chlamydiaceae

Summary

Summary: A family of gram-negative, coccoid microorganisms, in the order CHLAMYDIALES, pathogenic for vertebrates. Genera include CHLAMYDIA and CHLAMYDOPHILA.

Top Publications

  1. ncbi Characterization of Chlamydiaceae species using PCR and high resolution melt curve analysis of the 16S rRNA gene
    T Robertson
    School of Veterinary Science, The University of Melbourne, Werribee, Victoria, Australia
    J Appl Microbiol 107:2017-28. 2009
  2. ncbi Occurrence of Chlamydiaceae, Mycoplasma conjunctivae, and pestiviruses in Alpine chamois (Rupicapra r. rupicapra) of Grisons, Switzerland
    Nathalie Holzwarth
    Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 268, CH 8057 Zurich, Switzerland
    J Vet Diagn Invest 23:333-7. 2011
  3. ncbi Occurrence of Chlamydiaceae spp. in a wild boar (Sus scrofa L.) population in Thuringia (Germany)
    Helmut Hotzel
    Institute of Bacterial Infections and Zoonoses, Friedrich Loeffler Institut, Naumburger Strasse 96a, 07743 Jena, Germany
    Vet Microbiol 103:121-6. 2004
  4. pmc Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae
    T D Read
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Nucleic Acids Res 31:2134-47. 2003
  5. ncbi Structural and immunochemical analysis of the lipopolysaccharide from Acinetobacter lwoffii F78 located outside Chlamydiaceae with a Chlamydia-specific lipopolysaccharide epitope
    Anna Hanuszkiewicz
    Division of Structural Biochemistry, Research Center Borstel, Leibniz Center for Medicine and Biosciences, Parkallee 1 40, 23845 Borstel, Germany
    Chemistry 14:10251-8. 2008
  6. pmc Chlamydophila abortus in a Brown skua (Catharacta antarctica lonnbergi) from a subantarctic island
    B Herrmann
    Section of Virology, Department of Clinical Microbiology, University Hospital, S 751 85 Uppsala, Sweden
    Appl Environ Microbiol 66:3654-6. 2000
  7. pmc BLAST screening of chlamydial genomes to identify signature proteins that are unique for the Chlamydiales, Chlamydiaceae, Chlamydophila and Chlamydia groups of species
    Emma Griffiths
    Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, L8N 3Z5, Canada
    BMC Genomics 7:14. 2006
  8. ncbi Recombinant major outer membrane protein (MOMP) of Chlamydophila abortus, Chlamydophila pecorum, and Chlamydia suis as antigens to distinguish chlamydial species-specific antibodies in animal sera
    Ludwig E Hoelzle
    Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 270, CH 8057 Zurich, Switzerland
    Vet Microbiol 103:85-90. 2004
  9. ncbi Immunoblotting, ELISA and culture evidence for Chlamydiaceae in sows on 258 Belgian farms
    Daisy Vanrompay
    Department of Molecular Biotechnology, Faculty of Agricultural and Applied Biological Sciences, Ghent University, Coupure Links 653, B 9000 Ghent, Belgium
    Vet Microbiol 99:59-66. 2004
  10. ncbi High prevalence of antibodies against Chlamydiaceae and Chlamydophila abortus in wild ungulates using two "in house" blocking-ELISA tests
    J Salinas
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    Vet Microbiol 135:46-53. 2009

Research Grants

  1. Comparative Genomics of the Chlamydiaceae
    Garry Myers; Fiscal Year: 2007
  2. Pathogenesis of Persistent Chlamydial STDs
    Deborah Dean; Fiscal Year: 2007
  3. PATHOGENESIS OF CHLAMYDIAL OCULAR INFECTIONS
    Deborah Dean; Fiscal Year: 2004
  4. C. trachomatis genomics, strain typing, and evolution
    Deborah Dean; Fiscal Year: 2008
  5. Analysis of type III secreted proteins of C. trachomatis
    KENNETH FIELDS; Fiscal Year: 2005
  6. Chlamydia pneumoniae-Specific Inclusion Membrane Proteins
    KENNETH FIELDS; Fiscal Year: 2008
  7. VIRULENCE DETERMINANTS OF CHLAMYDIA
    Richard Stephens; Fiscal Year: 2007
  8. CHLAMYDIAL IMMUNITY AND PATHOGENESIS
    Richard Stephens; Fiscal Year: 2001
  9. MICROBIOLOGY OF CHLAMYDIA TRACHOMATIS ATTACHMENT
    Richard Stephens; Fiscal Year: 2005
  10. Cellular Microbiology of Chlamydia pneumoniae
    Richard Stephens; Fiscal Year: 2005

Detail Information

Publications156 found, 100 shown here

  1. ncbi Characterization of Chlamydiaceae species using PCR and high resolution melt curve analysis of the 16S rRNA gene
    T Robertson
    School of Veterinary Science, The University of Melbourne, Werribee, Victoria, Australia
    J Appl Microbiol 107:2017-28. 2009
    To design a rapid diagnostic test to differentiate species belonging to the family Chlamydiaceae.
  2. ncbi Occurrence of Chlamydiaceae, Mycoplasma conjunctivae, and pestiviruses in Alpine chamois (Rupicapra r. rupicapra) of Grisons, Switzerland
    Nathalie Holzwarth
    Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 268, CH 8057 Zurich, Switzerland
    J Vet Diagn Invest 23:333-7. 2011
    ..Thus, the occurrence of Chlamydiaceae, Mycoplasma conjunctivae, and pestiviruses in Alpine chamois (Rupicapra r...
  3. ncbi Occurrence of Chlamydiaceae spp. in a wild boar (Sus scrofa L.) population in Thuringia (Germany)
    Helmut Hotzel
    Institute of Bacterial Infections and Zoonoses, Friedrich Loeffler Institut, Naumburger Strasse 96a, 07743 Jena, Germany
    Vet Microbiol 103:121-6. 2004
    ..While the role of Chlamydiaceae as pathogens in wild boar has yet to be established, the present findings revealed a possible wildlife ..
  4. pmc Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae
    T D Read
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Nucleic Acids Res 31:2134-47. 2003
    ..a plasmid of 7966 nt) was determined, representing the fourth species with a complete genome sequence from the Chlamydiaceae family of obligate intracellular bacterial pathogens...
  5. ncbi Structural and immunochemical analysis of the lipopolysaccharide from Acinetobacter lwoffii F78 located outside Chlamydiaceae with a Chlamydia-specific lipopolysaccharide epitope
    Anna Hanuszkiewicz
    Division of Structural Biochemistry, Research Center Borstel, Leibniz Center for Medicine and Biosciences, Parkallee 1 40, 23845 Borstel, Germany
    Chemistry 14:10251-8. 2008
    ..lwoffii F78 LPS. Thus, an LPS was identified outside Chlamydiaceae that contains a Chlamydia-specific LPS epitope in its core region.
