bacillus cereus

Summary

Summary: A species of rod-shaped bacteria that is a common soil saprophyte. Its spores are widespread and multiplication has been observed chiefly in foods. Contamination may lead to food poisoning.

Top Publications

  1. pmc ExsY and CotY are required for the correct assembly of the exosporium and spore coat of Bacillus cereus
    Matt J Johnson
    Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom
    J Bacteriol 188:7905-13. 2006
  2. pmc Bacillus cereus, a volatile human pathogen
    Edward J Bottone
    Division of Infectious Diseases, Box 1090, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Clin Microbiol Rev 23:382-98. 2010
  3. ncbi Anthrax
    M Mock
    Toxines et Pathogénie Bactérienne, CNRS URA 2172, Institut Pasteur, Paris Cedex 15, France
    Annu Rev Microbiol 55:647-71. 2001
  4. ncbi From soil to gut: Bacillus cereus and its food poisoning toxins
    Lotte P Stenfors Arnesen
    Department of Food Safety and Infection Biology, Norwegian School of Veterinary Science, Oslo, Norway
    FEMS Microbiol Rev 32:579-606. 2008
  5. pmc Expanding the known repertoire of virulence factors produced by Bacillus cereus through early secretome profiling in three redox conditions
    Gérémy Clair
    UMR408, Universite d Avignon et des Pays de Vaucluse, F 84000 Avignon, France
    Mol Cell Proteomics 9:1486-98. 2010
  6. pmc DNA as an adhesin: Bacillus cereus requires extracellular DNA to form biofilms
    Sebastien Vilain
    Department of Biology and Microbiology, South Dakota State University, Brookings, SD 57007, USA
    Appl Environ Microbiol 75:2861-8. 2009
  7. pmc Enterotoxigenic profiles of food-poisoning and food-borne Bacillus cereus strains
    Marie Helene Guinebretiere
    Institut National de la Recherche Agronomique, UMR A408 Sécurité et Qualité des Produits d Origine Végétale, INRA, Domaine Saint Paul, Site Agroparc, F 84914 Avignon Cedex 9, France
    J Clin Microbiol 40:3053-6. 2002
  8. ncbi What sets Bacillus anthracis apart from other Bacillus species?
    Anne Brit Kolstø
    Laboratory for Microbial Dynamics and Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo 0316, Norway
    Annu Rev Microbiol 63:451-76. 2009
  9. ncbi The effect of lemon, orange and bergamot essential oils and their components on the survival of Campylobacter jejuni, Escherichia coli O157, Listeria monocytogenes, Bacillus cereus and Staphylococcus aureus in vitro and in food systems
    K Fisher
    School of Health, The University of Northampton, Northampton, UK
    J Appl Microbiol 101:1232-40. 2006
  10. pmc The PlcR virulence regulon of Bacillus cereus
    Michel Gohar
    INRA, Génétique microbienne et Environnement, Guyancourt, France michel gohar jouy inra fr
    PLoS ONE 3:e2793. 2008

Detail Information

Publications326 found, 100 shown here

  1. pmc ExsY and CotY are required for the correct assembly of the exosporium and spore coat of Bacillus cereus
    Matt J Johnson
    Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom
    J Bacteriol 188:7905-13. 2006
    The exosporium-defective phenotype of a transposon insertion mutant of Bacillus cereus implicated ExsY, a homologue of B. subtilis cysteine-rich spore coat proteins CotY and CotZ, in assembly of an intact exosporium...
  2. pmc Bacillus cereus, a volatile human pathogen
    Edward J Bottone
    Division of Infectious Diseases, Box 1090, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Clin Microbiol Rev 23:382-98. 2010
    b>Bacillus cereus is a Gram-positive aerobic or facultatively anaerobic, motile, spore-forming, rod-shaped bacterium that is widely distributed environmentally. While B...
  3. ncbi Anthrax
    M Mock
    Toxines et Pathogénie Bactérienne, CNRS URA 2172, Institut Pasteur, Paris Cedex 15, France
    Annu Rev Microbiol 55:647-71. 2001
    ..Spore-structure analysis could contribute to the improvement of human nonliving vaccines. The phylogeny of B. anthracis within the Bacillus cereus group is also reviewed.
  4. ncbi From soil to gut: Bacillus cereus and its food poisoning toxins
    Lotte P Stenfors Arnesen
    Department of Food Safety and Infection Biology, Norwegian School of Veterinary Science, Oslo, Norway
    FEMS Microbiol Rev 32:579-606. 2008
    b>Bacillus cereus is widespread in nature and frequently isolated from soil and growing plants, but it is also well adapted for growth in the intestinal tract of insects and mammals...
  5. pmc Expanding the known repertoire of virulence factors produced by Bacillus cereus through early secretome profiling in three redox conditions
    Gérémy Clair
    UMR408, Universite d Avignon et des Pays de Vaucluse, F 84000 Avignon, France
    Mol Cell Proteomics 9:1486-98. 2010
    The pathogen Bacillus cereus causes diarrheal disease in humans. In the small intestine, B. cereus has to deal with anaerobiosis, low oxidoreduction potential, and carbohydrate limitation conditions...
  6. pmc DNA as an adhesin: Bacillus cereus requires extracellular DNA to form biofilms
    Sebastien Vilain
    Department of Biology and Microbiology, South Dakota State University, Brookings, SD 57007, USA
    Appl Environ Microbiol 75:2861-8. 2009
    The soil saprophyte Bacillus cereus forms biofilms at solid-liquid interfaces...
  7. pmc Enterotoxigenic profiles of food-poisoning and food-borne Bacillus cereus strains
    Marie Helene Guinebretiere
    Institut National de la Recherche Agronomique, UMR A408 Sécurité et Qualité des Produits d Origine Végétale, INRA, Domaine Saint Paul, Site Agroparc, F 84914 Avignon Cedex 9, France
    J Clin Microbiol 40:3053-6. 2002
    ..Unlike diarrheal strains, food-borne strains showed frequent nhe and hbl gene polymorphisms and were often low toxin producers...
  8. ncbi What sets Bacillus anthracis apart from other Bacillus species?
    Anne Brit Kolstø
    Laboratory for Microbial Dynamics and Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo 0316, Norway
    Annu Rev Microbiol 63:451-76. 2009
    ..cereus and B. thuringiensis. Coevolution of the B. anthracis chromosome with its plasmids may be the basis for the successful development and uniqueness of the B. anthracis lineage...
  9. ncbi The effect of lemon, orange and bergamot essential oils and their components on the survival of Campylobacter jejuni, Escherichia coli O157, Listeria monocytogenes, Bacillus cereus and Staphylococcus aureus in vitro and in food systems
    K Fisher
    School of Health, The University of Northampton, Northampton, UK
    J Appl Microbiol 101:1232-40. 2006
    ..To investigate the effectiveness of oils and vapours of lemon (Citrus limon), sweet orange (Citrus sinensis) and bergamot (Citrus bergamia) and their components against a number of common foodborne pathogens...
  10. pmc The PlcR virulence regulon of Bacillus cereus
    Michel Gohar
    INRA, Génétique microbienne et Environnement, Guyancourt, France michel gohar jouy inra fr
    PLoS ONE 3:e2793. 2008
    PlcR is a Bacillus cereus transcriptional regulator, which activates gene expression by binding to a nucleotidic sequence called the 'PlcR box'...
