babesia

Summary

Summary: A genus of tick-borne protozoan parasites that infests the red blood cells of mammals, including humans. There are many recognized species, and the distribution is world-wide.

Top Publications

  1. ncbi Redescription of Babesia capreoli (Enigk and Friedhoff, 1962) from roe deer (Capreolus capreolus): isolation, cultivation, host specificity, molecular characterisation and differentiation from Babesia divergens
    Laurence Malandrin
    INRA, UMR1300 Bio agression, Epidémiologie et Analyse de Risque, F 44307 Nantes, France
    Int J Parasitol 40:277-84. 2010
  2. ncbi Divergence of the mitochondrial genome structure in the apicomplexan parasites, Babesia and Theileria
    Kenji Hikosaka
    Laboratory of Malariology, International Research Center of Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
    Mol Biol Evol 27:1107-16. 2010
  3. ncbi Babesiosis in dogs and cats--expanding parasitological and clinical spectra
    Laia Solano-Gallego
    Department of Pathology and Infectious Diseases, Royal Veterinary College of London, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK
    Vet Parasitol 181:48-60. 2011
  4. pmc Persistently infected horses are reservoirs for intrastadial tick-borne transmission of the apicomplexan parasite Babesia equi
    Massaro W Ueti
    Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 7040, USA
    Infect Immun 76:3525-9. 2008
  5. ncbi Questing ticks in suburban forest are infected by at least six tick-borne pathogens
    Caroline Reis
    USC INRA Bartonella Tiques, Anses, Maisons Alfort Cedex, France
    Vector Borne Zoonotic Dis 11:907-16. 2011
  6. ncbi Targeting the tick protective antigen subolesin reduces vector infestations and pathogen infection by Anaplasma marginale and Babesia bigemina
    Octavio Merino
    Instituto de Investigacion en Recursos Cinegeticos IREC CSIC UCLM JCCM, Ciudad Real, Spain
    Vaccine 29:8575-9. 2011
  7. pmc Prevalence and seasonality of tick-borne pathogens in questing Ixodes ricinus ticks from Luxembourg
    Anna L Reye
    Institute of Immunology, National Public Health Laboratory CRP Santé, Luxembourg, Luxembourg
    Appl Environ Microbiol 76:2923-31. 2010
  8. pmc Infection with a proposed new subspecies of Babesia canis, Babesia canis subsp. presentii, in domestic cats
    Gad Baneth
    School of Veterinary Medicine, Hebrew University, Rehovot 76100, Israel
    J Clin Microbiol 42:99-105. 2004
  9. pmc Transmission studies of Babesia microti in Ixodes ricinus ticks and gerbils
    Jeremy Gray
    Department of Environmental Resource Management, Faculty of Agriculture, Belfield, Dublin 4, Ireland
    J Clin Microbiol 40:1259-63. 2002
  10. pmc Babesia spp. and Anaplasma phagocytophilum in questing ticks, ticks parasitizing rodents and the parasitized rodents--analyzing the host-pathogen-vector interface in a metropolitan area
    Cornelia Silaghi
    Comparative Tropical Medicine and Parasitology, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Parasit Vectors 5:191. 2012

Detail Information

Publications259 found, 100 shown here

  1. ncbi Redescription of Babesia capreoli (Enigk and Friedhoff, 1962) from roe deer (Capreolus capreolus): isolation, cultivation, host specificity, molecular characterisation and differentiation from Babesia divergens
    Laurence Malandrin
    INRA, UMR1300 Bio agression, Epidémiologie et Analyse de Risque, F 44307 Nantes, France
    Int J Parasitol 40:277-84. 2010
    The recent use of the sole molecular identification of Babesia infecting European cervids has led to confusion between the closely related Babesia divergens and Babesia capreoli, and to their grouping together as "B. divergens-like"...
  2. ncbi Divergence of the mitochondrial genome structure in the apicomplexan parasites, Babesia and Theileria
    Kenji Hikosaka
    Laboratory of Malariology, International Research Center of Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
    Mol Biol Evol 27:1107-16. 2010
    ..The closely related genera Babesia and Theileria also have small mt genomes (6...
  3. ncbi Babesiosis in dogs and cats--expanding parasitological and clinical spectra
    Laia Solano-Gallego
    Department of Pathology and Infectious Diseases, Royal Veterinary College of London, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK
    Vet Parasitol 181:48-60. 2011
    Canine babesiosis caused by different Babesia species is a protozoal tick-borne disease with worldwide distribution and global significance...
  4. pmc Persistently infected horses are reservoirs for intrastadial tick-borne transmission of the apicomplexan parasite Babesia equi
    Massaro W Ueti
    Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 7040, USA
    Infect Immun 76:3525-9. 2008
    ..study, we established that adult male Rhipicephalus microplus ticks efficiently acquire the protozoal pathogen Babesia equi during acute and persistent infections and transmit it intrastadially to naïve horses...
  5. ncbi Questing ticks in suburban forest are infected by at least six tick-borne pathogens
    Caroline Reis
    USC INRA Bartonella Tiques, Anses, Maisons Alfort Cedex, France
    Vector Borne Zoonotic Dis 11:907-16. 2011
    ..6%), Babesia sp. EU1 (~1%), Bartonella birtlesii (0.1%), and Francisella tularensis (!1%)...
  6. ncbi Targeting the tick protective antigen subolesin reduces vector infestations and pathogen infection by Anaplasma marginale and Babesia bigemina
    Octavio Merino
    Instituto de Investigacion en Recursos Cinegeticos IREC CSIC UCLM JCCM, Ciudad Real, Spain
    Vaccine 29:8575-9. 2011
    ..In this study, we used the fact that these animals were naturally infected with Anaplasma marginale and Babesia bigemina to evaluate the effect of subolesin vaccination and gene knockdown on tick infection by these cattle ..
  7. pmc Prevalence and seasonality of tick-borne pathogens in questing Ixodes ricinus ticks from Luxembourg
    Anna L Reye
    Institute of Immunology, National Public Health Laboratory CRP Santé, Luxembourg, Luxembourg
    Appl Environ Microbiol 76:2923-31. 2010
    ..Mean infection rates of ticks were 11.3% for Borrelia burgdorferi sensu lato, 5.1% for Rickettsia sp., 2.7% for Babesia sp., and 1.9% for Anaplasma phagocytophilum. No tick was found to be infected with Coxiella sp...
  8. pmc Infection with a proposed new subspecies of Babesia canis, Babesia canis subsp. presentii, in domestic cats
    Gad Baneth
    School of Veterinary Medicine, Hebrew University, Rehovot 76100, Israel
    J Clin Microbiol 42:99-105. 2004
    Parasitemia with a large Babesia species was identified in two domestic cats from Israel...
  9. pmc Transmission studies of Babesia microti in Ixodes ricinus ticks and gerbils
    Jeremy Gray
    Department of Environmental Resource Management, Faculty of Agriculture, Belfield, Dublin 4, Ireland
    J Clin Microbiol 40:1259-63. 2002
    In order to investigate the possible role of Ixodes ricinus as a vector of zoonotic Babesia microti infection in Europe, a European rodent isolate (HK) and a zoonotic American isolate (GI) were studied in transmission experiments...
  10. pmc Babesia spp. and Anaplasma phagocytophilum in questing ticks, ticks parasitizing rodents and the parasitized rodents--analyzing the host-pathogen-vector interface in a metropolitan area
    Cornelia Silaghi
    Comparative Tropical Medicine and Parasitology, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Parasit Vectors 5:191. 2012
    The aims of this study were to evaluate the host-tick-pathogen interface of Babesia spp...
  11. ncbi Sequence heterogeneity in the 18S rRNA gene within Theileria equi and Babesia caballi from horses in South Africa
    Raksha Bhoora
    Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa
    Vet Parasitol 159:112-20. 2009
    ..A total of 488 samples were tested for the presence of Theileria equi and/or Babesia caballi using the reverse line blot hybridization assay...
