Genomes and Genes
Summary: Parasitic, blood-sucking, wingless insects comprising the order Siphonaptera.
Publications306 found, 100 shown here
- Prevalence and abundance of fleas in black-tailed prairie dog burrows: implications for the transmission of plague (Yersinia pestis)Dan J Salkeld
IUCN The World Conservation Union, NW, Washington, DC 20009, USA
J Parasitol 94:616-21. 2008..Epizootics, or die-offs, in prairie dogs (Cynomys ludovicianus) occur sporadically and fleas (Siphonaptera) are probably important in the disease's transmission and possibly as maintenance hosts of Y...
- Yersinia pestis--etiologic agent of plagueR D Perry
Department of Microbiology and Immunology, University of Kentucky, Lexington 40536, USA
Clin Microbiol Rev 10:35-66. 1997..Disappearance of the disease is unlikely due to the wide range of mammalian hosts and their attendant fleas. The flea/rodent life cycle of Y...
- Age-biased parasitism and density-dependent distribution of fleas (Siphonaptera) on a desert rodentH Hawlena
Department of Life Sciences and Ramon Science Center, Jacob Blaustein Institutes for Desert Research, Ben Gurion University of the Negev, Beer Sheva, 84105, Israel
Oecologia 146:200-8. 2005..We tested two alternative hypotheses about host preference by fleas in relation to the age of their rodent host...
- Evolution of host specificity in fleas: is it directional and irreversible?Robert Poulin
Department of Zoology, University of Otago, P O Box 56, Dunedin, New Zealand
Int J Parasitol 36:185-91. 2006..in the evolution of host specificity using a large data set and phylogenetic information on 297 species of fleas parasitic on small mammals...
- Identifying risk factors for tungiasis and heavy infestation in a resource-poor community in northeast BrazilMarion Muehlen
Department of Medical Microbiology, Institute of Infectious Medicine, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
Trans R Soc Trop Med Hyg 100:371-80. 2006Tungiasis is a neglected parasitic skin disease caused by penetration of female sand fleas into the epidermis. The ectoparasitosis is widespread in resource-poor communities in South America, the Caribbean and sub-Saharan Africa...
- The abundance threshold for plague as a critical percolation phenomenonS Davis
Theoretical Epidemiology, Faculty of Veterinary Medicine, University of Utrecht, Yalelaan 7, 3584 CL Utrecht, The Netherlands
Nature 454:634-7. 2008..a percolation threshold, which arises from the difference in scale between the movements that transport infectious fleas between family groups and the vast size of contiguous landscapes colonized by gerbils...
- Flea-borne rickettsioses: ecologic considerationsA F Azad
Department of Microbiology and Immunobiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Emerg Infect Dis 3:319-27. 1997..g., free-ranging cats, dogs, and opossums and their fleas. In addition to the vector-host components of the murine typhus cycle, we have uncovered a second typhuslike ..
- The Yersinia pestis caf1M1A1 fimbrial capsule operon promotes transmission by flea bite in a mouse model of bubonic plagueFlorent Sebbane
Institut National de la Sante et de la Recherche Medicale, U801, Institut Pasteur de Lille, Lille, France
Infect Immun 77:1222-9. 2009Plague is a zoonosis transmitted by fleas and caused by the gram-negative bacterium Yersinia pestis. During infection, the plasmidic caf1M1A1 operon that encodes the Y...
- The animal reservoir of Tunga penetrans in severely affected communities of north-east BrazilJ Heukelbach
Department of Community Health, School of Medicine, Federal University of Ceara, Fortaleza, Brazil
Med Vet Entomol 18:329-35. 2004..5) in the fishing village. High prevalence rates (range 31-67%) of tungiasis in humans, pets and rats (but apparently not other animals) indicate the need for an eco-epidemiological approach to control of this anthropo-zoonotic problem...
- Analysis of Yersinia pestis gene expression in the flea vectorViveka Vadyvaloo
Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institutes of Health, USA
Adv Exp Med Biol 603:192-200. 2007..This article serves as a review of known factors involved in flea-borne transmission and introduces an 'in vivo' microarray approach to elucidating the genetic basis of Y. pestis infection of- and transmission by the flea...
- Identification of gmhA, a Yersinia pestis gene required for flea blockage, by using a Caenorhabditis elegans biofilm systemCreg Darby
Department of Microbiology, University of Alabama at Birmingham, 1530 3rd Avenue S, BBRB Box 19, Birmingham, AL 35294 2170, USA
Infect Immun 73:7236-42. 2005..elegans biofilm formation and for flea blockage but only moderately defective in an in vitro biofilm assay. These results validate use of the C. elegans biofilm system to identify genes and pathways involved in Y. pestis flea blockage...
- Trypanosomes, fleas and field voles: ecological dynamics of a host-vector--parasite interactionA Smith
Population Biology Research Group, School of Biological Sciences, Biosciences Building, University of Liverpool, Liverpool L69 7ZB, UK
Parasitology 131:355-65. 2005..Overall, males of all sizes and ages were more likely to be infested with fleas than their female counterparts...
- Predictive thresholds for plague in KazakhstanStephen Davis
Danish Pest Infestation Laboratory, Skovbrynet 14, DK 2800 Kongens Lyngby, Denmark
Science 304:736-8. 2004..We parameterized predictive models that should reduce the costs of plague surveillance in central Asia and thereby encourage its continuance...
- The biology, ecology, and management of the cat fleaM K Rust
Department of Entomology, University of California at Riverside 92521 0314, USA
Annu Rev Entomol 42:451-73. 1997..In recent years, the control of cat fleas has increasingly relied on the use of IGRs applied to the host or to the indoor environment...
- Comparative speed of kill of selamectin, imidacloprid, and fipronil-(S)-methoprene spot-on formulations against fleas on catsM W Dryden
Department of Diagnostic Medicine Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA
Vet Ther 6:228-36. 2005..Following initial application only imidacloprid had caused a significant reduction in adult fleas on treated cats within 6 hours, but by 24 hours all three formulations had killed 96.7% of the fleas...
