culicidae

Summary

Summary: A family of the order DIPTERA that comprises the mosquitoes. The larval stages are aquatic, and the adults can be recognized by the characteristic wing venation, the scales along the wing veins, and the long proboscis. Many species are of particular medical importance.

Top Publications

  1. pmc West Nile fever--a reemerging mosquito-borne viral disease in Europe
    Z Hubalek
    Institute of Vertebrate Biology, Academy of Sciences, Brno, Czech Republic
    Emerg Infect Dis 5:643-50. 1999
  2. ncbi A global perspective on the epidemiology of West Nile virus
    Laura D Kramer
    The Arbovirus Laboratories, Wadsworth Center, New York State Department of Health, Slingerlands, NY 12159, USA
    Annu Rev Entomol 53:61-81. 2008
  3. ncbi Mosquito behavior and vector control
    Helen Pates
    London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom
    Annu Rev Entomol 50:53-70. 2005
  4. pmc VectorBase: a data resource for invertebrate vector genomics
    Daniel Lawson
    European Bioinformatics Institute EMBL EBI, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK
    Nucleic Acids Res 37:D583-7. 2009
  5. ncbi Invasions by insect vectors of human disease
    L Philip Lounibos
    Florida Medical Entomology Laboratory, University of Florida, Vero Beach, Florida 32962, USA
    Annu Rev Entomol 47:233-66. 2002
  6. pmc Phylogeny of the genus Flavivirus
    G Kuno
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522 2087, USA
    J Virol 72:73-83. 1998
  7. pmc Epidemiology and transmission dynamics of West Nile virus disease
    Edward B Hayes
    Centers for Disease Control and Prevention, Fort Collins, Colorado 80526, USA
    Emerg Infect Dis 11:1167-73. 2005
  8. pmc Understanding the link between malaria risk and climate
    Krijn P Paaijmans
    Center for Infectious Disease Dynamics, Department of Entomology, Chemical Ecology Laboratory, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 106:13844-9. 2009
  9. pmc Emergence of Usutu virus, an African mosquito-borne flavivirus of the Japanese encephalitis virus group, central Europe
    Herbert Weissenbock
    Institute of Pathology and Forensic Veterinary Medicine, Vienna, Austria
    Emerg Infect Dis 8:652-6. 2002
  10. pmc A malaria transmission-directed model of mosquito life cycle and ecology
    Philip A Eckhoff
    Intellectual Ventures Laboratory, 1600 132nd Ave NE, Bellevue, WA 98004, USA
    Malar J 10:303. 2011

Research Grants

Detail Information

Publications373 found, 100 shown here

  1. pmc West Nile fever--a reemerging mosquito-borne viral disease in Europe
    Z Hubalek
    Institute of Vertebrate Biology, Academy of Sciences, Brno, Czech Republic
    Emerg Infect Dis 5:643-50. 1999
    ....
  2. ncbi A global perspective on the epidemiology of West Nile virus
    Laura D Kramer
    The Arbovirus Laboratories, Wadsworth Center, New York State Department of Health, Slingerlands, NY 12159, USA
    Annu Rev Entomol 53:61-81. 2008
    ..Vector control strategies, vaccines, and antivirals, which now must be considered on a global scale, are also discussed...
  3. ncbi Mosquito behavior and vector control
    Helen Pates
    London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom
    Annu Rev Entomol 50:53-70. 2005
    ..Prospects for genetic control by sterile males or genes rendering mosquitoes harmless to humans will depend on competitive mating behavior. These methods are hampered by the immigration of monogamous, already-mated females...
  4. pmc VectorBase: a data resource for invertebrate vector genomics
    Daniel Lawson
    European Bioinformatics Institute EMBL EBI, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK
    Nucleic Acids Res 37:D583-7. 2009
    ..We have continued to develop both the software infrastructure and tools for interrogating the stored data...
  5. ncbi Invasions by insect vectors of human disease
    L Philip Lounibos
    Florida Medical Entomology Laboratory, University of Florida, Vero Beach, Florida 32962, USA
    Annu Rev Entomol 47:233-66. 2002
    ..Propagule pressure, previous success, and adaptations to human habits appear to favor successful invasions by vectors...
  6. pmc Phylogeny of the genus Flavivirus
    G Kuno
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522 2087, USA
    J Virol 72:73-83. 1998
    ..We also resolved many of the past taxonomic problems by establishing phylogenetic relationships of the antigenically unclassified viruses with the well-established viruses and by identifying synonymous viruses...
  7. pmc Epidemiology and transmission dynamics of West Nile virus disease
    Edward B Hayes
    Centers for Disease Control and Prevention, Fort Collins, Colorado 80526, USA
    Emerg Infect Dis 11:1167-73. 2005
    ..This review highlights new information regarding the epidemiology and dynamics of WNV transmission, providing a new platform for further research into preventing and controlling WNV disease...
  8. pmc Understanding the link between malaria risk and climate
    Krijn P Paaijmans
    Center for Infectious Disease Dynamics, Department of Entomology, Chemical Ecology Laboratory, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 106:13844-9. 2009
    ..Such effects of short-term temperature fluctuations have not previously been considered but are central to understanding current malaria transmission and the consequences of climate change...
  9. pmc Emergence of Usutu virus, an African mosquito-borne flavivirus of the Japanese encephalitis virus group, central Europe
    Herbert Weissenbock
    Institute of Pathology and Forensic Veterinary Medicine, Vienna, Austria
    Emerg Infect Dis 8:652-6. 2002
    ..If established in central Europe, this virus may have considerable effects on avian populations; whether USUV has the potential to cause severe human disease is unknown...
  10. pmc A malaria transmission-directed model of mosquito life cycle and ecology
    Philip A Eckhoff
    Intellectual Ventures Laboratory, 1600 132nd Ave NE, Bellevue, WA 98004, USA
    Malar J 10:303. 2011
    ..Mathematical models for planning malaria eradication benefit from detailed representations of local mosquito populations, their natural dynamics and their response to campaign pressures...
  11. ncbi Control of Japanese encephalitis--within our grasp?
    Tom Solomon
    United Kingdom Medical Research Council, United Kingdom
    N Engl J Med 355:869-71. 2006
  12. pmc Combining indoor residual spraying and insecticide-treated net interventions
    Immo Kleinschmidt
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Trop Med Hyg 81:519-24. 2009
    ..76-0.81) in Bioko and 0.34 (95% CI = 0.21-0.56) in Zambezia. Although the effects of confounding cannot be excluded, these results provide encouragement that the additional resources for combining IRS and LLIN are justified...
  13. ncbi Malaria early warnings based on seasonal climate forecasts from multi-model ensembles
    M C Thomson
    International Research Institute for Climate and Society IRI, The Earth Institute at Columbia University, New York, New York 10964 8000, USA
    Nature 439:576-9. 2006
    ..In years in which the forecast probability distribution is different from that of climatology, malaria decision-makers can use this information for improved resource allocation...
