taxonomy...
- [Humoral immune response in breeding sows after vaccination with a herd-specific Chlamydophila abortus vaccine]J C Knitz
Institut für Veterinärbakteriologie, Universitat Zurich, Schweiz
Dtsch Tierarztl Wochenschr 110:369-74. 2003..in sterile 0.15 M saline was prepared from Chlamydophila (Ch.) abortus strain OCHL03/99 which has been isolated in the herd from a sample of vaginal discharge...
- Recent developments in the laboratory diagnosis of chlamydial infectionsKonrad Sachse
Friedrich Loeffler Institut Federal Research Institute for Animal Health, Institute of Molecular Pathogenesis, Naumburger Str 96a, 07743 Jena, Germany
Vet Microbiol 135:2-21. 2009There are two main approaches to diagnosing infections by Chlamydia and Chlamydophila spp. in mammals and birds...
- High prevalence of natural Chlamydophila species infection in calvesJunBae Jee
Department of Pathobiology, College of Veterinary Medicine, Auburn University, 270 Greene Hall, Auburn, AL 36849 5519, USA
J Clin Microbiol 42:5664-72. 2004We investigated the acquisition and prevalence of Chlamydophila sp. infection in calves. Specimens were collected at weekly intervals from birth to week 12 postpartum from 40 female Holstein calf-dam pairs in a dairy herd...
- BLAST screening of chlamydial genomes to identify signature proteins that are unique for the Chlamydiales, Chlamydiaceae, Chlamydophila and Chlamydia groups of speciesEmma Griffiths
Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, L8N 3Z5, Canada
BMC Genomics 7:14. 2006..The obligate intracellular nature of chlamydiae has also limited their genetic and biochemical studies. Thus, it is of importance to develop additional means for their identification and characterization...
- Prevalence of antibodies against Chlamydophila abortus and Coxiella burnetii in goat herds in PolandM Czopowicz
Division of Infectious Diseases and Veterinary Epidemiology, Department of Clinical Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 159C, 02 776 Warsaw, Poland
Pol J Vet Sci 13:175-9. 2010An epidemiological study was carried out to determine the herd prevalence of Chlamydophila abortus and Coxiella burnetii antibodies in goats covered by a milk recording program in Poland...
- Isolation, molecular characterisation and genome sequence of a bacteriophage (Chp3) from Chlamydophila pecorumSarah A Garner
Molecular Microbiology and Infection, University Medical School, Southampton General Hospital, Southampton SO16 6YD, UK
Virus Genes 28:207-14. 2004..Comparative analyses demonstrate that the chlamydiaphages can be further subdivided into two groupings, one represented by Chp2/Chp3 and the other by ØCPG1/ØCPAR39...
- Tissue MicroArray (TMA) analysis of normal and persistent Chlamydophila pneumoniae infectionNicole Borel
Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
BMC Infect Dis 6:152. 2006b>Chlamydophila pneumoniae infection has been implicated as a potential risk factor for atherosclerosis, however the mechanism leading to persistent infection and its role in the disease process remains to be elucidated.
- Evidence of Chlamydophila abortus vaccine strain 1B as a possible cause of ovine enzootic abortionNicholas Wheelhouse
Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian EH26 0PZ, UK
Vaccine 28:5657-63. 2010b>Chlamydophila abortus, the agent of ovine enzootic abortion (OEA), is a major cause of lamb mortality worldwide. Disease can be controlled through the use of vaccines based on the 1B temperature-sensitive mutant strain of C. abortus...
- Predator or prey? Chlamydophila abortus infections of a free-living amoebae, Acanthamoeba castellani 9GUMirjam Wirz
Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 268, CH 8057 Zurich, Switzerland
Microbes Infect 10:591-7. 2008..PCR and microscopic analyses of Chlamydophila abortus infections of Acanthamoeba castellani revealed uptake of this chlamydial pathogen but, unlike the well-..
- Previous infection with the nematode Nippostrongylus brasiliensis alters the immune specific response against Chlamydophila abortus infectionAntonio Buendía
Departamento de Histologia y Anatomia Patologica, Universidad de Murcia, Campus de Espinardo, 30100, Murcia, Spain
Microb Pathog 33:7-15. 2002..interaction between the immune responses elicited following infection with Nippostrongylus brasiliensis and Chlamydophila abortus has been established. Mice infected with C. abortus 7 days after N...
- Abortive potency of Chlamydophila abortus in pregnant mice is not directly correlated with placental and fetal colonization levelsAmel Bouakane
Unité de Recherche Pathologie Infectieuse et Immunologie, Institut National de la Recherche Agronomique, Centre de Tours Nouzilly, 37380 Nouzilly, France
Infect Immun 71:7219-22. 2003Abortion, placental and fetal colonization, and levels of gamma interferon were analyzed for four Chlamydophila abortus strains presenting antigenic variations in a mouse model...
