plasmodium malariae

Summary

Summary: A protozoan parasite that occurs primarily in subtropical and temperate areas. It is the causal agent of quartan malaria. As the parasite grows it exhibits little ameboid activity.

Top Publications

  1. pmc Identification of Plasmodium malariae, a human malaria parasite, in imported chimpanzees
    Toshiyuki Hayakawa
    Laboratory of Malariology, International Research Center of Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
    PLoS ONE 4:e7412. 2009
  2. ncbi A large focus of naturally acquired Plasmodium knowlesi infections in human beings
    Balbir Singh
    Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Kuching, Sarawak, Malaysia
    Lancet 363:1017-24. 2004
  3. pmc Plasmodium malariae: parasite and disease
    William E Collins
    Centers for Disease Control and Prevention, National Center for Zoonotic, Vector Borne and Enteric Diseases, Division of Parasitic Diseases, Chamblee, GA 30341, USA
    Clin Microbiol Rev 20:579-92. 2007
  4. pmc Comparative population structure of Plasmodium malariae and Plasmodium falciparum under different transmission settings in Malawi
    Marian C Bruce
    Division of Infection and Immunity, Institute of Biomedical and Life Sciences, Level 5, Glasgow Biomedical Research Centre, Glasgow University, 120 University Place, Glasgow, G12 8TA, UK
    Malar J 10:38. 2011
  5. pmc Deaths due to Plasmodium knowlesi malaria in Sabah, Malaysia: association with reporting as Plasmodium malariae and delayed parenteral artesunate
    Giri S Rajahram
    Infectious Diseases Department, Queen Elizabeth Hospital, Karung Berkunci No, 2029, Jalan Penampang, Kota Kinabalu, 88560 Sabah, Malaysia
    Malar J 11:284. 2012
  6. pmc In vivo and in vitro efficacy of chloroquine against Plasmodium malariae and P. ovale in Papua, Indonesia
    H Siswantoro
    National Institute of Health Research and Development, Jakarta, Indonesia
    Antimicrob Agents Chemother 55:197-202. 2011
  7. pmc Plasmodium malariae in Bangladesh
    W Rahman
    Chittagong Medical College Hospital, Chittagong, Bangladesh
    Trans R Soc Trop Med Hyg 104:78-80. 2010
  8. pmc Plasmodium falciparum and P. malariae epidemiology in a West African village
    C Boudin
    , , La Tronche, France
    Bull World Health Organ 69:199-205. 1991
  9. ncbi High prevalence and gender bias in distribution of Plasmodium malariae infection in central east-coast India
    G Dhangadamajhi
    Regional Medical Research Centre ICMR, Bhubaneswar 751023, Orissa, India
    Trop Biomed 26:326-33. 2009
  10. ncbi A case of imported malaria: the first report of a Plasmodium malariae infection in Sri Lanka after 37 years
    H A C Hapuarachchi
    Department of Parasitology, Faculty of Medicine, PO Box 6, Thalagolla Road, Ragama, Sri Lanka
    Ceylon Med J 53:53-4. 2008

Detail Information

Publications187 found, 100 shown here

  1. pmc Identification of Plasmodium malariae, a human malaria parasite, in imported chimpanzees
    Toshiyuki Hayakawa
    Laboratory of Malariology, International Research Center of Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
    PLoS ONE 4:e7412. 2009
    ..Using the sequences of small subunit rRNA and the mitochondrial genome, we identified infection of Plasmodium malariae, a human malaria parasite, in two chimpanzees that were imported about thirty years ago...
  2. ncbi A large focus of naturally acquired Plasmodium knowlesi infections in human beings
    Balbir Singh
    Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Kuching, Sarawak, Malaysia
    Lancet 363:1017-24. 2004
    ..cases in 1999 for the Kapit division of Malaysian Borneo had routinely been identified by microscopy as Plasmodium malariae, although these infections appeared atypical and a nested PCR assay failed to identify P malariae DNA...
  3. pmc Plasmodium malariae: parasite and disease
    William E Collins
    Centers for Disease Control and Prevention, National Center for Zoonotic, Vector Borne and Enteric Diseases, Division of Parasitic Diseases, Chamblee, GA 30341, USA
    Clin Microbiol Rev 20:579-92. 2007
    A review of the life history of Plasmodium malariae, the quartan malaria parasite of humans, is presented...
  4. pmc Comparative population structure of Plasmodium malariae and Plasmodium falciparum under different transmission settings in Malawi
    Marian C Bruce
    Division of Infection and Immunity, Institute of Biomedical and Life Sciences, Level 5, Glasgow Biomedical Research Centre, Glasgow University, 120 University Place, Glasgow, G12 8TA, UK
    Malar J 10:38. 2011
    Described here is the first population genetic study of Plasmodium malariae, the causative agent of quartan malaria. Although not as deadly as Plasmodium falciparum, P...
  5. pmc Deaths due to Plasmodium knowlesi malaria in Sabah, Malaysia: association with reporting as Plasmodium malariae and delayed parenteral artesunate
    Giri S Rajahram
    Infectious Diseases Department, Queen Elizabeth Hospital, Karung Berkunci No, 2029, Jalan Penampang, Kota Kinabalu, 88560 Sabah, Malaysia
    Malar J 11:284. 2012
    ..malaria in Sabah, Malaysia, but is morphologically indistinguishable from and still commonly reported as Plasmodium malariae, despite the paucity of this species in Sabah...
  6. pmc In vivo and in vitro efficacy of chloroquine against Plasmodium malariae and P. ovale in Papua, Indonesia
    H Siswantoro
    National Institute of Health Research and Development, Jakarta, Indonesia
    Antimicrob Agents Chemother 55:197-202. 2011
    Reports of potential drug-resistant strains of Plasmodium malariae in western Indonesia raise concerns that chloroquine resistance may be emerging in P. malariae and P. ovale...
  7. pmc Plasmodium malariae in Bangladesh
    W Rahman
    Chittagong Medical College Hospital, Chittagong, Bangladesh
    Trans R Soc Trop Med Hyg 104:78-80. 2010
    We describe a 32-year-old Bangladeshi male presenting with severe malaria caused by a mono-infection with Plasmodium malariae. Rosetting of infected and uninfected erythrocytes, a putative virulence factor in falciparum malaria, was ..