  11. ncbi Bacillus cereus bacteremia outbreak due to contaminated hospital linens
    T Sasahara
    Department of Infection and Immunity, School of Medicine, Jichi Medical University, 3311 1 Yakushiji, Shimotsuke, Tochigi, 329 0498, Japan
    Eur J Clin Microbiol Infect Dis 30:219-26. 2011
    We describe an outbreak of Bacillus cereus bacteremia that occurred at Jichi Medical University Hospital in 2006. This study aimed to identify the source of this outbreak and to implement appropriate control measures...
  12. pmc The phenolic hydroxyl group of carvacrol is essential for action against the food-borne pathogen Bacillus cereus
    A Ultee
    Wageningen Centre for Food Sciences, Department of Preservation Technology and Food Safety, Agrotechnological Research Institute ATO B V, Wageningen, The Netherlands
    Appl Environ Microbiol 68:1561-8. 2002
    ..The resulting collapse of the proton motive force and depletion of the ATP pool eventually lead to cell death...
  13. pmc Characterization of type II and III restriction-modification systems from Bacillus cereus strains ATCC 10987 and ATCC 14579
    Shuang yong Xu
    New England Biolabs, Inc, Ipswich, Massachusetts, USA
    J Bacteriol 194:49-60. 2012
    The genomes of two Bacillus cereus strains (ATCC 10987 and ATCC 14579) have been sequenced. Here, we report the specificities of type II/III restriction (R) and modification (M) enzymes...
  14. ncbi A cell-cell communication system regulates protease production during sporulation in bacteria of the Bacillus cereus group
    Stéphane Perchat
    INRA, UMR 1319 Micalis, La Minière, 78280 Guyancourt, France
    Mol Microbiol 82:619-33. 2011
    ..We investigated the role of one such regulator, NprR, in bacteria of the Bacillus cereus group. We show that NprR is a transcriptional regulator whose activity depends on the NprX signalling peptide...
  15. pmc Molecular basis for group-specific activation of the virulence regulator PlcR by PapR heptapeptides
    L Bouillaut
    INRA, UR1249, F 78285 Guyancourt, France
    Nucleic Acids Res 36:3791-801. 2008
    ..system that controls the expression of extra-cellular virulence factors in various species of the Bacillus cereus group. PlcR and PapR alleles are clustered into four groups defining four pherotypes...
  16. ncbi The hidden lifestyles of Bacillus cereus and relatives
    G B Jensen
    National Institute of Occupational Health, Lersø Parkallé 105, 2100 Copenhagen, Denmark
    Environ Microbiol 5:631-40. 2003
    b>Bacillus cereus sensu lato, the species group comprising Bacillus anthracis, Bacillus thuringiensis and B. cereus (sensu stricto), has previously been scrutinized regarding interspecies genetic correlation and pathogenic characteristics...
  17. ncbi Haemolysin II is a Bacillus cereus virulence factor that induces apoptosis of macrophages
    Seav Ly Tran
    INRA, Unité MICALIS, UMR 1319, Equipe GME, La Minière, 78285 Guyancourt, France
    Cell Microbiol 13:92-108. 2011
    b>Bacillus cereus is a Gram-positive spore-forming bacterium causing food poisoning and serious opportunistic infections. These infections are characterized by bacterial accumulation despite the recruitment of phagocytic cells...
  18. pmc Fatal family outbreak of Bacillus cereus-associated food poisoning
    Katelijne Dierick
    Institute of Public Health, Food Section, 14 Juliette Wijtsman Str, B 1050 Brussels, Belgium
    J Clin Microbiol 43:4277-9. 2005
    b>Bacillus cereus is a well-known cause of food-borne illness, but infection with this organism is not commonly reported because of its usually mild symptoms...
  19. pmc The InhA metalloproteases of Bacillus cereus contribute concomitantly to virulence
    Elisabeth Guillemet
    Unité Génétique Microbienne et Environnement, INRA, La Minière, 78285 Guyancourt Cedex, France
    J Bacteriol 192:286-94. 2010
    The virulence of Bacillus cereus requires that bacteria have the capacity to colonize their host, degrade specific tissues, and circumvent the host immune system...
  20. pmc Three Bacillus cereus bacteriophage endolysins are unrelated but reveal high homology to cell wall hydrolases from different bacilli
    M J Loessner
    Institut fur Mikrobiologie, Forschungszentrum fur Milch und Lebensmittel Weihenstephan, Technische Universitat Munchen, Freising, Germany
    J Bacteriol 179:2845-51. 1997
    The ply genes encoding the endolysin proteins from Bacillus cereus phages Bastille, TP21, and 12826 were identified, cloned, and sequenced...
  21. pmc Growth of microorganisms in total parenteral nutrition solutions containing lipid
    Takashi Kuwahara
    Preclinical Assessment Department, Otsuka Pharmaceutical Factory, Inc, Tokushima, Japan
    Int J Med Sci 7:101-9. 2010
    ..nutrition (TPN) solutions, we investigated the growth of the major causes of catheter-related blood stream infection (Staphylococcus aureus, Serratia marcescens, Bacillus cereus, and Candida albicans) in TPN solutions containing lipid.
  22. ncbi Extended and global phylogenetic view of the Bacillus cereus group population by combination of MLST, AFLP, and MLEE genotyping data
    Nicolas J Tourasse
    Laboratory for Microbial Dynamics LaMDa and Department of Pharmaceutical Biosciences Microbiology, University of Oslo, N 0316 Oslo, Norway
    Food Microbiol 28:236-44. 2011
    The Bacillus cereus group of bacteria includes species that can cause food-poisoning or spoilage, such as B. cereus, as well as Bacillus anthracis, the cause of anthrax...
  23. pmc Mechanisms of action of carvacrol on the food-borne pathogen Bacillus cereus
    A Ultee
    Agrotechnological Research Institute, 6700 AA Wageningen, The Netherlands
    Appl Environ Microbiol 65:4606-10. 1999
    ..thyme, was studied for its effect on bioenergetic parameters of vegetative cells of the food-borne pathogen Bacillus cereus. Incubation for 30 min in the presence of 1 to 3 mM carvacrol reduced the viable cell numbers exponentially...
  24. ncbi Ecological diversification in the Bacillus cereus Group
    Marie Helene Guinebretiere
    Institut National de Recherche Agronomique, UMR A408 Sécurité et Qualité des Produits d Origine Végétale, INRA, Domaine Saint Paul, Site Agroparc, F 84914 Avignon Cedex 9, France
    Environ Microbiol 10:851-65. 2008
    The Bacillus cereus Group comprises organisms that are widely distributed in the environment and are of health and economic interest. We demonstrate an 'ecotypic' structure of populations in the B...
  25. pmc Quantitative analysis of population heterogeneity of the adaptive salt stress response and growth capacity of Bacillus cereus ATCC 14579
    Heidy M W den Besten
    TI Food and Nutrition, Wageningen, The Netherlands
    Appl Environ Microbiol 73:4797-804. 2007
    ..The growth dynamics of Bacillus cereus ATCC 14579 during mild and severe salt stress exposure were investigated for the population as a whole in ..
  26. pmc Iron regulates expression of Bacillus cereus hemolysin II via global regulator Fur
    Elena Sineva
    Laboratory of Molecular Microbiology, Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, Russia
    J Bacteriol 194:3327-35. 2012
    ..b>Bacillus cereus is a widely distributed bacterium with distinct pathogenic properties...
  27. ncbi Expression of Bacillus cereus hemolysin II in Bacillus subtilis renders the bacteria pathogenic for the crustacean Daphnia magna
    Elena V Sineva
    Laboratory of Molecular Microbiology, Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, Russia
    FEMS Microbiol Lett 299:110-9. 2009
    Hemolysin II (HlyII) is a pore-forming toxin of the opportunistic pathogen Bacillus cereus. Despite our understanding of the mechanism of HlyII cytotoxicity in vitro, many of its characteristics, including potential target cells, ..