- Ectoparasitic "jacks-of-all-trades": relationship between abundance and host specificity in fleas (Siphonaptera) parasitic on small mammalsBoris R Krasnov
Ramon Science Center and Mitrani Department of Desert Ecology, Jacob Blaustein Institute for Desert Research, Ben Gurion University of the Negev, P O Box 194, Mizpe Ramon 80600, Israel
Am Nat 164:506-16. 2004..We test these alternative hypotheses with data on host specificity and abundance of fleas parasitic on small mammals from 20 different regions...
- [Fleas community in introduced Siberian chipmunks (Tamias sibiricus Laxmann) in Forest of Sénart, France]B Pisanu
Museum national d histoire naturelle, Département Ecologie et Gestion de la Biodiversité, UMR 5173 MNHN CNRS P6, 61, rue Buffon, F 75005 Paris, France
Parasite 15:35-43. 2008We examined the fleas community in an introduced population of Siberian chipmunks, Tamias sibiricus, between 2005 and 2007, in the Forest of Sénart (Essonne, France)...
- Efficacy of selamectin and fipronil-(S)-methoprene spot-on formulations applied to cats against adult cat fleas (Ctenocephalides felis), flea eggs, and adult flea emergenceMichael Dryden
Department of Diagnostic Medicine Pathology, Colleg of Veterinary Medicine, Kansas State University, Manhattan 66503, USA
Vet Ther 8:255-62. 2007A study was conducted to evaluate the efficacy of selamectin and fipronil-(S)-methoprene against adult cat fleas (Ctenocephalides felis), flea egg production, and the viability of flea eggs collected from treated cats...
- Identification, cloning, and characterization of a major cat flea salivary allergen (Cte f 1)M J McDermott
Heska Corporation, 1613 Prospect Parkway, Fort Collins, CO 80525, USA
Mol Immunol 37:361-75. 2000..Competition ELISA demonstrated that approximately 90% of the specific IgE binding to native Cte f 1 could be blocked by the different forms of rCte f 1...
- Characterization of late acyltransferase genes of Yersinia pestis and their role in temperature-dependent lipid A variationRoberto Rebeil
Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 S 4th St, Hamilton, Montana 59840, USA
J Bacteriol 188:1381-8. 2006..This mutant was able to infect and block fleas as well as the parental wild-type strain, indicating that the low-temperature-dependent change to hexa-acylated ..
- Loss of a biofilm-inhibiting glycosyl hydrolase during the emergence of Yersinia pestisDavid L Erickson
Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA
J Bacteriol 190:8163-70. 2008..pestis to produce biofilm in the flea foregut. Mutational loss of this glycosidase activity in Y. pestis may have contributed to the recent evolution of flea-borne transmission...
- Evaluation of the effects of selamectin against adult and immature stages of fleas (Ctenocephalides felis felis) on dogs and catsT L McTier
Animal Health Clinical Affairs, Central Research Division, Pfizer Inc, Groton, CT 06340, USA
Vet Parasitol 91:201-12. 2000..study was in dogs and the other in cats, and each animal was infested with approximately 100 unfed viable adult fleas prior to treatment...
- Parasites of domestic and wild animals in South Africa. XLIV. Fleas (Insecta: Siphonaptera: Pulicidae) collected from 15 carnivore speciesI G Horak
Department of Zoology and Entomology, University of the Free State, PO Box 339, Bioemfontein, 9300 South Africa
Onderstepoort J Vet Res 71:9-14. 2004b>Fleas were collected from 61 wild carnivores belonging to 13 species in various nature reserves and on farms, two feral domestic cats in a nature reserve and a domestic dog in the city of Johannesburg...
- Estimation of vector infectivity rates for plague by means of a standard curve-based competitive polymerase chain reaction method to quantify Yersinia pestis in fleasB J Hinnebusch
Laboratory of Microbial Structure and Function, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA
Am J Trop Med Hyg 58:562-9. 1998..large numbers of Yersinia pestis within a bacterial mass that blocks the flea's foregut, and only such blocked fleas are important for biologic transmission...
- Molecular evidence for Bartonella spp. in cat and dog fleas from Germany and FranceF T Just
Institute for Comparative Tropical Medicine and Parasitology, Veterinary Faculty, Ludwig Maximilians University Munich, Germany
Zoonoses Public Health 55:514-20. 2008Nine hundred and fifty-two fleas were collected from 148 cats and 133 dogs at 18 widely distributed geographic locations in Germany and France and examined for the presence of six different Bartonella spp...
- Medicinal plant treatments for fleas and ear problems of cats and dogs in British Columbia, CanadaCheryl Lans
DVM, P O Box 72045, Sasamat, Vancouver, BC V6R4P2, Canada
Parasitol Res 103:889-98. 2008..This paper reports on the medicinal plants used for fleas in cats and dogs. Fleas and flies are treated with Artemisia vulgaris L. (Asteraceae), Citrus x limon (L...
- Tungiasis in rural Haiti: a community-based responseJ Keith Joseph
Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, 1620 Tremont Street, 3rd Floor, Boston, MA 02120, USA
Trans R Soc Trop Med Hyg 100:970-4. 2006..workers cleaned and disinfected patients' feet and any parts of the body with ectopic lesions, and then extracted fleas from existing lesions. Patients with superinfections were treated with appropriate antibiotics...
- Plague and the human flea, TanzaniaAnne Laudisoit
University of Antwerp, Antwerp, Belgium
Emerg Infect Dis 13:687-93. 2007Domestic fleas were collected in 12 villages in the western Usambara Mountains in Tanzania...
- Insecticide susceptibilities of cat fleas (Siphonaptera: Pulicidae) from several regions of the United StatesRobert L Bossard
Department of Entomology, Kansas State University, Manhattan 66506, USA
J Med Entomol 39:742-6. 2002..Varying susceptibility of cat fleas may affect control success.
- Emended description of Rickettsia felis (Bouyer et al. 2001), a temperature-dependent cultured bacteriumBernard La Scola
Unite des Rickettsies, CNRS UPRESA 6020, Faculte de Medecine, Universite de la Mediterranee, 27 Bd Jean Moulin, 13385 Marseille 05, France
Int J Syst Evol Microbiol 52:2035-41. 2002..recognized rickettsial species, is genotypically indistinguishable from bacteria previously detected within cat fleas and provisionally named ELB. Comparison of the phenotypic characteristics previously described for R...
