peromyscus

Summary

Summary: A genus of the subfamily SIGMODONTINAE consisting of 49 species. Two of these are widely used in medical research. They are P. leucopus, or the white-footed mouse, and P. maniculatus, or the deer mouse.

Top Publications

  1. ncbi Winning fights elevates testosterone levels in California mice and enhances future ability to win fights
    Temitayo O Oyegbile
    Department of Psychology, University of Wisconsin, 1202 West Johnson Street, Madison, WI 53706, USA
    Horm Behav 48:259-67. 2005
  2. pmc Kinetics of immune responses in deer mice experimentally infected with Sin Nombre virus
    Tony Schountz
    School of Biological Sciences, University of Northern Colorado, Greeley, Colorado, USA
    J Virol 86:10015-27. 2012
  3. ncbi Opposing hormonal mechanisms of aggression revealed through short-lived testosterone manipulations and multiple winning experiences
    Brian C Trainor
    Department of Psychology, University of Wisconsin at Madison, Madison, WI 53706, USA
    Horm Behav 45:115-21. 2004
  4. ncbi The genetic basis of phenotypic convergence in beach mice: similar pigment patterns but different genes
    Cynthia C Steiner
    Division of Biological Sciences, University of California, San Diego, USA
    Mol Biol Evol 26:35-45. 2009
  5. pmc Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin
    Jay F Storz
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588, USA
    Proc Natl Acad Sci U S A 106:14450-5. 2009
  6. ncbi Demographic factors associated with prevalence of antibody to Sin Nombre virus in deer mice in the western United States
    Charles H Calisher
    Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Foothills Campus, Colorado State University, Fort Collins, Colorado 80523, USA
    J Wildl Dis 43:1-11. 2007
  7. pmc The molecular basis of high-altitude adaptation in deer mice
    Jay F Storz
    School of Biological Sciences, University of Nebraska, Lincoln, Nebraska, United States of America
    PLoS Genet 3:e45. 2007
  8. ncbi Urban landscape genetics: canopy cover predicts gene flow between white-footed mouse (Peromyscus leucopus) populations in New York City
    Jason Munshi-South
    Department of Natural Sciences, Baruch College, City University of New York CUNY, 17 Lexington Avenue, New York, NY 10010, USA
    Mol Ecol 21:1360-78. 2012
  9. pmc Niche partitioning of Borrelia burgdorferi and Borrelia miyamotoi in the same tick vector and mammalian reservoir species
    Alan G Barbour
    Department of Microbiology and Molecular Genetics, University of California Irvine, Irvine, California 92697 4028, USA
    Am J Trop Med Hyg 81:1120-31. 2009
  10. ncbi Gape and bite force in the rodents Onychomys leucogaster and Peromyscus maniculatus: does jaw-muscle anatomy predict performance?
    Susan H Williams
    Department of Biomedical Sciences, Ohio University College of Osteopathic Medicine, Athens, Ohio 45701, USA
    J Morphol 270:1338-47. 2009

Detail Information

Publications273 found, 100 shown here

  1. ncbi Winning fights elevates testosterone levels in California mice and enhances future ability to win fights
    Temitayo O Oyegbile
    Department of Psychology, University of Wisconsin, 1202 West Johnson Street, Madison, WI 53706, USA
    Horm Behav 48:259-67. 2005
    ..encounters on the likelihood of winning a subsequent aggressive encounter in the California mouse (Peromyscus californicus)...
  2. pmc Kinetics of immune responses in deer mice experimentally infected with Sin Nombre virus
    Tony Schountz
    School of Biological Sciences, University of Northern Colorado, Greeley, Colorado, USA
    J Virol 86:10015-27. 2012
    ..Together, these data suggest that a subtle immune response that fails to clear the virus occurs in deer mice...
  3. ncbi Opposing hormonal mechanisms of aggression revealed through short-lived testosterone manipulations and multiple winning experiences
    Brian C Trainor
    Department of Psychology, University of Wisconsin at Madison, Madison, WI 53706, USA
    Horm Behav 45:115-21. 2004
    ..Previous work has shown that male California mice (Peromyscus californicus) respond to winning aggressive encounters by initiating aggression more quickly in future ..
  4. ncbi The genetic basis of phenotypic convergence in beach mice: similar pigment patterns but different genes
    Cynthia C Steiner
    Division of Biological Sciences, University of California, San Diego, USA
    Mol Biol Evol 26:35-45. 2009
    ..we analyze the molecular mechanisms underlying convergent pigment pattern among subspecies of the beach mouse (Peromyscus polionotus) inhabiting the Gulf and Atlantic coasts of Florida...
  5. pmc Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin
    Jay F Storz
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588, USA
    Proc Natl Acad Sci U S A 106:14450-5. 2009
    ..a combined evolutionary and functional analysis of duplicated globin genes in natural populations of deer mice (Peromyscus maniculatus) that are adapted to different elevational zones...
  6. ncbi Demographic factors associated with prevalence of antibody to Sin Nombre virus in deer mice in the western United States
    Charles H Calisher
    Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Foothills Campus, Colorado State University, Fort Collins, Colorado 80523, USA
    J Wildl Dis 43:1-11. 2007
    ..to be associated with risk of infection with Sin Nombre virus (SNV) in its natural host, the deer mouse (Peromyscus maniculatus)...
  7. pmc The molecular basis of high-altitude adaptation in deer mice
    Jay F Storz
    School of Biological Sciences, University of Nebraska, Lincoln, Nebraska, United States of America
    PLoS Genet 3:e45. 2007
    ..that underlies physiological adaptation to high-altitude hypoxia in natural populations of deer mice, Peromyscus maniculatus...
  8. ncbi Urban landscape genetics: canopy cover predicts gene flow between white-footed mouse (Peromyscus leucopus) populations in New York City
    Jason Munshi-South
    Department of Natural Sciences, Baruch College, City University of New York CUNY, 17 Lexington Avenue, New York, NY 10010, USA
    Mol Ecol 21:1360-78. 2012
    In this study, I examine the influence of urban canopy cover on gene flow between 15 white-footed mouse (Peromyscus leucopus) populations in New York City parklands...
  9. pmc Niche partitioning of Borrelia burgdorferi and Borrelia miyamotoi in the same tick vector and mammalian reservoir species
    Alan G Barbour
    Department of Microbiology and Molecular Genetics, University of California Irvine, Irvine, California 92697 4028, USA
    Am J Trop Med Hyg 81:1120-31. 2009
    ..We used species-specific, quantitative polymerase chain reaction to study both species in the blood and skin of Peromyscus leucopus mice and host-seeking Ixodes scapularis nymphs at a Connecticut site. Bacteremias with B...
  10. ncbi Gape and bite force in the rodents Onychomys leucogaster and Peromyscus maniculatus: does jaw-muscle anatomy predict performance?
    Susan H Williams
    Department of Biomedical Sciences, Ohio University College of Osteopathic Medicine, Athens, Ohio 45701, USA
    J Morphol 270:1338-47. 2009
    Compared with the deer mouse, Peromyscus maniculatus, the grasshopper mouse, Onychomys leucogaster, exhibits modifications in its jaw-muscle architecture that promote wide gapes and large bite forces at wide gapes to prey upon large ..
  11. ncbi Paternal experience suppresses adult neurogenesis without altering hippocampal function in Peromyscus californicus
    Erica R Glasper
    Department of Psychology and Neuroscience Institute, Princeton University, Princeton, New Jersey 08544, USA
    J Comp Neurol 519:2271-81. 2011
    Paternal care is rare among mammals, occurring in ≈6% of species. California mice (Peromyscus californicus) are unusual; fathers participate extensively in raising their young and display the same components of parental care as mothers, ..