  6. pmc Chlamydophila abortus in a Brown skua (Catharacta antarctica lonnbergi) from a subantarctic island
    B Herrmann
    Section of Virology, Department of Clinical Microbiology, University Hospital, S 751 85 Uppsala, Sweden
    Appl Environ Microbiol 66:3654-6. 2000
    ..Phylogenetic analysis of the rnpB and omp1 genes indicated the strain to be more closely related to C. abortus than to 6BC, the type strain of Chlamydophila psittaci...
  7. pmc BLAST screening of chlamydial genomes to identify signature proteins that are unique for the Chlamydiales, Chlamydiaceae, Chlamydophila and Chlamydia groups of species
    Emma Griffiths
    Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, L8N 3Z5, Canada
    BMC Genomics 7:14. 2006
    ..The obligate intracellular nature of chlamydiae has also limited their genetic and biochemical studies. Thus, it is of importance to develop additional means for their identification and characterization...
  8. ncbi Recombinant major outer membrane protein (MOMP) of Chlamydophila abortus, Chlamydophila pecorum, and Chlamydia suis as antigens to distinguish chlamydial species-specific antibodies in animal sera
    Ludwig E Hoelzle
    Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 270, CH 8057 Zurich, Switzerland
    Vet Microbiol 103:85-90. 2004
    ..001). Preferential rMOMP ELISA reactivities of sera were confirmed by Western blotting. The results suggest that the entire chlamydial rMOMP could provide a species-specific serodiagnostic antigen...
  9. ncbi Immunoblotting, ELISA and culture evidence for Chlamydiaceae in sows on 258 Belgian farms
    Daisy Vanrompay
    Department of Molecular Biotechnology, Faculty of Agricultural and Applied Biological Sciences, Ghent University, Coupure Links 653, B 9000 Ghent, Belgium
    Vet Microbiol 99:59-66. 2004
    The prevalence of Chlamydiaceae infections on 258 closed pig breeding farms in Belgium was examined...
  10. ncbi High prevalence of antibodies against Chlamydiaceae and Chlamydophila abortus in wild ungulates using two "in house" blocking-ELISA tests
    J Salinas
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    Vet Microbiol 135:46-53. 2009
    ..In light of this, we have developed two in-house blocking-ELISA tests for detection of antibodies against Chlamydiaceae and C...
  11. ncbi Detection and differentiation of Chlamydiae by nested PCR
    Konrad Sachse
    Division 4 Bacterial Animal Diseases and Control of Zoonoses, Federal Institute for Health Protection of Consumers and Veterinary Medicine BgVV, Jena, Germany
    Methods Mol Biol 216:123-36. 2003
  12. pmc Evidence that plant-like genes in Chlamydia species reflect an ancestral relationship between Chlamydiaceae, cyanobacteria, and the chloroplast
    Fiona S L Brinkman
    Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada, V5A 1S6
    Genome Res 12:1159-67. 2002
    ..We present further evidence suggesting that plant-like genes in Chlamydia, and other Chlamydiaceae, are likely a reflection of an unappreciated evolutionary relationship between the Chlamydiaceae and the ..
  13. pmc Rapid detection of the Chlamydiaceae and other families in the order Chlamydiales: three PCR tests
    K D Everett
    Avian and Swine Respiratory Diseases Research Unit, USDA Agricultural Research Service, National Animal Disease Center, Ames, Iowa 50010, USA
    J Clin Microbiol 37:575-80. 1999
    Few identification methods will rapidly or specifically detect all bacteria in the order Chlamydiales, family Chlamydiaceae. In this study, three PCR tests based on sequence data from over 48 chlamydial strains were developed for ..
  14. ncbi Infectious causes for feline upper respiratory tract disease--a case-control study
    Bodil Ström Holst
    SLU, Department of Clinical Sciences, Box 7054, SE 750 07 Uppsala, Sweden
    J Feline Med Surg 12:783-9. 2010
    ..taken from the ventral conjunctival fornix for analysis of feline herpesvirus-1 (FHV), Mycoplasma felis and Chlamydiaceae using a real-time polymerase chain reaction technique...
  15. ncbi Molecular evolution of the Chlamydiaceae
    R M Bush
    Department of Ecology and Evolutionary Biology, University of California, Irvine 92697, USA
    Int J Syst Evol Microbiol 51:203-20. 2001
    ..analyses of surface antigens and other chlamydial proteins were used to reconstruct the evolution of the Chlamydiaceae. Trees for all five coding genes [the major outer-membrane protein (MOMP), GroEL chaperonin, KDO-transferase, ..
  16. pmc PCR detection and molecular identification of Chlamydiaceae species
    J C Hartley
    Department of Clinical Microbiology, University College London Hospital NHS Trust, London WC1E 6DB, United Kingdom
    J Clin Microbiol 39:3072-9. 2001
    Recent taxonomic developments, based on 16s and 23s rRNA gene sequences, have divided the family Chlamydiaceae into two genera and nine species, of which five have been found to infect humans...
  17. pmc Genomic plasticity of the rrn-nqrF intergenic segment in the Chlamydiaceae
    Zhi Liu
    Department of Biomedical Sciences, University of Maryland, Baltimore, MD 21201, USA
    J Bacteriol 189:2128-32. 2007
    In Chlamydiaceae, the nucleotide sequence between the 5S rRNA gene and the gene for subunit F of the Na(+)-translocating NADH-quinone reductase (nqrF or dmpP) has varied lengths and gene contents...
  18. ncbi Deep origin of plastid/parasite ATP/ADP translocases
    Haleh Amiri
    Department of Molecular Evolution, Evolutionary Biology Center, Uppsala University, Uppsala, Sweden
    J Mol Evol 56:137-50. 2003
    ..A possible function of the two types of ATP/ADP translocases was to allow switches between glycolysis and aerobic respiration in the early eukaryotic cell and its endosymbiont...
  19. ncbi Prevalence of Chlamydiaceae and Mollicutes on the genital mucosa and serological findings in dairy cattle
    Tom Petit
    Clinic for Obstetrics, Gynaecology and Andrology, University of Veterinary Sciences, 1210 Vienna, Austria
    Vet Microbiol 127:325-33. 2008
    It was the aim of this project to obtain information on the prevalence of Chlamydiaceae and Mollicutes and their potential importance for reproductive problems in cattle...
