polychaeta

Summary

Summary: A class of marine annelids including sandworms, tube worms, clamworms, and fire worms. It includes also the genus Myxicola infundibulum.

Top Publications

  1. ncbi Profiling by image registration reveals common origin of annelid mushroom bodies and vertebrate pallium
    Raju Tomer
    Developmental Biology Unit, European Molecular Biology Laboratory, D 69117 Heidelberg, Germany
    Cell 142:800-9. 2010
  2. ncbi Ciliary photoreceptors with a vertebrate-type opsin in an invertebrate brain
    Detlev Arendt
    Developmental Biology Department, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69012 Heidelberg, Germany
    Science 306:869-71. 2004
  3. ncbi Comparative phylogeography among hydrothermal vent species along the East Pacific Rise reveals vicariant processes and population expansion in the South
    S Plouviez
    Laboratoire Adaptation et Diversité en Milieu Marin, Universite Pierre et Marie Curie Paris 6, Paris, France
    Mol Ecol 18:3903-17. 2009
  4. pmc CO(2)-driven ocean acidification alters and weakens integrity of the calcareous tubes produced by the serpulid tubeworm, Hydroides elegans
    Vera Bin San Chan
    The Swire Institute of Marine Science and School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People s Republic of China
    PLoS ONE 7:e42718. 2012
  5. ncbi Dynamics of cell proliferation and apoptosis reflect different life strategies in hydrothermal vent and cold seep vestimentiferan tubeworms
    Bettina Pflugfelder
    Department Marine Biology, Faculty of Life Sciences, University of Vienna, Althanstrasse 14, A 1090, Vienna, Austria
    Cell Tissue Res 337:149-65. 2009
  6. ncbi Immunofluorescence analysis of the internal brain anatomy of Nereis diversicolor (Polychaeta, Annelida)
    C M Heuer
    Department of Developmental Biology and Morphology of Animals, Institute for Biology II, RWTH Aachen, Aachen, Germany
    Cell Tissue Res 331:713-24. 2008
  7. ncbi Physiological proteomics of the uncultured endosymbiont of Riftia pachyptila
    Stephanie Markert
    Institute of Marine Biotechnology, Walther Rathenau Strasse 49, D 17489 Greifswald, Germany
    Science 315:247-50. 2007
  8. pmc Proteome adaptation to high temperatures in the ectothermic hydrothermal vent Pompeii worm
    Didier Jollivet
    Adaptation and Diversité en Milieu Marin, CNRS UMR 7144, Roscoff, France
    PLoS ONE 7:e31150. 2012
  9. ncbi Insights into the composition, morphology, and formation of the calcareous shell of the serpulid Hydroides dianthus
    Adrienne E Tanur
    Department of Chemistry, University of Toronto, 80 St George St, Toronto, ON, Canada M5S 3H6
    J Struct Biol 169:145-60. 2010
  10. ncbi Restriction to large-scale gene flow vs. regional panmixia among cold seep Escarpia spp. (Polychaeta, Siboglinidae)
    Dominique A Cowart
    Department of Biology, The Pennsylvania State University, 208 Erwin W Mueller Laboratory, University Park, PA 16802, USA
    Mol Ecol 22:4147-62. 2013

Detail Information

Publications283 found, 100 shown here

  1. ncbi Profiling by image registration reveals common origin of annelid mushroom bodies and vertebrate pallium
    Raju Tomer
    Developmental Biology Unit, European Molecular Biology Laboratory, D 69117 Heidelberg, Germany
    Cell 142:800-9. 2010
    ..These data indicate deep homology of pallium and mushroom bodies and date back the origin of higher brain centers to prebilaterian times...
  2. ncbi Ciliary photoreceptors with a vertebrate-type opsin in an invertebrate brain
    Detlev Arendt
    Developmental Biology Department, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69012 Heidelberg, Germany
    Science 306:869-71. 2004
    ..Comparative analysis indicates that both types of photoreceptors, with distinct opsins, coexisted in Urbilateria, the last common ancestor of insects and vertebrates, and sheds new light on vertebrate eye evolution...
  3. ncbi Comparative phylogeography among hydrothermal vent species along the East Pacific Rise reveals vicariant processes and population expansion in the South
    S Plouviez
    Laboratoire Adaptation et Diversité en Milieu Marin, Universite Pierre et Marie Curie Paris 6, Paris, France
    Mol Ecol 18:3903-17. 2009
    ....
  4. pmc CO(2)-driven ocean acidification alters and weakens integrity of the calcareous tubes produced by the serpulid tubeworm, Hydroides elegans
    Vera Bin San Chan
    The Swire Institute of Marine Science and School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People s Republic of China
    PLoS ONE 7:e42718. 2012
    ....
  5. ncbi Dynamics of cell proliferation and apoptosis reflect different life strategies in hydrothermal vent and cold seep vestimentiferan tubeworms
    Bettina Pflugfelder
    Department Marine Biology, Faculty of Life Sciences, University of Vienna, Althanstrasse 14, A 1090, Vienna, Austria
    Cell Tissue Res 337:149-65. 2009
    ....
  6. ncbi Immunofluorescence analysis of the internal brain anatomy of Nereis diversicolor (Polychaeta, Annelida)
    C M Heuer
    Department of Developmental Biology and Morphology of Animals, Institute for Biology II, RWTH Aachen, Aachen, Germany
    Cell Tissue Res 331:713-24. 2008
    ..we provide a survey of the internal neuroarchitecture of the brain of the aciculate ragworm Nereis diversicolor (Polychaeta, Annelida)...
  7. ncbi Physiological proteomics of the uncultured endosymbiont of Riftia pachyptila
    Stephanie Markert
    Institute of Marine Biotechnology, Walther Rathenau Strasse 49, D 17489 Greifswald, Germany
    Science 315:247-50. 2007
    ..Unexpectedly, the symbiont uses the reductive tricarboxylic acid cycle in addition to the previously identified Calvin cycle for CO2 fixation...
  8. pmc Proteome adaptation to high temperatures in the ectothermic hydrothermal vent Pompeii worm
    Didier Jollivet
    Adaptation and Diversité en Milieu Marin, CNRS UMR 7144, Roscoff, France
    PLoS ONE 7:e31150. 2012
    ....
