moths

Summary

Summary: Insects of the suborder Heterocera of the order LEPIDOPTERA.

Top Publications

  1. pmc Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis
    Eleftherios Mylonakis
    Division of Infectious Diseases, Massachusetts General Hospital, Gray Jackson 504, 55 Fruit St, Boston, Massachusetts 02114, USA
    Infect Immun 73:3842-50. 2005
  2. pmc A large-scale, higher-level, molecular phylogenetic study of the insect order Lepidoptera (moths and butterflies)
    Jerome C Regier
    Institute for Bioscience and Biotechnology Research, University of Maryland, College Park, Maryland, USA
    PLoS ONE 8:e58568. 2013
  3. ncbi Estimating the economic cost of one of the world's major insect pests, Plutella xylostella (Lepidoptera: Plutellidae): just how long is a piece of string?
    Myron P Zalucki
    School of Biological Sciences, The University of Queensland, Brisbane, Australia, 4072
    J Econ Entomol 105:1115-29. 2012
  4. ncbi Suppression of cotton bollworm in multiple crops in China in areas with Bt toxin-containing cotton
    Kong Ming Wu
    State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, People s Republic of China
    Science 321:1676-8. 2008
  5. ncbi Field-evolved insect resistance to Bt crops: definition, theory, and data
    Bruce E Tabashnik
    Department of Entomology, University of Arizona, Tucson, AZ 85721, USA
    J Econ Entomol 102:2011-25. 2009
  6. ncbi The complete mitochondrial genome of the tobacco hornworm, Manduca sexta, (Insecta: Lepidoptera: Sphingidae), and an examination of mitochondrial gene variability within butterflies and moths
    Stephen L Cameron
    Australian National Insect Collection and CSIRO Entomology, Black Mountain Laboratories, Canberra, ACT, Australia
    Gene 408:112-23. 2008
  7. ncbi Pyrosequencing the Manduca sexta larval midgut transcriptome: messages for digestion, detoxification and defence
    Y Pauchet
    School of Biosciences, University of Exeter, Cornwall Campus, Penryn, UK
    Insect Mol Biol 19:61-75. 2010
  8. ncbi Wax moth larva (Galleria mellonella): an in vivo model for assessing the efficacy of antistaphylococcal agents
    Andrew P Desbois
    Biomedical Sciences Research Complex, School of Biology, The North Haugh, University of St Andrews, Fife, KY16 9ST, UK
    J Antimicrob Chemother 66:1785-90. 2011
  9. pmc A receptor and binding protein interplay in the detection of a distinct pheromone component in the silkmoth Antheraea polyphemus
    Maike Forstner
    University of Hohenheim, Institute of Physiology, Stuttgart, Germany
    Int J Biol Sci 5:745-57. 2009
  10. ncbi A divergent gene family encoding candidate olfactory receptors of the moth Heliothis virescens
    Jurgen Krieger
    University of Hohenheim, Institute of Physiology 230, Garbenstr 30, 70599 Stuttgart, Germany
    Eur J Neurosci 16:619-28. 2002

Research Grants

Detail Information

Publications406 found, 100 shown here

  1. pmc Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis
    Eleftherios Mylonakis
    Division of Infectious Diseases, Massachusetts General Hospital, Gray Jackson 504, 55 Fruit St, Boston, Massachusetts 02114, USA
    Infect Immun 73:3842-50. 2005
    ..The G. mellonella-C. neoformans pathogenicity model may be a substitute for mammalian models of infection with C. neoformans and may facilitate the in vivo study of fungal virulence and efficacy of antifungal therapies...
  2. pmc A large-scale, higher-level, molecular phylogenetic study of the insect order Lepidoptera (moths and butterflies)
    Jerome C Regier
    Institute for Bioscience and Biotechnology Research, University of Maryland, College Park, Maryland, USA
    PLoS ONE 8:e58568. 2013
    ..We present the most comprehensive molecular analysis of lepidopteran phylogeny to date, focusing on relationships among superfamilies...
  3. ncbi Estimating the economic cost of one of the world's major insect pests, Plutella xylostella (Lepidoptera: Plutellidae): just how long is a piece of string?
    Myron P Zalucki
    School of Biological Sciences, The University of Queensland, Brisbane, Australia, 4072
    J Econ Entomol 105:1115-29. 2012
    ....
  4. ncbi Suppression of cotton bollworm in multiple crops in China in areas with Bt toxin-containing cotton
    Kong Ming Wu
    State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, People s Republic of China
    Science 321:1676-8. 2008
    ..Our data suggest that Bt cotton not only controls H. armigera on transgenic cotton designed to resist this pest but also may reduce its presence on other host crops and may decrease the need for insecticide sprays in general...
  5. ncbi Field-evolved insect resistance to Bt crops: definition, theory, and data
    Bruce E Tabashnik
    Department of Entomology, University of Arizona, Tucson, AZ 85721, USA
    J Econ Entomol 102:2011-25. 2009
    ....
  6. ncbi The complete mitochondrial genome of the tobacco hornworm, Manduca sexta, (Insecta: Lepidoptera: Sphingidae), and an examination of mitochondrial gene variability within butterflies and moths
    Stephen L Cameron
    Australian National Insect Collection and CSIRO Entomology, Black Mountain Laboratories, Canberra, ACT, Australia
    Gene 408:112-23. 2008
    ....
  7. ncbi Pyrosequencing the Manduca sexta larval midgut transcriptome: messages for digestion, detoxification and defence
    Y Pauchet
    School of Biosciences, University of Exeter, Cornwall Campus, Penryn, UK
    Insect Mol Biol 19:61-75. 2010
    ..Similar studies of other tissues will allow for a tissue by tissue description of the M. sexta transcriptome and will form an essential complimentary step on the road to genome sequencing and annotation...
  8. ncbi Wax moth larva (Galleria mellonella): an in vivo model for assessing the efficacy of antistaphylococcal agents
    Andrew P Desbois
    Biomedical Sciences Research Complex, School of Biology, The North Haugh, University of St Andrews, Fife, KY16 9ST, UK
    J Antimicrob Chemother 66:1785-90. 2011
    ..To investigate whether the wax moth larva, Galleria mellonella, is a suitable host for assessing the in vivo efficacy of antistaphylococcal agents against Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) infections...
  9. pmc A receptor and binding protein interplay in the detection of a distinct pheromone component in the silkmoth Antheraea polyphemus
    Maike Forstner
    University of Hohenheim, Institute of Physiology, Stuttgart, Germany
    Int J Biol Sci 5:745-57. 2009
    Male moths respond to conspecific female-released pheromones with remarkable sensitivity and specificity, due to highly specialized chemosensory neurons in their antennae...
  10. ncbi A divergent gene family encoding candidate olfactory receptors of the moth Heliothis virescens
    Jurgen Krieger
    University of Hohenheim, Institute of Physiology 230, Garbenstr 30, 70599 Stuttgart, Germany
    Eur J Neurosci 16:619-28. 2002
    The antennae of moths have been an invaluable model for studying the principles of odour perception...