- Simultaneous differential detection of Chlamydophila abortus, Chlamydophila pecorum and Coxiella burnetii from aborted ruminant's clinical samples using multiplex PCRMustapha Berri
Institut National de la Recherche Agronomique INRA, UR1282, Infectiologie Animale et Santé Publique IASP, F 37380 Nouzilly, France
BMC Microbiol 9:130. 2009..They are caused respectively by strictly intracellular and Gram negative bacterium Chlamydophila abortus (Cp. abortus) and Coxiella burnetii (C. burnetii). Chlamydophila pecorum (Cp...
- Identification, sequencing and molecular analysis of Chp4, a novel chlamydiaphage of Chlamydophila abortus belonging to the family MicroviridaeMichelle Sait
Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian EH26 0PZ, UK
J Gen Virol 92:1733-7. 2011..family Microviridae have been identified in a number of chlamydial species infecting humans (phage CPAR39 in Chlamydophila pneumoniae), other mammals (φCPG1 in Chlamydophila caviae, Chp2 in Chlamydophila abortus and Chp3 in ..
- An etiological investigation of domestic cats with conjunctivitis and upper respiratory tract disease in JapanYan Cai
Department of Veterinary Microbiology, Faculty of Agriculture, Gifu University, Japan
J Vet Med Sci 64:215-9. 2002b>Chlamydophila felis (C. felis), feline herpesvirus-1 (FHV-1) and feline calicivirus (FCV) were detected in 39 (59.1%), 11 (16.7%) and 14 (21...
- Molecular cloning of the Chlamydophila abortus groEL gene and evaluation of its protective efficacy in a murine model by genetic vaccinationCéline Héchard
Unite de Pathologie Infectieuse et Immunologie, INRA Centre de Tours, 37380 Nouzilly, France
J Med Microbiol 53:861-8. 2004The immunogenicity and protective effect of a DNA vaccine encoding the heat-shock protein (Hsp) GroEL of Chlamydophila abortus AB7, an obligate intracellular bacterium that causes abortion in sheep, was evaluated in pregnant and non-..
- Hematology, plasma chemistry, serology, and Chlamydophila status of the waved albatross (Phoebastria irrorata) on the Galapagos IslandsLuis R Padilla
Saint Louis Zoological Park, 1 Government Drive, St Louis, Missouri 63110, USA
J Zoo Wildl Med 34:278-83. 2003..Of 44 birds, 29 (66%) seroreacted to adenovirus group 1, and four seroreacted to avian encephalomyelitis. Cloacal swabs were negative for Chlamydophila psittaci DNA.
- Differential identification of Chlamydophila abortus live vaccine strain 1B and C. abortus field isolates by PCR-RFLPKarine Laroucau
Unité Zoonoses Bactériennes, Agence Française de Sécurité Sanitaire des Aliments Lerpaz, 23 Avenue du Général de Gaulle, 94706 Maisons Alfort cedex, France
Vaccine 28:5653-6. 2010Comparative genomic analysis of a wild-type strain of the ovine pathogen Chlamydophila abortus and its nitrosoguanidine-induced, temperature-sensitive and virulence-attenuated live vaccine derivative identified point mutations unique to ..
- Factors associated with upper respiratory tract disease caused by feline herpesvirus, feline calicivirus, Chlamydophila felis and Bordetella bronchiseptica in cats: experience from 218 European catteriesC R Helps
University of Bristol, Bristol BS40 5DU
Vet Rec 156:669-73. 2005..The prevalences of feline herpesvirus (FHV), feline calicivirus (FCV), Chlamydophila felis and Bordetella bronchiseptica were determined by PCR on swab samples...
- Comparative evaluation of eight serological assays for diagnosing Chlamydophila abortus infection in sheepKim Wilson
Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik EH26 OPZ, UK
Vet Microbiol 135:38-45. 2009b>Chlamydophila abortus is one of the principal causes of late-term abortion (enzootic abortion of ewes or EAE) in sheep across Europe...
- Prevalence of Chlamydophila felis and feline herpesvirus 1 in cats with conjunctivitis in northern ItalyA Rampazzo
College of Veterinary Medicine, University of Torino, 10095 Grugliasco, Italy
J Vet Intern Med 17:799-807. 2003The prevalence of Chlamydophila felis and feline herpesvirus 1 (FHV-1) infection in cats with conjunctivitis in northern Italy was investigated by conventional polymerase chain reaction (PCR) testing...
- Recent advances in the understanding of Chlamydophila pecorum infections, sixteen years after it was named as the fourth species of the Chlamydiaceae familyKhalil Yousef Mohamad
Institut National de la Recherche Agronomique INRA, UR1282, Infectiologie Animale et Sante Publique, F 37380 Nouzilly Tours, France
Vet Res 41:27. 2010b>Chlamydophila pecorum found in the intestine and vaginal mucus of asymptomatic ruminants has also been associated with different pathological conditions in ruminants, swine and koalas...
