Genomes and Genes
Summary: A bacterial genus of the order ACTINOMYCETALES.
Publications312 found, 100 shown here
- Two angular dioxygenases contribute to the metabolic versatility of dibenzofuran-degrading Rhodococcus sp. strain HA01Hamdy A H Aly
Department of Environmental Microbiology, HZI Helmholtz Centre for Infection Research, Inhoffenstrasse 7, D 38124 Braunschweig, Germany
Appl Environ Microbiol 74:3812-22. 2008b>Rhodococcus sp. strain HA01, isolated through its ability to utilize dibenzofuran (DBF) as the sole carbon and energy source, was also capable, albeit with low activity, of transforming dibenzo-p-dioxin (DD)...
- Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels developmentJason W Holder
Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
PLoS Genet 7:e1002219. 2011The Actinomycetales bacteria Rhodococcus opacus PD630 and Rhodococcus jostii RHA1 bioconvert a diverse range of organic substrates through lipid biosynthesis into large quantities of energy-rich triacylglycerols (TAGs)...
- Extracellular polysaccharides of Rhodococcus rhodochrous S-2 stimulate the degradation of aromatic components in crude oil by indigenous marine bacteriaNoriyuki Iwabuchi
Laboratory of Molecular Microbiology, Department of Applied Biological Science, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa 252 8510, Japan
Appl Environ Microbiol 68:2337-43. 2002b>Rhodococcus rhodochrous S-2 produces extracellular polysaccharides (S-2 EPS) containing D-glucose, D-galactose, D-mannose, D-glucuronic acid, and lipids, which is important to the tolerance of this strain to an aromatic fraction of (AF) ..
- A Rhodococcus qsdA-encoded enzyme defines a novel class of large-spectrum quorum-quenching lactonasesStephane Uroz
Interactions Plantes et Microorganismes de Rhizosphère, Institut des Sciences du Vegetal, CNRS, Avenue de Terrasse, 91198 Gif sur Yvette Cedex, France
Appl Environ Microbiol 74:1357-66. 2008..involved in N-acyl homoserine lactone (N-AHSL) degradation was identified by screening a genomic library of Rhodococcus erythropolis strain W2...
- A novel p-nitrophenol degradation gene cluster from a gram-positive bacterium, Rhodococcus opacus SAO101Wataru Kitagawa
Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305 8566, Japan
J Bacteriol 186:4894-902. 2004..In this study, a novel 4-NP degradation gene cluster from a gram-positive bacterium, Rhodococcus opacus SAO101, was identified and characterized...
- Gamma-caprolactone stimulates growth of quorum-quenching Rhodococcus populations in a large-scale hydroponic system for culturing Solanum tuberosumAmélie Cirou
Centre National de la Recherche Scientifique, Institut des Sciences du Vegetal, Gif sur Yvette, France
Res Microbiol 162:945-50. 2011..Post-GCL treatment, QS-degrading bacteria were mainly identified as Rhodococcus isolates, while Agrobacterium isolates dominated under similar untreated conditions...
- Functional expression system for cytochrome P450 genes using the reductase domain of self-sufficient P450RhF from Rhodococcus sp. NCIMB 9784Miho Nodate
Marine Biotechnology Institute, 3 75 1 Heita, Kamaishi, Iwate, 026 0001, Japan
Appl Microbiol Biotechnol 71:455-62. 2006Cytochrome P450RhF from Rhodococcus sp. NCIMB 9784 is a self-sufficient P450 monooxygenase...
- Biosynthesis of auxin by the gram-positive phytopathogen Rhodococcus fascians is controlled by compounds specific to infected plant tissuesOlivier Vandeputte
Laboratory of Plant Biotechnology, Universite Libre de Bruxelles, 1850 chaussée de Wavre, B 1160 Brussels, Belgium
Appl Environ Microbiol 71:1169-77. 2005..The phytopathogen Rhodococcus fascians, a gram-positive organism, incites diverse developmental alterations, such as leafy galls, on a wide ..
- Identification of DypB from Rhodococcus jostii RHA1 as a lignin peroxidaseMark Ahmad
Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK
Biochemistry 50:5096-107. 2011b>Rhodococcus jostii RHA1, a polychlorinated biphenyl-degrading soil bacterium whose genome has been sequenced, shows lignin degrading activity in two recently developed spectrophotometric assays...
- Mechanism of 4-nitrophenol oxidation in Rhodococcus sp. Strain PN1: characterization of the two-component 4-nitrophenol hydroxylase and regulation of its expressionMasahiro Takeo
Department of Materials Science and Chemistry, Graduate School of Engineering, University of Hyogo, 2167 Shosha, Himeji, Hyogo 671 2201, Japan
J Bacteriol 190:7367-74. 2008..b>Rhodococcus sp. strain PN1 degrades 4-NP via 4-nitrocatechol (4-NC) for use as the sole carbon, nitrogen, and energy source...
- N-acylhomoserine lactonase producing Rhodococcus spp. with different AHL-degrading activitiesSun Yang Park
Systems Microbiology Research Center, Korea Research Institute of Bioscience and Biotechnology KRIBB, Yuseung, Daejon, Korea
FEMS Microbiol Lett 261:102-8. 2006..Previously, Rhodococcus erythropolis W2 was reported to degrade AHLs by both oxido-reductase and AHL-acylase...
- Cloning and characterization of a gene involved in triacylglycerol biosynthesis and identification of additional homologous genes in the oleaginous bacterium Rhodococcus opacus PD630Adrian F Alvarez
Centro Regional de Investigación y Desarrollo Científico Tecnológico CRIDECIT, Facultad de Ciencias Naturales, Universidad Nacional de la Patagonia San Juan Bosco, Comodoro Rivadavia, Argentina
Microbiology 154:2327-35. 2008..To identify additional Atfs in strain PD630, PCR employing non-degenerate primers deduced from Rhodococcus jostii RHA1 sequence data was used...
- Characterization of dye-decolorizing peroxidases from Rhodococcus jostii RHA1Joseph N Roberts
Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
Biochemistry 50:5108-19. 2011The soil bacterium Rhodococcus jostii RHA1 contains two dye-decolorizing peroxidases (DyPs) named according to the subfamily they represent: DypA, predicted to be periplasmic, and DypB, implicated in lignin degradation...
