cockroaches

Summary

Summary: Insects of the order Dictyoptera comprising several families including Blaberidae, BLATTELLIDAE, Blattidae (containing the American cockroach PERIPLANETA americana), Cryptocercidae, and Polyphagidae.

Top Publications

  1. pmc Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica
    Maria J López-Sánchez
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Valencia, Spain
    PLoS Genet 5:e1000721. 2009
  2. pmc Differences in both prevalence and titre of specific immunoglobulin E among children with asthma in affluent and poor communities within a large town in Ghana
    W Stevens
    University of Virginia Asthma and Allergic Diseases Center, Charlottesville, VA, USA
    Clin Exp Allergy 41:1587-94. 2011
  3. ncbi Neuromechanical response of musculo-skeletal structures in cockroaches during rapid running on rough terrain
    S Sponberg
    Department of Integrative Biology, University of California, Berkeley, CA 94720, USA
    J Exp Biol 211:433-46. 2008
  4. pmc Insect hygroreceptor responses to continuous changes in humidity and air pressure
    H Tichy
    Department of Neurobiology, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
    J Neurophysiol 103:3274-86. 2010
  5. pmc Death of an order: a comprehensive molecular phylogenetic study confirms that termites are eusocial cockroaches
    Daegan Inward
    Soil Biodiversity Group, Department of Entomology, The Natural History Museum, London SW7 5BD, UK
    Biol Lett 3:331-5. 2007
  6. pmc Juvenile hormone titer versus juvenile hormone synthesis in female nymphs and adults of the German cockroach, Blattella germanica
    Karl Treiblmayr
    Department of Organismic Biology, University of Salzburg, Hellbrunnerstrasse 34, A 5020 Salzburg, Austria
    J Insect Sci 6:1-7. 2006
  7. ncbi Mechanical transmission of pathogenic organisms: the role of cockroaches
    Y M Tatfeng
    Lahor Public Health and Research Centre, Benin City, Edo State, Nigeria
    J Vector Borne Dis 42:129-34. 2005
  8. ncbi Cockroach induces inflammatory responses through protease-dependent pathways
    Kota Wada
    Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan
    Int Arch Allergy Immunol 155:135-41. 2011
  9. pmc The indoor air and asthma: the role of cat allergens
    Libby A Kelly
    University of Virginia Asthma and Allergic Diseases Center, University of Virginia Health System, Charlottesville, VA 22908, USA
    Curr Opin Pulm Med 18:29-34. 2012
  10. ncbi Regulation of German cockroach extract-induced IL-8 expression in human airway epithelial cells
    K E Lee
    Department of Pediatrics and Institute of Allergy, Biomolecule Secretion Research Center, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea
    Clin Exp Allergy 37:1364-73. 2007

Detail Information

Publications329 found, 100 shown here

  1. pmc Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica
    Maria J López-Sánchez
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Valencia, Spain
    PLoS Genet 5:e1000721. 2009
    ..Here, we explain the metabolic reasons underlying the enigmatic return of cockroaches to the ancestral ammonotelic state.
  2. pmc Differences in both prevalence and titre of specific immunoglobulin E among children with asthma in affluent and poor communities within a large town in Ghana
    W Stevens
    University of Virginia Asthma and Allergic Diseases Center, Charlottesville, VA, USA
    Clin Exp Allergy 41:1587-94. 2011
    ..Reports from several African countries have noted an increasing prevalence of asthma in areas of extensive urbanization...
  3. ncbi Neuromechanical response of musculo-skeletal structures in cockroaches during rapid running on rough terrain
    S Sponberg
    Department of Integrative Biology, University of California, Berkeley, CA 94720, USA
    J Exp Biol 211:433-46. 2008
    ..We ran cockroaches over a track with randomized blocks of heights up to three times the animal's ;hip' (1...
  4. pmc Insect hygroreceptor responses to continuous changes in humidity and air pressure
    H Tichy
    Department of Neurobiology, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
    J Neurophysiol 103:3274-86. 2010
    ..Furthermore, the mechanical parameters associated with homogeneous changes in air pressure on the sensillum surface can only partially account for the responses of the moist and dry cells of both species to humidity stimulation...
  5. pmc Death of an order: a comprehensive molecular phylogenetic study confirms that termites are eusocial cockroaches
    Daegan Inward
    Soil Biodiversity Group, Department of Entomology, The Natural History Museum, London SW7 5BD, UK
    Biol Lett 3:331-5. 2007
    ..Our molecular phylogenetic analyses, the most comprehensive yet attempted, show that termites are social cockroaches, no longer meriting being classified as a separate order (Isoptera) from the cockroaches (Blattodea)...
  6. pmc Juvenile hormone titer versus juvenile hormone synthesis in female nymphs and adults of the German cockroach, Blattella germanica
    Karl Treiblmayr
    Department of Organismic Biology, University of Salzburg, Hellbrunnerstrasse 34, A 5020 Salzburg, Austria
    J Insect Sci 6:1-7. 2006
    ..At these stages, the observed disparities between synthesis and titer might be explained by differential action of degradation enzymes...
  7. ncbi Mechanical transmission of pathogenic organisms: the role of cockroaches
    Y M Tatfeng
    Lahor Public Health and Research Centre, Benin City, Edo State, Nigeria
    J Vector Borne Dis 42:129-34. 2005
    b>Cockroaches (Diploptera punctata) are basically tropical insects and will do their best to find a home that is both warm and moist. Their involvement in the transmission of tropical diseases is poorly investigated in Africa.
  8. ncbi Cockroach induces inflammatory responses through protease-dependent pathways
    Kota Wada
    Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan
    Int Arch Allergy Immunol 155:135-41. 2011
    Exposure to cockroaches is a major risk factor for asthma. Products from cockroaches may contain proteases and ligands for pattern recognition receptors...
  9. pmc The indoor air and asthma: the role of cat allergens
    Libby A Kelly
    University of Virginia Asthma and Allergic Diseases Center, University of Virginia Health System, Charlottesville, VA 22908, USA
    Curr Opin Pulm Med 18:29-34. 2012
    ..The objective is to discuss recent progress in our understanding of the role of the indoor environment in asthma, focusing on the special role of cat allergens...
  10. ncbi Regulation of German cockroach extract-induced IL-8 expression in human airway epithelial cells
    K E Lee
    Department of Pediatrics and Institute of Allergy, Biomolecule Secretion Research Center, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea
    Clin Exp Allergy 37:1364-73. 2007
    b>Cockroaches have been known as a cause of respiratory allergies such as asthma. IL-8 plays an integral role in the coordination and persistence of the inflammatory process in the chronic inflammation of the airways in asthma.
  11. pmc Mutual mate choice: when it pays both sexes to avoid inbreeding
    Mathieu Lihoreau
    UMR 6552 Ethos, CNRS Universite de Rennes 1, Campus Beaulieu, Rennes, France
    PLoS ONE 3:e3365. 2008
    ..We discuss the implications of our results in the light of inbreeding conflict models...
  12. ncbi Cockroach allergen Bla g 2: an unusual aspartic proteinase
    Sabina Wunschmann
    INDOOR Biotechnologies, Inc, Charlottesville, VA 22903, USA
    J Allergy Clin Immunol 116:140-5. 2005
    ..Bla g 2 is a potent cockroach allergen, but despite sharing sequence homology with aspartic proteinases, it contains critical amino acid substitutions that impair proteolytic activity. The biologic function of Bla g 2 remains unclear...