  28. ncbi A new Bacillus cereus DNA-binding protein, HlyIIR, negatively regulates expression of B. cereus haemolysin II
    Zhanna I Budarina
    The Institute of Biochemistry and Physiology of Micro organisms, Nauki Avenue, 5, Pushchino, 142292 Russia
    Microbiology 150:3691-701. 2004
    Haemolysin II, HlyII, is one of several cytotoxic proteins produced by Bacillus cereus, an opportunistic human pathogen that causes food poisoning. The hlyII gene confers haemolytic activity to Escherichia coli cells. Here a new B...
  29. ncbi Bacillus cereus nosocomial infection from reused towels in Japan
    S Dohmae
    Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
    J Hosp Infect 69:361-7. 2008
    It was noticed that there was an increase in Bacillus cereus nosocomial infections in the summer from 2000 to 2005. In 2005, five bloodstream infections occurred in five patients related to catheter use...
  30. pmc Role of the five RNA helicases in the adaptive response of Bacillus cereus ATCC 14579 cells to temperature, pH, and oxidative stresses
    Franck Pandiani
    INRA, UMR408 Sécurité et Qualité des Produits d Origine Végétale, Avignon, France
    Appl Environ Microbiol 77:5604-9. 2011
    In this study, growth rates and lag times of the five RNA helicase-deleted mutants of Bacillus cereus ATCC 14579 were compared to those of the wild-type strain under thermal, oxidative, and pH stresses...
  31. ncbi The InhA1 metalloprotease allows spores of the B. cereus group to escape macrophages
    Nalini Ramarao
    Unité Génétique Microbienne et Environnement, Institut National de la Recherche Agronomique, La Minière, 78285 Guyancourt Cedex, France
    Cell Microbiol 7:1357-64. 2005
    Bacteria of the Bacillus cereus group are resistant to the immune systems of various hosts and establish potent infections, implying that bacteria circumvent the bactericidal activity of host phagocytic cells...
  32. ncbi Bacillus cereus, the causative agent of an emetic type of food-borne illness
    Monika Ehling-Schulz
    Abt Mikrobiologie, ZIEL, Technische Universitat Munchen, Freising, Germany
    Mol Nutr Food Res 48:479-87. 2004
    b>Bacillus cereus is the causative agent of two distinct forms of gastroenteritic disease connected to food-poisoning. It produces one emesis-causing toxin and three enterotoxins that elicit diarrhea...
  33. ncbi Rapid degradation of N-3-oxo-acylhomoserine lactones by a Bacillus cereus isolate from Malaysian rainforest soil
    Kok Gan Chan
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
    Antonie Van Leeuwenhoek 98:299-305. 2010
    ..KM1S was clustered closely to Bacillus cereus by 16S ribosomal DNA sequence analysis...
  34. pmc Low concentrations of bile salts induce stress responses and reduce motility in Bacillus cereus ATCC 14579 [corrected]
    Simen M Kristoffersen
    Department of Molecular Biosciences, University of Oslo, PB1041 Blindern, 0316 Oslo, Norway
    J Bacteriol 189:5302-13. 2007
    Tolerance to bile salts was investigated in forty Bacillus cereus strains, including 17 environmental isolates, 11 dairy isolates, 3 isolates from food poisoning outbreaks, and 9 other clinical isolates...
  35. ncbi PCR fingerprinting of whole genomes: the spacers between the 16S and 23S rRNA genes and of intergenic tRNA gene regions reveal a different intraspecific genomic variability of Bacillus cereus and Bacillus licheniformis [corrected]
    D Daffonchio
    Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche DISTAM, Universita degli Studi, Milano, Italy
    Int J Syst Bacteriol 48:107-16. 1998
    Genomic diversity in 21 strains of Bacillus cereus and 10 strains of Bacillus licheniformis was investigated by random amplified polymorphic DNA (RAPD) analysis, which samples the whole genome, and by two PCR fingerprinting techniques ..
  36. pmc A Bacillus cereus cytolytic determinant, cereolysin AB, which comprises the phospholipase C and sphingomyelinase genes: nucleotide sequence and genetic linkage
    M S Gilmore
    Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City 73190
    J Bacteriol 171:744-53. 1989
    A cloned cytolytic determinant from the genome of Bacillus cereus GP-4 has been characterized at the molecular level. Nucleotide sequence determination revealed the presence of two open reading frames...
  37. pmc Biosurfactant production and surface translocation are regulated by PlcR in Bacillus cereus ATCC 14579 under low-nutrient conditions
    Yi Huang Hsueh
    Department of Bacteriology, Food Research Institute, University of Wisconsin Madison, 1550 Linden Drive, Madison, WI 53706, USA
    Appl Environ Microbiol 73:7225-31. 2007
    b>Bacillus cereus ATCC 14579 can respond to nutrient changes by adopting different forms of surface translocation. The B...
  38. pmc Bacillus cereus cytotoxins Hbl, Nhe and CytK are secreted via the Sec translocation pathway
    Annette Fagerlund
    Norwegian School of Veterinary Science, Department of Food Safety and Infection Biology, PO Box 8146 Dep, N 0033 Oslo, Norway
    BMC Microbiol 10:304. 2010
    b>Bacillus cereus and the closely related Bacillus thuringiensis are Gram positive opportunistic pathogens that may cause food poisoning, and the three secreted pore-forming cytotoxins Hbl, Nhe and CytK have been implicated as the ..
  39. ncbi Insertional mutagenesis reveals genes involved in Bacillus cereus ATCC 14579 growth at low temperature
    Veronique Broussolle
    INRA, UMR Securite et Qualite des Produits d Origine Vegetale, Avignon, France
    FEMS Microbiol Lett 306:177-83. 2010
    Transposon mutagenesis of Bacillus cereus ATCC 14579 yielded cold-sensitive mutants...
  40. pmc Crystal structure of the phosphatidylinositol-specific phospholipase C from Bacillus cereus in complex with myo-inositol
    D W Heinz
    Institut fur Organische Chemie und Biochemie, Universitat Freiburg, Germany
    EMBO J 14:3855-63. 1995
    ..The crystal structure of PI-PLC from Bacillus cereus (EC 3.1.4.10) has been solved at 2.6 A resolution and refined to a crystallographic R factor of 18.7%...
  41. ncbi Comparative analysis of the virulence of invertebrate and mammalian pathogenic bacteria in the oral insect infection model Galleria mellonella
    S Fedhila
    Unité Protéomie Fonctionnelle et Biopréservation Alimentaire, Institut Supérieur des Sciences, Biologiques Appliquées de Tunis, Universite Tunis El Manar, Tunis, Tunisia
    J Invertebr Pathol 103:24-9. 2010
    ..can function as an oral infection model for human and entomo-bacterial pathogens, we tested strains of Bacillus cereus, Bacillus anthracis, Enterococcus faecalis, Listeria monocytogenes, Pseudomonas aeruginosa and a Drosophila ..
  42. ncbi LmbE proteins from Bacillus cereus are de-N-acetylases with broad substrate specificity and are highly similar to proteins in Bacillus anthracis
    Alexandra Deli
    Department of Biology, Enzyme Biotechnology Group, University of Crete, Heraklion, Crete, Greece
    FEBS J 277:2740-53. 2010
    The genomes of Bacillus cereus and its closest relative Bacillus anthracis each contain two LmbE protein family homologs: BC1534 (BA1557) and BC3461 (BA3524)...