- Differences of heterotrophic 13CO2 assimilation by Pseudomonas knackmussii strain B13 and Rhodococcus opacus 1CP and potential impact on biomarker stable isotope probingStefan Feisthauer
Department of Isotope Biogeochemistry, UFZ Helmholtz Centre for Environmental Research Leipzig, Permoserstrasse 15, D 04318 Leipzig, Germany
Environ Microbiol 10:1641-51. 2008Motivated by the finding that Pseudomonas knackmussii B13 but not Rhodococcus opacus 1CP grows in the absence of externally provided CO(2), we investigated the assimilation of (13)CO(2) into active cells cultivated with non-labelled ..
- Gene cloning and characterization of multiple alkane hydroxylase systems in Rhodococcus strains Q15 and NRRL B-16531L G Whyte
Biotechnology Research Institute, National Research Council of Canada, Montreal, Quebec, Canada H4P 2R2
Appl Environ Microbiol 68:5933-42. 2002The alkane hydroxylase systems of two Rhodococcus strains (NRRL B-16531 and Q15, isolated from different geographical locations) were characterized...
- Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active siteMichael Arand
Department of Toxicology, University of Wurzburg, Versbacher Strasse 9, D 97078 Wurzburg, Germany
EMBO J 22:2583-92. 2003..We report here the structure of the limonene-1,2-epoxide hydrolase from Rhodococcus erythropolis, solved using single-wavelength anomalous dispersion from a selenomethionine-substituted protein ..
- Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limoneneM J van der Werf
Division of Industrial Microbiology, Department of Food Technology and Nutritional Sciences, Wageningen University and Research Centre, Wageningen, The Netherlands
Appl Environ Microbiol 65:2092-102. 1999..This organism was identified as a strain of Rhodococcus erythropolis by chemotaxonomic and genetic studies. R...
- Functional characterization of a gene cluster involved in gentisate catabolism in Rhodococcus sp. strain NCIMB 12038Ting Ting Liu
CAS Key Laboratory of Agricultural and Environmental Microbiology, Wuhan Institute of Virology, Chinese Academy of Sciences CAS, Wuhan 430071, China
Appl Microbiol Biotechnol 90:671-8. 2011b>Rhodococcus sp. strain NCIMB 12038 utilizes naphthalene as a sole source of carbon and energy, and degrades naphthalene via salicylate and gentisate...
- Degradation of 4-nitrophenol, 2-chloro-4-nitrophenol, and 2,4-dinitrophenol by Rhodococcus imtechensis strain RKJ300Anuradha Ghosh
Institute of Microbial Technology, Chandigarh 160036, India
Environ Sci Technol 44:1069-77. 2010A bacterial strain Rhodococcus imtechensis RKJ300 (= MTCC 7085(T) = JCM 13270(T)) was isolated from pesticide-contaminated soil of Punjab by the enrichment technique on minimal medium containing 4-nitrophenol...
- The plasmid-located haloalkane dehalogenase gene from Rhodococcus rhodochrous NCIMB 13064A N Kulakova
Queen s University of Belfast, UK
Microbiology 143:109-15. 1997The haloalkane dehalogenase (dhaA) gene from Rhodococcus rhodochrous NCIMB 13064 was cloned and sequenced. Its comparison with the previously studied dhlA gene from Xanthobacter autotrophicus GJ10 did not show homology...
- Characterization of IS2112, a new insertion sequence from Rhodococcus, and its relationship with mobile elements belonging to the IS110 familyL A Kulakov
The Questor Centre, The Queen s University of Belfast, UK
Microbiology 145:561-8. 1999A new insertion sequence (IS2112) was identified in the genome of the 1-haloalkane-utilizing bacterium Rhodococcus rhodochrous NCIMB 13064...
- Members of the genera Paenibacillus and Rhodococcus harbor genes homologous to enterococcal glycopeptide resistance genes vanA and vanBL Guardabassi
Department of Veterinary Pathobiology, The Royal Veterinary and Agricultural University, Frederiksberg, Denmark
Antimicrob Agents Chemother 48:4915-8. 2004..enterococcal glycopeptide resistance genes vanA and vanB were found in glycopeptide-resistant Paenibacillus and Rhodococcus strains from soil...
- Catabolic pathway of gamma-caprolactone in the biocontrol agent Rhodococcus erythropolisCorinne Barbey
Laboratoire de Microbiologie Signaux et Microenvironnement, Normandie Université, EA 4312 Université de Rouen, IUT Evreux 55 rue Saint Germain, 27000 Evreux, France
J Proteome Res 11:206-16. 2012..Among these biocontrol agents, Rhodococcus erythropolis, characterized by a remarkable metabolic versatility, assimilates various γ-butyrolactone ..
- Efficient biostimulation of native and introduced quorum-quenching Rhodococcus erythropolis populations is revealed by a combination of analytical chemistry, microbiology, and pyrosequencingAmélie Cirou
Centre National de la Recherche Scientifique, Institut des Sciences du Vegetal, Gif sur Yvette, France
Appl Environ Microbiol 78:481-92. 2012..molecular approaches were combined to explore and compare biostimulation of native and introduced AHL-degrading Rhodococcus erythropolis populations in the rhizosphere of potato plants cultivated in farm greenhouses under hydroponic ..
- Biodegradation and Rhodococcus--masters of catabolic versatilityMichael J Larkin
School of Biology and Biochemistry and The QUESTOR Centre, The Queen s University of Belfast, Belfast BT9 5AG, Northern Ireland, UK
Curr Opin Biotechnol 16:282-90. 2005The genus Rhodococcus is a very diverse group of bacteria that possesses the ability to degrade a large number of organic compounds, including some of the most difficult compounds with regard to recalcitrance and toxicity...
- Global response to desiccation stress in the soil actinomycete Rhodococcus jostii RHA1Justin C LeBlanc
Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada
Appl Environ Microbiol 74:2627-36. 2008b>Rhodococcus jostii RHA1 is a soil-residing actinomycete with many favorable metabolic capabilities that make it an ideal candidate for the bioremediation of contaminated soils...
- Identification of a new class of cytochrome P450 from a Rhodococcus spGareth A Roberts
The Edinburgh Centre for Protein Technology, Department of Chemistry, University of Edinburgh, United Kingdom
J Bacteriol 184:3898-908. 2002A degenerate set of PCR primers were used to clone a gene encoding a cytochrome P450 (the P450RhF gene) from Rhodococcus sp. strain NCIMB 9784 which is of unique primary structural organization...