  8. pmc Plasmodium falciparum and P. malariae epidemiology in a West African village
    C Boudin
    , , La Tronche, France
    Bull World Health Organ 69:199-205. 1991
    ..falciparum-infected bites per year but only 22 of P. malariae. The P. falciparum parasite indices were maximum during the middle of the rainy season (August), while those for P. malariae reached a peak during the dry season (February)...
  9. ncbi High prevalence and gender bias in distribution of Plasmodium malariae infection in central east-coast India
    G Dhangadamajhi
    Regional Medical Research Centre ICMR, Bhubaneswar 751023, Orissa, India
    Trop Biomed 26:326-33. 2009
    ..Malaria prevalence was 81.4% and 43.4% by PCR and microscopy respectively. Moreover, while PCR detected Plasmodium malariae DNA in 108 (44.6%), microscopic examination detected only 20 (8...
  10. ncbi A case of imported malaria: the first report of a Plasmodium malariae infection in Sri Lanka after 37 years
    H A C Hapuarachchi
    Department of Parasitology, Faculty of Medicine, PO Box 6, Thalagolla Road, Ragama, Sri Lanka
    Ceylon Med J 53:53-4. 2008
    ..The history strongly indicated that the infection had been acquired from Malawi. The patient had liver dysfunction and a transient glomerulonephritis, both of which subsided with antimalarial treatment...
  11. ncbi Transfusion-transmitted malaria: case report of asymptomatic donor harboring Plasmodium malariae
    Patricia Scuracchio
    Banco de Sangue de Sao Paulo, Sao Paulo, SP, Brasil
    Rev Inst Med Trop Sao Paulo 53:55-9. 2011
    ..Thick blood smears confirmed Plasmodium malariae. All donors lived in Sao Paulo and one of them (Donor 045-0) showed positive hemoscopy and PCR...
  12. ncbi Anopheles darlingi bionomics and transmission of Plasmodium falciparum, Plasmodium vivax and Plasmodium malariae in Amerindian villages of the Upper-Maroni Amazonian forest, French Guiana
    Romain Girod
    Medical Entomology Unit, Institut Pasteur de la Guyane, Cayenne Cedex, Guyane Francaise
    Mem Inst Oswaldo Cruz 103:702-10. 2008
    ..A total of 14 An. darlingi were found infected with Plasmodium falciparum, Plasmodium vivax or Plasmodium malariae. The annual circumsporozoite indices were 0.15, 0.14 and 0...
  13. pmc Plasmodium malariae in Haitian refugees, Jamaica
    John F Lindo
    University of the West Indies, Kingston, Jamaica
    Emerg Infect Dis 13:931-3. 2007
    ..malariae. PCR confirmed the P. malariae and P. falciparum but not P. vivax infections. DNA sequencing and rRNA gene sequences showed transmission of P. malariae. This report confirms that P. malariae is still being transmitted in Haiti...
  14. ncbi Multiplex real-time PCR detection of P. falciparum, P. vivax and P. malariae in human blood samples
    Vincent Veron
    Laboratoire Hospitalo universitaire de Parasitologie et Mycologie Médicale, Equipe EA3593, UFR de Medecine, Universite des Antilles et de la Guyane, Cayenne, French Guiana
    Exp Parasitol 121:346-51. 2009
    ..PCR assays were developed to diagnose three human parasites: Plasmodium falciparum, Plasmodium vivax and Plasmodium malariae. TaqMan duplex real-time PCR was evaluated in 263 blood samples of suspected malaria patients by comparing ..
  15. pmc Detection of four Plasmodium species in blood from humans by 18S rRNA gene subunit-based and species-specific real-time PCR assays
    Mathieu Rougemont
    Institute of Microbiology, University Hospital of Lausanne, Switzerland
    J Clin Microbiol 42:5636-43. 2004
    ..This suggests a role of quantitative PCR for the monitoring of patients receiving antimalaria therapy...
  16. ncbi [Relapse of Plasmodium malariae malaria 20 years after living in an endemic area]
    Emna Siala
    Laboratoire de parasitologie clinique, Institut Pasteur de Tunis
    Presse Med 34:371-2. 2005
    ..Malaria has been eradicated in Tunisia since 1979. Although it continues to be evoked in the case of fever after travel to an endemic zone, its diagnosis is however difficult during relapses, notably when they are delayed...
  17. pmc Isolation and characterization of the MSP1 genes from Plasmodium malariae and Plasmodium ovale
    Larry Birkenmeyer
    Abbott Diagnostics, Infectious Diseases R and D, Dept 09NB, Bldg AP20, 100 Abbott Park Road, Abbott Park, IL 60064 6015, USA
    Am J Trop Med Hyg 82:996-1003. 2010
    ..and Plasmodium vivax, this gene has not been identified for the other two major human-infectious species, Plasmodium malariae and Plasmodium ovale. MSP1 genes from these two species were isolated from Cameroon blood donor samples...
  18. ncbi Evidence for the efficacy of artesunate in asymptomatic Plasmodium malariae infections
    Steffen Borrmann
    Medical Research Unit, Albert Schweitzer Hospital, Lambarene, B P 118, Gabon
    J Antimicrob Chemother 50:751-4. 2002
    This study evaluated the efficacy and safety of a 3-day course of artesunate (4 mg/kg/day) for asymptomatic Plasmodium malariae infections...
  19. ncbi Plasmodium species co-infection as a cause of treatment failure
    A Smith
    Department of General Medicine, Royal North Shore Hospital, NSW, Australia
    Travel Med Infect Dis 9:306-9. 2011
    We report a case of Plasmodium falciparum and Plasmodium malariae coinfection with associated failure of clinical response to artemether + lumefantrine therapy...