  12. pmc The biology and methodology of assisted reproduction in deer mice (Peromyscus maniculatus)
    Monika Veres
    Peromyscus Genetic Stock Center, Department of Biological Sciences, University of South Carolina, Columbia, South Carolina, USA
    Theriogenology 77:311-9. 2012
    Although laboratory-reared species of the genus Peromyscus-including deer mice-are used as model animals in a wide range of research, routine manipulation of Peromyscus embryogenesis and reproduction has been lagging...
  13. ncbi Schistosome infection in deer mice (Peromyscus maniculatus): impacts on host physiology, behavior and energetics
    Lisa E Schwanz
    Department of Biology, University of New Mexico, Albuquerque, NM 87109, USA
    J Exp Biol 209:5029-37. 2006
    ..The present study examined the effects of a trematode parasite, Schistosomatium douthitti, on deer mouse (Peromyscus maniculatus) physiology, behavior and energetics...
  14. pmc Adaptive significance of male parental care in a monogamous mammal
    D J Gubernick
    Hastings Natural History Reservation, Carmel Valley, CA 93924, USA
    Proc Biol Sci 267:147-50. 2000
    ..that paternal behaviour enhances offspring survival in a monogamous mammal, the biparental California mouse, Peromyscus californicus. Male removal resulted in lower offspring survival in father-absent than in father-present families...
  15. pmc Photoperiod-mediated impairment of long-term potention and learning and memory in male white-footed mice
    J C Walton
    Department of Neuroscience, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Neuroscience 175:127-32. 2011
    ..White-footed mice (Peromyscus leucopus) are particularly well suited to investigate brain plasticity because they show marked seasonal changes ..
  16. pmc Competition drives cooperation among closely related sperm of deer mice
    Heidi S Fisher
    Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, Cambridge, Massachusetts 02138, USA
    Nature 463:801-3. 2010
    ..Here we show that sperm of deer mice (genus Peromyscus) form motile aggregations, then we use this system to test predictions of sperm cooperation...
  17. pmc Genetic differences in hemoglobin function between highland and lowland deer mice
    Jay F Storz
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588, USA
    J Exp Biol 213:2565-74. 2010
    ..genetically based differences in Hb-O(2) affinity between highland and lowland populations of the deer mouse (Peromyscus maniculatus), a generalist species that has the broadest altitudinal distribution of any North American mammal...
  18. ncbi Could parasites destabilize mouse populations? The potential role of Pterygodermatites peromysci in the population dynamics of free-living mice, Peromyscus leucopus
    Kurt J Vandegrift
    Center for Infectious Disease Dynamics, Biology Department, 208 Mueller Laboratory, Pennsylvania State University, University Park, PA 16802, USA
    Int J Parasitol 39:1253-62. 2009
    b>Peromyscus leucopus populations exhibit unstable population dynamics...
  19. pmc Effects of spatially varying selection on nucleotide diversity and linkage disequilibrium: insights from deer mouse globin genes
    Jay F Storz
    School of Biological Sciences, University of Nebraska, Lincoln, Nebraska 68588, USA
    Genetics 180:367-79. 2008
    ..of a multilocus survey of nucleotide diversity and LD between high- and low-altitude populations of deer mice, Peromyscus maniculatus...
  20. pmc Winning territorial disputes selectively enhances androgen sensitivity in neural pathways related to motivation and social aggression
    Matthew J Fuxjager
    Department of Zoology, University of Wisconsin, Madison, WI 53706, USA
    Proc Natl Acad Sci U S A 107:12393-8. 2010
    ..We examined this issue in the territorial California mouse (Peromyscus californicus) because males of this species are more likely to win fights after accruing victories in their home ..
  21. ncbi Pathogenesis of experimental vesicular stomatitis virus (New Jersey serotype) infection in the deer mouse (Peromyscus maniculatus)
    T E Cornish
    Department of Veterinary Pathology, College of Veterinary Medicine, University of Georgia, Athens, USA
    Vet Pathol 38:396-406. 2001
    ..In the present study, 45 juvenile and 80 adult deer mice (Peromyscus maniculatus) were inoculated intranasally with VSV New Jersey serotype (VSV-NJ) and examined sequentially over a ..
  22. ncbi Rapid morphological and genetic change in Chicago-area Peromyscus
    Oliver R W Pergams
    Department of Biological Sciences, University of Illinois at Chicago, 845 W Taylor St, Chicago, IL 60607 USA
    Mol Ecol 17:450-63. 2008
    We report rapid change of morphology and mitochondrial genes in white-footed mice (Peromyscus leucopus) in the Chicago (Illinois, USA) region...
  23. pmc Gatm, a creatine synthesis enzyme, is imprinted in mouse placenta
    Lisa L Sandell
    Howard Hughes Medical Institute and Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 100:4622-7. 2003
    ..This genomic screen for novel imprinted genes has elucidated a new connection between imprinting and creatine metabolism during embryonic development in mammals...
  24. ncbi Nuclear and mitochondrial DNA reveal contrasting evolutionary processes in populations of deer mice (Peromyscus maniculatus)
    Dou Shuan Yang
    Burke Museum and Department of Biology, University of Washington, Seattle, 98195, USA
    Mol Ecol 18:5115-25. 2009
    We investigated a major geographic break in mitochondrial DNA (mtDNA) haplotypes in deer mice, Peromyscus maniculatus, by analysing spatial variation in a 491-bp fragment of the mtDNA control region from 455 samples distributed across a ..
  25. pmc Contact heterogeneity in deer mice: implications for Sin Nombre virus transmission
    Christine A Clay
    Department of Biology, Westminster College, 1840 South 1300 East, Salt Lake City, UT 84105, USA
    Proc Biol Sci 276:1305-12. 2009
    ..rates among potential hosts of a directly transmitted pathogen by examining Sin Nombre virus (SNV) in deer mice (Peromyscus maniculatus)...
  26. ncbi Antibody to sin nombre virus in rodents associated with peridomestic habitats in west central Montana
    A J Kuenzi
    Department of Biology, Montana Tech of the University of Montana, Butte 59701, USA
    Am J Trop Med Hyg 64:137-46. 2001
    ..environment, yet studies of the ecology and infection dynamics in the reservoir host, the deer mouse (Peromyscus maniculatus), have focused on sylvan populations. We describe a 2...
  27. pmc The Dlk1 and Gtl2 genes are linked and reciprocally imprinted
    J V Schmidt
    Howard Hughes Medical Institute and Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA
    Genes Dev 14:1997-2002. 2000
    ..Dlk1 and Gtl2 are coexpressed and respond in a reciprocal manner to loss of DNA methylation. These genes are likely to represent a new example of coordinated imprinting of linked genes...
  28. ncbi Parasites prevent summer breeding in white-footed mice, Peromyscus leucopus
    Kurt J Vandegrift
    Center for Infectious Disease Dynamics, Biology Department, Mueller Laboratory, Penn State University, University Park, Pennsylvania 16802, USA
    Ecology 89:2251-8. 2008
    ..We examined the role of these factors on the vital rates of free-living white-footed mice (Peromyscus leucopus) over the summer and autumn months...
  29. ncbi How host population dynamics translate into time-lagged prevalence: an investigation of Sin Nombre virus in deer mice
    Frederick R Adler
    Department of Mathematics and Department of Biology, 155 South 1400 East, University of Utah, Salt Lake City, UT 84112, USA
    Bull Math Biol 70:236-52. 2008
    ..Population size variation due to variation in birth rates rather than death rates also increases the lag. Predicting future human outbreaks of hantavirus pulmonary syndrome may require taking these effects into account...
  30. ncbi Analyses of gene flow among populations of deer mice (Peromyscus maniculatus) at sites near hantavirus pulmonary syndrome case-patient residences
    J Jeffrey Root
    Department of Microbiology AIDL, Colorado State University, Fort Collins, Colorado 80523, USA
    J Wildl Dis 39:287-98. 2003
    Gene flow and potential for Sin Nombre virus (SNV) trafficking of the deer mouse (Peromyscus maniculatus) was studied in Delta and Mesa counties of western Colorado (USA)...