  14. ncbi The Innovative Vector Control Consortium: improved control of mosquito-borne diseases
    Janet Hemingway
    Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, UK, L3 5QA
    Trends Parasitol 22:308-12. 2006
    ....
  15. ncbi Impact of sustained use of insecticide-treated bednets on malaria vector species distribution and culicine mosquitoes
    K A Lindblade
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 4770 Buford Hwy MS F 22, Atlanta GA 30333, USA
    J Med Entomol 43:428-32. 2006
    ..Reductions in culicines by ITNs may have implications for community perceptions of ITN effectiveness and for control of other diseases such as lymphatic filariasis...
  16. ncbi Melanization immune responses in mosquito vectors
    Bruce M Christensen
    Department of Animal Health and Biomedical Sciences, 1656 Linden Drive, University of Wisconsin, Madison, WI 53706, USA
    Trends Parasitol 21:192-9. 2005
    ....
  17. pmc Host heterogeneity dominates West Nile virus transmission
    A Marm Kilpatrick
    Consortium for Conservation Medicine, New York, NY 10001, USA
    Proc Biol Sci 273:2327-33. 2006
    ....
  18. pmc Sampling outdoor, resting Anopheles gambiae and other mosquitoes (Diptera: Culicidae) in western Kenya with clay pots
    M Odiere
    Vector Biology and Control Research Centre, Kenya Medical Research Institute, Kisumu, Kenya
    J Med Entomol 44:14-22. 2007
    Clay pots were analyzed as devices for sampling the outdoor resting fraction of Anopheles gambiae Giles (Diptera: Culicidae) and other mosquito species in a rural, western Kenya...
  19. ncbi Advances in dissecting mosquito innate immune responses to arbovirus infection
    Rennos Fragkoudis
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Summerhall, Edinburgh EH9 1QH, Scotland, UK
    J Gen Virol 90:2061-72. 2009
    ..In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signalling pathways, and cell death/apoptosis...
  20. pmc Vector competence of selected North American Culex and Coquillettidia mosquitoes for West Nile virus
    M R Sardelis
    Division of Tropical Public Health, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    Emerg Infect Dis 7:1018-22. 2001
    ..nigripalpus from Florida were competent but only moderately efficient vectors. Coquillettidia perturbans was an inefficient laboratory vector. As WNV extends its range, exposure of additional mosquito species may alter its epidemiology...
  21. pmc Development and application of two multiplex real-time PCR assays for the detection of Mycobacterium ulcerans in clinical and environmental samples
    Janet A M Fyfe
    Victorian Infectious Diseases Reference Laboratory, North Melbourne, Victoria, Australia
    Appl Environ Microbiol 73:4733-40. 2007
    ..This suite of new methods is enabling rapid progress in the understanding of the ecology of this important human pathogen...
  22. pmc Mycobacterium ulcerans in mosquitoes captured during outbreak of Buruli ulcer, southeastern Australia
    Paul D R Johnson
    Infectious Disease Department, Austin Health, Melbourne, Victoria, Australia
    Emerg Infect Dis 13:1653-60. 2007
    ..Forty-eight pools (5 species) were positive for insertion sequence IS2404 (maximum likelihood estimate 4.3/1,000), and we confirmed the presence of M. ulcerans in a subset of pools by detection of 3 additional PCR targets...
  23. ncbi Towards a comprehensive simulation model of malaria epidemiology and control
    T Smith
    Swiss Tropical Institute, Socinstrasse 57, PO Box, CH 4002 Basel, Switzerland
    Parasitology 135:1507-16. 2008
    ..The project thus provides a general platform for comparing, fitting, and evaluating different model structures, and for quantitative prediction of effects of different interventions and integrated control programmes...
  24. pmc Ultra-prolonged activation of CO2-sensing neurons disorients mosquitoes
    Stephanie Lynn Turner
    Cellular, Molecular, and Developmental Biology Program, University of California, Riverside, California 92521, USA
    Nature 474:87-91. 2011
    ..The three classes of CO(2)-response-modifying odours offer powerful instruments for developing new generations of insect repellents and lures, which even in small quantities can interfere with the ability of mosquitoes to seek humans...
  25. pmc Native microbiota shape insect vector competence for human pathogens
    Chris M Cirimotich
    W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe Street, Baltimore, MD 21205 2179, USA
    Cell Host Microbe 10:307-10. 2011
    ..These microbes may prove effective agents for manipulating the vector competence of malaria and other important human pathogens...
  26. ncbi Ecological and evolutionary determinants of host species choice in mosquito vectors
    Issa N Lyimo
    Public Health Entomology Unit, Ifakara Health Institute, Off Mlabani Passage, PO Box 53, Ifakara, Tanzania
    Trends Parasitol 25:189-96. 2009
    ....
  27. pmc Potential benefits, limitations and target product-profiles of odor-baited mosquito traps for malaria control in Africa
    Fredros O Okumu
    Biomedical and Environmental Sciences Thematic group, Ifakara Health Institute, Ifakara, United Republic of Tanzania
    PLoS ONE 5:e11573. 2010
    ..We investigated the potential benefits of such traps for preventing malaria transmission in Africa and the essential characteristics that they should possess so as to be effective...
  28. ncbi Arboviral survey of mosquitoes in two northern Italian regions in 2007 and 2008
    Mattia Calzolari
    Istituto Zooprofilattico Sperimentale della Lombardia e dell Emilia Romagna B Ubertini, Brescia, Italy
    Vector Borne Zoonotic Dis 10:875-84. 2010
    ....
  29. ncbi Reducing malaria by mosquito-proofing houses
    Steve W Lindsay
    School of Biological and Biomedical Sciences, University of Durham, Science Laboratories, South Road, Durham, UK
    Trends Parasitol 18:510-4. 2002
    ..The literature reviewed here demonstrates the enormous potential of these methods to reduce malaria, in the hope that it will stimulate scientific debate and further research...
  30. pmc Rift Valley fever, Mayotte, 2007-2008
    Daouda Sissoko
    Cellule Interrégionale d Epidémiologie de la Réunion et Mayotte, La Reunion, France
    Emerg Infect Dis 15:568-70. 2009
    ..Ten recent human RVF cases were detected, which confirms the indigenous transmission of RFV virus in Mayotte...
  31. ncbi Does kdr genotype predict insecticide-resistance phenotype in mosquitoes?
    Martin J Donnelly
    Vector Group, Liverpool School of Tropical Medicine, Liverpool L35QA, UK
    Trends Parasitol 25:213-9. 2009
    ..However, we emphasize that kdr genotype might explain only a portion of heritable variation in resistance and that diagnostic assays to test the importance of other resistance mechanisms in field populations are required...
  32. ncbi Association between land cover and habitat productivity of malaria vectors in western Kenyan highlands
    Stephen Munga
    Kenya Medical Research Institute, Kisumu, Kenya
    Am J Trop Med Hyg 74:69-75. 2006
    ..gambiae larvae, and consequently increase the risks of malaria transmission to the human population...
