buchnera

Summary

Summary: A genus of gram-negative bacteria which are obligately intracellular endosymbionts of APHIDS. The bacteria are found within specialized cells in the aphid body cavity.

Top Publications

  1. ncbi Systemic analysis of the symbiotic function of Buchnera aphidicola, the primary endosymbiont of the pea aphid Acyrthosiphon pisum
    Lilia Brinza
    UMR203 BF2I, Biologie Fonctionnelle Insectes et Interactions, Universite de Lyon, INRA, INSA Lyon, IFR41, 20, avenue A Einstein, 69621 Villeurbanne, France
    C R Biol 332:1034-49. 2009
  2. pmc Facultative bacterial symbionts in aphids confer resistance to parasitic wasps
    Kerry M Oliver
    Department of Entomology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 100:1803-7. 2003
  3. pmc Serratia symbiotica from the aphid Cinara cedri: a missing link from facultative to obligate insect endosymbiont
    Araceli Lamelas
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Valencia, Spain
    PLoS Genet 7:e1002357. 2011
  4. pmc Aphid genome expression reveals host-symbiont cooperation in the production of amino acids
    Allison K Hansen
    Department of Ecology and Evolutionary Biology, Yale University, West Haven, CT 06516 7388, USA
    Proc Natl Acad Sci U S A 108:2849-54. 2011
  5. pmc Sequence conservation and functional constraint on intergenic spacers in reduced genomes of the obligate symbiont Buchnera
    Patrick H Degnan
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, United States of America
    PLoS Genet 7:e1002252. 2011
  6. pmc New clues about the evolutionary history of metabolic losses in bacterial endosymbionts, provided by the genome of Buchnera aphidicola from the aphid Cinara tujafilina
    Araceli Lamelas
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Apartado de Correos 2085, 46071 Valencia, Spain
    Appl Environ Microbiol 77:4446-54. 2011
  7. ncbi 50 million years of genomic stasis in endosymbiotic bacteria
    Ivica Tamas
    Department of Molecular Evolution, Evolutionary Biology Center, University of Uppsala, Uppsala, Sweden
    Science 296:2376-9. 2002
  8. pmc Bacterial genes in the aphid genome: absence of functional gene transfer from Buchnera to its host
    Naruo Nikoh
    Department of Liberal Arts, The Open University of Japan, Chiba, Japan
    PLoS Genet 6:e1000827. 2010
  9. pmc Extreme genome reduction in Buchnera spp.: toward the minimal genome needed for symbiotic life
    Rosario Gil
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Apartat Oficial 2085, 46071 Valencia, Spain
    Proc Natl Acad Sci U S A 99:4454-8. 2002
  10. ncbi Estimating population size and transmission bottlenecks in maternally transmitted endosymbiotic bacteria
    A Mira
    Department of Ecology and Evolutionary Biology, University of Arizona, PO Box 210088, Tucson, AZ 85721 0088, USA
    Microb Ecol 44:137-43. 2002

Research Grants

Detail Information

Publications173 found, 100 shown here

  1. ncbi Systemic analysis of the symbiotic function of Buchnera aphidicola, the primary endosymbiont of the pea aphid Acyrthosiphon pisum
    Lilia Brinza
    UMR203 BF2I, Biologie Fonctionnelle Insectes et Interactions, Universite de Lyon, INRA, INSA Lyon, IFR41, 20, avenue A Einstein, 69621 Villeurbanne, France
    C R Biol 332:1034-49. 2009
    b>Buchnera aphidicola is the primary obligate intracellular symbiont of most aphid species. B. aphidicola and aphids have been evolving in parallel since their association started, about 150 Myr ago...
  2. pmc Facultative bacterial symbionts in aphids confer resistance to parasitic wasps
    Kerry M Oliver
    Department of Entomology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 100:1803-7. 2003
    ..Aphids have an obligate association with the bacterium Buchnera aphidicola (the primary symbiont) that has been shown to contribute directly to aphid fitness...
  3. pmc Serratia symbiotica from the aphid Cinara cedri: a missing link from facultative to obligate insect endosymbiont
    Araceli Lamelas
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Valencia, Spain
    PLoS Genet 7:e1002357. 2011
    The genome sequencing of Buchnera aphidicola BCc from the aphid Cinara cedri, which is the smallest known Buchnera genome, revealed that this bacterium had lost its symbiotic role, as it was not able to synthesize tryptophan and ..
  4. pmc Aphid genome expression reveals host-symbiont cooperation in the production of amino acids
    Allison K Hansen
    Department of Ecology and Evolutionary Biology, Yale University, West Haven, CT 06516 7388, USA
    Proc Natl Acad Sci U S A 108:2849-54. 2011
    ..essential amino acids are scarce in the phloem sap diet and are supplied by the obligate bacterial endosymbiont (Buchnera), which lives inside specialized cells called bacteriocytes...
  5. pmc Sequence conservation and functional constraint on intergenic spacers in reduced genomes of the obligate symbiont Buchnera
    Patrick H Degnan
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, United States of America
    PLoS Genet 7:e1002252. 2011
    ..The genomes of Buchnera and other small genome symbionts display biased nucleotide compositions and high rates of sequence evolution and ..
  6. pmc New clues about the evolutionary history of metabolic losses in bacterial endosymbionts, provided by the genome of Buchnera aphidicola from the aphid Cinara tujafilina
    Araceli Lamelas
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Apartado de Correos 2085, 46071 Valencia, Spain
    Appl Environ Microbiol 77:4446-54. 2011
    The symbiotic association between aphids (Homoptera) and Buchnera aphidicola (Gammaproteobacteria) started about 100 to 200 million years ago...
  7. ncbi 50 million years of genomic stasis in endosymbiotic bacteria
    Ivica Tamas
    Department of Molecular Evolution, Evolutionary Biology Center, University of Uppsala, Uppsala, Sweden
    Science 296:2376-9. 2002
    Comparison of two fully sequenced genomes of Buchnera aphidicola, the obligate endosymbionts of aphids, reveals the most extreme genome stability to date: no chromosome rearrangements or gene acquisitions have occurred in the past 50 to ..