  43. pmc Trypan blue dye enters viable cells incubated with the pore-forming toxin HlyII of Bacillus cereus
    Seav Ly Tran
    INRA, Unité MICALIS, UMR 1319, Guyancourt, France
    PLoS ONE 6:e22876. 2011
    ..Here, we show that the pore-forming toxin HlyII of Bacillus cereus allows trypan blue staining of macrophage cells, despite the cells remaining viable and metabolically active...
  44. pmc Transcriptional responses of Bacillus cereus towards challenges with the polysaccharide chitosan
    Hilde Mellegård
    Department of Food Safety and Infection Biology, Norwegian School of Veterinary Science, Oslo, Norway
    PLoS ONE 6:e24304. 2011
    ..This paper reports the transcriptome profiling using DNA microarrays of the type-strain of Bacillus cereus (ATCC 14579) exposed to subinhibitory concentrations of two water-soluble chitosan preparations with defined ..
  45. ncbi Influence of carvacrol on growth and toxin production by Bacillus cereus
    A Ultee
    Agrotechnological Research Institute ATO DLO, Wageningen, The Netherlands Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    Int J Food Microbiol 64:373-8. 2001
    The natural antimicrobial compound carvacrol was investigated for its effect on diarrheal toxin production by Bacillus cereus. Carvacrol (0-0.06 mg/ml) reduced the viable count and the maximal specific growth rate (mumax) of B...
  46. ncbi Bacillus cereus food poisoning and its toxins
    Jean L Schoeni
    Department of Food Microbiology and Toxicology, Food Research Institute, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Food Prot 68:636-48. 2005
    ..b>Bacillus cereus causes two types of food poisoning, the emetic and diarrheal syndromes, and a variety of local and systemic ..
  47. pmc Global transcriptome analysis of Bacillus cereus ATCC 14579 in response to silver nitrate stress
    Malli Mohan Ganesh Babu
    Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Tamil Nadu, India
    J Nanobiotechnology 9:49. 2011
    Silver nanoparticles (AgNPs) were synthesized using Bacillus cereus strains. Earlier, we had synthesized monodispersive crystalline silver nanoparticles using B. cereus PGN1 and ATCC14579 strains...
  48. pmc The dlt operon of Bacillus cereus is required for resistance to cationic antimicrobial peptides and for virulence in insects
    Z Abi Khattar
    INRA, UMR 1133, Laboratoire EMIP, Place Eugene Bataillon, F 34095 Montpellier, France
    J Bacteriol 191:7063-73. 2009
    ..We investigated the role of the dlt operon in insect virulence by inactivating this operon in Bacillus cereus, which is both an opportunistic human pathogen and an insect pathogen...
  49. pmc Differential involvement of the five RNA helicases in adaptation of Bacillus cereus ATCC 14579 to low growth temperatures
    Franck Pandiani
    INRA, UMR408, Sécurité et Qualité des Produits d Origine Végétale, Avignon, France
    Appl Environ Microbiol 76:6692-7. 2010
    b>Bacillus cereus ATCC 14579 possesses five RNA helicase-encoding genes overexpressed under cold growth conditions. Out of the five corresponding mutants, only the ΔcshA, ΔcshB, and ΔcshC strains were cold sensitive...
  50. ncbi Virulence of Bacillus cereus: a multivariate analysis
    J Minnaard
    Centro de Investigación y Desarrollo en Criotecnología de Alimentos, Catedra de Microbiologia, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina
    Int J Food Microbiol 116:197-206. 2007
    Biological activity and presence of DNA sequences related to virulence genes were studied in 21 strains of the Bacillus cereus group...
  51. pmc Whole-genome phylogenies of the family Bacillaceae and expansion of the sigma factor gene family in the Bacillus cereus species-group
    Timothy R Schmidt
    Department of Microbiology and Immunology, Oklahoma University Health Sciences Center, Oklahoma City, OK 73117 USA
    BMC Genomics 12:430. 2011
    The Bacillus cereus sensu lato group consists of six species (B. anthracis, B. cereus, B. mycoides, B. pseudomycoides, B. thuringiensis, and B. weihenstephanensis)...
  52. ncbi Two HlyIIR dimers bind to a long perfect inverted repeat in the operator of the hemolysin II gene from Bacillus cereus
    Ekaterina A Rodikova
    Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Prospekt Nauki 5, Pushchino, Moscow Region 142290, Russia
    FEBS Lett 581:1190-6. 2007
    ..Two HlyIIR dimers were found to bind to native operator independently with Kd level in the nanomolar range. The minimal HlyIIR binding site was identified as a half of the long DNA perfect inverted repeat...
  53. ncbi Detection of large plasmids from the Bacillus cereus group
    Lars Andrup
    National Research Centre for the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen, Denmark
    Plasmid 59:139-43. 2008
    The members of the Bacillus cereus group, Bacillus anthracis, Bacillus thuringiensis, and B. cereus senso stricto, are largely defined by their content of large plasmids, which encode major virulence factors...
  54. ncbi Hemolysis induced by Bacillus cereus sphingomyelinase
    Masataka Oda
    Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro cho, Tokushima, Japan 770 8514
    Biochim Biophys Acta 1798:1073-80. 2010
    b>Bacillus cereus sphingomyelinase (Bc-SMase) induces hemolysis of sheep erythrocytes which contain large amounts of sphingomyelin...
  55. ncbi Comparison of cytotoxin cytK promoters from Bacillus cereus strain ATCC 14579 and from a B. cereus food-poisoning strain
    Julien Brillard
    Institut Pasteur, Génétique et Physiologie des Bacillus Pathogènes, Département de Microbiologie Fondamentale et Médicale, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    Microbiology 150:2699-705. 2004
    The cytotoxin CytK produced by Bacillus cereus is believed to be involved in food-borne diseases...
  56. ncbi Regulation of toxin production by Bacillus cereus and its food safety implications
    Siele Ceuppens
    Ghent University, Faculty of Bioscience Engineering, Laboratory of Food Microbiology and Food Preservation, Ghent, Belgium
    Crit Rev Microbiol 37:188-213. 2011
    ..The food safety aspects and management tools such as temperature control, food preservatives and modified atmosphere packaging are discussed specifically for B. cereus emetic and diarrheal toxin production...
  57. pmc Monoclonal antibodies neutralize Bacillus cereus Nhe enterotoxin by inhibiting ordered binding of its three exoprotein components
    Andrea Didier
    Department of Veterinary Sciences, Faculty of Veterinary Medicine, Ludwig Maximilians Universitat Munchen, Oberschleissheim, Germany
    Infect Immun 80:832-8. 2012
    The Nhe enterotoxin from Bacillus cereus is known to induce cytotoxicity on Vero and CaCo-2 cells by ordered binding of its single components NheA, NheB, and NheC...
  58. pmc IlsA, a unique surface protein of Bacillus cereus required for iron acquisition from heme, hemoglobin and ferritin
    Nadine Daou
    INRA UR1249 Génétique Microbienne et Environnement, La Minière, Guyancourt, France
    PLoS Pathog 5:e1000675. 2009
    The human opportunistic pathogen Bacillus cereus belongs to the B. cereus group that includes bacteria with a broad host spectrum. The ability of these bacteria to colonize diverse hosts is reliant on the presence of adaptation factors...