  33. ncbi Molecular epidemiological analysis of Japanese encephalitis virus in China
    Huan Yu Wang
    State Key Laboratory for Infectious Disease Prevention and Control, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 100 YingXinJie, XuanWuQu, Beijing 100052, People s Republic of China
    J Gen Virol 88:885-94. 2007
    ..The results suggest that genotype 1 JEV was introduced to China around 1979 and that JEV strains belonging to genotypes 1 and 3 circulate in China...
  34. pmc A modified experimental hut design for studying responses of disease-transmitting mosquitoes to indoor interventions: the Ifakara experimental huts
    Fredros O Okumu
    Biomedical and Environmental Sciences Thematic group, Ifakara Health Institute, Ifakara, Republic of Tanzania
    PLoS ONE 7:e30967. 2012
    ....
  35. pmc Phylogenetic analysis and temporal diversification of mosquitoes (Diptera: Culicidae) based on nuclear genes and morphology
    Kyanne R Reidenbach
    Eck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA
    BMC Evol Biol 9:298. 2009
    ..The generic and suprageneric relationships within mosquitoes (Diptera: Culicidae) are poorly resolved, making these subjects difficult to address.
  36. pmc Weather-based prediction of Plasmodium falciparum malaria in epidemic-prone regions of Ethiopia I. Patterns of lagged weather effects reflect biological mechanisms
    Hailay D Teklehaimanot
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Malar J 3:41. 2004
    ..The impact of temperature on the duration of a mosquito's life cycle and the sporogonic phase of the parasite could explain the inconsistent findings...
  37. ncbi 2009 West Nile disease epidemic in Italy: first evidence of overwintering in Western Europe?
    F Monaco
    Istituto Zooprofilattico Sperimentale dell Abruzzo e Molise G Caporale, Via Campo Boario, 64100 Teramo, Italy
    Res Vet Sci 91:321-6. 2011
    ....
  38. pmc Mosquito, bird and human surveillance of West Nile and Usutu viruses in Emilia-Romagna Region (Italy) in 2010
    Mattia Calzolari
    Istituto Zooprofilattico Sperimentale della Lombardia e dell Emilia Romagna B Ubertini, Brescia, Italy
    PLoS ONE 7:e38058. 2012
    ..Surveillance was improved in following years by extending the monitoring to larger areas and increasing the numbers of mosquitoes and birds tested...
  39. pmc An affordable, quality-assured community-based system for high-resolution entomological surveillance of vector mosquitoes that reflects human malaria infection risk patterns
    Prosper P Chaki
    Ifakara Health Institute, Coordination Office, Kiko Avenue, Mikocheni, PO Box 78373, Dar es Salaam, United Republic of Tanzania
    Malar J 11:172. 2012
    ..A large-scale larviciding programme in urban Dar es Salaam, Tanzania is supported by a community-based (CB) system for trapping adult mosquito densities to monitor programme performance...
  40. ncbi Laboratory wash resistance of long-lasting insecticidal nets
    John E Gimnig
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Trop Med Int Health 10:1022-9. 2005
    ....
  41. ncbi Fine-scale genetic variation and evolution of West Nile Virus in a transmission "hot spot" in suburban Chicago, USA
    Luigi Bertolotti
    Universita degli Studi di Torino, Dipartimento di Produzioni Animali, Epidemiologia, Ecologia, Via Leonardo da Vinci, 44, 10095 Grugliasco TO, Italy
    Virology 374:381-9. 2008
    ..These results indicate that WNV transmission and evolutionary dynamics can vary seasonally and in response to fine-scale environmental conditions and landscape characteristics related to urbanization...
  42. pmc The entomological inoculation rate and Plasmodium falciparum infection in African children
    D L Smith
    Fogarty International Center, National Institutes of Health, Building 16, 16 Center Drive, Bethesda, Maryland 20892, USA
    Nature 438:492-5. 2005
    ..The results have important implications for public health interventions: the success of malaria control will depend heavily on whether efforts are targeted at those who are most at risk of infection...
  43. ncbi Mosquito/microbiota interactions: from complex relationships to biotechnological perspectives
    Irene Ricci
    Scuola di Bioscienze e Biotecnologie, Universita degli Studi di Camerino, 62032 Camerino, Italy
    Curr Opin Microbiol 15:278-84. 2012
    ....
  44. pmc Barrier screens: a method to sample blood-fed and host-seeking exophilic mosquitoes
    Thomas R Burkot
    James Cook University, Queensland Tropical Health Alliance, Cairns, QLD 4870, Australia
    Malar J 12:49. 2013
    ....
  45. ncbi Vector competence of selected African mosquito (Diptera: Culicidae) species for Rift Valley fever virus
    Michael J Turell
    Virology Division, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702 5011, USA
    J Med Entomol 45:102-8. 2008
    ..The recent introduction and spread of West Nile virus into the Americas and the spread of RVFV to the Arabian Peninsula illustrates the potential for viruses, once enzootic in Africa, to spread to other parts of the world...
  46. pmc The risk of a mosquito-borne infection in a heterogeneous environment
    David L Smith
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA
    PLoS Biol 2:e368. 2004
    ..Finally, we show that estimates for the average risk of infection that are based on the average entomological inoculation rate are strongly biased in heterogeneous environments...
  47. pmc Filarial worms reduce Plasmodium infectivity in mosquitoes
    Matthew T Aliota
    Department of Pathobiological Sciences, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS Negl Trop Dis 5:e963. 2011
    ..Ar. subalbatus used in this study are natural vectors of P. gallinaceum and B. pahangi and they are naturally refractory to B. malayi (melanization-based refractoriness)...
  48. ncbi Molecular phylogeny and evolutionary relationships among mosquitoes (Diptera: Culicidae) from the northeastern United States based on small subunit ribosomal DNA (18S rDNA) sequences
    John J Shepard
    Department of Soil and Water, The Connecticut Agricultural Experiment Station, 123 Huntington Street, P O Box 1106, New Haven, CT 06504, USA
    J Med Entomol 43:443-54. 2006
    The phylogenetic relationships of Culicidae native to the northeastern United States were investigated by analyzing small subunit ribosomal DNA (18S rDNA) sequences obtained from 39 species representing nine genera...
  49. pmc A new classification system for the actions of IRS chemicals traditionally used for malaria control
    John P Grieco
    Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America
    PLoS ONE 2:e716. 2007
    ..The new classification scheme will characterize chemicals on the basis of spatial repellent, contact irritant and toxic actions...
  50. ncbi Alternative insecticides: an urgent need
    Morteza Zaim
    Strategy Development and Monitoring for Parasitic Diseases and Vector Control, Communicable Disease Control, Prevention and Eradication, World Health Organization, 1211 Geneva 27, Switzerland
    Trends Parasitol 18:161-3. 2002
    ..Mobilizing public resources and establishment of partnerships to support research and development of public health insecticides is crucial in the post-DDT and post-pyrethroid era...
  51. ncbi Mosquito transgenesis: what is the fitness cost?