  9. ncbi Insights into the composition, morphology, and formation of the calcareous shell of the serpulid Hydroides dianthus
    Adrienne E Tanur
    Department of Chemistry, University of Toronto, 80 St George St, Toronto, ON, Canada M5S 3H6
    J Struct Biol 169:145-60. 2010
    ..The SOM and organic tube lining were found to contain carboxylated and sulphated polysaccharides. In an artificial seawater solution, the SOM and the organic tube lining mediated CaCO(3) mineralization in vitro...
  10. ncbi Restriction to large-scale gene flow vs. regional panmixia among cold seep Escarpia spp. (Polychaeta, Siboglinidae)
    Dominique A Cowart
    Department of Biology, The Pennsylvania State University, 208 Erwin W Mueller Laboratory, University Park, PA 16802, USA
    Mol Ecol 22:4147-62. 2013
    ..southwardae (n = 80), no population structure was detected. These findings suggest that despite the patchiness and isolation of seep habitats, connectivity is high on regional scales. ..
  11. pmc Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis
    David S Shin
    Department of Molecular Biology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
    J Mol Biol 385:1534-55. 2009
    ..pompejana provides macromolecules highly similar to those from humans, but with enhanced stability more suitable for scientific and medical applications...
  12. ncbi Phylogeography of the common ragworm Hediste diversicolor (Polychaeta: Nereididae) reveals cryptic diversity and multiple colonization events across its distribution
    M Virgilio
    Royal Belgian Institute of Natural Sciences, Brussels, Belgium
    Mol Ecol 18:1980-94. 2009
    Previous studies on the common ragworm Hediste diversicolor (Polychaeta: Nereididae) revealed a marked genetic fragmentation across its distribution and the occurrence of sibling taxa in the Baltic Sea...
  13. ncbi Genetic drift and collective dispersal can result in chaotic genetic patchiness
    Thomas Broquet
    CNRS, UMR 7144, Team Div and Co, Lab Adaptation et Diversité en Milieu Marin, Station Biologique de Roscoff, Roscoff, France
    Evolution 67:1660-75. 2013
    ..These results call for empirical studies of the effective number of breeders producing larval cohorts, and population genetics at the larval stage...
  14. ncbi Amino acid sequence of the small cadmium-binding protein (MP II) from Nereis diversicolor (annelida, polychaeta). Evidence for a myohemerythrin structure
    S Demuynck
    ERS 20 CNRS Phylogénie moléculaire des Annélides, Universite des Sciences et Technologies de Lille, Villeneuve d Ascq, France
    Eur J Biochem 217:151-6. 1993
    ....
  15. ncbi Early steps in microbial colonization processes at deep-sea hydrothermal vents
    Karine Alain
    Laboratoire de Microbiologie et de Biotechnologie des Extrêmophiles, Département de Valorisation des Produits, IFREMER, Centre de Brest, BP 70, 29280 Plouzane, France
    Environ Microbiol 6:227-41. 2004
    ....
  16. ncbi Transcriptome and quantitative proteome analysis reveals molecular processes associated with larval metamorphosis in the polychaete Pseudopolydora vexillosa
    Kondethimmahalli H Chandramouli
    KAUST Global Collaborative Research, Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong
    J Proteome Res 12:1344-58. 2013
    ..Further, transcriptomic and proteomic insights provide a new direction to understand the fundamental mechanisms that regulate larval metamorphosis in polychaetes...
  17. pmc Not whale-fall specialists, Osedax worms also consume fishbones
    Greg W Rouse
    Scripps Institution of Oceanography, UCSD 9500 Gilman Drive, La Jolla, CA 92093 0202, USA
    Biol Lett 7:736-9. 2011
    ....
  18. ncbi Osedax: bone-eating marine worms with dwarf males
    G W Rouse
    South Australian Museum, North Terrace, Adelaide SA 5000, Australia
    Science 305:668-71. 2004
    ..DNA sequences reveal that the two Osedax species diverged about 42 million years ago and currently maintain large populations ranging from 10(5) to 10(6) adult females...
  19. ncbi High symbiont diversity in the bone-eating worm Osedax mucofloris from shallow whale-falls in the North Atlantic
    Caroline Verna
    Max Planck Institute for Marine Microbiology, Celsiusstr 1, 28359 Bremen, Germany
    Environ Microbiol 12:2355-70. 2010
    ..The observed diversity and distribution patterns indicate that the endosymbionts are transmitted horizontally from the environment with repeated infection events occurring as the host root tissues grow into the whale bones...
  20. ncbi The Osedax trophosome: organization and ultrastructure
    Sigrid Katz
    Department of Marine Biology, Faculty of Life Sciences, University of Vienna, Austria
    Biol Bull 220:128-39. 2011
    ..Comparison of all siboglinid trophosomes and re-evaluation of their body regions allows us to discuss whether the trophosomes are homologous and to hypothesize about the organization of the last common ancestor of Siboglinidae...
  21. pmc Stable transgenesis in the marine annelid Platynereis dumerilii sheds new light on photoreceptor evolution
    Benjamin Backfisch
    Max F Perutz Laboratories, Department of Microbiology, Immunobiology, and Genetics, University of Vienna, A 1030 Vienna, Austria
    Proc Natl Acad Sci U S A 110:193-8. 2013
    ..Our study marks significant advance for the understanding of photoreceptor cell (PRC) evolution and development and for Platynereis as a functional lophotrochozoan model system...
  22. pmc Fate of nitrate acquired by the tubeworm Riftia pachyptila
    P R Girguis
    Marine Science Institute, University of California at Santa Barbara, Santa Barbara, California 93106, USA
    Appl Environ Microbiol 66:2783-90. 2000
    ....
  23. ncbi 2D gel-based multiplexed proteomic analysis during larval development and metamorphosis of the biofouling polychaete tubeworm Hydroides elegans
    Yu Zhang
    KAUST Global Collaborative Research Program, Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong SAR, China
    J Proteome Res 9:4851-60. 2010
    ..Overall, our results indicated that the level of protein phosphorylation might play a crucial role in the initiation of larval settlement and metamorphosis...