  8. pmc Bacterial genes in the aphid genome: absence of functional gene transfer from Buchnera to its host
    Naruo Nikoh
    Department of Liberal Arts, The Open University of Japan, Chiba, Japan
    PLoS Genet 6:e1000827. 2010
    ..Aphids harbor anciently acquired obligate mutualists, Buchnera aphidicola (Gammaproteobacteria), which have highly reduced genomes (420-650 kb), raising the possibility of gene ..
  9. pmc Extreme genome reduction in Buchnera spp.: toward the minimal genome needed for symbiotic life
    Rosario Gil
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Apartat Oficial 2085, 46071 Valencia, Spain
    Proc Natl Acad Sci U S A 99:4454-8. 2002
    b>Buchnera is a mutualistic intracellular symbiont of aphids. Their association began about 200 million years ago, with host and symbiont lineages evolving in parallel since that time...
  10. ncbi Estimating population size and transmission bottlenecks in maternally transmitted endosymbiotic bacteria
    A Mira
    Department of Ecology and Evolutionary Biology, University of Arizona, PO Box 210088, Tucson, AZ 85721 0088, USA
    Microb Ecol 44:137-43. 2002
    ..We have estimated the size of the transmission bottleneck in Buchnera, the bacterial symbiont of aphids, using basic light and electron microscopy techniques...
  11. pmc Genomic revelations of a mutualism: the pea aphid and its obligate bacterial symbiont
    Shuji Shigenobu
    NIBB Core Research Facilities, National Institute for Basic Biology, Myodaiji, Okazaki, Japan
    Cell Mol Life Sci 68:1297-309. 2011
    The symbiosis of the pea aphid Acyrthosphion pisum with the bacterium Buchnera aphidicola APS represents the best-studied insect obligate symbiosis...
  12. pmc Aphids acquired symbiotic genes via lateral gene transfer
    Naruo Nikoh
    Division of Natural Sciences, The Open University of Japan, Chiba, Japan
    BMC Biol 7:12. 2009
    Aphids possess bacteriocytes, which are cells specifically differentiated to harbour the obligate mutualist Buchnera aphidicola (gamma-Proteobacteria). Buchnera has lost many of the genes that appear to be essential for bacterial life...
  13. pmc A genomic reappraisal of symbiotic function in the aphid/Buchnera symbiosis: reduced transporter sets and variable membrane organisations
    Hubert Charles
    UMR203 BF2I, Biologie Fonctionnelle Insectes et Interactions, INSA Lyon, INRA, Universite de Lyon, Villeurbanne, France
    PLoS ONE 6:e29096. 2011
    b>Buchnera aphidicola is an obligate symbiotic bacterium that sustains the physiology of aphids by complementing their exclusive phloem sap diet...
  14. pmc Reduced selective constraint in endosymbionts: elevation in radical amino acid replacements occurs genome-wide
    Jennifer J Wernegreen
    Nicholas School of the Environment, Duke University, Durham, North Carolina, United States of America
    PLoS ONE 6:e28905. 2011
    ..against radical amino acid changes is less effective in two insect endosymbiont groups (Blochmannia of ants and Buchnera of aphids), compared to related gamma-Proteobacteria...
  15. pmc Reductive genome evolution in Buchnera aphidicola
    Roeland C H J van Ham
    Centro de Astrobiologia, Instituto Nacional de Técnica Aeroespacial Consejo Superior de Investigaciones Científicas, Carretera de Ajalvir kilómetro 4, 28850 Torrejon de Ardoz, Madrid, Spain
    Proc Natl Acad Sci U S A 100:581-6. 2003
    We have sequenced the genome of the intracellular symbiont Buchnera aphidicola from the aphid Baizongia pistacea. This strain diverged 80-150 million years ago from the common ancestor of two previously sequenced Buchnera strains...
  16. pmc Endosymbiont gene functions impaired and rescued by polymerase infidelity at poly(A) tracts
    Ivica Tamas
    Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, SE 752 36 Uppsala, Sweden
    Proc Natl Acad Sci U S A 105:14934-9. 2008
    ..Here, we demonstrate transcriptional slippage at poly(A) tracts within genes of Buchnera aphidicola associated with aphids and Blochmannia pennsylvanicus associated with ants...
  17. ncbi Phloem-sap feeding by animals: problems and solutions
    A E Douglas
    Department of Biology, University of York, PO Box 373, York YO10 5YW, UK
    J Exp Bot 57:747-54. 2006
    ..For example, bacteria of the genus Buchnera contribute up to 90% of the essential amino acids required by the pea aphid Acyrthosiphon pisum feeding on Vicia ..
  18. ncbi The dynamics and time scale of ongoing genomic erosion in symbiotic bacteria
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    Science 323:379-82. 2009
    ..We documented the dynamics of symbiont genome evolution by sequencing seven strains of Buchnera aphidicola from pea aphid hosts...
  19. ncbi Genome size reduction through multiple events of gene disintegration in Buchnera APS
    F J Silva
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva and Departament de Genètica, Universitat de Valencia, Apartado 22085, 46071, Valencia, Spain
    Trends Genet 17:615-8. 2001
    The evolution of the endosymbiont Buchnera during its adaptation to intracellular life involved a massive reduction in its genome...
  20. pmc Genetics coupled to quantitative intact proteomics links heritable aphid and endosymbiont protein expression to circulative polerovirus transmission
    M Cilia
    Robert W Holley Center for Agriculture and Health, Cornell University, Ithaca, NY 14853, USA
    J Virol 85:2148-66. 2011
    ..containing aphid proteins and proteins from the aphid's obligate and maternally inherited bacterial endosymbiont, Buchnera, were identified as differentially expressed between transmission-competent and refractive aphids...