  12. pmc Babesia divergens apical membrane antigen 1 and its interaction with the human red blood cell
    Estrella Montero
    Department of Blood Borne Parasites, Lindsley F Kimball Research Institute, New York Blood Center, 310 E 67th St, New York, NY 10021, USA
    Infect Immun 77:4783-93. 2009
    Multiple parasite ligand-erythrocyte receptor interactions must occur for successful Babesia and Plasmodium invasion of the human red cell...
  13. pmc Small risk of developing symptomatic tick-borne diseases following a tick bite in The Netherlands
    Ellen Tijsse-Klasen
    Laboratory for Zoonoses and Environmental Microbiology, Centre for Infectious Disease Control Netherlands, National Institute for Public Health and Environment RIVM, Bilthoven, The Netherlands
    Parasit Vectors 4:17. 2011
    ..Besides its causative agent, Borrelia burgdorferi s.l., other potential pathogens like Rickettsia, Babesia and Ehrlichia species are present in Ixodes ricinus ticks...
  14. pmc Extrachromosomal DNA in the Apicomplexa
    R J Wilson
    National Institute for Medical Research, London, United Kingdom
    Microbiol Mol Biol Rev 61:1-16. 1997
    ..The malarial mtDNA has a phage-like replication mechanism and undergoes extensive recombination like the mtDNA of some other lower eukaryotes...
  15. ncbi A study of the presence of B. burgdorferi, Anaplasma (previously Ehrlichia) phagocytophilum, Rickettsia, and Babesia in Ixodes ricinus collected within the territory of Belluno, Italy
    G Piccolin
    Observatory for the Study, Surveillance and Prevention of Tick Borne Diseases, ULSS, Veneto, Belluno, Italy
    Vector Borne Zoonotic Dis 6:24-31. 2006
    ..4% were positive for Ehrlichia, 1.6% were positive for Rickettsia, and 1.6% were positive for Babesia. The co-presence of Borrelia and Ehrlichia (1.2%) and Babesia (0.5%), Borrelia, Ehrlichia and Rickettsia (0...
  16. ncbi Estimating seroprevalence and variation to four tick-borne infections and determination of associated risk factors in cattle under traditional mixed farming system in Mbeere District, Kenya
    J M Gachohi
    International Livestock Research Institute ILRI, Old Naivasha Rd, Kabete, P O Box 30709 00100, Nairobi, Kenya
    Prev Vet Med 95:208-23. 2010
    ..of cattle to tick-borne disease (TBD) parasites (Theileria parva, Theileria mutans, Anaplasma marginale and Babesia bigemina) was conducted on traditional smallholder mixed farms in Mbeere District in Kenya...
  17. ncbi Epidemiological analysis of tick-borne diseases in Zambia
    Martin Simuunza
    Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Bearsden Road, Glasgow G61 1QH, Scotland, UK
    Vet Parasitol 175:331-42. 2011
    ..of livestock in sub-Saharan Africa are East Coast fever (caused by Theileria parva), babesiosis (caused by Babesia bigemina and B...
  18. ncbi Prevalence and incidence of tick-borne diseases in smallholder farming systems in the western-Kenya highlands
    O S Okuthe
    National Veterinary Research Centre, Kenya Agricultural Research Institute NVRC KARI, PO Box 32, Kikuyu, Kenya
    Vet Parasitol 141:307-12. 2006
    ..05). The difference in disease frequencies in two areas in close proximity shows the importance of monitoring disease events in order to understand and advice farmers in different production and farming systems appropriately...
  19. ncbi Evaluation of the in vitro growth-inhibitory effect of epoxomicin on Babesia parasites
    Mahmoud Aboulaila
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Vet Parasitol 167:19-27. 2010
    ..In the present study, the inhibitory effects of epoxomicin on the in vitro growth of bovine and equine Babesia parasites were evaluated...
  20. pmc Antiparasitic agent atovaquone
    Aaron L Baggish
    University of Connecticut School of Medicine, Farmington, Connecticut, USA
    Antimicrob Agents Chemother 46:1163-73. 2002
  21. pmc Feline vector-borne pathogens in the north and centre of Portugal
    Hugo Vilhena
    Department of Veterinary Medicine, Escola Universitária Vasco da Gama, Coimbra, Portugal
    Parasit Vectors 6:99. 2013
    ..In recent years, several clinical cases and epidemiological studies of feline vector-borne diseases (FVBD) have been reported worldwide. Nonetheless, information on FVBD agents and their prevalence in Portugal is scarce...
  22. ncbi Development and evaluation of real-time PCR assays for the quantitative detection of Babesia caballi and Theileria equi infections in horses from South Africa
    Raksha Bhoora
    Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, South Africa
    Vet Parasitol 168:201-11. 2010
    ..chain reaction (qPCR) assay using a TaqMan minor groove binder (MGB) probe was developed for the detection of Babesia caballi infection in equids from South Africa...
  23. ncbi Identification, genetic diversity and prevalence of Theileria and Babesia species in a sheep population from Northern Spain
    Daniel Nagore
    Department of Animal Health, Instituto Vasco de Investigación y Desarrollo Agrario Berreaga 1, 48160 Derio, Bizkaia, Spain
    Int J Parasitol 34:1059-67. 2004
    The genetic diversity and prevalence of virtually all Theileria and Babesia species in a sheep population were studied using a specifically designed reverse line blot macroarray...
  24. ncbi Dermacentor variabilis and boophilus microplus (Acari: Ixodidae): experimental vectors of Babesia equi to equids
    David Stiller
    J Med Entomol 39:667-70. 2002
    ..Boophilus microplus (Canestrini), D. andersoni Stiles, D. occidentalis Marx, and D. variabilis (Say)] for Babesia equi (Laveran 1901) was evaluated by delayed transfer of male ticks from infected to susceptible equids or by ..
  25. pmc Coexistence of pathogens in host-seeking and feeding ticks within a single natural habitat in Central Germany
    Jan Franke
    Department of Food and Environmental Hygiene, Institute of Nutrition, Friedrich Schiller University Jena, Dornburger Str 29, 07743 Jena, Germany
    Appl Environ Microbiol 76:6829-36. 2010
    ..15.2%) and A. phagocytophilum (3.2%) than rodent-feeding ticks (2.6%; 1.1%) or questing ticks (5.1%; 0%). Babesia spp. showed higher prevalence rates in ticks parasitizing birds (13.2%) and host-seeking ticks (10...
  26. pmc Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways
    Stefan Baumeister
    Parasitologie, Fachbereich Biologie, Philipps Universitat, Marburg, Germany
    PLoS ONE 6:e19334. 2011
    ..Surprisingly, the compounds are inactive against a range of apicomplexans replicating in nucleated cells, including Toxoplasma gondii...
  27. ncbi Development of TaqMan-based real-time PCR assays for diagnostic detection of Babesia bovis and Babesia bigemina
    Chulmin Kim
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    Am J Trop Med Hyg 77:837-41. 2007
    Two TaqMan-based real-time polymerase chain reaction (PCR) assays devised for the detection of two bovine Babesia parasites, Babesia bovis and B...
  28. ncbi Phylogeny and evolution of the piroplasms
    M T Allsopp
    Onderstepoort Veterinary Institute, South Africa
    Parasitology 108:147-52. 1994
    Small subunit ribosomal RNA (srRNA) genes of three Theileria species, one Cytauxzoon and four Babesia species were amplified using the polymerase chain reaction (PCR), cloned and sequenced...
  29. pmc Growth-inhibitory effects of artesunate, pyrimethamine, and pamaquine against Babesia equi and Babesia caballi in in vitro cultures
    Akiko Nagai
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine Obihiro, Hokkaido 080 8555, Japan
    Antimicrob Agents Chemother 47:800-3. 2003
    ..drugs, artesunate, pyrimethamine, and pamaquine, were evaluated for their growth-inhibitory effects against Babesia equi and Babesia caballi in in vitro culture. B. equi was more resistant to pyrimethamine than B. caballi. B...