  20. pmc Interaction between components of the type III secretion system of Chlamydiaceae
    Anatoly Slepenkin
    Department of Pathology, Medical Science Building 1, Room D 440, University of California Irvine, Irvine, CA 92697 4800, USA
    J Bacteriol 187:473-9. 2005
    Members of the family Chlamydiaceae possess at least 13 genes, distributed throughout the chromosome, that are homologous with genes of known type III secretion systems (TTS)...
  21. ncbi Mixed infections in vitro with different Chlamydiaceae strains and a cell culture adapted porcine epidemic diarrhea virus
    Angela Stuedli
    Institute of Veterinary Pathology, University of Zurich, Winterthurerstrasse 268, CH 8057 Zurich, Switzerland
    Vet Microbiol 106:209-23. 2005
    Assuming a synergistic or additive effect of Chlamydiaceae in coexistence with other enteropathogenic agents, the viral/bacterial interaction between a cell culture adapted porcine epidemic diarrhea virus (ca-PEDV) and different ..
  22. ncbi Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards
    K D Everett
    Avian and Swine Respiratory Diseases Research Unit, National Animal Disease Center, US Department of Agriculture, Ames, IA 50010, USA or
    Int J Syst Bacteriol 49:415-40. 1999
    ..that the order Chlamydiales contains at least four distinct groups at the family level and that within the Chlamydiaceae are two distinct lineages which branch into nine separate clusters...
  23. ncbi Identification of nine species of the Chlamydiaceae using PCR-RFLP
    K D Everett
    Avian and Swine Respiratory Diseases Research Unit, National Animal Disease Center, US Department of Agriculture, Ames, IA 50010, USA
    Int J Syst Bacteriol 49:803-13. 1999
    The family Chlamydiaceae contains two genera and nine species. Rapid and easy identification of these species is essential for taxonomic, epidemiological and clinical determinations...
  24. pmc Pathogenic potential of novel Chlamydiae and diagnostic approaches to infections due to these obligate intracellular bacteria
    Daniele Corsaro
    Chlamydia Research Association, 12, rue du Maconnais, 54500 Vandoeuvres les Nancy, France
    Clin Microbiol Rev 19:283-97. 2006
    ..are newly recognized members of the phylum Chlamydiales that are only distantly related to the classic Chlamydiaceae, i.e., Chlamydia and Chlamydophila species...
  25. ncbi Development of a rapid real-time PCR assay for detection and quantification of four familiar species of Chlamydiaceae
    Jian Min Yang
    National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100094, PR China
    J Clin Virol 36:79-81. 2006
    ..Here, we presented a Chlamydiaceae-specific 23S rRNA-based real-time PCR assay for simultaneous detection and quantification of four members of ..
  26. ncbi Residual DNA in thermostable DNA polymerases - a cause of irritation in diagnostic PCR and microarray assays
    Ralf Ehricht
    CLONDIAG chip technologies GmbH, Loebstedter Strasse 103 105, 07749 Jena, Germany
    Biologicals 35:145-7. 2007
    ..coli DNA. When designing generic oligonucleotide sequences for PCR and PCR microarray-based assays one should be aware of such possible internal contamination, particularly when the target organism is E. coli...
  27. ncbi Evaluation of the phylogenetic position of the planctomycete 'Rhodopirellula baltica' SH 1 by means of concatenated ribosomal protein sequences, DNA-directed RNA polymerase subunit sequences and whole genome trees
    Hanno Teeling
    Max Planck Institute for Marine Microbiology, Celsiusstrasse 1, D 28359 Bremen, Germany
    Int J Syst Evol Microbiol 54:791-801. 2004
    ..Therefore, these analyses rather contradict a deep branching position of the Planctomycetes within the bacterial domain and reaffirm their earlier proposed relatedness to the Chlamydiae...
  28. pmc Dynamic diversity of the tryptophan pathway in chlamydiae: reductive evolution and a novel operon for tryptophan recapture
    Gary Xie
    Department of Microbiology and Cell Science, Gainesville, FL 32611, USA
    Genome Biol 3:research0051. 2002
    ..It appears that the chlamydiae have learned to recognize tryptophan depletion as a signal for developmental remodeling. The consequent non-cultivable state of persistence can be increasingly equated to chronic disease conditions...
  29. pmc Structure of bacterial tubulin BtubA/B: evidence for horizontal gene transfer
    Daniel Schlieper
    Laboratory of Molecular Biology, Medical Research Council, Hills Road, Cambridge CB2 2QH, United Kingdom
    Proc Natl Acad Sci U S A 102:9170-5. 2005
    ..Presumably, BtubA/B were transferred from a eukaryotic cell by horizontal gene transfer because their high degree of similarity to eukaryotic genes is unique within the Prosthecobacter genome...
  30. ncbi [Chlamydial diseases of domestic animals--zoonotic potential of the agents and diagnostic issues]
    K Sachse
    Nationales Veterinärmedizinisches Referenzlabor für Psittakose im Bundesinstitut für gesundheitlichen Verbraucherschutz und Veterinärmedizin, Fachbereich 4 Bakterielle Tierseuchen und Bekämpfung von Zoonosen, Jena
    Dtsch Tierarztl Wochenschr 109:142-8. 2002
    ..According to this proposal, the family Chlamydiaceae now comprises two genera (Chlamydia and Chlamydophila) with 9 largely host-related species...
  31. ncbi Examination of semen from bulls at five Austrian artificial insemination centres for chlamydiae and mollicutes
    T Petit
    Clinic for Obstetrics, Gynaecology and Andrology, University of Veterinary Sciences, 1210 Vienna, Austria
    Vet Rec 162:792-3. 2008
  32. ncbi Evaluation of lung function in pigs either experimentally or naturally infected with Chlamydiaceae
    P Reinhold
    Federal Research Institute for Animal Health, Institute of Molecular Pathogenesis, Naumburger Str 96a, 07743 Jena, Germany
    Vet Res Commun 29:125-50. 2005
    ..In conclusion, the consequences of respiratory chlamydial infections appear to vary from clinical inapparence to severe respiratory distress...
  33. ncbi Purifying and directional selection in overlapping prokaryotic genes
    Igor B Rogozin
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    Trends Genet 18:228-32. 2002
    ..This could be a general evolutionary mode for genes emerging from noncoding sequences, in which the protein sequence has not been subject to selection...
  34. pmc Reversal of the antichlamydial activity of putative type III secretion inhibitors by iron
    Anatoly Slepenkin
    Department of Pathology and Laboratory Medicine, Medical Science Building, Room D 440, University of California Irvine, Irvine, CA 92697 4800, USA
    Infect Immun 75:3478-89. 2007
    ..compounds belonging to a class of acylated hydrazones of salicylaldehydes, can inhibit the growth of Chlamydiaceae. Evidence has been presented that in Yersinia and Chlamydia INPs may affect the type III secretion (T3S) ..