  21. pmc A fragile metabolic network adapted for cooperation in the symbiotic bacterium Buchnera aphidicola
    Gavin H Thomas
    Department of Biology, University of York, PO Box 373, York, YO10 5YW, UK
    BMC Syst Biol 3:24. 2009
    ..coli genome...
  22. ncbi Consequences of reductive evolution for gene expression in an obligate endosymbiont
    Jennifer L Wilcox
    Department of Ecology and Evolutionary Biology, University of Arizona, BioSciences West Rm 310, Tucson 85721, USA
    Mol Microbiol 48:1491-500. 2003
    ..capacities, we used full-genome microarrays to evaluate transcriptional response to environmental stress in Buchnera aphidicola, the obligate endosymbiont of aphids. The 580 genes of the B...
  23. pmc Impact of host developmental age on the transcriptome of the symbiotic bacterium Buchnera aphidicola in the pea aphid (Acyrthosiphon pisum)
    John Bermingham
    School of Biology and Environmental Science, University College Dublin, Belfield, Dublin 4, Ireland
    Appl Environ Microbiol 75:7294-7. 2009
    Of the 617 genes from Buchnera aphidicola, the obligate bacterial symbiont of the pea aphid, 23% were differentially expressed in embryos compared to adults...
  24. ncbi Effects of facultative symbionts and heat stress on the metabolome of pea aphids
    Gaelen Burke
    Ecology and Evolutionary Biology, The University of Arizona, Tucson, AZ, USA
    ISME J 4:242-52. 2010
    ..symbiotica protects aphid hosts from the detrimental results of heat stress and shields the obligate symbiont Buchnera from effects of heat. We investigated whether broad effects on metabolism might correlate with this protection...
  25. pmc Multimodal dynamic response of the Buchnera aphidicola pLeu plasmid to variations in leucine demand of its host, the pea aphid Acyrthosiphon pisum
    José Viñuelas
    UMR203 BF2I, Biologie Fonctionnelle Insectes et Interactions, INSA Lyon, INRA, Universite de Lyon, Bat Louis Pasteur, 20 av Albert Einstein, F 69621 Villeurbanne, France
    Mol Microbiol 81:1271-85. 2011
    ..agricultural pests, can grow and reproduce thanks to their intimate symbiosis with the γ-proteobacterium Buchnera aphidicola that furnishes them with essential amino acids lacking in their phloem sap diet. To study how B...
  26. ncbi Two species of symbiotic bacteria present in the soybean aphid (Hemiptera: Aphididae)
    B D Wille
    Department of Entomology, University of Maryland, College Park, MD 20742, USA
    Environ Entomol 38:110-5. 2009
    ..Three soybean aphid (Aphis glycines Mat samura) populations were screened for the presence of Buchnera aphidicola and three common species of secondary aphid symbionts (Serratia symbiotica, Hamiltonella defensa, and ..
  27. pmc Transcriptome analysis of the aphid bacteriocyte, the symbiotic host cell that harbors an endocellular mutualistic bacterium, Buchnera
    Atsushi Nakabachi
    Environmental Molecular Biology Laboratory and Genome Science Laboratory, RIKEN, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Proc Natl Acad Sci U S A 102:5477-82. 2005
    ..possess bacteriocytes, cells specifically differentiated to harbor obligatory mutualistic bacteria of the genus Buchnera, which have lost many genes that are essential for common bacterial functions...
  28. ncbi Genome reduction of the aphid endosymbiont Buchnera aphidicola in a recent evolutionary time scale
    Laura Gomez-Valero
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva and Departament de Genètica, Universitat de Valencia, Apartat 22085, 46071 Valencia, Spain
    Gene 389:87-95. 2007
    Genome reduction, a typical feature of symbiotic bacteria, was analyzed in the last stages of evolution of Buchnera aphidicola, the primary aphid endosymbiont, in two neutrally evolving regions: the pseudogene cmk and an intergenic region...
  29. pmc Aphid thermal tolerance is governed by a point mutation in bacterial symbionts
    Helen E Dunbar
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona, United States of America
    PLoS Biol 5:e96. 2007
    ..A model of obligate symbiosis is that between aphids and the bacterium Buchnera aphidicola, which supplies essential nutrients...
  30. pmc Conservation of the links between gene transcription and chromosomal organization in the highly reduced genome of Buchnera aphidicola
    José Viñuelas
    UMR 203 Biologie Fonctionnelle Insectes et Interactions, IFR41, INRA, INSA Lyon, Villeurbanne, France
    BMC Genomics 8:143. 2007
    ..the possible conservation of relationships between mRNA abundances and chromosomal organization in the highly reduced genome of Buchnera aphidicola, the primary endosymbiont of the aphids, and a close relative to Escherichia coli.
  31. pmc Regulation of transcription in a reduced bacterial genome: nutrient-provisioning genes of the obligate symbiont Buchnera aphidicola
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
    J Bacteriol 187:4229-37. 2005
    b>Buchnera aphidicola, the obligate symbiont of aphids, has an extremely reduced genome, of which about 10% is devoted to the biosynthesis of essential amino acids needed by its hosts...
  32. ncbi Genome expansion and differential expression of amino acid transporters at the aphid/Buchnera symbiotic interface
    Daniel R G Price
    Department of Biology, University of Miami, Coral Gables, FL, USA
    Mol Biol Evol 28:3113-26. 2011
    ..One such symbiosis is the ancient obligate intracellular symbiosis of aphids with the γ-proteobacteria, Buchnera aphidicola...
  33. ncbi Molecular characterization of the leucine plasmid from Buchnera aphidicola, primary endosymbiont of the aphid Acyrthosiphon pisum
    T Soler
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva and Departament de Genètica, Universitat de Valencia, Apartat 22085, 46071 Valencia, Spain
    Curr Microbiol 40:264-8. 2000
    The complete sequence of the leucine plasmid of Buchnera aphidicola from the aphid Acyrthosiphon pisum (pLeu-BAp) is reported...