- Subspecies variation in Greek strains of Chlamydophila abortusVictoria Siarkou
Laboratory of Microbiology and Infectious Diseases, Faculty of Veterinary Medicine, Aristotle University, 540 06, Thessaloniki, Greece
Vet Microbiol 85:145-57. 2002..Using the restriction enzymes BfaI, SfcI, HpaI, BclI, DdeI and AclI, the strains were classified as Chlamydophila abortus...
- Toxoplasma gondii and Chlamydophila abortus in caprine abortions in Tobago: a sero-epidemiological studyG Borde
Faculty of Medical Sciences, School of Veterinary Medicine, University of the West Indies, St Augustine, Trinidad and Tobago
J Vet Med B Infect Dis Vet Public Health 53:188-93. 2006..The sera were screened for Toxoplasma gondii antibodies using the latex agglutination test (LAT), Chlamydophila abortus with an enzyme-linked immunosorbent assay (ELISA) and Brucella abortus using the buffered plate ..
- Field evaluation of a new commercially available ELISA based on a recombinant antigen for diagnosing Chlamydophila abortus (Chlamydia psittaci serotype 1) infectionA J Buendia
Departamento de Patología Animal Microbiología e Inmunología, Facultad de Veterinaria, Universidad de Murcia, Campus de Espinardo, 30100, Murcia, Spain
Vet Microbiol 78:229-39. 2001A new commercially available ELISA (ELISAr-Chlamydia) for detecting antibodies against Chlamydophila abortus has been evaluated using sheep field serum samples...
- Vaccination against chlamydial infections of man and animalsD Longbottom
Moredun Research Institute, Pentlands Science Park, International Research Center, Bush Loan, Penicuik, Midlothian, Edinburgh EH26 0PZ, UK
Vet J 171:263-75. 2006..has been in developing whole organism based killed or live attenuated vaccines against the animal pathogens Chlamydophila abortus and Chlamydophila felis...
- Identification and characterisation of coding tandem repeat variants in incA gene of Chlamydophila pecorumKhalil Yousef Mohamad
INRA, UR1282, Infectiologie Animale et Sante Publique, Centre de Recherche de Tours, F 37380 Nouzilly, France
Vet Res 39:56. 2008Bacteria of the family Chlamydiaceae are obligate intracellular pathogens of human and animals. Chlamydophila pecorum is associated with different pathological conditions in ruminants, swine and koala...
- Protection of pregnant mice against placental and splenic infection by three strains of Chlamydophila abortus with a live 1B vaccineA Bouakane
Unite de Pathologie Infectieuse et Immunologie, INRA Centre de Tours, 37380 Nouzilly, France
Vet Rec 157:771-4. 2005The efficacy of a live 1B vaccine against three strains of Chlamydophila abortus, AB16, LLG and POS, was assessed in pregnant mice in terms of the reduction in the levels of infection recorded in their placentas, fetuses and spleens...
- Identification and characterization of Inc766, an inclusion membrane protein in Chlamydophila abortus-infected cellsEvangelia Vretou
Laboratory of Biotechnology, Department of Microbiology, Hellenic Pasteur Institute, 127 Vassilissis Sofias Avenue, 11521 Athens, Greece
Microb Pathog 45:265-72. 2008We have identified the gene product of locus 766 in the transmembrane head region (TMH/Inc-region) in the Chlamydophila abortus genome by using mass spectrometry and a monoclonal antibody that reacted with the inclusion membrane...
- Induction of a protective immune response against swine Chlamydophila abortus infection in mice following co-vaccination of omp-1 DNA with recombinant MOMPF Zhang
Key Lab of Preventive Veterinary Medicine of Chinese Ministry of Agriculture, China Agricultural University, Beijing, China
Zoonoses Public Health 56:71-6. 2009b>Chlamydophila abortus is the causative agent of abortion in pigs and pregnant women. Seroconversion rates were arranged from 11% to 80% in piglets and sows in China...
- Biological properties and cell tropism of Chp2, a bacteriophage of the obligate intracellular bacterium Chlamydophila abortusJ S Everson
Molecular Microbiology and Infection, University Medical School, Southampton General Hospital, Southampton SO16 6YD, United Kingdom
J Bacteriol 184:2748-54. 2002..Phylogenetic studies divide the Chlamydiaceae into two distinct genera, Chlamydia and Chlamydophila, containing three and six different species, respectively...
- Host alpha-adducin is redistributed and localized to the inclusion membrane in chlamydia- and chlamydophila-infected cellsHencelyn G Chu
Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, OR 97331 4804, USA
Microbiology 154:3848-55. 2008..trachomatis- and Chlamydophila caviae-infected cells, but the total cellular protein abundance remained unaffected by infection...
- Induction of inflammatory host immune responses by organisms belonging to the genera Chlamydia/ChlamydophilaGary Entrican
Moredun Research Institute, Pentlands Science Park, Bush Loan, Edinburgh EH26 0PZ, UK
Vet Immunol Immunopathol 100:179-86. 2004Chlamydia/Chlamydophila are a family of intracellular gram-negative bacteria that infect their hosts primarily via mucosal epithelia...