  30. ncbi Foci report on indigenous Dermacentor reticulatus populations in Belgium and a preliminary study of associated babesiosis pathogens
    C Cochez
    Research Laboratory for Vector Borne Diseases, Queen Astrid Military Hospital, Brussels, Belgium
    Med Vet Entomol 26:355-8. 2012
    ..Ticks were found mainly from early March until the end of May and a peak in activity was apparent in March. A Babesia spp...
  31. ncbi Prevalence of Babesia canis, Borrelia afzelii, and Anaplasma phagocytophilum infection in hard ticks removed from dogs in Warsaw (central Poland)
    Wojciech Zygner
    Division of Parasitology and Parasitic Diseases, Department of Preclinical Sciences, Faculty of Veterinary Medicine, Warsaw Agricultural University, Ciszewskiego 8, 02 786 Warsaw, Poland
    Vet Parasitol 153:139-42. 2008
    The purposes of this study were to specify the occurrence and prevalence of Babesia canis, Borrelia burgdorferi sensu lato, and Anaplasma phagocytophilum in ticks removed from dogs in Warsaw, and to determine the Borrelia species ..
  32. ncbi Development of a loop-mediated isothermal amplification (LAMP) assay for rapid diagnosis of Babesia canis infections
    H Muller
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Borstel, Germany
    Transbound Emerg Dis 57:63-5. 2010
    ..b>Babesia canis belongs to the Piroplasmidae and there are three described subspecies, namely B. canis canis, B...
  33. ncbi The potential role of migratory birds in transmission cycles of Babesia spp., Anaplasma phagocytophilum, and Rickettsia spp
    Anke Hildebrandt
    Institute of Medical Microbiology, Medical University Laboratories, Friedrich Schiller University, Erlanger Allee 101, D 07747 Jena, Thuringia, Germany
    Ticks Tick Borne Dis 1:105-7. 2010
    b>Babesia spp., Anaplasma phagocytophilum, and Rickettsia spp. are potentially emerging tick-borne pathogens, whereas many issues about their ecology, e.g. reservoir host specificity, are still unclear...
  34. ncbi Longitudinal field study on bovine Babesia spp. and Anaplasma phagocytophilum infections during a grazing season in Belgium
    Laetitia Lempereur
    Laboratory of Parasitology and Parasitic Diseases, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, University of Liege, 4000 Liege, Belgium
    Parasitol Res 110:1525-30. 2012
    ..Seroprevalences to Babesia spp. were measured as 10.7%, 20%, and 12...
  35. ncbi Emerging perspectives in the research of bovine babesiosis and anaplasmosis
    Carlos E Suarez
    Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, WA 99164 6630, USA
    Vet Parasitol 180:109-25. 2011
    The Babesia bovis and B...
  36. ncbi The prevention of transmission of Babesia canis canis by Dermacentor reticulatus ticks to dogs using a novel combination of fipronil, amitraz and (S)-methoprene
    Frans Jongejan
    Utrecht Centre for Tick borne Diseases UCTD, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands
    Vet Parasitol 179:343-50. 2011
    ..All dogs were infested with adult Dermacentor reticulatus ticks harbouring Babesia canis canis. Babesia canis canis was transmitted by D...
  37. ncbi Growth inhibitory effect of triclosan on equine and bovine Babesia parasites
    Sabine Bork
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    Am J Trop Med Hyg 68:334-40. 2003
    ..recently been reported to inhibit the growth of Plasmodium species and Toxoplasma gondii, on bovine and equine Babesia parasites in in vitro cultures The growth of Babesia bovis and B...
  38. pmc Expression of equi merozoite antigen 2 during development of Babesia equi in the midgut and salivary gland of the vector tick Boophilus microplus
    Massaro W Ueti
    Program in Vector Borne Diseases, Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington 99164 7040, USA
    J Clin Microbiol 41:5803-9. 2003
    Equi merozoite antigens 1 and 2 (EMA-1 and EMA-2) are Babesia equi proteins expressed on the parasite surface during infection in horses and are orthologues of proteins in Theileria spp...
  39. ncbi Artesunate, a potential drug for treatment of Babesia infection
    Youn Kyoung Goo
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    Parasitol Int 59:481-6. 2010
    The effects of artesunate, a water-soluble artemisinin derivative, against Babesia species, including Babesia bovis, Babesia gibsoni and Babesia microti were studied. Cultures of B. bovis and B. gibsoni were treated with 0.26, 2...
  40. ncbi Organization, transcription, and expression of rhoptry associated protein genes in the Babesia bigemina rap-1 locus
    Carlos E Suarez
    Program in Vector Borne Diseases, Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 7040, USA
    Mol Biochem Parasitol 127:101-12. 2003
    The Babesia bigemina rap-1 gene locus contains five tandemly arranged copies of rap-1a genes. However, the size of the locus, as defined by conserved, unrelated orfs at the 5' and 3' ends, suggests that additional genes may be present...
  41. ncbi Detection of bovine babesiosis in Mozambique by a novel seminested hot-start PCR method
    Tiago M Martins
    UTPAM, INETI, Est Paço do Lumiar 1649 038 Lisboa, Portugal
    Vet Parasitol 153:225-30. 2008
    Babesiosis is a tick borne disease (TBD) caused by parasites of the genus Babesia, with considerable worldwide economic, medical, and veterinary impact...
  42. ncbi Repeated high dose imidocarb dipropionate treatment did not eliminate Babesia caballi from naturally infected horses as determined by PCR-reverse line blot hybridization
    C M Butler
    Department of Equine Sciences, Medicine Section, Utrecht University, PO Box 80 153, 3508 TD Utrecht, The Netherlands
    Vet Parasitol 151:320-2. 2008
    Imidocarb treatment of horses infected with Babesia caballi is supposed to eliminate the infection, but data on the efficacy of this treatment is scarce...
  43. ncbi Coexistence DNA of Borrelia burgdorferi sensu lato and Babesia microti in Ixodes ricinus ticks from north-western Poland
    Bogumiła Skotarczak
    Faculty of Biology, Department of Genetics, University of Szczecin, Piastow 40B, 71 065 Szczecin, Poland
    Ann Agric Environ Med 9:25-8. 2002
    ..borreliosis), caused by the spirochaete Borrelia burgdorferi sensu lato and babesiosis, induced by the protozoan Babesia microti...
  44. pmc Imidocarb dipropionate clears persistent Babesia caballi infection with elimination of transmission potential
    O Nicolas Schwint
    Program in Vector Borne Diseases, Department of Veterinary Microbiology and Pathology, School for Global Animal Heath, Washington State University, Pullman, WA 99164 7040, USA
    Antimicrob Agents Chemother 53:4327-32. 2009
    ..The limited repertoire of antimicrobial agents targeted at protozoal parasites magnifies this challenge. Using Babesia caballi as both a model and a specific apicomplexan pathogen for which evidence of the elimination of ..
  45. ncbi Comparative evaluation of a point-of-care immunochromatographic test SNAP 4Dx with molecular detection tests for vector-borne canine pathogens in Hong Kong
    Samson S Y Wong
    State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Hong Kong
    Vector Borne Zoonotic Dis 11:1269-77. 2011
    ..The presence of Wolbachia DNAemia (6%) correlated well with the molecular test and immunochromatographic antigen test for D. immitis...
  46. ncbi Pathogens of emerging tick-borne diseases, Anaplasma phagocytophilum, Rickettsia spp., and Babesia spp., in ixodes ticks collected from rodents at four sites in Switzerland (Canton of Bern)
    Caroline Burri
    Laboratory of Eco Epidemiology of Parasites, Institute of Biology, University of Neuchatel, Neuchatel, Switzerland
    Vector Borne Zoonotic Dis 11:939-44. 2011
    ..and Babesia spp., in field-derived ticks that detached from 79 small mammals...