  34. ncbi Genetic and metabolic determinants of nutritional phenotype in an insect-bacterial symbiosis
    S J MacDonald
    Department of Biology, University of York, York YO10 5DD, UK
    Mol Ecol 20:2073-84. 2011
    ..of resident microorganisms on the phenotype of their hosts is exemplified by the intracellular bacterium Buchnera aphidicola, which provides its aphid partner with essential amino acids (EAAs)...
  35. pmc Intraspecific variation in symbiont genomes: bottlenecks and the aphid-buchnera association
    D J Funk
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    Genetics 157:477-89. 2001
    b>Buchnera are maternally transmitted bacterial endosymbionts that synthesize amino acids that are limiting in the diet of their aphid hosts...
  36. ncbi Age- and morph-dependent activation of the lysosomal system and Buchnera degradation in aphid endosymbiosis
    Kenji Nishikori
    Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Insect Physiol 55:351-7. 2009
    ..Endosymbiosis in aphids is maintained through a mutualistic association between the host and a symbiotic bacterium, Buchnera, which is harbored in specialized host cells called bacteriocytes...
  37. pmc Rickettsia symbiont in the pea aphid Acyrthosiphon pisum: novel cellular tropism, effect on host fitness, and interaction with the essential symbiont Buchnera
    Makiko Sakurai
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba 305 8566, Japan
    Appl Environ Microbiol 71:4069-75. 2005
    ..the effects of the Rickettsia symbiont on the host aphid and also on the coexisting essential symbiont Buchnera. In situ hybridization revealed that the Rickettsia symbiont was specifically localized in two types of host ..
  38. ncbi The evolution of the heat-shock protein GroEL from Buchnera, the primary endosymbiont of aphids, is governed by positive selection
    Mario Ali Fares
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva and Department de Genètica, Universitat de Valencia, Spain
    Mol Biol Evol 19:1162-70. 2002
    ..in the primary symbiotic bacteria of many insects, constituting approximately 10% of the total protein in Buchnera, the primary endosymbiont of aphids...
  39. pmc The players in a mutualistic symbiosis: insects, bacteria, viruses, and virulence genes
    Nancy A Moran
    Departments of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 87521, USA
    Proc Natl Acad Sci U S A 102:16919-26. 2005
    ..All possess a primary endosymbiont, Buchnera, which compensates for dietary deficiencies; many also contain secondary symbionts, such as Hamiltonella defensa, ..
  40. ncbi Chromosomal stasis versus plasmid plasticity in aphid endosymbiont Buchnera aphidicola
    A Latorre
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Apartado de Correos 2085, 46071 Valencia, Spain
    Heredity (Edinb) 95:339-47. 2005
    The study of three genomes of the aphid endosymbiont Buchnera aphidicola has revealed an extraordinary stasis: conservation of gene order and genetic composition of the chromosome, while the chromosome size and number of genes has reduced...
  41. pmc Evolution of the secondary symbiont "Candidatus serratia symbiotica" in aphid species of the subfamily lachninae
    Araceli Lamelas
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Apartado de Correos 22085, 46071 Valencia, Spain
    Appl Environ Microbiol 74:4236-40. 2008
    b>Buchnera aphidicola BCc, the primary endosymbiont of the aphid Cinara cedri (subfamily Lachninae), is losing its symbiotic capacity and might be replaced by the coresident "Candidatus Serratia symbiotica...
  42. ncbi Low and homogeneous copy number of plasmid-borne symbiont genes affecting host nutrition in Buchnera aphidicola of the aphid Uroleucon ambrosiae
    Gordon R Plague
    Center for Insect Science, University of Arizona, Tucson, AZ 85721, USA
    Mol Ecol 12:1095-100. 2003
    The bacterial endosymbiont of aphids, Buchnera aphidicola, often provides amino acids to its hosts...
  43. ncbi Functional genomics of Buchnera and the ecology of aphid hosts
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
    Mol Ecol 15:1251-61. 2006
    ..Among such symbionts, genomic studies are most advanced for Buchnera, the obligate symbiont of aphids, which feed on phloem sap...
  44. pmc Hundreds of flagellar basal bodies cover the cell surface of the endosymbiotic bacterium Buchnera aphidicola sp. strain APS
    Kazuki Maezawa
    Prefectural University of Hiroshima, Department of Life Sciences, 562 Nanatsuka, Shobara, Hiroshima 727 0023, Japan
    J Bacteriol 188:6539-43. 2006
    b>Buchnera aphidicola is the endosymbiotic bacterium of the pea aphid. Due to its small genome size, Buchnera lacks many essential genes for autogenous life but obtains nutrients from the host...
  45. pmc Evolution and diversity of facultative symbionts from the aphid subfamily Lachninae
    Gaelen R Burke
    Department of Ecology and Evolutionary Biology, University of Arizona, 1041 East Lowell Street, Tucson, Arizona 85721 0088, USA
    Appl Environ Microbiol 75:5328-35. 2009
    ..Serratia symbiotica" with Cinara subgenus Cinara species and weigh against an obligate nutritional role. Finally, we show that species belonging to the subfamily Lachninae have a high incidence of facultative symbiont infection...
  46. ncbi The evolution of the flagellar assembly pathway in endosymbiotic bacterial genomes
    Christina Toft
    Department of Genetics, Smurfit Institute of Genetics, University of Dublin, Trinity College, Dublin, Ireland
    Mol Biol Evol 25:2069-76. 2008
    ..Based on our results, we suggest that genes of flagellum have diverged functionally as to specialize in the export of proteins from the bacterium to the host...
  47. pmc Large-scale label-free quantitative proteomics of the pea aphid-Buchnera symbiosis
    Anton Poliakov
    Department of Plant Biology, Cornell University, Ithaca, NY 14853, USA
    Mol Cell Proteomics 10:M110.007039. 2011
    ..The obligate symbiosis between the pea aphid Acyrthosiphon pisum and the γ-proteobacterium Buchnera aphidicola (only 584 predicted proteins) is particularly amenable for molecular analysis because the genomes of ..