    Mauro T Marrelli
    Johns Hopkins University, Bloomberg School of Public Health Department of Molecular Microbiology and Immunology and Malaria Research Institute, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Trends Parasitol 22:197-202. 2006
    ..Studies to assess fitness of transgenic mosquitoes in the field (as opposed to the laboratory) are still needed...
  52. ncbi Dynamics of flavivirus infection in mosquitoes
    Laura D Kramer
    Arbovirus Laboratories, Wadsworth Center, New York State Department of Health, Slingerlands, New York 12159, USA
    Adv Virus Res 60:187-232. 2003
  53. ncbi The ecology and epidemiology of Kunjin virus
    R A Hall
    Department of Microbiology and Parasitology, School of Molecular and Microbial Sciences, The University of Queensland, St Lucia, Queensland 4072, Australia
    Curr Top Microbiol Immunol 267:253-69. 2002
  54. pmc Evidence of simultaneous circulation of West Nile and Usutu viruses in mosquitoes sampled in Emilia-Romagna region (Italy) in 2009
    Mattia Calzolari
    Istituto Zooprofilattico Sperimentale della Lombardia e dell Emilia Romagna B Ubertini IZSLER, Brescia, Italy
    PLoS ONE 5:e14324. 2010
    ..An extensive entomological survey was performed in 2009 to establish the presence and distribution of mosquito arboviruses in this region, with particular reference to flaviviruses...
  55. ncbi Bacillus thuringiensis serovariety israelensis and Bacillus sphaericus for mosquito control
    Lawrence A Lacey
    Yakima Agricultural Research Laboratory, USDA ARS, 5230 Konnowac Pass Road, Wapato, WA 98951, USA
    J Am Mosq Control Assoc 23:133-63. 2007
    ..sphaericus can be ideal control agents in integrated programs especially where other biological control agents, environmental management, personal protection and the judicious use of insecticides are combined...
  56. pmc Revisiting the basic reproductive number for malaria and its implications for malaria control
    David L Smith
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Biol 5:e42. 2007
    ..Therefore, strategic planning for malaria control should consider R0, the spatial scale of transmission, human population density, and heterogeneous biting...
  57. ncbi The global spread of malaria in a future, warmer world
    D J Rogers
    Trypanosomiasis and Land Use in Africa Research Group, Oxford Tick Research Group, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Science 289:1763-6. 2000
    ..These results were applied to future climate scenarios to predict future distributions, which showed remarkably few changes, even under the most extreme scenarios...
  58. pmc Proteolytic activation of tick-borne encephalitis virus by furin
    K Stadler
    Institute of Virology, University of Vienna, Austria
    J Virol 71:8475-81. 1997
    ..In vivo, prM cleavage was blocked by a furin inhibitor, and infection of the furin-deficient cell line LoVo yielded only immature virions, suggesting that furin is essential for cleavage activation of flaviviruses...
  59. pmc Rift Valley fever virus epidemic in Kenya, 2006/2007: the entomologic investigations
    Rosemary Sang
    Arbovirology Hemorrhagic Fevers Laboratory, Centre for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya
    Am J Trop Med Hyg 83:28-37. 2010
    ....
  60. ncbi Isolation and full-length sequence analysis of Armigeres subalbatus totivirus, the first totivirus isolate from mosquitoes representing a proposed novel genus (Artivirus) of the family Totiviridae
    Yougang Zhai
    State Key Laboratory for Infectious Disease Prevention and Control, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100052, PR China
    J Gen Virol 91:2836-45. 2010
    ..AsTV was shown to grow in both mosquito and mammalian cells, suggesting that it is an arbovirus that can infect mammals...
  61. ncbi Manipulation of medically important insect vectors by their parasites
    Hilary Hurd
    Centre for Applied Entomology and Parasitology, School of Life Sciences, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom
    Annu Rev Entomol 48:141-61. 2003
    ..Examples are mainly drawn from malaria-infected mosquitoes, Leishmania-infected sandflies, and Trypanosoma-infected tsetse flies...
  62. ncbi Towards a fuller understanding of mosquito behaviour: use of electrocuting grids to compare the odour-orientated responses of Anopheles arabiensis and An. quadriannulatus in the field
    S J Torr
    Natural Resources Institute, University of Greenwich, Chatham, Kent, UK
    Med Vet Entomol 22:93-108. 2008
    ..of these odours, on the attraction, entry and landing responses of Anopheles arabiensis Giles (Diptera: Culicidae) and Anopheles quadriannulatus Theobald...
  63. ncbi Gene drive systems in mosquitoes: rules of the road
    Anthony A James
    Department of Microbiology, University of California, Irvine, CA 92697 3900, USA
    Trends Parasitol 21:64-7. 2005
    ....
  64. ncbi An outbreak of Japanese encephalitis in the Torres Strait, Australia, 1995
    J N Hanna
    Tropical Public Health Unit, Queensland Health, Cairns
    Med J Aust 165:256-60. 1996
    ..To determine the distribution of virus infection during an outbreak of Japanese encephalitis (JE) in the Torres Strait, and to describe the environmental factors facilitating the outbreak...
  65. pmc Source reduction of mosquito larval habitats has unexpected consequences on malaria transmission
    Weidong Gu
    Illinois Natural History Survey, Champaign, IL 61820, USA
    Proc Natl Acad Sci U S A 103:17560-3. 2006
    ..Our findings suggest that the prolonged duration of the gonotrophic cycle might be one of the important mechanisms underlying the effectiveness of environment-management interventions for malaria control...
  66. pmc The impact of repeated rounds of mass drug administration with diethylcarbamazine plus albendazole on bancroftian filariasis in Papua New Guinea
    Gary J Weil
    Washington University School of Medicine, St Louis, Missouri, USA
    PLoS Negl Trop Dis 2:e344. 2008
    ..This study employed various monitoring methods to assess the impact of repeated rounds of mass drug administration (MDA) on bancroftian filariasis in Papua New Guinea, which has the largest filariasis problem in the Pacific region...
  67. ncbi Isolation of West Nile virus from mosquitoes, crows, and a Cooper's hawk in Connecticut
    J F Anderson
    Department of Entomology, Department of Soil and Water, The Connecticut Agricultural Experiment Station, Post Office Box 1106, New Haven, CT 06504, USA
    Science 286:2331-3. 1999
    ..8 and 3.6 percent difference). If established in North America, WN virus will likely have severe effects on human health and on the health of populations of birds...
  68. pmc Mosquitoes smell and avoid the insect repellent DEET
    Zainulabeuddin Syed
    Honorary Maeda Duffey Laboratory, Department of Entomology, University of California Davis, 1 Shields Ave, Davis, CA 95616
    Proc Natl Acad Sci U S A 105:13598-603. 2008
    ..In a sugar-feeding assay, both female and male mosquitoes avoided DEET. In addition, mosquitoes responding only to physical stimuli avoided DEET...
  69. ncbi A real-time RT-PCR method for the universal detection and identification of flaviviruses
    G Moureau
    Unite des Virus Emergents, Faculte de Medecine, Marseille, France
    Vector Borne Zoonotic Dis 7:467-77. 2007
    ....