  11. pmc Characterization of the complete mitochondrial genome of the giant silkworm moth, Eriogyna pyretorum (Lepidoptera: Saturniidae)
    Shao Tong Jiang
    Department of Biotechnology, Hefei University of Technology, Hefei, People s Republic of China
    Int J Biol Sci 5:351-65. 2009
    ..As has been previously suggested, Bombycidae (Bombyx mori and Bombyx mandarina), Sphingoidae (Manduca sexta) and Saturniidae (Antheraea pernyi, Antheraea yamamai, E. pyretorum and Caligula boisduvalii) formed a group...
  12. pmc Putative chemosensory receptors of the codling moth, Cydia pomonella, identified by antennal transcriptome analysis
    Jonas M Bengtsson
    Research and Innovation Centre, Fondazione Edmund Mach, San Michele all Adige, Italy
    PLoS ONE 7:e31620. 2012
    ..Our results open for functional characterization of the chemosensory receptors of C. pomonella, with potential for new or refined applications of semiochemicals for control of this pest insect...
  13. ncbi Areawide suppression of European corn borer with Bt maize reaps savings to non-Bt maize growers
    W D Hutchison
    Department of Entomology, University of Minnesota, St Paul, MN 55108, USA
    Science 330:222-5. 2010
    ..9 billion for non-Bt maize growers. These results affirm theoretical predictions of pest population suppression and highlight economic incentives for growers to maintain non-Bt maize refugia for sustainable insect resistance management...
  14. pmc Parallel evolution of Bacillus thuringiensis toxin resistance in lepidoptera
    Simon W Baxter
    Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, United Kingdom
    Genetics 189:675-9. 2011
    ..Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function...
  15. pmc Timing and patterns in the taxonomic diversification of Lepidoptera (butterflies and moths)
    Niklas Wahlberg
    Department of Biology, University of Turku, Turku, Finland
    PLoS ONE 8:e80875. 2013
    ..Almost all extant families appear to have begun diversifying soon after the Cretaceous/Paleogene event 65.51 mya. ..
  16. ncbi The effect of piperonyl butoxide on pyrethroid-resistance-associated esterases in Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae)
    Susan J Young
    Rothamsted Research, Harpenden, Hertfordshire, AL5 2JQ, UK
    Pest Manag Sci 61:397-401. 2005
    ..It would also be expected that restoration of efficacy with other conventional insecticides, currently compromised by esterase-based resistance mechanisms, would occur...
  17. pmc Candidate olfaction genes identified within the Helicoverpa armigera Antennal Transcriptome
    Yang Liu
    State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China
    PLoS ONE 7:e48260. 2012
    ..Our results allow a systematic functional analysis across much of conventional ORs repertoire and newly reported IRs mediating the key olfaction-mediated behaviors of H. armigera...
  18. pmc Early warning of cotton bollworm resistance associated with intensive planting of Bt cotton in China
    Haonan Zhang
    College of Plant Protection, Nanjing Agricultural University, Nanjing, China
    PLoS ONE 6:e22874. 2011
    ..This early warning may spur proactive countermeasures, including a switch to transgenic cotton producing two or more toxins distinct from Cry1A toxins...
  19. ncbi Maize landraces recruit egg and larval parasitoids in response to egg deposition by a herbivore
    Amanuel Tamiru
    Habitat Management Programme, International Centre of Insect Physiology and Ecology, PO Box 30, Mbita Point, Kenya
    Ecol Lett 14:1075-83. 2011
    ..We found that egg deposition by stemborer moths (Chilo partellus) on maize landrace varieties caused emission of HIPVs that attract parasitic wasps...
  20. pmc Extensive synteny conservation of holocentric chromosomes in Lepidoptera despite high rates of local genome rearrangements
    E d'Alençon
    Unité Mixte de Recherche 1231, Institut National de la Recherche Agronomique, Universite Montpellier II, 34095 Montpellier, France
    Proc Natl Acad Sci U S A 107:7680-5. 2010
    ..We sequenced BACs from two major pests, the noctuid moths Helicoverpa armigera and Spodoptera frugiperda, corresponding to 15 regions distributed on 11 B...
  21. ncbi Galleria mellonella as an alternative infection model for Yersinia pseudotuberculosis
    Olivia L Champion
    School of Biosciences, University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter EX4 4QD, UK
    Microbiology 155:1516-22. 2009
    ..mellonella. The complemented mutant regained all phenotypic properties associated with SodC, confirming the important role of this metalloenzyme in two Y. pseudotuberculosis infection models...
  22. ncbi Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae
    Marc Brennan
    Medical Mycology Unit, Department of Biology, National University of Ireland, Co Kildare, Maynooth, Ireland
    FEMS Immunol Med Microbiol 34:153-7. 2002
    ..The correlation with virulence measured in the mouse infection system suggests that Galleria may provide a convenient and inexpensive model for the in vivo screening of mutants of C. albicans...
  23. pmc An ABC transporter mutation is correlated with insect resistance to Bacillus thuringiensis Cry1Ac toxin
    Linda J Gahan
    Department of Biological Sciences, Clemson University, Clemson, South Carolina, United States of America
    PLoS Genet 6:e1001248. 2010
    ..This weakness could be exploited to manage this mechanism of Bt resistance in the field...
  24. pmc Genes encoding candidate pheromone receptors in a moth (Heliothis virescens)
    J Krieger
    Institute of Physiology 230, University of Hohenheim, Garbenstrasse 30, 70599 Stuttgart, Germany
    Proc Natl Acad Sci U S A 101:11845-50. 2004
    The remarkable responsiveness of male moths to female released pheromones is based on the extremely sensitive and selective reaction of highly specialized sensory cells in the male antennae...
  25. ncbi Identification of receptors of main sex-pheromone components of three Lepidopteran species
    Hidefumi Mitsuno
    Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan
    Eur J Neurosci 28:893-902. 2008
    Male moths discriminate conspecific female-emitted sex pheromones...
  26. pmc Increased gene sampling strengthens support for higher-level groups within leaf-mining moths and relatives (Lepidoptera: Gracillariidae)
    Akito Y Kawahara
    Department of Entomology, University of Maryland, College Park, MD, USA
    BMC Evol Biol 11:182. 2011
    ..We target Gracillariidae, a Cretaceous-age (~100 Ma) group of leaf-mining moths to test whether the strategy of adding genes for a subset of taxa can improve branch support for deep nodes...
  27. ncbi Methods for using Galleria mellonella as a model host to study fungal pathogenesis
    Beth Burgwyn Fuchs
    Division of Infectious, Massachusetts General Hospital, Boston, MA, USA
    Virulence 1:475-82. 2010
    ..mellonella. The protocols presented herein can be adapted to the study of other fungal pathogens using G. mellonella as an infection model...
  28. pmc Galleria mellonella as a model system to study Acinetobacter baumannii pathogenesis and therapeutics
    Anton Y Peleg
    Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Antimicrob Agents Chemother 53:2605-9. 2009
    ..G. mellonella is a relatively simple, nonmammalian model system that can be used to facilitate the in vivo study of host-pathogen interactions in A. baumannii and the efficacy of antibacterial agents...
  29. ncbi Assortative mating in sympatric host races of the European corn borer
    Thibaut Malausa
    Laboratoire Dynamique de la Biodiversité, Université P Sabatier Toulouse III, UMR CNRS 5172, 31 062 Toulouse Cedex 04, France
    Science 308:258-60. 2005
    ....
