platyhelminths

Summary

Summary: A phylum of acoelomate, bilaterally symmetrical flatworms, without a definite anus. It includes three classes: Cestoda, Turbellaria, and Trematoda.

Top Publications

  1. pmc Free-living flatworms under the knife: past and present
    Bernhard Egger
    Ultrastructural Research and Evolutionary Biology, University of Innsbruck, Innsbruck, Austria
    Dev Genes Evol 217:89-104. 2007
  2. pmc A common origin of complex life cycles in parasitic flatworms: evidence from the complete mitochondrial genome of Microcotyle sebastis (Monogenea: Platyhelminthes)
    Joong Ki Park
    Department of Parasitology, College of Medicine, Chungbuk National University, Cheongju, Chungbuk 361 763, Republic of Korea
    BMC Evol Biol 7:11. 2007
  3. ncbi Mitochondrial genomes of parasitic flatworms
    Thanh H Le
    Molecular Parasitology Laboratory, Australian Centre for International and Tropical Health and Nutrition, The Queensland Institute of Medical Research and The University of Queensland, Brisbane, Queensland 4029, Australia
    Trends Parasitol 18:206-13. 2002
  4. ncbi Comparative analysis of known miRNAs across platyhelminths
    Xiaoliang Jin
    Department of Ophthalmology of Shanghai Tenth People s Hospital and Tongji Eye Institute, Tongji University School of Medicine, Shanghai, China
    FEBS J 280:3944-51. 2013
  5. pmc The alkaloid Ageladine A, originally isolated from marine sponges, used for pH-sensitive imaging of transparent marine animals
    Ulf Bickmeyer
    Alfred Wegener Institute for Polar and Marine Research in the Helmholtz Society, Am Handelshafen 12, 27570 Bremerhaven, Germany
    Mar Drugs 10:223-33. 2012
  6. ncbi Initial steps of speciation by geographic isolation and host switch in salmonid pathogen Gyrodactylus salaris (Monogenea: Gyrodactylidae)
    Maria Meinilä
    Department of Biology, University of Oulu, FIN 90014 Oulu, Finland
    Int J Parasitol 34:515-26. 2004
  7. pmc Acoel development supports a simple planula-like urbilaterian
    Andreas Hejnol
    Kewalo Marine Laboratory, Pacific Bioscience Research Center, University of Hawaii, Honolulu, HI 96813, USA
    Philos Trans R Soc Lond B Biol Sci 363:1493-501. 2008
  8. ncbi Epigenetics: a key regulator of platyhelminth developmental biology?
    Kathrin K Geyer
    Institute of Biological, Environmental and Rural Sciences IBERS, Edward Llwyd Building, Aberystwyth University, Aberystwyth, UK
    Int J Parasitol 42:221-4. 2012
  9. ncbi Qualitative analysis of the risk of introducing Gyrodactylus salaris into the United Kingdom
    E J Peeler
    Centre for Environment, Fisheries and Aquaculture Science, The Nothe, Weymouth DT4 8UB, UK
    Dis Aquat Organ 62:103-13. 2004
  10. ncbi Remarks on the phylogeny and structure of fatty acid binding proteins from parasitic platyhelminths
    A Esteves
    Seccion Bioquimica, Facultad de Ciencias, Universidad de la Republica, Montevideo, Uruguay
    Int J Parasitol 27:1013-23. 1997

Detail Information

Publications221 found, 100 shown here

  1. pmc Free-living flatworms under the knife: past and present
    Bernhard Egger
    Ultrastructural Research and Evolutionary Biology, University of Innsbruck, Innsbruck, Austria
    Dev Genes Evol 217:89-104. 2007
    ..The role of the nervous system and especially the brain for regeneration is discussed, and similarities as well as particularities in regeneration among free-living flatworms are pointed out...
  2. pmc A common origin of complex life cycles in parasitic flatworms: evidence from the complete mitochondrial genome of Microcotyle sebastis (Monogenea: Platyhelminthes)
    Joong Ki Park
    Department of Parasitology, College of Medicine, Chungbuk National University, Cheongju, Chungbuk 361 763, Republic of Korea
    BMC Evol Biol 7:11. 2007
    ....
  3. ncbi Mitochondrial genomes of parasitic flatworms
    Thanh H Le
    Molecular Parasitology Laboratory, Australian Centre for International and Tropical Health and Nutrition, The Queensland Institute of Medical Research and The University of Queensland, Brisbane, Queensland 4029, Australia
    Trends Parasitol 18:206-13. 2002
    ..Among Schistosoma spp., the long non-coding regions are rich in repeats and length variation among individuals is known. Data from mitochondrial genomes are valuable for studies on species identification, phylogenies and biogeography...
  4. ncbi Comparative analysis of known miRNAs across platyhelminths
    Xiaoliang Jin
    Department of Ophthalmology of Shanghai Tenth People s Hospital and Tongji Eye Institute, Tongji University School of Medicine, Shanghai, China
    FEBS J 280:3944-51. 2013
    ..In an attempt to explore the phylogeny of miRNAs across five platyhelminths, we integrated annotated miRNAs and their full genomes...
  5. pmc The alkaloid Ageladine A, originally isolated from marine sponges, used for pH-sensitive imaging of transparent marine animals
    Ulf Bickmeyer
    Alfred Wegener Institute for Polar and Marine Research in the Helmholtz Society, Am Handelshafen 12, 27570 Bremerhaven, Germany
    Mar Drugs 10:223-33. 2012
    ..5), Metridium senile harbours aggregates of high acidity in the tentacles (pH 5) and in Macrostomum lignano, the rhabdoids, the gonads and areas close to the mouth were the most acidic with values down to pH 5...
  6. ncbi Initial steps of speciation by geographic isolation and host switch in salmonid pathogen Gyrodactylus salaris (Monogenea: Gyrodactylidae)
    Maria Meinilä
    Department of Biology, University of Oulu, FIN 90014 Oulu, Finland
    Int J Parasitol 34:515-26. 2004
    ..7-20.3% per million years for COI coding mtDNA. The results supported the hypothesis that parallel to the allopatric mode, host switch and instant isolation by host specificity can be operated as a speciation mechanism...