  20. ncbi Re-emergence of Plasmodium malariae in Trinidad, West Indies
    D D Chadee
    Insect Vector Control Division, Ministry of Health, St Joseph, Trinidad
    Ann Trop Med Parasitol 93:467-75. 1999
    A focus of Plasmodium malariae infection has recently occurred on the island of Trinidad, some 30 years after a successful eradication programme. Examination of bloodsmears revealed 22 cases of P...
  21. ncbi [Congenital malaria due to Plasmodium falciparum and Plasmodium malariae]
    W Zenz
    Universitätsklinik für Kinder und Jugendheilkunde Graz
    Wien Klin Wochenschr 112:459-61. 2000
    ..3 g/l. In the blood smear Plasmodium falciparum and Plasmodium malariae were detected...
  22. ncbi Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor
    Jose C Clemente
    Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, USA
    Acta Crystallogr D Biol Crystallogr 62:246-52. 2006
    ..Inhibition analysis of PmPM4 also suggests the potential for allophenylnorstatine-based compounds to be effective against all species of malaria infecting humans and for the future development of a broad-based inhibitor...
  23. pmc Plasmodium malariae infection boosts Plasmodium falciparum gametocyte production
    F Ellis McKenzie
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Trop Med Hyg 67:411-4. 2002
    ..of malaria therapy patients sequentially or simultaneously inoculated with Plasmodium falciparum and Plasmodium malariae. Gametocyte production was enhanced in P. falciparum by prior or concurrent P...
  24. ncbi [The epidemiology of malaria in the southwestern forests of the Ivory Coast (Tai region)]
    I Nzeyimana
    Centre Pierre Richet, 01 B P 1500, Bouaké 01, Cote d Ivoire
    Bull Soc Pathol Exot 95:89-94. 2002
    ..This deterioration has probably been caused by demographic pressure resulting from internal and foreign immigration to the Taï region and more especially by the influx of Liberian refugees...
  25. ncbi Increased Plasmodium falciparum gametocyte production in mixed infections with P. malariae
    J Teun Bousema
    Department of Medical Microbiology, Radboud University, Nijmegen Medical Centre, Nijmegen, The Netherlands
    Am J Trop Med Hyg 78:442-8. 2008
    ..15, 95% confidence interval = 0.99-4.65 and 2.39, 1.58-3.63) but not in a study from Nigeria. These data suggest that co-infection with P. malariae is correlated with increased P. falciparum gametocytemia...
  26. ncbi Identification and typing of Cameroonian isolates of P. malariae using monoclonal antibodies against P. brasilianum
    Sedigheh Zakeri
    Wolfson Unit of Tropical Immunology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom
    Acta Trop 99:97-101. 2006
    ..brasilianum were used to demonstrate, for the first time, antigenic diversity in natural populations of Plasmodium malariae isolates and as diagnostic tool to detect low parasitaemia P. malariae infection...
  27. pmc Genetic analysis of the dihydrofolate reductase-thymidylate synthase gene from geographically diverse isolates of Plasmodium malariae
    Naowarat Tanomsing
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Antimicrob Agents Chemother 51:3523-30. 2007
    b>Plasmodium malariae, the parasite responsible for quartan malaria, is transmitted in most areas of malaria endemicity and is associated with significant morbidity...
  28. pmc Characterization and application of multiple genetic markers for Plasmodium malariae
    M C Bruce
    Division of Infection and Immunity, Institute of Biomedical and Life Sciences, Glasgow Biomedical Research Centre, Glasgow University, 120 University Place, Glasgow G12 8TA, UK
    Parasitology 134:637-50. 2007
    b>Plasmodium malariae, a protozoan parasite that causes malaria in humans, has a global distribution in tropical and subtropical regions and is commonly found in sympatry with other Plasmodium species of humans...
  29. ncbi Cross-species regulation of Plasmodium parasitemia in semi-immune children from Papua New Guinea
    Marian C Bruce
    Institute of Biomedical and Life Sciences, Division of Infection and Immunity, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    Trends Parasitol 19:271-7. 2003
    ..A model of how multiple immune responses could act in concert to explain these within-host dynamics are discussed here in relation to observed epidemiological patterns of mixed-species infections...
  30. ncbi [Epidemiology of malaria in a village of Sudanese savannah area in Mali (Bancoumana). 2. Entomo-parasitological and clinical study ]
    A Dolo
    Dép d épidémiologie des affections parasitaires, Faculte de Medecine, de pharmacie et d odonto stomalogie, BP 1805, Bamako, Mali
    Bull Soc Pathol Exot 96:308-12. 2003
    ..This reduction of parasitologic index between 1993 and 1994 may be related to an increase of anti-malarial drug use in the population. Our results show that malaria is hyperendemic in the village of Bancoumana...
  31. ncbi High prevalence of Plamodium malariae infections in a Brazilian Amazon endemic area (Apiacás-Mato Grosso State) as detected by polymerase chain reaction
    Kézia K G Scopel
    Departamento de Parasitologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Av Antonio Carlos, 6627, 31270 901 Belo Horizonte, Minas Gerais, Brazil
    Acta Trop 90:61-4. 2004
    b>Plasmodium malariae is commonly confounded with Plasmodium vivax at the microscopic examination of thick blood smear...
  32. pmc Malaria clusters among illegal Chinese immigrants to Europe through Africa
    Zeno Bisoffi
    Centro per le Malattie Tropicali, Ospedale S Cuore, Negrar, Verona, Italy
    Emerg Infect Dis 9:1177-8. 2003
    ..A further cluster of 12 was reported in August, 2002. Several immigrants traveled by air, making the risk of introducing sudden acute respiratory syndrome a possibility should such illegal immigrations continue...
  33. ncbi Plasmodium malariae infection in spite of previous anti-malarial medication
    Irmela Müller-Stöver
    Tropenmedizinische Ambulanz, Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Universitatsklinikum Dusseldorf, Heinrich Heine Universitat, Moorenstr 5, 40225 Dusseldorf, Germany
    Parasitol Res 102:547-50. 2008
    b>Plasmodium malariae is regarded as usually being susceptible to all anti-malarials whether applied for prophylaxis or treatment. We report on three cases of P...