- A novel lipopeptide produced by a Pacific Ocean deep-sea bacterium, Rhodococcus sp. TW53F Peng
Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, State Oceanic Administration, Xiamen, Fujian, China
J Appl Microbiol 105:698-705. 2008..Our goal was to find a novel, biosurfactant-producing bacterium from Pacific Ocean deep-sea sediments...
- Crystal structure of the terminal oxygenase component of biphenyl dioxygenase derived from Rhodococcus sp. strain RHA1Yutaka Furusawa
Biological Information Research Center BIRC, National Institute of Advanced Industrial Science and Technology AIST, 2 41 6 Aomi, Koto ku, Tokyo 135 0064, Japan
J Mol Biol 342:1041-52. 2004..the crystal structure of the terminal oxygenase component of the biphenyl dioxygenase (BphA1A2) derived from Rhodococcus strain sp. RHA1 in substrate-free and complex forms...
- Crystal structures of cyclohexanone monooxygenase reveal complex domain movements and a sliding cofactorI Ahmad Mirza
Department of Biochemistry, McGill University, 3649 Prom Sir William Osler, Bellini Pavilion, Room 466, Montreal, QC, Canada H3G 0B1
J Am Chem Soc 131:8848-54. 2009..We present here the atomic structures of CHMO from an environmental Rhodococcus strain bound with FAD and NADP(+) in two distinct states, to resolutions of 2.3 and 2.2 A...
- Characteristics of styrene degradation by Rhodococcus pyridinovorans isolated from a biofilterIn Gyung Jung
Industrial Liaison Research Institute, Kyung Hee University, Yongin 449 701, South Korea
Chemosphere 61:451-6. 2005A novel strain (PYJ-1) of Rhodococcus pyridinovorans that was isolated from a biofilter was able to degrade styrene at a maximum rate of 0.16 mg (mg protein)(-1) h(-1) in batch culture at 97 mg l(-1) of initial styrene gas concentration...
- Biosynthesis of storage compounds by Rhodococcus jostii RHA1 and global identification of genes involved in their metabolismMartín A Hernández
Centro Regional de Investigación y Desarrollo Científico Tecnológico, Facultad de Ciencias Naturales, Universidad Nacional de Patagonia San Juan Bosco, Km 4 Ciudad Universitaria, 9000 Comodoro Rivadavia, Chubut, Argentina
BMC Genomics 9:600. 2008Members of the genus Rhodococcus are frequently found in soil and other natural environments and are highly resistant to stresses common in those environments...
- Virulence quenching with a prenylated isoflavanone renders the Malagasy legume Dalbergia pervillei resistant to Rhodococcus fasciansSanda Rajaonson
Laboratoire de Biotechnologie Végétale, Universite Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, Gosselies, Belgium
Environ Microbiol 13:1236-52. 2011The phytopathogenic Actinomycete Rhodococcus fascians induces leafy galls on a wide range of hosts, causing major economical losses in the ornamentals industry...
- Identification of the major functional proteins of prokaryotic lipid dropletsYunfeng Ding
National Laboratory of Biomacromolecules, Institute of Biophysics, Beijing, China
J Lipid Res 53:399-411. 2012..We obtained highly purified LDs from Rhodococcus sp...
- Biphenyl and ethylbenzene dioxygenases of Rhodococcus jostii RHA1 transform PBDEsKristin R Robrock
Department of Civil and Environmental Engineering, University of California, Berkeley, USA
Biotechnol Bioeng 108:313-21. 2011..Resting cells of the polychlorinated biphenyl-degrading actinomycete, Rhodococcus jostii RHA1, depleted nine mono- through penta-BDEs in separate assays...
- Rhodococcus qingshengii sp. nov., a carbendazim-degrading bacteriumJing Liang Xu
Key Laboratory for Microbiological Engineering of Agricultural Environment of Ministry of Agriculture, Nanjing Agricultural University, Nanjing 210095, People s Republic of China
Int J Syst Evol Microbiol 57:2754-7. 2007..mycolic acids showed that the characteristics of strain djl-6(T) were in good agreement with those of the genus Rhodococcus. DNA-DNA hybridization showed that it had low genomic relatedness with Rhodococcus baikonurensis DSM 44587(T) (..
- Analysis of aflatoxin-B1-degrading microbes by use of a combined toxicity-profiling methodCsilla Krifaton
Department of Environmental Protection and Safety, Szent Istvan University, Godollo, Hungary
Mutat Res 726:1-7. 2011..Among thirty-three isolates, the strain Rhodococcus rhodochrous NI2 proved to be the best aflatoxin-B1-degrading microbe, with the weakest harmful biological ..
- Biocatalytic asymmetric hydrogen transfer employing Rhodococcus ruber DSM 44541Wolfgang Stampfer
Department of Chemistry, Organic and Bioorganic Chemistry, University of Graz, Heinrichstrasse 28, Austria
J Org Chem 68:402-6. 2003..kinetic resolution of the rac-alcohol using acetone as hydrogen acceptor employing whole lyophilized cells of Rhodococcus ruber DSM 44541...
- The first characterization of a eubacterial proteasome: the 20S complex of RhodococcusT Tamura
Max Planck Institute for Biochemistry, Martinsried, Germany
Curr Biol 5:766-74. 1995....
- Discovery and characterization of a putrescine oxidase from Rhodococcus erythropolis NCIMB 11540Erik W van Hellemond
Laboratory of Biochemistry, University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute, Nijenborgh 4, 9747 AG, Groningen, The Netherlands
Appl Microbiol Biotechnol 78:455-63. 2008A gene encoding a putrescine oxidase (PuORh, EC 22.214.171.124) was identified from the genome of Rhodococcus erythropolis NCIMB 11540. The gene was cloned in the pBAD vector and overexpressed at high levels in Escherichia coli...
- Rhodococcus sp. RB1 grows in the presence of high nitrate and nitrite concentrations and assimilates nitrate in moderately saline environmentsR Blasco
, Facultad de Ciencias, , Spain
Arch Microbiol 175:435-40. 2001b>Rhodococcus sp. RB1 was able to thrive in media with up to 0.9 M NaCl or KCl and in the presence of high concentrations of nitrate (up to 0.9 M) and nitrite (up to 60 mM), but only under oxic conditions...