  7. pmc Acoel development supports a simple planula-like urbilaterian
    Andreas Hejnol
    Kewalo Marine Laboratory, Pacific Bioscience Research Center, University of Hawaii, Honolulu, HI 96813, USA
    Philos Trans R Soc Lond B Biol Sci 363:1493-501. 2008
    ..We also identify the developmental changes related to gastrulation that gave rise to the urbilaterian from a simpler cnidarian-like ancestor...
  8. ncbi Epigenetics: a key regulator of platyhelminth developmental biology?
    Kathrin K Geyer
    Institute of Biological, Environmental and Rural Sciences IBERS, Edward Llwyd Building, Aberystwyth University, Aberystwyth, UK
    Int J Parasitol 42:221-4. 2012
    ..or as causative agents of aquacultural, veterinary and biomedically-relevant parasitic diseases, the platyhelminths are subject to intensive inter-disciplinary research...
  9. ncbi Qualitative analysis of the risk of introducing Gyrodactylus salaris into the United Kingdom
    E J Peeler
    Centre for Environment, Fisheries and Aquaculture Science, The Nothe, Weymouth DT4 8UB, UK
    Dis Aquat Organ 62:103-13. 2004
    ..salaris and economic drivers for live salmonid imports may strengthen. Under these circumstances, legal or illegal live salmonid imports would become the most significant risk of introduction...
  10. ncbi Remarks on the phylogeny and structure of fatty acid binding proteins from parasitic platyhelminths
    A Esteves
    Seccion Bioquimica, Facultad de Ciencias, Universidad de la Republica, Montevideo, Uruguay
    Int J Parasitol 27:1013-23. 1997
    Four fatty acid binding proteins (FABPs) have been described in 4 parasitic platyhelminths: Schistosoma mansoni, Schistosoma japonicum, Fasciola hepatica and Echinococcus granulosus...
  11. ncbi The complete mitochondrial DNA sequence of the monogenean Gyrodactylus thymalli (Platyhelminthes: Monogenea), a parasite of grayling (Thymallus thymallus)
    Laetitia Plaisance
    The Natural History Museum, Department of Zoology, University of Oslo, P O Box 1172, Blindern, NO 0318 Oslo, Norway
    Mol Biochem Parasitol 154:190-4. 2007
    ..Compared to the recently described mt DNA of the closely related G. salaris from Atlantic salmon from Signaldalselva, Norway, the mitochondrial genome of G. thymalli from Hnilec, Slovakia, differs on average by 2.2%...
  12. ncbi The mitochondrial genome of Gyrodactylus salaris (Platyhelminthes: Monogenea), a pathogen of Atlantic salmon (Salmo salar)
    T Huyse
    Parasitic Worms Group, Department of Zoology, The Natural History Museum, London SW7 5BD, UK
    Parasitology 134:739-47. 2007
    ..The completion of the mt genome offers the opportunity of defining new molecular markers for studying evolutionary relationships within and among gyrodactylid species...
  13. ncbi Ancyrocephalidae (Monogenea) of Lake Tanganyika: II: description of the first Cichlidogyrus spp. parasites from Tropheini fish hosts (Teleostei, Cichlidae)
    Céline Gillardin
    Laboratory of Animal Diversity and Systematics, Biology Department, Katholieke Universiteit Leuven, Charles Deberiotstraat 32, 3000, Leuven, Belgium
    Parasitol Res 110:305-13. 2012
    ....
  14. ncbi Choice matters: incipient speciation in Gyrodactylus corydori (Monogenoidea: Gyrodactylidae)
    Marlus Bueno-Silva
    Laboratório de Ecologia Molecular e Parasitologia Evolutiva, Universidade Federal do Parana, Departamento de Zoologia, Curitiba, PR, Brazil
    Int J Parasitol 41:657-67. 2011
    ..ehrhardti and C. paleatus. This may be a common event within the Gyrodactylidae, adding a yet unreported mode of adaptive speciation that helps to understand its rate of diversification...
  15. ncbi Molecular phylogeny of congeneric monogenean parasites (Dactylogyrus): a case of intrahost speciation
    Andrea Simkova
    Department of Zoology and Ecology, Faculty of Science, Masaryk University, Kotlarska 2, 61137 Brno, Czech Republic
    Evolution 58:1001-18. 2004
    ..Moreover, the present study shows that the congeneric parasites speciating within one host tend to occupy niches within hosts differing at least in one niche parameter...
  16. ncbi Hybrid origin of Baltic salmon-specific parasite Gyrodactylus salaris: a model for speciation by host switch for hemiclonal organisms
    Jussi Kuusela
    National Veterinary and Food Research Institute, Oulu Regional Unit, POB 517, FIN 90101 Oulu, Finland
    Mol Ecol 16:5234-45. 2007
    ..Strains having a separate divergent mtDNA observed on farmed rainbow trout, and on salmon in Russian lake Kuito were suggested to be clones derived from secondary and tertiary recombination events...
  17. ncbi Population growth of Gyrodactylus salaris (Monogenea) on Norwegian and Baltic Atlantic salmon (Salmo salar) stocks
    J Cable
    School of Biological Sciences, University of Bristol, UK
    Parasitology 121:621-9. 2000
    ..salaris infects different salmonid hosts...
  18. ncbi The physiological response of the marine platyhelminth Macrostomum lignano to different environmental oxygen concentrations
    G A Rivera-Ingraham
    Department of Functional Ecology, Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research, Am Handelshafen 12, 27570 Bremerhaven, Germany
    J Exp Biol 216:2741-51. 2013
    ....
  19. ncbi Phylogenetic analysis of the Argonaute protein family in platyhelminths
    Yadong Zheng
    State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Lanzhou, Gansu, China
    Mol Phylogenet Evol 66:1050-4. 2013
    ..b>Platyhelminths have been reported to express microRNAs but the diversity of AGOs in the phylum has not been explored...
  20. ncbi Experimental infections of the monogenean Gyrodactylus turnbulli indicate that it is not a strict specialist
    T A King
    School of Biosciences, Cardiff University, Cardiff CF10 3TL, UK
    Int J Parasitol 37:663-72. 2007
    ..In view of the potential importance of host switching under artificial conditions, we propose to describe this as 'artificial ecological transfer' as opposed to 'natural ecological transfer', host switching under natural conditions...
  21. pmc Codon usage and bias in mitochondrial genomes of parasitic platyhelminthes
    Thanh Hoa Le
    Molecular Parasitology Laboratory, Australian Centre for International and Tropical Health and Nutrition, The Queensland Institute of Medical Research and The University of Queensland, Brisbane, Queensland, Australia
    Korean J Parasitol 42:159-67. 2004
    ..A pattern is thus emerging of diversity in the mt genome in neodermatans that may cast light on evolution of mt genomes generally...