  70. ncbi Insecticide resistance in disease vectors of public health importance
    Ralf Nauen
    Bayer CropScience AG, Research, Biology Insecticides, Alfred Nobel Str 50, D 40789 Monheim, Germany
    Pest Manag Sci 63:628-33. 2007
    ..Moreover, the development of novel insecticide classes for control of adult mosquitoes and other vectors becomes increasingly important...
  71. pmc Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials
    Lucy C Okell
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Malar J 7:125. 2008
    ..The size of this effect is estimated in symptomatic P. falciparum infections...
  72. ncbi Quantitation of flaviviruses by fluorescent focus assay
    Anne F Payne
    The Arbovirus Laboratories, Wadsworth Center, New York State Department of Health, 5668 State Farm Rd, Slingerlands, NY 12159, USA
    J Virol Methods 134:183-9. 2006
    ..In addition, these viruses can be quantitated by FFA on a mosquito cell line (C6/36), which does not support plaque formation. The FFA for flaviviruses was validated for accuracy, precision, specificity, and robustness of the assay...
  73. ncbi Potential for North American mosquitoes (Diptera: Culicidae) to transmit rift valley fever virus
    Michael J Turell
    Department of Vector Assessment, Virology Division, United States Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, MD 21702, USA
    J Med Entomol 47:884-9. 2010
    ....
  74. pmc Exploring the contributions of bed nets, cattle, insecticides and excitorepellency to malaria control: a deterministic model of mosquito host-seeking behaviour and mortality
    Gerry F Killeen
    Ifakara Health Research and Development Centre, Box 53, Ifakara, Kilombero, Morogoro, United Republic of Tanzania
    Trans R Soc Trop Med Hyg 101:867-80. 2007
    ..As financial support, technology and distribution systems for insecticide-treated nets improve, massive reductions in malaria transmission could be realised...
  75. pmc The abundance and host-seeking behavior of culicine species (Diptera: Culicidae) and Anopheles sinensis in Yongcheng city, People's Republic of China
    Xiao Bo Liu
    State Key Laboratory for Infectious Disease Prevention and Control, China CDC Key Laboratory of Surveillance and Early Warning on Infectious Disease, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China
    Parasit Vectors 4:221. 2011
    ..sinensis in Yongcheng city, a representative region of P. vivax malaria. Specifically, we wished to determine the relative attractiveness of different animal baits versus human bait to culicine species and An. sinensis...
  76. pmc Urbanization, malaria transmission and disease burden in Africa
    Simon I Hay
    TALA Research Group in the Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Nat Rev Microbiol 3:81-90. 2005
    ..We find there were 1,068,505 malaria deaths in Africa in 2000 - a modest 6.7% reduction over previous iterations. The public-health implications of these findings and revised estimates are discussed...
  77. pmc Malaria transmission in Dakar: a two-year survey
    Frederic Pages
    Unité d entomologie médicale, Institut de Medecine Tropicale du Service de Sante des Armees, Marseille, France
    Malar J 7:178. 2008
    ..However; there was some evidence of local transmission based on reports of malaria among permanent residents. An entomological evaluation of malaria transmission was conducted from May 2005 to October 2006 in two areas of Dakar...
  78. ncbi Habitat-based larval interventions: a new perspective for malaria control
    Weidong Gu
    Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Am J Trop Med Hyg 78:2-6. 2008
    ....
  79. pmc Virus discovery by deep sequencing and assembly of virus-derived small silencing RNAs
    Qingfa Wu
    Department of Plant Pathology and Microbiology, Institute for Integrative Genome Biology, University of California, Riverside, CA 92521, USA
    Proc Natl Acad Sci U S A 107:1606-11. 2010
    ..We propose that invertebrate viruses discovered by this approach may include previously undescribed human and vertebrate viral pathogens that are transmitted by arthropod vectors...
  80. pmc Dengue viral infections
    G N Malavige
    Department of Clinical Immunology, A Floor, West Block, Queens Medical Centre, University Hospital, Nottingham NG7 2UH, UK
    Postgrad Med J 80:588-601. 2004
    ..This review outlines aspects of the epidemiology of dengue infections, the dengue virus and its mosquito vector, clinical features and pathogenesis of dengue infections, and the management and control of these infections...
  81. ncbi Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites
    Stephen L Hoffman
    Malaria Program, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20850, USA
    J Infect Dis 185:1155-64. 2002
    ....
  82. pmc Host feeding patterns of established and potential mosquito vectors of West Nile virus in the eastern United States
    Charles S Apperson
    Department of Entomology, North Carolina State University, Raleigh, North Carolina, USA
    Vector Borne Zoonotic Dis 4:71-82. 2004
    ..These findings suggest that vector species for West Nile virus may preferentially feed upon certain avian hosts...
  83. ncbi Identifying Canadian mosquito species through DNA barcodes
    A Cywinska
    Department of Biological Sciences, Brock University, St Catharines, Ontario, Canada
    Med Vet Entomol 20:413-24. 2006
    ..1 (CO1) region was used to provide the first CO1 barcodes for 37 species of Canadian mosquitoes (Diptera: Culicidae) from the provinces Ontario and New Brunswick...
  84. pmc Differential attraction of malaria mosquitoes to volatile blends produced by human skin bacteria
    Niels O Verhulst
    Laboratory of Entomology, Wageningen University and Research Centre, Wageningen, The Netherlands
    PLoS ONE 5:e15829. 2010
    ..This information will be used in the further development of a blend of semiochemicals for the manipulation of mosquito behaviour...
  85. ncbi Evaluation of four sampling techniques for surveillance of Culex quinquefasciatus (Diptera: Culicidae) and other mosquitoes in African rice agroecosystems
    Ephantus J Muturi
    Medical Entomology Laboratory, Centre for Ecological Entomology, Illinois Natural History Survey, 1816 Sooth Oak St, Champaign, IL 61820
    J Med Entomol 44:503-8. 2007
    ..traps and gravid traps against oviposition traps in outdoor collection of Culex quinquefasciatus Say (Diptera: Culicidae) and other mosquitoes...
  86. ncbi Evaluation of mosquitocidal activity of essential oil and sesquiterpenes from leaves of Chloroxylon swietenia DC
    S Ravi Kiran
    Department of Botany, Osmania University, Hyderabad, 500007, India
    Parasitol Res 101:413-8. 2007
    ..swietenia displayed remarkable mosquitocidal activity suggesting that the method could be extended for future field trials in various mosquito control programmes, and the results are compared with synthetic insecticides...
  87. ncbi Effect of food on immature development, consumption rate, and relative growth rate of Toxorhynchites splendens (Diptera: Culicidae), a predator of container breeding mosquitoes
    D Dominic Amalraj
    Vector Control Research Centre, Pondicherry, India
    Mem Inst Oswaldo Cruz 100:893-902. 2005
    ..This adaptive life characteristic strategy of this predator is useful for mass-rearing for large scale field release programmes in the control of container breeding mosquitoes is discussed...
