opisthorchis

Summary

Summary: A genus of trematode liver flukes of the family Opisthorchidae. It consists of the following species: O. felineus, O. noverca (Amphimerus noverca), and O. viverrini. The intermediate hosts are snails, fish, and amphibia.

Top Publications

  1. ncbi Ultrasound screening for Opisthorchis viverrini-associated cholangiocarcinomas: experience in an endemic area
    Eimorn Mairiang
    Department of Radiology, Cancer Unit, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    Asian Pac J Cancer Prev 7:431-3. 2006
  2. pmc Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos
    Banchob Sripa
    Tropical Disease Research Laboratory, Department of Pathology, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 120:S158-68. 2011
  3. pmc Unlocking the transcriptomes of two carcinogenic parasites, Clonorchis sinensis and Opisthorchis viverrini
    Neil D Young
    Department of Veterinary Science, The University of Melbourne, Werribee, Victoria, Australia
    PLoS Negl Trop Dis 4:e719. 2010
  4. ncbi Food-borne trematodiases in Southeast Asia epidemiology, pathology, clinical manifestation and control
    Banchob Sripa
    Tropical Disease Research Laboratory TDR, Department of Pathology, Faculty of Medicine, Khon Kaen University, Thailand
    Adv Parasitol 72:305-50. 2010
  5. pmc The current status of opisthorchiasis and clonorchiasis in the Mekong Basin
    Paiboon Sithithaworn
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:10-6. 2012
  6. pmc The secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke Opisthorchis viverrini
    Jason Mulvenna
    Division of Infectious Diseases, Queensland Institute of Medical Research, QLD, Australia
    Proteomics 10:1063-78. 2010
  7. pmc Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6
    Banchob Sripa
    Department of Pathology, Khon Kaen University School of Medicine, Khon Kaen, Thailand
    Hepatology 50:1273-81. 2009
  8. ncbi Epidemiology of Opisthorchis viverrini in a rural district of southern Lao PDR
    Somphou Sayasone
    Institut de la Francophonie pour la Médecine Tropicale, Vientiane, Lao PDR
    Trans R Soc Trop Med Hyg 101:40-7. 2007
  9. ncbi Taxonomy and biology of liver flukes
    Sasithorn Kaewkes
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 88:177-86. 2003
  10. ncbi Epidemiology of Opisthorchis viverrini
    Paiboon Sithithaworn
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 88:187-94. 2003

Detail Information

Publications206 found, 100 shown here

  1. ncbi Ultrasound screening for Opisthorchis viverrini-associated cholangiocarcinomas: experience in an endemic area
    Eimorn Mairiang
    Department of Radiology, Cancer Unit, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    Asian Pac J Cancer Prev 7:431-3. 2006
    ..In the Northeast region, cholangiocarcinoma (CHCA) is the prevalent type, with Opisthorchis viverrini (OV), an endemic liver fluke, being considered the cause...
  2. pmc Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos
    Banchob Sripa
    Tropical Disease Research Laboratory, Department of Pathology, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 120:S158-68. 2011
    Liver fluke infection caused by Opisthorchis viverrini is a major public health problem in Thailand and the Lao People's Democratic Republic (Lao PDR; Laos)...
  3. pmc Unlocking the transcriptomes of two carcinogenic parasites, Clonorchis sinensis and Opisthorchis viverrini
    Neil D Young
    Department of Veterinary Science, The University of Melbourne, Werribee, Victoria, Australia
    PLoS Negl Trop Dis 4:e719. 2010
    The two parasitic trematodes, Clonorchis sinensis and Opisthorchis viverrini, have a major impact on the health of tens of millions of humans throughout Asia...
  4. ncbi Food-borne trematodiases in Southeast Asia epidemiology, pathology, clinical manifestation and control
    Banchob Sripa
    Tropical Disease Research Laboratory TDR, Department of Pathology, Faculty of Medicine, Khon Kaen University, Thailand
    Adv Parasitol 72:305-50. 2010
    ..We focus particularly on opisthorchiasis caused by Opisthorchis viverrini and clonorchiasis caused by Clonorchis sinensis, which people contract by ingestion of metacercariae ..
  5. pmc The current status of opisthorchiasis and clonorchiasis in the Mekong Basin
    Paiboon Sithithaworn
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:10-6. 2012
    ..review highlights the current status and control of liver fluke infections in the Mekong Basin countries where Opisthorchis and Clonorchis are highly endemic...
  6. pmc The secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke Opisthorchis viverrini
    Jason Mulvenna
    Division of Infectious Diseases, Queensland Institute of Medical Research, QLD, Australia
    Proteomics 10:1063-78. 2010
    Infection with the human liver fluke, Opisthorchis viverrini, is a serious public health problem in Thailand, Laos and nearby locations in Southeast Asia...
  7. pmc Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6
    Banchob Sripa
    Department of Pathology, Khon Kaen University School of Medicine, Khon Kaen, Thailand
    Hepatology 50:1273-81. 2009
    More than 750 million people are at risk of infection with foodborne liver flukes. Opisthorchis viverrini is considered among the most important of these parasites, due to its strong association with cholangiocarcinoma (CCA). O...
  8. ncbi Epidemiology of Opisthorchis viverrini in a rural district of southern Lao PDR
    Somphou Sayasone
    Institut de la Francophonie pour la Médecine Tropicale, Vientiane, Lao PDR
    Trans R Soc Trop Med Hyg 101:40-7. 2007
    In Lao PDR, detailed investigations on Opisthorchis viverrini are scarce. The objective was to document epidemiological features of O. viverrini infections in a highly endemic district...
  9. ncbi Taxonomy and biology of liver flukes
    Sasithorn Kaewkes
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 88:177-86. 2003
    b>Opisthorchis viverrini is a human liver fluke endemic in Thailand, Lao PDR and Cambodia. Three subspecies of Bithynia siamensis and 18 species of cyprinoid fish are susceptible first and second intermediate hosts, respectively...