  24. pmc Determining gene flow and the influence of selection across the equatorial barrier of the East Pacific Rise in the tube-dwelling polychaete Alvinella pompejana
    Sophie Plouviez
    Universite Pierre et Marie Curie Paris 6, Laboratoire Adaptation et Diversité en Milieu Marin, Roscoff, France
    BMC Evol Biol 10:220. 2010
    ..The present study evaluates the strength of the equatorial barrier to gene flow and tests for potential secondary contact zones between A. pompejana populations by comparing the mtCOI gene with nuclear genes...
  25. ncbi The polychaete Platynereis dumerilii (Annelida): a laboratory animal with spiralian cleavage, lifelong segment proliferation and a mixed benthic/pelagic life cycle
    Albrecht Fischer
    Institute of Zoology, University of Mainz, Germany
    Bioessays 26:314-25. 2004
    ..Platynereis can also become a stepping stone in the comparison of segmentation between annelids and arthropods because it comes closer to the putative ancestral morphology and style of development than other model annelids...
  26. ncbi Distinct patterns of genetic differentiation among annelids of eastern Pacific hydrothermal vents
    L A Hurtado
    Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, CA 95039, USA
    Mol Ecol 13:2603-15. 2004
    ..The present findings are compared with similar evidence from codistributed species of annelids, molluscs and crustaceans to identify potential dispersal filters in these eastern Pacific ridge systems...
  27. pmc Genetic diversity and potential function of microbial symbionts associated with newly discovered species of Osedax polychaete worms
    Shana K Goffredi
    California Institute of Technology, Pasadena, California 91125, USA
    Appl Environ Microbiol 73:2314-23. 2007
    ..Members of this unusual genus of bone-eating worms may form variable associations with symbiotic bacteria that allow for the observed differences in colonization and success in whale fall environments throughout the world's oceans...
  28. ncbi Metabolic versatility of the Riftia pachyptila endosymbiont revealed through metagenomics
    Julie C Robidart
    Scripps Institution of Oceanography, San Diego, CA, USA
    Environ Microbiol 10:727-37. 2008
    ..The physiology of Candidatus Endoriftia persephone is explored with respect to functionality while associated with a eukaryotic host, versus free-living in the hydrothermal environment...
  29. ncbi A new species of Osedax (Annelida: Siboglinidae) associated with whale carcasses off Kyushu, Japan
    Katsunori Fujikura
    Marine Biology and Ecology Research Program, Japan Agency for Marine Earth Science and Technology, Yokosuka, Kanagawa, Japan
    Zoolog Sci 23:733-40. 2006
    ..mucofloris. Osedax japonicus is easily distinguished from the other three known species by oviduct morphology, body length, and palp coloration in females. No males of O. japonicus have yet been found...
  30. ncbi Endosymbionts of Siboglinum fiordicum and the phylogeny of bacterial endosymbionts in Siboglinidae (Annelida)
    Daniel J Thornhill
    Department of Biological Sciences, 101 Rouse Life Sciences Building, Auburn University, Auburn, Alabama 36849, USA
    Biol Bull 214:135-44. 2008
    ..fiordicum, from Norway, are most closely related to symbionts of the frenulate Oligobrachia mashikoi from Japan, suggesting that symbionts of frenulates may share common evolutionary history or metabolic features...
  31. ncbi The metabolic demands of endosymbiotic chemoautotrophic metabolism on host physiological capacities
    J J Childress
    Department of Ecology, Evolution and Marine Biology, University of California, Santa Barbara, CA 93106, USA
    J Exp Biol 214:312-25. 2011
    ..These analyses suggest that the high demand for oxygen by chemoautotrophic and methanotrophic symbionts is likely a major factor precluding their endosymbiosis with cnidarians...
  32. ncbi Characterization of lipovitellin in eggs of the polychaete Neanthes arenaceodentata
    Richard F Lee
    Department of Marine Biochemistry, Skidaway Institute of Oceanography, 10 Ocean Science Circle, Savannah, GA 31411, USA
    Comp Biochem Physiol B Biochem Mol Biol 140:381-6. 2005
    ..The presence of muscle fragments and oil droplets in eleocytes suggests that eleocytes play an important role in providing the protein and lipid needed for the assembly of lipovitellin in the oocytes...
  33. ncbi Trochophora larvae: cell-lineages, ciliary bands, and body regions. 1. Annelida and Mollusca
    Claus Nielsen
    Zoological Museum University of Copenhagen, Universitetsparken 15, DK 2100 Copenhagen, Denmark
    J Exp Zool B Mol Dev Evol 302:35-68. 2004
    ..This supports the notion that the molluscs are not segmented like the annelids, and that the repeated structures seen in polyplacophorans and monoplacophorans do not represent a segmentation homologous to that of the annelids...
  34. ncbi Extending the generality of ecological models to artificial floating habitats
    Victoria J Cole
    Centre for Research on Ecological Impacts of Coastal Cities, Marine Ecology Laboratories A11, University of Sydney, NSW 2006, Australia
    Mar Environ Res 60:195-210. 2005
    ..Most importantly, processes that accounted for patterns of distribution of mobile and sessile organisms on artificial floating structures were similar to those repeatedly shown to create such patterns on natural rocky shores...
  35. ncbi Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in bilateria
    Alexandru S Denes
    Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, 69117, Germany
    Cell 129:277-88. 2007
    ..Our data indicate that this mediolateral architecture was present in the last common bilaterian ancestor and thus support a common origin of nervous system centralization in Bilateria...
  36. ncbi The unique adaptation of the life cycle of the coelomic gregarine Diplauxis hatti to its host Perinereis cultrifera (Annelida, Polychaeta): an experimental and ultrastructural study
    Gerard Prensier
    Laboratoire de Biologie Cellulaire et de Microscopie Electronique, UFR Medecine, 10 Bd Tonnellé, 37032 Tours Cedex 1, France
    J Eukaryot Microbiol 55:541-53. 2008
    ..Zygotes differentiate sporoblasts with eight sporozoites. The sporozoites exhibit the canonical structure of Apicomplexa, a polarized cell with micronemes and rhoptries...
  37. ncbi Capitella sp. I homeobrain-like, the first lophotrochozoan member of a novel paired-like homeobox gene family
    Andreas C Fröbius
    Kewalo Marine Lab, Pacific Bioscience Research Center, University of Hawaii, Honolulu, HI 96813, USA
    Gene Expr Patterns 6:985-91. 2006
    ..CapI-hbnl represents an important neural marker for characterization of the annelid nervous system...