  31. ncbi Testosterone and photoperiod interact to affect spatial learning and memory in adult male white-footed mice (Peromyscus leucopus)
    Leah M Pyter
    Department of Neuroscience, and Institute of Behavioural Medicine Research, Ohio State University, Columbus, 43210, USA
    Eur J Neurosci 23:3056-62. 2006
    ..concentration, short days also impair spatial learning and memory performance in male white-footed mice (Peromyscus leucopus) compared with long days...
  32. ncbi Effects of genetic captive-breeding protocols on sperm quality and fertility in the white-footed mouse
    Aurelio F Malo
    Center for Conservation and Evolutionary Genetics, National Zoological Park, Smithsonian Institution, Washington, DC, USA
    Biol Reprod 83:540-8. 2010
    Mice (Peromyscus leucopus noveboracensis) from a captive-breeding program were used to test the effects of three genetic breeding protocols (minimizing mean kinship [MK], random breeding, and selection for docility [DOC]) and inbreeding ..
  33. ncbi Sin Nombre hantavirus decreases survival of male deer mice
    Angela D Luis
    Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, PA, USA
    Oecologia 169:431-9. 2012
    ....
  34. ncbi Alterations in immune function and CYP450 activity in adult male deer mice (Peromyscus maniculatus) following exposure to benzo[a]pyrene, pyrene, or chrysene
    M M Peden-Adams
    Department of Pediatrics and the Marine Biomedicine and Environmental Science Center, Medical University of South Carolina, Charleston, South Carolina 29412, USA
    J Toxicol Environ Health A 70:1783-91. 2007
    ..Deer mice (Peromyscus maniculatus) exhibit a wide geographic distribution throughout North America and have been suggested as a ..
  35. ncbi Effects of heavy metals on immunocompetence of white-footed mice (Peromyscus leucopus)
    Jennifer A Biser
    Department of Biological Sciences, Campus Box 4120, Illinois State University, Normal, Illinois 61790 4120, USA
    J Wildl Dis 40:173-84. 2004
    ..study conducted from May 1999 through May 2001, we examined assays of immnnoompetence in the white-footed mouse (Peromyscus leucopus) that inhabited reference sites and sites significantly contaminated with mixtures of heavy metals...
  36. ncbi A single amino acid mutation contributes to adaptive beach mouse color pattern
    Hopi E Hoekstra
    Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA
    Science 313:101-4. 2006
    ..Here, we link a single mutation in the coding region of a pigmentation gene to adaptive quantitative variation in the wild...
  37. ncbi Responses to lactation and cold exposure by deer mice (Peromyscus maniculatus)
    K A Hammond
    Department of Biology, University of California, Riverside, CA 92521, USA
    Physiol Biochem Zool 73:547-56. 2000
    ..We set out to learn (i) whether female deer mice (Peromyscus maniculatus) given lactation (two to seven pups per litter), cold (5 degrees C), or cold plus lactation as ..
  38. ncbi Morphological and physiological responses to altitude in deer mice Peromyscus maniculatus
    K A Hammond
    Department of Biology, University of California, Riverside, CA, 92521, USA
    Physiol Biochem Zool 72:613-22. 1999
    ..gradient? We measured food intake, resting metabolic rate (RMR), and organ mass in captive deer mice (Peromyscus maniculatus bairdii) at three sites from 1,200 to 3,800 m above sea level to determine whether energy demand was ..
  39. ncbi Borrelia burgdorferi has minimal impact on the Lyme disease reservoir host Peromyscus leucopus
    Lisa E Schwanz
    Cary Institute of Ecosystem Studies, Millbrook, New York, USA
    Vector Borne Zoonotic Dis 11:117-24. 2011
    ..the etiological agent of Lyme disease, on one of its most important reservoir hosts, the white-footed mouse, Peromyscus leucopus...
  40. ncbi Antibodies to whole-cell or recombinant antigens of Borrelia burgdorferi, Anaplasma phagocytophilum, and Babesia microti in white-footed mice
    Louis A Magnarelli
    Department of Entomology, The Connecticut Agricultural Experiment Station, PO Box 1106, New Haven, Connecticut 06504, USA
    J Wildl Dis 42:732-8. 2006
    Serum samples were obtained from white-footed mice (Peromyscus leucopus) in tick-infested areas of Connecticut during the period 2001 through 2003 and analyzed for antibodies to Borrelia burgdorferi, Anaplasma phagocytophilum, and Babesia ..
  41. pmc A comparison of scent marking between a monogamous and promiscuous species of peromyscus: pair bonded males do not advertise to novel females
    Elizabeth A Becker
    Department of Psychology, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 7:e32002. 2012
    ..We compared the highly territorial and monogamous California mouse (Peromyscus californicus) to the less territorial and promiscuous white-footed mouse (P. leucopus)...
  42. ncbi Changes in sin nombre virus antibody prevalence in deer mice across seasons: the interaction between habitat, sex, and infection in deer mice
    Jessica M C Pearce-Duvet
    Biology Department, University of Utah, 257 South 1400 East, Salt Lake City, UT 84112, USA
    J Wildl Dis 42:819-24. 2006
    We examined the impact of season and habitat on Sin Nombre virus (SNV) seroprevalence in deer mice (Peromyscus maniculatus) in Utah's Great Basin Desert from May 2002 through summer 2003...
  43. ncbi Age and aerobic performance in deer mice
    Mark A Chappell
    Department of Biology, University of California, Riverside, CA 92521, USA
    J Exp Biol 206:1221-31. 2003
    ..a cross-sectional study of age effects on body composition, aerobic performance and ventilation in deer mice Peromyscus maniculatus...
  44. ncbi Borrelia burgdorferi infection in a natural population of Peromyscus Leucopus mice: a longitudinal study in an area where Lyme Borreliosis is highly endemic
    Jonas Bunikis
    Department of Microbiology and Molecular Genetics, University of California Irvine, Irvine, California 92697 4025, USA
    J Infect Dis 189:1515-23. 2004
    Blood samples from Peromyscus leucopus mice captured at an enzootic site in Connecticut were examined for antibodies to and DNA of Borrelia burgdorferi, to characterize the dynamics of infection in this reservoir population...
  45. ncbi The progesterone challenge: steroid hormone changes following a simulated territorial intrusion in female Peromyscus californicus
    Ellen S Davis
    Department of Psychology, University of Wisconsin, Madison, WI 53706, USA
    Horm Behav 44:185-98. 2003
    ..We conducted 10-min aggression trials using the resident-intruder paradigm in cycling female California mice, Peromyscus californicus, a species in which both sexes show territorial behavior...
  46. ncbi Immune response, not immune maintenance, is energetically costly in wild white-footed mice (Peromyscus leucopus)
    Terry L Derting
    Department of Biological Sciences, Murray State University, Murray, KY, 42071 3346, USA
    Physiol Biochem Zool 76:744-52. 2003
    ..a normally functioning immune system and mounting a mild immune response in wild male white-footed mice (Peromyscus leucopus)...
  47. ncbi Seasonal variation in Sin Nombre virus infections in deer mice: preliminary results
    M Denise Dearing
    Department of Biology, University of Utah, Salt Lake City, Utah, USA
    J Wildl Dis 45:430-6. 2009
    The proportion of deer mice (Peromyscus maniculatus) with recently acquired Sin Nombre virus (SNV) infections is an indicator of epizootic intensity and may be key in predicting outbreaks of hantavirus cardio-pulmonary syndrome in humans...
  48. ncbi Enrichment and photoperiod interact to affect spatial learning and hippocampal dendritic morphology in white-footed mice (Peromyscus leucopus)
    Joanna L Workman
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Eur J Neurosci 29:161-70. 2009
    ..Specifically, short days impair spatial learning in white-footed mice (Peromyscus leucopus) and alter dendritic complexity in the hippocampus...