- OmpA and antigenic diversity of bovine Chlamydophila pecorum strainsB Kaltenboeck
Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA
Vet Microbiol 135:175-80. 2009Infections with the intracellular bacterium Chlamydophila (C.) pecorum are highly prevalent worldwide in cattle...
- Diagnosis of ovine enzootic abortion using an indirect ELISA (rOMP91B iELISA) based on a recombinant protein fragment of the polymorphic outer membrane protein POMP91B of Chlamydophila abortusD Longbottom
Moredun Research Institute, International Research Centre, Pentlands Science Park, Penicuik, Midlothian, UK
FEMS Microbiol Lett 195:157-61. 2001b>Chlamydophila abortus is of major economic importance worldwide as one of the principal causes of abortion in sheep...
- Improved sensitivity of PCR for Chlamydophila using pmp genesK Laroucau
, INRA-Centre de Tours, 37380 Nouzilly, France
Vet Microbiol 82:155-64. 2001Primers targeting the conserved pmp gene family of Chlamydophila abortus were evaluated for their ability to improve the polymerase chain reaction (PCR) sensitivity...
- Antibody responses to recombinant protein fragments of the major outer membrane protein and polymorphic outer membrane protein POMP90 in Chlamydophila abortus-infected pregnant sheepMorag Livingstone
Moredun Research Institute, International Research Centre, Pentlands Science Park, Penicuik EH26 0PZ, United Kingdom
Clin Diagn Lab Immunol 12:770-7. 2005b>Chlamydophila abortus is one of the major causes of infectious abortion in pregnant sheep (enzootic abortion of ewes or EAE) worldwide...
- Prevalence of Chlamydophila abortus infection in domesticated ruminants in TaiwanF I Wang
Department of Veterinary Medicine, National Taiwan University, Taipei
J Vet Med Sci 63:1215-20. 2001This study is to (1) investigate the prevalence of Chlamydophila abortus infection in cows and goats in Taiwan, and (2) compare the genetic properties of Taiwanese isolates with abortion strains from other sources...
- Epizootic abortion related to infections by Chlamydophila abortus and Chlamydophila pecorum in water buffalo (Bubalus bubalis)G Greco
Department of Animal Health and Wellbeing, Faculty of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy
Theriogenology 69:1061-9. 2008..By a nested-PCR assay, three of 14 vaginal swabs from aborted animals tested positive for Chlamydophila agents and, additionally, three out of seven aborted fetuses tested positive for Chlamydophila spp...
- Experimental infection of pregnant ewes with enteric and abortion-source Chlamydophila abortusP Tsakos
Laboratory of Microbiology and Infectious Diseases, Faculty of Veterinary Medicine, Aristotle University, 54 006, Thessaloniki, Greece
Vet Microbiol 82:285-91. 2001..A faecal and an abortion-source isolate of Chlamydophila abortus were used...
- Ovine enzootic abortion (OEA): antibody response in vaccinated sheep compared to naturally infected sheepN Borel
I Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 268, CH 8057 Zurich, Switzerland
Vet Res Commun 29:151-6. 2005
- Comparison of ELISA and CFT assays for Chlamydophila abortus antibodies in ovine seraL M E McCauley
Primary Industries Research Victoria, Department of Primary Industries, Attwood, VIC 3049, Australia
Aust Vet J 85:325-8. 2007To compare the sensitivity and specificity of Chlamydophila abortus antibody assays, to find a suitable serological assay for testing sheep for export.
- A clinically silent respiratory infection with Chlamydophila spp. in calves is associated with airway obstruction and pulmonary inflammationJulia Jaeger
Institute of Molecular Pathogenesis in the Friedrich Loeffler Institute Federal Research Institute for Animal Health, Naumburger Str 96a, 07743 Jena, Germany
Vet Res 38:711-28. 2007..Thirteen calves persistently infected with Chlamydophila (C.) abortus and/or C. pecorum (Chl+) were compared to 12 calves without chlamydial infections (Chl-)...
- Use of real-time quantitative PCR to detect Chlamydophila felis infectionC Helps
Division of Molecular and Cellular Biology, Department of Clinical Veterinary Science, University of Bristol, Langford, Bristol, BS40 5DU, United Kingdom
J Clin Microbiol 39:2675-6. 2001A real-time PCR assay was developed to detect and quantify Chlamydophila felis infection of cats...
- Evaluation of two commercial assays for the detection of Chlamydophila abortus antibodiesE Vretou
Department of Microbiology, Hellenic Pasteur Institute, 127 Avenue Vassilissis Sofias, 115 21 Athens, Greece
Vet Microbiol 123:153-61. 2007Two commercial enzyme-linked immunosorbent assays (ELISA), the CHEKIT-CHLAMYDIA which uses inactivated Chlamydophila psittaci antigen, and the Chlamydophila abortus ELISA produced by the Institut Pourquier which uses a recombinant ..