  88. ncbi The genus and subgenus categories within Culicidae and placement of Ochlerotatus as a subgenus of Aedes
    Harry M Savage
    Centers for Disease Control and Prevention, PO Box 2087, Ft Collins, CO 80522, USA
    J Am Mosq Control Assoc 20:208-14. 2004
    Many species of Culicidae are of major medical, veterinary, and economic importance...
  89. ncbi Plasmodium differentiation in the mosquito
    R E Sinden
    Department of Biology, Imperial College of Science, Technology and Medicine, London, UK
    Parassitologia 41:139-48. 1999
    ..The potential exploitation of these interactions as possible mechanisms for intervention will be discussed...
  90. pmc Molecular xenomonitoring of Dirofilaria immitis and Dirofilaria repens in mosquitoes from north-eastern Italy by real-time PCR coupled with melting curve analysis
    Maria Stefania Latrofa
    Dipartimento di Sanità Pubblica e Zootecnia, Universita degli Studi di Bari, Strada Provinciale per Casamassima Km 3, 70010, Valenzano, Bari, Italy
    Parasit Vectors 5:76. 2012
    ..Our study aimed to evaluate the recently developed duplex real-time PCR for screening large number of culicids and to assess their positivity for D. immitis and D. repens in an area where both species are endemic...
  91. pmc North American West Nile virus genotype isolates demonstrate differential replicative capacities in response to temperature
    Christy C Andrade
    Center for Vector Borne Diseases and Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, CA, USA
    J Gen Virol 92:2523-33. 2011
    ..These data indicate that the NS1 and NS4A mutations identified in some WN02 isolates could reduce thermal stability and impede replication of virus at temperatures observed in febrile avian hosts...
  92. pmc Identification of the midgut microbiota of An. stephensi and An. maculipennis for their application as a paratransgenic tool against malaria
    Navid Dinparast Djadid
    Malaria and Vector Research Group, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
    PLoS ONE 6:e28484. 2011
    The midgut microbiota associated with Anopheles stephensi and Anopheles maculipennis (Diptera: Culicidae) was investigated for development of a paratransgenesis-based approach to control malaria transmission in Eastern Mediterranean ..
  93. ncbi Study on the protective efficacy of SA14-14-2 attenuated Japanese encephalitis against different JE virus isolates circulating in China
    Xinyu Liu
    Department of First Viral Vaccine, National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China
    Vaccine 29:2127-30. 2011
    ....
  94. pmc Comparison of the CDC Backpack aspirator and the Prokopack aspirator for sampling indoor- and outdoor-resting mosquitoes in southern Tanzania
    Marta F Maia
    Disease Control Department, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Parasit Vectors 4:124. 2011
    ..The following study evaluates the Prokopack aspirator compared to the CDC backpack aspirator when sampling resting mosquitoes in rural Tanzania...
  95. ncbi An update on mosquito cell expressed dengue virus receptor proteins
    Duncan R Smith
    Institute of Molecular Biosciences and Center for Emerging and Neglected Infectious Diseases, Mahidol University, Thailand
    Insect Mol Biol 21:1-7. 2012
    ..This short review aims to provide an update on our current understanding of the proteins expressed by mosquito cells that mediate DENV binding as a prerequisite to DENV entry and replication...
  96. ncbi The bacterium, Lysinibacillus sphaericus, as an insect pathogen
    Colin Berry
    Cardiff School of Biosciences, Cardiff University, Park Place, Cardiff CF10 3AT, UK
    J Invertebr Pathol 109:1-10. 2012
    ..Future studies of these could well lead to novel potent and environmentally compatible insecticidal products for controlling a range of insect pests and vectors of disease...
  97. pmc Distribution and phylogenetic comparisons of a novel mosquito flavivirus sequence present in Culex tarsalis Mosquitoes from western Canada with viruses isolated in California and Colorado
    Shaun Tyler
    National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
    Am J Trop Med Hyg 85:162-8. 2011
    ....
  98. ncbi Assessment of a novel real-time pan-flavivirus RT-polymerase chain reaction
    Nicholas Johnson
    Rabies and Wildlife Zoonoses Group, Veterinary Laboratories Agency, Addlestone, United Kingdom
    Vector Borne Zoonotic Dis 10:665-71. 2010
    ..The assay has been used to survey 160 bird samples and 1000 mosquito samples from the United Kingdom and found no evidence for WNV...
  99. ncbi Deep sequencing reveals extensive variation in the gut microbiota of wild mosquitoes from Kenya
    J Osei-Poku
    Department of Genetics, University of Cambridge, Cambridge, UK
    Mol Ecol 21:5138-50. 2012
    ..This may be an important factor in causing differences in disease transmission rates within mosquito populations...
  100. ncbi A duplex real-time polymerase chain reaction assay for the detection of and differentiation between Dirofilaria immitis and Dirofilaria repens in dogs and mosquitoes
    Maria Stefania Latrofa
    Dipartimento di Sanità Pubblica e Zootecnia, Universita degli Studi di Bari, Strada Provinciale per Casamassima Km 3, 70010 Valenzano Bari, Italy
    Vet Parasitol 185:181-5. 2012
    ..5 pg/μl and 3 × 10(-1)pg/μl for D. immitis and D. repens, respectively). This assay is proposed as a tool for the epidemiological surveillance of the two most important Dirofilaria species in areas where they are endemic and sympatric...
  101. pmc Development of multiplex real-time reverse transcriptase PCR assays for detecting eight medically important flaviviruses in mosquitoes
    Day Yu Chao
    Arboviral Diseases Branch, Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80521, USA
    J Clin Microbiol 45:584-9. 2007
    ....

Research Grants67

  1. Cellular Immune Response of Mosquitoes to Pathogens
    JULIAN HILLYER; Fiscal Year: 2003
    ..In understanding the immune response mounted by different insect species and strains toward pathogens, it may be possible to manipulate existing vectors to make the parasite/vector biologic interplay incompatible. ..
  2. MOLECULAR GENETICS OF OLFACTION IN ANOPHELINE MOSQUITOES
    LAURENCE ZWIEBEL; Fiscal Year: 2004
    ..olfaction plays a major role in host seeking and selection behavior of blood-feeding female mosquitoes (Diptera: Culicidae) and as such, constitutes a critical component of the mosquito's ability to transmit diseases such as malaria ..
  3. ARBOVIRUS PERSISTENCE IN SEASONAL WETLANDS
    William Reisen; Fiscal Year: 2002
    ..Virus ecology at wetlands in the Coachella Valley of southeastern California with consistent enzootic activity will be compared with wetlands in the southern San Joaquin Valley where virus activity currently is intermittent. ..
  4. HOST COMPETENCE FACTORS AFFECT ARBOVIRUS TRANSMISSION
    William Reisen; Fiscal Year: 2003
    ..Studies will assess how alternating sequential infections between vertebrate and vector species that are part of the natural transmission cycle may alter virus genetics and fitness. ..