  13. pmc CYP15A1, the cytochrome P450 that catalyzes epoxidation of methyl farnesoate to juvenile hormone III in cockroach corpora allata
    C Helvig
    Department of Entomology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 101:4024-9. 2004
    ..Heterologously expressed CYP15A1 from D. punctata or its ortholog from economically important species may be useful in the design and screening of selective insect control agents...
  14. pmc Mechanical transmission of human protozoan parasites by insects
    Thaddeus K Graczyk
    Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Clin Microbiol Rev 18:128-32. 2005
    ..travel between filth and food make some groups of synanthropic insects such as nonbiting flies and cockroaches efficient vectors of human enteric protozoan parasites...
  15. pmc Crystal structure of a dimerized cockroach allergen Bla g 2 complexed with a monoclonal antibody
    Mi Li
    Macromolecular Crystallography Laboratory, NCI Frederick, National Institutes of Health, Frederick, Maryland 21702, USA
    J Biol Chem 283:22806-14. 2008
    ..We have now identified key residues involved in IgE antibody binding; this information will be useful for the design of vaccines for immunotherapy...
  16. pmc Identifying genes related to choriogenesis in insect panoistic ovaries by Suppression Subtractive Hybridization
    Paula Irles
    Institut de Biologia Evolutiva UPF CSIC, Passeig Maritim de la Barceloneta, Barcelona, Spain
    BMC Genomics 10:206. 2009
    ..To this end, we planned the construction of a Suppression Subtractive Hybridization (SSH) library to identify genes involved in panoistic choriogenesis, using the cockroach Blattella germanica as model...
  17. ncbi Overexpression of the cytochrome c oxidase subunit I gene associated with a pyrethroid resistant strain of German cockroaches, Blattella germanica (L.)
    Julia W Pridgeon
    Department of Entomology and Plant Pathology, 301 Funchess Hall, Auburn University, Auburn, AL 36849 5413, USA
    Insect Biochem Mol Biol 33:1043-8. 2003
    ..The overexpression of COXI in resistant German cockroaches merits the investigation of the importance of the gene in insecticide resistant German cockroaches.
  18. ncbi Dynamics of rapid vertical climbing in cockroaches reveals a template
    Daniel I Goldman
    Department of Integrative Biology, University of California, Berkeley, CA 94720 3140, USA
    J Exp Biol 209:2990-3000. 2006
    Rapid, vertically climbing cockroaches produced climbing dynamics similar to geckos, despite differences in attachment mechanism, ;foot or toe' morphology and leg number...
  19. ncbi Cockroach allergen exposure and sensitization in suburban middle-class children with asthma
    Elizabeth C Matsui
    Department of Pediatrics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, USA
    J Allergy Clin Immunol 112:87-92. 2003
    ..Exposure to cockroach allergen is prevalent in inner-city homes and is associated with an increased risk of cockroach sensitization...
  20. ncbi Allergenicity of sigma and delta class glutathione S-transferases from the German cockroach
    Kyoung Yong Jeong
    Department of Environmental Medical Biology and Institute of Tropical Medicine, Arthropods of Medical Importance Resource Bank, Yonsei University College of Medicine, Seoul, Korea
    Int Arch Allergy Immunol 148:59-64. 2009
    ..Cockroach glutathione S-transferases (GSTs) are known to elicit strong IgE responses. This study was undertaken to compare the IgE reactivity of German cockroach GSTs, Bla g 5 (sigma class) and delta class GST (BgGSTD1)...
  21. ncbi Role of cockroach proteases in allergic disease
    Kristen Page
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave ML7006, Cincinnati, OH, USA
    Curr Allergy Asthma Rep 12:448-55. 2012
    ..activated receptor (PAR)-2 has been implicated as a mechanism behind the potent allergenicity associated with cockroaches. In this review, we focus on recent evidence linking cockroach proteases to activation of a variety of cells ..
  22. ncbi Cockroach allergen Per a 7 down-regulates expression of Toll-like receptor 9 and IL-12 release from P815 cells through PI3K and MAPK signaling pathways
    Haiwei Yang
    Clinical Research Centre, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
    Cell Physiol Biochem 29:561-70. 2012
    ..However, influence of specific cockroach allergen on Th1 cytokine release and expression of TLR9 in mast cells remains uninvestigated...
  23. ncbi Structures of two major allergens, Bla g 4 and Per a 4, from cockroaches and their IgE binding epitopes
    Yih Wan Tan
    Department of Biological Sciences, National University of Singapore, Singapore
    J Biol Chem 284:3148-57. 2009
    Inhalant allergens from cockroaches are an important cause of asthma to millions of individuals worldwide...
  24. pmc Sensitization to cockroach allergen: immune regulation and genetic determinants
    Peisong Gao
    Department of Medicine, Johns Hopkins Asthma and Allergy Center, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Clin Dev Immunol 2012:563760. 2012
    ..In this review, we have focused on studies on the cockroach allergen induced immunologic responses and genetic basis for cockroach sensitization...
  25. pmc Chromosome stability and gene loss in cockroach endosymbionts
    Zakee L Sabree
    Center for Insect Science, University of Arizona, Tucson, Arizona 85721, USA
    Appl Environ Microbiol 76:4076-9. 2010
    ..We speculate that distant homologs may replace the functions of some eliminated genes through broadened substrate specificity...
  26. pmc Sex-stratified linkage analysis identifies a female-specific locus for IgE to cockroach in Costa Ricans
    Gary M Hunninghake
    Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Respir Crit Care Med 177:830-6. 2008
    ..The basis for gender influences on allergen-specific IgEs is unclear...
  27. pmc CD14, a key candidate gene associated with a specific immune response to cockroach
    P Gao
    Department of Medicine, Division of Allergy and Clinical Immunology, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD, USA
    Clin Exp Allergy 40:1353-64. 2010
    ..Sensitization to cockroach allergen is one of the strongest predictors of asthma morbidity, especially among African Americans...
  28. ncbi Conservation of fruitless' role as master regulator of male courtship behaviour from cockroaches to flies
    Elke Clynen
    Institute of Evolutionary Biology CSIC UPF, Passeig Maritim de la Barceloneta 37, 08003, Barcelona, Spain
    Dev Genes Evol 221:43-8. 2011
    ..This suggests that the role of fruitless as master regulator of male sexual behaviour has been conserved along insect evolution, at least from cockroaches to flies.
  29. pmc Group living enhances individual resources discrimination: the use of public information by cockroaches to assess shelter quality
    Stéphane Canonge
    Unit of Social Ecology, Universite Libre de Bruxelles ULB, Brussels, Belgium
    PLoS ONE 6:e19748. 2011
    ..Using binary choice between sheltering sites of different quality, we demonstrate that cockroaches in group dramatically outperform the problem-solving ability of single individual...
  30. pmc The bacterial community in the gut of the Cockroach Shelfordella lateralis reflects the close evolutionary relatedness of cockroaches and termites
    Christine Schauer
    Department of Biogeochemistry, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany
    Appl Environ Microbiol 78:2758-67. 2012
    Termites and cockroaches are closely related, with molecular phylogenetic analyses even placing termites within the radiation of cockroaches...
  31. ncbi Design, synthesis and biological activity of peptidomimetic analogs of insect allatostatins
    Yong Xie
    Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, PR China
    Peptides 32:581-6. 2011
    Allatostatins (ASTs) comprise a family of insect neuropeptides isolated from cockroaches and found to inhibit the production of juvenile hormone (JH) by the corpora allata (CA)...