- Limonene-1,2-epoxide hydrolase from Rhodococcus erythropolis DCL14 belongs to a novel class of epoxide hydrolasesM J van der Werf
Division of Industrial Microbiology, Department of Food Technology and Nutritional Sciences, Wageningen Agricultural University, 6700 EV Wageningen, The Netherlands
J Bacteriol 180:5052-7. 1998An epoxide hydrolase from Rhodococcus erythropolis DCL14 catalyzes the hydrolysis of limonene-1,2-epoxide to limonene-1,2-diol. The enzyme is induced when R...
- Functional annotation and characterization of 3-hydroxybenzoate 6-hydroxylase from Rhodococcus jostii RHA1Stefania Montersino
Wageningen University, Wageningen, The Netherlands
Biochim Biophys Acta 1824:433-42. 2012The genome of Rhodococcus jostii RHA1 contains an unusually large number of oxygenase encoding genes...
- Potential of Rhodococcus strains for biotechnological vanillin production from ferulic acid and eugenolRainer Plaggenborg
Institut für Molekulare Mikrobiologie und Biotechnologie der Westfälischen Wilhelms Universität Münster, Corrensstr 3, 48149 Munster, Germany
Appl Microbiol Biotechnol 72:745-55. 2006The potential of two Rhodococcus strains for biotechnological vanillin production from ferulic acid and eugenol was investigated. Genome sequence data of Rhodococcus sp...
- Rhodococcus nanhaiensis sp. nov., an actinobacterium isolated from marine sedimentJie Li
Key Laboratory of Marine Bio resources Sustainable Utilization CAS, RNAM Center for Marine Microbiology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, PR China
Int J Syst Evol Microbiol 62:2517-21. 2012..0). Based on 16S rRNA gene sequence analysis, the strains were identified as members of the genus Rhodococcus. Phylogenetic analysis showed that the two strains clustered together and the 16S rRNA gene sequence ..
- Cell surface hydrophobicity and mycolic acid composition of Rhodococcus strains isolated from activated sludge foamH M Stratton
School of Environmental Sciences, Griffith University, Brisbane, Queensland 4111, Australia
J Ind Microbiol Biotechnol 28:264-7. 2002..between cell surface hydrophobicity (CSH), as determined by microbial adherence to hydrocarbons, of three Rhodococcus spp. isolated from activated sludge foam and their ability to produce a stable foam...
- Specificity of catechol ortho-cleavage during para-toluate degradation by Rhodococcus opacus 1cpM M Suvorova
Pushchino State University, Pushchino, Moscow Region, 142290, Russia
Biochemistry (Mosc) 71:1316-23. 2006Degradation of para-toluate by Rhodococcus opacus 1cp was investigated. Activities of the key enzymes of this process, catechol 1,2-dioxygenase and muconate cycloisomerase, are detected in this microorganism...
- Rhodococcus rhodochrous DSM 43269 3-ketosteroid 9alpha-hydroxylase, a two-component iron-sulfur-containing monooxygenase with subtle steroid substrate specificityM Petrusma
Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands
Appl Environ Microbiol 75:5300-7. 2009..KSH of Rhodococcus rhodochrous DSM 43269, consisting of a ferredoxin reductase (KshB) and a terminal oxygenase (KshA), was ..
- Insights into sequence-activity relationships amongst Baeyer-Villiger monooxygenases as revealed by the intragenomic complement of enzymes from Rhodococcus jostii RHA1Claudia Szolkowy
York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5YW, UK
Chembiochem 10:1208-17. 2009..The recently sequenced genome of Rhodococcus jostii RHA1, for example, has revealed an impressive array of catabolic enzymes, including many putative Baeyer-..
- Identification of Rhodococcus equi using the polymerase chain reactionK S Bell
Department of Biological Sciences, Napier University, Edinburgh, UK
Lett Appl Microbiol 23:72-4. 1996Two regions in the gene coding for 16S rRNA in Rhodococcus equi were selected as species-specific primer sequences for the polymerase chain reaction (PCR). PCR using these primers was tested against 10 strains of R...
- Degradation of a mixture of hydrocarbons, gasoline, and diesel oil additives by Rhodococcus aetherivorans and Rhodococcus wratislaviensisMarc Auffret
IFP, 1 4 Avenue de Bois Preau, F 92852 Rueil Malmaison, France
Appl Environ Microbiol 75:7774-82. 2009Two strains, identified as Rhodococcus wratislaviensis IFP 2016 and Rhodococcus aetherivorans IFP 2017, were isolated from a microbial consortium that degraded 15 petroleum compounds or additives when provided in a mixture containing 16 ..
- Hemolytic activity of a bacterial trehalose lipid biosurfactant produced by Rhodococcus sp.: evidence for a colloid-osmotic mechanismAna Zaragoza
Departamento de Bioquimica y Biologia Molecular A, Facultad de Veterinaria, Universidad de Murcia, E 30100 Murcia, Spain
Langmuir 26:8567-72. 2010A succinoyl trehalose lipid produced by Rhodococcus sp. behaves as a biological surfactant and also displays various interesting biological activities...
- QcrCAB operon of a nocardia-form actinomycete Rhodococcus rhodochrous encodes cytochrome reductase complex with diheme cytochrome cc subunitNobuhito Sone
Department of Biochemical Engineering and Science, Kyushu Institute of Technology, Kawazu 680 4, Iizuka, Fukuoka ken 820 8502, Japan
Biochim Biophys Acta 1557:125-31. 2003..genes encoding quinol-cytochrome c reductase (QcR) were cloned and sequenced from nocardia-form actinomycete Rhodococcus rhodochrous...
- Construction of Escherichia coli-Arthrobacter-Rhodococcus shuttle vectors based on a cryptic plasmid from Arthrobacter rhombi and investigation of their application for functional screeningRuta Stanislauskiene
Department of Molecular Microbiology and Biotechnology, Institute of Biochemistry, Vilnius University, Vilnius, Lithuania
FEMS Microbiol Lett 327:78-86. 2012..All vectors successfully replicated in Escherichia coli, Arthrobacter and Rhodococcus spp...
- Gene cloning and nucleotide sequencing and properties of a cocaine esterase from Rhodococcus sp. strain MB1M M Bresler
Institute of Biotechnology, University of Cambridge, Cambridge CB2 1QT, United Kingdom
Appl Environ Microbiol 66:904-8. 2000A strain of Rhodococcus designated MB1, which was capable of utilizing cocaine as a sole source of carbon and nitrogen for growth, was isolated from rhizosphere soil of the tropane alkaloid-producing plant Erythroxylum coca...