  47. pmc Babesia species occurring in Austrian Ixodes ricinus ticks
    Marion Blaschitz
    Division of Infection and Immunology, Medical University of Vienna, Kinderspitalgasse 15, 1095 Vienna, Austria
    Appl Environ Microbiol 74:4841-6. 2008
    ..and 11 Haemaphysalis concinna ticks, from sampling sites throughout Austria were examined for the presence of Babesia spp. by using 18S rRNA gene PCR and sequencing, and the overall mean infection rate was 51.04%...
  48. ncbi Wild ungulates as Babesia hosts in northern and central Italy
    Maria Paola Tampieri
    Department of Veterinary Public Health and Animal Pathology, Alma Mater Studiorum University of Bologna, Italy
    Vector Borne Zoonotic Dis 8:667-74. 2008
    b>Babesia and Theileria species were investigated in wild ungulates of Northern and Central Italy. Of 355 blood samples examined, 108 (30...
  49. ncbi Babesia and plasmodia increase host erythrocyte permeability through distinct mechanisms
    Abdulnaser Alkhalil
    The Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda MD 20892, USA
    Cell Microbiol 9:851-60. 2007
    ..Here, we examined this question using human erythrocytes infected with Babesia divergens, a distantly related apicomplexan parasite that can cause severe disease in immunocompromised humans...
  50. ncbi PCR detection of granulocytic Anaplasma and Babesia in Ixodes ricinus ticks and birds in west-central Poland
    Bogumiła Skotarczak
    Departament of Genetics, Faculty of Biology, Szczecin University, al Piastow 40b, 71 065 Szczecin, Poland
    Ann Agric Environ Med 13:21-3. 2006
    The aim of the study was to establish the role of forest birds as reservoirs of Anaplasma phagocytophilum and Babesia spp. in Wielkopolski National Park. A total of 108 birds from 9 species were collected between May-September 2002...
  51. ncbi Loop-mediated isothermal amplification (LAMP) detection of Babesia orientalis in water buffalo (Bubalus babalis, Linnaeus, 1758) in China
    Lan He
    State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Hubei, Wuhan, China
    Vet Parasitol 165:36-40. 2009
    ..In this study, a LAMP method was developed for specific detection of Babesia orientalis in water buffalo (Bubalus babalis, Linnaeus, 1758)...
  52. pmc Seroprevalence of Babesia infections in humans exposed to ticks in midwestern Germany
    Klaus Peter Hunfeld
    Institute of Medical Microbiology, University Hospital of Frankfurt, D 60596 Frankfurt Main, Germany
    J Clin Microbiol 40:2431-6. 2002
    ..The aim of this study was to investigate the prevalence of Babesia infections in a human population in Germany...
  53. ncbi Detection of Babesia bigemina infection in strains of Rhipicephalus (Boophilus) microplus collected from outbreaks in south Texas
    F D Guerrero
    USDA ARS Knipling Bushland, US Livestock Insects Research Laboratory, Kerrville, TX 78028, USA
    Vet Parasitol 145:156-63. 2007
    ..Microscopic evidence for Babesia bigemina infection was found in blood smears from the affected animals and a PCR assay was designed to detect the ..
  54. ncbi Detection of Anaplasma platys and Babesia canis vogeli and their impact on platelet numbers in free-roaming dogs associated with remote Aboriginal communities in Australia
    G K Brown
    Discipline of Biological Sciences, School of Environmental and Life Sciences, University of Newcastle, Callaghan NSW 2308, Australia
    Aust Vet J 84:321-5. 2006
    To detect Anaplasma platys and Babesia canis vogeli infection, using polymerase chain reaction (PCR)-based assays, in free-roaming dogs associated with eight Aboriginal communities in remote areas of Australia and to determine the impact ..
  55. ncbi First case of babesiosis caused by Babesia canis canis in a dog from Norway
    Øivind Øines
    Section for Parasitology, National Veterinary Institute, Ullevaalsveien 68, PB 750 Sentrum, N 0106 Oslo, Norway
    Vet Parasitol 171:350-3. 2010
    ..examination of thin blood film revealed large, basophilic, bodies inside erythrocytes, indicative of a large Babesia sp. Molecular analysis using PCR, indicated the presence of a Babesia spp. in the blood...
  56. ncbi An overview of the Babesia, Plasmodium and Theileria genomes: a comparative perspective
    Audrey O T Lau
    Program in Genomics, Department of Veterinary Microbiology and Pathology, School for Global Animal Health, College of Veterinary Medicine, Washington State University, Pullman, WA 99164 7040, USA
    Mol Biochem Parasitol 164:1-8. 2009
    b>Babesia, Plasmodium and Theileria form a triad of apicomplexan hemoparasites and are accountable for significant mortality and morbidity to humans and animals globally...
  57. pmc Occurrence of Babesia spp., Rickettsia spp. and Bartonella spp. in Ixodes ricinus in Bavarian public parks, Germany
    Sabine Schorn
    Comparative Tropical Medicine and Parasitology, Ludwig Maximilians University, Munich, Germany
    Parasit Vectors 4:135. 2011
    ..collected in public parks of different Bavarian cities in a 2-year survey (2009 and 2010) and screened for DNA of Babesia spp., Rickettsia spp. and Bartonella spp. by PCR...
  58. ncbi Detection of Babesia EU1 in Ixodes ricinus ticks in northern Italy
    Rudi Cassini
    Dipartimento di Scienze Sperimentali Veterinarie, Universita degli Studi di Padova, Viale dell Universita, 16, 35020 Legnaro PD, Italy
    Vet Parasitol 171:151-4. 2010
    b>Babesia EU1, a potentially important emerging zoonotic pathogen, already detected in ticks and wild ruminants of different European Countries, was found in three pools of Ixodes ricinus nymphs in three different sites located in a single ..
  59. ncbi Prevalence of five pathogenic agents in questing Ixodes ricinus ticks from western France
    Violaine Cotte
    UMR 956 INRA AFSSA ENVA UPVM, AFSSA, Maisons Alfort, France
    Vector Borne Zoonotic Dis 10:723-30. 2010
    ..b>Babesia sp., and very likely Bartonella sp...
  60. ncbi Coexistence of Borrelia spp. and Babesia spp. in Ixodes ricinus ticks in Middle Germany
    Anke Hildebrandt
    Institute of Medical Microbiology, Friedrich Schiller University, Jena, Germany
    Vector Borne Zoonotic Dis 10:831-7. 2010
    ..ospA gene) and Babesia spp. (18S rRNA gene). Overall, 27.0% (270/1000) were infected with Borrelia species...
  61. ncbi First evidence of Babesia gibsoni (Asian genotype) in dogs in Western Europe
    K Hartelt
    Baden Württemberg State Health Office, District Government Stuttgart, Germany
    Vector Borne Zoonotic Dis 7:163-6. 2007
    Canine babesiosis in Europe is generally caused by Babesia canis canis and Babesia canis rossi. Here we describe the first two autochthonous cases of Babesia gibsoni (Asian genotype) infection in Germany...
  62. ncbi Infection of dogs in north-west Spain with a Babesia microti-like agent
    A T Camacho
    Laboratorio Lema and Bandin, Vigo, Spain
    Vet Rec 149:552-5. 2001
    ..None of them had previously been in areas endemic for Babesia gibsoni, which was until recently the only small piroplasm known to parasitise dogs...
  63. ncbi Molecular characterization of a Babesia gibsoni isolate from a Spanish dog
    A Criado-Fornelio
    Laboratory of Parasitology, Microbiology and Parasitology Department, Faculty of Pharmacy, University of Alcala de Henares, 28871, Alcala de Henares, Spain
    Vet Parasitol 117:123-9. 2003
    b>Babesia gibsoni is a morphologically small Babesia species that infects dogs. Molecular techniques have shown that some small Babesia sp. recently described in canids are not related to the original B...