  10. ncbi Epidemiology of Opisthorchis viverrini
    Paiboon Sithithaworn
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 88:187-94. 2003
    b>Opisthorchis viverrini is a food borne trematode, important because of the sheer numbers of people infected and its serious morbidities such as hepatobiliary diseases and cholangiocarcinoma (CHCA)...
  11. pmc Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini
    Porntip Pinlaor
    Department of Pathology, Khon Kaen University, Khon Kaen, Thailand
    PLoS Negl Trop Dis 3:e398. 2009
    The liver fluke Opisthorchis viverrini is classified as a class I carcinogen due to the association between cholangiocarcinoma and chronic O. viverrini infection...
  12. pmc Opisthorchiasis in Thailand: review and current status
    Natthawut Kaewpitoon
    Research and Diagnostic Center for Parasitic Infectious Diseases, Northeastern Region RCPNER, College of Medicine and Public Health, Ubon Rajathanee University, Warinchamrap district, Ubonratchathai province 34190, Thailand
    World J Gastroenterol 14:2297-302. 2008
    Opisthorchiasis caused by Opisthorchis viverrini (O. viverrini) remains a major public health problem in many parts of Southeast Asia including Thailand, Lao PDR, Vietnam and Cambodia...
  13. ncbi Mechanism of NO-mediated oxidative and nitrative DNA damage in hamsters infected with Opisthorchis viverrini: a model of inflammation-mediated carcinogenesis
    Somchai Pinlaor
    Department of Environmental and Molecular Medicine, Mie University School of Medicine, Mie 514 8507, Japan
    Nitric Oxide 11:175-83. 2004
    Inflammation mediated by infection is an important factor causing carcinogenesis. Opisthorchis viverrini (OV) infection is a risk factor of cholangiocarcinoma (CHCA), probably through chronic inflammation...
  14. pmc Opisthorchis viverrini: an underestimated parasite in world health
    Ross H Andrews
    University of South Australia, GPO Box 2471, Adelaide South Australia, Australia 5001, Australia
    Trends Parasitol 24:497-501. 2008
    Infection with Opisthorchis viverrini and its associated cholangiocarcinoma (CCA) is an underestimated problem in the Mekong region of Southeast Asia, despite the widespread use of praziquantel and health education measures for parasite ..
  15. ncbi The global health burden of infection-associated cancers in the year 2002
    Donald Maxwell Parkin
    Clinical Trials Service Unit and Epidemiological Studies Unit, University of Oxford, Headington, UK
    Int J Cancer 118:3030-44. 2006
    ..The attributable fraction at the specific sites varies from 100% of cervix cancers attributable to the papilloma viruses to a tiny proportion (0.4%) of liver cancers (worldwide) caused by liver flukes...
  16. pmc PCR Diagnosis of Opisthorchis viverrini and Haplorchis taichui Infections in a Lao Community in an area of endemicity and comparison of diagnostic methods for parasitological field surveys
    Leonore Lovis
    Parasitology Laboratory, University Neuchâtel, Neuchatel, Switzerland
    J Clin Microbiol 47:1517-23. 2009
    ..Affected individuals often have mixed infections with the liver fluke Opisthorchis viverrini and minute intestinal flukes such as Haplorchis taichui...
  17. ncbi An epidemiological study on Opisthorchis viverrini infection in Lao villages
    J Kobayashi
    Department of Parasitology, Faculty of Medicine, University of the Ryukyus, Nishihara, Okinawa, Japan
    Southeast Asian J Trop Med Public Health 31:128-32. 2000
    The prevalence of liver fluke, Opisthorchis viverrini, infection in rural and urban communities was studied in Khammouane Province in Lao PDR. The infection was the commonest among the villagers examined, showing the positive rates of 52...
  18. pmc Ultrasonography assessment of hepatobiliary abnormalities in 3359 subjects with Opisthorchis viverrini infection in endemic areas of Thailand
    Eimorn Mairiang
    Department of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:208-11. 2012
    ..All were stool-examined for Opisthorchis viverrini infection by standard quantitative formalin/ethyl acetate concentration technique...
  19. ncbi Potassium permanganate staining for differentiation the surface morphology of Opisthorchis viverrini, Haplorchis taichui and Phaneropsolus bonnei eggs
    K Sukontason
    Department of Parasitology, Faculty of Medicine, Chiang Mai University, Thailand
    Southeast Asian J Trop Med Public Health 30:371-4. 1999
    Potassium permanganate staining method was developed for differentiation Opisthorchis viverrini, Haplorchis taichui and Phaneropsolus bonnei eggs. The surfaces of O. viverrini, H. taichui and P...
  20. pmc A new PCR-based approach indicates the range of Clonorchis sinensis now extends to Central Thailand
    Rebecca J Traub
    School of Veterinary Science, University of Queensland, St Lucia, Queensland, Australia
    PLoS Negl Trop Dis 3:e367. 2009
    ..The lowest quantity of DNA that could be amplified from individual adults of Opisthorchis viverrini, Clonorchis sinensis and Haplorchis taichui was estimated at 0.6 pg, 0.8 pg and 3 pg, respectively...
  21. pmc Spatial distribution of, and risk factors for, Opisthorchis viverrini infection in southern Lao PDR
    Armelle Forrer
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 6:e1481. 2012
    b>Opisthorchis viverrini is a food-borne trematode species that might give rise to biliary diseases and the fatal cholangiocarcinoma. In Lao PDR, an estimated 2.5 million individuals are infected with O...
  22. ncbi Diagnostic values of parasite-specific antibody detections in saliva and urine in comparison with serum in opisthorchiasis
    Prajak Sawangsoda
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Parasitol Int 61:196-202. 2012
    Infection by the liver fluke (Opisthorchis viverrini) causes hepatobiliary disease and bile duct cancer (cholangiocarcinoma, CCA) in endemic areas in Southeast Asia...