  48. pmc Structure and dynamics of the operon map of Buchnera aphidicola sp. strain APS
    Lilia Brinza
    INSA Lyon, UMR203 BF2I, INRA, Biologie Fonctionnelle Insectes et Interactions, Bat, Louis Pasteur 20 ave, Albert Einstein, F 69621 Villeurbanne, France
    BMC Genomics 11:666. 2010
    ..Understanding the evolution and mechanisms underlying the regulation of gene transcription in Buchnera aphidicola, the primary endosymbiont of aphids, is expected both to enhance our understanding of this ..
  49. pmc Coexistence of Wolbachia with Buchnera aphidicola and a secondary symbiont in the aphid Cinara cedri
    Laura Gomez-Valero
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Valencia, Spain
    J Bacteriol 186:6626-33. 2004
    ..PCR amplification and sequencing of the 16S ribosomal DNA (rDNA) genes showed that, in addition to harboring Buchnera aphidicola, the primary endosymbiont of aphids, C...
  50. pmc The striking case of tryptophan provision in the cedar aphid Cinara cedri
    María José Gosalbes
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Apartado de Correos 2085, 46071 Valencia, Spain
    J Bacteriol 190:6026-9. 2008
    b>Buchnera aphidicola BCc has lost its symbiotic role as the tryptophan supplier to the aphid Cinara cedri. We report the presence of a plasmid in this endosymbiont that contains the trpEG genes...
  51. ncbi The evolutionary fate of nonfunctional DNA in the bacterial endosymbiont Buchnera aphidicola
    Laura Gomez-Valero
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva and Departament de Genètica, Universitat de Valencia, 46071 Valencia, Spain
    Mol Biol Evol 21:2172-81. 2004
    ..We have analyzed the fate of the nonfunctional DNA in Buchnera aphidicola, the primary endosymbiont of aphids...
  52. ncbi Extremely low levels of genetic polymorphism in endosymbionts (Buchnera) of aphids (Pemphigus)
    P Abbot
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    Mol Ecol 11:2649-60. 2002
    ..for patterns of intraspecific polymorphism were borne out in the single relevant study available, on the symbiont Buchnera aphidicola of Uroleucon ambrosiae...
  53. ncbi Assessment of 35mer amino-modified oligonucleotide based microarray with bacterial samples
    Federica Calevro
    UMR INRA INSA 203, Laboratoire de Biologie Fonctionnelle, Insectes et Interactions, INSA Lyon, 20 Avenue Albert Einstein, 69621 Villeurbanne Cedex, France
    J Microbiol Methods 57:207-18. 2004
    ..The intracellular symbiotic bacterium of aphids, Buchnera aphidicola, is used here as a model organism...
  54. ncbi Genomic insight into the amino acid relations of the pea aphid, Acyrthosiphon pisum, with its symbiotic bacterium Buchnera aphidicola
    A C C Wilson
    Department of Biology, University of Miami, Coral Gables, FL 33146, USA
    Insect Mol Biol 19:249-58. 2010
    ..In several respects, the pea aphid gene inventory complements that of its symbiotic bacterium, Buchnera aphidicola (Buchnera APS)...
  55. pmc Evolution of the leucine gene cluster in Buchnera aphidicola: insights from chromosomal versions of the cluster
    Beatriz Sabater-Muñoz
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, 46071 Valencia, Spain
    J Bacteriol 186:2646-54. 2004
    In Buchnera aphidicola strains associated with the aphid subfamilies Thelaxinae, Lachninae, Pterocommatinae, and Aphidinae, the four leucine genes (leuA, -B, -C, and -D) are located on a plasmid...
  56. pmc Acceleration of genomic evolution caused by enhanced mutation rate in endocellular symbionts
    Takeshi Itoh
    Institute of Molecular Evolutionary Genetics and Department of Biology, Pennsylvania State University, 328 Mueller Laboratory, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 99:12944-8. 2002
    ..Here we compared the complete genome sequences of two different endosymbionts, Buchnera and a protist mitochondrion, with their close relatives to study the evolutionary rates of functional genes in ..
  57. ncbi A strong effect of AT mutational bias on amino acid usage in Buchnera is mitigated at high-expression genes
    Carmen Palacios
    Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, Woods Hole, Massachusetts 02543, USA
    Mol Biol Evol 19:1575-84. 2002
    ..analysis to determine the processes driving genome-wide patterns of amino usage in the obligate endosymbiont Buchnera and its close free-living relative Escherichia coli...
  58. ncbi Structural calibration of the rates of amino acid evolution in a search for Darwin in drifting biological systems
    Christina Toft
    Evolutionary Genetics and Bioinformatics Laboratory, Department of Genetics, University of Dublin, Trinity College, Dublin, Ireland
    Mol Biol Evol 27:2375-85. 2010
    ..This is, to our knowledge, the first attempt to distinguish adaptive evolution from relaxed constraints in biological systems under genetic drift...
  59. ncbi Genomic evidence for complementary purine metabolism in the pea aphid, Acyrthosiphon pisum, and its symbiotic bacterium Buchnera aphidicola
    J S Ramsey
    Boyce Thompson Institute, Ithaca, NY 14853, USA
    Insect Mol Biol 19:241-8. 2010
    ..Purine metabolism genes in the symbiotic bacterium Buchnera complement aphid genes, and Buchnera can meet its nucleotide requirement from aphid-derived guanosine...
  60. ncbi Plasmids in the aphid endosymbiont Buchnera aphidicola with the smallest genomes. A puzzling evolutionary story
    Rosario Gil
    Instituto Cavanilles de Biodiversidad y Biologia Evolutiva, Universidad de Valencia, Apartado de Correos 2085, 46071 Valencia, Spain
    Gene 370:17-25. 2006
    b>Buchnera aphidicola, the primary endosymbiont of aphids, has undergone important genomic and biochemical changes as an adaptation to intracellular life...