  64. ncbi Epidemiological aspects on vector-borne infections in stray and pet dogs from Romania and Hungary with focus on Babesia spp
    Dietmar Hamel
    Comparative Tropical Medicine and Parasitology, Veterinary Faculty, Ludwig Maximilians Universitat, Leopoldstraße 5, 80802 Munich, Germany
    Parasitol Res 110:1537-45. 2012
    ..Eleven different parasitic and bacterial vector-borne pathogens-Babesia canis canis, Babesia canis vogeli, Babesia gibsoni, Babesia felis-like, Hepatozoon canis, Leishmania spp...
  65. ncbi Detection and molecular characterization of Babesia caballi and Theileria equi isolates from endemic areas of Brazil
    Alexandra Heim
    Institute for Comparative Tropical Medicine and Parasitology, Ludwig Maximilian University Munich, Leopoldstr 5, 80802, Munich, Germany
    Parasitol Res 102:63-8. 2007
    ..The plasma was examined by the indirect fluorescent antibody test for detection of antibodies against Babesia caballi and Theileria equi...
  66. ncbi Babesia canis and Babesia rossi co-infection in an untraveled Nigerian dog
    Joshua Kamani
    Parasitology Division, National Veterinary Research, Institute PMB 01, Vom, Plateau State, Nigeria
    Vet Parasitol 173:334-5. 2010
    ..range of sizes (1-5 μm in length) in red blood cells, raising a suspicion of a co-infection with two or more Babesia species. Specific PCR assays for canine Babesia spp...
  67. ncbi Identification of three CCp genes in Babesia divergens: novel markers for sexual stages parasites
    C A M Becker
    UMR INRA ONIRIS 1300 BioEpAR, ITPH Group, Nantes, France
    Mol Biochem Parasitol 174:36-43. 2010
    b>Babesia divergens, a tick-borne protozoan parasite of red blood cells, is the main agent of bovine and human babesiosis in Europe...
  68. ncbi First evidence and molecular characterization of Babesia vogeli in naturally infected dogs and Rhipicephalus sanguineus ticks in southern France
    M René
    Universite de Lyon, VetAgro Sup, Jeune Equipe Hémopathogènes Vectorisés, F 69280 Marcy l Etoile, France
    Vet Parasitol 187:399-407. 2012
    ..is an emerging tick-borne disease of animals and humans caused by intraerythrocytic protozoa of the genera Babesia and Theileria...
  69. pmc Multiple co-infections of rodents with hantaviruses, Leptospira, and Babesia in Croatia
    Ante Tadin
    University Hospital for Infectious Diseases Dr Fran Mihaljevic, Research Department, Zagreb, Croatia
    Vector Borne Zoonotic Dis 12:388-92. 2012
    Hantaviruses, Leptospira spp., and Babesia spp. are rodent-borne pathogens present worldwide. We studied multiple co-infections of small rodents in Croatia with all three pathogens...
  70. ncbi Multiplex real-time qPCR for the detection of Ehrlichia canis and Babesia canis vogeli
    Ofer Peleg
    Genaphora Ltd, 4 Habarzel St, Tel Aviv 69710, Israel
    Vet Parasitol 173:292-9. 2010
    Ehrlichia canis and Babesia canis vogeli are two tick-borne canine pathogens with a worldwide importance. Both pathogens are transmitted by Rhipicephalus sanguineus, the brown dog tick, which has an increasing global distribution...
  71. ncbi Systemic inflammatory responses in dogs experimentally infected with Babesia canis; a haematological study
    Th P M Schetters
    Department of Parasitology, Intervet Schering Plough Animal Health, P O Box 31, 5830 AA Boxmeer, The Netherlands
    Vet Parasitol 162:7-15. 2009
    A detailed haematological study of dogs that were infected with low, moderate or high numbers of Babesia canis-infected red blood cells was performed in an attempt to elucidate the pathogenesis early after B. canis infection...
  72. pmc Molecular basis for variable expression of merozoite surface antigen gp45 among American isolates of Babesia bigemina
    T G Fisher
    Program in Vector Borne Diseases, Department of Veterinary Microbiology and Pathology, Washington State University, Pullman 99164 7040, USA
    Infect Immun 69:3782-90. 2001
    ..Immunization with the merozoite surface glycoprotein gp45 induces protection against challenge using the homologous Babesia bigemina strain. However, gp45 B-cell epitopes are highly polymorphic among B...
  73. ncbi Development of a practical immunochromatographic test with recombinant P50 for the diagnosis of Babesia gibsoni infection in dogs
    R A Verdida
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Parasitology 131:769-74. 2005
    An immunochromatographic test (ICT), using recombinant truncated P50 (P50t), for the detection of antibodies to Babesia gibsoni was developed and evaluated...
  74. ncbi Serological survey of Babesia bovis and Babesia bigemina in cattle in South Africa
    Mohamad Alaa Terkawi
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Vet Parasitol 182:337-42. 2011
    ..ELISA) and the standard indirect fluorescent antibody test (IFAT) to determine the serological prevalence of Babesia bovis and Babesia bigemina. The results showed that 35.3% and 39.7% of cattle were positive for B...
  75. ncbi Detection of Babesia gibsoni and the canine small Babesia 'Spanish isolate' in blood samples obtained from dogs confiscated from dogfighting operations
    Todd J Yeagley
    Department of Veterinary Pathobiology, Center for Veterinary Health Science, Oklahoma State University, Stillwater, OK 74078, USA
    J Am Vet Med Assoc 235:535-9. 2009
    To determine the prevalence of Babesia gibsoni infection in dogs that were confiscated from dogfighting operations.
  76. ncbi Molecular characterization of Babesia kiwiensis from the brown kiwi (Apteryx mantelli)
    R Jefferies
    School of Veterinary and Biomedical Sciences, Murdoch University, Murdoch, 6150 Western Australia, Australia
    J Parasitol 94:557-60. 2008
    To further investigate the recently described avian piroplasm, Babesia kiwiensis, blood samples were collected from 13 wild-caught and 8 zoo-captive brown kiwi (Apteryx mantelli) and screened for the presence of piroplasm DNA using a ..
  77. ncbi Molecular prevalence of Bartonella, Babesia, and hemotropic Mycoplasma sp. in dogs with splenic disease
    M Varanat
    Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA
    J Vet Intern Med 25:1284-91. 2011
    ..The spleen plays an important role in the immunologic control or elimination of vector-transmitted, blood-borne pathogens, including Bartonella sp., Babesia sp., and hemotropic Mycoplasma sp.
  78. ncbi Failure to demonstrate Babesia, Anaplasma or Ehrlichia in thrombocytopenic dogs from St Kitts
    Patrick J Kelly
    Ross University School of Veterinary Medicine, PO Box 334, Basseterre, St Kitts, West Indies
    J Infect Dev Ctries 3:561-3. 2009
    Thrombocytopenia is common in dogs on St Kitts but there is no data on the possible etiological role played by infections with Anaplasma, Babesia and Ehrlichia, other than E. canis, which are known to occur in the Caribbean.
  79. pmc Conformational dependence and conservation of an immunodominant epitope within the babesia equi erythrocyte-stage surface protein equi merozoite antigen 1
    Cristina W Cunha
    Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington 99164 7040, USA
    Clin Diagn Lab Immunol 9:1301-6. 2002
    Equi merozoite antigen 1 (EMA-1) is an immunodominant Babesia equi erythrocyte-stage surface protein. A competitive enzyme-linked immunosorbent assay (ELISA), based on inhibition of monoclonal antibody (MAb) 36/133...
  80. ncbi West-to-east differences of Babesia canis canis prevalence in Dermacentor reticulatus ticks in Slovakia
    Michaela Kubelová
    Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences, Palackeho 1 3, 612 42 Brno, Czech Republic
    Vet Parasitol 180:191-6. 2011
    b>Babesia canis canis is the most frequent causative agent of canine babesiosis in Central Europe, frequently causing severe disease. Recently, many new endemic foci of this disease have been reported from European countries...