  34. pmc Plasmodium malariae and Plasmodium ovale--the "bashful" malaria parasites
    Ivo Mueller
    Papua New Guinea Institute of Medical Research, Madang MAD511, Papua New Guinea
    Trends Parasitol 23:278-83. 2007
    Although Plasmodium malariae was first described as an infectious disease of humans by Golgi in 1886 and Plasmodium ovale identified by Stevens in 1922, there are still large gaps in our knowledge of the importance of these infections as ..
  35. pmc Plasmodium malariae blood-stage dynamics
    F E McKenzie
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA
    J Parasitol 87:626-37. 2001
    ..S. neurosyphilis patients infected with the USPHS strain of Plasmodium malariae, for malariatherapy, focusing on the 84 charts for which more than 35 days of patency preceded intervention ..
  36. ncbi Monkeys of the rainforest in French Guiana are natural reservoirs for P. brasilianum/P. malariae malaria
    T Fandeur
    Laboratoire de Parasitologie Moleculaire, Institut Pasteur de Guyane, Cayenne, French Guiana
    Parasitology 120:11-21. 2000
    ..These results have implications for the interpretation of the current epidemiological situation in French Guiana...
  37. ncbi Cross-species interactions between malaria parasites in humans
    M C Bruce
    Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford, OX1 3FY, UK
    Science 287:845-8. 2000
    ..This regulation, in combination with species- and genotype-specific immune responses, results in nonindependent, sequential episodes of infection with each species...
  38. ncbi Acute renal failure in Plasmodium malariae infection
    S Neri
    Department of Internal Medicine, Unit of Nephrology, University of Catania, Catania, Italy
    Neth J Med 66:166-8. 2008
    ..The infecting species was Plasmodium malariae, and the patient developed acute renal failure, severe thrombocytopenia, and hepatic failure...
  39. ncbi Extended clearance time after treatment of infections with Plasmodium malariae may not be indicative of resistance to chloroquine
    Willlam E Collins
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, U S Public Health Service, Department of Health and Human Services, Atlanta, Georgia 30341 3724, USA
    Am J Trop Med Hyg 67:406-10. 2002
    A retrospective examination was made of archival data on the response of Plasmodium malariae infections in humans to chloroquine. The clearance time for P. malariae was longer than that for P. falciparum and P. vivax. Of 100 P...
  40. ncbi Association of haptoglobin levels with age, parasite density, and haptoglobin genotype in a malaria-endemic area of Gabon
    Freya J I Fowkes
    Peter Medawar Building for Pathogen Research and Department of Zoology, University of Oxford, Oxford, United Kingdom
    Am J Trop Med Hyg 74:26-30. 2006
    ..This suggests that in the presence of greater parasite-induced hemolysis, older children are capable of increased production of Hp. Sickle cell trait and ABO blood group was not associated with Hp levels in this population...
  41. ncbi Rapid immunochromatographic malarial antigen detection unreliable for detecting Plasmodium malariae and Plasmodium ovale
    M P Grobusch
    Department of Parasitology, Institute of Tropical Medicine, Eberhard Karls University, Wilhelmstrasse 27, 72074 Tubingen, Germany
    Eur J Clin Microbiol Infect Dis 21:818-20. 2002
    ..tests for the rapid detection of plasmodial antigen in cases of infection with Plasmodium ovale and Plasmodium malariae, the products were evaluated in four centers and a search of the relevant literature was performed...
  42. ncbi How prevalent are Plasmodium ovale and P. malariae in East Asia?
    F Kawamoto
    Department of International Health, Nagoya University School of Medicine, Showa, Nagoya, Japan
    Parasitol Today 15:422-6. 1999
    Plasmodium ovale and Plasmodium malariae, two of the four human malaria parasites, are usually found at very low prevalence in East Asia, even in areas with intense malaria transmission...
  43. ncbi Short report: prevalence and chloroquine sensitivity of Plasmodium malariae in Madagascar
    Céline Barnadas
    Parasitology and Tropical Medicine, University Lyon 1, Lyon, France
    Am J Trop Med Hyg 77:1039-42. 2007
    ..The aims were (i) to update our knowledge of the burden of Plasmodium malariae infection and (ii) to assess the therapeutic efficacy of chloroquine for uncomplicated quartan malaria...
  44. ncbi Unusual plasmodium malariae-like parasites in southeast Asia
    Fumihiko Kawamoto
    Department of International Health, Nagoya University School of Medicine, Japan
    J Parasitol 88:350-7. 2002
    During malaria surveys in Myanmar, 2 peculiar forms of Plasmodium malariae-like parasites were found. The morphologies of their early trophozoite stages were distinct from that of the typical P...
  45. ncbi Malaria in Wanokaka and Loli sub-districts, West Sumba District, East Nusa Tenggara Province, Indonesia
    Din Syafruddin
    Eijkman Institute for Molecular Biology, Jakarta, Indonesia
    Am J Trop Med Hyg 74:733-7. 2006
    ..The findings indicate that the malaria incidence and transmission in the area are relatively high and that further exploration is warranted to establish a precise malaria control program...
  46. ncbi [Malaria. Primary symptoms: fever, headache, nausea, vomiting, diarrhea]
    G Schulthess
    Medizinische Poliklinik Universitätsspital Zürich
    Praxis (Bern 1994) 95:255-60; quiz 261. 2006
  47. ncbi Mixed Plasmodium falciparum-Plasmodium malariae infection and hemoglobin SC disease: a case report
    Leonardo Chianura
    Department of Infectious Diseases, Niguarda Ca Granda Hospital, Milano, Italy
    J Travel Med 13:115-8. 2006
    ..We present a case of mixed Plasmodium falciparum-Plasmodium malariae infection complicating HbSC disease in a 34-year-old Ghanaian immigrant...
  48. ncbi Evaluation of a new plate hybridization assay for the laboratory diagnosis of imported malaria in Italy
    A Calderaro
    Department of Pathology and Laboratory Medicine, Section of Microbiology, University of Parma, Parma, Italy
    New Microbiol 27:163-71. 2004
    ..3 P. malariae parasites/microliter and 0.4 P. ovale parasites/microliter of whole blood, respectively. This assay could be successfully applied to the laboratory diagnosis of malaria as a useful aid to microscopy...