  32. ncbi Sodium channel gene expression associated with pyrethroid resistant house flies and German cockroaches
    Qiang Xu
    Department of Entomology and Plant Pathology, Auburn University, Auburn, AL 36849 5413, USA
    Gene 379:62-7. 2006
    ..These results suggest a role for posttranscriptional regulation in the connection of the sodium channel genotype and its mutation-mediated resistance phenotype...
  33. ncbi Classical olfactory conditioning in the cockroach Periplaneta americana
    Hidehiro Watanabe
    Graduate School of Life Sciences, Tohoku University, Sendai, Japan
    Zoolog Sci 20:1447-54. 2003
    ..b>Cockroaches underwent differential conditioning trials in which peppermint odor was associated with sucrose solution and ..
  34. pmc Genome economization in the endosymbiont of the wood roach Cryptocercus punctulatus due to drastic loss of amino acid synthesis capabilities
    Alexander Neef
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Spain
    Genome Biol Evol 3:1437-48. 2011
    b>Cockroaches (Blattaria: Dictyoptera) harbor the endosymbiont Blattabacterium sp. in their abdominal fat body. This endosymbiont is involved in nitrogen recycling and amino acid provision to its host...
  35. ncbi Eotaxin represents the principal eosinophil chemoattractant in a novel murine asthma model induced by house dust containing cockroach allergens
    J Kim
    Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    J Immunol 167:2808-15. 2001
    ....
  36. ncbi Cockroach allergens and asthma
    L K Arruda
    Departments of Pediatrics and Cell and Molecular Biology, , Brazil
    J Allergy Clin Immunol 107:419-28. 2001
    ..Structural homology between tropomyosins from cockroaches, mites, and shrimp may explain clinical cases of the oral allergy syndrome...
  37. ncbi Evidence for a role of orcokinin-related peptides in the circadian clock controlling locomotor activity of the cockroach Leucophaea maderae
    Sabine Hofer
    Fachbereich Biologie, Tierphysiologie, Philipps Universitat Marburg, D 35032 Marburg, Germany
    J Exp Biol 209:2794-803. 2006
    ..This study, furthermore, provides the first evidence for a physiological role of an orcokinin-related peptide in insects...
  38. pmc Early immunological response to German cockroach frass exposure induces a Th2/Th17 environment
    Kristen Page
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center and Cincinnati Children s Research Foundation, Ohio 45229, USA
    J Innate Immun 3:167-79. 2011
    ..Together, our data show that GC frass activated the innate immune response to augment DC recruitment and activation of mDCs which promoted robust T cell-skewing cytokines and ultimately drive the development of airway inflammation...
  39. pmc Differences in susceptibility to German cockroach frass and its associated proteases in induced allergic inflammation in mice
    Kristen Page
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Respir Res 8:91. 2007
    ..Cockroach exposure is a major risk factor for the development of asthma. Inhalation of fecal remnants (frass) is the likely sensitizing agent; however isolated frass has not been tested for its ability to induce experimental asthma in mice...
  40. pmc Oral tolerance inhibits pulmonary eosinophilia in a cockroach allergen induced model of asthma: a randomized laboratory study
    Louis J Vaickus
    Boston University School of Medicine, Department of Pathology and Laboratory Medicine, Boston, MA, USA
    Respir Res 11:160. 2010
    ..In this study we endeavored to induce oral tolerance to cockroach allergen (CRA: a complex mixture of insect components) in order to ameliorate asthma-like, allergic pulmonary inflammation...
  41. ncbi Specific IgE and IgG antibody-binding patterns to recombinant cockroach allergens
    Shama M Satinover
    Asthma and Allergic Diseases Center, University of Virginia Health System, Charlottesville, VA 22908 1355, USA
    J Allergy Clin Immunol 115:803-9. 2005
    ..The specificity of serum antibody responses to different cockroach allergens has not been studied...
  42. pmc Deficiency of regulatory B cells increases allergic airway inflammation
    S K Lundy
    Department of Internal Medicine Rheumatology, University of Michigan Medical School, Ann Arbor, 48109, USA
    Inflamm Res 54:514-21. 2005
    ..To investigate the effect of the X-linked immunodeficiency (Xid) B cell defect on the response to the cockroach allergen in mice...
  43. ncbi Octopamine-like immunoreactivity in the honey bee and cockroach: comparable organization in the brain and subesophageal ganglion
    Irina Sinakevitch
    Arizona Research Laboratories, Division of Neurobiology, University of Arizona, Tucson, Arizona 85721, USA
    J Comp Neurol 488:233-54. 2005
    A serum raised against octopamine reveals in cockroaches and honey bees structurally comparable systems of perikarya and their extensive yet discrete systems of arborizations in neuropils...
  44. ncbi House dust mite and cockroach exposure are strong risk factors for positive allergy skin test responses in the Childhood Asthma Management Program
    K Huss
    Johns Hopkins Asthma and Allergy Center, Baltimore, MD, USA
    J Allergy Clin Immunol 107:48-54. 2001
    ..sensitivities to house dust mites (Dermatophagoides farinae and Dermatophagoides pteronyssinus), cats, dogs, cockroaches, and molds were examined for relationships to demographic variables, home dust allergen exposures, number of ..
  45. ncbi Non-synaptic ion channels in insects--basic properties of currents and their modulation in neurons and skeletal muscles
    D Wicher
    Sachsische Akademie der Wissenschaften zu Leipzig, Arbeitsgruppe Neurohormonale Wirkungsmechanismen, Erbertstr 1, 07743, Jena, Germany
    Prog Neurobiol 64:431-525. 2001
    ..Further study of their effects on the single cell level should help to understand how small sets of cells cooperate in order to produce the appropriate output...
  46. ncbi Results of a home-based environmental intervention among urban children with asthma
    Wayne J Morgan
    Arizona Respiratory Center, University of Arizona, 1501 N Campbell Ave, Tucson, AZ 85724, USA
    N Engl J Med 351:1068-80. 2004
    ..The objective of this study was to determine whether an environmental intervention tailored to each child's allergic sensitization and environmental risk factors could improve asthma-related outcomes...
  47. pmc Reproductive aging and mating: the ticking of the biological clock in female cockroaches
    P J Moore
    School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, United Kingdom
    Proc Natl Acad Sci U S A 98:9171-6. 2001
    ..Our results further suggest that selection for continued choosiness is also relaxed and supports direct selection on female choosiness and a cost to choosiness...
  48. ncbi Respiratory syncytial virus-induced exaggeration of allergic airway disease is dependent upon CCR1-associated immune responses
    Alison E John
    Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109 0602, USA
    Eur J Immunol 35:108-16. 2005
    ....
  49. pmc Socioeconomic predictors of high allergen levels in homes in the greater Boston area
    B T Kitch
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Environ Health Perspect 108:301-7. 2000
    ..Within a single U.S. metropolitan area we found marked between-community differences in the types of allergens present in the home, but not necessarily in the overall burden of allergen exposure...
  50. ncbi Monocyte chemoattractant protein-1 mediates cockroach allergen-induced bronchial hyperreactivity in normal but not CCR2-/- mice: the role of mast cells
    E M Campbell
    Department of Pathology, Division of Pulmonary and Critical Care, University of Michigan Medical School, Ann Arbor 48109, USA
    J Immunol 163:2160-7. 1999
    ..Thus, these data identify MCP-1 and CCR2 as potentially important therapeutic targets for the treatment of hyperreactive airway disease...