  81. ncbi A fatal case of human babesiosis in Portugal: molecular and phylogenetic analysis
    S Centeno-Lima
    Centro de Malaria e Outras Doencas Tropicais, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Portugal
    Trop Med Int Health 8:760-4. 2003
    ..A high parasitaemia (30%) of Babesia parasites was found in Giemsa-stained blood smears and, despite treatment, the patient died several weeks later ..
  82. ncbi Genetic diversity of Babesia in Ixodes persulcatus and small mammals from North Ural and West Siberia, Russia
    V A Rar
    Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, pr Lavrent eva 8, Novosibirsk 630090, Russian Federation
    Parasitology 138:175-82. 2011
    The aim of this work was to study the prevalence and genetic diversity of Babesia in Ixodes persulcatus ticks and small mammals from Ural and Siberia in Russia.
  83. ncbi Evidence of an acute phase response in dogs naturally infected with Babesia canis
    Vesna Matijatko
    Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, 10000 Zagreb, Croatia
    Vet Parasitol 144:242-50. 2007
    ..number (PLT) were quantified and compared with the acute phase proteins (APPs) in dogs naturally infected with Babesia canis and healthy dogs...
  84. ncbi Expression of Babesia equi EMA-1 and EMA-2 during merozoite developmental stages in erythrocyte and their interaction with erythrocytic membrane skeleton
    Sanjay Kumar
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Mol Biochem Parasitol 133:221-7. 2004
    ..we investigated the cellular localizations and expression patterns of equi merozoite antigens (EMA) -1 and -2 of Babesia equi during its asexual erythrocytic-developmental cycle using anti-EMA-1t or -2t mono-specific mouse serum...
  85. ncbi Modification of host erythrocyte membranes by trypsin and chymotrypsin treatments and effects on the in vitro growth of bovine and equine Babesia parasites
    Masashi Okamura
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    J Parasitol 93:208-11. 2007
    ..we investigated the effects of protease pretreatments of host erythrocytes (RBC) on the in vitro growth of bovine Babesia parasites (Babesia bovis and B. bigemina) and equine Babesia parasites (B. equi and B. caballi)...
  86. ncbi 'Babesia gibsoni' of dogs from North America and Asia belong to different species
    M Zahler
    Institute for Comparative Tropical Medicine and Parasitology, University of Munich, Germany
    Parasitology 120:365-9. 2000
    18S rDNA sequences from 4 isolates of Babesia gibsoni originating from Japan, Malaysia and Sri Lanka were compared with a previously published, 0.5 kb portion of the 18S rDNA from a B...
  87. ncbi Molecular identification of Babesia parasites isolated from Ixodes ricinus ticks collected in northwestern Poland
    Norman Pieniazek
    Department of Genetics, Szczecin University, al Piastow 40b, 71 065 Szczecin, Poland
    J Parasitol 92:32-5. 2006
    In the present study, PCR has been applied to detect and analyze DNA of Babesia spp. extracted from Ixodes ricinus ticks. Collection of I...
  88. ncbi Seroprevalence of Babesia ovis in mouflon sheep in Spain
    D Ferrer
    Unitat de Parasitologia i Malalties Parasitàries, Facultat de Veterinaria, Universitat Autonoma de Barcelona, Spain
    J Wildl Dis 34:637-9. 1998
    A serological survey detected antibodies against Babesia ovis in mouflon sheep (Ovis musimon) from two different reserves located in Catalonia in northeastern Spain. An indirect fluorescent antibody test (IFAT) was developed using a B...
  89. ncbi Different Babesia canis isolates, different diseases
    T P Schetters
    Department of Parasitology, Intervet International BV, Boxmeer, The Netherlands
    Parasitology 115:485-93. 1997
    ..surface immunofluorescence isolate-specific antigens were detected on the membrane of erythrocytes infected with Babesia parasites. In addition, the strains reacted differently with Plasmagel in that the European isolate (B.c...
  90. ncbi [Human babesiosis]
    P Meliani
    Service des Maladies Infectieuses et Tropicales, Hopital Purpan, Place du Docteur Baylac, 31059 Toulouse, France
    Med Mal Infect 36:499-504. 2006
    b>Babesia is one of the most ubiquitous and widespread blood parasite in the world based on numbers and distribution of species in animals. The clinical presentation may vary according to the incriminated species...
  91. ncbi Presumptive Babesia ovis infection in a spanish ibex (Capra pyrenaica)
    I Marco
    Servicio de Ecopatologia de Fauna Salvaje, School of Veterinary Medicine, Autonomous University of Barcelona, Bellaterra, Spain
    Vet Parasitol 87:217-21. 2000
    ..Piroplasms were observed within parasitized erythrocytes and presumptively identified as Babesia spp. Ticks were identified exclusively as Ripicephalus bursa...
  92. ncbi [Roe deer (Capreolus capreolus) and red deer (Cervus elaphus) as a reservoir of protozoans from Babesia and Theileria genus in north-western Poland]
    Marek Sawczuk
    Katedra Genetyki, Uniwersytet Szczeciński
    Wiad Parazytol 51:243-7. 2005
    The species of genus Babesia and Thelieria are obligate intracellular pathogens that multiply in both vertebrate and invertebrate hosts...
  93. ncbi Morphology and genetics of a Babesia isolate from Capreolus capreolus
    G Cancrini
    Dipartimento di Scienze di Sanità Pubblica, Sez Parassitologia, Universita La Sapienza, P le Aldo Moro, 2, 00185 Roma, Italy
    J Wildl Dis 44:168-71. 2008
    A Babesia isolate that was morphologically distinct from Babesia capreoli and very similar to B. divergens was found in the blood of a roe deer (Capreolus capreolus) found dead in central Italy...
  94. pmc Molecular diagnosis of Theileria and Babesia species infecting cattle in Northern Spain using reverse line blot macroarrays
    Josune García-Sanmartín
    Department of Animal Health, NEIKER Instituto Vasco de Investigación y Desarrollo Agrario, Berreaga 1, 48160 Derio, Bizkaia, Spain
    BMC Vet Res 2:16. 2006
    Piroplasmosis in cattle is caused by tick-borne haemoprotozoan parasites of the genera Theileria and Babesia. Molecular detection techniques offer higher sensitivity and specificity than microscopy examination methods and serological ..
  95. ncbi Canine babesiosis
    J P Schoeman
    Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110 South Africa
    Onderstepoort J Vet Res 76:59-66. 2009
    ..This paper deals with canine babesiosis with specific reference to pathogenesis, clinical findings, complications, diagnosis and treatment, as well as newly identified prognostic factors in Babesia rossi babesiosis.
  96. ncbi Detection of Babesia vogeli in stray cats of metropolitan Bangkok, Thailand
    Patcharathorn Simking
    Department of Parasitology, Faculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand
    Vet Parasitol 173:70-5. 2010
    ..The purpose of this study was to determine the prevalence and factors associated with the distribution of Babesia species infections among stray cats in Bangkok...
  97. ncbi Clinicopathological findings, molecular detection and characterization of Babesia gibsoni infection in a sick dog from Italy
    M Trotta
    Laboratorio d Analisi Veterinarie San Marco, Via Sorio, 114c, 35141 Padua, Italy
    Vet Parasitol 165:318-22. 2009
    ..in diameter), and round to oval to band-like piroplasms within many red blood cells consistent with small form Babesia spp. or Theileria spp...
  98. ncbi Isolation and amplification by polymerase chain reaction DNA of Babesia microti and Babesia divergens in ticks in Poland
    B Skotarczak
    Department of Genetics, Faculty of Biology, Szczecin University, Piastow 40 B, 71 065 Szczecin, Poland
    Ann Agric Environ Med 8:187-9. 2001
    b>Babesia microti and B. divergens, the etiological agents of human babesiosis, are transmitted by the bite of Ixodes ricinus...