- Functional characterization of a catabolic plasmid from polychlorinated- biphenyl-degrading Rhodococcus sp. strain RHA1Rene Warren
Genome Sciences Centre, Vancouver, Canada
J Bacteriol 186:7783-95. 2004b>Rhodococcus sp. strain RHA1, a potent polychlorinated-biphenyl (PCB)-degrading strain, contains three linear plasmids ranging in size from 330 to 1,100 kb...
- Recovery of Rhodococcus biosurfactants using methyl tertiary-butyl ether extractionM S Kuyukina
Institute of Ecology and Genetics of Microorganisms, Ural Branch of Russian Academy of Sciences, 12 Golev Street, 614081, Perm, Russia
J Microbiol Methods 46:149-56. 2001..study, we proposed methyl tertiary-butyl ether (MTBE) as a solvent for extraction of biosurfactants from Rhodococcus bacterial cultures...
- The remarkable Rhodococcus erythropolisCarla C C R de Carvalho
Centro de Engenharia Biologica e Quimica, Instituto Superior Tecnico, Av Rovisco Pais, Lisboa, 1049 001, Portugal
Appl Microbiol Biotechnol 67:715-26. 2005b>Rhodococcus erythropolis cells contain a large set of enzymes that allow them to carry out an enormous number of bioconversions and degradations...
- Benzothiazole degradation by Rhodococcus pyridinovorans strain PA: evidence of a catechol 1,2-dioxygenase activityNicolas Haroune
Laboratoire de Synthèse et Etude de Systèmes à Intérêt Biologique, UMR 6504 CNRS Université Blaise Pascal, 63177 Aubiere Cedex, France
Appl Environ Microbiol 68:6114-20. 2002The pathway for biodegradation of benzothiazole (BT) and 2-hydroxybenzothiazole (OBT) by Rhodococcus pyridinovorans strain PA was studied in detail...
- Post-translational modification of Rhodococcus R312 and Comamonas NI1 nitrile hydratasesJulie M Stevens
Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques UMR 8601 CNRS, Universite Rene Descartes Paris V, 45 Rue des Saints Peres, 75270 Paris Cedex 06, France
J Mass Spectrom 38:955-61. 2003..cysteines in the iron coordination spheres of two iron-containing nitrile hydratases, namely R312 NHase from Rhodococcus rhodochrous strain R312 and NI1 NHase from Comamonas testosteroni...
- Genome sequence of Rhodococcus erythropolis XP, a biodesulfurizing bacterium with industrial potentialFei Tao
State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai 200240, People s Republic of China
J Bacteriol 193:6422-3. 2011b>Rhodococcus erythropolis strains have shown excellent characteristics in petroleum oil biodesulfurization. Here we present the first announcement of the draft genome sequence of an efficient biodesulfurizing bacterium named R...
- Identification of a novel self-sufficient styrene monooxygenase from Rhodococcus opacus 1CPDirk Tischler
Environmental Microbiology, TU Bergakademie Freiberg, Freiberg, Germany
J Bacteriol 191:4996-5009. 2009Sequence analysis of a 9-kb genomic fragment of the actinobacterium Rhodococcus opacus 1CP led to identification of an open reading frame encoding a novel fusion protein, StyA2B, with a putative function in styrene metabolism via styrene ..
- Characterization of ARC, a divergent member of the AAA ATPase family from Rhodococcus erythropolisS Wolf
Max Planck Institut fur Biochemie, Am Klopferspitz 18a, Martinsried, D 82152, Germany
J Mol Biol 277:13-25. 1998..discovered in the 5' region of the second operon of 20 S proteasome subunits in the nocardioform actinomycete Rhodococcus erythropolis NI86/21. The gene was cloned and expressed in Escherichia coli...
- Construction of Rhodococcus random mutagenesis libraries using Tn5 transposition complexesP J Fernandes
Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK
Microbiology 147:2529-36. 2001The ability to generate tagged mutants of Rhodococcus spp. will facilitate a deeper understanding of this medically and commercially important genus...
- Improved identification of Gordonia, Rhodococcus and Tsukamurella species by 5'-end 16S rRNA gene sequencingTao Wang
Department of Neurosurgery, Beijing Tian Tan Hospital, Capital Medical University, Beijing, PR China
Pathology 43:58-63. 2011The identification of fastidious aerobic Actinomycetes such as Gordonia, Rhodococcus, and Tsukamurella has remained a challenge leading to clinically significant misclassifications...
- Cloning and characterization of an amidase gene from Rhodococcus species N-774 and its expression in Escherichia coliY Hashimoto
Department of Agricultural Chemistry, University of Tokyo, Japan
Biochim Biophys Acta 1088:225-33. 1991..of an unknown open reading frame which is present upstream of the nitrile hydratase (NHase) gene from Rhodococcus sp. N-774, a longer DNA fragment covering the entire gene was cloned in Escherichia coli...
- Deep desulfurization of diesel oil and crude oils by a newly isolated Rhodococcus erythropolis strainBo Yu
State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, People s Republic of China
Appl Environ Microbiol 72:54-8. 2006The soil-isolated strain XP was identified as Rhodococcus erythropolis. R. erythropolis XP could efficiently desulfurize benzonaphthothiophene, a complicated model sulfur compound that exists in crude oil...
- Identification of Rhodococcus fascians cytokinins and their modus operandi to reshape the plantIne Pertry
Department of Plant Systems Biology, Flanders Institute for Biotechnology, Technologiepark 927, 9052 Gent, Belgium
Proc Natl Acad Sci U S A 106:929-34. 2009Decades ago, the importance of cytokinins (CKs) during Rhodococcus fascians pathology had been acknowledged, and an isopentenyltransferase gene had been characterized in the fas operon of the linear virulence plasmid, but hitherto, no ..
- Elucidation of the metabolic pathway for dibenzothiophene desulphurization by Rhodococcus sp. strain IGTS8 (ATCC 53968)C Oldfield
Energy BioSystems Corporation, The Woodlands, TX 77381, USA
Microbiology 143:2961-73. 1997b>Rhodococcus sp. strain IGTS8 (ATCC 53968) is able to utilize dibenzothiophene (DBT) as a sole source of sulphur. The carbon skeleton of DBT is not metabolized and is conserved as 2-hydroxybiphenyl (HBP), which accumulates in the medium...