  49. ncbi Recombinant expression and enzymatic subsite characterization of plasmepsin 4 from the four Plasmodium species infecting man
    Tang Li
    Department of Pathobiology, University of Florida, P O Box 110880, Gainesville, FL 32611 0880, USA
    Mol Biochem Parasitol 135:101-9. 2004
    Plasmepsin 4 from Plasmodium falciparum and orthologs from Plasmodium malariae, Plasmodium ovale and Plasmodium vivax have been expressed in recombinant form, and properties of the active site of each enzyme characterized by kinetic ..
  50. ncbi Malaria control in Papua New Guinea results in complex epidemiological changes
    Ivo Mueller
    Papua New Guinea Institute of Medical Research, Goroka, Swiss Tropical Institute, Basel, Switzerland
    P N G Med J 48:151-7. 2005
    ..The example of Karimui indicates that unsustained control can lead to changes in malaria patterns that may leave a population worse off...
  51. pmc Diagnosis of mixed Plasmodium malariae and P. vivax infection in a development aid volunteer by examination of bone-marrow specimens by real-time PCR
    Can Imirzalioglu
    Center for Tropical Diseases and Travel Medicine, Hospital of the Justus Liebig University Giessen, Institute of Medical Microbiology, Frankfurter Strasse 107, Giessen, Germany
    J Clin Microbiol 44:2307-10. 2006
    Mixed Plasmodium malariae and P. vivax infections in humans are reported very infrequently. The case of a 27-year-old male who sustained malaria quartana/tertiana caused by an unbalanced mixed P. malariae-P...
  52. ncbi Parasitological and clinical efficacy of standard treatment regimens against Plasmodium falciparum, P. vivax and P. malariae in Papua New Guinea
    Blaise Genton
    Swiss Tropical Institute, Basel, Switzerland
    P N G Med J 48:141-50. 2005
    ....
  53. ncbi Active-site specificity of digestive aspartic peptidases from the four species of Plasmodium that infect humans using chromogenic combinatorial peptide libraries
    Bret B Beyer
    Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, Florida 32610, USA
    Biochemistry 44:1768-79. 2005
    ..Some of these compounds were potent inhibitors of the five plasmepsins, and their possible binding modes were analyzed by computational methods...
  54. ncbi Evaluation of a real-time PCR assay for malaria diagnosis in patients from Vietnam and in returned travellers
    Thi Kim Duy Vo
    Universite de la Mediterranee, EA 864, IFR 48, Marseille, France University of Hue, 20 Le Loi, Hue, Vietnam
    Trans R Soc Trop Med Hyg 101:422-8. 2007
    ..This new real-time PCR is a rapid, accurate and efficient method for malaria diagnosis in returned travellers as well as for epidemiological studies or antimalarial efficiency trials in the field...
  55. ncbi [A history of Malaria from and for a popular point of view]
    D Crotti
    L P in Parassitologia e Microbiologia Medica, Pilonico Paterno 4, 06080 Pianello, Perugia
    Infez Med 13:265-70. 2005
    ..In other words, the author dwells upon the literary, the customary, as well as on the historic and cultural aspects, with special attention to the significance of the popular importance of this problem in Italy...
  56. pmc Detection and identification of human Plasmodium species with real-time quantitative nucleic acid sequence-based amplification
    Petra F Mens
    Koninklijk Instituut voor de Tropen Royal Tropical Institute, KIT Biomedical Research, Meibergdreef 39, 1105 AZ Amsterdam, The Netherlands
    Malar J 5:80. 2006
    ..Rapid diagnostic tests based on Plasmodium antigen detection do often not allow for species discrimination as microscopy does, but also become insensitive at <100 parasites/microl...
  57. pmc Space-time clustering of childhood malaria at the household level: a dynamic cohort in a Mali village
    Jean Gaudart
    Medical Statistics and Informatics Research Team, LIF UMR 6166 CNRS Aix Marseille University, Faculty of Medicine, 27 Bd Jean Moulin 13385 Marseille Cedex 05, France
    BMC Public Health 6:286. 2006
    ..The aim of this study was to identify, spatially and temporally, high-risk zones of malaria, at the household level (resolution of 1 to 3 m)...
  58. ncbi Outpatient treatment of malaria in recently arrived African migrants
    Desmond T Chih
    Department of Microbiology and Infectious Diseases, Royal Perth Hospital, Perth, WA, Australia
    Med J Aust 185:598-601. 2006
    ..To describe the clinical features and management of African migrants recently arrived in Western Australia and subsequently diagnosed with malaria...
  59. ncbi Community-randomized trial of lambdacyhalothrin-treated hammock nets for malaria control in Yanomami communities in the Amazon region of Venezuela
    M Magris
    Centro Amazónico de Investigación y Control de Enfermedades Tropicales Simón Bolivar, Puerto Ayacucho, Estado Amazonas, Venezuela
    Trop Med Int Health 12:392-403. 2007
    ..This is the first community-level epidemiological trial to show that ITHN are highly effective against malaria transmitted by Anopheles darlingi...
  60. ncbi Qualitative comparison of qualitative buffy coat and light microscopy in malaria diagnosis
    A F Fagbenro-Beyioku
    Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Lagos, Nigeria
    Trop Doct 37:60-1. 2007
  61. ncbi [Current data on malaria in metropolitan France]
    M Danis
    Centre National de Référence pour les Maladies d Importation, ISD, 15, rue de l Ecole de Medecine, 75270 Paris
    Med Trop (Mars) 62:214-8. 2002
    ..5% involving Plasmodium ovale and 1.3% involving Plasmodium malariae. Attacks were clinically uncomplicated in 90 to 95% of cases and severe in 2 to 5% including fatal ..
  62. ncbi [Two cases of mixed infection of malaria diagnosed by PCR method]
    Shusaku Haranaga
    First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus
    Kansenshogaku Zasshi 76:571-5. 2002
    ..vivax and Plasmodium malariae. The other was a 54 year-old female suffering from general fatigue...