  51. pmc Enzymatic activities of allergen extracts from three species of dust mites and cockroaches commonly found in Korean home
    Kyoung Yong Jeong
    Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120 752, Korea
    Korean J Parasitol 48:151-5. 2010
    Allergen extracts from dust mites and cockroaches commonly found in Korean homes were used to evaluate their enzymatic activity as they are believed to influence allergenicity...
  52. pmc Cockroaches keep predators guessing by using preferred escape trajectories
    Paolo Domenici
    Istituto per l Ambiente Marino Costiero, Consiglio Nazionale delle Ricerche, Localita Sa Mardini, 09072 Torregrande Oristano, Italy
    Curr Biol 18:1792-6. 2008
    ..However, the rules governing this variability are largely unknown. Here, we demonstrate that individual cockroaches (Periplaneta americana, a much-studied model prey species [9-14]) keep each escape unpredictable by running ..
  53. pmc A genomewide search for quantitative-trait loci underlying asthma
    X Xu
    Program for Population Genetics, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Hum Genet 69:1271-7. 2001
    ..No significant or suggestive evidence of linkage for the other four traits was found...
  54. ncbi CD8+ T cell contributions to allergen induced pulmonary inflammation and airway hyperreactivity
    Matthew A Schaller
    Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109 0602, USA
    Eur J Immunol 35:2061-70. 2005
    ..Altogether, these studies highlight a role for CD8(+) T lymphocytes in the development of allergen-induced airway responses...
  55. ncbi Complete mitochondrial genomes of two cockroaches, Blattella germanica and Periplaneta americana, and the phylogenetic position of termites
    Bo Xiao
    Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Wenyuan Road 1, Nanjing 210046, China
    Curr Genet 58:65-77. 2012
    ..However, the closely related termites (Isoptera) are retained as unranked taxon within the order Blattaria (cockroaches)...
  56. ncbi Multidrug resistant bacteria isolated from cockroaches in long-term care facilities and nursing homes
    Hsiu Hua Pai
    Department of Kinesiology, Health, and Leisure Studies, National University of Kaohsiung, No 700, Kaohsiung University Road, Nan Tzu District, Kaohsiung 811, Taiwan, ROC
    Acta Trop 125:18-22. 2013
    ..The nocturnal and filthy habits of cockroaches may be ideal disseminators of pathogenic microorganisms in these institutions...
  57. ncbi The fine structure of colleterial glands in two cockroaches and three termites, including a detailed study of Cryptocercus punctulatus (Blattaria, Cryptocercidae) and Mastotermes darwiniensis (Isoptera, Mastotermitidae)
    Annie Courrent
    UMR CNRS 5548, Développement et Communication Chimique chez les Insectes, Universite de Bourgogne, 21000 Dijon, France
    Arthropod Struct Dev 37:55-66. 2008
    The colleterial glands of insects are organs associated with the female genital apparatus. In cockroaches, these glands produce secretions that cover two parallel rows of eggs during oviposition, and in oviparous species, these ..
  58. ncbi Spatial learning in the restrained American cockroach Periplaneta americana
    Hyung Wook Kwon
    Dept of Biological Sciences, 6270 Medical Research Building III, Vanderbilt University, 465 21st Avenue South, Nashville, TN 37235, USA
    J Exp Biol 207:377-83. 2004
    Spatial learning abilities were tested in restrained cockroaches by observing antennal projection responses towards the positions of a learned visual cue perceived monocularly by one eye in the context of a second stimulus provided to ..
  59. ncbi Cockroach allergen Bla g 2: structure, function, and implications for allergic sensitization
    Anna Pomes
    Asthma and Allergic Diseases Center, Department of Internal Medicine, University of Virginia Health System, Charlottesville, VA, 22903, USA
    Am J Respir Crit Care Med 165:391-7. 2002
    ..The results show dissociation between enzymatic activity and allergenicity for Bla g 2 and suggest that other genetic and environmental factors are important determinants of sensitization...
  60. ncbi Direct injection of venom by a predatory wasp into cockroach brain
    Gal Haspel
    Zlotowski Center for Neuroscience and Department of Life Sciences, Ben Gurion University, Beer Sheva, Israel
    J Neurobiol 56:287-92. 2003
    ..To our knowledge, this is the first direct evidence documenting targeted delivery of venom by a predator into the brain of its prey...
  61. ncbi Detecting substrate engagement: responses of tarsal campaniform sensilla in cockroaches
    Sasha N Zill
    Department of Anatomy and Pathology, Joan C Edwards School of Medicine, Marshall University, Huntington, WV 25704, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 196:407-20. 2010
    ..responses of campaniform sensilla, receptors that encode forces as cuticular strains, in the tarsi (feet) of cockroaches using neurophysiological techniques and digital imaging...
  62. ncbi Light-mimicking cockroaches indicate Tertiary origin of recent terrestrial luminescence
    Peter Vršanský
    Geological Institute, Slovak Academy of Sciences, Dubravska cesta 9, P O Box 106, 840 05, Bratislava, Slovakia
    Naturwissenschaften 99:739-49. 2012
    ..Here, we present a geographical distribution of only the third order of luminescent insects--luminescent cockroaches, with all 13 known and/or herein reported new living species (based on deposited specimens)...
  63. ncbi Tuning posture to body load: decreases in load produce discrete sensory signals in the legs of freely standing cockroaches
    Bridget R Keller
    Department of Anatomy and Pathology, Joan C Edwards School of Medicine, Marshall University, Huntington, WV 25704, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 193:881-91. 2007
    ..sensilla, receptors that monitor forces as strains in the exoskeleton, in the middle legs of freely moving cockroaches. Small magnets were attached to the thorax and body load was changed by applying currents to a coil below the ..
  64. ncbi Context-dependent olfactory learning monitored by activities of salivary neurons in cockroaches
    Chihiro Sato Matsumoto
    Graduate School of Life Sciences, Tohoku University, Sendai 980 8577, Japan
    Neurobiol Learn Mem 97:30-6. 2012
    ..problem solving) of salivation, which can be monitored as activity changes of salivary neurons in immobilized cockroaches, Periplaneta americana...
  65. pmc Cross-epithelial hydrogen transfer from the midgut compartment drives methanogenesis in the hindgut of cockroaches
    T Lemke
    Fachbereich Biologie, LS Mikrobielle Okologie, , 78457 Konstanz, Germany
    Appl Environ Microbiol 67:4657-61. 2001
    ..1 kPa) in the posterior hindgut. Moreover, living cockroaches emitted large quantities of CH(4) [105 +/- 49 nmol (g of cockroach)(-1) h(-1)] but only traces of H(2)...
  66. ncbi Occupational health risks due to shipboard cockroaches
    Marcus Oldenburg
    Department of Maritime Medicine, Institute of Occupational and Maritime Medicine ZfAM, University of Hamburg, Seewartenstrasse 10, 20459 Hamburg, Germany
    Int Arch Occup Environ Health 81:727-34. 2008
    In various investigated populations, sensitization to cockroaches was observed in 8% of screened subjects from temperate climatic zones and in 36% of those from tropical zones...
  67. ncbi Cockroach allergen biology and mitigation in the indoor environment
    J Chad Gore
    Department of Entomology, North Carolina State University, Raleigh, North Carolina 27695 7613, USA
    Annu Rev Entomol 52:439-63. 2007
    For nearly a half century, cockroaches have been recognized as a major cause of asthma morbidity in the urban, inner-city environment...
  68. pmc Circadian regulation of insect olfactory learning
    Susan Decker
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA
    Proc Natl Acad Sci U S A 104:15905-10. 2007
    ..odor preference was tested by allowing animals to choose between two odors (peppermint and vanilla), untrained cockroaches showed a clear preference for vanilla at all circadian phases, indicating that there was no circadian ..