  61. ncbi Interactions between a luteovirus and the GroEL chaperonin protein of the symbiotic bacterium Buchnera aphidicola of aphids
    Sophie Bouvaine
    Department of Biology, University of York, York, UK
    J Gen Virol 92:1467-74. 2011
    ..A chaperonin protein, GroEL, synthesized in aphids by a symbiotic bacterium, Buchnera aphidicola, is hypothesized to bind to virus particles in the haemolymph, thereby promoting transmission...
  62. ncbi Quantifying nutrient production by the microbial symbionts in an aphid
    A E Douglas
    Department of Biology, University of York, York YO10 5YW, UK
    J Exp Biol 204:349-58. 2001
    The symbiotic bacteria Buchnera sp. provide aphids with essential amino acids, nutrients in short supply in the aphid diet of plant phloem sap...
  63. pmc Strict host-symbiont cospeciation and reductive genome evolution in insect gut bacteria
    Takahiro Hosokawa
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    PLoS Biol 4:e337. 2006
    ..a distinct group in the gamma-Proteobacteria, whose sister group was the aphid obligate endocellular symbionts Buchnera. Removal of the symbionts resulted in retarded growth, mortality, and sterility of the insects...
  64. ncbi Genetics. The bacterial world gets smaller
    Siv G E Andersson
    Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, Norbyvagen 18C, 752 36 Uppsala, Sweden
    Science 314:259-60. 2006
  65. pmc Different levels of transcriptional regulation due to trophic constraints in the reduced genome of Buchnera aphidicola APS
    Nancie Reymond
    UMR 203 INRA INSA de Lyon, Biologie Fonctionnelle Insectes et Interactions BF2I, INSA, Bat Louis Pasteur, 69621 Villeurbanne Cedex, France
    Appl Environ Microbiol 72:7760-6. 2006
    ..b>Buchnera aphidicola, the obligate intracellular bacterium associated with most aphid species, provides its hosts with ..
  66. ncbi Gene expression levels influence amino acid usage and evolutionary rates in endosymbiotic bacteria
    Jörg Schaber
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, A C 22085, 46071 Valencia, Spain
    Gene 352:109-17. 2005
    ....
  67. pmc Metabolic interdependence of obligate intracellular bacteria and their insect hosts
    Evelyn Zientz
    Lehrstuhl fur Mikrobiologie, Biozentrum der Universität Würzburg, Theodor Boveri Institut, Am Hubland, D 97074 Wurzburg, Germany
    Microbiol Mol Biol Rev 68:745-70. 2004
    ..This review attempts to provide insights into the complex physiological interactions and the evolution of metabolic pathways of several mutualistic bacteria of aphids, ants, and tsetse flies and their insect hosts...
  68. pmc Codon usage bias and tRNA over-expression in Buchnera aphidicola after aromatic amino acid nutritional stress on its host Acyrthosiphon pisum
    Hubert Charles
    Laboratoire de Biologie Fonctionnelle Insectes et Interactions, UMR INRA INSA de Lyon, 203 Bâtiment Louis Pasteur, 69621 Villeurbanne Cedex, France
    Nucleic Acids Res 34:4583-92. 2006
    ..and relative abundances of tRNA isoacceptors were analysed in the obligate intracellular symbiotic bacterium, Buchnera aphidicola from the aphid Acyrthosiphon pisum, using a dedicated 35mer oligonucleotide microarray...
  69. ncbi A small microbial genome: the end of a long symbiotic relationship?
    Vicente Perez-Brocal
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Apartado Postal 22085, 46071 Valencia, Spain
    Science 314:312-3. 2006
    Intracellular bacteria are characterized by genome reduction. The 422,434-base pair genome of Buchnera aphidicola BCc, primary endosymbiont of the aphid Cinara cedri, is approximately 200 kilobases smaller than the previously sequenced B...
  70. pmc Modular organization in the reductive evolution of protein-protein interaction networks
    Javier Tamames
    Instituto Cavanilles de Biodiversidad y Biologia Evolutiva, Universitat de Valencia, 46071 Valencia, Spain
    Genome Biol 8:R94. 2007
    ..High-throughput protein interaction data now make it possible to examine the additional complexity generated by the way that protein interactions are organized...
  71. ncbi Chance and necessity in the evolution of minimal metabolic networks
    Csaba Pal
    European Molecular Biology Laboratory, Meyerhofstrasse 1, D 69012 Heidelberg, Germany
    Nature 440:667-70. 2006
    ..by simulating their respective environmental conditions, we can model evolution of the gene content in Buchnera aphidicola and Wigglesworthia glossinidia with over 80% accuracy...
  72. pmc A dual-genome microarray for the pea aphid, Acyrthosiphon pisum, and its obligate bacterial symbiont, Buchnera aphidicola
    Alex C C Wilson
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    BMC Genomics 7:50. 2006
    The best studied insect-symbiont system is that of aphids and their primary bacterial endosymbiont Buchnera aphidicola...
  73. ncbi BuchneraBASE: a post-genomic resource for Buchnera sp. APS
    M Dennis Prickett
    Department of Biology, University of York, York YO10 5YW, UK
    Bioinformatics 22:641-2. 2006
    BuchneraBASE is a bioinformatic research tool for the genome of the symbiotic bacterium Buchnera sp...
  74. pmc Changing partners in an obligate symbiosis: a facultative endosymbiont can compensate for loss of the essential endosymbiont Buchnera in an aphid
    Ryuichi Koga
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Tsukuba 305 8566, Japan
    Proc Biol Sci 270:2543-50. 2003
    Almost all aphids harbour an endosymbiotic bacterium, Buchnera aphidicola, in bacteriocytes. Buchnera synthesizes essential nutrients and supports growth and reproduction of the host...