- Use of response surface optimization for the production of biosurfactant from Rhodococcus spp. MTCC 2574Snehal R Mutalik
Biochemical Engineering Department, Chemical Engineering and Process Development Division, National Chemical Laboratory, Pune 411008, India
Bioresour Technol 99:7875-80. 2008The production of biosurfactant from Rhodococcus spp. MTCC 2574 was effectively enhanced by response surface methodology (RSM). Rhodococcus spp. MTCC 2574 was selected through screening of seven different Rhodococcus strains...
- Sequence and molecular characterization of a DNA region encoding the dibenzothiophene desulfurization operon of Rhodococcus sp. strain IGTS8C S Piddington
Panlabs, Inc, Bothell, Washington 98011, USA
Appl Environ Microbiol 61:468-75. 1995..sulfur-containing organic molecules found in fossil fuels, can be desulfurized to 2-hydroxybiphenyl (2-HBP) by Rhodococcus sp. strain IGTS8. Complementation of a desulfurization (dsz) mutant provided the genes from Rhodococcus sp...
- Characterization of the desulfurization genes from Rhodococcus sp. strain IGTS8S A Denome
Department of Microbiology and Immunology, University of North Dakota School of Medicine, Grand Forks 58202
J Bacteriol 176:6707-16. 1994b>Rhodococcus sp. strain IGTS8 possesses an enzymatic pathway that can remove covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. The DNA sequence of a 4...
- Requirement of duplicated operons for maximal metabolism of phthalate by Rhodococcus sp. strain DK17Ki Young Choi
Department of Biology, Yonsei University, Seoul 120 749, Republic of Korea
Biochem Biophys Res Commun 357:766-71. 2007..protocatechuate are duplicated and present on two different megaplasmids [pDK2 (330 kb) and pDK3 (750 kb)] in Rhodococcus sp. strain DK17...
- Biodesulfurization of benzothiophene and dibenzothiophene by a newly isolated Rhodococcus strainY Tanaka
Microbial Community Analysis and Application Research Group, Research Institute of Biological Resources, National Institute of Advanced Industrial Science and Technology, Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
Appl Microbiol Biotechnol 59:325-8. 2002b>Rhodococcus sp. KT462, which can grow on either benzothiophene (BT) or dibenzothiophene (DBT) as the sole source of sulfur, was newly isolated and characterized...
- First case of bloodstream infection caused by Rhodococcus erythropolisHisashi Baba
Department of Infectious Disease, Nagoya University Hospital, Showa Ku, Japan
J Clin Microbiol 47:2667-9. 2009We describe the first case of bloodstream infection caused by Rhodococcus erythropolis. The identification was performed using 16S rRNA sequencing...
- Rhodostreptomycins, antibiotics biosynthesized following horizontal gene transfer from Streptomyces padanus to Rhodococcus fasciansKazuhiko Kurosawa
Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
J Am Chem Soc 130:1126-7. 2008
- Structural insights into substrate specificity and solvent tolerance in alcohol dehydrogenase ADH-'A' from Rhodococcus ruber DSM 44541Martin Karabec
Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50 3, A 8010 Graz, Austria
Chem Commun (Camb) 46:6314-6. 2010The structure of the alcohol dehydrogenase ADH-'A' from Rhodococcus ruber reveals possible reasons for its remarkable tolerance to organic co-solvents and suggests new directions for structure-informed mutagenesis to produce enzymes of ..
- Fly-attracting volatiles produced by Rhodococcus fascians and Mycobacterium aurum isolated from myiatic lesions of sheepJamal M Khoga
Department of Microbiology, Eotvos Lorand University, Múzeum krt 4 A, 1088 Budapest, Hungary
J Microbiol Methods 48:281-7. 2002..Strains identified as Rhodococcus fascians and Mycobacterium aurum produced various volatile sulfur compounds and benzene, and proved to be the ..
- Isolation and characterization of an atrazine-degrading Rhodococcus sp. strain MB-P1 from contaminated soil- Fazlurrahman
Institute of Microbial Technology, Chandigarh, India
Lett Appl Microbiol 49:721-9. 2009..The aim of this study is to isolate and characterize organisms capable of utilizing high concentration atrazine from the contaminated sites...
- Biodesulfurization of dibenzothiophene by a newly isolated Rhodococcus erythropolis strainFatemeh Davoodi-Dehaghani
Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
Bioresour Technol 101:1102-5. 2010..The strain, identified as Rhodococcus erythropolis SHT87, can utilize DBT, dibenzothiophene sulfone, thiophene, 2-methylthiophene and ..
- Genetic analysis around aminoalcohol dehydrogenase gene of Rhodococcus erythropolis MAK154: a putative GntR transcription factor in transcriptional regulationNobuyuki Urano
Kyoto University, Sakyo ku, Japan
Appl Microbiol Biotechnol 89:739-46. 2011NADP(+)-dependent aminoalcohol dehydrogenase (AADH) of Rhodococcus erythropolis MAK154 catalyzes the reduction of (S)-1-phenyl-1-keto-2-methylaminopropane ((S)-MAK) to d-pseudoephedrine, which is used as a pharmaceutical...
- Transcriptomic assessment of isozymes in the biphenyl pathway of Rhodococcus sp. strain RHA1Edmilson R Gonçalves
Department of Microbiology and Immunology, University of British Columbia, 1516 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada
Appl Environ Microbiol 72:6183-93. 2006b>Rhodococcus sp. RHA1 grows on a broad range of aromatic compounds and vigorously degrades polychlorinated biphenyls (PCBs)...
- 7-ketocholesterol catabolism by Rhodococcus jostii RHA1Jacques M Mathieu
Department of Civil and Environmental Engineering, Rice University, Houston, TX, USA
Appl Environ Microbiol 76:352-5. 2010..Microarrays were used to study mineralization of the most common oxysterol, 7-ketocholesterol (7KC), by Rhodococcus jostii RHA1...
- Analysis of catRABC operon for catechol degradation from phenol-degrading Rhodococcus erythropolisM Vesely
Institute of Microbiology, Academy of Sciences of the Czech Republic, v v i, Videnska 1083, 14220, Prague 4, Czech Republic
Appl Microbiol Biotechnol 76:159-68. 2007The gene cluster catRABC, involved in catechol degradation, was isolated from Rhodococcus erythropolis CCM2595...
