Genomes and Genes
Summary: A form-genus of spherical to rod-shaped CYANOBACTERIA in the order Chroococcales. They contain THYLAKOIDS and are found in a wide range of habitats.
Publications274 found, 100 shown here
- Fine-scale distribution patterns of Synechococcus ecological diversity in microbial mats of Mushroom Spring, Yellowstone National ParkEric D Becraft
Department of Land Resources and Environmental Sciences, Montana State University, 334 Leon Johnson Hall, Bozeman, MT 59715, USA
Appl Environ Microbiol 77:7689-97. 2011..protein-encoding genes have identified putative ecological species of unicellular cyanobacteria in the genus Synechococcus, which are specialized to 60°C but not 65°C in Mushroom Spring microbial mats...
- Rapid diversification of coevolving marine Synechococcus and a virusMarcia F Marston
Department of Biology and Marine Biology, Roger Williams University, Bristol, RI 02809, USA
Proc Natl Acad Sci U S A 109:4544-9. 2012..the potential for extensive antagonistic coevolution between the ecologically important marine cyanobacterium Synechococcus and a lytic virus. In a 6-mo-long replicated chemostat experiment, Synechococcus sp...
- Genome reduction by deletion of paralogs in the marine cyanobacterium ProchlorococcusHaiwei Luo
Department of Biological Sciences, University of South Carolina, SC, USA
Mol Biol Evol 28:2751-60. 2011..marine cyanobacterial genus Prochlorococcus have smaller genome sizes than those of the closely related genus Synechococcus. In order to test whether loss of protein-coding genes has contributed to genome size reduction in ..
- Metabolic and transcriptomic phenotyping of inorganic carbon acclimation in the Cyanobacterium Synechococcus elongatus PCC 7942Doreen Schwarz
Universitat Rostock, Institut Biowissenschaften, Pflanzenphysiologie, D 18059 Rostock, Germany
Plant Physiol 155:1640-55. 2011..Using Synechococcus elongatus PCC 7942, we characterized metabolic and transcriptomic changes in cells that had been shifted from ..
- Microarray analysis of phosphate regulation in the marine cyanobacterium Synechococcus sp. WH8102Sasha G Tetu
Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, New South Wales, Australia
ISME J 3:835-49. 2009..To observe how these organisms cope with P starvation, we constructed a full genome microarray for Synechococcus sp...
- A sequestration feedback determines dynamics and temperature entrainment of the KaiABC circadian clockChristian Brettschneider
Institute for Theoretical Biology, Humboldt Universitat zu Berlin, Berlin, Germany
Mol Syst Biol 6:389. 2010The circadian rhythm of the cyanobacterium Synechococcus elongatus is controlled by three proteins, KaiA, KaiB, and KaiC...
- Patterns and implications of gene gain and loss in the evolution of ProchlorococcusGregory C Kettler
Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
PLoS Genet 3:e231. 2007....
- Heterologous expression of Alteromonas macleodii and Thiocapsa roseopersicina [NiFe] hydrogenases in Synechococcus elongatusPhilip D Weyman
Department of Synthetic Biology and Bioenergy, The J Craig Venter Institute, Rockville, Maryland, United States of America
PLoS ONE 6:e20126. 2011..genes in the gene operon of HynSL were cloned in a vector with an IPTG-inducible promoter and introduced into Synechococcus elongatus PCC7942. The hydrogenase protein was expressed at the correct size upon induction with IPTG...
- Modular synthase-encoding gene involved in α-olefin biosynthesis in Synechococcus sp. strain PCC 7002Daniel Mendez-Perez
Department of Chemical and Biological Engineering, University of Wisconsin Madison, 1415 Engineering Dr, Madison, WI 53706, USA
Appl Environ Microbiol 77:4264-7. 2011A gene involved in the production of medium-chain α-olefins was identified in the cyanobacterium Synechococcus sp. strain PCC 7002...
- Light history influences the response of the marine cyanobacterium Synechococcus sp. WH7803 to oxidative stressNicolas Blot
UPMC Universite Paris 06, Station Biologique, 29680 Roscoff, France
Plant Physiol 156:1934-54. 2011Marine Synechococcus undergo a wide range of environmental stressors, especially high and variable irradiance, which may induce oxidative stress through the generation of reactive oxygen species (ROS)...
- Coastal strains of marine Synechococcus species exhibit increased tolerance to copper shock and a distinctive transcriptional response relative to those of open-ocean strainsRhona K Stuart
Scripps Institute of Oceanography, University of California, San Diego, La Jolla, 92093, USA
Appl Environ Microbiol 75:5047-57. 2009..By using growth assays of phylogenetically divergent clades, we found that coastal strains of marine Synechococcus species were more tolerant to copper shock than open-ocean strains...
- Intermolecular associations determine the dynamics of the circadian KaiABC oscillatorXiming Qin
Departments of Biological Sciences and Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA
Proc Natl Acad Sci U S A 107:14805-10. 2010..Therefore, we report here dynamics of interaction of KaiA and KaiB with KaiC that determine the period and amplitude of this in vitro oscillator...
- Ni uptake and limitation in marine Synechococcus strainsChristopher L Dupont
Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, USA
Appl Environ Microbiol 74:23-31. 2008Ni accumulation and utilization were studied in two strains of marine Synechococcus, isolated from both coastal (CC9311; clade I) and open-ocean (WH8102; clade III) environments, for which complete genome sequences are available...
- Oscillations in supercoiling drive circadian gene expression in cyanobacteriaVikram Vijayan
Graduate Program in Systems Biology, Howard Hughes Medical Institute, Harvard Faculty of Arts and Sciences Center for Systems Biology, Departments of Molecular and Cellular Biology and Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA
Proc Natl Acad Sci U S A 106:22564-8. 2009The cyanobacterium Synechococcus elongatus PCC 7942 exhibits oscillations in mRNA transcript abundance with 24-h periodicity under continuous light conditions...
- Cryptic diversity of the symbiotic cyanobacterium Synechococcus spongiarum among sponge hostsPatrick M Erwin
Department of Biology, University of Alabama at Birmingham, Birmingham, AL 35294 1170, USA
Mol Ecol 17:2937-47. 2008..The unicellular cyanobacterium Synechococcus spongiarum is the most prevalent photosynthetic symbiont in marine sponges and inhabits taxonomically diverse ..