  5. Nutritional and endocrine control of mosquito egg development.
    Aparna Telang; Fiscal Year: 2008
    ..Identification and characterization of these genes should expand our understanding of hematophagy and pathogen transmission in mosquito vectors. [unreadable] [unreadable] [unreadable] [unreadable]..
  6. Genotypic and Phenotypic Analysis of West Nile virus, Yucatan Peninsula of Mexico
    Bradley Blitvich; Fiscal Year: 2008
    ..This information will help determine why there has not been an epidemic of WNV in the YP, and will identify risk factors associated with WNV disease. [unreadable] [unreadable] [unreadable]..
  7. Mosquito-malaria interactions in the hemocoel
    JULIAN HILLYER; Fiscal Year: 2007
    ..Understanding the mechanisms used by parasites to complete their life cycle inside the vector, and the mechanisms used by the vector to kill parasites, may lead to novel transmission control strategies. [unreadable] [unreadable]..
  8. Population dynamics of sporogony in Thailand
    JEFFERSON VAUGHAN; Fiscal Year: 2003
    ....
  9. Microfilarial enhancement of Dengue transmission
    JEFFERSON VAUGHAN; Fiscal Year: 2002
    ....
  10. Malaria sporozoite gene exprssion in the mosquito
    Brenda Beerntsen; Fiscal Year: 2003
    ..Ultimately, this valuable information may be exploited to provide new additions to the arsenal of weapons available to control or eradicate malaria. ..
  11. FACTORS AFFECTING GROWTH OF BRUGIA MALAVI IN SCID MICE
    THIRUCHANDURAI RAJAN; Fiscal Year: 2005
    ....
  12. Brugia Infections in Mice: Role of Eosinophils
    THIRUCHANDURAI RAJAN; Fiscal Year: 2005
    ..We believe that the studies proposed herein will help us understand the mechanisms by which mammalian hosts combat infectious agents that are far larger than their own effector cells. ..
  13. CHITIN BIOSYNTHESIS AND THE MOSQUITO PERITROPHIC MATRIX
    Bruce Christensen; Fiscal Year: 2007
    ....
  14. ECOLOGY AND GENETICS OF VENEZUELAN EQUINE ENCEPHALITIS
    Scott Weaver; Fiscal Year: 2005
    ..This information will be invaluable in targeting prevention and control resources, especially for obtaining maximum benefit in developing countries with limited resources. ..
  15. FACTORS AFFECTING GROWTH OF BRUGIA MALAYI IN SCID MICE
    THIRUCHANDURAI RAJAN; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  16. Plasmodium sporozoites and the mosquito
    Brenda Beerntsen; Fiscal Year: 2009
    ....
  17. Population genetic structure and bionomics of Anopheles lesteri in China
    Yajun Ma; Fiscal Year: 2007
    ..lesteri mosquitoes as well as the geographic variation of its bionomics. This information is particularly useful for the design of rational area-specific vector control methods. [unreadable] [unreadable]..
  18. Molecular Genetics of Dengue Resistance in Mosquitoes
    David Severson; Fiscal Year: 2008
    ..abstract_text> ..
  19. Species-specific regulated transposition in mosquitoes
    Anthony James; Fiscal Year: 2008
    ..gambiae and Ae. aegypti. ..
  20. Septate junctional proteins: Proteomic identification and role in diuresis
    KLAUS BEYENBACH; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  21. Hemocyte Transcriptome and Immunity in Aedes aegypti
    BRUCE MARTIN CHRISTENSEN; Fiscal Year: 2010
    ..All data resulting from microarray analyses, including experimental protocols used, will be made publicly available on the interactive website that contains our hemocyte EST data. ..
  22. Measuring Entomological Risk for Dengue
    THOMAS WALLACE SCOTT; Fiscal Year: 2010
    ..Our results will be relevant for dengue prevention programs based on vector control and/or vaccine strategies and will have immediate, practical applications for dengue surveillance and control worldwide. ..
  23. RECOMBINANT ANTIBODIES BLOCKING SPOROZOITE TRANSMISSION
    Anthony James; Fiscal Year: 2002
    ..The idea is that results from these research projects will be relatively easily transferred to the P. falciparum sporozoites and their vectors, anopholine mosquitoes. ..
  24. MOSQUITO IMMUNITY FUNCTIONS
    Ann Fallon; Fiscal Year: 2003
    ..The work will include identification of exon-intron organization and recovery of upstream flanking DNA, which will be analyzed for potential regulatory elements. ..
  25. RECEPTORS FROM MOSQUITO AEDES AEGYPTI EXCRETORY SYSTEM
    PATRICIA PIETRANTONIO; Fiscal Year: 2002
    ..Aegypti. To test the hypothesis, the applicant proposes to clone the receptor gene, localize the tissue expression by in situ hybridization and immunohistochemistry and express the protein in transformed cells. ..
  26. DEFENSIN GENE REGULATION AND MOSQUITO VECTOR COMPETENCE
    Bruce Christensen; Fiscal Year: 2003
    ..aegypti and Cx. pipiens. Studies with Cx. Pipiens and W. bancrofti are possible because of a collaborative arrangement with researchers in Egypt. ..
  27. GROWTH OF B MALAYI IN MURINE MODELS--ROLE OF NK CELLS
    THIRUCHANDURAI RAJAN; Fiscal Year: 2001
    ..Identification of the molecule(s) involved in the interaction could help us formulate a rationale approach to immunoprophylaxis, as well as pharmacology of lymphatic filarial parasites. ..
  28. MULTIPLE BLOOD FEEDING BY MOSQUITOES
    Thomas Scott; Fiscal Year: 2003
    ..Insecticide treatments at the end of each experiment will kill any surviving released mosquitoes before they could become infective and transmit virus. ..
  29. The Aedes aegypti Genome Project
    David Severson; Fiscal Year: 2003
    ..The long range goal is to promote and foster collaboration between funding agencies to support an effort to sequence the entire A. aegypti genome. ..
  30. IMMUNE RESPONSE OF MOSQUITOES TO FILARIAL WORMS
    Bruce Christensen; Fiscal Year: 2003
    ..abstract_text> ..
  31. SYNTHESIS AND DEGRADATION OF RIBOSOMES IN THE MOSQUITO
    Ann Fallon; Fiscal Year: 2004
    ..These studies provide cloned genes, molecular approaches, and characterization of regulatory processes that can potentially be manipulated to interfere with disease transmission by blood-feeding arthropods. ..
  32. ECDYSONE EFFECTS ON MOSQUITO CELL PROLIFERATION
    Ann Fallon; Fiscal Year: 2001
    ..Results of this study will provide novel insights into the effects of 20E on cell growth and proliferation, which are directly relevant to efforts to control vector-borne disease by genetic manipulation of insect vectors. ..
  33. RFLP MAPPING OF PLASMODIUM REFACTORY GENES IN MOSQUITOES
    David Severson; Fiscal Year: 2004
    ..abstract_text> ..
  34. ENTOMOLOGICAL ASSUMPTIONS OF DENGUE CONTROL
    Thomas Scott; Fiscal Year: 2002
    ....