  35. pmc HinT proteins and their putative interaction partners in Mollicutes and Chlamydiaceae
    Miriam Hopfe
    Institute of Medical Microbiology, Moorenstrasse 5, 40225 Duesseldorf, Germany
    BMC Microbiol 5:27. 2005
    ..In Mycoplasma hominis, HinT is concomitantly expressed with the proteins P60 and P80, two domains of a surface exposed membrane complex, and in addition interacts with the P80 moiety...
  36. ncbi Inclusion counter: a public domain image analysis system for measurement of Chlamydiaceae growth in vitro
    Jeremy K Brown
    Department of Veterinary Clinical Studies, Royal Dick School of Veterinary Studies, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG, UK
    J Microbiol Methods 51:323-9. 2002
    The traditional method of measuring chlamydial growth in vitro, counting Chlamydiaceae inclusions by eye, is time-consuming and error prone...
  37. pmc Multiple Chlamydiaceae species in trachoma: implications for disease pathogenesis and control
    Deborah Dean
    Center for Immunobiology and Vaccine Development, Children s Hospital Oakland Research Institute, Oakland, California, United States of America
    PLoS Med 5:e14. 2008
    ..Various animal models of trachoma show that urogenital C. trachomatis strains and other species of the family Chlamydiaceae produce severe conjunctival inflammation and scarring similar to that of the ocular C. trachomatis strains...
  38. pmc Independent inactivation of arginine decarboxylase genes by nonsense and missense mutations led to pseudogene formation in Chlamydia trachomatis serovar L2 and D strains
    Teresa N Giles
    Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, TX 78712, USA
    BMC Evol Biol 9:166. 2009
    ..All of the Chlamydiaceae have homologs of the aaxABC gene cluster that encodes a functional arginine:agmatine exchange system in ..
  39. ncbi Characterization of the rnpB gene and RNase P RNA in the order Chlamydiales
    B Herrmann
    Department of Clinical Microbiology, University Hospital, Uppsala, Sweden
    Int J Syst Evol Microbiol 50:149-58. 2000
    ..of the RNase P RNA gene (rnpB) was determined for 60 strains representing all nine species in the family Chlamydiaceae and for the related Chlamydiales species, Parachlamydia acanthamoebae and Simkania negevensis...
  40. pmc Natural cross chlamydial infection between livestock and free-living bird species
    Jesús A Lemus
    Departamento de Ecologia Evolutiva, Museo Nacional de Ciencias Naturales, CSIC, Madrid, Spain
    PLoS ONE 5:e13512. 2010
    ..We investigated whether gammapathies were associated with Chlamydiaceae infections...
  41. pmc Chlamydophila spp. infection in horses with recurrent airway obstruction: similarities to human chronic obstructive disease
    Dirk Theegarten
    Institute of Pathology and Neuropathology, University Duisburg Essen Medical School, Hufelandstr, 55, D 45122 Essen, Germany
    Respir Res 9:14. 2008
    ..The present study was designed (1) to clarify a possible role of this infectious agent in RAO and (2) to investigate the suitability of this equine disorder as a model for human COPD...
  42. pmc Caveolin-2 associates with intracellular chlamydial inclusions independently of caveolin-1
    Wilmore C Webley
    Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA
    BMC Infect Dis 4:23. 2004
    ..The Chlamydiaceae are obligate intracellular bacterial pathogens that replicate entirely within inclusions that develop from the ..
  43. pmc A genomic island present along the bacterial chromosome of the Parachlamydiaceae UWE25, an obligate amoebal endosymbiont, encodes a potentially functional F-like conjugative DNA transfer system
    Gilbert Greub
    Center for Research on Intracellular Bacteria, Institute of Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland
    BMC Microbiol 4:48. 2004
    ..The genome of Protochlamydia amoebophila UWE25, a Parachlamydia-related endosymbiont of free-living amoebae, was recently published, providing the opportunity to search for genomic islands (GIs)...
  44. ncbi Review of the carriage of zoonotic bacteria by arthropods, with special reference to Salmonella in mites, flies and litter beetles
    A D Wales
    Department of Food and Environmental Safety, Veterinary Laboratories Agency, New Haw, Addlestone, Surrey, UK
    Zoonoses Public Health 57:299-314. 2010
    ..Other members of the Enterobacteriaceae and the taxa Clostridium, Helicobacter, Erysipelas and Chlamydiaceae are also discussed...
  45. ncbi The Chlamydophila felis plasmid is highly conserved
    Ross Harley
    University of Bristol, School of Clinical Veterinary Science, Langford House, Langford, Bristol BS40 5DU, United Kingdom
    Vet Microbiol 146:172-4. 2010
    The presence of a plasmid in the Chlamydiaceae is both species and strain specific...
  46. ncbi Microbiological and pathological examination of fatal calf pneumonia cases induced by bacterial and viral respiratory pathogens
    Levente Szeredi
    Central Agricultural Office, Veterinary Diagnostic Directorate, Tábornok u 2, H 1149 Budapest, Hungary
    Acta Vet Hung 58:341-56. 2010
    ..5%) case. Mastadenovirus, bovine coronavirus, influenza A virus or Chlamydiaceae were not detected.
  47. ncbi Protein signatures distinctive of chlamydial species: horizontal transfers of cell wall biosynthesis genes glmU from archaea to chlamydiae and murA between chlamydiae and Streptomyces
    Emma Griffiths
    Department of Biochemistry, McMaster University, Hamilton, Ontario, CanadaL8N 3Z5
    Microbiology 148:2541-9. 2002
    ..All Chlamydiaceae species for which specific fragments could be amplified (Chlamydia suis, Chlamydophila abortus, Chlamydophila ..
  48. ncbi Identification and characterization of a type III secretion system in Chlamydophila psittaci
    Delphine Sylvie Anne Beeckman
    Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000 Ghent, Belgium
    Vet Res 39:27. 2008
    b>Chlamydiaceae are obligate intracellular Gram-negative bacteria replicating in vacuoles inside eukaryotic cells...
  49. pmc Recombination in the genome of Chlamydia trachomatis involving the polymorphic membrane protein C gene relative to ompA and evidence for horizontal gene transfer
    João P Gomes
    Department of Bacteriology, National Institute of Health, Lisbon, Portugal
    J Bacteriol 186:4295-306. 2004
    ..D has identified polymorphic membrane proteins (Pmp) that are a newly recognized protein family unique to the Chlamydiaceae family...