  22. pmc Ecological functions of tetrodotoxin in a deadly polyclad flatworm
    Raphael Ritson-Williams
    Smithsonian Marine Station at Fort Pierce, Fort Pierce, FL 34949, USA
    Proc Natl Acad Sci U S A 103:3176-9. 2006
    ..TTX is known to have multiple ecological functions, which has probably led to its widespread presence among prokaryotes and at least 10 metazoan phyla...
  23. ncbi Evolution of body-wall musculature in the Platyhelminthes (Acoelomorpha, Catenulida, Rhabditophora)
    M D Hooge
    Department of Biological Sciences, University of Maine, Orono, Maine 04469 5751, USA
    J Morphol 249:171-94. 2001
    ....
  24. ncbi Comparative susceptibility of two races of Salmo salar (Baltic Lule river and Atlantic Conon river strains) to infection with Gyrodactylus salaris
    M B Dalgaard
    Department of Veterinary Microbiology, Section of Fish Diseases, Royal Veterinary and Agricultural University, 4 Stigbøjlen, 1870 Frederiksberg Centrum, Denmark
    Dis Aquat Organ 53:173-6. 2003
    ..Although the Lule salmon seems more susceptible to infection compared to previous reports on the Neva salmon, the results support the notion that Baltic salmon strains are generally more resistant than East Atlantic salmon...
  25. ncbi The mitochondrial genome of Gyrodactylus derjavinoides (Platyhelminthes: Monogenea)--a mitogenomic approach for Gyrodactylus species and strain identification
    Tine Huyse
    Laboratory of Animal Diversity and Systematics, Catholic University of Leuven, Ch Deberiotstraat 32, B3000 Leuven, Belgium
    Gene 417:27-34. 2008
    ....
  26. ncbi Precocious (pre-anaphase) cleavage furrows in Mesostoma spermatocytes
    Arthur Forer
    Biology Department, York University, 4700 Keele Street, North York, Ontario, Canada M3J 1P3
    Eur J Cell Biol 89:607-18. 2010
    ..Furrow positioning thus is sensitive to the positioning of chromosomes in the spindle and furrow positions change in the absence of spindle microtubules...
  27. ncbi Two new species of Cichlidogyrus Paperna, 1960 (Monogenea, ancyrocephalidae) gill parasites on Hemichromis fasciatus (Pisces, Cichlidae) in Africa, with remarks on parasite geographical distribution
    A Pariselle
    IRD ex ORSTOM GAMET, BP 5095, 34033 Montpellier 1, France
    Parasite 11:359-64. 2004
    ..sanseoi n. sp. and C. teugelsi n. sp. As parasitic species are not present in all the host distribution area, we think that H. fasciatus is made up of two distinct populations (or even sister species)...
  28. ncbi Sporadic sexual reproduction: sex to some degree
    L W Beukeboom
    Heredity (Edinb) 98:123-4. 2007
  29. ncbi Escape from an evolutionary dead end: a triploid clone of Gyrodactylus salaris is able to revert to sex and switch host (Platyhelminthes, Monogenea, Gyrodactylidae)
    Marek S Zietara
    Gdańsk University Biological Station, Laboratory of Comparative Biochemistry, Gdańsk Sobieszewo, Poland
    Hereditas 143:84-90. 2006
    ..Liberalism in ploidy level may significantly add to the evolutionary options available for a parasite in ever-changing environments...
  30. ncbi Phylogeographical pattern of Mazocraeoides gonialosae (Monogenea, Mazocraeidae) on the dotted gizzard shad, Konosirus punctatus, along the coast of China
    Min Li
    State Key Laboratory of Biocontrol and Center for Parasitic Organisms, School of Life Sciences, Sun Yat Sen University, Guangzhou 510275, China
    Int J Parasitol 41:1263-72. 2011
    ..The limited time to accumulate genetic variation after the last glacial maximum may also account in part for the lack of phylogeographical structure in the studied region...
  31. ncbi Organisation of the nervous system in the Acoela: an immunocytochemical study
    M Reuter
    Department of Biology, Abo Akademi University, Finland
    Tissue Cell 33:119-28. 2001
    ..As no synapomorphies were found in the organisation of the nervous system of the Acoela and that of the Platyhelminthes, the results support the view that the Acoela is not a member of the Platyhelminthes...
  32. ncbi The embryonic development of the temnocephalid flatworms Craspedella pedum and Diceratocephala boschmai
    A Younossi-Hartenstein
    Department of Molecular Cell and Developmental Biology, University of California Los Angeles, 90095, USA
    Cell Tissue Res 304:295-310. 2001
    ..Comparison of morphogenesis in temnocephalids with observations in other flatworm taxa suggests a phylotypic stage for this phylum of invertebrates...
  33. ncbi The evolution of monogenean diversity
    Robert Poulin
    Department of Zoology, University of Otago, P O Box 56, Dunedin, New Zealand
    Int J Parasitol 32:245-54. 2002
    ..The phylogenetic analytical framework adopted here should allow these questions to be tackled once the necessary data become available...
  34. ncbi The origins of parasitism in the platyhelminthes: a summary interpreted on the basis of recent literature
    K Rohde
    Department of Zoology, University of New England, Armidale, N S W Australia
    Int J Parasitol 27:739-46. 1997
    ..Horizontal gene transfer and principles for demonstrating horizontal character transfer are discussed...
  35. ncbi Evolutionary history of the Tricladida and the Platyhelminthes: an up-to-date phylogenetic and systematic account
    Marta Riutort
    Institut de Recerca de la Biodiversitat i Departament de Genètica, Universistat de Barcelona, Spain
    Int J Dev Biol 56:5-17. 2012
    Within the free-living platyhelminths, the triclads, or planarians, are the best-known group, largely as a result of long-standing and intensive research on regeneration, pattern formation and Hox gene expression...
  36. pmc Bacterial symbiosis maintenance in the asexually reproducing and regenerating flatworm Paracatenula galateia
    Ulrich Dirks
    Department of Marine Biology, University of Vienna, Vienna, Austria
    PLoS ONE 7:e34709. 2012
    ..This would justify both the codiversification between Paracatenula hosts and their Candidatus Riegeria symbionts, and the slow evolutionary rates observed for several symbiont genes...