- Spatially ordered dynamics of the bacterial carbon fixation machineryDavid F Savage
Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA
Science 327:1258-61. 2010..Thus, cyanobacteria use the cytoskeleton to control the spatial arrangement of carboxysomes and to optimize the metabolic process of carbon fixation...
- Widespread metabolic potential for nitrite and nitrate assimilation among Prochlorococcus ecotypesAdam C Martiny
Department of Earth System Science and Ecology, University of California, Irvine, CA 92697, USA
Proc Natl Acad Sci U S A 106:10787-92. 2009..genes are characterized by low GC content, form a separate phylogenetic clade most closely related to marine Synechococcus, and are located in a different genomic region compared with an orthologous cluster found in marine ..
- Regulation of nif gene expression and the energetics of N2 fixation over the diel cycle in a hot spring microbial matAnne Soisig Steunou
Department of Plant Biology, The Carnegie Institution, Stanford University, Stanford, CA, USA
ISME J 2:364-78. 2008..We analyzed the levels of nif transcripts of Synechococcus ecotypes, NifH subunit and nitrogenase activity over the diel cycle in the microbial mat of an alkaline hot ..
- Diel variations in carbon metabolism by green nonsulfur-like bacteria in alkaline siliceous hot spring microbial mats from Yellowstone National ParkMarcel T J van der Meer
Department of Marine Biogeochemistry and Toxicology, The Royal Netherlands Institute for Sea Research, P O Box 59, 1790 AB Den Burg Texel, The Netherlands
Appl Environ Microbiol 71:3978-86. 2005..In addition, we observed direct incorporation of [13C]acetate into GNSLB lipids in the morning. This suggests that GNSLB also have a potential for photoheterotrophy in situ...
- Intersubunit signaling in glutamate-1-semialdehyde-aminomutaseJ Stetefeld
Department of Structural Biology and M E Müller Institute for Structural Biology, Biozentrum Universität Basel, Klingelbergstrasse 70, 4056 Basel, Switzerland
Proc Natl Acad Sci U S A 103:13688-93. 2006..Together, they form a molecular switch in which the cofactor acts as a central signal transmitter linking the subunit interface with the gating loop...
- Functional and structural characterization of the 2/2 hemoglobin from Synechococcus sp. PCC 7002Nancy L Scott
Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
Biochemistry 49:7000-11. 2010Cyanobacterium Synechococcus sp. PCC 7002 contains a single gene (glbN) coding for GlbN, a protein of the 2/2 hemoglobin lineage...
- Cyanobacterial daily life with Kai-based circadian and diurnal genome-wide transcriptional control in Synechococcus elongatusHiroshi Ito
Division of Advanced Sciences, Ochadai Academic Production, Ochanomizu University, 2 1 1 Ohtsuka, Bunkyo, Tokyo, 112 8610, Japan
Proc Natl Acad Sci U S A 106:14168-73. 2009In the unicellular cyanobacterium Synechococcus elongatus PCC 7942, essentially all promoter activities are under the control of the circadian clock under continuous light (LL) conditions...
- Influence of molecular resolution on sequence-based discovery of ecological diversity among Synechococcus populations in an alkaline siliceous hot spring microbial matMelanie C Melendrez
Land Resources and Environmental Science, Montana State University, Bozeman, Montana, USA
Appl Environ Microbiol 77:1359-67. 2011..internal transcribed spacer regions may not have enough genetic resolution to define all ecologically distinct Synechococcus populations (ecotypes) inhabiting alkaline, siliceous hot spring microbial mats...
- Large improvements in MS/MS-based peptide identification rates using a hybrid analysisWilliam R Cannon
Computational Biology and Bioinformatics Group, Pacific Northwest National Laboratory, Richland, Washington 99352, United States
J Proteome Res 10:2306-17. 2011..We applied this approach to proteomics analysis of Synechococcus sp...
- Untargeted metabolic footprinting reveals a surprising breadth of metabolite uptake and release by Synechococcus sp. PCC 7002Richard Baran
Life Sciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, MS 84R0171, Berkeley, California 94720, United States
Mol Biosyst 7:3200-6. 2011..to systematically evaluate the uptake and release of metabolites between a model marine cyanobacterium Synechococcus sp. PCC 7002 and different growth media...
- Selection in coastal Synechococcus (cyanobacteria) populations evaluated from environmental metagenomesVera Tai
Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, United States of America
PLoS ONE 6:e24249. 2011..of a gene, from environmental metagenomes sequenced using 454 technology of flow-sorted populations of marine Synechococcus, the dominant cyanobacteria in coastal environments...
- Multi-locus sequence analysis, taxonomic resolution and biogeography of marine SynechococcusSophie Mazard
School of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry, UK
Environ Microbiol 14:372-86. 2012..gene do not provide sufficient molecular resolution to identify spatially structured populations of marine Synechococcus, or 'ecotypes' adapted to distinct ecological niches...
- Genome sequence of Synechococcus CC9311: Insights into adaptation to a coastal environmentBrian Palenik
Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA 92093, USA
Proc Natl Acad Sci U S A 103:13555-9. 2006..Despite these differences, cyanobacteria from the genus Synechococcus are important primary producers in both types of ecosystems...
- Genome sequences of siphoviruses infecting marine Synechococcus unveil a diverse cyanophage group and extensive phage-host genetic exchangesSijun Huang
State Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen, China
Environ Microbiol 14:540-58. 2012..genome sequences of siphoviruses (S-CBS1, S-CBS2, S-CBS3 and S-CBS4) that infect four different marine Synechococcus strains...
- Circadian transcriptional regulation by the posttranslational oscillator without de novo clock gene expression in SynechococcusNorimune Hosokawa
Department of Electrical Engineering and Biological Science, Waseda University, Shinjuku, Tokyo 162 8480, Japan
Proc Natl Acad Sci U S A 108:15396-401. 2011..In the unicellular obligately photoautotrophic cyanobacterium Synechococcus elongatus PCC 7942, essentially all promoter activities are controlled by the KaiABC-based clock under ..