  50. pmc Molecular mechanism of tryptophan-dependent transcriptional regulation in Chlamydia trachomatis
    Johnny C Akers
    Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697 4025, USA
    J Bacteriol 188:4236-43. 2006
    ..The ability to synthesize tryptophan is not universal among the Chlamydiaceae, but species that have a predicted tryptophan biosynthetic pathway also encode an ortholog of TrpR, a ..
  51. pmc History of the ADP/ATP-translocase-encoding gene, a parasitism gene transferred from a Chlamydiales ancestor to plants 1 billion years ago
    Gilbert Greub
    Unite des Rickettsies, Faculte de Medecine, Universite de la Mediterranee, 13385 Marseille Cedex 05, France
    Appl Environ Microbiol 69:5530-5. 2003
    ..This gene shares more similarity with the tlc1 gene of Chlamydiaceae and the tlc of plant and alga plastids than with the tlc2 gene of Chlamydiaceae...
  52. ncbi Tackling the intractable - approaching the genetics of Chlamydiales
    Dagmar Heuer
    Department of Molecular Biology, Max Planck Institute for Infection Biology, Chariteplatz 1, D 10117 Berlin, Germany
    Int J Med Microbiol 297:569-76. 2007
    ..Despite intense research on Chlamydiaceae, the molecular genetic analysis of these pathogens remains difficult as genetic manipulation still remains ..
  53. ncbi Chlamydiales in guinea-pigs and their zoonotic potential
    L Lutz-Wohlgroth
    Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 268, CH 8057 Zurich, Switzerland
    J Vet Med A Physiol Pathol Clin Med 53:185-93. 2006
    ..A new Chlamydiaceae-specific intergenic spacer rRNA gene PCR, designed to amplify this segment linking the 16S and 23S regions, ..
  54. pmc Chlamydia trachomatis-infected patients display variable antibody profiles against the nine-member polymorphic membrane protein family
    Chun Tan
    Department of Microbial Pathogenesis, University of Maryland Dental School, Baltimore, 21201, USA
    Infect Immun 77:3218-26. 2009
    Genomic analysis of the Chlamydiaceae has revealed a multigene family encoding large, putatively autotransported polymorphic membrane proteins (Pmps) with nine members in the sexually transmitted pathogen Chlamydia trachomatis...
  55. pmc The Waddlia genome: a window into chlamydial biology
    Claire Bertelli
    Center for Research on Intracellular Bacteria, Institute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland
    PLoS ONE 5:e10890. 2010
    ..families of outer membrane proteins were identified indicating that these highly immunogenic proteins are not Chlamydiaceae specific and might have been present in their last common ancestor...
  56. pmc Predicting phenotype and emerging strains among Chlamydia trachomatis infections
    Deborah Dean
    Children s Global Health Initiativ, Children s Hospital Oakland Research Institute, Oakland, California 94609, USA
    Emerg Infect Dis 15:1385-94. 2009
    ..We used comparative genomics of the family Chlamydiaceae to select conserved housekeeping genes for C...
  57. pmc Molecular evidence for association of chlamydiales bacteria with epitheliocystis in leafy seadragon (Phycodurus eques), silver perch (Bidyanus bidyanus), and barramundi (Lates calcarifer)
    Adam Meijer
    Diagnostic Laboratory for Infectious Diseases and Screening, National Institute of Public Health and the Environment RIVM, PO Box 1, 3720 BA Bilthoven, The Netherlands
    Appl Environ Microbiol 72:284-90. 2006
    ..together with other chlamydia-like organisms in the order Chlamydiales in a lineage separate from the family Chlamydiaceae. By using in situ RNA hybridization, 16S rRNA Chlamydiales-specific sequences were detected in gill cysts of ..
  58. ncbi Identification and characterization of Inc766, an inclusion membrane protein in Chlamydophila abortus-infected cells
    Evangelia Vretou
    Laboratory of Biotechnology, Department of Microbiology, Hellenic Pasteur Institute, 127 Vassilissis Sofias Avenue, 11521 Athens, Greece
    Microb Pathog 45:265-72. 2008
    ..together, Inc766 displays unique biochemical and cellular features not encountered in other Incs from other Chlamydiaceae species...
  59. pmc Evolution of Chlamydia trachomatis diversity occurs by widespread interstrain recombination involving hotspots
    João P Gomes
    Center for Immunobiology and Vaccine Development, Children s Hospital Oakland Research Institute, Oakland, CA 94609, USA
    Genome Res 17:50-60. 2007
    ..Previous research shows that intracellular bacteria such as Chlamydiaceae may also undergo recombination but whether this plays a significant evolutionary role has not been determined...
  60. ncbi Identification and characterisation of coding tandem repeat variants in incA gene of Chlamydophila pecorum
    Khalil Yousef Mohamad
    INRA, UR1282, Infectiologie Animale et Sante Publique, Centre de Recherche de Tours, F 37380 Nouzilly, France
    Vet Res 39:56. 2008
    Bacteria of the family Chlamydiaceae are obligate intracellular pathogens of human and animals. Chlamydophila pecorum is associated with different pathological conditions in ruminants, swine and koala...
  61. pmc Rab6 and Rab11 regulate Chlamydia trachomatis development and golgin-84-dependent Golgi fragmentation
    Anette Rejman Lipinski
    Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany
    PLoS Pathog 5:e1000615. 2009
    ..Members of the Chlamydiaceae recruit a subset of Rab proteins to their inclusions, but the significance of these interactions is uncertain...
  62. pmc Uptake and intra-inclusion accumulation of exogenous immunoglobulin by Chlamydia-infected cells
    David V Pollack
    Department of Microbiology, University of Massachusetts, Amherst, Massachusetts 01002, USA
    BMC Microbiol 8:213. 2008
    Obligate intracellular pathogens belonging to the Chlamydiaceae family possess a number of mechanisms by which to manipulate the host cell and surrounding environment...
  63. ncbi Novel chlamydiae in whiteflies and scale insects: endosymbionts 'Candidatus Fritschea bemisiae' strain Falk and 'Candidatus Fritschea eriococci' strain Elm
    Karin D E Everett
    Department of Biology, University of Washington, Seattle, WA 98195 5325, USA
    Int J Syst Evol Microbiol 55:1581-7. 2005
    ..study compared sequences for 11 endosymbiont genes to genomic data for chlamydial families Parachlamydiaceae, Chlamydiaceae and Simkaniaceae and to 16S rRNA gene signature sequences from 330 chlamydiae...