  23. ncbi The ELISA-based detection of anti-Opisthorchis viverrini IgG and IgG4 in samples of human urine and serum from an endemic area of north-eastern Thailand
    S Tesana
    Food Borne Parasite Research Group, Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Ann Trop Med Parasitol 101:585-91. 2007
    The levels of correlation between the number of Opisthorchis viverrini eggs excreted in the faeces and levels of anti-Opisthorchis IgG and IgG(4) in the serum and urine (as indicated by absorbances in ELISA) have recently been evaluated ..
  24. ncbi The ecology of the Bithynia first intermediate hosts of Opisthorchis viverrini
    Trevor Petney
    Department of Ecology and Parasitology, Karlsruhe Institute of Technology, Kornblumenstrasse 13, Karlsruhe, Germany
    Parasitol Int 61:38-45. 2012
    ..Here we review the information which is available on the Bithynia hosts of Opisthorchis viverrini. Only one major ecological study has been carried out at one site on a single species of Bithynia...
  25. ncbi Raw attitudes, wetland cultures, life-cycles: socio-cultural dynamics relating to Opisthorchis viverrini in the Mekong Basin
    Carl Grundy-Warr
    Department of Geography, National University of Singapore, 21 Lower Kent Ridge Road, Singapore 119077, Singapore
    Parasitol Int 61:65-70. 2012
    b>Opisthorchis viverrini is one of the most common and medically important food-borne parasites in the Lower Mekong area of Southeast Asia...
  26. ncbi Opisthorchiasis control in Thailand
    P Jongsuksuntigul
    Department of Disease Control, Ministry of Public Health, Tiwanon Road, Nonthaburi 11000, Thailand
    Acta Trop 88:229-32. 2003
    ..The prevalence rate was remarkably high in the North and moderately high in the Northeast, while the prevalence in the Central region was considerably low and there was no evidence of disease transmission in the South...
  27. ncbi Discovery of Opisthorchis viverrini metacercariae in freshwater fish in southern Cambodia
    Sarun Touch
    Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    Acta Trop 111:108-13. 2009
    Small liver flukes, Clonorchis sinensis and Opisthorchis viverini, are fish-borne trematodes (FBTs) causing significant public health problems in Asia. While C. sinensis is distributing mainly in far east Asia, O...
  28. pmc Opisthorchis viverrini: the carcinogenic human liver fluke
    Natthawut Kaewpitoon
    Department of Parasitology, College of Medicine and Public Health, Ubon Rajathanee University, Warin Chamrap District, Ubonratchathani Province 34190, Thailand
    World J Gastroenterol 14:666-74. 2008
    Opisthorchiasis caused by Opisthorchis viverrini remains a major public health problem in many parts of Southeast Asia, including Thailand, Lao PDR, Vietnam and Cambodia...
  29. ncbi Hepatobiliary changes, antibody response, and alteration of liver enzymes in hamsters re-infected with Opisthorchis viverrini
    Somchai Pinlaor
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Exp Parasitol 108:32-9. 2004
    We investigated pathological changes, antibody response, and liver enzymes in hamsters re-infected with Opisthorchis viverrini...
  30. ncbi Clinical manifestation of opisthorchiasis and treatment
    Eimorn Mairiang
    Department of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Acta Trop 88:221-7. 2003
    ..Details of clinical manifestations of opisthorchiasis, hepatobiliary diseases and liver functions, community-based ultrasound study, treatment efficacy, and future study are discussed...
  31. ncbi Genetic and environmental determinants of risk for cholangiocarcinoma via Opisthorchis viverrini in a densely infested area in Nakhon Phanom, northeast Thailand
    Satoshi Honjo
    Epidemiology Unit, Research Institute, Tochigi Cancer Centre, Utsunomiya, Japan
    Int J Cancer 117:854-60. 2005
    Infection with Opisthorchis viverrini (OV) is associated with cholangiocarcinoma. OV is common in northeast Thailand, but less than 10% of the inhabitants develop cholangiocarcinoma...
  32. ncbi Liver fluke-associated cholangiocarcinoma
    P Watanapa
    Departments of Surgery and Physiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10 700, Thailand
    Br J Surg 89:962-70. 2002
    ..Infection with liver flukes has been reported to be associated with bile duct malignancy...
  33. pmc Improvement of PCR for detection of Opisthorchis viverrini DNA in human stool samples
    Kunyarat Duenngai
    Department of Parasitology, Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    J Clin Microbiol 46:366-8. 2008
    b>Opisthorchis viverrini is an important food-borne trematode in Southeast Asia. The infection causes significant morbidity in terms of hepatobiliary diseases and cholangiocarcinoma...
  34. ncbi Acute renal failure in obstructive jaundice in cholangiocarcinoma
    P Mairiang
    Department of Medicine, Khon Kaen Thailand, University
    Arch Intern Med 150:2357-60. 1990
    ..Clinical data highlight the higher serum bilirubin levels and the frequent occurrence of hyponatremia, hypokalemia, and hypotension in renal failure. Their possible roles in contributing to the development of renal failure are discussed...
  35. ncbi Organization of the nervous system in Opisthorchis viverrini investigated by histochemical and immunohistochemical study
    Ratana Leksomboon
    Department of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:107-11. 2012
    ..However, the neuroanatomy of the carcinogenic liver fluke, Opisthorchis viverrini has not been described...
  36. pmc Evaluation of liver fluke recombinant cathepsin B-1 protease as a serodiagnostic antigen for human opisthorchiasis
    Jittiyawadee Sripa
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:191-5. 2012
    ..family C1 is abundantly expressed in the transcriptome and proteome of the carcinogenic liver fluke of humans, Opisthorchis viverrini. This enzyme is present in excretory/secretory (ES) products released by parasites cultured in vitro...
  37. ncbi Copro-DNA diagnosis of Opisthorchis viverrini and Haplorchis taichui infection in an endemic area of Lao PDR
    Megumi Sato
    Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 41:28-35. 2010
    ..PCR targeting ITS1 and ITS2 regions were performed using primer specific for Opisthorchis viverrini, Haplorchis taichui and other related species...