- Investigations on the biology, epidemiology, pathology and control of Tunga penetrans in Brazil: IV. Clinical and histopathologyHermann Feldmeier
Department of Medical Microbiology and Immunology of Infection, Institute for Infection Medicine, Charite University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 27, 12203 Berlin, Germany
Parasitol Res 94:275-282. 2004..related to the number of lesions, and the total number of parasites present correlated with the number of fleas occurring in clusters...
- Investigations on the biology, epidemiology, pathology and control of Tunga penetrans in Brazil: I. Natural history of tungiasis in manMargit Eisele
Institute of International Health, Center for Humanities and Health Sciences, Faculty of Medicine, Free University of Berlin, Fabeckstrasse 60 62, 12203, Berlin, Germany
Parasitol Res 90:87-99. 2003..It allows a more precise diagnosis, enables the assessment of chemotherapeutic approaches and helps to evaluate control measures at the community level...
- Development of a larval bioassay for susceptibility of cat fleas (Siphonaptera: Pulicidae) to imidaclopridM K Rust
Department of Entomology, University of California, Riverside 92521 0314, USA
J Med Entomol 39:671-4. 2002Strategies for controlling cat fleas, Ctenocephalidesfelisfelis (Bouché), have undergone dramatic changes in the past 5 yr...
- Prevalence of Bartonella species, haemoplasma species, Ehrlichia species, Anaplasma phagocytophilum, and Neorickettsia risticii DNA in the blood of cats and their fleas in the United StatesMichael R Lappin
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, 80523, USA
J Feline Med Surg 8:85-90. 2006Ctenocephalides felis were killed and collected from 92 cats in Alabama, Maryland, and Texas. The fleas and blood from the corresponding cat were digested and assessed in polymerase chain reaction assays that amplify DNA of Ehrlichia ..
- Transmission efficiency of two flea species (Oropsylla tuberculata cynomuris and Oropsylla hirsuta) involved in plague epizootics among prairie dogsAryn P Wilder
Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80522, USA
Ecohealth 5:205-12. 2008..pestis, is an exotic disease in North America circulating predominantly in wild populations of rodents and their fleas. Black-tailed prairie dogs (Cynomys ludovicianus) are highly susceptible to infection, often experiencing ..
- Rickettsia felis in Ctenocephalides spp. fleas, BrazilRiva P Oliveira
Departamento de Nutrição Clínica e Social, Escola de Nutrição, Universidade Federal de Ouro Preto, Campus Morro do Cruzeiro, Ouro Preto Minas Gerais State, Brazil CEP 34 500 000
Emerg Infect Dis 8:317-9. 2002..Pooled fleas collected near two fatal cases contained rickettsial DNA...
- Poor vector competence of fleas and the evolution of hypervirulence in Yersinia pestisEllen A Lorange
Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA
J Infect Dis 191:1907-12. 2005..The poor vector competence of fleas likely imposed selective pressure that favored the emergence and continued maintenance of a hypervirulent Y...
- Tunga penetrans: molecular identification of Wolbachia endobacteria and their recognition by antibodies against proteins of endobacteria from filarial parasitesPeter Fischer
Department of Helminthology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
Exp Parasitol 102:201-11. 2002..Ultrastructural studies showed that Wolbachia are abundant in the ovaries of neosomic fleas, whereas other, smaller and morphologically distinct, bacteria were observed in the lumen of the intestine...
- Role of Yersinia murine toxin in survival of Yersinia pestis in the midgut of the flea vectorB Joseph Hinnebusch
Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
Science 296:733-5. 2002..pestis from a cytotoxic digestion product of blood plasma in the flea gut. By enabling colonization of the flea midgut, acquisition of this PLD may have precipitated the transition of Y. pestis to obligate arthropod-borne transmission...
- Control of fleas on naturally infested dogs and cats and in private residences with topical spot applications of fipronil or imidaclopridM W Dryden
Department of Diagnostic Medicine Pathobiology, 1800 Denison Avenue, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA
Vet Parasitol 93:69-75. 2000..5 and 96.5%, respectively. In addition, flea numbers in the in-home environment were reduced by 99. 0 and 98.6% in homes, where pets were treated with imidacloprid or fipronil, respectively...
- Association of Bartonella with the fleas (Siphonaptera) of rodents and bats using molecular techniquesWill K Reeves
Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS G 13, Atlanta, GA 30333, USA
J Vector Ecol 32:118-22. 2007Bartonella spp. are putatively vector-borne bacterial agents of humans and animals. Fleas have been incriminated as vectors of Bartonella spp...
- Flea, rodent, and plague ecology at Chuchupate Campground, Ventura County, CaliforniaRichard M Davis
Vector Borne Disease Section, California Department of Health Services, Ventura 93003, USA
J Vector Ecol 27:107-27. 2002..in Ventura County, California, was closed to the public for 18 years (1982 to 2000) because of uncontrolled vector fleas and persistent plague antibody titers in rodents...
- [Two new fleas (Siphonaptera: Rhopalopsyllidae: Parapsyllinae) of Argentina, from Abrocoma uspallata Braun and Mares, 2002, (Rodentia: Abrocomidae)]J C Beaucournu
Laboratoire de Parasitologie et Zoologie appliquée, Faculte de Medecine, Rennes, France
Parasite 12:39-43. 2005..Ectinorus (E.) uspallatae n. sp. and Delostichus ojedai n. sp. are described from the rodent Abrocomid, Abrocoma uspallata Braun and Mares, 2002, a new small mammal of Argentina...
- Effects of the removal of large herbivores on fleas of small mammalsDouglas J McCauley
Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA
J Vector Ecol 33:263-8. 2008..To make this determination, we experimentally excluded large herbivores and measured the number of fleas present on the numerically dominant small mammal, the pouched mouse, Saccostomus mearnsi...
- Bacterial superinfection in human tungiasisH Feldmeier
Institute of Social Medicine, Center for Humanities and Health Sciences, Faculty of Medicine, Free University of Berlin, Germany
Trop Med Int Health 7:559-64. 2002..To prevent spreading of pathogens to the surrounding tissue and/or the systemic circulation, sand fleas should be surgically extracted immediately after penetration.