  35. In vitro culture and transformation of Wolbachia from mosquitoes
    Ann Fallon; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  36. EXPRESSION OF EXOGENOUS GENES IN VECTOR MOSQUITOES
    Anthony James; Fiscal Year: 2006
    ..stephensi and An. gambiae expressing reporter genes under the control of promoters derived from genes expressed specifically in the adult female fat body cells. ..
  37. Wolbachia as an Agent for Population Replacement in Anopheles Gambiae
    Jason Rasgon; Fiscal Year: 2008
    ..We propose to evaluate transfer Wolbachia infection into Anopheles gambiae and evaluate the symbiont as a candidate transgene drive system for malaria control. [unreadable] [unreadable] [unreadable]..
  38. Development of De-immunized Botulinum Neurotoxin Type A for Dystonia
    Anne De Groot; Fiscal Year: 2008
    ..Public Health Relatedness: Knowledge of the elements of botulinum neurotoxin type A that give rise to its immunogenicity will contribute to the development of improved dystonia therapy. [unreadable] [unreadable] [unreadable]..
  39. A new family of secreted adhesive proteins in Plasmodium
    THOMAS TEMPLETON; Fiscal Year: 2008
    ....
  40. Mathematical Modeling of the Superspreaders of Antibiotic-Resistante Bacteria
    Shigui Ruan; Fiscal Year: 2010
    ..The proposed work will lead to a better understanding of the factors which contribute to the spread of ARB, and will allow the development and implementation of effective public health policies. ..
  41. ANION REGULATION IN LARVAE OF DISEASE VECTOR MOSQUITOES
    PAUL LINSER; Fiscal Year: 2009
    ..e. gut alkalinization) has important potential. ..
  42. DNA Vaccine Delivery System for Biodefense with dengue
    Alan King; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  43. Plainning malaria training in Zambia
    Thomas Eisele; Fiscal Year: 2009
    ..Tailoring a sustainable program using appropriate technology and a framework of collaboration in support of PMI activities will greatly increase the likelihood of controlling, and perhaps eventually eliminating, malaria in Zambia. ..
  44. International Leptospirosis Society Meeting 2007
    Joseph Vinetz; Fiscal Year: 2007
    ..unreadable] Outcome of the meeting will be assessed by peer-reviewed publication and trainee publication and[unreadable] career advancement. ..
  45. Genetic Manipulation of Insects
    DAVID O BROCHTA; Fiscal Year: 2004
    ..The meeting is an uncommon opportunity for graduate students and postdoctoral fellows to obtain a high level synopsis of the field of insect molecular genetics and to make important career-advancing interactions. ..
  46. Vector Population Modification Using Wolbachia Symbionts
    Stephen Dobson; Fiscal Year: 2006
    ..g., maternal transmission rates and Wolbachia effects on host fitness), simplifying discrimination between Culex infection types, and improving methods for field cage evaluation of Wolbachia control strategies. ..
  47. Epitope Driven HIV Vaccine Development
    Anne De Groot; Fiscal Year: 2005
    ..The final product of this joint effort will be a set of plasmids to be combined in an epitope-driven, oligonucleotide-based DNA cocktail vaccine for HIV. ..
  48. Conference on Cancer and Development
    Matthew Scott; Fiscal Year: 2005
    ..The meeting is especially timely given the resent explosion of information about the involvement of developmental signal transduction pathways such as EGF, Hedgehog, TGF, and Wnt in many types of human cancer. ..
  49. Polytene chromosomes of Culex pipiens mosquito complex
    Anthony Cornel; Fiscal Year: 2004
    ..p. pipiens, Cx. p. quinquefasciatus and Cx. p. molestus and 2) Determine chromosomal homologies between Cx. p. pipiens, Cx. p. quinquefasciatus and Cx. p. molestus. ..
  50. Epidemiology of Arboviral Encephalomyelitis in Houston
    Kristy Murray; Fiscal Year: 2007
    ..Her time will be directed toward completion of the specific aims of this proposal and her PhD. [unreadable] [unreadable] [unreadable]..
  51. BIOLOGY OF MALARIA SPOROZOITES IN THE MOSQUITO VECTOR
    KENNETH VERNICK; Fiscal Year: 2004
    ..By blocking gland invasion and/or enhancing destruction, it may ultimately be possible to manipulate this dynamic state to decrease natural malaria transmission. ..
  52. A GENOME-DERIVED, EPITOPE-DRIVEN TULAREMIA VACCINE
    Anne De Groot; Fiscal Year: 2005
    ..abstract_text> ..
  53. Role of cysteine proteases in malaria transmission
    KIM WILLIAMSON; Fiscal Year: 2006
    ..In addition to increasing our understanding of the genes involved, this information can be used to direct the design of cysteine protease inhibitors that will effectively block malaria transmission. ..
  54. Microarray Analysis of Leptospiral Genomes
    Joseph Vinetz; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  55. Genetics of Innate Immunity in Human Leptospirosis in Brazil
    Joseph Vinetz; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  56. A Genome-Derived, Epitope-Driven H. Pylori Vaccine
    Anne De Groot; Fiscal Year: 2006
    ..pylori disease as our correlate of efficacy. ..
  57. Nutritional Ecology of Adult Anopheles gambiae
    WOODBRIDGE FOSTER; Fiscal Year: 2006
    ..This vector species delivers malaria to most of the approximately 300- 500 million people infected worldwide, so either approach is likely to make a significant contribution. ..
  58. Leptospirosis Transmission in the Peruvian Amazon
    Joseph Vinetz; Fiscal Year: 2006
    ....
  59. 2nd Annual Vaccine Renaissance Conference, RI
    Anne De Groot; Fiscal Year: 2006
    ..More than 80 participants attended that 1st conference from the[unreadable] New England region and beyond. ..
  60. Transport Physiology of Disease Vector Mosquitoes
    William Harvey; Fiscal Year: 2007
    ..abstract_text> ..
  61. A Sindbis virus-based Vaccine Against RVFV Infection
    Ilya Frolov; Fiscal Year: 2006
    ..The study will be important for creating a general strategy for development of vaccines against emerging infections, vaccines that require fast design and large-scale production for immediate use. [unreadable] [unreadable]..
  62. Interaction of Sindbis Virus with Cellular Processes
    ILYA V FROLOV; Fiscal Year: 2010
    ..Identification of the cellular proteins that are essential for virus growth will lead to development of new antiviral therapeutic strategies. ..
  63. Container mosquitoes and microorganism productivity
    STEVEN JULIANO; Fiscal Year: 2003
    ..This research will increase our knowledge of determinants of vector mosquito production and distribution and abundance. ..
  64. Arboviral suppressors of RNA interference
    KEVIN MYLES; Fiscal Year: 2008
    ..The identification of suppressors of RNA silencing encoded in mosquito-borne virus genomes would have enormous implications for understanding the transmission of arthropod-borne viral diseases. [unreadable] [unreadable] [unreadable]..