  38. ncbi A postexposure feeding assay using the marine polychaete Neanthes arenaceodentata suitable for laboratory and in situ exposures
    Gunther Rosen
    Space and Naval Warfare Systems Center Pacific, San Diego, California, USA
    Environ Toxicol Chem 30:730-7. 2011
    ..The utility of this assay in actual marine and estuarine sediments is being assessed in situ at several North American sediment sites, and will be reported in future publications...
  39. ncbi Characterization and expression of calmodulin gene during larval settlement and metamorphosis of the polychaete Hydroides elegans
    Zhang Fan Chen
    KAUST Global Collaborative Research Program, Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China
    Comp Biochem Physiol B Biochem Mol Biol 162:113-9. 2012
    ..In conclusion, our results revealed that CaM has important functions in the larval settlement and metamorphosis of H. elegans...
  40. pmc Linking hydrothermal geochemistry to organismal physiology: physiological versatility in Riftia pachyptila from sedimented and basalt-hosted vents
    Julie C Robidart
    University of California Santa Cruz, Department of Ocean Sciences, Santa Cruz, California, United States of America
    PLoS ONE 6:e21692. 2011
    ..These observations raise new hypotheses regarding adaptations to the geochemical diversity of habitats occupied by Riftia, and the degree to which the environment influences symbiont physiology and evolution...
  41. ncbi Proteomic comparison of two invasive polychaete species and their naturally occurring F1-hybrids
    Miriam Blank
    Biozentrum Grindel und Zoologisches Museum, Universitat Hamburg, Martin Luther King Platz 3, 20146 Hamburg, Germany
    J Proteome Res 11:897-905. 2012
    ..It furthermore indicates the feasibility of proteomic methods for analyses of speciation in Marenzelleria siblings as well as of hybridization events in secondary contact zones in general...
  42. pmc Exploring the limit of metazoan thermal tolerance via comparative proteomics: thermally induced changes in protein abundance by two hydrothermal vent polychaetes
    Geoffrey F Dilly
    Department of Organismic and Evolutionary Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Proc Biol Sci 279:3347-56. 2012
    ..Ultimately, oxidative stress may be the key factor in limiting all metazoan thermotolerance...
  43. pmc Gel-based and gel-free identification of proteins and phosphopeptides during egg-to-larva transition in polychaete Neanthes arenaceodentata
    Kondethimmanahalli H Chandramouli
    Division of Life Science, Hong Kong University of Science and Technology, Hong Kong SAR, China
    PLoS ONE 7:e38814. 2012
    ....
  44. ncbi Organization and microanatomy of the Sclerolinum contortum trophosome (Polychaeta, Siboglinidae)
    Irmgard Eichinger
    Department of Marine Biology, University of Vienna, Austria
    Biol Bull 220:140-53. 2011
    ..Using Raman microspectroscopy we demonstrate that the endosymbionts of S. contortum from the Gulf of Mexico contain sulfur vesicles, and we argue for a chemoautotrophic sulfur-oxidizing metabolism...
  45. ncbi Microbial diversity in Frenulata (Siboglinidae, Polychaeta) species from mud volcanoes in the Gulf of Cadiz (NE Atlantic)
    Clara F Rodrigues
    CESAM and Departamento de Biologia, Universidade de Aveiro, Campus de Santiago, Portugal
    Antonie Van Leeuwenhoek 100:83-98. 2011
    ....
  46. ncbi SEM study of semi-oriented tube microstructures of Serpulidae (Polychaeta, Annelida): implications for the evolution of complex oriented microstructures
    Olev Vinn
    Department of Geology, Institute of Ecology and Earth Sciences, University of Tartu, Tartu, Estonia
    Microsc Res Tech 76:453-6. 2013
    ..The occurrence of semi-oriented microstructures in serpulids supports the hypothesis that complex oriented microstructures are derived from isotropic microstructures via evolution of a biochemical crystal orientation control mechanism...
  47. ncbi Bacteria associated with sabellids (Polychaeta: Annelida) as a novel source of surface active compounds
    Carmen Rizzo
    Department of Biological and Environmental Sciences DISBA, University of Messina, Viale F Stagno d Alcontres 31, 98166 Messina, Italy
    Mar Pollut Bull 70:125-33. 2013
    ..Our results suggest that filter-feeding Polychaetes could represent a novel and yet unexplored source of biosurfactant-producing bacteria...
  48. pmc Insights into metazoan evolution from Alvinella pompejana cDNAs
    Nicolas Gagniere
    Department of Structural Biology and Genomics, Institut de Genetique et de Biologie Moleculaire et Cellulaire, CERBM F 67400 Illkirch, France
    BMC Genomics 11:634. 2010
    ..It represents an outstanding model organism for studying adaptation to harsh physicochemical conditions and for isolating stable macromolecules resistant to high temperatures...
  49. pmc A remarkable diversity of bone-eating worms (Osedax; Siboglinidae; Annelida)
    Robert C Vrijenhoek
    Monterey Bay Aquarium Research Institute, Moss Landing, CA, USA
    BMC Biol 7:74. 2009
    ..To assess their phylogenetic relationships and possible status as new undescribed species, we examined DNA sequences from two mitochondrial (COI and 16S rRNA) and three nuclear genes (H3, 18S and 28S rRNA)...
  50. ncbi Detecting benthic community responses to pollution in estuaries: a field mesocosm approach
    Allyson L O'Brien
    Department of Zoology, Centre for Aquatic Pollution Identification and Management CAPIM, The University of Melbourne, Parkville, Victoria 3010, Australia
    Environ Pollut 175:45-55. 2013
    ..Consistent responses across estuaries suggest numbers of individuals, and especially Capitella sp., could be used to identify contaminated sediments in estuaries with similar fauna and site characteristics...
  51. ncbi Vasa unveils a common origin of germ cells and of somatic stem cells from the posterior growth zone in the polychaete Platynereis dumerilii
    N Rebscher
    Institute of Zoology, Philipps University Marburg, Karl von Frisch Strasse 8, 35032 Marburg, Germany
    Dev Biol 306:599-611. 2007
    ..Our data suggest a common origin of germ cells and of somatic stem cells, similar to the situation found in planarians and cnidarians, which may constitute the ancestral mode of germ cell specification in Metazoa...