- Characterization of spotted fever group rickettsiae in flea and tick specimens from northern PeruPatrick J Blair
U S Naval Medical Research Center Detachment, Lima, Peru
J Clin Microbiol 42:4961-7. 2004..Amplification and sequencing of portions of the htrA and ompA genes in pooled samples (2 of 59) taken from fleas identified the pathogen Rickettsia felis. Four tick samples yielded molecular evidence of SFG rickettsiae...
- [Two new species of fleas from Chile and Argentina(Insecta-Siphonaptera: Stephanocircidae and Rhopalopsyllidae) and raising of a new sub-genus of Plocopsylla Jordan, 1931]J C Beaucournu
Laboratoire de Parasitologie, Faculte de Medecine, avenue du professeur Leon Bernard, F 35043 Rennes Cedex, France
Parasite 11:249-52. 2004..is raised, Schrammapsylla Beaucournu and Ménier from the entire group B of Schramm & Lewis, 1988 and two new fleas from Chile and Argentina are described: Plocopsylla (S.) muruai n. sp. Beaucournu and Gallardo and Ectinorus (E...
- Tungiasis among five communities in south-western Trinidad, West IndiesD D Chadee
Insect Vector Control Division, Ministry of Health, St Joseph, Trinidad
Ann Trop Med Parasitol 92:107-13. 1998..012), with mean (S.D.) burdens of 5.44 (2.54) fleas/male infected subject and 2.38 (2.00) fleas/female infected subject...
- High prevalence of tungiasis in a poor neighbourhood in Fortaleza, Northeast BrazilThomas Wilcke
Institute of Social Medicine, Centre for Humanities and Health Sciences, Faculty of Medicine, Free University of Berlin, Fabeckstrasse 60 62, Germany
Acta Trop 83:255-8. 2002..As the favela is typical for the many poor communities in northeast Brazil, it can be assumed that tungiasis is a frequent infection in the underprivileged in this part of the country...
- A review of plague persistence with special emphasis on fleasJeffrey Wimsatt
Center for Comparative Medicine and Department of Biology, University of Virginia, Charlottesville, USA
J Vector Borne Dis 46:85-99. 2009..A second phase (enzootic plague) ensues when plague is difficult to detect from fleas, hosts or the environment, and presents less of a threat to public health...
- High infection rate of Wolbachia endobacteria in the sand flea Tunga penetrans from BrazilJorg Heukelbach
Department of Community Health, School of Medicine, Federal University of Ceará State, Fortaleza, Brazil
Acta Trop 92:225-30. 2004..penetrans. Since Wolbachia were suggested as targets for intervention of insect pests and human filariasis, sand fleas were collected from infested humans, dogs and rats in a hyperendemic area in northeastern Brazil, and screened for ..
- Comparative in vivo adulticidal activity of a topical dinotefuran versus an imidacloprid-based formulation against cat fleas (Ctenocephalides felis) on catsMartin Murphy
Charles River Laboratories Preclinical Services Ireland, Carrentrila, Ballina, Co Mayo, Ireland
Vet Ther 10:9-16. 2009b>Fleas cause significant discomfort to pet cats and distress to their owners and are also vectors of disease severe infestations can cause anemia or flea allergy dermatitis and can lead to infections with Dipylidium caninum and Bartonella ..
- Fleas of elephant shrews (Mammalia, Macroscelididae) and a new host and locality record for Macroscelidopsylla albertyni De Meillon & Marcus, 1958 (Siphonaptera, Chimaeropsyllidae)J C Beaucournu
Universite de Rennes, Faculte de Medecine, Parasitologie et Zoologie appliquée, Rennes, France
Onderstepoort J Vet Res 70:251-3. 2003b>Fleas collected from the elephant shrews Elephantulus edwardii (A...
- Efficacy of a combination of a fipronil-(S)-methoprene spot-on formulation and a deltamethrin-impregnated collar in controlling fleas and sandflies on dogsM Franc
Ecole Nationale Veterinaire de Toulouse, Toulouse, France
Vet Ther 10:71-7. 2009..collar and a fipronil-(S)-methoprene spot-on formulation, in combination to protect dogs against sandflies and fleas when they live in or travel to leishmaniasis-enzootic areas. Interactions, tolerance, and efficacy were evaluated...
- Efficacy of the compound preparation imidacloprid 10%/permethrin 50% spot-on against ticks (I. ricinus, R. sanguineus) and fleas (Ct. felis) on dogsC Epe
Institute of Parasitology, Hannover School of Veterinary Medicine, Bunteweg 17, D 30559 Hannover, Germany
Parasitol Res 90:S122-4. 2003
- Evaluation of topical application of 10% imidacloprid-1% moxidectin to prevent Bartonella henselae transmission from cat fleasChristina A Bradbury
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
J Am Vet Med Assoc 236:869-73. 2010..To determine whether monthly topical administration of a combination of 10% imidacloprid and 1% moxidectin would lessen flea (Ctenocephalides felis) transmission of Bartonella henselae among cats...
- Editorial: Cutaneous larva migrans and tungiasis: the challenge to control zoonotic ectoparasitoses associated with povertyJorg Heukelbach
Trop Med Int Health 7:907-10. 2002
- Field trial of the efficacy of a combination of imidacloprid and permethrin against Tunga penetrans (sand flea, jigger flea) in dogs in BrazilS Klimpel
Institute of Zoomorphology, Cell Biology and Parasitology, Heinrich Heine University, Dusseldorf, Germany
Parasitol Res 97:S113-9. 2005..Since the dogs distribute the flea eggs throughout the village, leading to a high incidence of tungiasis in humans, treatment of dogs probably also decreases the number of cases of tungiasis in the latter...
- The patterns of tungiasis in Araruama township, state of Rio de Janeiro, BrazilRaimundo Wilson de Carvalho
Laboratório de Ixodides, Departamento de Entomologia, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, RJ, 21045 900, Brasil
Mem Inst Oswaldo Cruz 98:31-6. 2003....
- Infestation of Wistar rats with Tunga penetrans in different microenvironmentsLars Witt
Institute of Microbiology and Hygiene, and Institute of Tropical Medicine, Charite University Medicine, Berlin, Germany
Am J Trop Med Hyg 76:666-8. 2007..During a period of two weeks, the animals were monitored and the number of embedded fleas was documented...