  37. ncbi Body colors and algal distribution in the acoel flatworm Convolutriloba longifissura: histology and ultrastructure
    Euichi Hirose
    Department of Chemistry, Biology, and Marine Science, Faculty of Science, University of the Ryukyus, Nishihara, Japan
    Zoolog Sci 24:1241-6. 2007
    ..The ultrastructural features of these cells suggest a close relationship with Tetraselmis spp. The morphology of sagittocysts within the mantle is also described by means of scanning and transmission electron microscopy...
  38. ncbi Histological and histochemical characterization of the secretory cells of Choeradoplana iheringi Graff, 1899 (Platyhelminthes: Tricladida: Terricola)
    S de A Souza
    Instituto de Pesquisas de Planárias, Centro de Ciencias da Saude, Universidade do Vale do Rio dos Sinos, CEP 93022 000 São Leopoldo, RS, Brazil
    Braz J Biol 64:511-22. 2004
    ..This structure is located in the male or female atria in different specimens, and characterized by erythrophil, xanthophil, and/or mixed secretions associated with sperm...
  39. ncbi Unpredicted transmission strategy of Gyrodactylus salaris (Monogenea: Gyrodactylidae): survival and infectivity of parasites on dead hosts
    K Olstad
    Natural History Museum, Department of Zoology, University of Oslo, P O Box 1172, N 0318 Oslo, Norway
    Parasitology 133:33-41. 2006
    ..Hence, for G. salaris, dead infected hosts may increase the chances of successful transmission and be a potential important infection source in rivers and hatcheries...
  40. ncbi Lamellodiscus (Monogenea: Diplectanidae) parasites of Dentex macrophthalmus (Teleostei: Sparidae) from the North Atlantic coast of Africa, with a redescription of L. dentexi Aljoshkina, 1984, and description of three new species
    Arfang Diamanka
    Laboratory of Parasitology and Laboratory of Aquatic Animals Pathologies, Khaled bin Sultan Living Oceans Foundation, Department of Animal Biology, Faculty of Sciences and Technologies, University Cheikh Anta Diop, Dakar, Senegal
    Folia Parasitol (Praha) 58:17-26. 2011
    ..dentexi, L. virgula Euzet et Oliver, 1967 and L. obeliae Oliver, 1973 to form the "elongatus" type within the "elegans" group...
  41. pmc Myzostomida: a link between trochozoans and flatworms?
    I Eeckhaut
    Marine Biology Laboratory, University of Mons, Belgium
    Proc Biol Sci 267:1383-92. 2000
    ....
  42. ncbi Mode of transmission, host switching, and escape from the Red Queen by viviparous gyrodactylids (Monogenoidea)
    Walter A Boeger
    Departamento de Zoologia, Universidade Federal do Parana, Curitiba, Brazil
    J Parasitol 91:1000-7. 2005
    ..The absence of statistical differences between infrapopulations on isolated and grouped C. ehrhardti suggests that parasite dynamics may be influenced by factors other than continuous transmission in this host...
  43. ncbi Stem cells are differentially regulated during development, regeneration and homeostasis in flatworms
    Katrien De Mulder
    University of Innsbruck, Institute of Zoology and CMBI, Technikerstrasse 25, A 6020 Innsbruck, Austria
    Dev Biol 334:198-212. 2009
    ..Fourth, piwi expression in hatchlings further supports an embryonic formation of the germline in M. lignano. Our findings address new questions in flatworm stem cell research and provide a basis for comparison with higher organisms...
  44. ncbi Comparing host and parasite phylogenies: gyrodactylus flatworms jumping from goby to goby
    Tine Huyse
    Katholieke Universiteit Leuven, Laboratory of Aquatic Ecology, Ch De Beriotstraat 32, Leuven B 3000, Belgium
    Syst Biol 54:710-8. 2005
    ..This illustrates that phylogenetically conserved host-switching mimics the phylogenetic signature of co-speciation, confounding topology-based programs...
  45. pmc To be or not to be a flatworm: the acoel controversy
    Bernhard Egger
    Institute of Zoology and Center for Molecular Biosciences, University of Innsbruck, Innsbruck, Austria
    PLoS ONE 4:e5502. 2009
    ..By these data, both the inclusion of Acoela within Platyhelminthes, and their separation from flatworms as basal bilaterians are well-supported alternatives...
  46. ncbi Phylogenetic relationships among monogenean gill parasites (Dactylogyridea, Ancyrocephalidae) infesting tilapiine hosts (Cichlidae): systematic and evolutionary implications
    Laurent Pouyaud
    Laboratoire Genome, Populations, Interactions, Adaptations UMR 5171, cc 92, Universite Montpellier II, Sciences et Techniques du Languedoc, Place Eugene Bataillon, 34095 Montpellier, Cedex 5, France
    Mol Phylogenet Evol 38:241-9. 2006
    ....
  47. ncbi Phylogenetic distribution of microRNAs supports the basal position of acoel flatworms and the polyphyly of Platyhelminthes
    Lorenzo F Sempere
    Department of Biochemistry, Dartmouth Medical School, Hanover, NH 03755, USA
    Evol Dev 9:409-15. 2007
    ..Here, we examine another acoel, Symsagittifera roscoffensis, and three other platyhelminths. Our results show that the distribution of miRNAs in S. roscoffensis parallels that of Childia...
  48. ncbi Looks can deceive: molecular phylogeny of a family of flatworm ectoparasites (Monogenea: Capsalidae) does not reflect current morphological classification
    Elizabeth M Perkins
    Marine Parasitology Laboratory, School of Earth and Environmental Sciences DX 650 418, The University of Adelaide, North Terrace, Adelaide, SA 5005, Australia
    Mol Phylogenet Evol 52:705-14. 2009
    ..Consequently the current morphological classification shows little correspondence with the phylogenetic relationships within the family...
  49. ncbi The use of morphometric characters to discriminate specimens of laboratory-reared and wild populations of Gyrodactylus salaris and G. thymalli (Monogenea)
    Andrew P Shinn
    Institute of Aquaculture, University of Stirling, Stirling FK9 4LA, Scotland, UK
    Folia Parasitol (Praha) 51:239-52. 2004
    ..salaris Rauma population, all specimens were assigned to the correct population. Thus, populations of Gyrodactylus identified by mtDNA can also be discriminated using morphometric landmark distances...