- Non-coding RNAs in marine Synechococcus and their regulation under environmentally relevant stress conditionsGregor Gierga
Faculty of Biology, University of Freiburg, Schaenzlestrasse 1, Freiburg, Germany
ISME J 6:1544-57. 2012..b>Synechococcus sp...
- PtrA is required for coordinate regulation of gene expression during phosphate stress in a marine SynechococcusMartin Ostrowski
Department of Biological Sciences, University of Warwick, Coventry, UK
ISME J 4:908-21. 2010..system PhoBR (SYNW0947, SYNW0948) in the regulation of P transport and metabolism in the marine cyanobacterium Synechococcus sp. WH8102...
- HtpG, the prokaryotic homologue of Hsp90, stabilizes a phycobilisome protein in the cyanobacterium Synechococcus elongatus PCC 7942Takeshi Sato
Department of Biochemistry and Molecular Biology, Saitama University, Saitama 338 8570, Japan
Mol Microbiol 76:576-89. 2010..We obtained evidence that HtpG interacts with linker polypeptides of phycobilisome in the cyanobacterium Synechococcus elongatus PCC 7942. In an htpG mutant, the 30 kDa rod linker polypeptide was reduced...
- Roles of xanthophyll carotenoids in protection against photoinhibition and oxidative stress in the cyanobacterium Synechococcus sp. strain PCC 7002Yuehui Zhu
Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA
Arch Biochem Biophys 504:86-99. 2010b>Synechococcus sp...
- Studies on the role of HtpG in the tetrapyrrole biosynthesis pathway of the cyanobacterium Synechococcus elongatus PCC 7942Satoru Watanabe
Department of Bioscience, Tokyo University of Agriculture, Sakuragaoka 1 1 1, Setagaya Ku, Tokyo 156 8502, Japan
Biochem Biophys Res Commun 352:36-41. 2007In cyanobacterium Synechococcus elongatus PCC 7942, we observed that htpG-overexpression caused remarkable growth inhibition. In addition, subcellular fractionation experiments showed that HtpG was localized in the membrane fraction...
- The role of lipids in photosystem IINaoki Mizusawa
Department of Life Sciences, Graduate School of Arts and Sciences, University of Tokyo, Meguro ku, Tokyo, Japan
Biochim Biophys Acta 1817:194-208. 2012..This review summarizes our present understanding of the biochemical and physiological roles of lipids in photosynthesis, with a special focus on PSII. This article is part of a Special Issue entitled: Photosystem II...
- Rerouting carbon flux to enhance photosynthetic productivityDaniel C Ducat
Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA
Appl Environ Microbiol 78:2660-8. 2012..We demonstrate the efficient production of sucrose from a cyanobacterial species, Synechococcus elongatus, heterologously expressing a symporter of protons and sucrose (cscB)...
- Elucidating essential role of conserved carboxysomal protein CcmN reveals common feature of bacterial microcompartment assemblyJames N Kinney
Department of Energy Joint Genome Institute, Walnut Creek, California 94598, USA
J Biol Chem 287:17729-36. 2012....
- Functional characterization of a naturally occurring trans-splicing intein from Synechococcus elongatus in a mammalian cell systemLinjie Chen
Institute of Biochemistry, College of Life Sciences, Zijingang Campus, Zhejiang University, Hangzhou, Zhejiang 310058, China
Anal Biochem 407:180-7. 2010..a naturally occurring split mini-DnaE intein capable of protein trans-splicing in the cyanobacterium Synechococcus elongatus (Sel DnaE intein). Sel DnaE intein is homologous to Synechocystissp...
- Transcript profiling reveals new insights into the acclimation of the mesophilic fresh-water cyanobacterium Synechococcus elongatus PCC 7942 to iron starvationAnke Nodop
Lehrstuhl für Molekulare Zellphysiologie, Universitat Bielefeld, D 33615 Bielefeld, Germany
Plant Physiol 147:747-63. 2008The regulatory network for acclimation of the obligate photoautotrophic fresh water cyanobacterium Synechococcus elongatus PCC 7942 to iron (Fe) limitation was studied by transcript profiling with an oligonucleotide whole genome DNA ..
- Temporal variation of Synechococcus clades at a coastal Pacific Ocean monitoring siteVera Tai
Marine Biology Research Division, Scripps Institution of Oceanography, University of California, La Jolla, San Diego, CA 92093 0202, USA
ISME J 3:903-15. 2009Marine cyanobacteria from the genus Synechococcus are found throughout the world's oceans and are important contributors to global primary productivity and carbon cycling...
- Unraveling the genomic mosaic of a ubiquitous genus of marine cyanobacteriaAlexis Dufresne
Université Paris 6 and CNRS, UMR 7144, Station Biologique, 29682 Roscoff, France
Genome Biol 9:R90. 2008The picocyanobacterial genus Synechococcus occurs over wide oceanic expanses, having colonized most available niches in the photic zone...
- Phosphorus deprivation responses and phosphonate utilization in a thermophilic Synechococcus sp. from microbial matsMelissa M Adams
Carnegie Institution for Science, Department of Plant Biology, Stanford University, Stanford, CA 94305, USA
J Bacteriol 190:8171-84. 2008The genomes of two closely related thermophilic cyanobacterial isolates, designated Synechococcus isolate OS-A and Synechococcus isolate OS-B', from the microbial mats of Octopus Spring (Yellowstone National Park) have been sequenced...
- No transcription-translation feedback in circadian rhythm of KaiC phosphorylationJun Tomita
Division of Biological Science, Graduate School of Science, Nagoya University, and Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Furo cho, Chikusa ku, Nagoya 464 8602, Japan
Science 307:251-4. 2005..In the cyanobacterium Synechococcus elongatus, the essential clock protein KaiC is proposed to form this type of transcriptional negative feedback...
- Global phylogeography of marine Synechococcus and Prochlorococcus reveals a distinct partitioning of lineages among oceanic biomesKatrin Zwirglmaier
Department of Biological Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK
Environ Microbiol 10:147-61. 2008Marine cyanobacteria of the genera Prochlorococcus and Synechococcus are important contributors to global primary production occupying a key position at the base of marine food webs...