- Detection and identification of Bartonella sp. in fleas from carnivorous mammals in Andalusia, SpainF J Marquez
Departamento Biologia Animal, Biología Vegetal y Ecología, Universidad de Jaen, 23071 Jaen, Spain
Med Vet Entomol 23:393-8. 2009A total of 559 fleas representing four species (Pulex irritans, Ctenocephalides felis, Ctenocephalides canis and Spilopsyllus cuniculi) collected on carnivores (five Iberian lynx Lynx pardinus, six European wildcat Felis silvestris, 10 ..
- New methods and strategies for monitoring susceptibility of fleas to current flea control productsByron L Blagburn
Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA
Vet Ther 7:86-98. 2006A flea larval bioassay was developed by an international team of scientists to monitor the susceptibility of fleas (Ctenocephalides felis) to imidacloprid (Advantage, Bayer HealthCare)...
- Morbidity assessment in sand flea disease (tungiasis)Judith Dorothea Kehr
Institute of Microbiology and Hygiene, Charite University Medicine, Campus Benjamin Franklin, Hindenburgdamm 27, 12203, Berlin, Germany
Parasitol Res 100:413-21. 2007..score for acute disease symptoms significantly correlated with the infestation rate and the number of embedded fleas. It turned zero when reinfestation was prevented...
- Pigs are the most important animal reservoir for Tunga penetrans (jigger flea) in rural NigeriaUade S Ugbomoiko
Department of Zoology, University of Ilorin, Ilorin, Nigeria
Trop Doct 38:226-7. 2008..4%; median = 1.5). Of all the tungiasis lesions identified 83% were found in pigs. Our data confirm that tungiasis is a zoonotic disease, and that pigs are its most important animal reservoir in this endemic community...
- Acute oral toxicity of Yersinia pseudotuberculosis to fleas: implications for the evolution of vector-borne transmission of plagueDavid L Erickson
Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, NIH, NIAID, Hamilton, MT 59840, USA
Cell Microbiol 9:2658-66. 2007..from Yersinia pseudotuberculosis</= 20 000 years ago, during which time it evolved to be transmitted by fleas. In comparing the ability of these closely related species to infect the rat flea Xenopsylla cheopis, we found ..
- Bacterial communities of Bartonella-positive fleas: diversity and community assembly patternsRyan T Jones
Department of Ecology and Evolutionary Biology, CB334, University of Colorado Boulder, Boulder, Colorado 80309, USA
Appl Environ Microbiol 74:1667-70. 2008We investigated the bacterial communities of nine Bartonella-positive fleas (n = 6 Oropsylla hirsuta fleas and n = 3 Oropsylla montana fleas), using universal primers, clone libraries, and DNA sequencing...
- Detection of Rickettsia typhi and seasonal prevalence of fleas collected from small mammals in the Republic of KoreaHeung Chul Kim
5th Medical Detachment, 168 Multifunctional Medical Battalion, US Army MEDDAC Korea, Unit 15247, APO AP 96205 5247
J Wildl Dis 46:165-72. 2010b>Fleas were collected from live-captured small mammals to identify potential flea-borne pathogens, seasonal prevalence of flea species, and host preference as part of the US military rodent-borne diseases surveillance program conducted at ..
- Early-phase transmission of Yersinia pestis by unblocked Xenopsylla cheopis (Siphonaptera: Pulicidae) is as efficient as transmission by blocked fleasRebecca J Eisen
Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Zoonotic, Enteric and Vector Borne Diseases, Centers for Disease Control and Prevention, PO Box 2087, Fort Collins, CO 80522, USA
J Med Entomol 44:678-82. 2007..However, if fleas remain blocked and continue to feed, they usually die within 5 d of blocking, resulting in a short infectious ..
- Potential role for dog fleas in the cycle of Leishmania sppMarilia Gabriele Prado Albuquerque Ferreira
Departamento de Clinica, Cirurgia e Reproducao Animal, Faculdade de Odontologia, Curso de Medicina Veterinaria, Universidade Estadual Paulista, Aracatuba, Sao Paulo, Brazil
Vet Parasitol 165:150-4. 2009..may also be transmitted by arthropods such as ticks and fleas. To investigate the possible role of dog fleas in the transmission of Leishmania spp...
- Development of quantitative real-time PCR assays to detect Rickettsia typhi and Rickettsia felis, the causative agents of murine typhus and flea-borne spotted feverKatherine M Henry
Rickettsial Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910 7500, USA
Mol Cell Probes 21:17-23. 2007..typhi and R. felis nucleic acid in the cat flea, Ctenocephalides felis. These results demonstrate that two sensitive and specific qPCR assays have been successfully developed to detect and enumerate R. typhi and R. felis...
- Systemic efficacy of nodulisporamides against fleas on dogsW L Shoop
Merck Research Laboratories, Merck and Co, Inc, Rahway, New Jersey 07065, USA
J Parasitol 87:1150-4. 2001..Parasite challenges were made by placing 100 live Ctenocephalides felis fleas onto the dorsum of dogs every 48 hr and examining efficacy at each of those intervals over a 22-day period...
- Preliminary studies on the effectiveness of the novel pulicide, spinosad, for the treatment and control of fleas on dogsDaniel E Snyder
Elanco Animal Health Research and Development, A Division of Eli Lilly and Company, Greenfield, IN 46140, USA
Vet Parasitol 150:345-51. 2007....
- Discovery of the development candidate N-tert-butyl nodulisporamide: a safe and efficacious once monthly oral agent for the control of fleas and ticks on companion animalsPeter T Meinke
Merck Research Laboratories, Rahway, NJ 07065 0900, USA
J Med Chem 52:3505-15. 2009Nodulisporic acid A (1) is a structurally complex fungal metabolite that exhibits systemic efficacy against fleas via modulation of an invertebrate specific glutamate-gated ion channel...
- The prevalence of Bartonella, hemoplasma, and Rickettsia felis infections in domestic cats and in cat fleas in OntarioAli Kamrani
Department of Pathobiology, Centre for Public Health and Zoonoses, University of Guelph, Ontario
Can J Vet Res 72:411-9. 2008..The prevalence of Rickettsia felis in cat fleas was also assessed. A pool of fleas from each of 50 flea-infested cats was analyzed for the presence of R...