  59. pmc Contamination of hospital linen by Bacillus cereus
    D Barrie
    Department of Medical Microbiology, Charing Cross and Westminster Medical School, London
    Epidemiol Infect 113:297-306. 1994
    An investigation into two cases of post-operative Bacillus cereus meningitis revealed that hospital linen laundered by a batch continuous washing machine was heavily contaminated by B. cereus spores...
  60. pmc Sudden death of a young adult associated with Bacillus cereus food poisoning
    Maria Naranjo
    Scientific Institute of Public Health, 14 Juliette Wytsman Str, B 1050 Brussels, Belgium
    J Clin Microbiol 49:4379-81. 2011
    ..A 20-year-old man died following the ingestion of pasta contaminated with Bacillus cereus. Emetic strains of B. cereus were isolated, and high levels of cereulide (14...
  61. ncbi Complete nucleotide sequence and molecular characterization of hemolysin II gene from Bacillus cereus
    G Baida
    Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Moscow Region, 142292, Pushchino, Russia
    FEMS Microbiol Lett 180:7-14. 1999
    Hemolysin II gene from Bacillus cereus VKM-B771 has been sequenced. The deduced primary translation product consists of 412 amino acid residues which corresponds to the protein with an M(r) of 45.6 kDa...
  62. pmc Characterization and genomic analysis of chromate resistant and reducing Bacillus cereus strain SJ1
    Minyan He
    State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China
    BMC Microbiol 10:221. 2010
    ..Our main aim was to investigate chromate resistance and reduction by Bacillus cereus SJ1, and to further study the underlying mechanisms at the molecular level using the obtained genome sequence.
  63. pmc Characterization of Bacillus probiotics available for human use
    Le H Duc
    School of Biological Sciences, Royal Holloway, University of London, Egham, Surrey TW20 OEX, United Kingdom
    Appl Environ Microbiol 70:2161-71. 2004
    Bacillus species (Bacillus cereus, Bacillus clausii, Bacillus pumilus) carried in five commercial probiotic products consisting of bacterial spores were characterized for potential attributes (colonization, immunostimulation, and ..
  64. ncbi The occurrence of Bacillus cereus, B. thuringiensis and B. mycoides in Chinese pasteurized full fat milk
    Guoping Zhou
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
    Int J Food Microbiol 121:195-200. 2008
    ..The single B. mycoides isolate harbored nheA and nheC genes. The data provides information for further evaluating the effect of B. cereus-like bacteria on food safety of Chinese milk products...
  65. ncbi Bacterial contamination in the environment of food factories processing ready-to-eat fresh vegetables
    K Kaneko
    Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Japan
    J Food Prot 62:800-4. 1999
    ..b>Bacillus cereus was isolated from 9 of 86 and 17 of 85 samples examined before and after operation with the number of 2...
  66. ncbi Prevalence of Bacillus cereus bacteriophages in fermented foods and characterization of phage JBP901
    Hakdong Shin
    Department of Food and Animal Biotechnology, Center for Agricultural Biomaterials and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea
    Res Microbiol 162:791-7. 2011
    b>Bacillus cereus is widely distributed in the environment and is responsible for foodborne illnesses, causing diarrhea and vomiting. In this study, the prevalence of B...
  67. pmc Identification of sigmaB-dependent genes in Bacillus cereus by proteome and in vitro transcription analysis
    Willem van Schaik
    Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    J Bacteriol 186:4100-9. 2004
    The alternative sigma factor sigmaB of the food pathogen Bacillus cereus is activated upon stress exposure and plays a role in the adaptive response of vegetative cells...
  68. pmc InhA1, NprA, and HlyII as candidates for markers to differentiate pathogenic from nonpathogenic Bacillus cereus strains
    Céline Cadot
    INRA, Unité MICALIS, GME, La Minière, Guyancourt, France
    J Clin Microbiol 48:1358-65. 2010
    b>Bacillus cereus is found in food, soil, and plants, and the ability to cause food-borne diseases and opportunistic infection presumably varies among strains...
  69. pmc Identification of Bacillus cereus genes specifically expressed during growth at low temperatures
    Julien Brillard
    INRA, UMR408, Site Agroparc, 84914 Avignon Cedex 9, France
    Appl Environ Microbiol 76:2562-73. 2010
    The mechanisms involved in the ability of Bacillus cereus to multiply at low temperatures were investigated. It was assumed that many genes involved in cold acclimation would be upregulated at low temperatures...
  70. pmc Differentiation of Bacillus anthracis, B. cereus, and B. thuringiensis by using pulsed-field gel electrophoresis
    Wenwan Zhong
    Bioscience Division, MS M888, Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    Appl Environ Microbiol 73:3446-9. 2007
    ..cereus and B. thuringiensis isolates by cluster analysis of the whole-genome macrorestriction enzyme digestion patterns generated by NotI...
  71. ncbi Analysis of acid-stressed Bacillus cereus reveals a major oxidative response and inactivation-associated radical formation
    Maarten Mols
    Top Institute Food and Nutrition, Wageningen, The Netherlands
    Environ Microbiol 12:873-85. 2010
    Acid stress resistance of the food-borne human pathogen Bacillus cereus may contribute to its survival in acidic environments, such as encountered in soil, food and the human gastrointestinal tract. The acid stress responses of B...
  72. pmc The ExsA protein of Bacillus cereus is required for assembly of coat and exosporium onto the spore surface
    Karen Bailey-Smith
    Krebs Institute, Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom
    J Bacteriol 187:3800-6. 2005
    The outermost layer of spores of the Bacillus cereus family is a loose structure known as the exosporium. Spores of a library of Tn917-LTV1 transposon insertion mutants of B...
  73. ncbi Mechanism of action of hemolysin III from Bacillus cereus
    G E Baida
    Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, Russia
    Biochim Biophys Acta 1284:122-4. 1996
    b>Bacillus cereus hemolysin III activity was tested in crude extracts, from Escherichia coli carrying the hly-III gene. It was concluded that hemolysin III is a pore-forming hemolysin with functional pore diameter of about 3-3.5 nm...
  74. ncbi Structure of the exosporium and sublayers of spores of the Bacillus cereus family revealed by electron crystallography
    David A Ball
    Krebs Institute for Biomolecular Research, Department of Molecular Biology and Biotechnology, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, UK
    Mol Microbiol 68:947-58. 2008
    ..electron microscopy and image analysis, we have characterized crystalline fragments from the exosporium of Bacillus cereus, B. thuringiensis and B. anthracis strains and identified up to three distinct crystal types...
  75. ncbi Prevalence and diversity of insertion sequences in the genome of Bacillus thuringiensis YBT-1520 and comparison with other Bacillus cereus group members
    Ning Qiu
    State Key Laboratory of Agricultural Microbiology and National Engineering Research Center of Microbial Pesticides, Huazhong Agricultural University, Wuhan, Hubei, China
    FEMS Microbiol Lett 310:9-16. 2010
    Members of the Bacillus cereus group are closely related bacteria that exhibit highly divergent pathogenic properties. Sequencing of Bacillus thuringiensis ssp...
  76. pmc Response of Bacillus cereus ATCC 14579 to challenges with sublethal concentrations of enterocin AS-48
    María J Grande Burgos
    Departamento de Ciencias de Salud Area de Microbiología, Facultad de Ciencias Experimentales, Universidad de Jaen, 23071 Jaen, Spain
    BMC Microbiol 9:227. 2009
    ..Here, we studied the effect of enterocin AS-48 challenges on vegetative cells of Bacillus cereus ATCC 14579 by use of transcriptome analysis.