  63. ncbi Chloroquine for the treatment of uncomplicated malaria in Guyana
    J K Baird
    U S Naval Medical Research Unit 2, American Embassy Jakarta, Fleet Post Office Asia Pacific 96520 8132, U S A
    Ann Trop Med Parasitol 96:339-48. 2002
    ..e. <100 ng/ml). Taken together, the results indicate a high risk of therapeutic failure of CQ against P. falciparum but also indicate that resistance to CQ in P. vivax occurs infrequently in Guyana...
  64. ncbi Molecular characterisation of airport malaria: four cases in France during summer 1999
    S Jafari
    Centre National de Reference pour la Chimiosensibilite du Paludisme, Assistance Publique Hopitaux de Paris, Laboratoire de Parasitologie, Hopital Bichat Claude Bernard, 46, rue Henri Huchard, 75877 Paris, France
    Parasite 9:187-91. 2002
    ..In vitro susceptibility data did not confirm or rule out this hypothesis because isolates had the same profile of susceptibility to the tested drugs...
  65. ncbi Level and dynamics of malaria transmission and morbidity in an equatorial area of South Cameroon
    S Bonnet
    OCEAC, Yaounde, Cameroon
    Trop Med Int Health 7:249-56. 2002
    ..16% and the same morbidity of 0.17-0.5 attacks/person/year. Plasmodium malariae prevalence was 14 vs. 16%...
  66. pmc Minor liver profile dysfunctions in Plasmodium vivax, P. malaria and P. ovale patients and normalization after treatment
    Noppadon Tangpukdee
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Korean J Parasitol 44:295-302. 2006
    ..These minor abnormalities returned to normal within a few weeks after treatment with therapies based on artemisinin derivatives...
  67. pmc Failure to detect Plasmodium vivax in West and Central Africa by PCR species typing
    Richard L Culleton
    Laboratory of Malariology, International Research Centre of Infectious Diseases, Research Institute of Microbial Diseases, Osaka University, Osaka, Japan
    Malar J 7:174. 2008
    ..vivax malaria after visiting this region. An attempt was made, therefore, to detect the presence of P. vivax parasites in blood samples collected from the indigenous populations of west and central Africa...
  68. ncbi Clinical evaluation of antimalarial regimens in Japan
    H Ohtomo
    Department of Parasitology, Gifu University School of Medicine, Japan
    Zentralbl Bakteriol Mikrobiol Hyg A 264:513-20. 1987
    ....
  69. ncbi Imported malaria in Trinidad and Tobago, W.I. (1968-1986)
    D D Chadee
    Insect Vector Control Division, Ministry of Health, Trinidad
    Ann Trop Med Parasitol 83:107-14. 1989
    ..Trinidadians of African and East Indian descent accounted for 78% of all imported malaria cases. Malaria resistance and relapse are discussed. The need to maintain port surveillance is emphasized...
  70. ncbi Epidemiology of highland malaria in western Kenya
    M K Arness
    Disease Epidemiology and Surveillance, Walter Reed Army Medical Center, Washington, DC, USA
    East Afr Med J 80:253-9. 2003
    ....
  71. ncbi Treatment history and treatment dose are important determinants of sulfadoxine-pyrimethamine efficacy in children with uncomplicated malaria in Western Kenya
    Dianne J Terlouw
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    J Infect Dis 187:467-76. 2003
    ..Many age-based dose recommendations need urgent revision, because SP is increasingly used as first-line treatment in sub-Saharan Africa...
  72. ncbi [Treatment of malaria in children: 1. Uncomplicated malaria]
    P Imbert
    Service des Maladies Infectieuses et Tropicales, Hopital d Instruction des armees BEGIN, 69, avenue de Paris, 94163 Saint Mandé, France
    Med Trop (Mars) 62:554-60. 2002
    ..Widespread use of these therapies to prevent the appearance and extension of resistance is now undergoing evaluation...
  73. pmc Epidemiologic aspects of the malaria transmission cycle in an area of very low incidence in Brazil
    Crispim Cerutti
    Department of Social Medicine, Biomedical Center, Federal University of Espirito Santo, Maruípe, Vitoria ES, Brazil
    Malar J 6:33. 2007
    ..Extra-Amazonian autochthonous Plasmodium vivax infections have been reported in mountainous regions surrounded by the Atlantic Forest in Espírito Santo state, Brazil...
  74. ncbi Prevalence and level of antibodies to the circumsporozoite protein of human malaria parasites in five states of the Amazon region of Brazil
    Mercia E Arruda
    Departamento de Imunologia, CPqAM, FIOCRUZ, Recife, PE, Brasil
    Mem Inst Oswaldo Cruz 102:367-71. 2007
    ..vivax-like were more frequent in Rondônia, Pará, and Mato Grosso. The high frequency of reactions to P. malariae in most of the areas suggests that the infection by this Plasmodium species has been underestimated in Brazil...
  75. ncbi Drug treatment of malaria in children
    Chandy C John
    Rainbow Babies and Children s Hospital, Case Western Reserve University, Cleveland, OH, USA
    Pediatr Infect Dis J 22:649-51. 2003
  76. ncbi [Triple malaria infection in twin sisters from the Democratic Republic of Congo]
    G Galeazzi
    Unité de Parasitologie Mycologie, Hôpital Louis Mourier 92701 Colombes, France
    Bull Soc Pathol Exot 96:96-8. 2003
    ..The biological tests results were similar. They responded well to treatment. We point out the difficulty in recognizing the concomitant presence of several species of hematozoaire on blood smear...
  77. ncbi Comparison of Quantitative Buffy Coat technique (QBC) with Giemsa-stained Thick Film (GTF) for diagnosis of malaria
    G O Adeoye
    Department of Zoology, University of Lagos, Akoka, Yaba, Lagos, Nigeria
    Parasitol Int 56:308-12. 2007
    ..However, its speed and ease of use make it an important new tool for the diagnosis of malaria...
  78. ncbi Malaria in Austria 1990-2000
    R Strauss
    Federal Ministry for Social Security and Generations, Section Public Health, Vienna, Austria
    Euro Surveill 8:91-6. 2003
    ..4%) but only half of them (n=367, 48.8%) gave detailed information on the drug used. Data on compliance were obtained for only 45.4% of the cases, with only about 60% of patients completing the full course of prophylaxis...