  64. ncbi Chlamydia and Chlamydiales: more than meets the eye
    K D Everett
    Department of Medical Microbiology and Parasitology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    Vet Microbiol 75:109-26. 2000
    ..This review summarizes the pathogenic roles of the Chlamydiaceae, new families, and individual species within the order Chlamydiales...
  65. ncbi Intensively kept pigs pre-disposed to chlamydial associated conjunctivitis
    A Becker
    Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterhurerstrasse 268, CH 8057 Zurich, Switzerland
    J Vet Med A Physiol Pathol Clin Med 54:307-13. 2007
    ..In particular, the aim was to test pigs with and without clinical ocular symptoms for the presence of Chlamydiaceae and for linked infections with Acanthamoebae spp...
  66. ncbi Therapeutic approaches to Chlamydia infections
    Laurence Senn
    Department of Internal Medicine, University Hospital, Lausanne, Switzerland
    Expert Opin Pharmacother 6:2281-90. 2005
    ..Tetracyclines, macrolides and quinolones remain the antimicrobials of choice for the treatment of infections due to Chlamydiaceae.
  67. ncbi Proteomic analysis of the outer membrane of Protochlamydia amoebophila elementary bodies
    Eva Heinz
    Department of Microbial Ecology, Faculty of Life Sciences, University of Vienna, Austria
    Proteomics 10:4363-76. 2010
    ..So far the only experimental data for chlamydial outer membrane proteins are available from members of the Chlamydiaceae, a family comprising exclusively human and animal pathogens...
  68. ncbi Chlamydia-related abortions in cattle from Graubunden, Switzerland
    N Borel
    Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 268, CH 8057 Zurich, Switzerland
    Vet Pathol 43:702-8. 2006
    ..n = 235) from late-term abortions in cattle were analyzed by histopathology, immunohistochemistry with a Chlamydiaceae-specific monoclonal antibody against chlamydial lipopolysaccharide (LPS), and 2 different polymerase chain ..
  69. ncbi Genetic and pharmacological inhibition of poly(ADP-ribose) polymerase-1 interferes in the chlamydial life cycle
    Jose Yelamos
    Department of Biochemistry, Molecular Biology B and Immunology, University of Murcia, Murcia, Spain
    Biochem Biophys Res Commun 324:840-8. 2004
    b>Chlamydiaceae are intracellular bacteria responsible for a variety of infections, ranging from asymptomatic to very severe, in humans and animals...
  70. pmc Competitive inhibition of amino acid uptake suppresses chlamydial growth: involvement of the chlamydial amino acid transporter BrnQ
    Peter R Braun
    Department of Molecular Biology, Max Planck Institute for Infection Biology, Chariteplatz 1, 10117 Berlin, Germany
    J Bacteriol 190:1822-30. 2008
    b>Chlamydiaceae are obligate intracellular bacterial pathogens that strictly depend on host metabolites, such as nucleotides, lipids, and amino acids...
  71. ncbi Divergence without difference: phylogenetics and taxonomy of Chlamydia resolved
    Richard S Stephens
    University of California, Berkeley, USA
    FEMS Immunol Med Microbiol 55:115-9. 2009
    Members of Chlamydiaceae have been extensively characterized by complete genome sequencing. This information provides new understanding concerning their natural evolutionary history...
  72. pmc Members of the Pmp protein family of Chlamydia pneumoniae mediate adhesion to human cells via short repetitive peptide motifs
    Katja Mölleken
    Institut für Funktionelle Genomforschung der Mikroorganismen, Heinrich Heine Universitat Dusseldorf, Universitatsstr 1, Gebäude 25 02 U1, 40225 Dusseldorf, Germany
    Mol Microbiol 78:1004-17. 2010
    ..of the polymorphic membrane protein family (Pmp), the largest protein family (with up to 21 members) unique to Chlamydiaceae. We show that yeast cells displaying Pmp6, Pmp20 or Pmp21 on their surfaces, or beads coated with the ..
  73. ncbi Conjunctivitis due to Chlamydophila felis (Chlamydia psittaci feline pneumonitis agent) acquired from a cat: case report with molecular characterization of isolates from the patient and cat
    J C Hartley
    Department of Clinical Microbiology, UCLH Outpatient Building, Grafton Way, London, UK
    J Infect 43:7-11. 2001
    Conjunctivitis due to Chlamydiaceae other than Chlamydia trachomatis is rarely reported because of infrequent occurrence or inadequate investigation. A case of chronic non-trachomatis chlamydial conjunctivitis is described...
  74. ncbi Predator or prey? Chlamydophila abortus infections of a free-living amoebae, Acanthamoeba castellani 9GU
    Mirjam Wirz
    Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 268, CH 8057 Zurich, Switzerland
    Microbes Infect 10:591-7. 2008
    ..that the ability to invade and escape protozoan host cell bactericidal activity extends to members of the Chlamydiaceae, intracellular pathogens of humans and animals and evolutionary descendants of amoeba-resisting Chlamydia-like ..
  75. pmc Identification of protective epitopes by sequencing of the major outer membrane protein gene of a variant strain of Chlamydia psittaci serotype 1 (Chlamydophila abortus)
    E Vretou
    Department of Microbiology, Hellenic Pasteur Institute, Athens 115 21, Greece
    Infect Immun 69:607-12. 2001
    Protective monoclonal antibodies (MAbs) to the major outer membrane protein (MOMP) of species of the family Chlamydiaceae, which is the primary vaccine candidate antigen, recognize nonlinear epitopes conferred by the oligomeric ..
  76. ncbi DNA microarray-based detection and identification of Chlamydia and Chlamydophila spp
    Konrad Sachse
    Institute of Bacterial Infections and Zoonoses at the Federal Research Institute for Animal Health Friedrich Loeffler Institut, Naumburger Str 96a, 07743 Jena, Germany
    Mol Cell Probes 19:41-50. 2005
    ..Unique species-specific hybridization patterns were obtained for all nine species of the family Chlamydiaceae on both microarray types...
  77. pmc Chlamydophila abortus pelvic inflammatory disease
    Gernot Walder
    Institute of Hygiene and Social Medicine, University of Innsbruck, Innsbruck, Austria
    Emerg Infect Dis 9:1642-4. 2003
    ..The pathogen was identified in a patient with severe pelvic inflammatory disease (PID) by sequence analysis of the ompA gene. Our findings raise the possibility that Chlamydiaceae other than Chlamydia trachomatis are involved in PID.
  78. pmc Analysis of cross-reactive and specific anti-carbohydrate antibodies against lipopolysaccharide from Chlamydophila psittaci
    Sandra Gerstenbruch
    Research Center Borstel, Leibniz Center for Medicine and Biosciences, Parkallee 22, D 23845 Borstel, Germany
    Glycobiology 20:461-72. 2010
    ..8/2.4- and 2.4/2.4-linked, and a branched 2.4[2.8]2.4-linked Kdo tetrasaccharide occur in Chlamydiaceae. While the 2.8/2...