- Phylogenetic diversity of sequences of cyanophage photosynthetic gene psbA in marine and freshwatersC Chenard
Department of Earth and Ocean Sciences, University of British Columbia, 1461 6270 University Blvd, Vancouver, BC V6T1Z4, Canada
Appl Environ Microbiol 74:5317-24. 2008Many cyanophage isolates which infect the marine cyanobacteria Synechococcus spp. and Prochlorococcus spp. contain a gene homologous to psbA, which codes for the D1 protein involved in photosynthesis...
- Sensing of inorganic carbon limitation in Synechococcus PCC7942 is correlated with the size of the internal inorganic carbon pool and involves oxygenFiona J Woodger
Molecular Plant Physiology Group, Research School of Biological Sciences, Australian National University, Canberra, Australian Capital Territory 0200, Australia
Plant Physiol 139:1959-69. 2005..interested in the regulation of the CO2-concentrating mechanism (CCM) in the model freshwater cyanobacterium Synechococcus sp. strain PCC7942 in response to Ci limitation; however, the nature of Ci sensing is poorly understood...
- Phylogenetic analyses of cyanobacterial genomes: quantification of horizontal gene transfer eventsOlga Zhaxybayeva
Genome Atlantic and Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia B3H 1X5, Canada
Genome Res 16:1099-108. 2006..However, in interphylum as compared to intraphylum transfers, the proportion of metabolic (operational) gene transfers increases, while the proportion of informational gene transfers decreases...
- Variability in protist grazing and growth on different marine Synechococcus isolatesJude K Apple
1900 Shannon Point Road, Shannon Point Marine Center, Western Washington University, Anacortes, WA 98221, USA
Appl Environ Microbiol 77:3074-84. 2011Grazing mortality of the marine phytoplankton Synechococcus is dominated by planktonic protists, yet rates of consumption and factors regulating grazer-Synechococcus interactions are poorly understood...
- How a cyanobacterium tells timeGuogang Dong
Center for Biological Clocks Research and Department of Biology, Texas A and M University, College Station, TX 77843 3258, United States
Curr Opin Microbiol 11:541-6. 2008The cyanobacterium Synechococcus elongatus builds a circadian clock on an oscillator composed of three proteins, KaiA, KaiB, and KaiC, which can recapitulate a circadian rhythm of KaiC phosphorylation in vitro...
- High-throughput functional analysis of the Synechococcus elongatus PCC 7942 genomeC Kay Holtman
Department of Biology, Texas A and M University, College Station, TX 77843 3258, USA
DNA Res 12:103-15. 2005b>Synechococcus elongatus PCC 7942 was the first cyanobacterial strain to be reliably transformed by exogenously added DNA and has become the model organism for cyanobacterial circadian rhythms. With a small genome (2...
- Characterization of two cytochrome oxidase operons in the marine cyanobacterium Synechococcus sp. PCC 7002: inactivation of ctaDI affects the PS I:PS II ratioChristopher T Nomura
Department of Biochemistry and Molecular Biology, Center for Biomolecular Structure and Function, The Pennsylvania State University, University Park, PA 16802, USA
Photosynth Res 87:215-28. 2006..In this study we have cloned and sequenced two gene clusters from the marine cyanobacterium Synechococcus sp. PCC 7002 that potentially encode heme-copper cytochrome oxidases...
- Iron stress genes in marine Synechococcus and the development of a flow cytometric iron stress assayAdam R Rivers
Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA
Environ Microbiol 11:382-96. 2009Marine Synechococcus are frequently found in environments where iron (Fe) is a limiting nutrient...
- Photosystem I gene cassettes are present in marine virus genomesItai Sharon
Faculty of Biology, Technion Israel Institute of Technology, Haifa 32000, Israel
Nature 461:258-62. 2009Cyanobacteria of the Synechococcus and Prochlorococcus genera are important contributors to photosynthetic productivity in the open oceans...
- Three major output pathways from the KaiABC-based oscillator cooperate to generate robust circadian kaiBC expression in cyanobacteriaYasuhito Taniguchi
Division of Biological Science, Graduate School of Science, Nagoya University, Nagoya 464 8602, Japan
Proc Natl Acad Sci U S A 107:3263-8. 2010Circadian kaiBC expression in the cyanobacterium Synechococcus elongatus PCC 7942 is generated by temporal information transmission from the KaiABC-based circadian oscillator to RpaA, a putative transcriptional factor, via the SasA-..
- Expression of genes in cyanobacteria: adaptation of endogenous plasmids as platforms for high-level gene expression in Synechococcus sp. PCC 7002Yu Xu
Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA
Methods Mol Biol 684:273-93. 2011b>Synechococcus sp. PCC 7002 is an ideal model cyanobacterium for functional genomics and biotechnological applications through metabolic engineering...
- Coordinate up-regulation of carotenoid biosynthesis as a response to light stress in Synechococcus PCC7942Lutz Schäfer
Molecular Biosciences 213, J W Goethe Universitat, PO Box 111932, D 60054 Frankfurt M, Germany
Plant Cell Environ 29:1349-56. 2006Carotenoid biosynthesis is up-regulated by strong light in the cyanobacterium Synechococcus. By blocking off the pathway at the level of phytoene conversion, light-dependent accumulation of phytoene was observed...
- Cyanophage tRNAs may have a role in cross-infectivity of oceanic Prochlorococcus and Synechococcus hostsHagay Enav
Faculty of Biology, Technion Israel Institute of Technology, Haifa, Israel
ISME J 6:619-28. 2012Marine cyanobacteria of the genera Prochlorococcus and Synechococcus are the most abundant photosynthetic prokaryotes in oceanic environments, and are key contributors to global CO(2) fixation, chlorophyll biomass and primary production...
- Synchronization of circadian oscillation of phosphorylation level of KaiC in vitroTetsuro Nagai
Department of Computational Science and Engineering, Nagoya University, Nagoya, Japan
Biophys J 98:2469-77. 2010..This mechanism of synchronization should be important in vivo for the persistent oscillation when Kai proteins are synthesized at random timing in cyanobacterial cells...