- New Wolbachia endosymbionts from Nearctic and Neotropical fleas (Siphonaptera)Katharina Dittmar
Department of Integrative Biology, Brigham Young University, Provo, Utah 84606, USA
J Parasitol 90:953-7. 2004Several species of fleas (Siphonaptera), ectoparasites of mammals and birds, have recently been shown to harbor species of Wolbachia...
- Feline Advantage Heart (imidacloprid and moxidectin) topical solution as monthly treatment for prevention of heartworm infection (Dirofilaria immitis) and control of fleas (Ctenocephalides felis) on catsR G Arther
Bayer HealthCare LLC, Animal Health Division, Shawnee Mission, Kansas, USA
Parasitol Res 90:S137-9. 2003
- Molecular identification of Rickettsia felis in ticks and fleas from an endemic area for Brazilian Spotted FeverK A Oliveira
Laboratório de Bioquímica e Biologia Molecular de Agentes Infecciosos e Parasitários, Depatamento de Bioquímica e Biologia Molecular, Universidade Federal de Vicosa, Vicosa, MG, 36570 000, Brasil
Mem Inst Oswaldo Cruz 103:191-4. 2008..Moreover, they show the needing of further studies for deeper knowledge of R. felis-spotted fever epidemiology and differentiation of these diseases in Brazil...
- A longitudinal study of Bartonella infection in populations of woodrats and their fleasChristina Morway
Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
J Vector Ecol 33:353-64. 2008..Little is known about Bartonella infections in woodrat hosts and their fleas and how woodrat-flea associations may affect the dynamics of Bartonella infections...
- Field trial of systemically delivered arthropod development-inhibitor (fluazuron) used to control woodrat fleas (Siphonaptera: Ceratophyllidae) and ticks (Acari: Ixodidae)T J Slowik
Division of Insect Biology, Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720-3112, USA
J Med Entomol 38:75-84. 2001..When compared with control woodrats, the numbers of fleas [primarily Orchopeas sexdentatus (Baker)] on treated woodrats were significantly reduced 3-4 mo after initial ..
- European multicenter field trial on the efficacy and safety of a topical formulation of imidacloprid and permethrin (Advantix) in dogs naturally infested with ticks and/or fleasK Hellmann
Klifovet AG Munich, D 80689 Munich, Germany
Parasitol Res 90:S125-6. 2003
- Tick- and flea-borne rickettsial emerging zoonosesPhilippe Parola
Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, 13385 Marseille Cedex 5, France
Vet Res 36:469-92. 2005..A new spotted fever rickettsia, R. felis was also found to be associated with fleas and to be a human pathogen...
- Use of a chitin synthesis inhibitor to control fleas on wild rodents important in the maintenance of plague, Yersinia pestis, in CaliforniaRichard M Davis
Vector Borne Disease Section, California Department of Public Health, 342 Tyrus Court, Nipomo, CA 93444, USA
J Vector Ecol 33:278-84. 2008A study was designed to test the insect development inhibitors fluazuron and lufenuron for the control of fleas on sylvatic rodents as an adjunct to the control of plague...
- Sampling fleas: the reliability of host infestation dataB R Krasnov
Ramon Science Center, Jacob Blaustein Institute for Desert Research, Ben Gurion University of the Negev, Israel
Med Vet Entomol 18:232-40. 2004..The abundance of fleas collected from host bodies and collected from host burrows was compared among 55 flea species, controlling for the ..
- Zoonotic Bartonella species in fleas collected on gray foxes (Urocyon cinereoargenteus)Mourad W Gabriel
Department of Wildlife, Humboldt State University, Arcata, California, USA
Vector Borne Zoonotic Dis 9:597-602. 2009..rochalimae and B. vinsonii subsp. berkhoffii. Fleas (range 1-8 fleas per fox) were collected from 22 (41...
- Fleas (siphonaptera) collected from small mammals in Southern Viet Nam in 1997-1998G H Adler
Department of Biology and Microbiology, University of Wisconsin, Oshkosh, 54901, USA
J Med Entomol 38:210-3. 2001We report on fleas collected from small mammals in two forests, a lowland semideciduous dipterocarp forest and a highland evergreen forest, in southern Viet Nam...
- Small rodents fleas from the bubonic plague focus located in the Serra dos Orgãos Mountain Range, State of Rio de Janeiro, BrazilR W de Carvalho
Laboratório de Ixodides, Departamento de Entomologia, Instituto Oswaldo Cruz, Fundação do Instituto Oswaldo Cruz, 21045 900 Rio de Janeiro, RJ, Brasil
Mem Inst Oswaldo Cruz 96:603-9. 2001Eleven species of fleas were collected from 601 small rodents, from November 1995 to October 1997, in areas of natural focus of bubonic plague, including the municipalities of Nova Friburgo, Sumidouro and Teresópolis, State of Rio de ..
- Quantitative competitive PCR as a technique for exploring flea-Yersina pestis dynamicsD M Engelthaler
Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA
Am J Trop Med Hyg 62:552-60. 2000We used a quantitative competitive polymerase chain reaction assay to quantify Yersinia pestis loads in fleas and bacteremia levels in mice that were used as sources of infectious blood meals for feeding the fleas...
- A survey of bacterial diversity in ticks, lice and fleas from AustraliaAnna Murrell
Department of Microbiology and Parasitology and Institute for Molecular Bioscience, ARC Special Research Centre for Functional and Applied Genomics, University of Queensland, Brisbane, 4072 QLD, Australia
Parasitol Res 89:326-34. 2003We isolated bacteria from ticks, lice and fleas. Partial small subunit rRNA sequences were obtained for each isolate and the closest matches in the FastA database were determined...
- Abiotic factors influencing the ecology of wild rabbit fleas in north-eastern SpainJ J Osacar-Jimenez
, Facultad de Veterinaria, Zaragoza, Spain
Med Vet Entomol 15:157-66. 2001During 1992, the population dynamics of rabbit fleas were compared at two sites in north-eastern Spain. The sites differed mainly in terms of annual rainfall and soil type...
- The effect of behavioural interactions on the transfer of fleas (Siphonaptera) between two rodent speciesB R Krasnov
Ramon Science Center, Jacob Blaustein Institute for Desert Research, Ben-Gurion University of the Negev, P.O. Box 194, Mizpe Ramon 80600, Israel
J Vector Ecol 26:181-90. 2001The transfer of fleas between the house mouse, Mus musculus, and the midday jird, Meriones meridianus, through social contacts was studied by performing interspecific dyadic encounters on a neutral arena. M. meridianus and M...