  50. ncbi [Monogenean parasites from Clariidae (Teleostei, Siluriformes) in Cameroon: I. Description of two new species of Gyrodactylus from the Nyong basin]
    J Nack
    Laboratoire de Biologie Générale, Département de Biologie et Physiologie Animales, Faculte des Sciences, Universite de Yaounde I, Yaounde, Cameroun
    Parasite 12:213-20. 2005
    ..rysavyi, G. clarii and G. alberti, by the morphology and size of the haptorail sclerites. Their host specificity was discussed and appeared stenoxenous (mesostenoxenous)...
  51. pmc Platyhelminth mitochondrial and cytosolic redox homeostasis is controlled by a single thioredoxin glutathione reductase and dependent on selenium and glutathione
    Mariana Bonilla
    Catedra de Inmunologia, Facultad de Quimica Facultad de Ciencias, Instituto de Higiene, Universidad de la Republica, Piso 2, Montevideo, Uruguay
    J Biol Chem 283:17898-907. 2008
    ..These studies establish the selenium- and glutathione-dependent regulation of cytosolic and mitochondrial redox homeostasis through a single TGR enzyme in platyhelminths.
  52. ncbi Host specificity dynamics: observations on gyrodactylid monogeneans
    Tor A Bakke
    Zoological Museum, Sars Gate 1, N 0562, Oslo, Norway
    Int J Parasitol 32:281-308. 2002
    ..The origin of G. salaris, G. teuchis and G. thymalli is discussed in relation to glacial refugiums during the last ice age...
  53. ncbi Interactions between monogenean parasites and their fish hosts
    Kurt Buchmann
    Department of Veterinary Microbiology, Section of Fish Diseases, Royal Veterinary and Agricultural, 4 Stigbøjlen, DK 1870 C, Frederiksberg, Denmark
    Int J Parasitol 32:309-19. 2002
    ..Elevation of the host's production of adaptive and non-adaptive factors following monogenean infections of a certain duration may explain the acquired response...
  54. ncbi Speciation and host-parasite relationships in the parasite genus Gyrodactylus (Monogenea, Platyhelminthes) infecting gobies of the genus Pomatoschistus (Gobiidae, Teleostei)
    Tine Huyse
    Laboratory of Aquatic Ecology, Katholieke Universiteit Leuven, Ch De Beriotstraat 32, B 3000 Leuven, Belgium
    Int J Parasitol 33:1679-89. 2003
    ..Thus, allopatric speciation seems to be the dominant mode of speciation in this host-parasite system, with a possible case of sympatric speciation...
  55. ncbi Mitochondrial haplotype diversity of Gyrodactylus thymalli (Platyhelminthes; Monogenea): extended geographic sampling in United Kingdom, Poland, and Norway reveals further lineages
    Haakon Hansen
    Department of Zoology, Natural History Museum, University of Oslo, P O Box 1172 Blindern, N 0318, Oslo, Norway
    Parasitol Res 100:1389-94. 2007
    ..There is currently no reason to suspect that this parasite is a threat to Atlantic salmon in the UK, although its infectivity to salmon stocks in the UK has not been tested...
  56. pmc Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths
    Lucia Otero
    Catedra de Inmunologia, Facultad de Quimica, Instituto de Higiene, Universidad de la Republica, Avda, A, Navarro 3051, Montevideo, Uruguay
    BMC Genomics 11:237. 2010
    ..Little is known regarding the genomic structure of flatworm TGRs, the expression of TGR variants and whether the absence of conventional thioredoxin and glutathione systems is a signature of the entire platyhelminth phylum...
  57. ncbi Embryonic development in the primitive bilaterian Neochildia fusca: normal morphogenesis and isolation of POU genes Brn-1 and Brn-3
    Nallur B Ramachandra
    Department of Molecular, Cell, and Developmental Biology, University of California at Los Angeles, 90095 1606, USA
    Dev Genes Evol 212:55-69. 2002
    ..These flatworms, by virtue of their distinct morphology, development and phylogenetically basal placement, are likely to provide key insights into the interpretation of the evolution of metazoan neural architecture...
  58. ncbi Inferring the ancestral function of the posterior Hox gene within the bilateria: controlling the maintenance of reproductive structures, the musculature and the nervous system in the acoel flatworm Isodiametra pulchra
    Eduardo Moreno
    Departament de Genetica, Universitat de Barcelona, Av Diagonal 645, 08028 Barcelona, Spain
    Evol Dev 12:258-66. 2010
    ..We conclude, therefore, that the posterior Hox genes were used to specify and maintain defined anatomical regions within the AP axis of animals since the beginning of bilaterian evolution...
  59. ncbi The description of Gyrodactylus corleonis sp. n. and G. neretum sp. n. (Platyhelminthes: Monogenea) with comments on other gyrodactylids parasitising pipefish (Pisces: Syngnathidae)
    Giuseppe Paladini
    Institute of Aquaculture, University of Stirling, Stirling, FK9 4LA, Scotland, UK
    Folia Parasitol (Praha) 57:17-30. 2010
    ..neretum has a 1:2 hamulus point:shaft ratio and a rectangular-shaped ventral bar. A redescription of the haptoral hard parts of the four species previously recorded on pipefish is also presented...
  60. ncbi Parasite speciation within or between host species?--phylogenetic evidence from site-specific polystome monogeneans
    D T Littlewood
    Department of Zoology, Natural History Museum, London, U K
    Int J Parasitol 27:1289-97. 1997
    ....
  61. ncbi Interspecific and intraspecific interactions in the monogenean communities of fish: a question of study scale?
    A Karvonen
    Department of Biological and Environmental Science, P O Box 35, FI 40014 University of Jyvaskyla, Finland
    Parasitology 134:1237-42. 2007
    ....
  62. ncbi Abundance-prevalence relationship of gill congeneric ectoparasites: testing the core satellite hypothesis and ecological specialisation
    Andrea Simkova
    Centre de Biologie et d Ecologie Tropicale et Mediterraneenne, UMR 5555 CNRS, Universite de Perpignan, Avenue de Villeneuve, 66860 Perpignan Cedex, France
    Parasitol Res 88:682-6. 2002
    ..However, generalists were found to be more widely distributed among hosts and had higher abundances than specialists, which supports the ecological specialisation hypothesis...