  30. ncbi Candidate pheromone receptors provide the basis for the response of distinct antennal neurons to pheromonal compounds
    Ewald Grosse-Wilde
    University of Hohenheim, Institute of Physiology 230, Garbenstrasse 30, 70599 Stuttgart, Germany
    Eur J Neurosci 25:2364-73. 2007
    ..The data provide further evidence that a combination of a distinct receptor type and binding protein underlie the specific response observed in the detection of a pheromone component in vivo...
  31. pmc Semi-selective fatty acyl reductases from four heliothine moths influence the specific pheromone composition
    Asa K Hagström
    Pheromone Group, Department of Biology, Lund University, Lund, Sweden
    PLoS ONE 7:e37230. 2012
    ..Most heliothine moths use sex pheromones with (Z)-11-hexadecenal as the major component in combination with minor fatty aldehydes and ..
  32. pmc Functional consequences of sequence variation in the pheromone biosynthetic gene pgFAR for Ostrinia moths
    Jean Marc Lassance
    Department of Biology, Lund University, SE 22362 Lund, Sweden
    Proc Natl Acad Sci U S A 110:3967-72. 2013
    ..In insects and moths in particular, the use of structurally similar components in different blend ratios is usually sufficient to ..
  33. ncbi Effects of Bt cotton and crylac toxin on survival and development of pink bollworm (Lepidoptera: Gelechiidae)
    Y B Liu
    Department of Entomology, University of Arizona, Tucson 85721, USA
    J Econ Entomol 94:1237-42. 2001
    ....
  34. pmc Use of the Galleria mellonella caterpillar as a model host to study the role of the type III secretion system in Pseudomonas aeruginosa pathogenesis
    Sachiko Miyata
    Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA
    Infect Immun 71:2404-13. 2003
    ..mellonella model and the results of cytopathology assays performed with a mammalian tissue culture system validated the use of G. mellonella for the study of the P. aeruginosa TTSS...
  35. pmc The complete mitochondrial genome of the bag-shelter moth Ochrogaster lunifer (Lepidoptera, Notodontidae)
    Paola Salvato
    Department of Public Health, Comparative Pathology and Veterinary Hygiene, University of Padova, Agripolis, Viale dell Universita 16, 35020 Legnaro, Italy
    BMC Genomics 9:331. 2008
    ..Thus advance of lepidopteran mitogenomics deeply requires new genomes derived from a broad taxon sampling. In present work we describe the mitochondrial genome of the moth Ochrogaster lunifer...
  36. ncbi Identification of a gene associated with Bt resistance in Heliothis virescens
    L J Gahan
    Department of Biological Sciences, Clemson University, Clemson, SC 29634, USA
    Science 293:857-60. 2001
    ..Our findings enable efficient DNA-based screening for resistant heterozygotes by directly detecting the recessive allele...
  37. pmc New resistance mechanism in Helicoverpa armigera threatens transgenic crops expressing Bacillus thuringiensis Cry1Ac toxin
    Robin V Gunning
    New South Wales Department of Primary Industries, Tamworth, NSW, Australia 2340
    Appl Environ Microbiol 71:2558-63. 2005
    ..A resistance mechanism in which esterase sequesters Cry1Ac is proposed...
  38. ncbi Field-evolved resistance to Bt toxin Cry1Ac in the pink bollworm, Pectinophora gossypiella (Saunders) (Lepidoptera: Gelechiidae), from India
    Sanyasi Dhurua
    Division of Entomology, Indian Agricultural Research Institute, New Delhi, India
    Pest Manag Sci 67:898-903. 2011
    ..During the 2007-2008 and 2008-2009 seasons, pink bollworm populations in India were surveyed to evaluate their responses to Cry1Ac and seed powder containing Cry1Ac and Cry2Ab2...
  39. ncbi Within-plant signalling via volatiles overcomes vascular constraints on systemic signalling and primes responses against herbivores
    Christopher J Frost
    Center for Chemical Ecology, Pennsylvania State University, University Park, PA 16802, USA
    Ecol Lett 10:490-8. 2007
    ....
  40. pmc Superoxide production in Galleria mellonella hemocytes: identification of proteins homologous to the NADPH oxidase complex of human neutrophils
    David Bergin
    Medical Mycology Unit, National Institute of Cellular Biotechnology, Department of Biology, NUI Maynooth, Co Kildare, Ireland
    Infect Immun 73:4161-70. 2005
    ....
  41. ncbi Suppressing resistance to Bt cotton with sterile insect releases
    Bruce E Tabashnik
    Department of Entomology, University of Arizona, Tucson, Arizona, USA
    Nat Biotechnol 28:1304-7. 2010
    ..A multitactic eradication program that included the release of sterile moths reduced pink bollworm abundance by >99%, while eliminating insecticide sprays against this key invasive pest.
  42. ncbi An aerial-hawking bat uses stealth echolocation to counter moth hearing
    Holger R Goerlitz
    School of Biological Sciences, University of Bristol, Woodland Road, Bristol, UK
    Curr Biol 20:1568-72. 2010
    Ears evolved in many nocturnal insects, including some moths, to detect bat echolocation calls and evade capture [1, 2]...
  43. pmc Disruption of a cadherin gene associated with resistance to Cry1Ac {delta}-endotoxin of Bacillus thuringiensis in Helicoverpa armigera
    Xinjun Xu
    Department of Entomology, College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, People s Republic of China
    Appl Environ Microbiol 71:948-54. 2005
    ..thuringiensis resistance in field populations of lepidopteran pests...
  44. pmc Sex pheromone receptor specificity in the European corn borer moth, Ostrinia nubilalis
    Kevin W Wanner
    Department of Plant Sciences and Plant Pathology, Montana State University, Bozeman, Montana, USA
    PLoS ONE 5:e8685. 2010
    ..To further knowledge of the molecular mechanisms of pheromone detection and its evolution among closely related species we identified and characterized sex pheromone receptors from ECB(Z)...
  45. ncbi Genetic analysis of the xenobiotic resistance-associated ABC gene subfamilies of the Lepidoptera
    R Labbe
    Department of Biology, University of Western Ontario, London, ON, Canada
    Insect Mol Biol 20:243-56. 2011
    ..Taken together, these attributes of moth multidrug resistance-associated ABCs may confer distinct functional capacities to xenobiotic efflux...
  46. ncbi Odorant receptors from the light brown apple moth (Epiphyas postvittana) recognize important volatile compounds produced by plants
    Melissa D Jordan
    The Horticultural and Food Research Institute of New Zealand Limited HortResearch, Private Bag, Auckland, New Zealand
    Chem Senses 34:383-94. 2009
    b>Moths recognize a wide range of volatile compounds, which they use to locate mates, food sources, and oviposition sites...
  47. ncbi Northward migration of Helicoverpa armigera (Lepidoptera: Noctuidae) and other moths in early summer observed with radar in northern China
    Hong Qiang Feng
    Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100094, People s Republic of China
    J Econ Entomol 97:1874-83. 2004
    The northward migration of Helicoverpa armigera (Hübner) and other moths in early summer was observed with radar in 2001 and 2002 at Langfang, Hebei province, China. Migratory flights typically occurred at heights up to 1...