- Density-dependent host selection in ectoparasites: an application of isodar theory to fleas parasitizing rodentsBoris R Krasnov
Ramon Science Centre and Mitrani Department of Desert Ecology, Jacob Blaustein Institute for Desert Research, Ben Gurion University of the Negev, P O Box 194, 80600 Mizpe Ramon, Israel
Oecologia 134:365-72. 2003..We applied this approach to study host selection of five fleas, each infesting two desert rodents...
- Role of the Yersinia pestis plasminogen activator in the incidence of distinct septicemic and bubonic forms of flea-borne plagueFlorent Sebbane
Laboratory of Zoonotic Pathogens and Veterinary Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
Proc Natl Acad Sci U S A 103:5526-30. 2006Yersinia pestis is transmitted by fleas and causes bubonic plague, characterized by severe local lymphadenitis that progresses rapidly to systemic infection and life-threatening septicemia...
- Natural history of plague: perspectives from more than a century of researchKenneth L Gage
Bacterial Zoonoses Branch, Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80523, USA
Annu Rev Entomol 50:505-28. 2005..variation among plague strains; the dynamics and maintenance of transmission cycles; mechanisms by which fleas transmit Y...
- Metapopulation dynamics of bubonic plagueM J Keeling
Department of Zoology, University of Cambridge, UK
Nature 407:903-6. 2000..The existence of plague reservoirs in wild rodent populations has important public-health implications for the transmission to urban rats and the subsequent risk of human outbreaks...
- Prevalence and infection load dynamics of Rickettsia felis in actively feeding cat fleasKathryn E Reif
Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana, United States of America
PLoS ONE 3:e2805. 2008..felis is a flea-associated rickettsial pathogen recurrently identified in both colonized and wild-caught cat fleas, Ctenocephalides felis. We hypothesized that within colonized fleas, the intimate relationship between R...
- Early-phase transmission of Yersinia pestis by cat fleas (Ctenocephalides felis) and their potential role as vectors in a plague-endemic region of UgandaRebecca J Eisen
Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Zoonotic, Enteric and Vector Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA
Am J Trop Med Hyg 78:949-56. 2008..In northwest Uganda, which has had recent plague outbreaks, cat fleas (Ctenocephalides felis) have been reported as the most common fleas in the home environment, which is suspected to ..
- Progress and opportunities in the development of vaccines against mites, fleas and myiasis-causing flies of veterinary importanceA J Nisbet
Moredun Research Institute, Edinburgh, UK
Parasite Immunol 28:165-72. 2006....
- Vertical transmission of Rickettsia felis in the cat flea (Ctenocephalides felis Bouché)Jimmy Wedincamp
Department of Entomology, Louisiana State University AgCenter, Baton Rouge 70803 0001, USA
J Vector Ecol 27:96-101. 2002Rickettsia felis can be maintained in cat fleas by vertical transmission for up to 12 generations without the benefit of an infected host. Horizontal transmission or the acquisition of R...
- Analysis of Genetic Algorithm for Rule-Set Production (GARP) modeling approach for predicting distributions of fleas implicated as vectors of plague, Yersinia pestis, in CaliforniaJennifer C Z Adjemian
Center for Vectorborne Diseases, School of Veterinary Medicine, University of University of California, Davis, CA 95616, USA
J Med Entomol 43:93-103. 2006More than 20 species of fleas in California are implicated as potential vectors of Yersinia pestis...
- Early-phase transmission of Yersinia pestis by unblocked fleas as a mechanism explaining rapidly spreading plague epizooticsRebecca J Eisen
Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, PO Box 2087, Fort Collins, CO 80522, USA
Proc Natl Acad Sci U S A 103:15380-5. 2006..Dissemination of Yersinia pestis, the etiological agent of plague, by blocked fleas has been the accepted paradigm for flea-borne transmission...
- The effect of substrate on survival and development of two species of desert fleas (Siphonaptera: Pulicidae)B R Krasnov
Ramon Science Center, Jacob Blaustein Institute for Desert Research, Ben Gurion University of the Negev, P O Box 194, Mizpe Ramon 80600, Israel
Parasite 9:135-42. 2002b>Fleas Xenopsylla conformis mycerini and Xenopsylla ramesis replace each other on the same rodent host (Meriones crassus) in two habitats that differ in substrate texture (sand and loess-like sediments, respectively)...
- Optimized Growth Media to Detect Intracellular Bacteria Implicated in Chronic DisPATRICIA MASCARELLI; Fiscal Year: 2011..As Bartonella spp. are transmitted by a large number of arthropod vectors, including fleas, lice, sand flies, ticks, biting flies and potentially others, determining the appropriate bacteria to screen for ..
- Plague biofilm formation--regulation and functionROBERT DONALD PERRY; Fiscal Year: 2013..In nature, the bacterium cycles between mammals (mainly rodents) and fleas. The interaction of plague with fleas is facilitated by the formation of a biofilm...
- MURINE TYPHUS: VECTOR BIOLOGY AND TRANSMISSIONAbdu F Azad; Fiscal Year: 2013..typhi target, colonize and survive within the epithelial cells in fleas and endothelial cells in the mammalian host...
- The Role of Plasmids in Rickettsia BiologyULRIKE GERTRUD MUNDERLOH; Fiscal Year: 2013..Many Rickettsia species are associated with blood-feeding arthropods (ticks, lice, fleas and mites) that serve as vectors for their transmission to vertebrate hosts...
- Role of fleas in transmission of rickettsiae: ecology of flea-borne spotted feverKEVIN MACALUSO; Fiscal Year: 2009..Since first being described in colonized cat fleas, R. felis has also emerged as a human pathogen...
- Arthropod host-dependent influence on rickettsial pathogenicityKevin R Macaluso; Fiscal Year: 2013..Our long-term goal is to elucidate the molecular mechanisms that are critical to rickettsial transmission by fleas in order to better understand the epidemiology of flea-borne rickettsial diseases and identify points of ..