  52. ncbi Comparative glycoproteome analysis: dynamics of protein glycosylation during metamorphic transition from Pelagic to Benthic life stages in three invertebrates
    Kondethimmanahalli H Chandramouli
    KAUST Global Collaborative Research Program, Division of Life Science, Hong Kong University of Science and Technology, Hong Kong SAR, China
    J Proteome Res 11:1330-40. 2012
    ..The current study provides preliminary information on protein glycosylation in marine invertebrates that will serve as a solid basis for future comprehensive analysis of glycobiology during larval settlement and metamorphosis...
  53. ncbi A new genus Gadimyxa with three new species (Myxozoa, Parvicapsulidae) parasitic in marine fish (Gadidae) and the two-host life cycle of Gadimyxa atlantica n. sp
    Marianne Køie
    Marine Biological Laboratory, University of Copenhagen, DK 3000 Helsingør, Denmark
    J Parasitol 93:1459-67. 2007
    ..This is the second known myxozoan 2-host life cycle in the marine environment. Phylogenetic analyses based on partial small subunit rDNA sequences places Gadimyxa spp. among Parvicapsula spp. in the Parvicapsulidae...
  54. ncbi Sulfur-oxidizing symbionts have not co-evolved with their hydrothermal vent tube worm hosts: an RFLP analysis
    B E Laue
    Section of Microbiology, University of California, Davis 95616, USA
    Mol Mar Biol Biotechnol 6:180-8. 1997
    ..This study strongly supports the conclusion that the symbionts are acquired de novo by each generation of juvenile tube worms from a common source in the surrounding sea water...
  55. ncbi Molecular phylogenetics of bacterial endosymbionts and their vestimentiferan hosts
    R A Feldman
    Center for Theoretical and Applied Genetics, Cook College, Rutgers University, New Brunswick, New Jersey, USA
    Mol Mar Biol Biotechnol 6:268-77. 1997
    ..A third endosymbiont type, related to the seep species, was found in a tube worm collected from a whale carcass. Our results are consistent with a horizontal model of symbiont transmission...
  56. ncbi Phylogeny of Aphroditiformia (Polychaeta) based on molecular and morphological data
    Helena Wiklund
    Department of Zoology, Goteborg University, PO Box 463, Göteborg SE 405 30, Sweden
    Mol Phylogenet Evol 37:494-502. 2005
    ..Palmyra is sister to Aphrodita, and both Pisione and Pholoe are positioned within Sigalionidae, suggesting that both family names Pisionidae and Pholoidae should be treated as junior synonyms of Sigalionidae...
  57. ncbi Progenesis in Eunicida ("Polychaeta," Annelida)--separate evolutionary events? Evidence from molecular data
    Torsten H Struck
    Spezielle Zoologie, Fachbereich Biologie, Universitat Osnabruck, Barbarastrasse 11, D 49069 Osnabruck, Germany
    Mol Phylogenet Evol 25:190-9. 2002
    ..psammophilus is rejected by several tests, substantiating the hypothesis of separate progenetic evolutionary events. Furthermore, the molecular data indicate polyphyly of the Dorvilleidae...
  58. ncbi Effects of salinity on spawning and early development of the tube-building polychaete Hydroides elegans in Hong Kong: not just the sperm's fault?
    Jan A Pechenik
    Biology Department, Tufts University, Medford, MA 02155, USA
    Biol Bull 212:151-60. 2007
    ..The results suggest that failure of early development at low salinity in this species in large part reflects an inability of newly fertilized eggs to complete meiosis and cleave, rather than simply a failure of fertilization...
  59. ncbi The ionic composition of the hydrothermal vent tube worm Riftia pachyptila: evidence for the elimination of SO2-4SO and H+ and for a Cl-/HCO-3HCO shift
    S K Goffredi
    Monterey Bay Aquarium Research Institute, P O Box 628, Moss Landing, CA 95039, USA
    Physiol Biochem Zool 72:296-306. 1999
    ....
  60. ncbi When gaps really are gaps: statistical phylogeography of hydrothermal vent invertebrates
    Asta Audzijonyte
    Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, California 95039, USA
    Evolution 64:2369-84. 2010
    ..The simulation approaches presented here might be useful for testing the significance of inferred phylogeographic gaps in other species...
  61. ncbi Spirorbid [correction of Spirorchid] and serpulid polychaetes are candidates as invertebrate hosts for myxozoa
    Marianne Køie
    Marine Biological Laboratory, University of Copenhagen, DK 3000 Helsingør, Denmark
    Folia Parasitol (Praha) 49:160-2. 2002
  62. ncbi Evolution of the sulfide-binding function within the globin multigenic family of the deep-sea hydrothermal vent tubeworm Riftia pachyptila
    Xavier Bailly
    Station Biologique de Roscoff, UPR 9042 CNRS UPMC INSU, Laboratoire Ecophysiologie, Roscoff, France
    Mol Biol Evol 19:1421-33. 2002
    ..A likely scenario on the evolution of this multigenic family is proposed and discussed from this data set...
  63. ncbi Three consecutive generations of nephridia occur during development of Platynereis dumerilii (Annelida, Polychaeta)
    Christian Hasse
    Morphology and Evolution of Animals, Philipps Universitat Marburg, Karl von Frisch Strasse 8, Marburg, Germany
    Dev Dyn 239:1967-76. 2010
    ..Development of three consecutive sets of nephridia with different morphology and biochemical properties was unexpected and reveals an interesting multistep process in the development of excretory structures in Platynereis...
  64. ncbi Effects of some cytoskeleton inhibitors on ooplasmic segregation in the Nereis virens egg
    A K Dondua
    Department of Embryology, St Petersburg State University, Russia
    Int J Dev Biol 41:853-8. 1997
    ..The inhibition of any of these elements delays or disturbs the ooplasmic segregation and simultaneous disruption of microtubules and microfilaments functions leads to total cessation of the process...