  49. ncbi The effect of unsaturated and saturated dietary lipids on the pattern of daily torpor and the fatty acid composition of tissues and membranes of the deer mouse Peromyscus maniculatus
    F Geiser
    Department of Zoology, University of New England, Armidale, New South Wales, Australia
    J Comp Physiol B 161:590-7. 1991
    ..Deer mice, Peromyscus maniculatus, were fed with rodent chow (control diet) or rodent chow with either 10% sunflower seed oil (..
  50. ncbi Microbial ecological response of the intestinal flora of Peromyscus maniculatus and P. leucopus to heavy metal contamination
    Joseph D Coolon
    Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, 48109, USA
    Mol Ecol 19:67-80. 2010
    ..Using bar-coded, massively parallel sequencing, we found that bacterial communities in both the soil and Peromyscus spp...
  51. pmc Genetic diversity of Borrelia burgdorferi sensu stricto in Peromyscus leucopus, the primary reservoir of Lyme disease in a region of endemicity in southern Maryland
    Jennifer M Anderson
    The W Harry Feinstone Department of Molecular Microbiology and Immunology, John Hopkins Bloomberg, School of Public Health, Baltimore, MD 21205, USA
    Appl Environ Microbiol 72:5331-41. 2006
    ..LD), is maintained in an enzootic cycle between the vector, Ixodes scapularis, and the primary reservoir host, Peromyscus leucopus...
  52. ncbi From here to paternity: neural correlates of the onset of paternal behavior in California mice (Peromyscus californicus)
    Trynke R de Jong
    Department of Biology, 3386 Spieth Hall, University of California, Riverside, Riverside, CA 92527, USA
    Horm Behav 56:220-31. 2009
    ..Fatherhood also appears to alter neurotransmission in the BNST and DRC, regions implicated in emotionality and stress-responsiveness...
  53. ncbi Testosterone release and social context: when it occurs and why
    Erin D Gleason
    University of Wisconsin Madison, Department of Psychology, 1202 West Johnson St, Madison, WI 53706, USA
    Front Neuroendocrinol 30:460-9. 2009
    ..Many studies, including those with California mice (Peromyscus californicus), have addressed these issues using manipulations and species comparisons, but many areas remain to ..
  54. pmc Experimental infections of the reservoir species Peromyscus leucopus with diverse strains of Borrelia burgdorferi, a Lyme disease agent
    ELISABETH BAUM
    Departments of Microbiology and Molecular Genetics, Medicine, and Ecology and Evolutionary Biology, University of California, Irvine, CA, USA
    MBio 3:e00434-12. 2012
    The rodent Peromyscus leucopus is a major natural reservoir for the Lyme disease agent Borrelia burgdorferi and a host for its vector Ixodes scapularis. At various locations in northeastern United States 10 to 15 B...
  55. ncbi Vector competence of Ixodes pacificus and I. spinipalpis (Acari: Ixodidae), and reservoir competence of the dusky-footed woodrat (Neotoma fuscipes) and the deer mouse (Peromyscus maniculatus), for Borrelia bissettii
    Lars Eisen
    Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720, USA
    J Med Entomol 40:311-20. 2003
    ..Nuttall, and the reservoir competence of the dusky-footed woodrat (Neotoma fuscipes Baird) and the deer mouse (Peromyscus maniculatus [Wagner]), for Borrelia bissettii Postic, Marti Ras, Lane, Hendson, and Baranton...
  56. pmc Paternal responsiveness is associated with, but not mediated by reduced neophobia in male California mice (Peromyscus californicus)
    Miyetani Chauke
    Neuroscience Graduate Program, University of California, Riverside, CA 92521, USA
    Physiol Behav 107:65-75. 2012
    ..To determine whether the onset of paternal behavior has similar associations in biparental male California mice (Peromyscus californicus), we compared paternal responsiveness, neophobia (novel-object test), and anxiety-like behavior (..
  57. pmc Sex and dose-dependent effects of developmental exposure to bisphenol A on anxiety and spatial learning in deer mice (Peromyscus maniculatus bairdii) offspring
    Eldin Jasarević
    Interdisciplinary Neuroscience Program, Center for Translational Neuroscience, University of Missouri, Columbia, MO 65211, USA
    Horm Behav 63:180-9. 2013
    ..Outbred deer mice (Peromyscus maniculatus bairdii) are an excellent animal model for such studies as they exhibit well-defined sex- and ..
  58. pmc Population density and seasonality effects on Sin Nombre virus transmission in North American deermice (Peromyscus maniculatus) in outdoor enclosures
    Karoun H Bagamian
    Population Biology, Ecology, and Evolution Program, Emory University, Atlanta, Georgia, United States of America
    PLoS ONE 7:e37254. 2012
    ..Using outdoor enclosures, we tested effects of North American deermouse (Peromyscus maniculatus) population density and season on transmission dynamics of Sin Nombre hantavirus...
  59. pmc Infection with agents of human granulocytic ehrlichiosis, lyme disease, and babesiosis in wild white-footed mice (Peromyscus leucopus) in Connecticut
    K C Stafford
    The Connecticut Agricultural Experiment Station, New Haven, Connecticut 06504, USA
    J Clin Microbiol 37:2887-92. 1999
    White-footed mice, Peromyscus leucopus, were captured in southern Connecticut during 1997 and 1998 to determine the prevalence of infections caused by granulocytic Ehrlichia sp., Borrelia burgdorferi, and Babesia microti...
  60. ncbi Cranial shape varies along an elevation gradient in Gambel's white-footed mouse (Peromyscus maniculatus gambelii) in the Grinnell Resurvey Yosemite transect
    T M Grieco
    Department of Integrative Biology, University of California at Berkeley, Berkeley, California 94720, USA
    J Morphol 271:897-909. 2010
    ..along a transect sampled in the Grinnell Resurvey project to determine whether Gambel's white-footed mouse (Peromyscus maniculatus gambelii), a generalist taxon inhabiting the full elevational range of habitats in Yosemite National ..
  61. ncbi Genetic correlation between resting metabolic rate and exploratory behaviour in deer mice (Peromyscus maniculatus)
    V Careau
    Departement de Biologie, Universite de Sherbrooke, Sherbrooke, QC, Canada
    J Evol Biol 24:2153-63. 2011
    ..78 ± 0.23). Our results suggest that RMR and exploratory behaviour are functionally integrated traits in deer mice, providing empirical support for one of the connections within the pace-of-life syndrome hypothesis...
  62. ncbi Weak winner effect in a less aggressive mammal: correlations with corticosterone but not testosterone
    Temitayo O Oyegbile
    Department of Psychology, 1202 West Johnson Street, University of Wisconsin, Madison, WI, 53706, United States
    Physiol Behav 89:171-9. 2006
    ..encounter following previous victories) and an associated rise in testosterone (T) in the white-footed mouse (Peromyscus leucopus) which generally display low levels of aggression and territoriality...
  63. ncbi Short photoperiods evoke testicular apoptosis in white-footed mice (Peromyscus leucopus)
    K A Young
    Department of Biochemistry, School of Public Health, The Johns Hopkins University, Baltimore, Maryland 21218, USA
    Endocrinology 140:3133-9. 1999
    ..Male white-footed mice (Peromyscus leucopus) exposed to inhibitory short day lengths provide a natural animal model to study the cellular ..
  64. ncbi Genealogical concordance and the specific status of Peromyscus sejugis
    Mindy L Walker
    Department of Biology, Texas A and M University, College Station, TX 77843, USA
    J Hered 97:340-5. 2006
    b>Peromyscus sejugis, a peripheral isolate of Peromyscus maniculatus, is a threatened taxon endemic to 2 small islands in the Sea of Cortés. Although its insularity makes the specific recognition of P...