  77. ncbi Comparative analysis of transcriptional and physiological responses of Bacillus cereus to organic and inorganic acid shocks
    Maarten Mols
    Top Institute Food and Nutrition, Wageningen, The Netherlands Laboratory of Food Microbiology, Wageningen University and Research Centre, The Netherlands
    Int J Food Microbiol 137:13-21. 2010
    Comparative phenotype and transcriptome analyses were performed with Bacillus cereus ATCC 14579 exposed to pH 5.5 set with different acidulants including hydrochloric acid (HCl), lactic acid (HL) and acetic acid (HAc)...
  78. ncbi The impact of oxygen availability on stress survival and radical formation of Bacillus cereus
    Maarten Mols
    Top Institute Food and Nutrition, Wageningen, The Netherlands Laboratory of Food Microbiology, Wageningen University, Wageningen, The Netherlands
    Int J Food Microbiol 135:303-11. 2009
    Both the growth and stress survival of two model Bacillus cereus strains, ATCC 14579 and ATCC 10987, were tested in three different conditions varying in oxygen availability, i.e., aerobic, microaerobic and anaerobic conditions. Both B...
  79. ncbi Assembly of pili on the surface of Bacillus cereus vegetative cells
    Jonathan M Budzik
    Department of Microbiology, University of Chicago, Chicago, IL 60637, USA
    Mol Microbiol 66:495-510. 2007
    Vegetative forms of Bacillus cereus are reported to form pili, thin protein filaments that protrude up to 1 mum from the bacterial surface...
  80. pmc A strain-variable bacteriocin in Bacillus anthracis and Bacillus cereus with repeated Cys-Xaa-Xaa motifs
    Daniel H Haft
    The J Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850, USA
    Biol Direct 4:15. 2009
    ..cereus, but has gone unrecognized because it is always encoded far from its maturation protein operon. Patterns of insertions and deletions among twenty-four variants suggest a repeating functional unit of Cys-Xaa-Xaa...
  81. pmc Bacillus cereus-induced permeability of the blood-ocular barrier during experimental endophthalmitis
    Andrea L Moyer
    Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Invest Ophthalmol Vis Sci 50:3783-93. 2009
    The purpose of this study was to determine to what extent blood-retinal barrier (BRB) permeability occurred during experimental Bacillus cereus endophthalmitis and whether tight junction alterations were involved in permeability.
  82. pmc The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold
    A Carfi
    Institut de Biologie Structurale Jean Pierre Ebel CEA CNRS, Laboratoire de Cristallographie Macromoléculaire, Grenoble, France
    EMBO J 14:4914-21. 1995
    The 3-D structure of Bacillus cereus (569/H/9) beta-lactamase (EC 3.5.2.6), which catalyses the hydrolysis of nearly all beta-lactams, has been solved at 2...
  83. pmc Comparative transcriptomic and phenotypic analysis of the responses of Bacillus cereus to various disinfectant treatments
    Mara Ceragioli
    Laboratory of Food Microbiology, Wageningen University, Wageningen, Netherlands
    Appl Environ Microbiol 76:3352-60. 2010
    ..In this study, the physiological and genome-wide transcriptional responses of Bacillus cereus ATCC 14579 exposed to four different disinfectants (benzalkonium chloride, sodium hypochlorite, hydrogen ..
  84. pmc Phenotypic and transcriptomic analyses of mildly and severely salt-stressed Bacillus cereus ATCC 14579 cells
    Heidy M W den Besten
    TI Food and Nutrition, Wageningen, The Netherlands
    Appl Environ Microbiol 75:4111-9. 2009
    ..In this study, exponentially growing cells of the pathogen Bacillus cereus ATCC 14579 were exposed to both mild (2...
  85. pmc The YvfTU two-component system is involved in plcR expression in Bacillus cereus
    Julien Brillard
    UMR408, Sécurité et Qualité des Produits d Origine Végétale, INRA, Universite d Avignon, F 84000 Avignon, France
    BMC Microbiol 8:183. 2008
    Most extracellular virulence factors produced by Bacillus cereus are regulated by the pleiotropic transcriptional activator PlcR. Among strains belonging to the B...
  86. ncbi Synergistic bactericidal effect of carvacrol, cinnamaldehyde or thymol and refrigeration to inhibit Bacillus cereus in carrot broth
    M Valero
    Departamento de Producción Vegetal y Microbiología, Escuela Politecnica Superior de Orihuela, Universidad Miguel Hernandez, Campus de Orihuela, Carretera de Beniel, Km 3 2, 03312 Orihuela, Alicante, Spain
    Food Microbiol 23:68-73. 2006
    ..was studied by examining their influence in the kinetics of growth from activated spores of four Bacillus cereus strains in tyndallized carrot broth over the temperature range 5-16 degrees C...
  87. ncbi Bacillus cereus meningoencephalitis in preterm infants: neuroimaging characteristics
    Maarten H Lequin
    Department of Radiology, Sophia Children s Hospital, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    AJNR Am J Neuroradiol 26:2137-43. 2005
    ..In this report we focus on the deleterious clinical course and imaging characteristics of proven Bacillus cereus meningoencephalitis.
  88. ncbi Purification and characterization of a solvent and detergent-stable novel protease from Bacillus cereus
    Kiran Kumar Doddapaneni
    Centre for Biotechnology, Institute of Science and Technology, Jawaharlal Nehru Technological University, Hyderabad, Andhra Pradesh, India
    Microbiol Res 164:383-90. 2009
    ..It was related to Bacillus cereus on the basis of 16S rRNA gene sequencing and biochemical properties...
  89. ncbi Degradation of raw feather by a novel high molecular weight extracellular protease from newly isolated Bacillus cereus DCUW
    Abhrajyoti Ghosh
    Department of Biochemistry, University of Calcutta, 700019, West Bengal, India
    J Ind Microbiol Biotechnol 35:825-34. 2008
    ..In the present study, we have demonstrated the degradation of feather waste by Bacillus cereus DCUW strain isolated during a functional screening based microbial diversity study on East Calcutta Wetland ..
  90. ncbi Exploring the evolution of the Bacillus cereus group repeat element bcr1 by comparative genome analysis of closely related strains
    Are Klevan
    Department of Pharmaceutical Biosciences Microbiology, University of Oslo, PO Box 1068 Blindern, 0316 Oslo, Norway
    Microbiology 153:3894-908. 2007
    bcr1 is a chromosomal approximately 155 bp repeated element found uniquely and ubiquitously in the Bacillus cereus group of Gram-positive bacteria; it exhibits several features characteristic of mobile elements, including a variable ..
  91. ncbi Incidence and characterization of diarrheal enterotoxins of fecal Bacillus cereus isolates associated with diarrhea
    Mariam Saleh Al-Khatib
    Department of Biological Sciences, Faculty of Science, University of Jordan, Amman 11942, Jordan
    Diagn Microbiol Infect Dis 59:383-7. 2007
    ..collected from patients with diarrhea and healthy controls without diarrhea to investigate the incidence of Bacillus cereus and its enterotoxins. B...
  92. ncbi Characterization of aerobic and anaerobic vegetative growth of the food-borne pathogen Bacillus cereus F4430/73 strain
    Eric Rosenfeld
    Laboraatoire de Biotechnologies et Chimie Bio organique FRE 2766 CNRS, Batiment Marie Curie, Pôle Sciences et Technologies, Universite de La Rochelle, 17042 La Rochelle Cedex 1, France
    Can J Microbiol 51:149-58. 2005
    The Gram-positive bacterium Bacillus cereus is a facultative anaerobe that is still poorly characterized metabolically. In this study, the aerobic vegetative growth and anaerobic vegetative growth of the food-borne pathogen B...