  79. ncbi Plasmodium malariae in East Timor
    Reg Bragonier
    HealthNet International, Bobonaro District, East Timor
    Southeast Asian J Trop Med Public Health 33:689-90. 2002
    ..vivax, six individuals with P. malariae infection were identified (prevalence 0.57%). We believe these are the first reported cases of P. malariae from the island of Timor...
  80. pmc Evaluation of the intra- and inter-specific genetic variability of Plasmodium lactate dehydrogenase
    Arthur M Talman
    Unité d Epidémiologie Moléculaire, Institut Pasteur in Cambodia 5 Boulevard Monivong BP983, Phnom Penh, Kingdom of Cambodia
    Malar J 6:140. 2007
    ..However a characterization of the efficiency of these tests and the proteins they detect is needed to maximize RDT sensitivity...
  81. ncbi [Clinical evaluation of antimalarial drugs]
    K Tanabe
    Department of Infectious Diseases, University of Tokyo
    Kansenshogaku Zasshi 64:668-73. 1990
    ..Recovery periods from fever and parasitemia were compared between chloroquine and Fansidar cases.(ABSTRACT TRUNCATED AT 250 WORDS)..
  82. pmc High sensitivity detection of Plasmodium species reveals positive correlations between infections of different species, shifts in age distribution and reduced local variation in Papua New Guinea
    Ivo Mueller
    Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea
    Malar J 8:41. 2009
    ..consistently less common than expect in areas co-endemic for Plasmodium falciparum, Plasmodium vivax and Plasmodium malariae. The development of a high-throughput molecular species diagnostic assay now enables routine PCR-based ..
  83. pmc Implementation of a novel PCR based method for detecting malaria parasites from naturally infected mosquitoes in Papua New Guinea
    Arif U Hasan
    Department of International Medical Zoology, Faculty of Medicine, Kagawa University, 1750 1, Ikenobe, Miki, Kita, Kagawa, 761 0793 Japan
    Malar J 8:182. 2009
    ..The objective of this study was to introduce an effective PCR-based method for detecting Plasmodium vivax and Plasmodium falciparum from the field-caught mosquitoes of Papua New Guinea...
  84. pmc Test characteristics of the SD FK80 Plasmodium falciparum/Plasmodium vivax malaria rapid diagnostic test in a non-endemic setting
    Philippe Gillet
    Department of Clinical Medicine, Institute of Tropical Medicine, Nationalestraat 155, B 2000 Antwerp, Belgium
    Malar J 8:262. 2009
    ..The present study assessed its performance in a non-endemic setting...
  85. pmc Malaria--a major health problem within an oil palm plantation around Popondetta, Papua New Guinea
    Bianca Pluess
    Swiss Tropical Institute, Basel, Switzerland
    Malar J 8:56. 2009
    ..This study provides an overview of the malaria epidemiology within an oil palm plantation in Popondetta, south-eastern Papua New Guinea, its implication for the company with its employees and their families and the potential for control...
  86. pmc Malaria in Brazil: an overview
    Joseli Oliveira-Ferreira
    Laboratório de Pesquisa em Malária, Instituto Oswaldo Cruz, FIOCRUZ, Pavilhão Leônidas Deane 5 degrees andar, Av Brasil 4365, Manguinhos, Rio de Janeiro, RJ CEP 21 045 900, RJ Brazil
    Malar J 9:115. 2010
    ..vivax accounts for 83,7% of registered cases, while Plasmodium falciparum is responsible for 16,3% and Plasmodium malariae is seldom observed...
  87. pmc Plasmodium knowlesi malaria in humans is widely distributed and potentially life threatening
    Janet Cox-Singh
    Malaria Research Centre, Faculty of Medicine and Health Sciences, University Malaysia Sarawak, Kuching, Sarawak, Malaysian Borneo
    Clin Infect Dis 46:165-71. 2008
    Until recently, Plasmodium knowlesi malaria in humans was misdiagnosed as Plasmodium malariae malaria. The objectives of the present study were to determine the geographic distribution of P...
  88. ncbi Natural Plasmodium infections in Brazilian wild monkeys: reservoirs for human infections?
    Ana Maria Ribeiro de Castro Duarte
    Laboratório de Bioquímica e Biologia Molecular, Superintendência de Controle de Endemias SUCEN, Secretaria de Estado da Saúde, Rua Paula Souza 166, Sao Paulo, Brazil
    Acta Trop 107:179-85. 2008
    ..3% or 8/71 (5.6% for Plasmodium malariae and 5.6% for Plasmodium vivax) and one specimen was positive for Plasmodium falciparum (1...
  89. pmc Sub-microscopic malaria cases and mixed malaria infection in a remote area of high malaria endemicity in Rattanakiri province, Cambodia: implication for malaria elimination
    Nicolas Steenkeste
    Unité d Epidémiologie Moléculaire, Institut Pasteur du Cambodge, Phnom Penh, Cambodia
    Malar J 9:108. 2010
    ....
  90. ncbi Malaria infection and human evolution
    S Sabbatani
    Infectious Diseases, S Orsola Malpighi Hospital, Bologna Internal Medicine, Budrio General Hospital, Budrio, Italy
    Infez Med 18:54-74. 2010
    ..plasmodia causing malaria have evolved in two ways, in biological and phylogenetic terms: Plasmodium vivax, Plasmodium malariae and Plasmodium ovale appear to have either coevolved with human mankind, or encountered human species ..
  91. pmc Evaluation and optimization of membrane feeding compared to direct feeding as an assay for infectivity
    Mouctar Diallo
    Malaria Research and Training Center, University of Bamako, Bamako, Mali
    Malar J 7:248. 2008
    ..Anopheles gambiae s.l is the main vector responsible of Plasmodium falciparum transmission in Bancoumana and represents about 90% of the laboratory findings, whereas Plasmodium malariae and Plasmodium ovale together represent only 10%.