  65. ncbi Reproductive effects of hexahydro-1,3,5-trinitroso-1,3,5-triazine in deer mice (Peromyscus maniculatus) during a controlled exposure study
    Jordan N Smith
    The Institute of Environmental and Human Health TIEHH, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    Environ Toxicol Chem 25:446-51. 2006
    ..Following exposure, reproductive toxicity of TNX was evaluated in three consecutive litters of deer mice (Peromyscus maniculatus)...
  66. ncbi Photoperiod-induced differential expression of angiogenesis genes in testes of adult Peromyscus leucopus
    Leah M Pyter
    Neuroscience and Psychology, Ohio State University, Columbus, OH 43210, USA
    Reproduction 129:201-9. 2005
    ..We compared the patterns of gene expression involved in angiogenesis in testes of white-footed mice (Peromyscus leucopus) following 7, 14, 21 or 34 weeks of long or short day lengths...
  67. pmc Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus
    Nazar Labinskyy
    Department of Physiology, New York Medical College, Valhalla, New York, USA
    Am J Physiol Heart Circ Physiol 296:H946-56. 2009
    ..We tested this hypothesis using two taxonomically related rodents, the white-footed mouse (Peromyscus leucopus) and the house mouse (Mus musculus), which show a more than twofold difference in maximum lifespan ..
  68. ncbi Modulation of endocrine pathways by 4,4'-DDE in the deer mouse Peromyscus maniculatus
    R L Dickerson
    Texas Tech University Texas Tech University Health Sciences Center, Lubbock 79430, USA
    Sci Total Environ 233:97-108. 1999
    ..These results indicate that environmentally-relevant levels of 4,4'-DDE modulate the activity and expression of CYP1A1 and phase II enzymes in the deer mouse and that certain changes may be measured non-lethally...
  69. ncbi Short photoperiods reduce vascular endothelial growth factor in the testes of Peromyscus leucopus
    K A Young
    Department of Biochemistry and Molecular Biology, Division of Reproductive Biology, The Johns Hopkins University, Baltimore, Maryland 21218, USA
    Am J Physiol Regul Integr Comp Physiol 279:R1132-7. 2000
    ..To discriminate between these hypotheses, white-footed mice (Peromyscus leucopus) were maintained in either long (LD 16:8) or short (LD 8:16) photoperiod...
  70. ncbi Testicular histopathology in deer mice (Peromyscus maniculatus) following exposure to polychlorinated biphenyl
    Dawn A Alston
    Spelman College, 350 Spelman Lane Southwest, Atlanta, GA 30314 4399, USA
    Chemosphere 52:283-5. 2003
    ..is highly destructive to seminiferous tubules, and that these histological alterations undoubtedly are responsible for the depressed fertility in Peromyscus following chronic exposure to PCBs, that has been reported in the literature.
  71. ncbi Immunological and physiological effects of chronic exposure of Peromyscus leucopus to Aroclor 1254 at a concentration similar to that found at contaminated sites
    Mariangela Segre
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Illinois, 2001 South Lincoln Avenue, Urbana 61802, USA
    Toxicology 174:163-72. 2002
    ..Previously, we found that 4 and 6-week-old white-footed mice (Peromyscus leucopus) born from dams injected with a single dose (300 mg/kg) of Aroclor 1254, had altered immunological, ..
  72. ncbi Age dependent acute oral toxicity of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and two anaerobic N-nitroso metabolites in deer mice (Peromyscus maniculatus)
    Jordan N Smith
    The Institute of Environmental and Human Health, The Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409, USA
    Chemosphere 67:2267-73. 2007
    ..Median lethal dose (LD50) was determined in deer mice (Peromyscus maniculatus) of three age classifications 21 d, 50 d, and 200 d for RDX, MNX, and TNX using the US EPA up-and-..
  73. ncbi Independent and additive contributions of postvictory testosterone and social experience to the development of the winner effect
    Matthew J Fuxjager
    University of Wisconsin Madison, Department of Zoology, 250 North Mills Street, Madison, Wisconsin 53706, USA
    Endocrinology 152:3422-9. 2011
    ..Here, we use the territorial California mouse (Peromyscus californicus) to investigate how the effects of postvictory testosterone (T) release and winning experience ..
  74. pmc HPA activity and neotic and anxiety-like behavior vary among Peromyscus species
    Lynn B Martin
    Departments of Psychology, Neuroscience, and Evolution, Ecology, and Organismal Biology, The Ohio State University, Columbus, OH 43210, USA
    Gen Comp Endocrinol 151:342-50. 2007
    ..Some species of mice in the genus, Peromyscus, occupy most of North America whereas others are restricted to small areas...
  75. ncbi Effect of resource availability on biparental care, and offspring neural and behavioral development in the California mouse (Peromyscus californicus)
    Timothy W Bredy
    Department of Psychiatry and Biobehavioral Sciences, UCLA, Los Angeles, CA 90095, USA
    Eur J Neurosci 25:567-75. 2007
    ..Together, the results suggest that resource availability affects biparental investment strategies, with subsequent effects on hippocampal development and novel object recognition in the offspring...
  76. ncbi A unique late-replicating XY to autosome translocation in Peromyscus melanophrys
    Elisabeth E Mlynarski
    Department of Molecular and Cell Biology, University of Connecticut, Storrs, 06269, USA
    Chromosome Res 18:179-89. 2010
    We report on the characterization of the Peromyscus melanophrys karyotype and sex chromosome system...
  77. ncbi Congenital transmission of Toxoplasma gondii in deer mice (Peromyscus maniculatus) after oral oocyst infection
    Daniel Rejmanek
    Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, California 95616, USA
    J Parasitol 96:516-20. 2010
    ..routes of Toxoplasma gondii transmission influence the antibody response and infection status of deer mice (Peromyscus maniculatus), 80 mice were orally infected with 1, 5, 10, or 100 T. gondii oocysts...
  78. ncbi N-Nitroso compounds produced in deer mouse (Peromyscus maniculatus) GI tracts following hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) exposure
    Xiaoping Pan
    The Institute of Environmental and Human Health, Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409 1163, USA
    Chemosphere 67:1164-70. 2007
    ..DNX in stomach were 217 microg/kg for the 10mg/kg dose group and 498 microg/kg for the 100mg/kg dose group. Changes in other toxic endpoints including body weight gain, food consumption, organ weight, and behavior were also reported...
  79. pmc Delayed density-dependent prevalence of Sin Nombre virus infection in deer mice (Peromyscus maniculatus) in central and western Montana
    Scott Carver
    Department of Biology, Montana Tech of University of Montana, 1300 Park Street, Butte, Montana 59701, USA
    J Wildl Dis 47:56-63. 2011
    ..of zoonoses takes place within reservoir populations, such as Sin Nombre virus (SNV) among deer mice (Peromyscus maniculatus), is important in determining the risk of exposure to other hosts, including humans...
  80. ncbi Prolonged separation delays wound healing in monogamous California mice, Peromyscus californicus, but not in polygynous white-footed mice, P. leucopus
    Lynn B Martin
    Department of Psychology and Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH 43210, USA
    Physiol Behav 87:837-41. 2006
    ..In a previous study, wound healing was slowed after mate separation (2 days) in monogamous California mice, Peromyscus californicus, but not polygynous white-footed mice, P. leucopus...
  81. ncbi Heavy metal exposure, reproductive activity, and demographic patterns in white-footed mice (Peromyscus leucopus) inhabiting a contaminated floodplain wetland
    Jeffrey M Levengood
    Division of Ecology and Conservation Science, Illinois Natural History Survey, 1816 S Oak St, Champaign IL 61820, USA
    Sci Total Environ 389:320-8. 2008
    We examined the concentrations of selected metals and selenium (Se) in the tissues of white-footed mice (Peromyscus leucopus) collected at a constructed wetland originally created as a retention basin for sediments dredged from Lake DePue,..