  48. ncbi Microsatellites reveal a lack of structure in Australian populations of the diamondback moth, Plutella xylostella (L.)
    N M Endersby
    Centre for Environmental Stress and Adaptation Research, School of Biological Sciences, Monash University, VIC 3800, Australia
    Mol Ecol 15:107-18. 2006
    ..We discuss these results with reference to insecticide resistance management strategies for P. xylostella in Australia...
  49. ncbi Cloning and expression of the cDNA encoding the FXPRL family of peptides and a functional analysis of their effect on breaking pupal diapause in Helicoverpa armigera
    Tian Yi Zhang
    Department of Molecular and Cell Biology, University of Science and Technology of China, Hefei 230027, China
    J Insect Physiol 50:25-33. 2004
    ..The high expression of this gene in pharate adults and adults indicates that the FXPRL family peptides may have multiple physiological functions...
  50. ncbi Allelic variation in a fatty-acyl reductase gene causes divergence in moth sex pheromones
    Jean Marc Lassance
    Department of Biology, Lund University, 22362 Lund, Sweden
    Nature 466:486-9. 2010
    ..In the sexual communication system of moths (Insecta: Lepidoptera), females emit a species-specific pheromone blend that attracts males over long distances...
  51. pmc Opposing plant community responses to warming with and without herbivores
    Eric Post
    Department of Biology, Penn State University, 208 Mueller Lab, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 105:12353-8. 2008
    ....
  52. ncbi RNA interference in the light brown apple moth, Epiphyas postvittana (Walker) induced by double-stranded RNA feeding
    C T Turner
    The Horticulture and Food Research Institute of New Zealand Ltd, Auckland, New Zealand
    Insect Mol Biol 15:383-91. 2006
    ..The potential mechanisms involved in the initiation, movement and amplification of the silencing signal are discussed...
  53. ncbi Developmental and insecticide-resistant insights from the de novo assembled transcriptome of the diamondback moth, Plutella xylostella
    Weiyi He
    Institute of Applied Ecology and Research Centre for Biodiversity and Eco Safety, Fujian Agriculture and Forestry University, Fuzhou, China
    Genomics 99:169-77. 2012
    ..The newly developed transcriptome will facilitate researches on the DBM developmental biology and insecticide resistance evolution, and ultimately provide better pest management systems...
  54. ncbi Gossypol-enhanced P450 gene pool contributes to cotton bollworm tolerance to a pyrethroid insecticide
    Xiao Yuan Tao
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China
    Mol Ecol 21:4371-85. 2012
    ....
  55. pmc Legionella pneumophila pathogenesis in the Galleria mellonella infection model
    Clare R Harding
    Centre for Molecular Microbiology and Infection, Division of Cell and Molecular Biology, Imperial College London, London, United Kingdom
    Infect Immun 80:2780-90. 2012
    ..Taken together, these results suggest that G. mellonella provides an effective model to investigate the interaction between L. pneumophila and the host...
  56. pmc Improvement of pest resistance in transgenic tobacco plants expressing dsRNA of an insect-associated gene EcR
    Jin Qi Zhu
    Key Laboratory of Insect Developmental and Evolutionary Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    PLoS ONE 7:e38572. 2012
    ..This study provides additional evidence that transgenic plant expressing dsRNA targeting insect-associated genes is able to improve pest resistance...
  57. ncbi Genetic architecture in codling moth populations: comparison between microsatellite and insecticide resistance markers
    P Franck
    UR1115 Plantes et Systèmes de culture Horticoles, INRA, F 84000 Avignon Cedex 9, France
    Mol Ecol 16:3554-64. 2007
    ..Differences in mutation-migration-drift equilibrium among treated and untreated orchards also suggest that insecticide applications are the main force regulating the local dynamics of codling moth populations...
  58. ncbi Engineering modified Bt toxins to counter insect resistance
    Mario Soberon
    Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Apartado Postal 510 3, Cuernavaca 62250, Morelos, Mexico
    Science 318:1640-2. 2007
    ..Our findings suggest that cadherin promotes Bt toxicity by facilitating toxin oligomerization and demonstrate that the modified Bt toxins may be useful against pests resistant to standard Bt toxins...
  59. pmc A comprehensive DNA barcode library for the looper moths (Lepidoptera: Geometridae) of British Columbia, Canada
    Jeremy R deWaard
    Department of Forest Sciences, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 6:e18290. 2011
    ..The looper moths of British Columbia (BC), Canada present a challenging case for species discrimination via DNA barcoding due to ..
  60. ncbi Functional and expression pattern analysis of chemosensory proteins expressed in antennae and pheromonal gland of Mamestra brassicae
    E Jacquin-Joly
    INRA, Unité de Phytopharmacie et des Médiateurs Chimiques, Bat A, Route de Saint Cyr, F 78026 Versailles Cedex, France
    Chem Senses 26:833-44. 2001
    ..This suggests that the M. brassicae CSP could be involved in transport of hydrophobic molecules through different aqueous media, such as the sensillar lymph, as well as the pheromonal gland cytosol...
  61. pmc Development of Galleria mellonella as an alternative infection model for the Burkholderia cepacia complex
    Kimberley D Seed
    Department of Biological Sciences, University of Alberta, Edmonton, Alberta T6G 2E9, Canada
    Infect Immun 76:1267-75. 2008
    ..For experimentation examining the virulent properties of the BCC, the wax worm has proven to be a useful alternative infection model...
  62. pmc The collagen-binding protein Cnm is required for Streptococcus mutans adherence to and intracellular invasion of human coronary artery endothelial cells
    Jacqueline Abranches
    Center for Oral Biology, University of Rochester Medical Center, Box 611, 601 Elmwood Ave, Rochester, NY 14642, USA
    Infect Immun 79:2277-84. 2011
    ..Thus, Cnm is required for S. mutans invasion of endothelial cells and possibly represents an important virulence factor of S. mutans that may contribute to cardiovascular infections and pathologies...
  63. ncbi Scanning the European corn borer (Ostrinia spp.) genome for adaptive divergence between host-affiliated sibling species
    Afiwa Midamegbe
    Institut National de la Recherche Agronomique, UMR CBGP INRA IRD Cirad Montpellier SupAgro, Campus International de Baillarguet, CS 30016, Montferrier sur Lez CEDEX, France
    Mol Ecol 20:1414-30. 2011
    ..A subset of 12 outlier loci were sequenced, of which 7 were successfully re-amplified as target candidate loci. Three of these showed homology with annotated lepidopteran sequences from public nucleotide databases...
  64. ncbi Identity and expression pattern of chemosensory proteins in Heliothis virescens (Lepidoptera, Noctuidae)
    J F Picimbon
    Institute of Physiology, University of Hohenheim, Garbenstrasse 30, 70593, Stuttgart, Germany
    Insect Biochem Mol Biol 31:1173-81. 2001
    ..The tissue distribution and the time course of appearance of HvirCSPs are in agreement with a possible role in contact chemosensation...