  99. ncbi Babesia divergens experimental infection of spleen-intact sheep results in long-lasting parasitemia despite a strong humoral response: preliminary results
    Emmanuelle Moreau
    Ecole Nationale Veterinaire, UMR 1300 BioEpAR, ENVN, Atlanpole La Chantrerie, BP 40706, F 44307 Nantes Cedex 03, France
    Vet Parasitol 166:205-11. 2009
    b>Babesia divergens is an intraerythrocytic Apicomplexa and the main agent of bovine babesiosis in Europe...
  100. ncbi New localities of Dermacentor reticulatus tick (vector of Babesia canis canis) in central and eastern Poland
    W Zygner
    Division of Parasitology and Parasitic Diseases, Department of Preclinical Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences SGGW, Ciszewskiego 8, 02 786 Warsaw, Poland
    Pol J Vet Sci 12:549-55. 2009
    Dermacentor reticulatus tick is a vector and final host of Babesia canis canis, protozoan parasite of the dog. In Poland and other European countries, endemic regions for canine babesiosis caused by B...
  101. ncbi The first detection of Babesia EU1 and Babesia canis canis in Ixodes ricinus ticks (Acari, Ixodidae) collected in urban and rural areas in northern Poland
    Stella Cieniuch
    Department of Tropical Parasitology, Interfaculty Institute of Maritime and Tropical Medicine, Medical University of Gdansk, Gdynia, Poland
    Pol J Microbiol 58:231-6. 2009
    ..microorganisms as TBE viruses, Borrelia burgdoferi sensu lato, Anaplasma phagocytophilum, Rickettsia helvetica, Babesia divergens and B. microti in our country...

Research Grants62

  1. 7th International Congress on Toxoplasmosis
    Kami Kim; Fiscal Year: 2003
    ..The Apicomplexa include most of the major protozoan pathogens of humans and animals, such as Plasmodia (malaria), Babesia, Theileria, Cryptosporidia, Cyclospora, Neospora, Eimeria, and Isospora...
  2. CFI Pathogen Inactivation Technology
    Trevor P Castor; Fiscal Year: 2010
    ..In addition to viruses, bacteria and parasites such as Babesia spp. and Plasmodium spp. are major threats of spreading diseases through transfusion...
  3. Tick Midgut Proteins Critical for Borrelia Transmission
    Sukanya Narasimhan; Fiscal Year: 2010
    ..burgdorferi (agent of Lyme disease), Anaplasma phagocytophilum (agent of human granulocytic ehrlichiosis) and Babesia microti (agent of human babesiosis) among other pathogens. A. phagocytophilum and B...
  4. The role of Variable Erythrocyte Surface Antigen (VESA1) proteins in Babesia bovi
    KERRY SUE SONDGEROTH; Fiscal Year: 2011
    ..provided by applicant): This proposal will investigate virulence mechanisms of cytoadherence/sequestration using Babesia bovis as a natural host model system. Virulent B...
  5. Babesiosis Emergence in the United States
    MARIA ANA DIUK-WASSER; Fiscal Year: 2013
    ..Merit: Human babesiosis is a rapidly emerging tick-borne zoonosis in the United States caused by the protozoan Babesia microti and transmitted by Ixodes scapularis, the Lyme disease vector...
  6. Babesiosis: An Emerging Infectious Threat to Transfusion Medicine
    Cheryl Ann Lobo; Fiscal Year: 2013
    ..The rodent parasite, Babesia microti and the bovine pathogen, Babesia divergens are responsible for most of the human infections that have ..
  7. R&D- MEDICAL: BIOMEDICAL (BASIC RESEARCH)
    Andrew Levin; Fiscal Year: 2012
    This project is aimed at the development of an enzyme immunoassay (ELISA) for screening blood for antibodies to Babesia microti...
  8. Transfusion Infection Pediatric Prospective Study (TRIPPS)
    NAOMI L LUBAN; Fiscal Year: 2011
    ..These include several unique molecular assays: microarray technology using a pathogen chip to monitor babesia, malaria species, trypanosoma, borrelia and other agents, as well as viral blast discovery, using sequence ..
  9. The role of Variable Erythrocyte Surface Antigen (VESA1) proteins in Babesia bovi
    KERRY SUE SONDGEROTH; Fiscal Year: 2013
    ..provided by applicant): This proposal will investigate virulence mechanisms of cytoadherence/sequestration using Babesia bovis as a natural host model system. Virulent B...
  10. Immunoassay for diagnosis of Babesia infection
    ANDREW E LEVIN; Fiscal Year: 2013
    ..provided by applicant): This project is aimed at development of an enzyme immunoassay (EIA) for antibodies to Babesia for use as a clinical diagnostic test...
  11. Babesiosis as a model of age-related immunosenescence
    Henry H Wortis; Fiscal Year: 2012
    ..We developed a mouse model of human babesiosis due Babesia microti, an emerging infection particularly severe in the aged...
  12. A prospective evaluation of chronic B.microti infection in seroreactive blood don
    EVAN MARTIN BLOCH; Fiscal Year: 2013
    ..by applicant): Babesiosis is a tick-borne, intraerythrocytic protozoan infection, caused by members of the Babesia genus...
  13. Coinfection of Tick-borne Diseases in Areas of Wisconsin
    DIANE CAPORALE; Fiscal Year: 2001
    ..The genes targeted will be OspB for B. burgdorferi, the 16S-like gene for Babesia microti and the 1 6S rRNA gene for Ehrlichia (HGE)...
  14. Ninth International Congress on Toxoplasmosis
    Boris Striepen; Fiscal Year: 2007
    ..and pathogenesis of several important human and[unreadable] veterinary parasites including Plasmodium (malaria), Babesia, Theileria,[unreadable] Cryptosporidium (appendix B pathogen), Cyclospora, Neospora, Eimeria, and Isospora...
  15. NOVEL ANTIGENS FOR THE SERODIAGNOSIS OF HUMAN BABESIOSIS
    Raymond Houghton; Fiscal Year: 2001
    ..of tick-borne infections has shown that many individuals infected with Lyme disease have co-infections with Babesia microti (agent of human babesiosis) and Ehrlichia, both of which are potentially fatal in immunocompromised ..
  16. Defining the novel eukaryotic biology of the Apicomplexan plastid
    Ellen Yeh; Fiscal Year: 2013
    ..in two important human pathogens: Plasmodium spp parasites, a leading global infectious disease killer, and Babesia spp parasites, an emerging human infection that threatens the transfusion blood supply...
  17. NATURAL HISTORY OF BABESIOSIS
    Peter Wettstein; Fiscal Year: 1999
    The blood parasite Babesia microti and the spirochetal agent of Lyme disease, B. burgdorferi, are both transmitted by the deer tick, Ixodes dammini ( also called I...
  18. TAS::75 0872::TAS SCREENING AND CONFIRMATORY TESTS FOR HUMAN BABESIA SBIR PHASE
    Andrew Levin; Fiscal Year: 2010
    ..illness due to infection of red blood cells by various species of protozoan parasites belonging to the genus Babesia. Most human infections reported in the United States are caused by B...
  19. Rapid Detection and Identification of Zoonotic Pathogens
    John Dunn; Fiscal Year: 2007
    ..as Yersinia pestis, Francisella tularensis, Rickettsia ricketsii and other human pathogens such as Ehrlichia and Babesia species...
  20. RISK OF TBE IN NORTH AMERICA FOCI OF LYME DISEASE
    Andrew Spielman; Fiscal Year: 1992
    ..abundance with the prevalence of spirochetal and of viral infection in the vector; (3) measure the prevalence of Babesia microti and of Ba...
  21. TRANSMISSION OF GRANULOCYTIC EHRLICHIOSIS
    Sam Telford; Fiscal Year: 2000
    ..outbred and inbred mice, as well as Peromyscus leucopus, the main enzootic reservoir of Borrelia burgdorferi and Babesia microti in the northeastern U.S...
  22. DEVELOPMENT OF PCR BASED ASSAY FOR BABESIOSIS
    BITA NAKHAI; Fiscal Year: 1999
    ..The performance of this assay will be validated on confirmed Babesia-infected patients and on normal controls...