  82. ncbi Effects of dietary PCB exposure on reproduction in the white-footed mouse (Peromyscus leucopus)
    M B Voltura
    Patuxent Wildlife Research Center, United States Geological Survey, 11510 American Holly Drive, Laurel, Maryland 20708, USA
    Arch Environ Contam Toxicol 52:264-9. 2007
    ..We fed successfully breeding female white-footed mice (Peromyscus leucopus) diets containing polychlorinated biphenyls (2:1 Aroclor 1242:1254) at levels of 0 (n = 10), 10 (n = 12)..
  83. pmc Social and photoperiod effects on reproduction in five species of Peromyscus
    Brian C Trainor
    Department of Psychology, Ohio State University, Columbus, OH 43210, USA
    Gen Comp Endocrinol 148:252-9. 2006
    ..We hypothesized that individuals of different species of Peromyscus mice found closer to the equator would respond more strongly to housing with an opposite sex conspecific than ..
  84. ncbi Population dynamics of a generalist rodent in relation to variability in pulsed food resources in a fragmented landscape
    Gregg J Marcello
    Department of Zoology, Miami University, OH 45056, USA
    J Anim Ecol 77:41-6. 2008
    ..had similar effects on the population dynamics of a generalist forest rodent, Peromyscus leucopus, as have been reported for a cacheable pulsed resource (acorn mast). 3...
  85. ncbi Immune defense and reproductive pace of life in Peromyscus mice
    Lynn B Martin
    Department of Psychology, Ohio State University, Columbus, Ohio 43210, USA
    Ecology 88:2516-28. 2007
    ..In the present study, we tested the hypothesis that immune defense among captive-bred, disease-free Peromyscus mice would be influenced by their reproductive life history strategies...
  86. ncbi Response to enrichment, type and timing: small mammals vary in their response to a springtime cicada but not a carbohydrate pulse
    Kurt J Vandegrift
    Center for Infectious Disease Dynamics, Pennsylvania State University, University Park, PA 16802, USA
    J Anim Ecol 78:202-9. 2009
    ..field experiment and capture-mark-recapture techniques to record the vital rates, demographics, and abundance of Peromyscus leucopus (the white-footed mouse), as well as other small mammals and their parasites. 3. The density of P...
  87. ncbi Acorn mast drives long-term dynamics of rodent and songbird populations
    Ethan D Clotfelter
    Department of Biology, Amherst College, Amherst, MA 01002, USA
    Oecologia 154:493-503. 2007
    ..alba), abundance of white-footed mice (Peromyscus leucopus) and deer mice (P...
  88. ncbi Reproductive protein evolution within and between species: maintenance of divergent ZP3 alleles in Peromyscus
    Leslie M Turner
    Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093, USA
    Mol Ecol 17:2616-28. 2008
    ..Here we investigate the molecular population genetics of the protein ZP3 within two Peromyscus species...
  89. ncbi Cosegregation of a novel Bartonella species with Borrelia burgdorferi and Babesia microti in Peromyscus leucopus
    E K Hofmeister
    Department of Laboratory Medicine and Pathology, Mayo Foundation, Rochester, Minnesota 55905, USA
    J Infect Dis 177:409-16. 1998
    ..Further analysis of Peromyscus leucopus blood and tissue samples demonstrated that the novel Bartonella species was exclusively found in ..
  90. ncbi Giving-updensity and dietary shifts in the white-footed mouse, Peromyscus leucopus
    Pei Jen Shaner
    Department of Environmental Sciences, University of Virginia, Charlottesville, Virginia 22904, USA
    Ecology 88:87-95. 2007
    ..tested the effects of complementary resources on dietary shifts of an omnivorous mammal, the white-footed mouse Peromyscus leucopus, in the context of depletable food patches in the natural environment...
  91. pmc Activation of extracellular signal-regulated kinases in social behavior circuits during resident-intruder aggression tests
    B C Trainor
    Department of Psychology, University of California, Davis, CA 95616, USA
    Neuroscience 165:325-36. 2010
    ..photoperiod on phosphorylation of extracellular signal-regulated kinases 1 and 2 (ERK) in male California mice (Peromyscus californicus) during resident-intruder tests...
  92. pmc Sex differences in hormonal responses to social conflict in the monogamous California mouse
    Brian C Trainor
    Department of Psychology, University of California, Davis, CA 95616, USA
    Horm Behav 58:506-12. 2010
    ..We examined the stress hormone responses of monogamous California mice (Peromyscus californicus) to resident-intruder tests...
  93. ncbi Divergent genetic and epigenetic post-zygotic isolation mechanisms in Mus and Peromyscus
    U Zechner
    Max Planck Institute for Molecular Genetics, Ihnestrasse, Berlin, Germany
    J Evol Biol 17:453-60. 2004
    Interspecific hybridization in the rodent genera Peromyscus and Mus results in abnormal placentation...
  94. pmc Comparative genome mapping of the deer mouse (Peromyscus maniculatus) reveals greater similarity to rat (Rattus norvegicus) than to the lab mouse (Mus musculus)
    Clifton M Ramsdell
    Department of Genetics and the Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    BMC Evol Biol 8:65. 2008
    Deer mice (Peromyscus maniculatus) and congeneric species are the most common North American mammals. They represent an emerging system for the genetic analyses of the physiological and behavioral bases of habitat adaptation...
  95. ncbi Chain reactions linking acorns to gypsy moth outbreaks and Lyme disease risk
    C G Jones
    Institute of Ecosystem Studies IES, Post Office Box AB, Millbrook, NY 12545, USA
    Science 279:1023-6. 1998
    ..Mice are primarily responsible for infecting ticks with the Lyme disease agent. The results have important implications for predicting and managing forest health and human health...
  96. ncbi A direct repeat sequence at the Rasgrf1 locus and imprinted expression
    R S Pearsall
    Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York, 14263 0001, USA
    Genomics 55:194-201. 1999
    ..A more divergent rodent species (Peromyscus) appears to lack a similar repeat structure based on Southern Blot analysis...
  97. pmc Mapping and identification of candidate loci responsible for Peromyscus hybrid overgrowth
    Maria Loschiavo
    Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, CA 92799, USA
    Mamm Genome 18:75-85. 2007
    Crosses between two recently diverged rodent species of the genus Peromyscus result in dramatic parent-of-origin effects on growth and development. P. maniculatus females crossed with P...
  98. pmc Persistent Sin Nombre virus infection in the deer mouse (Peromyscus maniculatus) model: sites of replication and strand-specific expression
    Jason Botten
    Infectious Diseases and Inflammation Program, University of New Mexico, Albuquerque 87131, USA
    J Virol 77:1540-50. 2003
    ..Virus could be isolated consistently only from mice that demonstrated the disseminated pattern. The heart, lung, and BAT are important sites for the replication and maintenance of SN virus during persistent infection...
  99. ncbi Heritable, diet-induced hyperlipidemia in California mice (Peromyscus californicus) is due to increased hepatic secretion of very low density lipoprotein triacylglycerol
    Lisa Krugner-Higby
    The Research Animal Resources Center, University of Wisconsin Madison, Madison, Wisconsin, USA
    Comp Med 56:468-75. 2006
    California mice (Peromyscus californicus) develop type II diabetes mellitus when fed a high-fat diet...
  100. ncbi Genetic vaccines protect against Sin Nombre hantavirus challenge in the deer mouse (Peromyscus maniculatus)
    Mausumi Bharadwaj
    Center for Emerging Infectious Diseases, Department of Pathology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
    J Gen Virol 83:1745-51. 2002
    We used a deer mouse (Peromyscus maniculatus) infection model to test the protective efficacy of genetic vaccine candidates for Sin Nombre (SN) virus that were known to provoke immunological responses in BALB/c mice (Bharadwaj et al...