  65. pmc General principles of attraction and competitive attraction as revealed by large-cage studies of moths responding to sex pheromone
    J R Miller
    Department of Entomology, Michigan State University, East Lansing, MI 48824, USA
    Proc Natl Acad Sci U S A 107:22-7. 2010
    ..Major hypotheses are competitive attraction, desensitization, and camouflage. Working with codling moths, Cydia pomonella, in field cages millions of times larger than laboratory test tubes and at substrate ..
  66. pmc Long-term regional suppression of pink bollworm by Bacillus thuringiensis cotton
    Yves Carriere
    Department of Entomology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 100:1519-23. 2003
    ..The present findings suggest that long-term regional pest suppression after deployment of Bt crops may also contribute to reducing the need for insecticide sprays...
  67. pmc Frequency of resistance to Bacillus thuringiensis in field populations of pink bollworm
    B E Tabashnik
    Department of Entomology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 97:12980-4. 2000
    ..These results demonstrate that the assumptions and predictions of resistance management models must be reexamined...
  68. ncbi Complexity in specificities and expression of Helicoverpa armigera gut proteinases explains polyphagous nature of the insect pest
    A G Patankar
    Plant Molecular Biology Unit, Division of Biochemical Sciences, National Chemical Laboratory, 411 008, Pune, India
    Insect Biochem Mol Biol 31:453-64. 2001
    ..armigera gut and the flexibility in their expression during developmental stages and depending upon the diet provides a base for selection of proper PIs for insect resistance in transgenic crop plants...
  69. pmc Partial mitochondrial genome sequences of Ostrinia nubilalis and Ostrinia furnicalis
    Brad S Coates
    USDA ARS, Corn Insect and Crop Genetics Research Unit, Genetics Laboratory, c o Insectary, Iowa State University, Ames, Iowa, 50011
    Int J Biol Sci 1:13-8. 2005
    ..2%) compared to 2-fold degenerate codons (2.6%). These are the 3(rd) and 4(th) lepidopteran mitochondrial genome reference sequences in GenBank and useful for comparative mitochondrial studies...
  70. pmc Galleria mellonella as a model host to study infection by the Francisella tularensis live vaccine strain
    George Aperis
    Division of Infectious Diseases, Massachusetts General Hospital, Gray Jackson 504, 55 Fruit Street, Boston, MA 02114, USA
    Microbes Infect 9:729-34. 2007
    ..Delayed drug treatment reduced the efficacy of antibacterials and especially streptomycin. The G. mellonella-F. tularensis LVS system may facilitate the in vivo study of F. tularensis, efficacy with antibacterial agents...
  71. ncbi Gene identification and proteomic analysis of the esterases of the cotton bollworm, Helicoverpa armigera
    Mark G Teese
    CSIRO Entomology, GPO Box 1700, Canberra ACT 2601, Australia
    Insect Biochem Mol Biol 40:1-16. 2010
    ..Five of these sequences were matched to zones of activity on native PAGE at relative mobility values previously associated with insecticide resistance in this species...
  72. ncbi Molecular cloning, by a novel approach, of a cDNA encoding a putative olfactory protein in the labial palps of the moth Cactoblastis cactorum
    R Maleszka
    Visual Sciences, Research School of Biological Sciences, The Australian National University, Canberra, ACT
    Gene 202:39-43. 1997
    ..proteins including odorant-binding proteins (OBPs) in vertebrates and pheromone-binding proteins (PBPs) in moths. Although they share features common to OBPs and PBPs, such as the presence of signal peptides and cysteine motifs,..
  73. ncbi Functional characterization of pheromone receptors in the tobacco budworm Heliothis virescens
    G Wang
    State Key Laboratory for Biology of Plant Disease and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China
    Insect Mol Biol 20:125-33. 2011
    ..Based on our results and previous research we can now assign pheromone receptors in H. virescens males to each of the critical H. virescens agonistic pheromone compounds and two antagonistic compounds produced by heterospecific females...
  74. ncbi Odorant-binding-protein subfamilies associate with distinct classes of olfactory receptor neurons in insects
    R G Vogt
    Yale University School of Medicine, Section of Molecular Neurobiology, New Haven, Connecticut 06510
    J Neurobiol 22:74-84. 1991
    ..The association of different insect OBP subfamilies with distinct classes of olfactory neurons having different odorant specificities suggests that OBPs can act as selective signal filters, peripheral to the actual receptor proteins...
  75. ncbi Sex chromosomes and sex determination in Lepidoptera
    W Traut
    Universitat Lubeck, Zentrum fur Medizinische Strukturbiologie, Institut fur Biologie, Lubeck, Germany
    Sex Dev 1:332-46. 2007
    The speciose insect order Lepidoptera (moths and butterflies) and their closest relatives, Trichoptera (caddis flies), share a female-heterogametic sex chromosome system...
  76. ncbi Mining an Ostrinia nubilalis midgut expressed sequence tag (EST) library for candidate genes and single nucleotide polymorphisms (SNPs)
    B S Coates
    USDA ARS, Corn Insect and Crop Genetics Research Unit, Genetics Laboratory, Iowa State University, Ames, Iowa 50011, USA
    Insect Mol Biol 17:607-20. 2008
    ..This O. nubilalis larval midgut EST collection is a resource for gene discovery, expression information, and allelic variation for use in genetic marker development...
  77. pmc Behavioral consequences of innate preferences and olfactory learning in hawkmoth-flower interactions
    Jeffrey A Riffell
    Division of Neurobiology and Center for Insect Science, Arizona Research Laboratories, and Departments of Chemistry and Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 105:3404-9. 2008
    ..wrightii. Behavioral experiments with both naïve and experienced moths revealed that hawkmoths learn to feed from agave flowers through olfactory conditioning but readily switch to D...
  78. ncbi Gene flow among Cydia pomonella (Lepidoptera: Tortricidae) geographic and host populations in South Africa
    A E Timm
    Department of Entomology and Center for Agricultural Biodiversity, University of Stellenbosch, Matieland, South Africa
    J Econ Entomol 99:341-8. 2006
    ..pomonella populations may be limited and is explained in terms of limited moth flight, the relative isolation of pome fruit production areas, and the absence of wild hosts...
  79. pmc Linkage map of the peppered moth, Biston betularia (Lepidoptera, Geometridae): a model of industrial melanism
    A E Van't Hof
    Institute of Integrative Biology, University of Liverpool, UK
    Heredity (Edinb) 110:283-95. 2013
    ..Our study highlights the unusual evolutionary stability of lepidopteran autosomes; in contrast, higher rates of intrachromosomal rearrangements support a special role of the Z chromosome in adaptive evolution and speciation...
  80. ncbi Development and survival of the diamondback moth, Plutella xylostella (L.) (Lepidoptera: Yponomeutidae) as a function of temperature: effect on the number of generations in tropical and subtropical regions
    C A Marchioro
    Depto de Zoologia, Univ Federal do Paraná, Curitiba, PR, Brasil
    Neotrop Entomol 40:533-41. 2011
    ..xylostella is tolerant to a wide range of temperatures (6.1-32.5°C). Therefore, temperature cannot be considered a limiting factor for the occurrence of diamondback moth throughout the year in most regions of Brazil...