  63. ncbi First report of the invasive eel pest Pseudodactylogyrus bini in North America and in wild American eels
    C J Hayward
    Department of Aquatic Bioscience, Graduate School of Agriculture, University of Tokyo, Japan
    Dis Aquat Organ 44:53-60. 2001
    ..crassus) are likely to continue to colonise other regions of the world...
  64. ncbi The Macrostomum lignano EST database as a molecular resource for studying platyhelminth development and phylogeny
    Joshua Morris
    Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA 90095, USA
    Dev Genes Evol 216:695-707. 2006
    ..Expression of these genes is shown in the context of the neuropile/muscle system...
  65. ncbi Molecular phylogeny of monogeneans parasitizing African freshwater Cichlidae inferred from LSU rDNA sequences
    Monika Mendlová
    Department of Botany and Zoology, Faculty of Science, Masaryk University, Kotlarska 2, 611 37, Brno, Czech Republic
    Parasitol Res 107:1405-13. 2010
    ..e., the parasite species does not live in cichlids, which suggests that endoparasitism in cichlid monogeneans is not an ancestral feature...
  66. ncbi Two new species of Gyrodactylus von Nordmann, 1832 (Monogenea: Gyrodactylidae) parasitizing Girardinichthys multiradiatus (Cyprinodontiformes: Goodeidae), an endemic freshwater fish from central Mexico
    Carlos A Mendoza-Palmero
    Laboratorio de Helmintologia, Instituto de Biologia, Universidad Nacional Autonoma de Mexico, Apartado Postal 70 153, C P 04510, DF Mexico
    J Parasitol 95:315-8. 2009
    ..mexicanus and from other species of Gyrodactylus on the North American continent by having anchors with a sclerite on the superficial root and robust hooks with a straight shaft and a recurved point...
  67. ncbi DNA taxonomy and barcoding of monogenean parasites: lessons from Gyrodactylus
    Haakon Hansen
    Natural History Museum, Department for Zoology, University of Oslo, PO Box 1172, Blindern, NO 0318 Oslo, Norway
    Trends Parasitol 23:363-7. 2007
    ....
  68. ncbi Mitochondrial DNA variation of Gyrodactylus spp (Monogenea, Gyrodactylidae) populations infecting Atlantic salmon, grayling, and rainbow trout in Norway and Sweden
    Haakon Hansen
    Department of Zoology, University of Oslo, PO Box 1172, Blindern, N 0318, Oslo, Norway
    Int J Parasitol 33:1471-8. 2003
    ..A minimum of three independent introductions of G. salaris and two independent introductions of G. thymalli are supported. This is congruent with earlier hypotheses on the introduction of G. salaris and G. thymalli into Norway...
  69. ncbi Morphological and molecular taxonomy of a new species of Fundulotrema and comments on Gyrodactylus stephanus (Monogenea: Gyrodactylidae) from Fundulus heteroclitus (Actinopterygii: Cyprinodontiformes) in Nova Scotia, Canada
    Stanley D King
    Department of Biology, Saint Mary s University, Halifax, Nova Scotia B3H 3C3, Canada
    J Parasitol 95:846-9. 2009
    ..This new material provides previously unrecorded information on the attributes of the ventral bar, marginal hooks, and also clarifies the structure of the male copulatory organ (MCO)...
  70. ncbi Three new species, Lamellodiscus tubulicornis n. sp., L. magnicornis n. sp. and L. parvicornis n. sp. (Monogenea: Diplectanidae) from Gymnocranius spp. (Lethrinidae: Monotaxinae) off New Caledonia, with the proposal of the new morphological group 'tubulic
    Jean Lou Justine
    Equipe Biogéographie Marine Tropicale, Unité Systématique, Adaptation, Evolution CNRS, UPMC, MNHN, IRD, Institut de Recherche pour le Developpement, BP A5, 98848, Noumea Cedex, New Caledonia
    Syst Parasitol 75:159-79. 2010
    ..The generic diagnosis of Lamellodiscus given by Amine & Euzet (2005) is amended to include species with elongate eggs...
  71. ncbi Diplectanid parasites of Lithognathus mormyrus (L.) (Teleostei: Sparidae) from the Mediterranean Sea, with the description of Lamellodiscus flagellatus n. sp. (Monogenea: Diplectanidae)
    Lobna Boudaya
    Laboratoire de Biodiversité et Ecosystèmes Aquatiques, Faculte des Sciences de Sfax, Sfax, Tunisia
    Syst Parasitol 74:149-59. 2009
    ..The status of L. ignoratus Palombi, 1943, another species from Lithognathus mormyrus, is discussed. A possible scenario for the synxenic speciation of these congeneric parasites of L. mormyrus is proposed...
  72. ncbi The free-living flatworm Macrostomum lignano: a new model organism for ageing research
    Stijn Mouton
    Department of Biology, Ghent University, Ghent, Belgium
    Exp Gerontol 44:243-9. 2009
    ..We also give an overview of the available experimental tools that allow a multidisciplinary approach for studying ageing in M. lignano...
  73. pmc Coordinated spatial and temporal expression of Hox genes during embryogenesis in the acoel Convolutriloba longifissura
    Andreas Hejnol
    Kewalo Marine Laboratory, PBRC, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    BMC Biol 7:65. 2009
    ..As acoels appear to represent the sister group to the remaining Bilateria (Nephrozoa), investigating Hox gene expression will provide an insight into the ancestral features of the Hox genes in metazoan evolution...
  74. ncbi Functional genomics for parasitic nematodes and platyhelminths
    A Aziz Aboobaker
    Department of Integrative Biology, 3060 VLSB No 3140, University of California Berkeley, Berkeley, CA 94720 3140, USA
    Trends Parasitol 20:178-84. 2004
  75. ncbi The Hox gene complement of acoel flatworms, a basal bilaterian clade
    Charles E Cook
    University Museum of Zoology, Department of Zoology, Downing Street, Cambridge CB2 3EJ, UK
    Evol Dev 6:154-63. 2004
    ....
  76. ncbi The complete mitochondrial genomes of Schistosoma haematobium and Schistosoma spindale and the evolutionary history of mitochondrial genome changes among parasitic flatworms
    D Timothy J Littlewood
    Department of Zoology, The Natural History Museum, Cromwell Road, London SW7 5BD, UK
    Mol Phylogenet Evol 39:452-67. 2006
    ..Denser and wider taxon sampling of mt genomes across the Platyhelminthes will validate these putative characters...