- Chlamydophila abortus-induced keratoconjunctivitis in a dogK Hoelzle
Institute of Veterinary Bacteriology, University of Zurich, Winterthurerstrasse 270, 8057 Zurich, Switzerland
Vet Rec 157:632-3. 2005
- The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variationNicholas R Thomson
The Pathogen Sequencing Unit, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
Genome Res 15:629-40. 2005The obligate intracellular bacterial pathogen Chlamydophila abortus strain S26/3 (formerly the abortion subtype of Chlamydia psittaci) is an important cause of late gestation abortions in ruminants and pigs...
- Chlamydophila abortus infection in a pregnant woman associated with indirect contact with infected goatsA Meijer
Diagnostic Laboratory for Infectious Diseases and Perinatal Screening, National Institute of Public Health and the Environment, P O Box 1, 3720 BA Bilthoven, The Netherlands
Eur J Clin Microbiol Infect Dis 23:487-90. 2004Reported here is the case of a pregnant woman who developed a severe Chlamydophila abortus infection after indirect contact with infected goats resulting in preterm stillbirth. The woman fully recovered after treatment with doxycycline...
- Host range of chlamydiaphages phiCPAR39 and Chp3J S Everson
Molecular Microbiology and Infection, University Medical School, Southampton General Hospital, Southampton, SO16 6YD, United Kingdom
J Bacteriol 185:6490-2. 2003The host range of phiCPAR39 is limited to four Chlamydophila species: C. abortus, C. caviae, C. pecorum, and C. pneumoniae. Chp3 (a newly discovered bacteriophage isolated from C. pecorum) shares three of these hosts (C. abortus, C...
- Avian host range of Chlamydophila spp. based on isolation, antigen detection and serologyE F Kaleta
Klinik fur Vogel, Reptilien, Amphibien und Fische, Fachbereich Veterinarmedizin, Justus Liebig Universitat Giessen, Frankfurter Strasse 91 93, D 35392 Giessen, Germany
Avian Pathol 32:435-61. 2003Published reports and our own diagnostic data on the avian host range of avian Chlamydophila spp. are presented in an attempt to provide evidence for the large number of bird species that have been naturally infected with chlamydia...
- Antigenic organization of the N-terminal part of the polymorphic outer membrane proteins 90, 91A, and 91B of Chlamydophila abortusEvangelia Vretou
Laboratory of Biotechnology, Department of Microbiology, Hellenic Pasteur Institute, Athens 115 21, Greece
Infect Immun 71:3240-50. 2003..antigens, 61 to 74 residues in length, representing polymorphic outer membrane protein 90 (POMP90) of Chlamydophila abortus and two recombinant peptides spanning gene fragment p91Bf99 of POMP91B were assessed by immunoblotting ..
- Comparison of polymerase chain reaction and cell culture for the detection of Chlamydophila species in the semen of bulls, buffalo-bulls, and ramsAdel S Amin
Animal Reproduction Research Institute ARRI, Giza, Egypt
Vet J 166:86-92. 2003..collected from 120 bulls, 60 buffalo-bulls, and 56 rams located on farms of known history of infection with Chlamydophila species...
- Detection of Chlamydophila felis and feline herpesvirus by multiplex real-time PCR analysisChris Helps
Division of Molecular and Cellular Biology, Department of Clinical Veterinary Science, University of Bristol, Langford, Bristol BS40 5DU, United Kingdom
J Clin Microbiol 41:2734-6. 2003b>Chlamydophila felis and feline herpesvirus (FHV) are pathogens commonly associated with feline respiratory and ocular disease...
- Missing links in the divergence of Chlamydophila abortus from Chlamydophila psittaciM Van Loock
Department of Animal Sciences, Katholieke Universiteit Leuven, Kasteelpark Arenberg 21 Laboratory of Gene Technology, 3001 Leuven, Belgium
Int J Syst Evol Microbiol 53:761-70. 2003Pathological and serological evidence and DNA-DNA reassociation data indicate that Chlamydophila psittaci and Chlamydophila abortus are separate species. C. psittaci causes avian systemic disease and C. abortus causes abortion...
- Chlamydial development is blocked in host cells transfected with Chlamydophila caviae incADamir Alzhanov
Department of Microbiology, Oregon State University, Corvallis, OR 97331 3804 USA
BMC Microbiol 4:24. 2004..Little information exists regarding the interaction of Inc proteins with the eukaryotic cell. To examine these interactions, Vaccinia virus vectors and mammalian plasmid-based systems were used to express inc genes in mammalian cells...
- Suspected chlamydial keratoconjunctivitis in British cattleA Otter
Vet Rec 152:787-8. 2003
- Efficacy of live Chlamydophila abortus vaccine 1B in protecting mice placentas and foetuses against strains of Chlamydophila pecorum isolated from cases of abortionA Rekiki
Unite de Pathologie Infectieuse et Immunologie, INRA Centre de Tours, 37380 Nouzilly, France
Vet Microbiol 99:295-9. 2004The efficacy of Chlamydophila abortus vaccine strain 1B in protecting against two selected Chlamydophila pecorum strains, isolated from an aborted goat (M14) in Morocco and a ewe (AB10) in France, was investigated in a mouse model, by ..