  38. ncbi Secreted Opisthorchis viverrini glutathione S-transferase regulates cell proliferation through AKT and ERK pathways in cholangiocarcinoma
    Daoyot Daorueang
    Graduate School, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:155-61. 2012
    b>Opisthorchis viverrini can develop mitogenic substances into the excretory/secretory product (ESP) that may play an important role in promoting the genesis of cholangiocarcinoma (CCA)...
  39. ncbi Specific serum IgG, but not IgA, antibody against purified Opisthorchis viverrini antigen associated with hepatobiliary disease and cholangiocarcinoma
    Porntip Pinlaor
    Centre for Research and Development in Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:212-6. 2012
    Opisthorchiasis caused by Opisthorchis viverrini infection induces hepatobiliary disease (HBD)-associated cholangiocarcinoma (CCA) via a chronic inflammatory immune response...
  40. ncbi Sequences and gene organization of the mitochondrial genomes of the liver flukes Opisthorchis viverrini and Clonorchis sinensis (Trematoda)
    X Q Cai
    State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, CAAS, Lanzhou, Gansu Province, 730046, People s Republic of China
    Parasitol Res 110:235-43. 2012
    b>Opisthorchis viverrini and Clonorchis sinensis are important trematodes infecting humans and animals, belonging to the family Opisthorchiidae...
  41. pmc Elevated plasma IL-6 associates with increased risk of advanced fibrosis and cholangiocarcinoma in individuals infected by Opisthorchis viverrini
    Banchob Sripa
    Department of Pathology, Khon Kaen University School of Medicine, Khon Kaen, Thailand
    PLoS Negl Trop Dis 6:e1654. 2012
    b>Opisthorchis viverrini is considered among the most important of the food-borne trematodes due to its strong association with advanced periductal fibrosis and bile duct cancer (cholangiocarcinoma)...
  42. ncbi A large outbreak of Opisthorchis felineus in Italy suggests that opisthorchiasis develops as a febrile eosinophilic syndrome with cholestasis rather than a hepatitis-like syndrome
    A Traverso
    Infectious Diseases Unit, U Parini Hospital, Aosta, Italy
    Eur J Clin Microbiol Infect Dis 31:1089-93. 2012
    ..Even if stool test remains the diagnostic gold standard, we found earlier positivity with the serum antibody test. Without previous freezing, the consumption of raw freshwater fish should be avoided...
  43. pmc The tumorigenic liver fluke Opisthorchis viverrini--multiple pathways to cancer
    Banchob Sripa
    Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002 Thailand
    Trends Parasitol 28:395-407. 2012
    Liver fluke infection caused by Opisthorchis viverrini is a major public health problem in Thailand and adjacent countries. In addition to infection-associated morbidity, infection with O...
  44. ncbi High prevalence of Opisthorchis viverrini infection in reservoir hosts in four districts of Khon Kaen Province, an opisthorchiasis endemic area of Thailand
    Surasit Aunpromma
    Department of Veterinary Pathobiology, Faculty of Veterinary Medicine, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:60-4. 2012
    ..Ban Haet, Ban Phai, Chonnabot and Muncha Khiri Districts, Khon Kaen, this study investigated the prevalence of Opisthorchis viverrini infection using a formalin-ether sedimentation method as the gold standard, and hematology and blood ..
  45. ncbi Viable metacercariae of Opisthorchis viverrini in northeastern Thai cyprinid fish dishes--as part of a rational program for control of O. viverrini-associated cholangiocarcinoma
    Jiraporn Prasongwatana
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    Parasitol Res 112:1323-7. 2013
    ..Opisthorchiasis and Opisthorchis viverrini-associated bile duct cancer are prevalent among the residents in northeastern Thailand, who prefer ..
  46. ncbi High excretion of etheno adducts in liver fluke-infected patients: protection by praziquantel against DNA damage
    Somkid Dechakhamphu
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Cancer Epidemiol Biomarkers Prev 17:1658-64. 2008
    Chronic infection by Opisthorchis viverrini (OV) is a strong risk factor for developing cholangiocarcinoma (CCA)...
  47. pmc Genetic variation at three enzyme loci within a Thailand population of Opisthorchis viverrini
    Weerachai Saijuntha
    Walai Rukhavej Botanical Research Institute, Mahasarakham University, Mahasarakham 44150, Thailand
    Parasitol Res 103:1283-7. 2008
    Genetic variation among 231 individuals of Opisthorchis viverrini from the Ban Phai District, Khon Kaen Province (Thailand) was examined at three polymorphic enzymes: enolase (ENOL), phosphoglucomutase (PGM), and triose phosphate ..
  48. ncbi Microsatellite loci in the carcinogenic liver fluke, Opisthorchis viverrini and their application as population genetic markers
    Nonglak Laoprom
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Infect Genet Evol 10:146-53. 2010
    b>Opisthorchis viverrini is a carcinogenic foodborne trematode endemic in Southeast Asia especially in Thailand and the Lao People's Democratic Republic...
  49. ncbi Immunology and molecular biology of Opisthorchis viverrini infection
    S Wongratanacheewin
    Department of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Acta Trop 88:195-207. 2003
    ..IgG levels appear to correlate with gall bladder size and dysfunction and correlated significantly with opisthorchis egg count and decrease after treatment...
  50. pmc Infection with the carcinogenic human liver fluke, Opisthorchis viverrini
    Michael J Smout
    Queensland Tropical Health Alliance, James Cook University, Cairns, QLD, Australia
    Mol Biosyst 7:1367-75. 2011
    ..in people from rural settings in Laos and Northeast Thailand who are infected with the liver fluke, Opisthorchis viverrini, one of only three carcinogenic eukaryotic pathogens...
  51. ncbi Affinity purified oval antigen for diagnosis of Opisthorchiasis viverrini
    T Wongsaroj
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Bangkok, Thailand
    Asian Pac J Allergy Immunol 19:245-58. 2001
    Monoclonal antibodies (MAb) were raised against an oval antigen of the liver fluke Opisthorchis viverrini which is the causative agent of a parasitosis, i.e. opisthorchiasis in Thailand...