- A novel NADP+-dependent L-1-amino-2-propanol dehydrogenase from Rhodococcus erythropolis MAK154: a promising enzyme for the production of double chiral aminoalcoholsM Kataoka
Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo ku, Kyoto, Japan
Lett Appl Microbiol 43:430-5. 2006A novel NADP(+)-dependent L-1-amino-2-propanol dehydrogenase was isolated from Rhodococcus erythropolis MAK154, and characterized.
- Identification and structural characterisation of novel trehalose dinocardiomycolates from n-alkane-grown Rhodococcus opacus 1CPSusanne Niescher
TU Bergakademie Freiberg, IOZ, 09596 Freiberg, Germany
Appl Microbiol Biotechnol 70:605-11. 2006b>Rhodococcus opacus 1CP, a potent degrader of (chloro-) aromatic compounds was found to utilise C10-C16 n-alkanes as sole carbon sources...
- Applicability of the functional gene catechol 1,2-dioxygenase as a biomarker in the detection of BTEX-degrading Rhodococcus speciesA Táncsics
Department of Microbiology, Eotvos Lorand University, Budapest, Hungary
J Appl Microbiol 105:1026-33. 2008..The detection of this gene is in focus today but recently designed degenerate primers are not always suitable. Rhodococcus species are important members of the bacterial community involved in the degradation of aromatic contaminants ..
- Degradation of alkanes and highly chlorinated benzenes, and production of biosurfactants, by a psychrophilic Rhodococcus sp. and genetic characterization of its chlorobenzene dioxygenasePeter Rapp
GBF National Research Centre for Biotechnology, Division of Microbiology, Mascheroderweg 1, D 38124 Braunschweig, Germany
Microbiology 149:2879-90. 2003b>Rhodococcus sp. strain MS11 was isolated from a mixed culture. It displays a diverse range of metabolic capabilities...
- Rothia aeria sp. nov., Rhodococcus baikonurensis sp. nov. and Arthrobacter russicus sp. nov., isolated from air in the Russian space laboratory MirYing Li
Department of Microbiology Bioinformatics, Regeneration and Advanced Medical Science, Gifu University, Graduate School of Medicine, Tsukasa machi 40, Gifu 500 8705, Japan
Int J Syst Evol Microbiol 54:827-35. 2004..of the bacteria based on their 16S rDNA sequence showed that they belong to the genera Rothia (A1-17B(T)), Rhodococcus (A1-22(T)) and Arthrobacter (A1-3(T) and A1-8)...
- pB264, a small, mobilizable, temperature sensitive plasmid from RhodococcusPhilip A Lessard
Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, USA
BMC Microbiol 4:15. 2004Gram-positive bacteria of the genus Rhodococcus have shown an extraordinary capacity for metabolizing recalcitrant organic compounds...
- Transcriptional response of Rhodococcus aetherivorans I24 to polychlorinated biphenyl-contaminated sedimentsEdoardo Puglisi
Istituto di Chimica Agraria ed Ambientale, Universita Cattolica del Sacro Cuore, Piacenza, Italy
Microb Ecol 60:505-15. 2010We used a microarray targeting 3,524 genes to assess the transcriptional response of the actinomycete Rhodococcus aetherivorans I24 in minimal medium supplemented with various substrates (e.g...
- Cytochrome P450 125 (CYP125) catalyses C26-hydroxylation to initiate sterol side-chain degradation in Rhodococcus jostii RHA1Kamila Z Rosłoniec
Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute GBB, University of Groningen, PO Box 14, 9750 AA Haren, The Netherlands
Mol Microbiol 74:1031-43. 2009The cyp125 gene of Rhodococcus jostii RHA1 was previously found to be highly upregulated during growth on cholesterol and the orthologue in Mycobacterium tuberculosis (rv3545c) has been implicated in pathogenesis...
- Rhodococcus baikonurensis BTM4c, a boron-tolerant actinobacterial strain isolated from soilJaewoo Yoon
Institute of Molecular and Cellular Biosciences, The University of Tokyo, Japan
Biosci Biotechnol Biochem 74:178-81. 2010..Molecular phylogenetic, chemotaxonomic, and physiological data showed that the strain belongs to the genus Rhodococcus, and is to be identified as Rhodococcus baikonurensis.
- Multiple respiratory bursts as a response to veratrate stress in Rhodococcus erythropolis cellsE Malarczyk
Department of Biochemistry, Maria Curie Sklodowska University, Maria Curie Sklodowska Square 3, Lublin, 20 031, Poland
Cell Biol Int 24:515-27. 2000Although Rhodococcus spp...
- Characterization of the 450-kb linear plasmid in a polychlorinated biphenyl degrader, Rhodococcus sp. strain RHA1S Shimizu
Department of Bioengineering, Nagaoka University of Technology, Kamitomioka, Nagaoka, Niigata 940-2188, Japan
Appl Environ Microbiol 67:2021-8. 2001A strong polychlorinated biphenyl (PCB) degrader, Rhodococcus sp. strain RHA1, has diverse biphenyl/PCB degradative genes and harbors huge linear plasmids, including pRHL1 (1,100 kb), pRHL2 (450 kb), and pRHL3 (330 kb)...
- Flux-based analysis of sulfur metabolism in desulfurizing strains of Rhodococcus erythropolisShilpi Aggarwal
Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore
FEMS Microbiol Lett 315:115-21. 2011b>Rhodococcus erythropolis has been studied widely for potential applications in biodesulfurization...
- Selective transport and accumulation of alkanes by Rhodococcus erythropolis S+14HeIn Seon Kim
Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Alberta T6G 2G6, Canada
Biotechnol Bioeng 80:650-9. 2002Selective transport and accumulation of n-alkanes by Rhodococcus erythropolis S+14He was studied by growing cells on n-hexadecane, n-octadecane or the branched alkane pristane, and on mixtures of hydrocarbons...
- Biotransformation of amides to acids using a co-cross-linked enzyme aggregate of Rhodococcus erythropolis amidaseHyun Joo Park
Division of Biotechnology, The Catholic University of Korea, Bucheon 420 743, Korea
J Microbiol Biotechnol 20:325-31. 2010b>Rhodococcus erythropolis amidase was expressed in Escherichia coli cells. The crude amidase in the cell-free extract was immobilized using the cross-linked enzyme aggregate (CLEA) method...