- Molecular detection of Chlamydophila abortus in post-abortion sheep at oestrus and subsequent lambingMorag Livingstone
Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian EH26 OPZ, UK
Vet Microbiol 135:134-41. 2009Enzootic abortion of ewes (EAE), resulting from infection with the bacterium Chlamydophila abortus (C. abortus), is a major cause of lamb loss in Europe...
- Preliminary phylogenetic identification of virulent Chlamydophila pecorum strainsKhalil Yousef Mohamad
INRA, UR1282 Infectiologie Animale et Santé Publique, F 37380 Nouzilly, France
Infect Genet Evol 8:764-71. 2008b>Chlamydophila pecorum is an obligate intracellular bacterium associated with different pathological conditions in ruminants, swine and koala, which is also found in the intestine of asymptomatic animals...
- Expression of the major outer membrane protein (MOMP) of Chlamydophila abortus, Chlamydophila pecorum, and Chlamydia suis in Escherichia coli using an arabinose-inducible plasmid vectorL E Hoelzle
Institute of Veterinary Bacteriology, University of Zurich, Winterthurerstrasse 270, CH 8057 Zurich, Switzerland
J Vet Med B Infect Dis Vet Public Health 50:383-9. 2003The ompA genes encoding the 40 kDa major outer membrane protein (MOMP) of Chlamydophila (Ch.) abortus, Ch. pecorum, and Chlamydia (C...
- DNA microarray-based detection and identification of Chlamydia and Chlamydophila sppKonrad Sachse
Institute of Bacterial Infections and Zoonoses at the Federal Research Institute for Animal Health Friedrich Loeffler Institut, Naumburger Str 96a, 07743 Jena, Germany
Mol Cell Probes 19:41-50. 2005..The present assay proved suitable for unambiguous species identification of chlamydial cell cultures and showed a potential for direct detection of these bacteria from clinical tissue...
- A new family of highly variable proteins in the Chlamydophila pneumoniae genomeEduardo P C Rocha
Unité GGB, CNRS URA2171, Institut Pasteur, Paris, France
Nucleic Acids Res 30:4351-60. 2002..We find a larger potential for recombination in Chlamydophila pneumoniae genomes as compared with Chlamydia trachomatis or Chlamydia muridarum...
- Genotyping of Chlamydophila abortus strains by multilocus VNTR analysisKarine Laroucau
Unité Zoonoses Bactériennes, Agence Française de Sécurité Sanitaire des Aliments Lerpaz, 94706 Maisons Alfort cedex, France
Vet Microbiol 137:335-44. 2009b>Chlamydophila (C.) abortus is the causative agent of ovine enzootic abortion with zoonotic potential whose epidemiology has been held back because of the obligate intracellular habitat of the bacterium...
- Investigation of Chlamydophila spp. in dairy cows with reproductive disordersAnn Charlotte Godin
Division of Ruminant Medicine and Veterinary Epidemiology, Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences SLU, SE 750 07, Uppsala, Sweden
Acta Vet Scand 50:39. 2008Reports worldwide indicate high prevalence of Chlamydophila spp. infection in cattle. To assess the prevalence in Sweden, 525 cows in 70 dairy herds with reproductive disorders was investigated.
- Suspected chlamydial polyarthritis in a calf in the UKD F Twomey
Vet Rec 152:340. 2003
- Efficacy of different commercial and new inactivated vaccines against ovine enzootic abortionJ N García de la Fuente
Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de Leon, Unidad de Microbiologia e Inmunologia, Campus de Vegazana, S N, 24007 Leon, Spain
Vet Microbiol 100:65-76. 2004..For the preparation of the experimental vaccines, Chlamydophila abortus AB7 strain was cultured in McCoy cells and adjuvated with QS-21 (QS) or Montanide ISA 773 (M7)...
- CpG motifs as adjuvant in DNA vaccination against Chlamydophila psittaci in turkeysKarolien Loots
Laboratory of Physiology and Immunology of Domestic Animals, Faculty of Applied Bioscience and Engineering, K U Leuven, Kasteelpark Arenberg 30, B 3001 Leuven, Belgium
Vaccine 24:4598-601. 2006Plasmid DNA (pcDNA1::MOMP) expressing the major outer membrane protein (MOMP) of an avian Chlamydophila psittaci serovar D strain and recombinant MOMP (rMOMP) with or without the immunomodulating CpG oligonucleotides (CpG ON) were tested ..
- Validation of an internal method for the diagnosis of infections with Chlamydophila abortus and Coxiella burnetii by real-time multiplex PCRC Pelletier
Laboratoire Départemental d Analyses de Saône et Loire, Macon, France
Dev Biol (Basel) 126:219-26; discussion 326-7. 2006b>Chlamydophila abortus and Coxiella burnetii are one of the major pathogens implicated in abortion in cattle...