  52. ncbi Biological variation within Opisthorchis viverrini sensu lato in Thailand and Lao PDR
    Nonglak Laoprom
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Liver Fluke and Cholangiocarcinoma Research Center, Khon Kaen 40002, Thailand
    J Parasitol 95:1307-13. 2009
    Previous molecular genetic analyses indicate that Opisthorchis viverrini is a complex of at least 2 cryptic species in Thailand and the Lao People's Democratic Republic (PDR). Opisthorchis viverrini sensu lato (s.l...
  53. ncbi The liver fluke Opisthorchis viverrini expresses nitric oxide synthase but not gelatinases
    Suksanti Prakobwong
    Department of Biology, Faculty of Science, Udon Thani Rajabhat University, Udon Thani 41000, Thailand
    Parasitol Int 61:112-7. 2012
    Host-parasite interaction during infection with the liver fluke Opisthorchis viverrini plays an important role in opisthorchiasis-associated cholangiocarcinoma via nitric oxide (NO) production...
  54. ncbi The systematics and population genetics of Opisthorchis viverrini sensu lato: implications in parasite epidemiology and bile duct cancer
    Paiboon Sithithaworn
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 61:32-7. 2012
    Together with host and environmental factors, the systematics and population genetic variation of Opisthorchis viverrini may contribute to recorded local and regional differences in epidemiology and host morbidity in opisthorchiasis and ..
  55. ncbi Opisthorchis felineus, an emerging infection in Italy and its implication for the European Union
    Edoardo Pozio
    European Union Reference Laboratory for Parasites, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Acta Trop 126:54-62. 2013
    The liver fluke Opisthorchis felineus is one of the few zoonotic trematodes that circulates in the European Union (EU)...
  56. pmc RNA interference targeting cathepsin B of the carcinogenic liver fluke, Opisthorchis viverrini
    Jittiyawadee Sripa
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Parasitol Int 60:283-8. 2011
    Functional genomics have not been reported for Opisthorchis viverrini or the related fish-borne fluke, Clonorchis sinensis. Here we describe the introduction by square wave electroporation of Cy3-labeled small RNA into adult O...
  57. pmc Proteomic identification of plasma protein tyrosine phosphatase alpha and fibronectin associated with liver fluke, Opisthorchis viverrini, infection
    Jarinya Khoontawad
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    PLoS ONE 7:e45460. 2012
    Opisthorchiasis caused by Opisthorchis viverrini induces periductal fibrosis via host immune/inflammatory responses...
  58. ncbi Light and electron microscopy observations of embryogenesis and egg development in the human liver fluke, Opisthorchis viverrini (Platyhelminthes, Digenea)
    Panita Khampoosa
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Res 110:799-808. 2012
    ..Those of the human liver flukes, Opisthorchis viverrini, hatch within the gastrointestinal canal of their snail hosts...
  59. ncbi Impact of temporal changes and host factors on the genetic structure of a population of Opisthorchis viverrini sensu lato in Khon Kaen Province (Thailand)
    W Saijuntha
    Walai Rukhavej Botanical Research Institute WRBRI, Mahasarakham University, Mahasarakham 44150, Thailand
    Parasitology 136:1057-63. 2009
    The population genetics of 317 individual Opisthorchis viverrini from Khon Kaen Province Thailand, from 4 different years and 4 cyprinid fish species was examined using multilocus enzyme electrophoresis of enolase (Enol), ..
  60. ncbi Rapid detection of Opisthorchis viverrini and Strongyloides stercoralis in human fecal samples using a duplex real-time PCR and melting curve analysis
    Penchom Janwan
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Res 109:1593-601. 2011
    Human opisthorchiasis caused by the liver fluke Opisthorchis viverrini is an endemic disease in Southeast Asian countries including the Lao People's Democratic Republic, Cambodia, Vietnam, and Thailand...
  61. pmc A follow-up study of Opisthorchis viverrini infection after the implementation of control program in a rural community, central Thailand
    Picha Suwannahitatorn
    Department of Parasitology, Phramongkutklao College of Medicine, 315 Ratchawithi Road, Ratchathewi, Bangkok, Thailand
    Parasit Vectors 6:188. 2013
    b>Opisthorchis viverrini infection is still one of the public health problems in Thailand. Our recent cohort study conducted in a rural community in central Thailand showed that the incidence rate of O...
  62. ncbi Opisthorchis felineus and Metorchis bilis are the main agents of liver fluke infection of humans in Russia
    Viatcheslav A Mordvinov
    Institute of Cytology and Genetics Siberian Branch of RAS, Novosibirsk, Russia
    Parasitol Int 61:25-31. 2012
    ..b>Opisthorchis felineus, the trematode belonging to the family Opisthorchiidae, is a well known causative agent of the ..
  63. pmc Cryptic and asymptomatic Opisthorchis felineus infections
    Orlando Armignacco
    Unita Operativa Complessa Malattie Infettive, Belcolle Hospital, Viterbo, Italy
    Am J Trop Med Hyg 88:364-6. 2013
    ..Serology by enzyme-linked immunosorbent assay and polymerase chain reaction fecal analysis were shown to be the most sensitive diagnostic tools...
  64. pmc Human illnesses caused by Opisthorchis felineus flukes, Italy
    Orlando Armignacco
    Belcolle Hospital, Viterbo, Italy
    Emerg Infect Dis 14:1902-5. 2008
    We report 2 outbreaks of Opisthorchis felineus infection caused by the consumption of tench filets (Tinca tinca) from a lake in Italy. Of the 22 infected persons, 10 (45.4%) were asymptomatic...
  65. ncbi Early stage biliary and intrahepatic migration of Opisthorchis viverrini in the golden hamster
    C Nithikathkul
    Department of Biological Science, Faculty of Science and Technology, Huachiew Chalermprakiet University, Samut Prakan 10540, Thailand
    J Helminthol 81:39-41. 2007
    In Thailand, infection with the liver fluke Opisthorchis viverrini is a serious health problem, with over 8.6 million human infections each year. Early stage biliary intrahepatic migration and infection of O...