  93. pmc Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis
    Cliff S Han
    Department of Energy Joint Genome Institute, Bioscience Division, MS M888, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA
    J Bacteriol 188:3382-90. 2006
    Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis are closely related gram-positive, spore-forming bacteria of the B. cereus sensu lato group. While independently derived strains of B...
  94. ncbi Structure analysis of peptide deformylase from Bacillus cereus
    Jin Ho Moon
    Biomedical Research Center, Life Sciences Division, Korea Institute of Science and Technology, Seoul, Korea
    Proteins 61:217-20. 2005
  95. ncbi Cloning and primary structure of a new hemolysin gene from Bacillus cereus
    G E Baida
    Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, Russia
    Biochim Biophys Acta 1264:151-4. 1995
    A new hemolysin gene from Bacillus cereus VKM-B164 was cloned in Escherichia coli and sequenced. Deduced protein consists of 219 amino acids and has a molecular mass of 24.4 kDa...
  96. pmc An extracytoplasmic function sigma factor controls beta-lactamase gene expression in Bacillus anthracis and other Bacillus cereus group species
    Cana L Ross
    Department of Microbiology and Molecular Genetics, University of Texas Houston Medical School, Houston, Texas 77030, USA
    J Bacteriol 191:6683-93. 2009
    ..anthracis strains to beta-lactam antibiotics is intriguing considering that the closely related species Bacillus cereus and Bacillus thuringiensis typically produce beta-lactamases and the B...
  97. ncbi Brain abscesses resulting from Bacillus cereus and an Aspergillus-like mold
    Elene Psiachou-Leonard
    Department of Pediatric Oncology, Hippokration Hospital, Thessaloniki, Greece
    J Pediatr Hematol Oncol 24:569-71. 2002
    ....
  98. pmc Generation of thiocillin variants by prepeptide gene replacement and in vivo processing by Bacillus cereus
    Michael G Acker
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Chem Soc 131:17563-5. 2009
    ....
  99. pmc Proteomic analysis reveals differential protein expression by Bacillus cereus during biofilm formation
    Marinda C Oosthuizen
    School of Molecular and Cell Biology, University of the Witwatersrand, Wits, 2050, South Africa
    Appl Environ Microbiol 68:2770-80. 2002
    b>Bacillus cereus, a dairy-associated toxigenic bacterium, readily forms biofilms on various surfaces and was used to gain a better understanding of biofilm development by gram-positive aerobic rods. B...
  100. ncbi Identification and characterization of toxigenic Bacillus cereus isolates responsible for two food-poisoning outbreaks
    Emilia Ghelardi
    Dipartimento di Patologia Sperimentale, Biotecnologie Mediche, Infettivologia ed Epidemiologia, University of Pisa, Via San Zeno 35 39, 56127, Pisa, Italy
    FEMS Microbiol Lett 208:129-34. 2002
    The epidemiology of Bacillus cereus strains responsible for food poisoning is scantly known, mostly because the genotypic and toxigenic properties of the B...
  101. pmc CwpFM (EntFM) is a Bacillus cereus potential cell wall peptidase implicated in adhesion, biofilm formation, and virulence
    Seav Ly Tran
    INRA, Unité MICALIS UMR 1319, Equipe GME, La Minière, 78285 Guyancourt, France
    J Bacteriol 192:2638-42. 2010
    b>Bacillus cereus EntFM displays an NlpC/P60 domain, characteristic of cell wall peptidases. The protein is involved in bacterial shape, motility, adhesion to epithelial cells, biofilm formation, vacuolization of macrophages, and virulence...

Research Grants40

  1. Activation of PI Specific Phospholipase C Enzymes
    MARY FEDARKO ROBERTS; Fiscal Year: 2013
    ..Likewise some Bacillus cereus strains are opportunistic pathogens and PI-PLC cleavage of GPI-anchored proteins is likely to contribute to ..
  2. Chemistry, Structure and Biology of Thiol Transferases
    Richard N Armstrong; Fiscal Year: 2013
    ..and have obtained the genes, expressed and purified the FosB enzymes from several sources including Bacillus cereus, Bacillus anthracis and Staphylococcus aureus which puts us in an excellent position to accomplish this aim...
  3. Interaction between B. cereus RecQ helicase and topoisomerase III
    Zhiyu Li; Fiscal Year: 2010
    ..which possess one or two type IA topoisomerases and single RecQ helicase, some Gram-positive bacteria such as Bacillus cereus and Bacillus anthracis, the etiologic agent of anthrax, encode multiple chromosomal copies of type IA ..
  4. Structural basis of tetracycline resistance by efflux pump TetL
    DANENG WANG; Fiscal Year: 2013
    ..resistance efflux proteins (Tet) in Gram-positive bacterial pathogens, including Bacillus anthracis, Bacillus cereus, Streptococcus pneumoniae, and Staphylococcus aureus. Clostridium spp., Enterococcus spp. and Listeria spp...
  5. Exposporium determinants of Bacillus anthracis
    George C Stewart; Fiscal Year: 2013
    ..In addition, a number of endospore-forming human pathogens possess exosporia, including Bacillus cereus, Clostridium perfringens, and Clostridium difficile and a more detailed understanding of the exosporium of B...
  6. SURFACE PROTEIN ANCHORING IN GRAM-POSITIVE BACTERIA
    Olaf Schneewind; Fiscal Year: 2013
    ..b>Bacillus cereus pili are formed from two subunits, the tip protein (BcpB) and the major pilin (BcpA), which generates the ..
  7. Targeting Replication-Segregation of plasmid pX01 in Bacillus anthracis
    Debabrata RayChaudhuri; Fiscal Year: 2010
    ..The presence of mobile elements in pXO1 allows gene transfer to related Bacillus cereus family members...
  8. Surface Proteins of Bacillus anthracis
    Olaf Schneewind; Fiscal Year: 2013
    ..In B. anthracis, linear PDGA strands are linked to peptidoglycan and threaded across the S-layer. Bacillus cereus G9241, which causes anthrax-like respiratory disease, elaborates a hyaluronic acid capsule;its genetic ..
  9. Molecular Mechanism of Cation Channel Selectivity
    Youxing Jiang; Fiscal Year: 2013
    ..One is the non-selective, Ca2+ permeable cyclic nucleotide-gated (CNG) channels, using NaK from Bacillus cereus and its CNG- mimicking chimeras as model systems;the other is K+ selective channels, using a K+ selective NaK ..
  10. Experiment based genome mining of ribosomal natural products
    Bradley S Moore; Fiscal Year: 2013
    ..characterization of ribosomally encoded toxins secreted by pathogenic bacteria such as Staphylococcus aureus, Bacillus cereus and Clostridium difficile as well as defensins produced by higher eukaryotes such as marine snails, primates ..
  11. Structure and Function of a Phosphorylation Coupled Saccharide Transporter
    Ming Zhou; Fiscal Year: 2013
    ..To this end, we have solved the structure of a ChbC ortholog from Bacillus cereus (bcChbC), which has led us to propose hypotheses for how the transporter selectively binds sugar, ..
  12. Biosynthetic studies on the heterocycle-containing thiopeptide natural products
    LAURA CAROLINE BROWN; Fiscal Year: 2010
    ..are: (1) To elucidate the order of post-translational modifications during thiocillin biosynthesis in Bacillus cereus. Elucidation of the mechanism of thiocillin biosynthesis will require systematic double crossover knockouts ..