  69. ncbi Bacterial, fungal and parasitic contamination of cockroaches in public hospitals of Hamadan, Iran
    A Salehzadeh
    Department of Environmental Health, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran
    J Vector Borne Dis 44:105-10. 2007
    To determine the possible role of cockroaches in dissemination of medically important microorganisms, a study was carried out in public hospitals and residential areas of Hamadan city, west of Iran...
  70. ncbi German cockroach extract increases bronchial epithelial cell interleukin-8 expression
    R K Bhat
    Department of Pediatrics, University of Chicago, Chicago, Illinois, USA
    Clin Exp Allergy 33:35-42. 2003
    ..While dust mite and Aspergillus fumigatus aeroallergens have been noted to have direct effects on airway epithelium, direct effects of cockroach proteins have not been determined...
  71. ncbi Evolution and phylogenetic information content of the ribosomal DNA repeat unit in the Blattodea (Insecta)
    Dmitrv Mukha
    Vavilov Institute of General Genetics, Russian Academy of Sciences, Gubkin St 3, 117809, Moscow, Russia
    Insect Biochem Mol Biol 32:951-60. 2002
    ..and nucleotide variability of the ribosomal repeat unit was compared among families, genera, and species of cockroaches (Insecta:Blattodea)...
  72. ncbi Characterization and partial purification of the cockroach antigen in relation to housedust and housedust mite (D.f.) antigens
    B C Kang
    Department of Medicine, Mount Sinai Hospital, Chicago, IL 60608
    Ann Allergy 63:207-12. 1989
    ..B2, the low molecular fraction (molecular weight less than 13,000 dalton) contained minor allergen(s). B2 elicited positive AST in 55% of cockroach-sensitive individuals, but it was not detected by IEP, CIE, nor by DID...
  73. ncbi Cockroaches breathe discontinuously to reduce respiratory water loss
    Natalie G Schimpf
    School of Biological Sciences, Faculty of Biological and Chemical Sciences, University of Queensland, Brisbane 4000, Australia
    J Exp Biol 212:2773-80. 2009
    ..Adult cockroaches (Nauphoeta cinerea) were chronically exposed to various treatments of different respiratory gas compositions (O(..
  74. ncbi Cockroaches (Periplaneta americana and Blattella germanica) as potential vectors of the pathogenic bacteria found in nosocomial infections
    M R Fakoorziba
    Department of Medical Entomology, Research Centre for Health Sciences, Shiraz University of Medical Sciences, Iran
    Ann Trop Med Parasitol 104:521-8. 2010
    Although it has been difficult to prove the direct involvement of cockroaches (i.e...
  75. ncbi Cockroaches that exchange respiratory gases discontinuously survive food and water restriction
    Natalie G Schimpf
    School of Biological Sciences, The University of Queensland, St Lucia 4072, Australia
    Evolution 66:597-604. 2012
    ..We show that metabolic rate has no effect on survival during food and water restriction, but cockroaches exhibiting discontinuous gas exchange cycles (DGCs) live longer than those that do not and those provisioned ..
  76. ncbi Suppression of JH biosynthesis by JH analog treatment: mechanism of suppression and roles of allatostatins and nervous connections in the cockroach Diploptera punctata
    Lisa E Lenkic
    Dept of Cell and Systems Biology, University of Toronto, Toronto ON, Canada
    J Insect Physiol 55:967-75. 2009
    ....
  77. ncbi Synthesis, biological activity, and hologram quantitative structure-activity relationships of novel allatostatin analogues
    Zhen peng Kai
    Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, People s Republic of China
    J Agric Food Chem 58:2652-8. 2010
    ..These results will be useful in the design of new AST analogues that are structurally related to the training set compounds...
  78. ncbi A potential insect growth regulator: synthesis and bioactivity of an allatostatin mimic
    Zhen peng Kai
    Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, 100193, PR China
    Peptides 30:1249-53. 2009
    ..H17 also shows a highly significant inhibition of JH production in topical cuticular assays in vivo. Our results suggest that H17 has potential as an IGR for cockroach control...
  79. ncbi Identification of mariner elements from house flies (Musca domestica) and German cockroaches (Blattella germanica)
    N Liu
    Department of Entomology and Plant Pathology, Auburn University, AL, USA
    Insect Mol Biol 13:443-7. 2004
    Full-length mariner elements were isolated and sequenced from house flies (Musca domestica) and German cockroaches (Blattella germanica). The amino acid sequence of the house fly mariner element (accession number: AF373028) showed 99...
  80. ncbi Indoor allergen sensitization and the risk of asthma and eczema in children in Pittsburgh
    Brook M McHugh
    Division of Pulmonary Medicine, Allergy and Immunology, Children s Hospital of Pittsburgh of UPMC, Department of Pediatrics, University of Pittsburgh School of Medicine, Pennsylvania, USA
    Allergy Asthma Proc 32:372-6. 2011
    ..Asthma and eczema are not significantly more frequent among children who had positive skin testing to cockroaches or mice...
  81. pmc Mucosal sensitization to German cockroach involves protease-activated receptor-2
    Kristen Page
    Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA
    Respir Res 11:62. 2010
    ..The role for PAR-2 in mediating allergic airway inflammation has not been assessed using a real world allergen...
  82. pmc Reproducibility of a novel model of murine asthma-like pulmonary inflammation
    L McKinley
    Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Clin Exp Immunol 136:224-31. 2004
    ..This study shows that HDE containing high levels of cockroach allergens and endotoxin collected from different sources can induce an asthma-like response in our murine model...
  83. pmc Coevolution between a cockroach and its bacterial endosymbiont: a biogeographical perspective
    J W Clark
    Department of Entomology, Kansas State University, Manhattan 66506, USA
    Proc Biol Sci 268:393-8. 2001
    Cryptocercus are subsocial, xylophagous cockroaches that live in temperate forests. Like other cockroaches, Cryptocercus harbour endosymbiotic bacteria in their fat bodies...
  84. ncbi Sensitization to common allergens, especially pollens, among children with respiratory allergy in the Trakya region of Turkey
    Mehtap Yazicioglu
    Trakya University Faculty of Medicine, Department of Pediatrics, Trakya, Turkey
    Asian Pac J Allergy Immunol 22:183-90. 2004
    ..Although Trakya is close to Greece and other Mediterranean countries, this study suggests that the pollens, which sensitize children, are not similar...
  85. ncbi Phylogeny of endosymbiont bacteria harbored by the woodroach Cryptocercus spp. (Cryptocercidae: Blattaria): molecular clock evidence for a late Cretaceous--early Tertiary split of Asian and American lineages
    Kiyoto Maekawa
    Department of Biology, Toyama University, 3190 Gofuku, Toyama 930 8555, Japan
    Mol Phylogenet Evol 36:728-33. 2005
  86. pmc Reducing LPS content in cockroach allergens increases pulmonary cytokine production without increasing inflammation: a randomized laboratory study
    Sudha Natarajan
    Department of Pathology and Laboratory Medicine, Boston University School of Medicine, 670 Albany Street, 720 Harisson Avenue, Boston, MA 02118, USA
    BMC Pulm Med 11:12. 2011
    ....
  87. pmc Cockroaches that lack Blattabacterium endosymbionts: the phylogenetically divergent genus Nocticola
    Nathan Lo
    School of Biological Sciences, The University of Sydney, Sydney, New South Wales 2006, Australia
    Biol Lett 3:327-30. 2007
    ..to amplify 16S rRNA from the obligate mutualistic endosymbiont Blattabacterium cuenoti, present in all cockroaches studied to date. Unexpectedly, amplification was unsuccessful in all Nocticola spp. examined...