  66. ncbi Monophyly of Opisthorchis viverrini populations in the lower Mekong Basin, using mitochondrial DNA nad1 gene as the marker
    Urusa Thaenkham
    Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Parasitol Int 59:242-7. 2010
    The liver fluke, Opisthorchis viverrini, causes serious public-health problems in the Lower Mekong Basin. This study aimed to clarify whether O. viverrini populations may be genetically divided into sub-specific taxa...
  67. ncbi The complete mitochondrial genomes of the liver flukes Opisthorchis felineus and Clonorchis sinensis (Trematoda)
    Sergei V Shekhovtsov
    The Institute of Cytology and Genetics, Novosibirsk, Russian Federation
    Parasitol Int 59:100-3. 2010
    The complete mitochondrial genomes of the parasitic trematodes Opisthorchis felineus and Clonorchis sinensis (family Opisthorchiidae) were fully sequenced in order to develop markers for DNA diagnostics of the liver flukes infection, ..
  68. ncbi Genetic comparison of liver flukes, Clonorchis sinensis and Opisthorchis viverrini, based on rDNA and mtDNA gene sequences
    Gab Man Park
    Department of Parasitology, Kwandong University College of Medicine, Gangneung, Kangweon Do, South Korea
    Parasitol Res 100:351-7. 2007
    To clarify the genetic relationships between Clonorchis sinensis and Opisthorchis viverrini, patterns of inter-/intraspecific polymorphism were compared for four markers with nuclear ribosomal DNA (rDNA) and mitochondrial DNA (mtDNA) in ..
  69. ncbi Opisthorchis viverrini: the effects of colchicine and cytochalasin B on the adult tegument
    P Sobhon
    Department of Anatomy, Faculty of Science, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 27:312-8. 1996
    ....
  70. ncbi Opisthorchis viverrini antigen induces the expression of Toll-like receptor 2 in macrophage RAW cell line
    Somchai Pinlaor
    Department of Parasitology, Khon Kaen University, Thailand
    Int J Parasitol 35:591-6. 2005
    b>Opisthorchis viverrini infection induces inflammation in and around the bile duct, leading to cholangiocarcinoma in humans. To examine the mechanism of O...
  71. ncbi Time profiles of the expression of metalloproteinases, tissue inhibitors of metalloproteases, cytokines and collagens in hamsters infected with Opisthorchis viverrini with special reference to peribiliary fibrosis and liver injury
    Suksanti Prakobwong
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Int J Parasitol 39:825-35. 2009
    The liver fluke Opisthorchis viverrini is endemic in southeastern Asia, and causes cholangiocarcinoma and liver fibrosis...
  72. ncbi Opisthorchis viverrini and opisthorchiasis: the 21st century review
    B Sripa
    Acta Trop 88:169-70. 2003
  73. pmc Secreted cysteine proteases of the carcinogenic liver fluke, Opisthorchis viverrini: regulation of cathepsin F activation by autocatalysis and trans-processing by cathepsin B
    Jittiyawadee Sripa
    Department of Parasitology, Khon Kaen University, Thailand
    Cell Microbiol 12:781-95. 2010
    b>Opisthorchis viverrini is an important helminth pathogen of humans that is endemic in Thailand and Laos. Adult flukes reside within host bile ducts and feed on epithelial tissue and blood cells...
  74. ncbi Proteomic identification of peroxiredoxin 6 for host defence against Opisthorchis viverrini infection
    J Khoontawad
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasite Immunol 32:314-23. 2010
    b>Opisthorchis viverrini infection causes opisthorchiasis and is a risk factor for cholangiocarcinoma via chronic inflammation. To investigate the mechanism of O...
  75. ncbi Discrimination of O. viverrini, C. sinensis, H. pumilio and H. taichui using nuclear DNA-based PCR targeting ribosomal DNA ITS regions
    Megumi Sato
    Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, 420 6 Ratchawithi Road, Ratchathewi, Bangkok 10400, Thailand
    Acta Trop 109:81-3. 2009
    ..The PCR amplicons of Opisthorchis viverrini, Clonorchis sinensis, Haplorchis pumilio, and Haplorchis taichui were 800, 820, 1250, and 930 bp for ..
  76. ncbi Curcumin reduces oxidative and nitrative DNA damage through balancing of oxidant-antioxidant status in hamsters infected with Opisthorchis viverrini
    Somchai Pinlaor
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Mol Nutr Food Res 53:1316-28. 2009
    b>Opisthorchis viverrini (OV) infection is endemic in northeastern Thailand...
  77. pmc Opisthorchis viverrini excretory/secretory products induce toll-like receptor 4 upregulation and production of interleukin 6 and 8 in cholangiocyte
    Kantima Ninlawan
    Graduate School, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitol Int 59:616-21. 2010
    Biliary tract infection with the Group I carcinogenic liver fluke Opisthorchis viverrini is associated with severe inflammation leading to cholangiocarcinoma--a major biliary cancer in Southeast Asia...
  78. ncbi Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, tribendimidine, and praziquantel in patients with Opisthorchis viverrini: a randomised, exploratory, open-label, phase 2 trial
    Phonepasong Soukhathammavong
    National Institute of Public Health, Ministry of Health, Vientiane, Laos
    Lancet Infect Dis 11:110-8. 2011
    Praziquantel is the only drug available for treatment of Opisthorchis viverrini, although in-vivo studies point to activity of mefloquine, artesunate, and tribendimidine against this liver fluke...
  79. ncbi Development and evaluation of a polymerase chain reaction (PCR) assay for the detection of Opisthorchis viverrini in fish
    Ammini Parvathi
    Department of Fishery Microbiology, Karnataka Veterinary, Animal and Fisheries Sciences University, College of Fisheries, Mangalore 575 002, India
    Acta Trop 107:13-6. 2008
    Human opisthorchiais caused by the liver fluke Opisthorchis viverrini is a major fish-borne trematode infection endemic in the Southeast Asian countries...