- Primary structure of an aliphatic nitrile-degrading enzyme, aliphatic nitrilase, from Rhodococcus rhodochrous K22 and expression of its gene and identification of its active site residueM Kobayashi
Department of Agricultural Chemistry, Faculty of Agriculture, Kyoto University, Japan
Biochemistry 31:9000-7. 1992Peptides obtained by cleavage of a Rhodococcus rhodochrous K22 nitrilase, which acts on aliphatic nitriles such as acrylonitrile, crotonitrile, and glutaronitrile, have been sequenced...
- The Rhodococcus opacus PD630 heparin-binding hemagglutinin homolog TadA mediates lipid body formationDaniel P Maceachran
Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Appl Environ Microbiol 76:7217-25. 2010Generally, prokaryotes store carbon as polyhydroxyalkanoate, starch, or glycogen. The Gram-positive actinomycete Rhodococcus opacus strain PD630 is noteworthy in that it stores carbon in the form of triacylglycerol (TAG)...
- Stereoselective carveol dehydrogenase from Rhodococcus erythropolis DCL14. A novel nicotinoprotein belonging to the short chain dehydrogenase/reductase superfamilyM J van der Werf
Division of Industrial Microbiology, Department of Food Technology and Nutritional Sciences, Wageningen University, Bomenweg 2, 6703 HD Wageningen, The Netherlands
J Biol Chem 274:26296-304. 1999..the dichlorophenolindophenol-dependent oxidation of carveol to carvone, was purified to homogeneity from Rhodococcus erythropolis DCL14. The enzyme is specifically induced after growth on limonene and carveol...
- Evaluation in Primates of Cocaine Esterase for the Treatment of Cocaine ToxicityMei Chuan Ko; Fiscal Year: 2010DESCRIPTION (provided by applicant): Cocaine esterase (CocE) is a product of the bacterium Rhodococcus sp. which grows in the rhizospheres of coca plants in South America...
- Pulmonary innate immunity and pathogens of the order ActinomycetalesTracy K Carlson; Fiscal Year: 2012..the outcome of disease particularly for bacteria of the order Actinomycetales, such as Mycobacteria and Rhodococcus spp., which have the ability to live in innate immune cells (alveolar macrophages)...
- T. cruzi molecular targets for vector paratransgenesisRavi V Durvasula; Fiscal Year: 2010..A paratransgenic strategy is being developed as an adjunctive approach. Rhodococcus rhodnii, the symbiont of Rhodnius prolixus, has been transformed to express cecropin A, an anti-trypanosomal ..
- A STRATEGY FOR SPREADING GENES IN CHAGAS DISEASE VECTORSRavi Durvasula; Fiscal Year: 2004..The symbiotic bacterium, Rhodococcus rhodnii, that resides in the reduviid vector, Rhodnius prolixus, has been transformed to export peptides toxic ..
- Structure Function Studies on Non-Heme Iron OxygenasesRamaswamy Subramanian; Fiscal Year: 2006..strain JS42 and naphthalene dioxygenase from Rhodococcus sp...
- Cytotoxic T Lymphocytes in immunity to Rhodococcus equiKRISTIN HASEL; Fiscal Year: 2003..state-of-the-art research involving equine cytotoxic T lymphocytes (CTLs) and pulmonary immunology of Rhodococcus equi, as well as the training of PhD candidates...
- Virulence of the Opportunistic Pathogen Rhodococcis EquiMARY HONDALUS; Fiscal Year: 2010..in individuals undergoing chemotherapy for various cancers, the understudied zoonotic opportunistic pathogen Rhodococcus equi has emerged as cause of life- threatening pneumonia in persons of compromised immunity...
- Development of Esterases for the Treatment of Cocaine Overdose and AbuseJames Woods; Fiscal Year: 2009DESCRIPTION (provided by applicant): Cocaine esterase (CocE) is a product of the bacterium Rhodococcus sp. which grows in the rhizosphere of coca plants in South America...
- CHOLESTEROL OXIDASE LOOP RESIDUES AND CATALYSISNicole Sampson; Fiscal Year: 2009..evidence suggests that cholesterol oxidase may be involved in the pathogenesis of some microorganisms such as Rhodococcus equi and Mycobacterium tuberculosis...
- An Inducible Expression System for M. tuberculosisRobert Husson; Fiscal Year: 2006..small grant application is to adapt an inducible expression system, the positively regulated nitA promoter of Rhodococcus rhodochrous that has minimal basal expression in the absence of induction, for use in mycobacteria...
- Targets for short-course TB therapy Christopher Sassetti; Fiscal Year: 2008..Short-course therapy could impact the worldwide tuberculosis epidemic both by making treatment more widely available and by reducing the rate at which drug-resistant strains emerge. [unreadable] [unreadable] [unreadable]..
- A New Transient Kinetic Solvent Isotope Effect ApproachHARVEY FISHER; Fiscal Year: 2006..The validity of our interpretations will in turn be tested by application of our transient-state solvent KIE approach to a number of relevant non-enzymatic reactions whose detailed mechanisms are well established. ..
- BIOSYNTHESIS AND METABOLISM OF CYCLOPENTANOIDSRonald Parry; Fiscal Year: 2001..The potential use of the CmaA gene for construction of hybrid peptide antibiotics containing L-alloisoleucine or coronamic acid will also be explored, using surfactin biosynthesis in B. subtilis as a model system. ..
- BIOSYNTHESIS OF SOME MICROBIAL METABOLITESRonald Parry; Fiscal Year: 2007..Future investigations of sparsomycin will focus on cloning the sparsomycin resistance gene from S. sparsogenes to understand the mechanism of self-resistance in this organism and to gain access to the biosynthetic genes. ..
- STRUCTURAL ORGANIZATION AND PROTEOMICS OF TBThomas Terwilliger; Fiscal Year: 2005..The structural and functional information obtained in this project is to be placed in the public domain by timely deposition in publicly available databases. ..
- GLYCOSIDASES AS RELATED TO SPHINGOLIPIDOSESYu Teh Li; Fiscal Year: 2008..Our ultimate goal is to produce recombinant enzymes and make these biomedically useful glycosidases available to investigators in various fields. ..