  77. pmc Voltage-gated calcium channel subunits from platyhelminths: potential role in praziquantel action
    Michael C Jeziorski
    Instituto de Neurobiologia, Universidad Nacional Autonoma de Mexico, Campus UNAM UAQ Juriquilla, Queretaro, Qro 76001, Mexico
    Int J Parasitol 36:625-32. 2006
    ..We also present evidence that Ca(v)betavar homologs are found in other praziquantel-sensitive platyhelminths such as the pork tapeworm, Taenia solium, and that these variant beta subunits may thus represent a ..
  78. pmc The regeneration capacity of the flatworm Macrostomum lignano--on repeated regeneration, rejuvenation, and the minimal size needed for regeneration
    B Egger
    Ultrastructural Research and Evolutionary Biology, Institute of Zoology, University of Innsbruck, Innsbruck, Austria
    Dev Genes Evol 216:565-77. 2006
    ..In hatchlings only 1,500 cells, including 50 neoblasts, are needed for regeneration. The life span of untreated M. lignano was determined to be about 10 months...
  79. ncbi Immunogold-labeled S-phase neoblasts, total neoblast number, their distribution, and evidence for arrested neoblasts in Macrostomum lignano (Platyhelminthes, Rhabditophora)
    A Bode
    Institute of Zoology and Limnology, University of Innsbruck, Technikerstrasse 25, 6020 Innsbruck, Austria
    Cell Tissue Res 325:577-87. 2006
    ..Immunogold-labeled sections showed that nearly 70% of S-phase cells were in direct contact or within 5 microm from nerve cords...
  80. ncbi Inhibitory effects of antiparkinsonian drugs and caspase inhibitors in a parkinsonian flatworm model
    Yoshihisa Kitamura
    Department of Neurobiology, Kyoto Pharmaceutical University, Kyoto, Japan
    J Pharmacol Sci 92:137-42. 2003
    ..These results suggest that the degeneration of planarian dopaminergic system induced by rotenone or MPTP may be mediated through caspase-like activation...
  81. pmc Back in time: a new systematic proposal for the Bilateria
    Jaume Baguna
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain
    Philos Trans R Soc Lond B Biol Sci 363:1481-91. 2008
    ..A new systematic scheme for the Bilateria that includes the Cnidaria is suggested and its main implications discussed...
  82. ncbi Hox and ParaHox genes in Nemertodermatida, a basal bilaterian clade
    Eva Jimenez-Guri
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Int J Dev Biol 50:675-9. 2006
    ....
  83. ncbi Spiralian phylogenomics supports the resurrection of Bryozoa comprising Ectoprocta and Entoprocta
    Bernhard Hausdorf
    Zoological Museum, University of Hamburg, Hamburg, Germany
    Mol Biol Evol 24:2723-9. 2007
    ....
  84. ncbi The embryonic development of the flatworm Macrostomum sp
    Joshua Morris
    Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles 90095, USA
    Dev Genes Evol 214:220-39. 2004
    ..The embryo adopts its final shape during stages 7 and 8, characterized by the morphallactic lengthening of the body into a U-shaped form and the condensation of the nervous system...
  85. ncbi Gyro-scope: an individual-based computer model to forecast gyrodactylid infections on fish hosts
    C Van Oosterhout
    Molecular Ecology and Fisheries Genetics Laboratory, University of Hull, Hull HU6 7RX, UK
    Int J Parasitol 38:541-8. 2008
    ..The model is a useful tool to forecast the development of gyrodactylid infections on single hosts and make predictions about optimal life history strategies of parasites...
  86. ncbi Triploblastic relationships with emphasis on the acoelomates and the position of Gnathostomulida, Cycliophora, Plathelminthes, and Chaetognatha: a combined approach of 18S rDNA sequences and morphology
    G Giribet
    Division of Invertebrate Zoology, American Museum of Natural History, New York, New York 10024 5192, USA
    Syst Biol 49:539-62. 2000
    ....
  87. pmc Acoel flatworms are not platyhelminthes: evidence from phylogenomics
    Hervé Philippe
    Canadian Institute for Advanced Research, Centre Robert Cedergren, Departement de Biochimie, Universite de Montreal, Montreal, Quebec, Canada
    PLoS ONE 2:e717. 2007
    ....
  88. ncbi Complete sequence of the mitochondrial genome of the tapeworm Hymenolepis diminuta: gene arrangements indicate that Platyhelminths are Eutrochozoans
    M von Nickisch-Rosenegk
    Department of Biology, University of Michigan, USA
    Mol Biol Evol 18:721-30. 2001
    ..diminuta with those previously published supports a phylogenetic position of flatworms as members of the Eutrochozoa, rather than placing them basal to either a clade of protostomes or a clade of coelomates...
  89. ncbi Neurobiology of the basal platyhelminth Macrostomum lignano: map and digital 3D model of the juvenile brain neuropile
    Joshua Morris
    Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA 90095, USA
    Dev Genes Evol 217:569-84. 2007
    ..This study will aid in the documentation and interpretation of patterns of gene expression, as well as functional studies, in the developing Macrostomum brain...
  90. ncbi Stem cell dynamics during growth, feeding, and starvation in the basal flatworm Macrostomum sp. (Platyhelminthes)
    Katharina T Nimeth
    Division of Ultrastructure Research and Developmental Biology, Department of Zoology and Limnology, University Innsbruck, Innsbruck, Austria
    Dev Dyn 230:91-9. 2004
    ..Neoblasts that pass through S-phase led to a maximum of mitoses after 48 hr. Our results allow deeper insight into cellular dynamics of an ancestral bilaterian stem cell system of a basal Platyhelminth...
  91. ncbi Ontogeny of the complex sperm in the macrostomid flatworm Macrostomum lignano (Macrostomorpha, Rhabditophora)
    Maxime Willems
    Nematology Section, Department of Biology, Ghent University, B 9000 Ghent, Belgium
    J Morphol 270:162-74. 2009
    ..The implications of the development of this bristle complex on both sperm maturation and the evolution and function of the bristles are discussed. The assumed homology between bristles and flagellae questioned...
  92. ncbi [Architectonics of the central nervous system in Acoela, Plathelminthes, and Rotifera]
    E A Kotikova
    Zh Evol Biokhim Fiziol 44:83-93. 2008
    ..A special attention will be paid to the Acoela phylogenesis, based on molecular-biology data and results of study of their nervous system...