- Structural basis for the regulation of NtcA-dependent transcription by proteins PipX and PIIJosé L Llácer
Instituto de Biomedicina de Valencia Consejo Superior de Investigaciones Cientificas, Centro de Investigación Biomédica en Red de Enfermedades Raras, Jaime Roig 11, Valencia 46010, Spain
Proc Natl Acad Sci U S A 107:15397-402. 2010..We determine for the cyanobacteria Synechococcus elongatus the crystal structures of the PII-PipX and PipX-NtcA complexes and of NtcA in active and inactive ..
- Over-expression of the β-carboxysomal CcmM protein in Synechococcus PCC7942 reveals a tight co-regulation of carboxysomal carbonic anhydrase (CcaA) and M58 contentBenedict M Long
Molecular Plant Physiology, Plant Science Division, Research School of Biology, College of Medicine, Biology and Environment, The Australian National University, Canberra, ACT, Australia
Photosynth Res 109:33-45. 2011..We have over-expressed both M35 and M58 in the β-cyanobacterium Synechococcus PCC7942...
- Transcriptional regulation of the CO2-concentrating mechanism in a euryhaline, coastal marine cyanobacterium, Synechococcus sp. Strain PCC 7002: role of NdhR/CcmRFiona J Woodger
Molecular Plant Physiology Group, Research School of Biological Sciences, Australian National University, P O Box 475, Canberra, ACT 0200, Australia
J Bacteriol 189:3335-47. 2007..Inactivation of the single gene (termed ccmR) from this variable cluster in the euryhaline (coastal) strain Synechococcus sp. strain PCC 7002 led to constitutive expression of a high-affinity CCM...
- Temporal orchestration of glycogen synthase (GlgA) gene expression and glycogen accumulation in the oceanic picoplanktonic cyanobacterium Synechococcus sp. strain WH8103Michael Wyman
Biological and Environmental Sciences, School of Natural Sciences, University of Stirling, United Kingdom
Appl Environ Microbiol 78:4744-7. 2012Glycogen is accumulated during the latter half of the diel cycle in Synechococcus sp. strain WH8103 following a midday maximum in glgA (encoding glycogen synthase) mRNA abundance...
- The regulatory factor SipA provides a link between NblS and NblR signal transduction pathways in the cyanobacterium Synechococcus sp. PCC 7942Paloma Salinas
Division de Genetica, Universidad de Alicante, Apartado 99, E 03080 Alicante, Spain
Mol Microbiol 66:1607-19. 2007..When subjected to nutrient and high light stress, Synechococcus sp...
- Role of the Synechococcus PCC 7942 nitrogen regulator protein PipX in NtcA-controlled processesJavier Espinosa
Division de Genetica, Universidad de Alicante, Apartado 99, E 03080 Alicante, Spain
Microbiology 153:711-8. 2007The Synechococcus sp. PCC 7942 nitrogen regulator PipX interacts in a 2-oxoglutarate-dependent manner with the global nitrogen transcription factor NtcA and the signal transduction protein P(II)...
- Dynamics of RpaB-promoter interaction during high light stress, revealed by chromatin immunoprecipitation (ChIP) analysis in Synechococcus elongatus PCC 7942Mitsumasa Hanaoka
Laboratory of Molecular Genetics, Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1 1 1 Yayoi, Bunkyo ku, Tokyo 113 0032, Japan
Plant J 56:327-35. 2008..Thus, in regulation of high light-inducible genes, we suggest that RpaB functions as a repressor under normal light conditions, and that high light conditions result in release of the repression...
- Negative control of the high light-inducible hliA gene and implications for the activities of the NblS sensor kinase in the cyanobacterium Synechococcus elongatus strain PCC 7942Anthony D Kappell
Department of Biology, The University of Texas at Arlington, Arlington, TX 76019, USA
Arch Microbiol 186:403-13. 2006The hliA gene of the cyanobacterium Synechococcus elongatus PCC 7942 is known to be upregulated by high-intensity light through the activity of the NblS sensor kinase...
- Effects of spontaneous mutations in PipX functions and regulatory complexes on the cyanobacterium Synechococcus elongatus strain PCC 7942Javier Espinosa
Division de Genetica, Universidad de Alicante, Apartado 99, E 03080 Alicante, Spain
Microbiology 156:1517-26. 2010In Synechococcus elongatus sp. PCC 7942, PipX forms complexes with P(II), a protein found in all three domains of life as an integrator of signals of the nitrogen and carbon balance, and with the cyanobacterial nitrogen regulator NtcA...
- A novel allele of kaiA shortens the circadian period and strengthens interaction of oscillator components in the cyanobacterium Synechococcus elongatus PCC 7942You Chen
Department of Biology, Texas A and M University, College Station, Texas 77843 3258, USA
J Bacteriol 191:4392-400. 2009The basic circadian oscillator of the unicellular fresh water cyanobacterium Synechococcus elongatus PCC 7942, the model organism for cyanobacterial circadian clocks, consists of only three protein components: KaiA, KaiB, and KaiC...
- [The first protein map of Synechococcus sp. strain PCC 7942]O A Koksharova
Mikrobiologiia 75:765-74. 2006The first protein map was developed of Synechococcus sp...
- Circadian timekeeping in Neurospora crassa and Synechococcus elongatusSusan K Crosthwaite
University of Manchester, U K
Essays Biochem 49:37-51. 2011At first, the saprophytic eukaryote Neurospora crassa and the photosynthetic prokaryote Synechococcus elongatus may seem to have little in common...
- Characterization of dnaJ multigene family in the cyanobacterium Synechococcus elongatus PCC 7942Masumi Sato
Department of Bioscience, Tokyo University of Agriculture, Tokyo, Japan
Biosci Biotechnol Biochem 71:1021-7. 2007The genome of the cyanobacterium Synechococcus elongatus PCC 7942 contains four dnaJ homologs, which are classified into three types based on domain structure...
- RbcX can function as a rubisco chaperonin, but is non-essential in Synechococcus PCC7942Daniel Emlyn-Jones
Molecular Plant Physiology, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
Plant Cell Physiol 47:1630-40. 2006..In Synechococcus PCC7942, however, rbcX is located >100 kb away from the rbcLS operon, providing an opportunity to examine the ..