  81. pmc Neo-sex chromosomes and adaptive potential in tortricid pests
    Petr Nguyen
    Laboratory of Molecular Cytogenetics, Institute of Entomology, Biology Centre of the Academy of Sciences of the Czech Republic, 370 05 Ceske Budejovice, Czech Republic
    Proc Natl Acad Sci U S A 110:6931-6. 2013
    ..We suggest that this fusion significantly increased the adaptive potential of tortricid moths and thus contributed to their radiation and subsequent speciation.
  82. ncbi Properties of purified gut trypsin from Helicoverpa zea, adapted to proteinase inhibitors
    Mariateresa Volpicella
    Dipartimento di Biochimica e Biologia Molecolare, Universita di Bari, Italy
    Eur J Biochem 270:10-9. 2003
    ..The same inhibitors inhibited HzTrypsin-C with apparent equilibrium dissociation constants ranging from 1 nm to 30 nm. Thus, HzTrypsin-S seems to allow the insect to overcome different defensive proteinase inhibitors in plants...
  83. ncbi Comparative study of sex pheromone composition and biosynthesis in Helicoverpa armigera, H. assulta and their hybrid
    Hong lei Wang
    State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, China
    Insect Biochem Mol Biol 35:575-83. 2005
    ..armigera. The evolutionary relationships between the desaturases in several Helicoverpa species are also discussed in this paper...
  84. pmc Evolution of moth sex pheromones via ancestral genes
    Wendell L Roelofs
    Department of Entomology, Cornell University, Geneva, NY 14456, USA
    Proc Natl Acad Sci U S A 99:13621-6. 2002
    ..Their presence would allow for asymmetric tracking of male response to the new blend and, thus, evolution of an Ostrinia species with structurally different sex pheromone components...
  85. pmc Sialome of a generalist lepidopteran herbivore: identification of transcripts and proteins from Helicoverpa armigera labial salivary glands
    Maria de la Paz Celorio-Mancera
    Department of Entomology, Max Planck Institute for Chemical Ecology, Jena, Germany
    PLoS ONE 6:e26676. 2011
    ..This identification of secreted salivary gland proteins allows a more comprehensive understanding of insect feeding and poses new challenges for the elucidation of protein function...
  86. pmc Effect of nutrient deprivation on the susceptibility of Galleria mellonella larvae to infection
    Nessa Banville
    Department of Biology, National University of Ireland, Maynooth, Ireland
    Virulence 3:497-503. 2012
    ..Researchers utilizing these larvae should ensure adequate food is provided to larvae in order to allow valid comparisons to be made between results from different laboratories...
  87. ncbi Return migration of Helicoverpa armigera (Lepidoptera: Noctuidae) during autumn in northern China
    H Q Feng
    State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, People s Republic of China
    Bull Entomol Res 95:361-70. 2005
    ..The sudden increase in the proportion of H. armigera moths in the searchlight trap indicated migration into the area and catches increased 10-fold during the second half of ..
  88. ncbi The gp64 locus of Anticarsia gemmatalis multicapsid nucleopolyhedrovirus contains a 3' repair exonuclease homologue and lacks v-cath and ChiA genes
    Jeffrey M Slack
    Insect Biocontrol Laboratory, USDA, Beltsville, MD 20852, USA
    J Gen Virol 85:211-9. 2004
    ..AgMNPV differed from other group I NPVs in that ChiA and v-cath gene homologues were missing from the region downstream of the gp64 gene. Proteinase assays and genetic probes suggest the v-cath gene is absent from AgMNPV...
  89. pmc DNA barcodes reveal cryptic host-specificity within the presumed polyphagous members of a genus of parasitoid flies (Diptera: Tachinidae)
    M Alex Smith
    Biodiversity Institute of Ontario, University of Guelph, Guelph, ON, Canada N1G 2W1
    Proc Natl Acad Sci U S A 103:3657-62. 2006
    ..If general, these results will increase estimates of global species richness and imply that tropical conservation and host-parasite interactions may be more complex than expected...
  90. ncbi Beta-diversity of geometrid moths from northern Borneo: effects of habitat, time and space
    Jan Beck
    Kuala Belalong Field Studies Centre, Universiti Brunei Darussalem, Tungku Link, Gadong BE1410, Brunei
    J Anim Ecol 76:230-7. 2007
    ..5. Patterns of species turnover indicate no evidence for biotic homogenization due to human-caused degradation of habitats. Beta-diversity plays a crucial part in mediating the regional diversity of geometrids on Borneo...
  91. pmc Asymmetrical cross-resistance between Bacillus thuringiensis toxins Cry1Ac and Cry2Ab in pink bollworm
    Bruce E Tabashnik
    Department of Entomology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 106:11889-94. 2009
    ..Incorporating the potential effects of such cross-resistance in resistance management plans may help to sustain the efficacy of pyramided Bt crops...
  92. ncbi Genetic variability and genetic structure of wild and semi-domestic populations of tasar silkworm (Antheraea mylitta ) ecorace Daba as revealed through ISSR markers
    P K Kar
    Central Sericultural Germplasm Resources Centre, Central Silk Board, Thally Road, P B 44635109 Hosur, Tamil Nadu, India
    Genetica 125:173-83. 2005
    ..The high genetic variability present within wild Daba population of A. mylitta is of much importance for conservation as well as utilization in systematic breeding program...
  93. ncbi Potent virucidal activity in larval Heliothis virescens plasma against Helicoverpa zea single capsid nucleopolyhedrovirus
    Holly J R Popham
    USDA, Agricultural Research Service, Biological Control of Insects Research Laboratory, 1503 S Providence Road, Columbia, MO 65203, USA
    J Gen Virol 85:2255-61. 2004
    ..Thus, in the plasma of larval lepidopterans, the enzyme phenol oxidase may act as a constitutive, humoral innate antiviral immune response...
  94. ncbi Sound strategies: the 65-million-year-old battle between bats and insects
    William E Conner
    Department of Biology, Wake Forest University, Winston Salem, North Carolina 27106, USA
    Annu Rev Entomol 57:21-39. 2012
    The intimate details regarding the coevolution of bats and moths have been elucidated over the past 50 years...
  95. pmc SlyA is a transcriptional regulator involved in the virulence of Enterococcus faecalis
    Charlotte Michaux
    Laboratoire de Microbiologie de l Environnement, EA 956 soutenue par l INRA, IFR 146, Universite de Caen, 14032 Caen Cedex, France
    Infect Immun 79:2638-45. 2011
    ..In the mutant strain, 111 were underexpressed and 6 overexpressed, indicating that SlyA functions mainly as an activator of transcription...
  96. ncbi Mating-induced differential coding of plant odour and sex pheromone in a male moth
    Romina B Barrozo
    INRA, UMR 1272 Physiologie de l Insecte Signalisation et Communication, Route de St Cyr, 78000 Versailles, France
    Eur J Neurosci 33:1841-50. 2011
    ..the response patterns of pheromone-sensitive and plant volatile-sensitive neurons in virgin and mated male moths. By using intracellular recordings, we showed that mating changes the response characteristics of pheromone-..
  97. ncbi Insect larvae biofactories as a platform for influenza vaccine production
    E Gomez-Casado
    Department of Biotechnology, Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria INIA, Madrid, Spain
    Protein Expr Purif 79:35-43. 2011
    ....