  65. ncbi Morphology, molecular data, and development of Zschokkella mugilis (Myxosporea, Bivalvulida) in a polychaete alternate host, Nereis diversicolor
    Luís F Rangel
    Universidade do Porto, Faculdade de Ciencias, Departamento de Zoologia Antropologia, Rua do Campo Alegre, s n Edifício FC4, 4169 007 Porto, Portugal
    J Parasitol 95:561-9. 2009
    ..Infection was detected only in the winter and spring. In the Aveiro estuary (Portugal), the overall prevalence of infection of the polychaete was 0.5%...
  66. ncbi Nitrogen metabolites and related enzymatic activities in the body fluids and tissues of the hydrothermal vent tubeworm Riftia pachyptila
    M De Cian
    Equipe Ecophysiologie, Observatoire Océanologique de Roscoff UPMC, CNRS, INSU, Station Biologique, BP 74, F 29682 Roscoff Cedex, France
    J Exp Biol 203:2907-20. 2000
    ..Although no definitive conclusions could be drawn regarding the nitrogen regime of Riftia pachyptila, this in vitro study gives several indications for future research in this area...
  67. ncbi Involvement of Manayunkia speciosa (Annelida: Polychaeta: Sabellidae) in the life cycle of Parvicapsula minibicornis, a myxozoan parasite of Pacific salmon
    Jerri L Bartholomew
    Center for Fish Disease Research, Department of Microbiology, Nash Hall 220, Oregon State University, Corvallis, Oregon 97331, USA
    J Parasitol 92:742-8. 2006
    ..This life cycle is 1 of only about 30 known from more than 1,350 myxozoan species, and only the second known from a freshwater polychaete...
  68. ncbi The marine herring myxozoan Ceratomyxa auerbachi (Myxozoa: Ceratomyxidae) uses Chone infundibuliformis (Annelida: Polychaeta: Sabellidae) as invertebrate host
    Marianne Køie
    Marine Biological Laboratory, University of Copenhagen, DK 3000 Helsingør, Denmark
    Folia Parasitol (Praha) 55:100-4. 2008
    ..that actinospores of the tetractinomyxon type, which develop in Chone infundibuliformis Krøyer (Annelida, Polychaeta, Sabellidae) from the northern Øresund, Denmark, are identical with Ceratomyxa auerbachi Kabata, 1962 (Myxozoa, ..
  69. ncbi Ellipsomyxa gobii (Myxozoa: Ceratomyxidae) in the common goby Pomatoschistus microps (Teleostei: Gobiidae) uses Nereis spp. (Annelida: Polychaeta) as invertebrate hosts
    Marianne Køie
    Marine Biological Laboratory, University of Copenhagen, DK 3000 Helsingør, Denmark
    Folia Parasitol (Praha) 51:14-8. 2004
    Nereis diversicolor O.F. Müller and N. succinea Frey et Leuckart (Polychaeta, Nereidae) living in brackish shallow areas in Denmark are naturally infected with tetractinomyxon actinospores. Infected Nereis spp...
  70. pmc Hedgehog signaling regulates segment formation in the annelid Platynereis
    Nicolas Dray
    Centre de Génétique Moléculaire du CNRS, FRE 3144, Avenue de la Terrasse, 91189 Gif sur Yvette, France
    Science 329:339-42. 2010
    ..The molecular similarity of segment patterning functions of the Hedgehog pathway in an annelid and in arthropods supports a common origin of segmentation in protostomes...
  71. ncbi Species effects on ecosystem processes are modified by faunal responses to habitat composition
    Mark T Bulling
    Environment Department, University of York, Heslington, York, YO10 5DD, UK
    Oecologia 158:511-20. 2008
    ....
  72. ncbi Evolutionary innovation: a bone-eating marine symbiosis
    Shana K Goffredi
    Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, CA 95039, USA
    Environ Microbiol 7:1369-78. 2005
    ..Stable isotopes and fatty acid analyses suggest that these unusual endosymbionts are likely responsible for the nutrition of this locally abundant and reproductively prolific deep-sea worm...
  73. pmc Metagenome analysis of an extreme microbial symbiosis reveals eurythermal adaptation and metabolic flexibility
    Joseph J Grzymski
    Division of Earth and Ecosystem Sciences, Desert Research Institute, 2215 Raggio Parkway, Reno, NV 89512, USA
    Proc Natl Acad Sci U S A 105:17516-21. 2008
    ..The success of Epsilonproteobacteria as episymbionts in hydrothermal vent ecosystems is a product of adaptive capabilities, broad metabolic capacity, strain variance, and virulent traits in common with pathogens...
  74. ncbi Chemical speciation drives hydrothermal vent ecology
    G W Luther
    College of Marine Studies, University of Delaware, Lewes, Delaware 19958, USA
    Nature 410:813-6. 2001
    ....
  75. ncbi Sharp genetic break between Atlantic and English Channel populations of the polychaete Pectinaria koreni, along the North coast of France
    M T Jolly
    Evolution et Génétique des Populations Marines, Station Biologique de Roscoff, CNRS UPMC, UMR 7127, B P 74, 29682, Roscoff, France
    Heredity (Edinb) 94:23-32. 2005
    ..features on the observed patterns of genetic structure in subdivided populations of Pectinaria koreni (Polychaeta: Pectinariidae) along the coasts of Brittany and the English Channel...
  76. ncbi Expression of 'segmentation' genes during larval and juvenile development in the polychaetes Capitella sp. I and H. elegans
    Elaine C Seaver
    Kewalo Marine Lab, PBRC University of Hawaii, Honolulu, 96813, USA
    Dev Biol 289:179-94. 2006
    ..elegans are not comparable to the highly conserved ectodermal segment polarity pattern observed in arthropods at any life history stage, consistent with distinct origins of segmentation between annelids and arthropods...
  77. ncbi Estuarine-scale genetic variation in the polychaete hobsonia Florida (ampharetidae; annelida) in long island sound and relationships to pleistocene glaciations
    Mary Ann Olson
    Department of Biology and Environmental Science, University of New Haven, 300 Boston Post Road, West Haven, Connecticut 06516, USA
    Biol Bull 217:86-94. 2009
    ..florida in LIS has been strongly influenced by a series of glacially mediated vicariance events, leading to periodic population isolation and mixing, further mediated by low dispersal and specialized habitat requirements...