  75. pmc A conservative test of genetic drift in the endosymbiotic bacterium Buchnera: slightly deleterious mutations in the chaperonin groEL
    Joshua T Herbeck
    Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, Woods Hole, Massachusetts 02543, USA
    Genetics 165:1651-60. 2003
    The obligate endosymbiotic bacterium Buchnera aphidicola shows elevated rates of sequence evolution compared to free-living relatives, particularly at nonsynonymous sites...
  76. ncbi Morph-dependent expression and subcellular localization of host serine carboxypeptidase in bacteriocytes of the pea aphid associated with degradation of the endosymbiotic bacterium Buchnera
    Kenji Nishikori
    Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo 113 0033, Japan
    Zoolog Sci 26:415-20. 2009
    Pea aphids form a mutualistic association with the endosymbiotic bacterium Buchnera, which is harbored in specialized host cells called bacteriocytes. The adult aphids display dimorphism In which there are winged and wingless morphs...
  77. ncbi Comparative molecular evolution of primary (Buchnera) and secondary symbionts of aphids based on two protein-coding genes
    Andres Moya
    Instituto Cavanilles de Biodiversidad y Biología Evolutiva and Departamento de Genética, Universitat de Valencia, P O Box 2085, E 46071 Valencia, Spain
    J Mol Evol 55:127-37. 2002
    ..non-synonymous substitutions have been studied in partial sequences of the atpD and aroQ/pheA genes of primary ( Buchnera) and secondary symbionts of aphids and a set of selected non-symbiotic bacteria, belonging to the five ..
  78. pmc The process of genome shrinkage in the obligate symbiont Buchnera aphidicola
    N A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    Genome Biol 2:RESEARCH0054. 2001
    ..To examine the process of genome reduction, the tiny genome of the endosymbiont Buchnera aphidicola was compared to the larger ancestral genome, reconstructed on the basis of the phylogenetic ..
  79. ncbi An experimental validation of orphan genes of Buchnera, a symbiont of aphids
    Sayaka Shimomura
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Biochem Biophys Res Commun 292:263-7. 2002
    Although Buchnera sp. APS, an intracellular symbiont of pea aphids, is a close relative of Escherichia coli, its genome has been extensively modified because of its prolonged intracellular life...
  80. pmc Postsymbiotic plasmid acquisition and evolution of the repA1-replicon in Buchnera aphidicola
    R C van Ham
    Centro de Astrobiologia, Instituto Nacional de Técnica Aeroespacial, Edificio S 18, Carretera de Torrejón a Ajalvir, 28850 Torrejon de Ardoz, Spain
    Proc Natl Acad Sci U S A 97:10855-60. 2000
    b>Buchnera aphidicola is an obligate, strictly vertically transmitted, bacterial symbiont of aphids. It supplies its host with essential amino acids, nutrients required by aphids but deficient in their diet of plant phloem sap...
  81. pmc Decay of mutualistic potential in aphid endosymbionts through silencing of biosynthetic loci: Buchnera of Diuraphis
    J J Wernegreen
    Department of Ecology and Evolutionary Biology, Center for Insect Science, University of Arizona, Tucson 85721, USA
    Proc Biol Sci 267:1423-31. 2000
    b>Buchnera, the primary bacterial endosymbiont of aphids, is known to provision essential amino acids lacking in the hosts' diet of plant sap...
  82. pmc Prephenate dehydratase from the aphid endosymbiont (Buchnera) displays changes in the regulatory domain that suggest its desensitization to inhibition by phenylalanine
    N Jimenez
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva and Departament de Genètica, Universitat de Valencia, 46071 Valencia, Spain
    J Bacteriol 182:2967-9. 2000
    b>Buchnera aphidicola, the prokaryotic endosymbiont of aphids, complements dietary deficiencies with the synthesis and provision of several essential amino acids. We have cloned and sequenced a region of the genome of B...
  83. ncbi Sequence evolution in bacterial endosymbionts having extreme base compositions
    M A Clark
    Microbiology Section, University of California, Davis, USA
    Mol Biol Evol 16:1586-98. 1999
    ..Sequences for a functionally diverse set of genes have been obtained for bacterial endosymbionts (Buchnera) from two pairs of aphid host species, each pair diverging 50-70 MYA...
  84. ncbi Extraordinary proliferation of microorganisms in aposymbiotic pea aphids, Acyrthosiphon pisum
    Atsushi Nakabachi
    Molecular Microbial Ecology Division, Bioscience Technology Center, RIKEN, The Institute of Physical and Chemical Research, Hirosawa 2 1, Wako Shi, 351 0198, Saitama, Japan
    J Invertebr Pathol 82:152-61. 2003
    Aposymbiotic pea aphids, which were deprived of their intracellular symbiotic bacterium, Buchnera, exhibit growth retardation and no fecundity...
  85. pmc Mutational and selective pressures on codon and amino acid usage in Buchnera, endosymbiotic bacteria of aphids
    Claude Rispe
    UMR BiO3P, Institut National de la Recherche Agronomique, BP35327, 35653 Le Rheu Cedex, France
    Genome Res 14:44-53. 2004
    ..variation at synonymous (codon usage) and nonsynonymous (amino acid usage) positions in three complete genomes of Buchnera, endosymbiotic bacteria of aphids, and also in their orthologs in Escherichia coli, a close free-living relative...
  86. ncbi Why are the genomes of endosymbiotic bacteria so stable?
    Francisco J Silva
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva and Departament de Genètica, Universitat de Valencia, Apartado 22085, 46071 Valencia, Spain
    Trends Genet 19:176-80. 2003
    The comparative analysis of three strains of the endosymbiotic bacterium Buchnera aphidicola has revealed high genome stability associated with an almost complete absence of chromosomal rearrangements and horizontal gene transfer events ..