- Mechanism of 2-oxoglutarate signaling by the Synechococcus elongatus PII signal transduction proteinOleksandra Fokina
Interfakultäres Institut für Mikrobiologie und Infektionsmedizin der Eberhard Karls Universität Tübingen, Auf der Morgenstelle 28, 72076 Tubingen, Germany
Proc Natl Acad Sci U S A 107:19760-5. 2010..Here we show structures of the Synechococcus elongatus P(II) protein in complex with ATP, Mg(2+), and 2-OG, which clarify how 2-OG affects P(II)-NAGK ..
- Ecological advantages from light adaptation and heterotrophic-like behavior in Synechococcus harvested from the Gulf of Trieste (Northern Adriatic Sea)Alessandro Paoli
Department of Biological Oceanography, National Institute of Oceanography and Experimental Geophysics, Santa Croce, Trieste, Italy
FEMS Microbiol Ecol 64:219-29. 2008..on a picocyanobacterial mixed culture harvested from the Gulf of Trieste (Northern Adriatic) and identified as Synechococcus spp. both by transmission electron microscopy observations, biliprotein composition and molecular analyses...
- A novel signal transduction protein P(II) variant from Synechococcus elongatus PCC 7942 indicates a two-step process for NAGK-P(II) complex formationOleksandra Fokina
Interfakultäres Institut für Mikrobiologie und Infektionsmedizin der Eberhard Karls Universität Tübingen, Auf der Morgenstelle 28, 72076 Tubingen, Germany
J Mol Biol 399:410-21. 2010..In the cyanobacterium Synechococcus elongatus PCC 7942, P(II) binds ATP and 2-oxoglutarate (2-OG) in a synergistic manner, with the ATP binding ..
- Expression of foreign type I ribulose-1,5-bisphosphate carboxylase/ oxygenase (EC 184.108.40.206) stimulates photosynthesis in cyanobacterium Synechococcus PCC7942 cellsT Iwaki
Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Gakuen cho 1 2, 599 8231 Osaka, Sakai, Japan
Photosynth Res 88:287-97. 2006A reporter gene assay revealed that promoters derived from Synechococcus PCC7942 (S.7942) psbAI and Synechocystis PCC6803 (S.6803) psbAII were suitable for the expression of foreign ribulose-bisphosphate carboxylase (RuBisCO; EC 4.1.1...
- Large reallocations of carbon, nitrogen, and photosynthetic reductant among phycobilisomes, photosystems, and Rubisco during light acclimation in Synechococcus elongatus strain PCC7942 are constrained in cells under low environmental inorganic carbonTyler D B MacKenzie
Department of Biology, University of New Brunswick, Fredericton, New Brunswick E3B 6E1, Canada
Arch Microbiol 183:190-202. 2005b>Synechococcus elongatus strain PCC7942 cells were grown in high or low environmental concentrations of inorganic C (high-C(i), low-C(i)) and subjected to a light shift from 50 micromol m(-2) s(-1) to 500 micromol m(-2) s(-1)...
- Control of ribosome synthesis during the cell division cycles of E. coli and SynechococcusYukio Asato
University of Massachusetts Dartmouth, N Dartmouth, Massachusetts 02747, USA
Curr Issues Mol Biol 7:109-17. 2005..In Synechococcus, a photoautotroph, ribosome synthesis occurs early in the cell cycle as programmed events under conditions ..
- Chromatophore genome sequence of Paulinella sheds light on acquisition of photosynthesis by eukaryotesEva C M Nowack
Botanical Institute, University of Cologne, Gyrhofstr 15, D 50931 Köln, Germany
Curr Biol 18:410-8. 2008..To clarify metabolic capabilities of the chromatophore and its state of integration into the host, we present here the complete genome sequence of the chromatophore...
- The rbcX gene product promotes the production and assembly of ribulose-1,5-bisphosphate carboxylase/oxygenase of Synechococcus sp. PCC7002 in Escherichia coliTakuo Onizuka
Biological Science Laboratories, Toray Research Center, Inc, 1111 Tebiro, Kamakura, Kanagawa, 248 8555 Japan
Plant Cell Physiol 45:1390-5. 2004The operon encoding ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) in the cyanobacterium Synechococcus sp. PCC7002 contains three rbc genes, rbcL, rbcX and rbcS, in this order...
- Carbohydrate metabolism in mutants of the cyanobacterium Synechococcus elongatus PCC 7942 defective in glycogen synthesisEiji Suzuki
Department of Biological Production, Faculty of Bioresource Sciences, Akita Prefectural University, Akita 010 0195, Japan
Appl Environ Microbiol 76:3153-9. 2010..Mutants defective in each of these enzymes in Synechococcus elongatus PCC 7942 were constructed and characterized...
- ApcD is necessary for efficient energy transfer from phycobilisomes to photosystem I and helps to prevent photoinhibition in the cyanobacterium Synechococcus sp. PCC 7002Chunxia Dong
State Key Lab of Protein and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing 100871, China
Biochim Biophys Acta 1787:1122-8. 2009..In this study the quantum efficiency of excitation energy transfer from PBS to PS I in the cyanobacterium Synechococcus sp...
- Whole-genome microarray analyses of Synechococcus-Vibrio interactionsVera Tai
Marine Biology Research Division, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA 92093 0202, USA
Environ Microbiol 11:2698-709. 2009..whole-genome microarray analyses were used and revealed that several major metabolic pathways were affected in Synechococcus sp. WH8102, a model phototroph, when grown with Vibrio parahaemolyticus, a model heterotroph...
- Use of inorganic and organic nitrogen by Synechococcus spp. and diatoms on the west Florida shelf as measured using stable isotope probingBoris Wawrik
Department of Botany and Microbiology, University of Oklahoma, Norman, Oklahoma 73019 4110, USA
Appl Environ Microbiol 75:6662-70. 2009..In this study we used (15)N SIP methodology to assess the use of different nitrogen substrates by Synechococcus spp. and diatoms on the west Florida shelf...
- Low taxon richness of bacterioplankton in high-altitude lakes of the eastern tibetan plateau, with a predominance of Bacteroidetes and Synechococcus sppPeng Xing
State Key Laboratory of Lake Science and Environment, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, East Beijing Road 73, Nanjing 210008, People s Republic of China
Appl Environ Microbiol 75:7017-25. 2009..Another characteristic of the investigated lakes was the predominance of Cyanobacteria (Synechococcus) and Bacteroidetes...