  78. ncbi Genetic and morphometric characterization of mussels (Bivalvia: Mytilidae) from mid-atlantic hydrothermal vents
    P A Maas
    Center for Theoretical and Applied Genetics, Rutgers University, New Brunswick, New Jersey 08901, USA
    Biol Bull 196:265-72. 1999
    ..Nei's genetic distance (D) based on 14 allozyme loci was 0.112. A multivariate morphometric analysis yielded a canonical discriminant function that correctly identified individuals from these sites to species 95% of the time...
  79. ncbi Caudal and even-skipped in the annelid Platynereis dumerilii and the ancestry of posterior growth
    Renaud de Rosa
    Centre de Génétique Moléculaire du CNRS, Avenue de la Terrasse, 91198 Gif sur Yvette, France
    Evol Dev 7:574-87. 2005
    ..Together with the emerging results on the conservation of segmentation genes, these results reinforce the hypothesis that Urbilateria had a segmented trunk developing through posterior addition...
  80. ncbi Short-term responses to cadmium exposure in the estuarine polychaete Laeonereis acuta (polychaeta, Nereididae): subcellular distribution and oxidative stress generation
    Juliana Zomer Sandrini
    Departamento de Ciencias Fisiologicas, Fundacao Universidade Federal do Rio Grande, Brasil
    Environ Toxicol Chem 25:1337-44. 2006
    ..The effects caused by cadmium in the present study were observed only after 8 h of exposure, demonstrating that cadmium can generate oxidative stress...
  81. pmc Mitochondrial sequence data expose the putative cosmopolitan polychaete Scoloplos armiger (Annelida, Orbiniidae) as a species complex
    Christoph Bleidorn
    Animal Systematics and Evolution, Institute for Biology, Zoology, Free University Berlin, Koenigin Luise Str, 1 3, D 14195 Berlin, Germany
    BMC Evol Biol 6:47. 2006
    ..The aim of this study is to test the cosmopolitan status, as well as to clarify the systematics of this species complex in the Eastern North Atlantic, while using a few specimens from the Pacific Ocean for comparision...
  82. pmc Phosphoproteome analysis during larval development and metamorphosis in the spionid polychaete Pseudopolydora vexillosa
    Kondethimmanahalli H Chandramouli
    KAUST Global Collaborative Research Program, Division of Life Science, Hong Kong University of Science and Technology, Hong Kong SAR, China
    BMC Dev Biol 11:31. 2011
    ..A combination of affinity chromatography, 2D-PAGE, and mass spectrometry was used to identify the phosphoproteins in pre-competent larvae, competent larvae, and newly metamorphosed juveniles...
  83. pmc Sulfide binding is mediated by zinc ions discovered in the crystal structure of a hydrothermal vent tubeworm hemoglobin
    Jason F Flores
    Department of Biology, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 102:2713-8. 2005
    ..pachyptila hemoglobins by addition of a thiol inhibitor were also unsuccessful. These findings challenge the currently accepted paradigm of annelid hemoglobin evolution and adaptation to reducing environments...
  84. ncbi Integrative analysis of polychaete ontogeny: cell proliferation patterns and myogenesis in trochophore larvae of Sabellaria alveolata
    Nora Brinkmann
    Department of Biology, Research Group for Comparative Zoology, University of Copenhagen, Universitetsparken 15, Copenhagen Ø, Denmark
    Evol Dev 12:5-15. 2010
    ....
  85. ncbi The splicing factor U2AF65 is functionally conserved in the thermotolerant deep-sea worm Alvinella pompejana
    Kristy L Henscheid
    Department of Chemistry, Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403, USA
    Biochim Biophys Acta 1727:197-207. 2005
    ..We also determine that the general splicing mechanisms and signal sequences are conserved in the Pompeii worm, an annelid which has previously been uncharacterized in terms of splicing factors and signals...
  86. ncbi The benefits of polyandry in the free-spawning polychaete Galeolaria caespitosa
    D J Marshall
    School of Biological, Earth and Environmental Sciences, University of New South Wales, NSW, Australia
    J Evol Biol 18:735-41. 2005
    ..We suggest that these direct fertilization gains arising from polyandry will constitute an important source of selection on females to mate multiply in nature...
  87. ncbi Growth patterns during segmentation in the two polychaete annelids, Capitella sp. I and Hydroides elegans: comparisons at distinct life history stages
    Elaine C Seaver
    Kewalo Marine Laboratory, PBRC University of Hawaii, 41 Ahui St, Honolulu, HI 96813, USA
    Evol Dev 7:312-26. 2005
    ..The results of this study increase our understanding of the cellular origins of segments in annelids, and serve as a basis for interpretation of molecular expression patterns associated with segment formation in polychaetes...
  88. ncbi Neurogenesis in an annelid: characterization of brain neural precursors in the polychaete Capitella sp. I
    Néva P Meyer
    Kewalo Marine Laboratory, Pacific Biosciences Research Center, University of Hawaii, Honolulu, HI 96813, USA
    Dev Biol 335:237-52. 2009
    ..I brain neurogenesis displays several similarities with non-insect arthropod and vertebrate neurogenesis, providing a useful lophotrochozoan model for comparison...
  89. ncbi Clonal domains in postlarval Platynereis dumerilii (Annelida: Polychaeta)
    Christian Ackermann
    Zoologisches Institut der Johannes Gutenberg Universitaet, Mainz, Germany
    J Morphol 266:258-80. 2005
    ..A mesodermal envelope of the stomodeum is probably built by the 3c and 3d micromeres. The formation of symmetry and the nature of the body axes in the embryo and adult of Platynereis dumerilii are discussed. J. Morphol...
  90. ncbi Cell proliferation dynamics and morphological differentiation during regeneration in Dorvillea bermudensis (Polychaeta, Dorvilleidae)
    Tanja Paulus
    Spezielle Zoologie, Fachbereich Biologie chemie, Universitat Osnabruck, D 49069 Osnabruck, Germany
    J Morphol 267:393-403. 2006
    ....
  91. ncbi CLSM analysis of the phalloidin-stained muscle system in Nerilla antennata, Nerillidium sp. and Trochonerilla mobilis (Polychaeta; Nerillidae)
    Monika C M Müller
    Spezielle Zoologie, Universitat Osnabruck, Germany
    J Morphol 267:885-96. 2006
    ..These results support the belief that absence of circular muscles in the polychaete body wall is much more widely distributed than is currently presumed...