  98. pmc Towards a global barcode library for Lymantria (Lepidoptera: Lymantriinae) tussock moths of biosecurity concern
    Jeremy R deWaard
    Forest Sciences, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 5:e14280. 2010
    ....
  99. ncbi Transcripts of the nicotinic acetylcholine receptor subunit gene Pxylα6 with premature stop codons are associated with spinosad resistance in diamondback moth, Plutella xylostella
    Frank D Rinkevich
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853 0901, USA
    Invert Neurosci 10:25-33. 2010
    ..Thus, it appears that spinosad resistance in diamondback moth is due to a mutation(s) that results in no functional Pxylα6 being produced...
  100. pmc Function of nuclear transport factor 2 and Ran in the 20E signal transduction pathway in the cotton bollworm, Helicoverpa armigera
    Hong Juan He
    School of Life Sciences, Key Laboratory of Plant Cell Engineering and Germplasm Innovation, Ministry of Education, Shandong University, Jinan 250100, Shandong, PR China
    BMC Cell Biol 11:1. 2010
    ..Nuclear transport factor 2 and small GTPase Ran participate in the nucleo-cytoplasm transport of macromolecules, but their function in the 20-hydroxyecdysone (20E) signal transduction pathway are not well known...
  101. ncbi A different repertoire of Galleria mellonella antimicrobial peptides in larvae challenged with bacteria and fungi
    Pawel Mak
    Department of Analytical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7 St, 30 387 Krakow, Poland
    Dev Comp Immunol 34:1129-36. 2010
    ..The Gram-negative bacterium and filamentous fungus were particularly effective immunogens, especially affecting the levels of lysozyme, Galleria defensin, proline-rich peptide 2 and cecropin D-like peptide...

Research Grants53

  1. Circadian Clock: Differential Cryptochrome Functions
    Steven M Reppert; Fiscal Year: 2011
    ..properties of the CRY proteins by defining distinct CRY mechanisms of action in lepidopterans (butterflies and moths) using molecular, biochemical, genetic, and behavioral approaches...
  2. Mosquitocidal Action of Bacillus thuringensis Toxins
    Sarjeet S Gill; Fiscal Year: 2013
    ..This implies both APN and ALP of mosquitoes could act as primary rather than as secondary receptors as in moths, suggesting a possible difference in the mode of action of mosquitocidal and lepidopteran Cry toxins...
  3. Convergent Molecular Evolution of Moth and Spider Silks
    NADIA AYOUB; Fiscal Year: 2009
    ..With an initial focus on spiders and moths, the databases and analytical methods developed here will lay the groundwork for future comparative work on ..
  4. TRANSGENIC MICE, AGING, CANCER, AND OXIDATIVE DAMAGE
    Arlan Richardson; Fiscal Year: 2001
    ..4. To measure parameters of mitochondrial function (e.g., mitochondrial respiration, hydrogen peroxide generation, and permeability transition) in tissues of wild type, Sod2+/-, and Sod2+/-XGpx1+/-F1 mice at 5, 14 and 26 moths of age.
  5. Vitamins, Breast Milk HIV Shedding and Child Health
    Eduardo Villamor; Fiscal Year: 2006
    ..effect of vitamin supplements on the concentration of vitamins A, B12, and E in breast milk at delivery, 3, and 6 moths thereafter, and the associations between the concentration of these vitamins in breast milk and child morbidity ..
  6. MOLECULAR PHYSIOLOGY OF THE EPITRACHEAL ENDOCRINE SYSTEM
    Michael Adams; Fiscal Year: 2002
    ..We have identified ecdysis-triggering hormones (ETHs) in flies (Drosophila, Musca) and moths (Manduca, Bombyx), demonstrated their functional roles in regulating in the ecdysis sequence, and established that ..
  7. MOLECULAR STUDIES OF A MAMMALIAN PHEROMONE
    L Rasmussen; Fiscal Year: 2000
    ..This system has the distinct advantages that Z7-12:Ac is a well-characterized sex pheromone in moths and a proven photolabeled analog is available, the quantitative bioassay is robust, the emitter source (..
  8. DOWN SYNDROME CHILDREN--EARLY COMMUNICATIVE DEVELOPMENT
    CAROLYN MERVIS; Fiscal Year: 1992
    ..Down syndrome will be followed for 31 months; dyads involve normally developing infants will participate for 19 moths, by which time all children should have begun to produce language referentially...
  9. GROWTH FAILURE IN CHILDREN WITH RENAL DISEASES
    James Chan; Fiscal Year: 1991
    ..However, 11 of the study exits have completed 6 moths of control and 6 months of treatment data collection; thus, 78 patients have completed the minimal periods of the ..
  10. NEUROBIOLOGY OF ALCOHOL CUE-INDUCED CRAVING
    Ismene Petrakis; Fiscal Year: 1999
    ..Methods: In an ongoing study, individuals meeting DSM-IV criteria for alcohol will be recruited, 1-3 moths post-detoxification. Patients will complete an initial alcohol cue exposure session...
  11. EMOTION REGULATION AND EARLY BEHAVIOR PROBLEMS
    Cynthia Stifter; Fiscal Year: 2004
    ..recruited and tested since they were 2 weeks of age, and their parents through the preschool years until 6 moths into their first grade experience, a period when the social contexts of the child expand and study examining the ..
  12. Olfactory development in moths: a novel system for studying pattern formation, ce
    KRISTY KENYON; Fiscal Year: 2009
    ..The model organisms that the investigators propose to use in this study are heliothine moths in the genus Heliothis and Heliocoverpa (family Noctuidae)...
  13. CHARACTERIZATION OF INSECT OOCYTE MRNA
    SPENCER BERRY; Fiscal Year: 1980
    ..of maternal messenger RNA-protein complexes (mRNP) during oogenesis and embryogenesis of certain large moths. Ultracentrifugation, affinity chromatography, and electrophoresis are used to isolate, analyze, and characterize ..
  14. Analysis of combinatorial olfactory coding
    Kevin Daly; Fiscal Year: 2004
    ..Aim 2 further develops Aim 1 by looking at how the relatedness of these overlapping spatiotemporal odor codes changes as moths are conditioned to related odors to food.
  15. DISCRIMINATION OF COMPLEX MIXTURE IN 0LFACTORY SIGNALING
    Charles Linn; Fiscal Year: 2000
    ..sex pheromone-processing pathways in the male-specific macroglomerular complex (MGC) of the antennal lobe of male moths. Olfactory glomeruli in the MGC are critically involved in the spatial organization of sensory axons for specific ..
  16. MBRS SCORE PROGRAM AT TOUGALOO
    Asoka Srinivasan; Fiscal Year: 2002
    ..This will be a continuation of his current project investigating the neuroendocrine control of reproduction in moths. This proposal also includes a pilot project. Dr...
  17. Population genetics of transgenes in mosquito vectors
    Fred Gould; Fiscal Year: 2008
    ..A user-friendly form of the models as well as an accessible manual will be developed and placed on the internet. ..
  18. C.elegans as a model system forC.neoformans pathogenesis
    Eleftherios Mylonakis; Fiscal Year: 2007
    ..Because C. neoformanshas similarities with other pathogenic yeasts, we expect that our findings will facilitate the study of fungus/host interaction in general. ..