- The Calvin cycle in cyanobacteria is regulated by CP12 via the NAD(H)/NADP(H) ratio under light/dark conditionsMasahiro Tamoi
Department of Food and Nutrition, Faculty of Agriculture, Kinki University, Nakamachi, Nara 631 8505, Japan
Plant J 42:504-13. 2005In Synechococcus PCC7942 cells grown in the dark, the concentrations of NAD(H) and NADP(H) were 128+/-2.5 and 483+/-4.0 microm, respectively, while those in the cells under light conditions were 100+/-5.0 and 649+/-7...
- Biochemical bases of type IV chromatic adaptation in marine Synechococcus sppCraig Everroad
Center for Ecology and Evolution, Department of Biology, University of Oregon, Eugene, Oregon 97403, USA
J Bacteriol 188:3345-56. 2006..However, the chromophore compositions of these polypeptides are not altered. Some marine Synechococcus species strains, which possess two PE forms (PEI and PEII), carry out another type of CA (type IV), occurring ..
- Specific binding of D1 protein degradation products to the psbAI promoter in Synechococcus sp. strain PCC 7942Christian Stelljes
Molekulare Pflanzenphysiologie, Universitat Bremen, Leobener Str, 28359 Bremen, Germany
J Bacteriol 189:1722-6. 2007..Additionally, C-terminal fragments of the D1 protein bind to a sequence with similarity to isiB, a gene which encodes a flavodoxin-like protein...
- Selection and characterization of cyanophage resistance in marine Synechococcus strainsLauren I Stoddard
Department of Biology, Roger Williams University, Bristol, RI 02809, USA
Appl Environ Microbiol 73:5516-22. 2007..Resistance to cooccurring cyanophages has been reported for natural communities of Synechococcus spp.; however, little is known about the nature of this resistance...
- UV-induced phycobilisome dismantling in the marine picocyanobacterium Synechococcus sp. WH8102Christophe Six
Station Biologique, UMR 7144 CNRS et Université Pierre et Marie Curie, B P 74, 29682, Roscoff Cedex, France
Photosynth Res 92:75-86. 2007The marine picocyanobacterium Synechococcus sp...
- A proteomic approach to the identification of the major virion structural proteins of the marine cyanomyovirus S-PM2Martha R J Clokie
Department of Infection, Immunity and Inflammation, Maurice Shock Medical Sciences Building, University of Leicester, Leicester LE1 9HN, UK
Microbiology 154:1775-82. 2008..The virus infects ecologically important cyanobacteria of the genus Synechococcus that make a substantial contribution to primary production in the oceans...
- Prevalence and evolution of core photosystem II genes in marine cyanobacterial viruses and their hostsMatthew B Sullivan
Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
PLoS Biol 4:e234. 2006..myoviruses and Prochlorococcus podoviruses, but could not be amplified from Prochlorococcus siphoviruses or Synechococcus podoviruses. Nearly all of the phages that encoded both psbA and psbD had broad host ranges...
- Artificially evolved Synechococcus PCC6301 Rubisco variants exhibit improvements in folding and catalytic efficiencyDina N Greene
Department of Biochemistry, Center for Fundamental and Applied Molecular Evolution, Emory University School of Medicine, Rollins Research Center, Atlanta, GA 30322, USA
Biochem J 404:517-24. 2007..Recently, the horizontal transfer of Calvin cycle genes (rbcL, rbcS and prkA) from cyanobacteria (Synechococcus PCC6301) to gamma-proteobacteria (Escherichia coli) was emulated in the laboratory...
- Genome sequence, structural proteins, and capsid organization of the cyanophage Syn5: a "horned" bacteriophage of marine synechococcusWelkin H Pope
Department of Biology, Massachusetts Institute of Technology, Cambridge MA 02139, USA
J Mol Biol 368:966-81. 2007Marine Synechococcus spp and marine Prochlorococcus spp are numerically dominant photoautotrophs in the open oceans and contributors to the global carbon cycle...
- Seasonal variations in virus-host populations in Norwegian coastal waters: focusing on the cyanophage community infecting marine Synechococcus sppRuth Anne Sandaa
University of Bergen, Department of Biology, P O Box 7800, N 5020 Bergen, Norway
Appl Environ Microbiol 72:4610-8. 2006..Using flow cytometry and real-time PCR, we focused in particular on one host-virus system: Synechococcus spp. and cyanophages...
- Two members of a network of putative Na+/H+ antiporters are involved in salt and pH tolerance of the freshwater cyanobacterium Synechococcus elongatusMaria Billini
Institute of Biology, National Centre for Scientific Research Demokritos, Aghia Paraskevi, 153 10 Athens, Greece
J Bacteriol 190:6318-29. 2008b>Synechococcus elongatus strain PCC 7942 is an alkaliphilic cyanobacterium that tolerates a relatively high salt concentration as a freshwater microorganism...
- Portal protein diversity and phage ecologyMatthew B Sullivan
Departments of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
Environ Microbiol 10:2810-23. 2008..Previous studies, focusing on myophages that infect the marine cyanobacterium Synechococcus, have used the coliphage T4 portal-protein-encoding homologue, gene 20 (g20), as a diversity marker...
- Structural insights into a circadian oscillatorCarl Hirschie Johnson
Department of Biological Sciences, Box 35 1634, Vanderbilt University, Nashville, TN 37235 1634, USA
Science 322:697-701. 2008..The conjunction of structural, biophysical, and biochemical approaches to this system reveals molecular mechanisms of biological timekeeping...
- Complete nucleotide sequence of the freshwater unicellular cyanobacterium Synechococcus elongatus PCC 6301 chromosome: gene content and organizationChieko Sugita
Center for Gene Research, Nagoya University, Chikusa, Nagoya 464 8602, Japan
Photosynth Res 93:55-67. 2007The entire genome of the unicellular cyanobacterium Synechococcus elongatus PCC 6301 (formerly Anacystis nidulans Berkeley strain 6301) was sequenced. The genome consisted of a circular chromosome 2,696,255 bp long...