  79. ncbi Growth characteristics of porcine chlamydial strains in different cell culture systems and comparison with ovine and avian chlamydial strains
    Irene Schiller
    Institute of Veterinary Pathology, University of Zurich, Winterthurerstrasse 268, 8057 Zurich, Switzerland
    Vet J 168:74-80. 2004
    Porcine Chlamydiaceae were cultivated under various culture conditions and we compared their growth characteristics with those of ruminant and avian strains...
  80. pmc The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variation
    Nicholas R Thomson
    The Pathogen Sequencing Unit, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
    Genome Res 15:629-40. 2005
    ..and shows a high level of conservation in both sequence and overall gene content in comparison to other Chlamydiaceae. The 1,144,377-bp genome contains 961 predicted coding sequences, 842 of which are conserved with those of ..
  81. ncbi Seroprevalence of chlamydial infection in cattle in Ireland
    Kim Wilson
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian EH26OPZ, UK
    Vet J 193:583-5. 2012
    ..The assay detects antibodies to the two most common Chlamydiaceae spp. affecting cattle, namely Chlamydia abortus and Chlamydia pecorum...
  82. ncbi Transporter associated with antigen processing and the chaperone tapasin: are non-classical HLA genes keys to the pathogenesis of schizophrenia?
    Barbara Fellerhoff
    Institute for Immunology, University of Munich, Goethestrasse 31, D 80336 Munich, Germany
    Med Hypotheses 72:535-8. 2009
    ..Recently Chlamydiaceae species has been identified as a major factor in the pathogenesis of schizophrenia, suggesting defective ..
  83. ncbi Pregnancy, indoleamine 2,3-dioxygenase (IDO) and chlamydial abortion: an unresolved paradox
    Gary Entrican
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Midlothian EH26 0PZ, United Kingdom
    Vet Microbiol 135:98-102. 2009
    ..This paradox is discussed in the context of immune modulation during pregnancy, tryptophan biosynthesis by Chlamydiaceae and differences in placental structures between sheep, humans and mice.
  84. pmc Discovery of catalases in members of the Chlamydiales order
    Brigida Rusconi
    Institute of Microbiology, University of Lausanne and University Hospital Center, Lausanne, Switzerland
    J Bacteriol 195:3543-51. 2013
    Catalase is an important virulence factor for survival in macrophages and other phagocytic cells. In Chlamydiaceae, no catalase had been described so far...
  85. ncbi Clinicoimmunopathologic findings in Atlantic bottlenose dolphins Tursiops truncatus with positive Chlamydiaceae antibody titers
    Gregory D Bossart
    Georgia Aquarium, 225 Baker Street, NW, Atlanta, Georgia 30313, USA
    Dis Aquat Organ 108:71-81. 2014
    ..IRL), Florida, and coastal waters of Charleston (CHS), South Carolina, USA, were tested for antibodies to Chlamydiaceae as part of a multidisciplinary study of individual and population health...
  86. pmc Inclusion membrane proteins of Protochlamydia amoebophila UWE25 reveal a conserved mechanism for host cell interaction among the Chlamydiae
    Eva Heinz
    University of Vienna, Department of Microbial Ecology, Althanstrasse 14, A 1090 Vienna, Austria
    J Bacteriol 192:5093-102. 2010
    ..Among chlamydiae, inclusion membrane proteins have been exclusively found in members of the family Chlamydiaceae, which predominantly infect mammalian and avian hosts...
  87. ncbi Optimal development of Chlamydophila psittaci in L929 fibroblast and BGM epithelial cells requires the participation of microfilaments and microtubule-motor proteins
    C Escalante-Ochoa
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, R U G, Salisburylaan 133, Merelbeke, B 9820, Belgium
    Microb Pathog 28:321-33. 2000
    ..Evidence that mutual participation of the actin and tubulin networks in both host cells are required for optimal growth of Chlamydophila psittaci is also presented...
  88. ncbi Long-term monitoring of 10 selected pathogens in wild boar (Sus scrofa) in Sierra Nevada National Park, southern Spain
    Francisco J Cano-Manuel
    Espacio Natural Sierra Nevada, Carretera Antigua de Sierra Nevada, Km 7, E 18071, Pinos Genil, Granada, Spain Electronic address
    Vet Microbiol 174:148-54. 2014
    ..virus, porcine circovirus, porcine parvovirus, Erysipelotrix rhusiopathiae, Leptospira pomona, Chlamydia/Chlamydiaceae sp., Salmonella sp...
  89. pmc Effects of a probiotic strain of Enterococcus faecium on the rate of natural chlamydia infection in swine
    M Pollmann
    Institut für Mikrobiologie und Tierseuchen, Freie Universitat Berlin, Philippstrasse 13, 10115 Berlin, Germany
    Infect Immun 73:4346-53. 2005
    ..The presence of Chlamydiaceae was detected by species-specific PCR of fecal samples of sows taken at three times prior to the birth of ..
  90. ncbi Shedding of chlamydiae in relation to titers of serum chlamydiae-specific antibodies and serum concentrations of two acute-phase proteins in cats without conjunctivitis
    Bodil Ström Holst
    National Veterinary Institute, SE 751 89 Uppsala, Sweden
    Am J Vet Res 72:806-12. 2011
    ....
  91. ncbi Co-infection with two Chlamydophila species in a case of fulminant myocarditis
    Gernot Walder
    Department of Hygiene, Microbiology and Social Medicine, Innsbruck Medical University, Innsbruck, Austria
    Crit Care Med 35:623-6. 2007
    ....
  92. ncbi Chlamydia pneumoniae directly interferes with HIF-1alpha stabilization in human host cells
    Jan Rupp
    Institute of Medical Microbiology and Hygiene, Center for Structural and Cell Biology in Medicine, University of Luebeck, 23538 Luebeck, Germany
    Cell Microbiol 9:2181-91. 2007
    b>Chlamydiaceae are obligate intracellular bacteria that cause endemic trachoma, sexually transmitted diseases and respiratory infections...
  93. ncbi Permissivity of Vero cells, human pneumocytes and human endometrial cells to Waddlia chondrophila
    C Kebbi-Beghdadi
    Center for Research on Intracellular Bacteria CRIB, Institute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland
    Microbes Infect 13:566-74. 2011
    ..chondrophila coincided with the appearance of large aberrant bodies, a form of the bacteria also observed in Chlamydiaceae and associated with persistence. This persistent state of W...