  80. pmc Inflammatory response to liver fluke Opisthorchis viverrini in mice depends on host master coregulator MTA1, a marker for parasite-induced cholangiocarcinoma in humans
    Sujit S Nair
    Department of Biochemistry and Molecular Biology, George Washington University, Washington, DC 20016, USA
    Hepatology 54:1388-97. 2011
    ..in oncogenesis and inflammation, we explored the links between parasitism by the carcinogenic liver fluke Opisthorchis viverrini and this coregulator using both an Mta1(-/-) mouse model of infection and a tissue microarray of ..
  81. ncbi Molecular identification and phylogenetic analysis of nuclear rDNA sequences among three opisthorchid liver fluke species (Opisthorchiidae: Trematoda)
    Seokha Kang
    Department of Parasitology and Medical Research Institute, College of Medicine, Chungbuk National University, Cheongju, Chungbuk 361 763, Republic of Korea
    Parasitol Int 57:191-7. 2008
    ..development of a fast and accurate molecular identification system for human-associated liver fluke species (Opisthorchis viverrini, Opisthorchis felineus, and Clonorchis sinensis) using the PCR-RFLP analysis of the 18S-ITS1-5...
  82. ncbi Opisthorchis viverrini: efficacy and tegumental alterations following administration of tribendimidine in vivo and in vitro
    Jennifer Keiser
    Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, P O Box, CH 4002 Basel, Switzerland
    Parasitol Res 102:771-6. 2008
    The tegumental changes in adult Opisthorchis viverrini induced by tribendimidine were analyzed by scanning electron microscopy (SEM). We exposed O. viverrini to tribendimidine at a concentration of 10 microg/ml for 4 h...
  83. ncbi Biliary liver flukes (Opisthorchiasis and Clonorchiasis) in immigrants in the United States: often subtle and diagnosed years after arrival
    William M Stauffer
    Pediatric and Medicine Faculty, Regions Hospital Healthpartners, Center for International Health and International Travel Clinic, 640 Jackson Street, St Paul, MN 55101, USA
    J Travel Med 11:157-9. 2004
    ..Clonorchis sinensis and Opisthorchis spp. are the major biliary liver flukes associated with human disease...
  84. ncbi Repeated infection with Opisthorchis viverrini induces accumulation of 8-nitroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanine in the bile duct of hamsters via inducible nitric oxide synthase
    Somchai Pinlaor
    Department of Environmental and Molecular Medicine and Department of Anatomy, Mie University School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Carcinogenesis 25:1535-42. 2004
    Chronic inflammation induced by repeated infection with Opisthorchis viverrini has been postulated to be a risk factor for cholangiocarcinoma. To clarify the mechanism of carcinogenesis induced by repeated O...
  85. ncbi Incidence and risk factors of Opisthorchis viverrini infections in a rural community in Thailand
    Ram Rangsin
    Department of Military and Community Medicine, and Department of Parasitology, Phramongkutklao College of Medicine, Bangkok, Thailand
    Am J Trop Med Hyg 81:152-5. 2009
    b>Opisthorchis viverrini infection is one of the major public health problems in Thailand...
  86. pmc Characterization of the antioxidant enzyme, thioredoxin peroxidase, from the carcinogenic human liver fluke, Opisthorchis viverrini
    Sutas Suttiprapa
    Graduate School, Khon Kaen University, 123 Mitraparp Road, Khon Kaen, Thailand
    Mol Biochem Parasitol 160:116-22. 2008
    The human liver fluke, Opisthorchis viverrini, induces inflammation of the hepatobiliary system. Despite being constantly exposed to inimical oxygen radicals released from inflammatory cells, the parasite survives for many years...
  87. ncbi Enzyme markers to identify and characterize Opisthorchis viverrini in Thailand and Lao PDR
    Weerachai Saijuntha
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Southeast Asian J Trop Med Public Health 37:43-7. 2006
    We conducted an allozyme electrophoretic study to explore potential enzyme markers to distinguish Opisthorchis viverrini in Thailand and Lao PDR. Twenty-eight enzymes encoding presumptive 32 loci were established...
  88. pmc Asparaginyl endopeptidase from the carcinogenic liver fluke, Opisthorchis viverrini, and its potential for serodiagnosis
    Thewarach Laha
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Int J Infect Dis 12:e49-59. 2008
    To isolate and characterize an asparaginyl endopeptidase from the carcinogenic liver fluke, Opisthorchis viverrini, and evaluate its expression profile, biochemical activity, and potential as an immunodiagnostic antigen.
  89. ncbi Opisthorchis viverrini and opisthorchiasis: a historical review and future perspective
    E S Upatham
    Department of Medical Science, Faculty of Science, Burapha University, Bangsaen, Chonburi 20131, Thailand
    Acta Trop 88:171-6. 2003
    Opisthorchiasis is caused by the liver fluke, Opisthorchis viverrini. The fluke afflicts approximately seven million inhabitants in northeastern and northern Thailand...
  90. ncbi Oxidative and nitrative stress in Opisthorchis viverrini-infected hamsters: an indirect effect after praziquantel treatment
    Somchai Pinlaor
    Department of Parasitology, and Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Am J Trop Med Hyg 78:564-73. 2008
    ..To examine the mechanism of these effects, we studied the distribution of Opisthorchis viverrini antigens and the expression of inducible nitric oxide synthase (iNOS), nuclear factor-kappaB (NF-..
  91. pmc Gene discovery for the carcinogenic human liver fluke, Opisthorchis viverrini
    Thewarach Laha
    Department of Parasitology, Khon Kaen University, Khon Kaen, Thailand
    BMC Genomics 8:189. 2007
    Cholangiocarcinoma (CCA)--cancer of the bile ducts--is associated with chronic infection with the liver fluke, Opisthorchis viverrini...
  92. ncbi Prevalence of Opisthorchis viverrini infection and incidence of cholangiocarcinoma in Khon Kaen, Northeast Thailand
    S Sriamporn
    Department of Epidemiology, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand
    Trop Med Int Health 9:588-94. 2004
    ..b>Opisthorchis viverrini (OV), a liver fluke, is endemic in the area, and has been evaluated as a cause of CHCA by ..