  19. A C.elegans high-throughput assay for the identification of new antifungal agents
    Eleftherios Mylonakis; Fiscal Year: 2010
    ....
  20. Catalytic definition of insecticide-metabolizing P450s
    MARY SCHULER; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  21. PARVOVIRUS STRUCTURE, CAPSID ASSEMBLY, AND RECEPTORS
    Colin Parrish; Fiscal Year: 2007
    ..abstract_text> ..
  22. Extracellular Proteins in Virulence of B. (pseudo)mallei
    Mark Schell; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  23. Antigenic structure of adeno-associated virus capsids and antibody escape mutants
    Colin Parrish; Fiscal Year: 2008
    ..In this study we seek to define the antigenic structures if the viruses so that the adverse effects of antibodies on gene therapy trials can be better understood, and perhaps avoided in the future. [unreadable] [unreadable] [unreadable]..
  24. Linking Breast Cancer Advocacy and Environmental Justice
    Julia Brody; Fiscal Year: 2008
    ....
  25. CRCNS: Automated Behavior Analysis for Model Genetic Organism
    Michael H Dickinson; Fiscal Year: 2010
    ..Like the robotic sequencers that revolutionized the study of genomics, these devices will help transform behavioral science into a modern discipline of Ethometrics. ..
  26. PHYLOGENY AND ONTOGENY OF AN AUDITORY SYSTEM
    DAVID YAGER; Fiscal Year: 2004
    ..This line of research will lead to a clearer understanding of the neural and non-neural characteristics that define a hot spot for auditory system evolution. ..
  27. TGF-beta superfamily in neonatal obstructive nephropathy and recovery
    Robert L Chevalier; Fiscal Year: 2010
    ..A new animal (mouse) model is proposed to study the major cellular mechanisms for injury to the newborn kidney, as well as to evaluate new therapies to enhance recovery. ..
  28. Integrated Theoretical and Experimental Studies of P450 Structure and Function
    Mary A Schuler; Fiscal Year: 2010
    ....
  29. Mosquito Immunity to Alphaviruses
    Brian Foy; Fiscal Year: 2006
    ..3) Characterize the mechanisms that Culex tritaeniorhynchus mosquitoes use to clear Sindbis virus-infected midgut cells. [unreadable] [unreadable]..
  30. Impact of Environmental Pollutants on Breast Cancer and*
    Julia Brody; Fiscal Year: 2005
    ..abstract_text> ..
  31. Marker development for mosquito hemocytes
    MICHAEL STRAND; Fiscal Year: 2006
    ..The results of this study will provide essential tools for understanding the role of different hemocytes in cellular immunity of An. gambiae and likely other species of mosquitoes. ..
  32. Recombination and meiotic progression in the mouse
    Laura Reinholdt; Fiscal Year: 2004
    ..Finally, a new, potentially meiotic mutation, Mei5, which may cause a meiotic defect that escapes detection by meiotic checkpoint mechanisms, will be phenotypically characterized and genetically mapped. ..
  33. Viral DNA Replication and Late Transcription
    Linda Guarino; Fiscal Year: 2004
    ..Knowledge gained from these experiments should be relevant to other viral systems and will provide a better understanding of the complex interactions between transcription and replication machinery in eukaryotic cells. ..
  34. DISRUPTION OF HOST IMMUNE RESPONSE BY A PARASITIC WASP
    MICHAEL STRAND; Fiscal Year: 2001
    ..Hemocyte effector functions are conserved across invertebrate taxa. What we learn in this study will provide important comparative information on the factors regulating anti-parasitic and anti-viral defenses in arthropods. ..
  35. Risk Factors for Ductal Carcinoma In Situ (DCIS)
    Julia Brody; Fiscal Year: 2004
    ..The study builds on the Cape Cod Breast Cancer and Environment Study of invasive breast cancer and additional grants that currently support the proposed study of DCIS. ..
  36. PREDOCTORAL FELLOWSHIPS FOR STUDENTS WITH DISABILITIES
    SARA OPPENHEIM; Fiscal Year: 2004
    ..abstract_text> ..
  37. Conference: Progress and Issues in Olfactory Development
    Lynne Oland; Fiscal Year: 2002
    ..Several delegates whose primary research areas lie in other sensory systems but whose interests lie in related developmental questions also will be invited. ..
  38. CELLULAR DEFENSE RESPONSE IN AN INSECT SYSTEM
    MICHAEL STRAND; Fiscal Year: 2005
    ....
  39. Fetal Programming Fructose and Insulin Resistance
    SHAWN DONKIN; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  40. COMPLEX MIXTURE DISCRIMINATION IN OLFACTORY SIGNALING
    Charles Linn; Fiscal Year: 2003
    ..sex pheromone-processing pathways in the male-specific macroglomerular complex (MGC) of the antennal lobe of male moths. Olfactory glomeruli in the MGC are critically involved in the spatial organization of sensory axons for specific ..
  41. REGULATION OF JUVENILE HORMONE SYNTHESIS
    Barbara Stay; Fiscal Year: 2003
    ....
  42. MECHANISMS OF PARVOVIRUS INFECTION AND HOST RANGE
    Colin R Parrish; Fiscal Year: 2011
    ..We would seek to complement endosomal escape mutants in trans by adding adenovirus capsids, competent wild type parvovirus, or transferrin-PEI conjugates to the cells along with the parvoviruses. ..
  43. Dynamically Crosslinked Hydrogels
    Russell Stewart; Fiscal Year: 2006
    ..These novel hydrogels may find wide ranging biomedical applications in drug delivery, as active surface coatings or microactuators in medical devices. ..
  44. Self-immobilizing Proteins
    Russell Stewart; Fiscal Year: 2005
    ..The widely expected future impact of protein arrays on clinical diagnosis and other areas of human health care may be realized more quickly with new and effective protein modification technology. ..
  45. CATALYTIC SITE IN FURANOCOUMARIN-METABOLIC P450S
    MARY SCHULER; Fiscal Year: 2002
    ....
  46. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin L Hughes; Fiscal Year: 2010
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
  47. Gene Duplication and Genome Evolution
    Austin Hughes; Fiscal Year: 2004
    ..5) Examining the role of transposable elements in duplication of genomic segments by testing for nonrandom association between these elements and putatively duplicated blocks in the yeast genome. ..
  48. Intercellular Signaling in Obstructive Nephropathy
    ROBERT CHEVALIER; Fiscal Year: 2005
    ..This will lead to improved outcomes in adulthood. ..
  49. RECEPTORS FROM MOSQUITO AEDES AEGYPTI EXCRETORY SYSTEM
    PATRICIA PIETRANTONIO; Fiscal Year: 2002
    ..Aegypti. To test the hypothesis, the applicant proposes to clone the receptor gene, localize the tissue expression by in situ hybridization and immunohistochemistry and express the protein in transformed cells. ..
  50. Functional Characterization of Drosophila Odor Receptors
    ELISSA HALLEM; Fiscal Year: 2005
    ..The contribution of individual odor receptors to receptor neuron response properties will be examined, thus furthering our understanding of both olfactory coding and the molecular basis of odor-receptor interactions. ..