  23. Vaccination Against Ixodes scapularis Tick Bites
    Raymond Koski; Fiscal Year: 2001
    ..burgdorferi, the agent of human granulocytic ehrlichiosis, and Babesia microti...
  24. Development of Paratransgenic ticks for Disease Control
    Ulrike Munderloh; Fiscal Year: 2001
    ..8 new human pathogens have been described in the last 15 years, but they also include viruses, ehrlichias and Babesia. Novel, efficient, specific and environmentally acceptable methods that interfere with disease transmission by ..
  25. Vaccination Against Ixodes scapularis Tick Bites
    Michel Ledizet; Fiscal Year: 2003
    ..burgdorferi, Babesia microti, and the agent of human granulocytic ehrlichiosis...
  26. MOLECULAR GENETIC MARKERS FOR TICK VECTORS
    HARRY HUTCHESON; Fiscal Year: 2002
    ..g., Babesia), viruses (e.g., tick-borne encephalitis), and bacteria (e.g...
  27. TICK-BORNE DISEASE PANEL TEST
    Andrew Levin; Fiscal Year: 2000
    ..disease test will be the first commercial kit available to clinical laboratories for serodiagnosis of HGE, HME, Babesia, RMSF and Lyme disease...
  28. The Role of NKG2D/DAP10 in Toxoplasma gondii Infection
    RACHEL MARGARET PRESTI; Fiscal Year: 2010
    ..consist of numerous protozoa which cause disease, including Plasmodium, Toxoplasma, Cryptosporidia, and Babesia. Toxoplasma gondii is a Category B Priority pathogen which has an excellent small animal model, and is amenable ..
  29. Mechanisms controlling babesial antigenic variation
    DAVID ALLRED; Fiscal Year: 2003
    DESCRIPTION (provided by the applicant): Babesia bovis is a protozoan intraerythrocytic parasite that establishes persistent infections of extremely long duration...
  30. IDENTIFICATION OF BABESIA IMMUNOGENS WITH TH CEL
    Wendy Brown; Fiscal Year: 2000
    ..The pathology of-Babesia bovis infection in cattle is very similar to that caused by Plasmodium falciparum infections in humans, and is ..
  31. EPITOPE DISCOVERY--NEW ROUTE TO VACCINES
    George Smith; Fiscal Year: 2002
    ..Using a second model system--the cattle disease caused by the tick-borne, malaria-like parasite Babesia bovis--we will show how antigenic peptides can be screened in vitro for the likelihood of protective value...
  32. RP FALCIPARUM DHFR IN DRUG SCREENING
    CAROL SIBLEY; Fiscal Year: 1999
    ..human parasites, Toxoplasma, Pneumocystis, Cryptosporidium or the agricultural parasites, Eimeria, Theileria or Babesia. PROPOSED COMMERCIAL APPLICATION: Information will be generated which will greatly decrease the risk of quick ..
  33. MECHANISMS OF PENETRATION OF RBC BY PROTOZOA
    Peter Ward; Fiscal Year: 1980
    The in vitro penetration of human red cells by Babesia rodhaini will be studied with reference to the requirements for complement, immune adherence receptor, and surface antigens...
  34. Comparison of US and European Babesia divergens Isolates
    Patricia Holman; Fiscal Year: 2004
    DESCRIPTION (provided by the applicant): Babesia divergens is a tick transmitted hemoprotozoan parasite that causes human Babesiosis in Europe. Neither B. divergens nor its vector tick are indigenous to the U.S...
  35. HEALTH BURDERN OF COINFECTING DEER ASSOCIATED ZOONOSES
    Peter Krause; Fiscal Year: 2001
    ..The density of deer will be estimated in each site. This proposed effort will help define the health burden imposed on people residing in proximity to deer and will contribute to diagnosis and case-management of apparent Lyme disease. ..
  36. Topical Antibiotics to Prevent Lyme Disease
    Gary Wormser; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  37. Genetic Characterization and Biology of Plague from Multiple Foci
    David Wagner; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  38. Generation of babesial surface protein diversity
    SHAWN BERENS; Fiscal Year: 2006
    ..The hemoparasite model we will use for this research is infection of cattle with Babesia bovis. For B...
  39. Gene expression of Borrelia during Babesia coinfection
    James Coleman; Fiscal Year: 2004
    Coinfection with Borrelia burgdorferi and Babesia microti is a clinically documented, emerging public health concern in the Northeastern United States...
  40. LYME ARTHRITIS: A NEW EPIDEMIC DISEASE
    Allen C Steere; Fiscal Year: 2010
    ..Furthermore, this work brings us closer to the long-term goal of direct comparisons of antigens in Lyme arthritis and rheumatoid arthritis synovia. ..
  41. TOXOPLASMA DEVELOPMENT AND CELL CYCLE
    Kami Kim; Fiscal Year: 2002
    ..These will be the initial experiments in a long-term effort to define the role of cell cycle regulation in Toxoplasma tachyzoite-bradyzoite differentiation and virulence. ..
  42. The Role of Babesia bovis MSA-1 in Erythrocyte Invasion
    Tanya LeRoith; Fiscal Year: 2004
    Apicomplexan parasites in the genera Babesia and Plasmodium infect mature erythocytes and cause disease in animals and humans...
  43. Proximal determinants of risk for tularemia outbreaks
    Sam Telford; Fiscal Year: 2004
    ..tularensis in the environment; and, ultimately, a better understanding of F. tularensis-host interactions. ..
  44. A Therapeutic Target for Microsporidiosis
    Louis Weiss; Fiscal Year: 2007
    ..In addition, the approaches and methods developed in this R21 should also prove useful for studies on methionine aminopeptidases as therapeutic targets in other pathogenic protists. [unreadable] [unreadable] [unreadable]..
  45. C.elegans as a model system forC.neoformans pathogenesis
    Eleftherios Mylonakis; Fiscal Year: 2007
    ..Because C. neoformanshas similarities with other pathogenic yeasts, we expect that our findings will facilitate the study of fungus/host interaction in general. ..
  46. Second International Workshop on Microsporidia from Vertebrate and Invertebrate H
    Louis Weiss; Fiscal Year: 2007
    ..Overall, the goal of this[unreadable] congress is to foster the exchange of information between these diverse groups of[unreadable] scientists leading to advances in research on these emergent pathogens. ..
  47. BIOLOGY AND CONTROL OF LYME DISEASE BORRELIA
    Alan Barbour; Fiscal Year: 2004
    ..burgdorferi, its transmission, and reservoir host immunize responses. The results may also have relevance for the control of other vector-bone zoonotic diseases and perhaps for development of novel methods for vaccine delivery. ..
  48. Improved DNA Polymerases for Genomic Sequencing
    Thomas Schoenfeld; Fiscal Year: 2008
    ..One has been studied in detail and, as expected, it has characteristics that are expected to improve sequencing. [unreadable] [unreadable] [unreadable]..
  49. SERINE PROTEINASES IN APICOMPLEXAN PARASITES
    Kami Kim; Fiscal Year: 2009
    ..In addition to illuminating the function and biology of T. gondii secretory organelles, these studies will determine whether subtilases are a viable chemotherapeutic target for treatment of human infections with Apicomplexan parasites. ..
  50. TOXOPLASMA ENCEPHALITIS IN AIDS: BRADYZOITE REGULATION
    Louis Weiss; Fiscal Year: 2009
    ....
  51. Purine salvage as a chemotherapeutic target in malaria
    Kami Kim; Fiscal Year: 2002
    ..Inhibitors designed in the Schramm and Grubmeyer laboratories will be tested against P. falciparum cultured in human erythrocytes and in mice infected with P. yoelii, a lethal form of mouse malaria. ..
  52. Perpetuation of Francisella tularensis
    Sam R Telford; Fiscal Year: 2010
    ..Taken together, these observations will provide a basis for understanding how the agent of tularemia is perpetuated on Martha's Vineyard, and why pneumonic human disease is prevalent there. ..