- MOLECULAR MECHANISMS OF YERSINIA PESTIS PERSISTENCE IN THE FLEA VECTORViveka Vadyvaloo; Fiscal Year: 2013..is a flea-borne zoonotic disease characterized by sylvatic cycles in wild rodent populations and their associated fleas. These sylvatic cycles are composed of an epizootic phase, which increases the risk of transmission and human ..
- Rickettsial Immunity During Tick TransmissionJOAO PEDRA; Fiscal Year: 2013..phagocytophilum. The outcome of this proposal is significantly wide in scope. Ticks, mosquitoes, biting flies, fleas and blood feeding bugs have evolved salivary proteins to modulate host defense...
- Yersinia pestis biofilm regulationCreg Darby; Fiscal Year: 2010Bubonic plague, one of the most virulent of bacterial infections, is spread by the bites of fleas persistently colonized by Yersinia pestis...
- Rapid Detection and Identification of Zoonotic PathogensJohn Dunn; Fiscal Year: 2007..were the main catalysts that promoted epidemics of these ancient afflictions, which are normally transmitted by fleas, lice and ticks...
- A STRATEGY FOR SPREADING GENES IN CHAGAS DISEASE VECTORSRavi Durvasula; Fiscal Year: 2004..cruzi (ants, crickets, fleas and cockroaches) but-may be exposed to CRUZIGARD will be determined...
- The Psa fimbriae of Yersinia pestis, an adhesin with protective immunogenic propeDieter M Schifferli; Fiscal Year: 2010..pestis is best known as the causative agent of bubonic plague, a disease transmitted by the bite of infected fleas. However, if inhaled, this pathogen also produces a severe primary pneumonia known as pneumonic plague, which is ..
- HOST-REGULATED DEVELOPMENT IN ARTHROPOD VECTORSDov Borovsky; Fiscal Year: 1993..Such diverse arthropods as mosquitoes and ticks, tsetse flies and bugs, sandflies and fleas and vectors of plant as well as animal infections have been the subjects of these studies...
- INTERACTION OF TSETSE--ITS SYMBIONTS AND TRYPANOSOMESSerap Aksoy; Fiscal Year: 2001..The basic knowledge obtained will strengthen our understanding of tsetse biology and will also provide information relevant to other important disease vectors which harbor similar symbionts (e.g., ticks, fleas, reduviid bugs etc.).
- BIOLOGY AND IMMUNOLOGY OF MALARIA PARASITE LIVER-STAGESAbdu Azad; Fiscal Year: 2005..falciparum EE-stages. Finally, we will define the contribution of P. yoelii liver-stage gene products in protective immunity via DNA immunizations. ..
- Generation of Genetically Attenuated RickettsiaeAbdu Azad; Fiscal Year: 2009..The underlying hypothesis tested is whether recombinant strains with altered genes maintain their immunogenicity within mammals and provide cross protection to subsequent challenge with virulent strains. ..
- Murine Typhus: Vector Biology & TransmissionAbdu Azad; Fiscal Year: 2007..it can be a household infection because of its intimate association with[unreadable] commensal animals and their fleas. Existing knowledge does not adequately[unreadable] explain many important features and mechanisms which are ..
- DEVELOPMENTAL NEUROTOXICITY OF OP INSECTICIDESJanice Chambers; Fiscal Year: 2006..abstract_text> ..
- SYNTHESIS OF CHLOROPEPTINS, GP120 CD4 BINDING INHIBITORSAMOS SMITH; Fiscal Year: 2001..abstract_text> ..
- Molecular dynamics of rickettsial infection in ticksKEVIN MACALUSO; Fiscal Year: 2006..These studies will further our understanding of both tick physiology and rickettsial transmission. ..
- Proximal determinants of risk for tularemia outbreaksSam Telford; Fiscal Year: 2004..tularensis in the environment; and, ultimately, a better understanding of F. tularensis-host interactions. ..
- Metabolism and Age-Related Organophosphate ToxicityJanice Chambers; Fiscal Year: 2005..These results will indicate the contribution of detoxication to toxicity level, and will allow more accurate predictions of age-related differences in toxicity. ..
- Perpetuation of Francisella tularensisSam R Telford; Fiscal Year: 2010..Taken together, these observations will provide a basis for understanding how the agent of tularemia is perpetuated on Martha's Vineyard, and why pneumonic human disease is prevalent there. ..
- INVASION BIOLOGY OF AEDES ALBOPICTUSLEON LOUNIBOS; Fiscal Year: 2009..Blood meal identifications and sugar content of wild-caught specimens will determine vertebrate hosts and nectar feeding, and effects of blood and sugar on adult fitness will be evaluated experimentally. ..
- SYNTHESIS OF SPONGISTATIN ANTITUMOR AGENTSAMOS SMITH; Fiscal Year: 2007..abstract_text> ..
- Yersinia pestis biofilms on C. elegansCreg Darby; Fiscal Year: 2008..their growth, a physical effect similar to the feeding blockage that occurs in the digestive tracts of infected fleas. These observations suggest that Y. pestis blocks fleas with a biofilm...
- Molecular Epidemiology of Xenoestrogen ExposureSusan Teitelbaum; Fiscal Year: 2008..Furthermore, data analysis approaches applied in this research project will be applicable to a wide range of environmentally associated diseases. ..
- Comparative rickettsial protein profiles during tick infectionKEVIN MACALUSO; Fiscal Year: 2007..To better understand the mechanisms of rickettsial virulence, this project seeks to examine the interplay between spotted fever group Rickettsia and the vector tick. [unreadable] [unreadable] [unreadable]..
- Design and Synthesis of HIV-1 Protease InhibitorsAMOS SMITH; Fiscal Year: 2004....
- Tick Susceptibility and Response to RickettsiaeKEVIN MACALUSO; Fiscal Year: 2004..Together, these experiments will further our understanding of the tick-rickettsiae relationship. ..
- NMR systems : 2 Bruker Avance 500 ConsolesAMOS SMITH; Fiscal Year: 2006..The areas of public health research include, among others, cancer, infectious diseases, neurodegenerative diseases such as Alzheimer's disease, and heart and cardiovascular disease. [unreadable] [unreadable] [unreadable]..
- Pesticide Toxicity to the Nervous and Endocrine SystemsJanice Chambers; Fiscal Year: 2006....