  93. ncbi Production and characterisation of cell- and tissue-specific monoclonal antibodies for the flatworm Macrostomum sp
    Peter Ladurner
    Institute of Zoology and Limnology, University of Innsbruck, Technikerstrasse 25, 6020 Innsbruck, Austria
    Histochem Cell Biol 123:89-104. 2005
    ..as a suitable model organism for comparative analyses within Platyhelminthes and to Drosophila and C. elegans...
  94. ncbi The dawn of bilaterian animals: the case of acoelomorph flatworms
    Jaume Baguna
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain
    Bioessays 26:1046-57. 2004
    ..This reconstruction backs the old planuloid-acoeloid hypothesis and may help our understanding of the evolution of body axes, Hox genes and the Cambrian explosion...
  95. ncbi Mitochondrial genome data support the basal position of Acoelomorpha and the polyphyly of the Platyhelminthes
    Inaki Ruiz-Trillo
    Departament de Genetica, Universitat de Barcelona, Av Diagonal, 645, 08028 Barcelona, Spain
    Mol Phylogenet Evol 33:321-32. 2004
    ..Therefore, the Platyhelminthes, as traditionally constituted, is a polyphyletic phylum...
  96. ncbi Tracking the origins of the bilaterian Hox patterning system: insights from the acoel flatworm Symsagittifera roscoffensis
    Eduardo Moreno
    Department de Genetica, Universitat de Barcelona, 08028 Barcelona, Spain
    Evol Dev 11:574-81. 2009
    ..The basic set of Hox genes in acoels and their coarse nested spatial deployment might be the first indicators of the role of Hox genes in the evolution of bilateral symmetry and AP positional identity from a hypothetical radial ancestor...
  97. ncbi Linked thioredoxin-glutathione systems in platyhelminths
    Gustavo Salinas
    Catedra de Inmunologia, Facultad de Quimica, Instituto de Higiene, Avda A Navarro 3051, Montevideo, CP 11600, Uruguay
    Trends Parasitol 20:340-6. 2004
    ..Analysis of published data and expressed-sequence tag databases indicates the presence of linked thioredoxin-glutathione systems in the cytosolic and mitochondrial compartments of these parasites...
  98. ncbi Monogeneans from Pangasiidae (Siluriformes) in Southeast Asia: III. Five new species of Thaparocleidus Jain, 1952 (Ancylodiscoididae) from Pangasius bocourti, P. djambal and P. hypophthalmus
    A Pariselle
    IRD ex ORSTOM, Catfish Asia Project, Instalasi Penelitian Perikanan Air Tawar, Jalan Ragunan Pasar Minggu, P O Box 7220 jkspm, Jakarta 12540, Indonesia
    Parasite 9:207-17. 2002
    ..combesi n. sp., T. euzeti n. sp., T. komarudini n. sp. and T. sadilii n. sp. P. hypophthalmus: T. caecus, T. siamensis (Lim, 1990) and T. vietnamensis n. sp. P. gigas: no Monogenea were found on this host species...
  99. ncbi Monogeneans from Pangasiidae (Siluriformes) in Southeast Asia: VI. Pangasitrema camillae n. g., n. sp. (Monogenea, Ancylodiscoididae), from Pangasius polyuranodon
    A Pariselle
    Catfish Asia Project, Instalasi Penelitian Perikanan Air Tawar, Jalan Ragunan Pasar Minggu, P O Box 7220 jkspm, Jakarta 12540, Indonesia
    Parasite 11:149-52. 2004
    ..Among Ancylodiscoididae, the genus has several distinguishing features: the reduced size of the haptor, the morphology and size of gripi, the absence of a ventral transversal bar and of a cuneus associated with dorsal gripi...
  100. ncbi A new genus of dactylogyrid from the gills of Galaxias maculatus (Osmeriformes: Galaxiidae) in Maullín Basin, Patagonia, Chile
    Gustavo P Viozzi
    Laboratorio de Parasitologia, Centro Regional Universitario Bariloche, Universidad Nacional del Comahue, Quintral 1250, 8400 Bariloche, Argentina
    J Parasitol 93:542-4. 2007
    ..Inserotrema puyei n. sp. infects gills of G. maculatus from Llanquihue Lake, Maullín River, and Maullín Estuary. This is the first species of Ancyrocephalinae described from gills of a galaxiid...
  101. ncbi Monogeneans from Pangasiidae (Siluriformes) in Southeast Asia: IV. Five new species of Thaparocleidus Jain, 1952 (Ancylodiscoididae) from Pangasius krempfi, P. kunyit, P. mekongensis and P. sabahensis
    A Pariselle
    IRD ex ORSTOM, Catfish Asia Project, Instalasi Penelitian Perikanan Air Tawar, Jalan Ragunan Pasar Minggu, PO Box 7220 jkspm, Jakarta 12540, Indonesia
    Parasite 9:315-24. 2002
    ..phuongi phuongi n. sub-sp., T. phuongi malaysiensis n. sub-sp. and T. phuongi indonesiensis n. sub-sp...

Research Grants5

  1. Novel targets and drugs for the control of platyhelminth infections
    MARCOS GUSTAVO SALINAS; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Parasitic infections caused by flatworms (platyhelminths) are neglected diseases and a major cause of disability, mortality and significant economic losses in many developing countries...
  2. Assaying the Anthelmintic Potential of a Novel Flatworm-Specific GPCR Family
    Timothy A Day; Fiscal Year: 2013
    ..b>Platyhelminths (flatworms) of the genus Schistosoma are notorious for topping the statistics for negative effects on human ..
  3. Transformation of C. elegans with a novel schistosome calcium channel subunit
    Robert M Greenberg; Fiscal Year: 2010
    ..This b subunit subtype has been found to date only in platyhelminths;PZQ is not effective against nematodes, and nematode genomes do not contain this variant Cav channel b subunit...
  4. POTENTIAL TARGETS FOR NEW ANTISCHISTOSOMAL AGENTS
    Robert Greenberg; Fiscal Year: 2006
    ..These experiments may eventually lead to new chemotherapeutic approaches to treating schistosomiasis. ..
  5. Function and pharmacology of schistosome multidrug resistance proteins
    Robert M Greenberg; Fiscal Year: 2010
    ..We propose to use several approaches to determine the properties of one such schistosome molecule, P-glycoprotein, which, in vertebrates, is also involved in resistance to a broad array of drugs. ..