  93. ncbi Relationship between intensity of Opisthorchis viverrini infection and hepatobiliary disease detected by ultrasonography
    E Mairiang
    Nongrua District Hospital, Khon Kaen Province, Thailand
    J Gastroenterol Hepatol 7:17-21. 1992
    Twenty-four locality-, age- and sex-matched groups of village residents with no light, moderate and heavy Opisthorchis viverrini infection were examined by ultrasonography...
  94. pmc Ov-APR-1, an aspartic protease from the carcinogenic liver fluke, Opisthorchis viverrini: functional expression, immunolocalization and subsite specificity
    Sutas Suttiprapa
    Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Int J Biochem Cell Biol 41:1148-56. 2009
    The human liver fluke Opisthorchis viverrini is endemic in Thailand, Laos and Cambodia where long standing infection is associated with cancer of the bile ducts, cholangiocarcinoma...
  95. pmc Mitochondrial DNA sequence variation among geographical isolates of Opisthorchis viverrini in Thailand and Lao PDR, and phylogenetic relationships with other trematodes
    W Saijuntha
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Parasitology 135:1479-86. 2008
    The present study compared the genetic variation among 14 different geographical isolates of Opisthorchis viverrini sensu lato from Thailand and Lao PDR using sequence data for 2 mitochondrial DNA genes, the subunit 1 of NADH ..
  96. ncbi A case of Opisthorchis felineus infestation in a pilot from Greece
    E Tselepatiotis
    Dept of Internal Medicine, Patission General Hospital, Athens, Greece
    Infection 31:430-2. 2003
    ..Medical personnel should be cognizant of this parasitic infection, since world travel can spread it to areas of the world unaccustomed to it...
  97. ncbi Characterization of cysteine proteases from the carcinogenic liver fluke, Opisthorchis viverrini
    Natthawut Kaewpitoon
    Graduate School, Khon Kaen University, Khon Kaen, Thailand
    Parasitol Res 102:757-64. 2008
    Protease activities in extracts of Opisthorchis viverrini were investigated using gelatin zymography and fluorogenic peptide substrates. Using gelatin-impregnated X-ray film, 2 microg of O...
  98. pmc Evidence of a species complex within the food-borne trematode Opisthorchis viverrini and possible co-evolution with their first intermediate hosts
    Weerachai Saijuntha
    Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Int J Parasitol 37:695-703. 2007
    The food-borne trematodes, Opisthorchis viverrini, O. felineus and Clonorchis sinensis, have long been recognized as the cause of major human health problems, with an estimated 40 million infected persons...
  99. ncbi Prevalence of Opisthorchis viverrini infection among villagers harboring Opisthorchis-like eggs
    K L Sukontason
    Department of Parasitology, Faculty of Medicine, Chiang Mai University, Thailand
    Southeast Asian J Trop Med Public Health 32:23-6. 2001
    The precise occurrence of Opisthochis viverrini infection in humans, who were positive for Opisthorchis-like eggs in a stool examination, was determined using the potassium permanganate staining method...
  100. ncbi Evaluation of PCR based coprodiagnosis of human opisthorchiasis
    C R Stensvold
    Danish Bilharziasis Laboratory DBL, Institute for Health Research and Development, Jaergersborg Allé 1D, DK 2920 Charlottenlund, Denmark
    Acta Trop 97:26-30. 2006
    In this study, a recently developed PCR test for the detection of Opisthorchis viverrini in human faecal samples was evaluated using two parasitological methods as references...
  101. ncbi Gall bladder and extrahepatic bile duct changes in Opisthorchis viverrini-infected hamsters
    Banchob Sripa
    Department of Pathology, Division of Experimental Pathology, Faculty of Medicine, Khon Kaen University, 40002, Khon Kaen, Thailand
    Acta Trop 83:29-36. 2002
    b>Opisthorchis viverrini infection is associated with several hepatobiliary diseases, but few reports have described extrahepatic lesions in opisthorchiasis...

Research Grants7

  1. Role of liver fluke granulin in cholangiocarcinogenesis
    Jason P Mulvenna; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Infection with the food-borne liver fluke parasites Opisthorchis viverrini and Clonorchis sinensis is a strong risk factor for cholangiocarcinoma (CCA), bile duct cancer, in Thailand, Laos and other ..
  2. Pathogenesis, Carcinogenesis and Ecology of Opisthorchiasis in Thailand
    Banchob Sripa; Fiscal Year: 2013
    ..the neglected tropical disease, opisthorchiasis, caused by infection with the fish-borne trematode parasite, Opisthorchis viverrini. Chronic opisthorchiasis often culminates cholangiocarcinoma, cancer of the bile ducts...
  3. Biomarkers of Opisthorchis viverrini-induced cholangiocarcinoma
    Paul J Brindley; Fiscal Year: 2013
    ..risk factor for intrahepatic CCA in Thailand has long been established - infection with the liver fluke Opisthorchis viverrini (OV)...
  4. Pathogenesis of Liver Fluke Induced Cancer in Thailand
    Paul Brindley; Fiscal Year: 2009
    ..between cholangiocarcinoma (CCA)-hepatic cancer of the bile duct epithelia-and infection with the liver fluke, Opisthorchis viverrini. O. viverrini is carcinogenic...
  5. MODULATION OF LIVER FLUKE-ASSOCIATED NEOPLASIA
    Nobuyuki Ito; Fiscal Year: 1990
    ..the disease in man has already been established utilizing the susceptibility of Syrian golden hamsters to Opisthorchis viverrini and chemical carcinogens...
  6. U.T. SOUTHWESTERN ADULT AIDS CLINICAL TRIALS UNIT
    Mamta Jain; Fiscal Year: 2008
    ..abstract_text> ..
  7. Risk Factors for HIV-1 infection Among Young Thai Men
    Ram Rangsin; Fiscal Year: 2009
    ..We propose a case control study of HIV-1 infected young men and their 1:4 controls matched on year of birth, district of residence, and type of conscription. ..