  92. ncbi Moderate transmission but high prevalence of malaria in Madagascar
    Vincent Robert
    Institut de Recherche pour le Developpement, Antananarivo, Madagascar
    Int J Parasitol 36:1273-81. 2006
    ..falciparum 78.9%, P. vivax 19.4%, Plasmodium malariae 1.0% and Plasmodium ovale 0.7%...
  93. ncbi Plasmepsin 4, the food vacuole aspartic proteinase found in all Plasmodium spp. infecting man
    John B Dame
    Department of Pathobiology, College of Veterinary Medicine, University of Florida, Box 110880, Gainesville, FL 32611 0880, USA
    Mol Biochem Parasitol 130:1-12. 2003
    ..Genes encoding the ortholog of PfPM4 have been cloned from Plasmodium ovale, Plasmodium malariae, and P. vivax. In addition, P...
  94. ncbi Epidemiology of travel-related malaria in a non-malarious area in Saudi Arabia
    Jaffar A Al-Tawfiq
    Internal Medicine Services Division, PO Box 76, Room A 420B, Building 61, Dhahran Health Center, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran 31311, Kingdom of Saudi Arabia
    Saudi Med J 27:86-9. 2006
    ..The study describes the epidemiology of malaria in the Eastern Province of Saudi Arabia and the species of Plasmodium causing the disease and the associated factors...
  95. pmc Evaluation of the SD FK70 malaria Ag Plasmodium vivax rapid diagnostic test in a non-endemic setting
    Philippe Gillet
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    Malar J 8:129. 2009
    ....
  96. pmc PCR-based detection of Plasmodium in Anopheles mosquitoes: a comparison of a new high-throughput assay with existing methods
    Chris Bass
    Department of Biological Chemistry, Center for Sustainable Pest and Disease Management, Rothamsted Research, Harpenden, UK
    Malar J 7:177. 2008
    ..the four malaria-causing Plasmodium species (Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale and Plasmodium malariae) within their mosquito hosts is an essential component of vector control programmes...
  97. ncbi Prevalence of parasitic diseases among nomadic Fulanis of south-eastern Nigeria
    Jude C Anosike
    Nomadic Reseach Program Department of Animal and Environmental Biology, Imo State University, Owerri, PMB 2000 Owerri, Nigeria
    Ann Agric Environ Med 11:221-5. 2004
    ..Of these, 98 (42.4%) were infected with one or more of 14 parasitic species, of which Plasmodium malariae had the highest prevalence (15.3%)...
  98. pmc Evaluation of FRET real-time PCR assay for rapid detection and differentiation of Plasmodium species in returning travellers and migrants
    Innocent Safeukui
    Pôle de Biologie Moléculaire, CHU de Bordeaux, Hopital Pellegrin, Place Amelie Raba Leon, 33076 Bordeaux Cedex, France
    Malar J 7:70. 2008
    ..with simultaneous differentiation of Plasmodium falciparum from the three other Plasmodium species (Plasmodium vivax, Plasmodium ovale and Plasmodium malariae) in febrile returning travellers and migrants was developed and evaluated.
  99. pmc Plasmodium knowlesi from archival blood films: further evidence that human infections are widely distributed and not newly emergent in Malaysian Borneo
    Kim Sung Lee
    Malaria Research Centre, Faculty of Medicine and Health Sciences, Unversiti Malaysia Sarawak, 93150 Kuching, Sarawak, Malaysian Borneo, Malaysia
    Int J Parasitol 39:1125-8. 2009
    Human infections with Plasmodium knowlesi have been misdiagnosed by microscopy as Plasmodium malariae due to their morphological similarities. Although microscopy-identified P...
  100. pmc African apes as reservoirs of Plasmodium falciparum and the origin and diversification of the Laverania subgenus
    Linda Duval
    Laboratoire de Biologie fonctionnelle des protozoaires, Unité Scientifique du Muséum 504, Museum national d histoire naturelle, 75005 Paris, France
    Proc Natl Acad Sci U S A 107:10561-6. 2010
    ..other chimpanzee samples are different from those in the ape clade: two are Plasmodium ovale, and one is Plasmodium malariae. That is, we have found three human Plasmodium parasites in chimpanzees...
  101. pmc Comparison of PCR and microscopy for the detection of asymptomatic malaria in a Plasmodium falciparum/vivax endemic area in Thailand
    Russell E Coleman
    Departments of Entomology and Immunology, US Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Malar J 5:121. 2006
    ..The main objective of this study was to compare the performance of nested PCR with expert microscopy as a means of detecting Plasmodium parasites during active malaria surveillance in western Thailand...

Research Grants7

  1. IN VITRO CULTIVATION/MALARIA PARASITE PLASMODIUM VIVAX
    H Lanners; Fiscal Year: 1990
    ..Except for P. falciparum, no other human malaria parasite (P. vivax, Plasmodium ovale, Plasmodium malariae) has been continuously cultivated in vitro...
  2. New Role for a Conserved Plasmodium Transcription Factor
    Lawrence W Bergman; Fiscal Year: 2013
    ..Four species of Plasmodium are infectious to humans: Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale and Plasmodium vivax...
  3. Transmucosal Intra-Oral Drug Delivery System for THC
    Mahmoud Elsohly; Fiscal Year: 2003
    ..abstract_text> ..
  4. Compositions for Prevention/Prophylactic Treatment of Poison Ivy Dermatitis
    Mahmoud Elsohly; Fiscal Year: 2006
    ..This proposal addresses a major public health problem, namely contact allergic dermatitis and promises the development of an effective agent to address this problem. [unreadable] [unreadable]..
  5. The effect of mixed Plasmodium infections on morbidity
    Ivo Mueller; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  6. PLASMODIUM VIVAX MSP-3 AND MSP-9 AS VACCINE IMMUNOGENES
    Mary Galinski; Fiscal Year: 2007
    ..vivax vaccine candidates based on these antigens and also serve to establish reliable procedures to test and evaluate antigens in non-human primate models for safety, immunogenicity and efficacy. ..
  7. Molecular Mechanisms of Antigenic Variation in Malaria
    Mary R Galinski; Fiscal Year: 2010
    ....