  88. pmc Neighborhood differences in exposure and sensitization to cockroach, mouse, dust mite, cat, and dog allergens in New York City
    Omar Olmedo
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Allergy Clin Immunol 128:284-292.e7. 2011
    ..Asthma prevalence varies widely among neighborhoods within New York City. Exposure to mouse and cockroach allergens has been suggested as a cause...
  89. ncbi Flagellated protozoa in cockroaches and sputum: the unhygienic connection?
    Rafael Martinez-Giron
    Allergy Asthma Proc 28:608-9. 2007
  90. ncbi Wood-feeding cockroaches as models for termite evolution (Insecta: Dictyoptera): Cryptocercus vs. Parasphaeria boleiriana
    Klaus Dieter Klass
    State Natural History Collections Dresden, Museum of Zoology, Königsbrücker Landstrasse 159, D 01109 Dresden, Germany
    Mol Phylogenet Evol 46:809-17. 2008
    Isoptera are highly specialized cockroaches and are one of the few eusocial insect lineages...
  91. pmc Maternal investment affects offspring phenotypic plasticity in a viviparous cockroach
    Glenn L Holbrook
    Department of Entomology, W M Keck Center for Behavioral Biology, North Carolina State University, Box 7613, Raleigh, NC 27695 7613, USA
    Proc Natl Acad Sci U S A 101:5595-7. 2004
    ..By investing more in each offspring, however, D. punctata mothers, because they are viviparous, are able to produce broods with environmentally (socially) independent phenotypes...
  92. pmc Biochemical characterization and ultrastructural localization of two extracellular trypsins produced by Metarhizium anisopliae in infected insect cuticles
    R J St Leger
    Boyce Thompson Institute, Cornell University, Ithaca, New York 14853, USA
    Appl Environ Microbiol 62:1257-64. 1996
    ..The extracellular sheath, which is commonly observed around fungal cells, often contained Pr2 molecules. Intracellular labelling was sparse...
  93. ncbi Orcokinin immunoreactivity in the accessory medulla of the cockroach Leucophaea maderae
    Sabine Hofer
    Fachbereich Biologie, Tierphysiologie, Philipps Universitat Marburg, 35032 Marburg, Germany
    Cell Tissue Res 325:589-600. 2006
    ..Immunostaining in the ventromedian neurons suggests that orcokinin-related peptides play a role in the heterolateral transmission of photic input to the pacemaker and/or in the coupling of the bilateral pacemakers of the cockroach...
  94. ncbi Anatomy and physiology of neurons with processes in the accessory medulla of the cockroach Leucophaea maderae
    R Loesel
    Fachbereich Biologie/Tierphysiologie, , D-35032 Marburg, Germany
    J Comp Neurol 439:193-207. 2001
    ..Finally, neurons responding to movement stimuli did not arborize in the AMe. The results show that the AMe receives photic input and support a role of this neuropil in circadian timekeeping functions...
  95. ncbi Baratin, a nonamidated neurostimulating neuropeptide, isolated from cockroach brain: distribution and actions in the cockroach and locust nervous systems
    D R Nässel
    Department of Zoology, Stockholm University, S 10691 Stockholm, Sweden
    J Comp Neurol 422:267-86. 2000
    ..When baratin (10(-6)-10(-4) M) was applied to desheathed abdominal ganglia of locusts and cockroaches, we could monitor bursts of action potentials in neurons with axons in the anterior abdominal nerve (nerve 1), ..
  96. ncbi Ultrastructure of pigment-dispersing hormone-immunoreactive neurons in a three-dimensional model of the accessory medulla of the cockroach Leucophaea maderae
    Thomas Reischig
    Department of Biology, Institute of Animal Physiology, Philipps University Marburg, Karl von Frisch Strasse, 35032 Marburg, Germany
    Cell Tissue Res 314:421-35. 2003
    ..The small, weakly staining anterior PDHMe belong to a morphological group different from the large and medium-sized PDHMe and cannot be further identified at the electron-microscopic level because of their weak PDH immunoreactivity...
  97. ncbi Ectopic transplantation of the accessory medulla restores circadian locomotor rhythms in arrhythmic cockroaches (Leucophaea maderae)
    Thomas Reischig
    Biology, Animal Physiology, Philipps Universitat Marburg, Karl von Frisch Strasse, D 35041 Marburg, Germany
    J Exp Biol 206:1877-86. 2003
    ..Here, we demonstrate that ectopic transplantation of adult accessory medulla into optic lobe-less cockroaches restores circadian locomotor activity rhythms in L. maderae...
  98. ncbi Pigment-dispersing hormone (PDH)-immunoreactive neurons form a direct coupling pathway between the bilaterally symmetric circadian pacemakers of the cockroach Leucophaea maderae
    Thomas Reischig
    Department of Neurobiology, Institute of Zoology and Anthropology, Georg August University of Gottingen, Berliner Strasse 28, 37073, Gottingen, Germany
    Cell Tissue Res 318:553-64. 2004
    ..Thus, anterior PDHMe neurons seem to play multiple roles in generating circadian rhythms. They also deliver timing information output and perform mutual pacemaker coupling in L. maderae...
  99. ncbi Molecular evidence and phylogenetic affiliations of Wolbachia in cockroaches
    Parag A Vaishampayan
    National Centre for Cell Science, University of Pune, Ganeshkhind, Pune 411007, India
    Mol Phylogenet Evol 44:1346-51. 2007
  100. pmc Prediction of residential pet and cockroach allergen levels using questionnaire information
    Ulrike Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Environ Health Perspect 112:834-9. 2004
    We assessed the accuracy of questionnaire reports of cat and dog ownership and presence of cockroaches in predicting measured allergen concentrations in house dust...
  101. ncbi Implementation of pigment-dispersing factor-immunoreactive neurons in a standardized atlas of the brain of the cockroach Leucophaea maderae
    Hongying Wei
    Animal Physiology, FB18, University of Kassel, Kassel, Germany
    J Comp Neurol 518:4113-33. 2010
    ..The distances between PDF-ir branching areas show specific numerical relationships that might be physiologically relevant for temporal encoding...

Research Grants65

  1. ASTHMA AND ALLERGIC DISEASE CENTER
    Thomas A Platts Mills; Fiscal Year: 2010
    ..The overall objective is to understand the effects of obesity, physical activity and allergic sensitization in relation to symptoms of breathlessness and airway obstruction. ..
  2. Eosinophil ORMDL3 and allergic inflammation
    P Sriramarao; Fiscal Year: 2012
    ....
  3. Environmental Chitin Exposure in the Pathogenesis of Asthma
    Rene M Roy; Fiscal Year: 2012
    ..to common environmental allergens along with respiratory allergies to house dust mites, fungal spores, and cockroaches are risk factors in the development of asthma...
  4. Development and validation of a chitin assay for environmental samples
    CHRISTINE ANNE ROGERS; Fiscal Year: 2012
    ..and is a structural component of common indoor organisms such as dust mites, cockroaches, and fungi that are known asthma triggers...
  5. DUST MITE, COCKROACH AND CAT ALLERGENS IN ASTHMA
    Thomas A Platts-Mills; Fiscal Year: 2013
    ....
  6. Antigenic determinants of asthma-associated allergens for design of immunotherapy
    Anna Pomes; Fiscal Year: 2012
    ..Hypoallergenic mutants will be produced and tested for IgE antibody binding and T cell proliferation, and the information obtained will facilitate a rational design of allergy vaccines. ..