- Hourglass model for a protein-based circadian oscillatorEldon Emberly
Physics Department, Simon Fraser University, Burnaby, British Columbia, Canada V5A 1S6
Phys Rev Lett 96:038303. 2006..Our results highlight the importance of collective assembly or disassembly of proteins in biochemical networks, and may help guide design of novel protein-based oscillators...
- Structural Biology of the S. elongatus Circadian ClockMartin Egli; Fiscal Year: 2013..We study the components of the biological clock in the prokaryotic cyanobacterium, Synechococcus elongatus, which programs many processes to conform optimally to the daily cycle, including photosynthesis, ..
- COORDINATION OF CIRCADIAN PHYSIOLOGY OF DIVERSE SPECIESDeborah Bell Pedersen; Fiscal Year: 2010..cores and shared data, a common process could be studied in 4 instructive model systems: the cyanobacterium Synechococcus, the fungus Neurospora, the chick pineal gland, and the rodent suprachiasmatic nucleus (SCN)...
- Circadian gating of cell division by the cyanobacterial oscillatorJOSEPH A POGLIANO; Fiscal Year: 2013..The circadian control of cell division in the cyanobacterium Synechococcus elongatus provides an elegant system in which to address questions that probe the interactions of the clock, ..
- Design Principals of Photobiological MetabolismDaniel C Ducat; Fiscal Year: 2012..To this end, I propose to examine the plasticity of electron flux from ferredoxin within the cyanobacterium Synechococcus elongatus PCC7942...
- Mathematical models of membrane biophysics and microbial locomotionGeorge F Oster; Fiscal Year: 2013..g. Flavobacteria), and (ii) the swimming of the cyanobacterium, Synechococcus. This work will be carried out in collaboration with the experimental laboratories of Professor D...
- THE PATHWAY THAT SETS THE CYANOBACTERIAL CIRCADIAN CLOCKSusan S Golden; Fiscal Year: 2013..The specific aims address the mechanisms of each of these aspects of biological timing in the cyanobacterium Synechococcus elongatus, the simplest model organism known to have a 24-h biological (circadian) clock...
- Structure of Circadian Clock Complexes from Cyanobacteria by Three Dimensional EMPhoebe L Stewart; Fiscal Year: 2010..and biochemical studies have identified three key clock proteins, KaiA, KaiB, and KaiC in the cyanobacterium Synechococcus elongatus...
- Regulation and Significance of Sustained Circadian OscillationsCarl Hirschie Johnson; Fiscal Year: 2013..Testing this hypothesis will take advantage of the unique capabilities of the eubacteria Synechococcus elongatus (cyanobacterium) and E...
- The properties and evolvability of the cyanobacterial circadian genetic networkRyan K Shultzaberger; Fiscal Year: 2013..probe the properties and evolution of the genetic network that underlies circadian rhythm in the cyanobacteria Synechococcus elongatus PCC 7942 to better understand the molecular mechanism of circadian regulation, its plasticity (..
- Coupling between Circadian Rhythms and Metaboilsm in CyanobacteriaMICHAEL RUST; Fiscal Year: 2013..biochemical measurements with experimentally-driven mathematically modeling in the bacterial model organism Synechococcus elongatus to study the interlocking relationships between clocks, metabolism, and organismal fitness...
- CHARACTERIZATION OF RHEUMATOID ANTIGENS IN CYANOBACTERIASHIRLEY KOVACS; Fiscal Year: 1991..identifying anti-RNP, anti-Sm, and anti-m3G "cap" reactivity indicate that the procaryotic cyanobacterium, Synechococcus leopoliensis, may be such a source...
- Tertiary Structures of Circadian Clock Proteins by NMRAndy LiWang; Fiscal Year: 2006..can be achieved by investigating the three-dimensional structures and dynamics of the clock proteins of Synechococcus elongatus, SasA, KaiA, KaiB and KaiC using nuclear magnetic resonance spectroscopy (NMR)...
- REGULATION OF BILIPROTEIN IN CYANOBACTERIADONALD BRYANT; Fiscal Year: 2002..Most of the proposed studies will be performed using Synechococcus sp...
- Screening for Chronotherapeutics Applied to Hypersomnia and Other Sleep DisordersCarl Johnson; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Novel ratiometric luminescence reporters for intracellular free calciumCarl Johnson; Fiscal Year: 2008..As a test case, these probes will be applied to the topic of biological clocks that have an important influence over mental and physical health. [unreadable] [unreadable] [unreadable]..
- MOLECULAR/GENETIC ANALYSIS OF BIOLOGICAL CLOCKSCarl Johnson; Fiscal Year: 2003..The long-term research goal is to understand the mechanism of this fascinating clockwork. ..
- BRET Interaction System for Circadian Clock ProteinsCarl Johnson; Fiscal Year: 2005..Our hypothesis is that clock protein interaction will not be simply a function of the protein abundance, but that there will be phase-specific interaction regulated by other factors than merely the proteins' abundance. ..
- Cell-permeant Clock ProteinsCarl Johnson; Fiscal Year: 2003..abstract_text> ..
- MOLECULAR/GENETIC ANALYSIS OF BIOLOGICAL CLOCKS IN CELLSCarl Johnson; Fiscal Year: 2005..Downstream events in the transduction of entraining signals will be studied in mammalian cells (CREB/CBP, cADPR) and model systems (cADPR, ZGT gene) to characterize the phase-resetting pathway. ..
- Regulation of West Nile virus gene expressionTheo Dreher; Fiscal Year: 2004..Our studies will also be applicable to other flaviviruses for which there is at present no vaccine, including dengue virus. ..
- Upstream ORFs: A general strategy for virus attenuationTheo Dreher; Fiscal Year: 2006..abstract_text> ..
- Structure Prediction of Helical Transmembrane ProteinsYing Xu; Fiscal Year: 2010..The predicted structural information for these proteins could provide a basis for understanding and controlling this disease. ..
- Microbial Correlates of Bacterial Vaginosis Treatment Failure and Recurrence in HMichael Ferris; Fiscal Year: 2008..Significance: The results should lead to more effective methods of diagnosing and treating BV, and preventing the serious sequelae associated with this common syndrome. ..