  101. pmc Melanism in peromyscus is caused by independent mutations in agouti
    Evan P Kingsley
    Department of Organismic and Evolutionary Biology and The Museum of Comparative Zoology, Harvard University, Cambridge, Massachusetts, United States of America
    PLoS ONE 4:e6435. 2009
    ..or other genes cause melanism in the wild, we investigated the genetic basis of melanism in the rodent genus Peromyscus, in which melanic mice have been reported in several populations...

Research Grants62

  1. Mechanism(s) of Alcoholic Pancreatitis
    Bhupendra S Kaphalia; Fiscal Year: 2011
    ....
  2. Photoperiod Brain and Behavior
    Randy J Nelson; Fiscal Year: 2012
    ..Male Peromyscus mice reduce hippocampal size and spatial memory performance in short days;short days decrease apical CA1 spine ..
  3. Environmental regulation of estrogen dependent aggression
    Brian C Trainor; Fiscal Year: 2013
    ..Recent studies on Peromyscus identified a similar pattern for male behavior...
  4. The evolutionary and molecular mechanisms underlying sperm performance in an emer
    Heidi S Fisher; Fiscal Year: 2013
    ..In contrast, a close relative to the laboratory mouse, deer mice in the genus Peromyscus, exhibit striking differences in reproductive anatomy, sperm production, morphology and motility among species...
  5. Sex Differences in the Roles of Oxytocin and Vasopressin in Social Withdrawal
    Michael Q Steinman; Fiscal Year: 2013
    ..California mouse (Peromyscus californicus) males and females are territorial, making them suitable for studying sex differences...
  6. Metabolic and Energetic Consequences of Fatherhood
    Wendy Saltzman; Fiscal Year: 2013
    ..The proposed studies will characterize the effects of fatherhood in the California mouse (Peromyscus californicus), a monogamous rodent in which fathers invest extensively in their offspring and undergo systematic ..
  7. Mechanisms of Hemoglobin Adaptation to Hypoxia in High-altitude Rodents
    Jay F Storz; Fiscal Year: 2012
    ..associated with adaptive variation in the blood biochemistry and aerobic metabolism of high-altitude deer mice (Peromyscus maniculatus)...
  8. Determinants of Borrelia Diversity and Population Structure
    ELISABETH BAUM; Fiscal Year: 2010
    ..S. A major reservoir for the infection is the mouse Peromyscus leucopus...
  9. PEROMYSCUS LABORATORY MODELS FOR BIOMEDICAL RESEARCH
    Gabor Szalai; Fiscal Year: 2013
    The Peromyscus Genetic Stock Center (PGSC) provides a reliable source of disease free peromyscines, and is unmatched for the variety of Peromyscus species and mutants available...
  10. Genetic basis of sperm competition in Peromyscus
    Heidi S Fisher; Fiscal Year: 2010
    ..In contrast, a close relative to the laboratory mouse, the genus Peromyscus, exhibit striking differences in testes size, ejaculate traits, sperm morphology and swimming performance ..
  11. Babesiosis Emergence in the United States
    MARIA ANA DIUK-WASSER; Fiscal Year: 2013
    ..burgdorferi in the laboratory by employing established colonies of /. scapularis and white-footed mice {Peromyscus leucopus) and will explore how host coinfection with both pathogens enhances B. m/crof/transmission (Aim 1)...
  12. Using genomics to understand physiologic water conservation in desert rodents
    MATTHEW MACMANES; Fiscal Year: 2013
    ..Specifically, I will study this phenomenon using three species of rodents within the genus Peromyscus in Southern California. Of these, 2 (P. eremicus and P. crinitus) are desert adapted while a 3rd (P...
  13. Adaptive Evolutionary Responses of White-footed Mice (Peromyscus leucopus) to Urb
    Jason Munshi-South; Fiscal Year: 2012
    ..will use these new approaches to examine adaptation to urbanization among populations of the white-footed mouse (Peromyscus leucopus), in New York City...
  14. Microencapsulation of oocytes for low-CPA (cryoprotectant) vitrification
    Xiaoming He; Fiscal Year: 2013
    ..Oocytes of the naturally bred (outbred) Peromyscus will be used as the biological model in this project so that the results obtained from the proposed studies can ..
  15. RISK OF TBE IN NORTH AMERICA FOCI OF LYME DISEASE
    Andrew Spielman; Fiscal Year: 1992
    ..dammini, the vector of the Lyme disease spirochete...
  16. Molecular mechanisms underlying parallel Agouti adaptation in Peromyscus
    CATHERINE LINNEN; Fiscal Year: 2009
    ..that a dominant mutation in the Agouti regulatory region is also responsible for light coat color in natural Peromyscus maniculatus (deer mouse) populations inhabiting the Sand Hills region of Nebraska;however, this phenotype ("wide-..
  17. ECOLOGY OF HANTAVIRUS ENZOOTICS: IMMUNE INTERVENTIONS
    Brian Hjelle; Fiscal Year: 2001
    ....
  18. TRANSMISSION OF GRANULOCYTIC EHRLICHIOSIS
    Sam Telford; Fiscal Year: 2000
    ..This agent stably infects intact or splenectomised outbred and inbred mice, as well as Peromyscus leucopus, the main enzootic reservoir of Borrelia burgdorferi and Babesia microti in the northeastern U.S...
  19. Development of Rapid Diagnostic Tests for Hantaviruses
    SERGIO PICHUANTES; Fiscal Year: 2007
    ..abstract_text> ..
  20. MINORITY PREDOCTORAL FELLOWSHIP PROGRAM
    DENISE STEINLEIN; Fiscal Year: 2005
    ..It further tries to develop a Peromyscus mouse infection model for Bartonella washoensis, Bartonella vinsonii subsp arupensis, Bartonella vinsonii subsp ..
  21. ROLE OF TICK SALIVA IN LYME DISEASE AND VACCINE STRATEGY
    Thomas Mather; Fiscal Year: 2006
    ..be screened for their ability to interrupt tick feeding or block pathogen transmission in a white-footed mouse (Peromyscus leucopus) model...
  22. Biodiversity, Habitat Fragmentation, & Lyme Disease Risk
    RICHARD OSTFELD; Fiscal Year: 2006
    ..Our research comprises a rigorous, multidisciplinary approach to understanding the linkages between ecology and risk of infectious disease. ..
  23. ROLE OF TICK SALIVA IN LYME DISEASE AND VACCINE STRATEGY
    Thomas Mather; Fiscal Year: 2001
    ..be screened for their ability to interrupt tick feeding or block pathogen transmission in a white-footed mouse (Peromyscus leucopus) model...
  24. MUTAGENICITY AND FITNESS IMPACTS OF ENVIRONMENTAL TOXINS
    SABINE LOEW; Fiscal Year: 2000
    ..to acute toxicity versus germline mutations, breeding colonies derived from the laboratory-raised F1 generation will be established, and their reproductive success and offspring survival will be monitored (Objective D) ..
  25. Neutralizing Compounds for Viral Hemorrhagic Fever
    Richard Larson; Fiscal Year: 2005
    ....
  26. IMMUNOLOGIC & EPIDEMIOLOGIC STUDIES OF EMERGING VIRUSES
    Michael Buchmeier; Fiscal Year: 1999
    ..Project 3 will investigate why Sin Nombre virus (SNV) has a relatively high rate of endemic infection in Peromyscus spp., but a low incidence of exposure in high risk human populations...
  27. Role of Heat Shock Response in a Zoonotic Virus
    Brian Hjelle; Fiscal Year: 2002
    DESCRIPTION: (provided by the applicant): Deer mice (Peromyscus maniculatus) are the natural reservoirs for Sin Nombre (SN) Hantavirus, the cause of an often-fatal acute cardiorespiratory illness, Hantavirus cardiopulmonary syndrome (HCPS)..