  87. pmc Fine-scale cospeciation between Brachycaudus and Buchnera aphidicola: bacterial genome helps define species and evolutionary relationships in aphids
    Emmanuelle Jousselin
    INRA, UMR CBGP INRA IRD Cirad Montpellier SupAgro, Campus International de Baillarguet, CS 30016, 34988 Montferrier sur Lez Cedex, France
    Proc Biol Sci 276:187-96. 2009
    Aphids harbour an obligatory symbiont, Buchnera aphidicola, providing essential amino acids not supplied by their diet...
  88. pmc A genomic perspective on nutrient provisioning by bacterial symbionts of insects
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 100:14543-8. 2003
    ..The best studied such association is that between aphids and Buchnera aphidicola, which produces essential amino acids that are rare in the phloem sap diet...
  89. pmc Developmental origin and evolution of bacteriocytes in the aphid-Buchnera symbiosis
    Christian Braendle
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, USA
    PLoS Biol 1:E21. 2003
    ..the development and evolution of aphid bacteriocytes, the host cells that contain the endosymbiotic bacteria Buchnera aphidicola...
  90. ncbi Comparative analysis of two genomic regions among four strains of Buchnera aphidicola, primary endosymbiont of aphids
    Vicente Perez-Brocal
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Apartado de Correos 22085, 46071 Valencia, Spain
    Gene 345:73-80. 2005
    Preliminary analysis of two selected genomic regions of Buchnera aphidicola BCc, the primary endosymbiont of the cedar aphid Cinara cedri, has revealed a number of interesting features when compared with the corresponding homologous ..
  91. ncbi Expression of host S-adenosylmethionine decarboxylase gene and polyamine composition in aphid bacteriocytes
    A Nakabachi
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo, Bunkyo ku, 113 0033, Tokyo, Japan
    Insect Biochem Mol Biol 31:491-6. 2001
    ..This is the first report of polyamine assessment in a prokaryote-eukaryote endocellular symbiotic system, which demonstrated a unique polyamine composition...
  92. ncbi Muller's ratchet in symbiont populations
    Mats E Pettersson
    Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, SE 75236, Uppsala, Sweden
    Genetica 130:199-211. 2007
    ....
  93. pmc Vertical transmission of biosynthetic plasmids in aphid endosymbionts (Buchnera)
    J J Wernegreen
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
    J Bacteriol 183:785-90. 2001
    This study tested for horizontal transfer of plasmids among Buchnera aphidicola strains associated with ecologically and phylogenetically related aphid hosts (Uroleucon species)...
  94. ncbi Evolution of minimal-gene-sets in host-dependent bacteria
    Lisa Klasson
    Department of Molecular Evolution, Evolutionary Biology Center, Uppsala University, Norbyvagen 18C, 752 36 Uppsala, Sweden
    Trends Microbiol 12:37-43. 2004
    ....
  95. ncbi Dynamics of reductive genome evolution in mitochondria and obligate intracellular microbes
    Amit N Khachane
    Department of Environmental Microbiology, Helmholtz Center for Infection Research, Braunschweig, Germany
    Mol Biol Evol 24:449-56. 2007
    ..predictions by comparison with estimated extents of genome reduction known to have occurred in mitochondria and Buchnera aphidicola, through comparative genomics and by drawing on available fossil evidences...
  96. ncbi Genetic evidence from mitochondrial, nuclear, and endosymbiont markers for the evolution of host plant associated species in the aphid genus Hyalopterus (Hemiptera: Aphididae)
    Jeffrey D Lozier
    Department of Environmental Science, Policy, and Management, 137 Mulford Hall, University of California, Berkeley, CA 94720 3114, USA
    Evolution 61:1353-67. 2007
    ..Using mitochondrial COI sequences, 16S rDNA sequences from the aphid endosymbiont Buchnera aphidicola, and nine microsatellite loci we investigated population structure in Hyalopterus from the most ..
  97. ncbi Mutualists and parasites: how to paint yourself into a (metabolic) corner
    I Tamas
    Department of Molecular Evolution, University of Uppsala, , S-752 36, Uppsala, Sweden
    FEBS Lett 498:135-9. 2001
    ..The genome sequences of the symbiotic bacteria of aphids, Buchnera aphidicola, and the parasitic bacteria of body louse and humans, Rickettsia prowazekii, provide insights into ..
  98. ncbi Molecular systematics of aphids and their primary endosymbionts
    D Martinez-Torres
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Valencia, Apartado de Correos 2085, 46071, Spain
    Mol Phylogenet Evol 20:437-49. 2001
    ..They exhibit a mutualistic association with intracellular bacteria (Buchnera sp.) related to Escherichia coli. Buchnera is usually considered the aphids' primary endosymbiont...
  99. ncbi Endosymbiosis: past and present
    M van der Giezen
    Heredity (Edinb) 95:335-6. 2005
  100. ncbi Antibiotics, primary symbionts and wing polyphenism in three aphid species
    Jim Hardie
    Imperial College London, Faculty of Natural Sciences, Division of Biology, Silwood Park Campus, Ascot, Berks SL5 7PY, UK
    Insect Biochem Mol Biol 37:886-90. 2007
    The possible role of the primary Buchnera symbionts in wing polyphenism is examined in three aphid species. Presumptive winged aphids were fed on antibiotic-treated beans to destroy these symbionts...
  101. ncbi A matter of fitness
    Ana Cerdeno-Tárraga
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
    Trends Microbiol 11:111-2. 2003

Research Grants2

  1. MECHANISMS AND CONSEQUENCES OF DELETERIOUS EVOLUTION IN BACTERIA
    Jennifer J Wernegreen; Fiscal Year: 2010
    ..By deciphering fundamental mechanisms that influence bacterial genome evolution, this study will contribute to a predictive framework for understanding how microbes evolve. ..
  2. The molecular basis of morphological evolution
    David L Stern; Fiscal Year: 2010
    ..This detailed analysis of gene regulation promises to provide new insights into how gene regulation functions and evolves in natural species to cause possibly adaptive changes in morphology. ..