  92. ncbi Chemical signal mediated premating reproductive isolation in a marine polychaete, Neanthes acuminata (arenaceodentata)
    R Sutton
    School of Biosciences, Cardiff University, Park Place, Cardiff, UK
    J Chem Ecol 31:1865-76. 2005
    ..The aggressive display was stronger upon exposure to seawater conditioned with "unrelated" populations and especially between Pacific and Atlantic populations...
  93. ncbi Vertebrate-type intron-rich genes in the marine annelid Platynereis dumerilii
    Florian Raible
    Developmental Unit, European Molecular Biological Laboratory EMBL, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Science 310:1325-6. 2005
    ..A comparison of coding exon sequences confirms the ancestral nature of Platynereis and human genes. Thus, the urbilaterian ancestor had complex, intron-rich genes that have been retained in Platynereis and human...
  94. pmc ParaHox gene expression in larval and postlarval development of the polychaete Nereis virens (Annelida, Lophotrochozoa)
    Milana A Kulakova
    Laboratory of Experimental Embryology, Biological Institute of State University of St Petersburg, Russia
    BMC Dev Biol 8:61. 2008
    ..However, unlike the Hox genes, there is as yet no strong evidence that the ParaHox genes are expressed in spatial and temporal order during embryogenesis...
  95. ncbi Thermal biology of the deep-sea vent annelid Paralvinella grasslei: in vivo studies
    Delphine Cottin
    UPMC Universite Paris 6, UMR 7138, Systématique, Adaptation et Evolution, F 75005 Paris, France
    J Exp Biol 211:2196-204. 2008
    ..Finally, we provide here the first sequences for vent annelid hsp70 (P. grasslei, Hesiolyra bergi and Alvinella pompejana). These constitute valuable tools for future studies on the thermal biology of these annelids...
  96. ncbi Developmental expression of foxA and gata genes during gut formation in the polychaete annelid, Capitella sp. I
    Michael J Boyle
    Kewalo Marine Laboratory, Pacific Biosciences Research Center, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    Evol Dev 10:89-105. 2008
    ..Collectively, the CapI-foxA and CapI-gata genes show patterns of expression that span almost the entire length of the developing alimentary canal, consistent with a role in gut development...
  97. ncbi Larval neurogenesis in Sabellaria alveolata reveals plasticity in polychaete neural patterning
    Nora Brinkmann
    Department of Biology, Research Group for Comparative Zoology, University of Copenhagen, Universitetsparken 15, DK 2100, Copenhagen Ø, Denmark
    Evol Dev 10:606-18. 2008
    ..This highlights the complex mechanisms that underlie annelid body segmentation and indicates divergent developmental pathways within polychaete annelids that lead to the segmented nervous system of the adult...
  98. pmc Annelid phylogeny and the status of Sipuncula and Echiura
    Torsten H Struck
    Auburn University, Life Sciences Department, Auburn, AL 36849, USA
    BMC Evol Biol 7:57. 2007
    ..Traditionally, two major groups are distinguished: Clitellata (including earthworms, leeches) and "Polychaeta" (mostly marine worms)...
  99. pmc atonal- and achaete-scute-related genes in the annelid Platynereis dumerilii: insights into the evolution of neural basic-Helix-Loop-Helix genes
    Elena Simionato
    Evolution et Développement des métazoaires, Centre de Génétique Moléculaire UPR 2167 CNRS, 1, av de terrasse, 91198 Gif sur Yvette, France
    BMC Evol Biol 8:170. 2008
    ....
  100. ncbi Bone-eating Osedax females and their 'harems' of dwarf males are recruited from a common larval pool
    R C Vrijenhoek
    Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, CA 95039, USA
    Mol Ecol 17:4535-44. 2008
    ..Mitochondrial sequence diversity was very high in these worms, suggesting that as many as 10(6) females contributed to a common larval pool from which the two sexes were randomly drawn...
  101. ncbi Hox gene expression in larval development of the polychaetes Nereis virens and Platynereis dumerilii (Annelida, Lophotrochozoa)
    Milana Kulakova
    Laboratory of Experimental Embryology, Biological Institute of State University of St Petersburg, Oranienbaumskoe sh 2, 198504 Starii Petergoff, St Petersburg, Russia
    Dev Genes Evol 217:39-54. 2007
    ....

Research Grants7

  1. Spiralian developmental system for the study of multipotency
    Cesar Arenas Mena; Fiscal Year: 2008
    ..The ultimate goal is to manipulate these genes and reprogram in vivo differentiated cells into multipotent stem cells. [unreadable] [unreadable] [unreadable]..
  2. Multifunctional Nanoparticles for Intracellular Delivery
    Stefan Franzen; Fiscal Year: 2006
    ..5. Develop strategies for covalent attachment of proteins and oligonucleotides to nanoparticles. 6. Determine of the efficiency of regulated in vitro protein expression using a well-characterized model system. ..
  3. CHEMISTRY AND BIOLOGY OF INSULIN-LIKE VANADIUM COMPOUNDS
    DEBBIE CRANS; Fiscal Year: 2003
    ..The proposed studies will lead to an in-depth understanding of both the chemical and pharmacological properties of known and new vanadium compounds inducing insulin-like action. ..
  4. STRUCTURAL BASIS FOR ASSEMBLY OF COOPERATIVE HEMOGLOBINS
    WILLIAM ROYER; Fiscal Year: 2005
    ..Our structural analysis suggests a number of hypotheses for the regulation of function, which we will be testing by mutagenesis, kinetic and structural experiments. ..
  5. Ultrafast Time-Resolved Crystallography on Scapharca Hb
    WILLIAM ROYER; Fiscal Year: 2007
    ..Understanding such principles will aid in the rational manipulation of a number of biological processes. ..
  6. Structural basis of regulation of IRF
    WILLIAM ROYER; Fiscal Year: 2007
    ..These studies will provide insight into the molecular mechanism of IRF signaling, providing possible targets for rational drug design to combat viral pathogenesis. ..
  7. STRUCTURAL STUDIES OF MATRIX PROTEINS IN TEETH AND BONES
    STEPHEN WEINER; Fiscal Year: 2007
    ..abstract_text> ..