  7. Sensitization to Cockroach Allergen: Immune Regulation and Genetic Determinants
    Peisong Gao; Fiscal Year: 2013
    ..This will provide novel insights into the role of cockroach allergen-CD206 axis in the pathogenesis of allergic diseases and offer an opportunity for novel therapies. ..
  8. Genes, Home Allergens and Asthma in Puerto Rican Children
    JUAN CARLOS CELEDON; Fiscal Year: 2010
    ..This application will contribute greatly to our understanding of asthma in general, and among Puerto Ricans in particular. ..
  9. Nitrated Fatty Acids, Novel Anti-inflammatory Mediator in Allergic Airway Disease
    Raju C Reddy; Fiscal Year: 2013
    ..abstract_text> ..
  10. TSLP and the Pathophysiology of Asthma
    Steven F Ziegler; Fiscal Year: 2013
    ..The information gained from these studies will be critical in determining the role of TSLP in allergic lung disease, and will provide insight into whether TSLP is a therapeutic target for their treatment. ..
  11. The Role of C-C Chemokines in Eosinophil Airway Inflammation
    Nicholas W Lukacs; Fiscal Year: 2012
    ..These mechanisms may be similar to those that are involved in infants, where RSV-infected children often progress into having longterm pulmonary problems and in asthmatics for exacerbated disease. ..
  12. Lunatic fringe in peripheral T cells alters Notch-mediated Th2 pathology in viral
    Sumanta Mukherjee; Fiscal Year: 2013
    ..Thus our final aim - iii) is to address the regulation of Th2 cytokines by notch receptors in the context of LFNG during viral exacerbation of existing allergic disease. ..
  13. Allergen-induced IL-33 release by the airway epithelium
    SCOTT M O'GRADY; Fiscal Year: 2013
    ....
  14. Characterization of Floor Level Aerosol (PM) Exposure and Childhood Asthma
    Stuart Shalat; Fiscal Year: 2009
    ..The results of the laboratory analysis for endotoxins, molds and allergens for cockroaches (Bla g Yz), dust mites (Der f 1/p 1), dog (Can f 1), cat (Pel d 1) and mouse (Mus ml) will be evaluated for ..
  15. High Throughput Immunoassay for Flagellin
    Eva King; Fiscal Year: 2013
    ..The research could generate several product lines that are complementary to the company's current products and which will enable the company to expand its product range in new markets. ..
  16. Role of the DSC1 family of cation channels in insect neurophysiology and neurotox
    Chun Fang Wu; Fiscal Year: 2012
    ..Results could provide a basis for future development of a new generation of insecticides or new methods to enhance the efficacy of currently used insecticides, attractants, or repellents. ..
  17. Identification of Candidate Genes for Specific Immune Responsiveness to Cockroach
    Peisong Gao; Fiscal Year: 2011
    ..This will generate a reliable list of candidate genes for future studies in populations of African descent. ..
  18. Engrailed and the Control of Synaptic Circuitry in Drosophila
    Jonathan M Blagburn; Fiscal Year: 2010
    ..These molecules may be of great potential importance in neurological diseases such as Parkinson's or autism. ..
  19. Backyard Brains: Bringing Neurophysiology Into Secondary Schools
    Timothy Charles Marzullo; Fiscal Year: 2012
    ..and can detect and record the spiking activity (action potentials) of invertebrates such as crickets and cockroaches. We now aim: 1...
  20. Backyard Brains: Bringing Neurophysiology Into Secondary Schools
    GREGORY JOHN GAGE; Fiscal Year: 2013
    ..and can detect and record the spiking activity (action potentials) of invertebrates such as crickets and cockroaches;and the 2) "RoboRoach": a wireless neural stimulator for investigating insect behavior...
  21. Development of a Dissolving Film for Allergen Immunotherapy in Children
    Corinne Keet; Fiscal Year: 2013
    ..This methods developed here have to the potential to address the fundamental problems that currently limit or entirely prevent translation of immunotherapy in children from research settings to the clinic. ..
  22. Quercetin Treatment of Airway Inflammation
    MARC HERSHENSON; Fiscal Year: 2006
    ..This project examines the value of quercetin, a plant pigment, in preventing airway inflammation in mouse models of disease. This work may lead to new treatments for asthma, cystic fibrosis or chronic bronchitis. ..
  23. INSECT DIURETIC HORMONSES: STRUCTURES AND FUNCTION
    DAVID SCHOOLEY; Fiscal Year: 2003
    ..The ligand binding site on the identified receptor will be approached by protein cross-linking and molecular biological approaches. ..
  24. Health Effects of CREON2000 In Asthmatic Children
    Mark Glazman; Fiscal Year: 2003
    ....
  25. Socio-Cultural Influences on Allergic Sensitization
    Ginger Chew; Fiscal Year: 2006
    ..We must understand how the two lead to allergic sensitization and be cognizant that they both will be required for the most effective primary prevention of allergic asthma. ..
  26. IMMUNOCHEMICAL ASSAY OF AEROALLERGENS
    Charles Reed; Fiscal Year: 1991
    ....
  27. A STRATEGY FOR SPREADING GENES IN CHAGAS DISEASE VECTORS
    Ravi Durvasula; Fiscal Year: 2004
    ..cruzi (ants, crickets, fleas and cockroaches) but-may be exposed to CRUZIGARD will be determined...
  28. Rapid Test for Monitoring Dust Mite Avoidance in Homes
    Martin Chapman; Fiscal Year: 2004
    Allergens found in the home derived from dust mites, animal dander, cockroaches and fungi are commonly associated with the development of asthma...
  29. Asthma and Lead Prevention in Chicago Public Housing
    Rachel Rosenberg; Fiscal Year: 2004
    ....
  30. DUST MITE, COCKROACH AND CAT ALLERGENS IN ASTHMA
    Thomas Platts Mills; Fiscal Year: 2001
    ..immunoassays for allergens derived from dust mites of the genus Dermatophagoides, the cat Felis domesticus and cockroaches, eg. Blatella germanica...
  31. COCKROACH ALLERGENS--IMMUNOCHEMISTRY & ALLERGIC DISEASE
    Martin Chapman; Fiscal Year: 2000
    b>Cockroaches (CR) infesting houses produce protein allergens which are an important cause of IgE mediated allergic reactions and asthma among minority populations living in sub-standard housing...
  32. DIET, IMMUNE MODULATION, AND ASTHMA IN EARLY LIFE
    Scott Weiss; Fiscal Year: 2002
    ....
  33. Risk Factors Accounting for Neighborhood Differences in Asthma Prevalence
    Matthew S Perzanowski; Fiscal Year: 2010
    ..Aim 3. We hypothesize that among children sensitized to at least one allergen (i.e., atopic), those who live in a HAPN will be more likely to have asthma than those who live in an LAPN. ..
  34. COMMUNITY PREVENTION INTERVENTIONS FOR URBAN DEMOLITION
    Mark Farfel; Fiscal Year: 2002
    ..is likely to contain multiple environmental hazards, including lead-containing paint and dust, asbestos, rats, cockroaches, allergens and molds...
  35. REGULATION OF INSECT JUVENILE HORMONE BIOSYNTHESIS
    LINDA RESTIFO; Fiscal Year: 2001
    ..The study of CYP4C7 is a first and unique opportunity to study the processes by which the corpora allata are turned off. These processes have until now been addressed mostly at the morphological level. ..