- Characterization of a murine model of intranasal infection suitable for testing vaccines against C. abortusA J Buendia
Departamento de Histologia y Anatomia Patologica, Facultad de Veterinaria, Universidad de Murcia, Campus de Espinard, 30100 Murcia, Spain
Vet Immunol Immunopathol 115:76-86. 2007Mouse models have been widely used to test candidate vaccines against Chlamydophila abortus infection in mice...
- Epidemiological and pathological study on the causes of abortion in sheep and goats in Hungary (1998-2005)L Szeredi
Central Veterinary Institute, H 1149 Budapest, Tábornok u 2, Hungary
Acta Vet Hung 54:503-15. 2006..The most important cause of ovine and caprine abortions was Chlamydophila abortus infection with a prevalence of 46% and 17%, respectively...
- Prevalence of feline herpesvirus 1, Chlamydophila felis, and Mycoplasma spp DNA in conjunctival cells collected from cats with and without conjunctivitisHeather C Low
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
Am J Vet Res 68:643-8. 2007To use PCR assays to determine the prevalence of feline herpesvirus 1 (FHV-1), Chlamydophila felis, and Mycoplasma spp DNA in conjunctival cells collected from cats with and without conjunctivitis; to compare results of conventional and ..
- Evaluation of Chlamydophila abortus DNA extraction protocols for polymerase chain reaction diagnosis in paraffin-embedded tissuesNieves Ortega
Departmento de Sanidad Animal, Facultad de Veterinaria, Universidad de Murcia, Murcia, Spain
J Vet Diagn Invest 19:421-5. 2007..chain reaction (PCR) has gained increasing importance as a tool for directly demonstrating the presence of Chlamydophila in the placentas of aborted sheep and goats...
- Detection of the genome of Chlamydophila abortus in samples taken from the uteri of 304 sheep at an abattoirE Michalopoulou
Department of Veterinary Pathology, University of Liverpool, Leahurst, Neston, South Wirral CH64 7TE
Vet Rec 161:153-5. 2007A PCR was used to detect the genome of Chlamydophila abortus in samples of uterine tissue collected from 304 sheep by a sterile technique at an abattoir...
- Etiological investigation of multiple respiratory infections in catsB Di Martino
Department of Comparative Biomedical Sciences, University of Teramo, Italy
New Microbiol 30:455-61. 2007..one hundred animals with clinical signs were investigated for detection of Feline Herpesvirus type-1 (FHV-1), Chlamydophila felis, Feline Calicivirus (FCV) and Bordetella bronchiseptica from mucosal swabs...
- Prevalence and epidemiological features of ovine enzootic abortion in LithuaniaJ Bagdonas
Department of Infectious Diseases, Lithuanian Veterinary Academy, Tilzes 18, LT 47181 Kaunas, Lithuania
Pol J Vet Sci 10:239-44. 2007..Analysis of smears from patological material by indirect FAT revealed that 54.5% of animals were positive to Chlamydophila abortus infection. The highest prevalence of chlamydia (66...
- Occurrence of antibodies against Chlamydophila abortus in sheep and goats in the Slovak RepublicLydia Cislakova
Department of Epidemiology, Faculty of Medicine, P J Safarik University, Srobarova 2, 041 80 Kosice, Slovak Republic
Ann Agric Environ Med 14:243-5. 2007b>Chlamydophila abortus is one of the most important causative agents of enzootic abortion and other chlamydial infections of sheep and goats...
- Molecular characterisation of 12 Chlamydophila felis polymorphic membrane protein genesRoss Harley
School of Clinical Veterinary Science, University of Bristol, Langford House, Langford, Bristol BS40 5DU, United Kingdom
Vet Microbiol 124:230-8. 2007..members of the unique chlamydial polymorphic membrane protein (pmp) family were recently described in the Chlamydophila felis genome...
- Investigation of pre-natal Chlamydophila abortus (Chlamydia psittaci) exposure of female lambs and the outcome of their first pregnancyH L Philips
Department of Veterinary Clinical Science and Animal Husbandry, Faculty of Veterinary Science, University of Liverpool Teaching Hospital, Leahurst, Neston CH64 7TE, UK
Vet J 163:329-30. 2002
- Evaluation of an automated complement fixation test (Seramat) for the detection of chlamydial antibodies in sheep and goat seraS Magnino
Istituto Zooprofilattico Sperimentale della Lombardia e dell Emilia Romagna Bruno Ubertini, National Reference Laboratory for Animal Chlamydioses, Via Taramelli 7, 27100 Pavia, Italy
Vet Res Commun 29:157-61. 2005
- Diagnosis of ovine chlamydial abortions by PCR-RFLP performed on vaginal swabsF Marsilio
Dipartimento di Scienze Biomediche Comparate, Faculty of Veterinary Medicine, University of Teramo, Italy
Vet Res Commun 29:99-106. 2005..The etiological agent is Chlamydophila (C...