  13. Plasmid pXO2 Replication in Bacillus anthracis
    Saleem Khan; Fiscal Year: 2005
    ..Gene transfer can frequently occur between B. anthracis and closely related species such as Bacillus cereus, Bacillus thuringiensis and Bacillus mycoides, making it likely that the pXO1 and pXO2 plasmids could ..
  14. Escape of Bacillus anthracis from the phagsome
    Howard Goldfine; Fiscal Year: 2004
    ..Since the Ba PI-PLC ortholog is 94% identical in amino acid sequence to the PI-PLC from Bacillus cereus, it almost certainly has that enzymatic activity, but there are potential structural differences between the ..
  15. STRUCTURE/FUNCTION OF PI-SPECIFIC PHOSPHOLIPASE C
    O Griffith; Fiscal Year: 2001
    ..e. only unphosphorylated PI is cleaved. They are secreted by the Gram plus bacteria Bacillus cereus and the nearly identical B...
  16. METALLOENZYMES AND ANTIBIOTIC RESISTANCE IN BACTERIA
    Robert Shaw; Fiscal Year: 1992
    ..This proposal describes a study of the metallo-beta-lactamases produced by the bacterium Bacillus cereus. The experimental approach is multidisciplinary in nature in that it involves the use of a combination of ..
  17. Phospholipid-induced Motility in Bacillus cereus Group
    R Fall; Fiscal Year: 2004
    The goal of the proposed research is to characterize newly-discovered gliding motility in bacteria of the Bacillus cereus group. The B. cereus group, which includes pathogens of humans (B. cereus and B.anthracis) and insects (B...
  18. INTERFACIAL ACTIVATION OF WATER SOLUBLE PHOSPHOLIPASES
    Mary Roberts; Fiscal Year: 2003
    ..to understand on a molecular level the complex interfacial behavior of two water-soluble lipolytic enzymes: Bacillus cereus non-specific phospholipase C (PLC) and Streptomyces chromofuscus phospholipase D (PLD)...
  19. Novel Devices for Processing Bioterrorism Agents
    BITA NAKHAI; Fiscal Year: 2004
    ..A model system using Bacillus subtilis and Bacillus cereus will be employed to mimic the spores and vegetative cells of B. anthracis...
  20. SYNTHESIS OF NITROGEN CONTAINING NATURAL PRODUCTS
    Stephen Martin; Fiscal Year: 2010
    ..Secondly, the synthetic targets we have identified have significant potential as leads for the development of novel anticancer agents. ..
  21. Strategies for the Syntheses of Bioactive Targets
    Stephen Martin; Fiscal Year: 2010
    ..Secondly, the targets we have identified have significant potential as leads for the development of novel anticancer agents having improved biological profiles. ..
  22. Studies of Molecular Recognition in Biological Systems
    Stephen Martin; Fiscal Year: 2010
    ..Such tools are indispensable to medicinal chemists as they optimize ligand binding affinities and transform novel leads into selective and potent therapeutic agents to treat diseases. ..
  23. Anti-Trypanosomal Agents from a Neotropical Cloudforest
    WILLIAM SETZER; Fiscal Year: 2004
    ..The long-term benefit of this research project is the development of new medicines to treat patients with Chagas disease. ..
  24. STRATEGIES FOR INACTIVATING BACILLUS ANTHRACIS SPORES
    Arthur Aronson; Fiscal Year: 2003
    ..Once such reagents or methods have been identified, they will be tested on spores in various soils that should mimic natural environments and thus the conditions needed for the effective control of this bioweapon. ..
  25. Cloning and Engineering of Nicking enzymes
    Shuang yong Xu; Fiscal Year: 2004
    ..abstract_text> ..
  26. A universal DNA endonuclease
    Shuang yong Xu; Fiscal Year: 2005
    ..For isothermal applications of the universal nuclease at 50oC-70oC, the nuclease domain will be derived from thermophilic endonucleases. ..
  27. Engineering DNA nicking endonucleases
    Shuang yong Xu; Fiscal Year: 2006
    ..Under Phase II funding, this isothermal amplification method (NEMDA) will be optimized and the sensitivity will be improved. Finally, we will investigate the potential of NEMDA for detections of pathogens and its use in bio-prospecting. ..
  28. A Genetic System Able to Screen for Active DNA Demethylation
    Shuang yong Xu; Fiscal Year: 2006
    ..In addition, knowledge of the mechanism of demethylation could be crucial in converting fully differentiated adult stem cells into totipotent stem cells. [unreadable] [unreadable] [unreadable]..
  29. Measuring Metabolites using Riboswitch reports
    Ronald Breaker; Fiscal Year: 2006
    ..Moreover, bioinformatics searches can be expanded to uncover examples of known or new riboswitches in humans and other eukaryotes. ..
  30. Identifying targets for diagnosing oral candidiasis
    David Schofield; Fiscal Year: 2005
    ..Since Candida species are the most important fungal pathogen of the oral cavity, the rapid and accurate diagnosis of oral candidiasis using novel disease biomarkers will significantly improve oral health. ..
  31. ENGINEERING ALLOSTERIC RIBOZYMES AND DEOXYRIBOZYMES
    Ronald Breaker; Fiscal Year: 2002
    ..In addition, we will test the function of these 'molecular switches' in vivo, to establish a new method of controlled gene expression. ..
  32. Peptide Derivatives to treat Urinary Tract Infections
    Laszlo Otvos; Fiscal Year: 2003
    ..Our hope is that by the end of the grant period, we will be able to provide a pyrrhocoricin-derived peptide for ensuing US Food and Drug Administration-approved preclinical and clinical evaluation against urinary tract infections. ..
  33. The role of C1q in regulation of monocyte to dendritic cell transition
    Berhane Ghebrehiwet; Fiscal Year: 2010
    ..G w1' 0.N ..r v0, .a. ' in the long term, may provide firm grounds for the development of innovative therapeutic intervention strategies. ..O (.) '-" .+ 4U 4.' .U- 0_0 ..
  34. REAL TIME DETECTION OF BACTERIA IN PLATELET CONCENTRATES
    Boris Rotman; Fiscal Year: 2004
    ..Other potential applications of the bacteriologic biosensor include: diagnostics, environmental surveillance, food and beverage monitoring, and sterility testing. ..
  35. LOW-COST BIOSENSOR FOR REAL-TIME DIAGNOSIS OF BACTEREMIA
    Boris Rotman; Fiscal Year: 2004
    ..Other potential commercial applications of the bacteriologic biosensor include environmental surveillance, monitoring blood products intended for transfusion, food and beverage screening, and sterility testing. ..
  36. gC1q-R/p33: structure function and role on inflammation.
    Berhane Ghebrehiwet; Fiscal Year: 2009
    ..abstract_text> ..
  37. Engineered Spores as Fluorogenic Biological Indicators for Sterility Testing
    Boris Rotman; Fiscal Year: 2007
    ..To provide more rapid sterility assurance, BCR Diagnostics has developed unique living microorganisms that promptly send fluorescent light signals when the sterilization process is inadequate. [unreadable] [unreadable] [unreadable]..
  38. Natural mRNA Genetic Switches that Bind Metabolites
    Ronald Breaker; Fiscal Year: 2006
    ..These findings will aid in the discovery of new riboswitches and will provide a solid foundation for the generation of designer genetic control elements based on RNA. ..
  39. LTQ Orbitrap tandem mass spectrometer
    Catherine Fenselau; Fiscal Year: 2007
    ..This commercially available, technologically sophisticated instrument will support meritorious projects on a shared use, highly cost-effective basis, and foster multidisciplinary interaction. [unreadable] [unreadable] [unreadable]..