  36. Rodent Allergen in Homes of Latino Children with Asthma
    Jill Berg; Fiscal Year: 2004
    ..Indoor environmental allergens such as cockroaches, dust mites, mold, pet dander, tobacco smoke and other agents can be effectively controlled and have been ..
  37. TEAM TARGETING THE ENVIRONMENT AND ASTHMA MANAGEMENT
    Ellen Crain; Fiscal Year: 2000
    ..It is hypothesized that functional morbidity and utilization will be significantly less for children in the TEAM intervention group compared with the control group. ..
  38. RECEPTORS AS TARGETS FOR INSECTICIDES
    AMIRA ELDEFRAWI; Fiscal Year: 1991
    ..The emphasis will be on utilization of our biochemical data and others' electrophysiological data to compare neurotransmitter receptors of insects with those of mammals...
  39. CHICAGO INNER CITY ASTHMA STUDY
    Richard Evans; Fiscal Year: 2001
    ..The CICAS believes that its study design permits the determination of the most effective intervention that is also cost-effective. ..
  40. EPIDEMIOLOGY OF AIRWAYS RESPONSIVENESS
    Scott Weiss; Fiscal Year: 2000
    ....
  41. Peer Education in Pregnancy Study
    Victoria Persky; Fiscal Year: 2006
    ..Results of this study will assist in elucidating the etiologic pathway by which asthma develops early in life, as well as assist in the development of effective intervention programs. ..
  42. AIRWAY DISEASE AND COCKROACH EXPOSURE IN PUBLIC HOUSING
    Alkis Togias; Fiscal Year: 2003
    ..Recently, we and others have suggested that allergic sensitization to cockroaches constitutes an important predictor of asthma morbidity in low income patients...
  43. Determinants of Asthma Morbidity in an Urban Population
    Juan Wisnivesky; Fiscal Year: 2006
    ..During the five-year project, the candidate will pursue advanced graduate work in clinical epidemiology and health services research to further develop his scientific skills. ..
  44. COMPLEXITY OF IN VIVO AXON GUIDANCE
    MICHAEL DAILEY; Fiscal Year: 2002
    ..The information obtained from studies of this insect are likely to be very relevant to understanding these processes in mammals. ..
  45. COMMUNITY BASED ASTHMA INTERVENTION IN PREGNANT WOMEN
    Victoria Persky; Fiscal Year: 2000
    ..affect the development and course of asthma, including exposure to in utero and passive smoke, pets, molds, cockroaches, and dust mites...
  46. ORIGINS OF INDUCIBLE HUMORAL IMMUNITY
    Richard Karp; Fiscal Year: 1993
    ..The results from these investigations should provide valuable information not only regarding the definitions of invertebrate immunity, but also for our understanding of the evolution of immune reactivity in general...
  47. NEUROHORMONAL REGULATION OF CYTOCHROME SYNTHESIS
    LARRY KEELEY; Fiscal Year: 1980
    ..of cytochromes aa3 plus b is neurohormonally regulated in fat body mitochondria of Blaberus discoidalis cockroaches and occurs during fat body maturation in recently-emerged adults...
  48. Endotoxin, Obesity, and Asthma in NYC Head Start
    Judith Jacobson; Fiscal Year: 2005
    ..We will also conduct environmental sampling within the Head Start centers twice a year. Our goal is to identify risk factors that interventions can target to lighten the burden of asthma on school-age children. ..
  49. COCKROACH ALLERGEN CONTROL TECHNIQUES
    Larry Williams; Fiscal Year: 2002
    ..The study will provide the subjects with the materials needed to eradicate cockroaches and to clean the dwelling as in the first group...
  50. MOTOR PATTERNS IN CROSS REGENERATED NERVES
    CHARLES FOURTNER; Fiscal Year: 1980
    ..Cross-innervated legs can be de-efferented leaving an afferent limb. The specific aim is to study the role specific sense organs may play in walking...
  51. GENERATION OF NEURONAL FORM AND FUNCTION
    JEFFREY DENBURG; Fiscal Year: 1992
    ..The development of neuronal control of the endocrine system in cockroaches and identification of the neuropeptides involved will produce information useful in regulating excessive ..
  52. Genetic Studies of Immune Responsiveness to Cockroach
    Kathleen Barnes; Fiscal Year: 2007
    ..We will also examine the interactive effect of current cockroach allergen exposure and susceptibility loci associated with asthma severity. ..
  53. Howard/Hopkins Center for Reducing Asthma Disparities
    Georgia Dunston; Fiscal Year: 2006
    ..g. cockroaches, dust), differences in the accessibility and quality of asthma medical care for patients of differing ..
  54. REDUCING INDOOR ALLERGEN EXPOSURES IN NORTHERN MANHATTAN
    Patrick Kinney; Fiscal Year: 2000
    ..5. Develop and implement culturally appropriate methods and materials for communicating the study findings to the community involved. ..
  55. SOCIAL FACTORS & THE ENVIRONMENT IN PEDIATRIC ASTHMA
    Carolyn Berry; Fiscal Year: 2004
    ..All stages of the project include a Community Outreach and Education Plan, culminating in community meetings in the final year to share results and consider next steps. ..
  56. Role of cockroach proteases in airway inflammation
    Kristen Page; Fiscal Year: 2009
    ..Finally, we will investigate the role of endogenous TNF alpha in the airways using a TNF alpha neutralizing antibody and TNF alpha knockout mice. ..
  57. Neurobiology of a Simple Oculomotor System: Circuitry
    NICHOLAS STRAUSFELD; Fiscal Year: 2008
    ..It will also lead to the implementation of silicon-based circuits that enable motion detection and shape discrimination and potentially provide the basis for a visual prosthetic device. [unreadable] [unreadable]..
  58. Conf Proposal:Gordon Research Conf on Neuroethology 2005
    NICHOLAS STRAUSFELD; Fiscal Year: 2005
    ..The conference is intended for the broad neuroethological community at all professional levels including advanced graduate and postdoctoral trainees. ..
  59. UVA Asthma and Allergic Diseases Center
    Thomas Platts Mills; Fiscal Year: 2005
    ..Understanding the mechanisms involved is essential for defining new approaches to treatment and prevention and also for explaining the increasing prevalence of asthma. ..
  60. INNER CITY COCKROACH ALLERGEN REDUCTION TRIAL
    Peyton Eggleston; Fiscal Year: 2002
    ..years with moderately severe asthma, a positive skin test to cockroach, live in a home that is infested with cockroaches and have elevated Bla g 1...
  61. HOME BASED ENVIRONMENTAL ADHERENCE TRIAL
    Peyton Eggleston; Fiscal Year: 2002
    ....
  62. Epidemiology of asthma: risk and prognosis in a cohort from birth to adolescence
    Syed Hasan Arshad; Fiscal Year: 2010
    ..Our work brings together a multidisciplinary research team with a proven record of collaboration and expertise in respiratory medicine, allergy and immunology, epidemiology, genetics, and biostatistics. ..
  63. Prevention of chronic asthma: age 7 follow up
    MARY KLINNERT; Fiscal Year: 2005
    ..In addition, we will use the early data to identify developmental precursors for poor adherence and increased asthma morbidity at age 7. ..
  64. Severe Asthma From Respiratory Infections
    William W Busse; Fiscal Year: 2010
    ..These studies will provide new insights into the mechanisms of asthma, particularly severe disease, and possibilities of new approaches to treatment. ..
  65. REGULATION OF JUVENILE HORMONE SYNTHESIS
    Barbara Stay; Fiscal Year: 2003
    ....