  28. PATHOGENESIS OF DIABETES IN CALIFORNIA MICE
    Lisa Krugner Higby; Fiscal Year: 2000
    ..determinants of disease occurrence and progression that are relevant to the human disease The California mouse (Peromyscus californicus) is a desert rodent closely related to the white-footed deer mouse (Peromyscus leucopus), a ..
  29. Alterations:Mice exposed to N-nitroso metabolites of RDX
    George Cobb; Fiscal Year: 2006
    ..we are testing the hypothesis: Nitroso transformation products of (RDX) will be mutagens in deer mice (peromyscus maniculatus)...
  30. WILDLIFE ORAL VACCINE AGAINST B. BURGDORFERI
    Maria Gomes Solecki; Fiscal Year: 2006
    ..abstract_text> ..
  31. MOLECULAR AND SOMATIC CELL MAPPING OF DEER MOUSE GENES
    DUKE ROGERS; Fiscal Year: 1991
    ..The deer mouse (genus Peromyscus) is considered the ideal model for directed comparative mapping efforts for several reasons...
  32. HISTOCOMPATIBILITY SYSTEMS AND AGING
    Roy Walford; Fiscal Year: 1990
    ..to comparative and interactive work with the common laboratory mouse (the first task being to establish Peromyscus as a "gerontologic" animal)...
  33. Neuroendocrinology of differential female aggression
    Ellen Davis; Fiscal Year: 2002
    ..First, I will demonstrate plasticity in aggression in female Peromyscus californicus and their ability to win encounters both due to previous experience and across reproductive states...
  34. MECHANISM AND FUNCTION OF GENOMIC IMPRINTING
    Shirley Tilghman; Fiscal Year: 2002
    ..Finally the evolution of imprinting will be studied in the marsupial, Monodelphis, and in two strains of the wild mouse Peromyscus, where dramatic perturbations in growth are observed in reciprocal F1 hybrids.
  35. GENETICS, STRUCTURE, AND EXPRESSION OF IA ANTIGENS
    Patricia Jones; Fiscal Year: 1993
    ..II genes of rodent species belonging to subfamilies of the family Muridae distinct from mice and rats, namely Peromyscus, Microtus, and Spalax...
  36. RESERVOIR IMMUNITY IN LYME DISEASE VECTOR COMPETENCE
    Sam Telford; Fiscal Year: 1999
    ..It is anticipated-that these observations on the manner in which a pathogen interacts with its reservoir and vector may provide basic information on the mode of perpetuation of tick-borne microorganisms in nature. ..
  37. Development of Peromyscus Genomics
    Michael Felder; Fiscal Year: 2007
    Peromyscines are the most widely distributed and abundant native North American mammals. Recently Peromyscus leucopus and P maniculatus abruptly rose to national attention when they were discovered to be the primary reservoirs of microbes ..
  38. MAJOR HISTOCOMPATIBILTY COMPLEX--AGING & TRANSGENIC MICE
    Rita Effros; Fiscal Year: 1992
    ..of the MHC to aging by making transgenic Mus with genes cloned from the MHC of the long-lived (7-8 year) rodent Peromyscus leucopus...
  39. ISOLATION AND CHARACTERIZATION OF RODENT LENTIVIRUSES
    Ruth Ruprecht; Fiscal Year: 1992
    ..initially using neonates of inbred laboratory mice (Mus musculus) or clean colonies of other species of Mus of Peromyscus. If no laboratory stains can be infected, pathogen-free stains of wild rodents will be developed. 7...
  40. BENEDICT COLLEGE MBRS/SCORE PROGRAM
    Samir Raychoudhury; Fiscal Year: 2001
    ..Synergistic effects of PCBs and DDE on Reproduction in Peromyscus, Dr. George McCoy, Principle Investigator and Dr. Mary F. Finlay, Co-Principal Investigator. ...
  41. Estrogen receptors, photoperiod, and aggression
    BRIAN TRAINOR; Fiscal Year: 2007
    ..The proposed research should provide a novel and important framework to understand how the environment interacts with ER function to modulate behavior. ..
  42. Aromatase regulation of paternal behavior and aggression
    BRIAN TRAINOR; Fiscal Year: 2002
    ..In summary, this proposal examines how aromatase mediates the effects of testosterone and social behavior. ..
  43. BRAIN METHYLATION AND EPILEPTOGENESIS
    OTTO SELLINGER; Fiscal Year: 1980
    ..comparing the rates of selected methylation reactions in the brain of the wild-type, audiogenic seizure-resistant deermouse, Peromyscus maniculatus, to those prevailing in the brain of its audiogenic seizure-sensitive mutant counterpart.
  44. Liposomal Opioids Extend Analgesia in Laboratory Animals
    Lisa Krugner Higby; Fiscal Year: 2008
    ..If proven efficacious, these analgesic regimens would lead to a significant change in the post-surgical care of animals used in biomedical research and veterinary medicine. ..
  45. BIOLOGY AND CONTROL OF LYME DISEASE BORRELIA
    Alan Barbour; Fiscal Year: 2004
    ..The hypotheses for the project are the following: (A) A high prevalence of anti-OspA antibodies among Peromyscus leucopus and/or other mammalian reservoirs in the field will reduce the transmission rate between reservoir ..
  46. Tolerated xenografts using virus stealth technology
    MARK CREW; Fiscal Year: 2003
    ..Moreover, the proposed exploitation of viral stealth technology could be readily adopted for allotransplants especially those involving allogeneic stem cells. ..
  47. Rapid, accurate diagnostics for arenaviral infections
    CHARLES FULHORST; Fiscal Year: 2003
    ..g., Amapari, Flexal) that were not used to develop or test the first generation assay. ..
  48. Regulation of Circadian Activity Rhythms by Hypocretins
    Eric Mintz; Fiscal Year: 2002
    ..abstract_text> ..
  49. HEALTH BURDERN OF COINFECTING DEER ASSOCIATED ZOONOSES
    Peter Krause; Fiscal Year: 2001
    ..The density of deer will be estimated in each site. This proposed effort will help define the health burden imposed on people residing in proximity to deer and will contribute to diagnosis and case-management of apparent Lyme disease. ..
  50. Animal models of hantavirus cardiopulmonary disease
    CHARLES FULHORST; Fiscal Year: 2006
    ..A mouse model of severe or lethal HCPS could substantively augment studies on the pathogenesis of the capillary leak that results in the life-threatening pulmonary edema HCPS. ..
  51. Perfluorooctane sulfonate (PFOS) Affects Immunity through PPAR-alpha.
    Margie Peden Adams; Fiscal Year: 2007
    ..The unimmunized and immunized experiments will be conducted to control for possible differences in response related to lymphocyte activation from the immunization. [unreadable] [unreadable] [unreadable]..
  52. The Psychobiology of Rhythms in Diurnal Mammals
    Laura Smale; Fiscal Year: 2009
    ..These insights will help us understand and eventually alleviate the myriad medical and behavioral problems faced by shift workers, who represent 16% of Americans ..
  53. Proximal determinants of risk for tularemia outbreaks
    Sam Telford; Fiscal Year: 2004
    ..tularensis in the environment; and, ultimately, a better understanding of F. tularensis-host interactions. ..
  54. Perpetuation of Francisella tularensis
    Sam R Telford; Fiscal Year: 2010
    ..Taken together, these observations will provide a basis for understanding how the agent of tularemia is perpetuated on Martha's Vineyard, and why pneumonic human disease is prevalent there. ..
  55. Viral determinants of hantavirus pulmonary disease in the hamster
    Charles F Fulhorst; Fiscal Year: 2010
    ..The plasmid-based genetic system could be used in future studies to develop vaccines to prevent infection or disease and to (in the face of clinical disease) mitigate the severity of HPS. ..