  94. ncbi Genome sequence of the cat pathogen, Chlamydophila felis
    Yoshinao Azuma
    Department of Microbiology, Yamaguchi University School of Medicine, Ube, Yamaguchi 755 8505, Japan
    DNA Res 13:15-23. 2006
    ..felis gene contents with other Chlamydia species shows that 795 genes are common in the family Chlamydiaceae species and 47 genes are specific to C. felis...
  95. ncbi Associations between Chlamydophila infections, schizophrenia and risk of HLA-A10
    B Fellerhoff
    Institute of Immunology, Ludwig Maximilans University of Munich, Munich, Germany
    Mol Psychiatry 12:264-72. 2007
    ..Our aim here was to analyze frequencies of three types of Chlamydiaceae in schizophrenic patients (n=72), random controls (n=225) and hospital-patient controls (n=36), together with ..
  96. ncbi Comparative analyses of secondary gene products of 3-deoxy-D-manno-oct-2-ulosonic acid transferases from Chlamydiaceae in Escherichia coli K-12
    W Brabetz
    Division of Medical and Biochemical Microbiology, Research Centre Borstel, Centre for Medicine and Biosciences, Borstel, Germany
    Eur J Biochem 267:5458-65. 2000
    ..psittaci transfers predominantly four Kdo residues to lipid A, forming a branched tetrasaccharide with the structure alpha-Kdo-(2-->8)-[alpha-Kdo-(2-->4)]-alpha-Kdo-(2-->4)-alpha-Kdo...
  97. ncbi Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments
    Cory L Brooks
    University of Victoria, Department of Biochemistry and Microbiology, Victoria BC V8P 3P6, Canada
    Acta Crystallogr D Biol Crystallogr 64:1250-8. 2008
    ..The final R factor for SAG506-01 after refinement in P2(1)2(1)2(1) was 20.5%...
  98. ncbi Evolution, phylogeny, and molecular epidemiology of Chlamydia
    Alexandra Nunes
    Reference Laboratory of Bacterial Sexually Transmitted Infections and Bioinformatics Unit, Department of Infectious Diseases, National Institute of Health, Av Padre Cruz, 1649 016 Lisbon, Portugal
    Infect Genet Evol 23:49-64. 2014
    The Chlamydiaceae are a family of obligate intracellular bacteria characterized by a unique biphasic developmental cycle...
  99. pmc Functional analysis of the cytoskeleton protein MreB from Chlamydophila pneumoniae
    Ahmed Gaballah
    University of Bonn, Institute for Medical Microbiology, Immunology and Parasitology, Pharmaceutical Microbiology Section, Bonn, Germany
    PLoS ONE 6:e25129. 2011
    ..to compensate osmotic pressure by means of a cell wall, and peptidoglycan has not been reliably detected in Chlamydiaceae. Surprisingly, a nearly complete pathway for the biosynthesis of the cell wall building block lipid II has ..
  100. ncbi Molecular characterization of atypical Chlamydia and evidence of their dissemination in different European and Asian chicken flocks by specific real-time PCR
    Aleksandar Zocevic
    Bacterial Zoonoses Unit, French Agency for Food, Environmental and Occupational Health Safety ANSES, Maisons Alfort, France
    Environ Microbiol 14:2212-22. 2012
    ..potential were recently detected from domestic poultry in Germany and France indicating that the spectrum of Chlamydiaceae encountered in birds is not confined to a single chlamydial species...
  101. pmc Functional interaction between type III-secreted protein IncA of Chlamydophila psittaci and human G3BP1
    Nicole Borth
    Department of Cell and Molecular Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute, Jena, Germany
    PLoS ONE 6:e16692. 2011
    ..the causative agent of psittacosis in birds and humans, is the most important zoonotic pathogen of the family Chlamydiaceae. These obligate intracellular bacteria are distinguished by a unique biphasic developmental cycle, which ..

Research Grants11

  1. Comparative Genomics of the Chlamydiaceae
    Garry Myers; Fiscal Year: 2007
    ..novel, multifaceted approach, which we have named "Taxogenomics", is to first sequence the type strains of the Chlamydiaceae species not addressed by previous or current projects - C. suis, C. pecorum, and C...
  2. Pathogenesis of Persistent Chlamydial STDs
    Deborah Dean; Fiscal Year: 2007
    ..1 Description, ..
  3. PATHOGENESIS OF CHLAMYDIAL OCULAR INFECTIONS
    Deborah Dean; Fiscal Year: 2004
    ..A greater understanding of the pathogenesis of trachoma will aid in developing public health interventions and a vaccine that can be implemented in trachoma endemic areas throughout the world. ..
  4. C. trachomatis genomics, strain typing, and evolution
    Deborah Dean; Fiscal Year: 2008
    ..genetic discovery initiated by the CT genome sequences of serovars D and L2 and other genomes of the family Chlamydiaceae by providing genome sequences of six of the 13 remaining reference serovars along with genomes of recent ..
  5. Analysis of type III secreted proteins of C. trachomatis
    KENNETH FIELDS; Fiscal Year: 2005
    ..abstract_text> ..
  6. Chlamydia pneumoniae-Specific Inclusion Membrane Proteins
    KENNETH FIELDS; Fiscal Year: 2008
    ..We propose to study proteins that are i) unique to C. pneumoniae and ii) directly interfere with normal functions within human cells. [unreadable] [unreadable] [unreadable] [unreadable]..
  7. VIRULENCE DETERMINANTS OF CHLAMYDIA
    Richard Stephens; Fiscal Year: 2007
    ..coli. Based upon the information obtained from Aims 1 & 2, we will model chlamydial gene regulation in E. coli and test specific hypotheses of gene regulatory function. [unreadable] [unreadable]..
  8. CHLAMYDIAL IMMUNITY AND PATHOGENESIS
    Richard Stephens; Fiscal Year: 2001
    ....
  9. MICROBIOLOGY OF CHLAMYDIA TRACHOMATIS ATTACHMENT
    Richard Stephens; Fiscal Year: 2005
    ....
  10. Cellular Microbiology of Chlamydia pneumoniae
    Richard Stephens; Fiscal Year: 2005
    ..pneumoniae during persistent infection and during growth in different cell types. 4) Identify chlamydial products and test persistently-expressed C. pneumoniae gene products for their ability to induce host cell responses. ..
  11. Structure of Chlamydia-Specific Host Cell Vacuoles
    Richard S Stephens; Fiscal Year: 2010
    ..This research will establish the mechanism of microbial survival in cells that will serve as targets for prevention and control of chlamydial infection. ..