- Respiratory Panel Flow-Strip: a Point-of-Care Molecular Diagnostic TestCHRISTOPHER GERARD COONEY; Fiscal Year: 2012..human parainfluenza virus 1/2/3/4, Haemophilus influenzae, Streptococcus pneumoniae, Mycoplasma pneumoniae, Chlamydophila pneumoniae, Legionella pneumophila, and Bordetella pertussis...
- Role of Innate Immune System in Pathogen Induced Chronic InflammationCaroline A Genco; Fiscal Year: 2013..The pathogenic bacteria Chlamydophila pneumoniae and Porphyromanas gingivalis induce a chronic inflammatory response, although how these pathogens ..
- Nanotechnology-Based Detection of Mycoplasma pneumoniaeDuncan C Krause; Fiscal Year: 2013..assess NA- SERS discriminatory ability in mixed infections with other bacterial pathogens including Chlamydophila pneumoniae;and (2) test by NA-SERS, true clinical throat swab samples previously established as positive or ..
- CHLAMYDIAL INVASION OF NON-PHAGOCYTIC CELLSREYNALDO CARABEO; Fiscal Year: 2009..Specific Aim 3 will address the potential mechanism of actin recruitment by the Chlamydophila caviae Tarp homolog, which does not contain the multiple repeat sequences present in C...
- Chlamydia pneumoniae vaccine candidatesBernhard Kaltenboeck; Fiscal Year: 2004..pneumoniae vaccine candidate proteins in respiratory disease models using several inbred mouse strains. ..
- Gene Duplication and Genome EvolutionAustin Hughes; Fiscal Year: 2004..5) Examining the role of transposable elements in duplication of genomic segments by testing for nonrandom association between these elements and putatively duplicated blocks in the yeast genome. ..
- CHLAMYDIA PNEUMONIAE--A PATHOGEN IN ALZHEIMERS DISEASEAlan Hudson; Fiscal Year: 2002..Such new information may well provide important new insights for development of novel therapeutic modalities to prevent or ameliorate late-onset AD. ..
- Obesity, Inflammation and Response to Therapy in AsthmaEVERETT RAND SUTHERLAND; Fiscal Year: 2010..End of Abstract) ..
- EVOLUTION OF IMMUNE RECOGNITION AND EVASIONAustin L Hughes; Fiscal Year: 2010..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
- Innate Immunity and RSV Infection in ChildrenTheresa Guilbert; Fiscal Year: 2007..Accomplishment of these aims will allow us to begin to elucidate the immune mechanisms of the major gene-environment interactions influencing early childhood respiratory disease. ..
- Reiter's syndrome mechanism of chlamydial pathogenesisAlan Hudson; Fiscal Year: 2008....
- C. trachomatis genomics, strain typing, and evolutionDeborah Dean; Fiscal Year: 2008..unreadable] [unreadable]..
- PATHOGENESIS OF CHLAMYDIAL OCULAR INFECTIONSDeborah Dean; Fiscal Year: 2004..A greater understanding of the pathogenesis of trachoma will aid in developing public health interventions and a vaccine that can be implemented in trachoma endemic areas throughout the world. ..
- Functional Genomic Analysis of the Chlamydia InclusionRAPHAEL VALDIVIA; Fiscal Year: 2005..We expect that the functional approach we propose will lead to the identification of novel classes of virulence factors and represent a major breakthrough in our understanding of Chlamydia pathogenesis. ..
- Chlamydia co-option of Eukaryotic Lipid DropletsRaphael H Valdivia; Fiscal Year: 2010..abstract_text> ..
- Atypical Bacterial Infection as an Asthma Risk FactorEVERETT SUTHERLAND; Fiscal Year: 2005..The candidate is intent upon using this award to support a career development program that will ensure his success as an academic physician-scientist with a focus on patient-oriented research in diseases of the lungs...
- Pathogenesis of Persistent Chlamydial STDsDeborah Dean; Fiscal Year: 2007..1 Description, ..
- Asthma: Insights & Expectations. 51st Annual Thomas L Petty Aspen Lung ConferenceEVERETT SUTHERLAND; Fiscal Year: 2008..unreadable] DESCRIPTION (provided by applicant): [unreadable] [unreadable] N/A [unreadable] [unreadable] [unreadable]..
- Identification of Coxiella burnetti Effector ProteinsRAPHAEL VALDIVIA; Fiscal Year: 2008..We predict that these factors will be attractive candidates for the design of new therapeutics and vaccines. [unreadable] [unreadable] [unreadable] [unreadable]..
- MACROPHAGE ACTIVATION AND LIPOPROTEIN METABOLISMMaria Lopes Virella; Fiscal Year: 2001..Our overall objective is to provide insight into the mechanisms by which anti-LDL antibodies and macrophage activation may contribute to the development(acceleration of the arteriosclerotic process. ..
- PROTEIN/RNA INTERACTIONS IN TRANSLATIONAL REGULATIONStephen Mayfield; Fiscal Year: 2005..4. Identify the roles of psbA associated proteins in translation by genetic analysis. 5. Characterize the role of RNA elements and trans-acting factors in translation initiation complex formation ..