Genomes and Genes
Summary: A suborder of PRIMATES consisting of six families: CEBIDAE (some New World monkeys), ATELIDAE (some New World monkeys), CERCOPITHECIDAE (Old World monkeys), HYLOBATIDAE (gibbons and siamangs), CALLITRICHIDAE (marmosets and tamarins), and HOMINIDAE (humans and great apes).
Publications242 found, 100 shown here
- Parietal lobe: from action organization to intention understandingLeonardo Fogassi
Dipartimento di Psicologia, Universita di Parma, Borgo Carissimi 10, 43100 Parma, Italy
Science 308:662-7. 2005..Thus, these neurons not only code the observed motor act but also allow the observer to understand the agent's intentions...
- A recurrent network mechanism of time integration in perceptual decisionsKong Fatt Wong
Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts 02454, USA
J Neurosci 26:1314-28. 2006..Our reduced two-variable neural model offers a simple yet biophysically plausible framework for studying perceptual decision making in general...
- Internal models of eye movement in the floccular complex of the monkey cerebellumS G Lisberger
Howard Hughes Medical Institute, Department of Physiology, W M Keck Foundation Center for Integrative Neuroscience, University of California, Box 0444, 513 Parnassus Avenue, Room HSE 802, San Francisco, CA 94143 0444, USA
Neuroscience 162:763-76. 2009..Perhaps the insights from studying oculomotor control provide groundwork to guide the analysis of internal models for a wide variety of cerebellar behaviors...
- Basal anthropoids from Egypt and the antiquity of Africa's higher primate radiationErik R Seiffert
Department of Earth Sciences, University of Oxford, and Oxford University Museum of Natural History, Parks Road, Oxford, OX1 3PW, UK
Science 310:300-4. 2005....
- The cortical motor systemG Rizzolatti
Istituto di Fisiologia Umana, Universita di Parma, Via Volturno 39, I43100 Parma, Italy
Neuron 31:889-901. 2001..We submit that generating internal representations of actions is central to cortical motor function. External contingencies and motivational factors determine then whether these action representations are transformed into actual actions...
- Rotavirus infection activates the UPR but modulates its activityJose Luis Zambrano
Immunology and Infectious Diseases, Montana State University, Bozeman, MT 59718, USA
Virol J 8:359. 2011..We also sought to identify proteins outside the IFN induction and signaling pathway that were modulated by rotavirus infection...
- Evolution of eye size and shape in primatesCallum F Ross
Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637, USA
J Hum Evol 52:294-313. 2007..These data support the conclusion that the origin of anthropoids was associated with a change in eye shape to improve visual acuity in the context of a diurnal predatory habitus...
- Plasmodium knowlesi: a malaria parasite of monkeys and humansWilliam E Collins
Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Annu Rev Entomol 57:107-21. 2012..The parasite was a major monkey animal model for developing antimalarial vaccines and investigations of the biology of parasite invasion. P. knowlesi is the first monkey malaria parasite genome to be sequenced and annotated...
- A role for neural integrators in perceptual decision makingMark E Mazurek
Howard Hughes Medical Institute, Department of Physiology and Biophysics, and National Primate Research Center, University of Washington, Seattle, WA 98195 7290, USA
Cereb Cortex 13:1257-69. 2003..The model explains a variety of behavioral and physiological measurements obtained from monkeys...
- New perspectives on anthropoid originsBlythe A Williams
Department of Evolutionary Anthropology, Duke University, Durham, NC 27708 0383, USA
Proc Natl Acad Sci U S A 107:4797-804. 2010..Progress in comparative anatomy, genomics, and molecular biology point to key changes in sensory ecology and brain organization that ultimately set the stage for the emergence of the human lineage...
- Parieto-frontal coding of reaching: an integrated frameworkY Burnod
INSERM CREARE U 483, UPMC, 9 Quai St Bernard, Paris F 75005, France
Exp Brain Res 129:325-46. 1999..This will result in a progressive match of retinal, gaze, arm, and muscle signals suitable for moving the hand toward the target...
- Gamma-band synchronization in visual cortex predicts speed of change detectionThilo Womelsdorf
FC Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, 6525 EN Nijmegen, The Netherlands
Nature 439:733-6. 2006....
- Parabolic movement primitives and cortical states: merging optimality with geometric invarianceFelix Polyakov
Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, 76100 Rehovot, Israel
Biol Cybern 100:159-84. 2009..We thus suggest that the cortical representation of movements is state-dependent and that parabolic elements are building blocks used by the motor system to generate complex movements...
- From monkeys to humans: what do we now know about brain homologies?Martin I Sereno
Department of Cognitive Sciences, University of California, San Diego, La Jolla, CA 92093 0515, USA
Curr Opin Neurobiol 15:135-44. 2005....
- AIDS as a zoonosis: scientific and public health implicationsB H Hahn
Department of Medicine, Howard Hughes Medical Institute, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Science 287:607-14. 2000..The implications of human infection by a diverse set of SIVs and of exposure to a plethora of additional human immunodeficiency virus-related viruses are discussed...
- Retinopathy in monkeys with spontaneous type 2 diabetesSahng Y Kim
Wilmer Ophthalmological Institute, The Johns Hopkins University School of Medicine, Baltimore, MD 21287 9115, USA
Invest Ophthalmol Vis Sci 45:4543-53. 2004..The purpose of this study was to investigate clinically and histopathologically the ocular changes in these monkeys...
- Multidimensional recording (MDR) and data sharing: an ecological open research and educational platform for neuroscienceYasuo Nagasaka
Laboratory for Adaptive Intelligence, BSI, RIKEN, Saitama, Japan
PLoS ONE 6:e22561. 2011..org. These recording and sharing methods support an ecological system that is open to everyone and will be a valuable and powerful research/educational platform for understanding the dynamic mechanisms of neural networks...
- Feature- and order-based timing representations in the frontal cortexAldo Genovesio
Laboratory of Systems Neuroscience, National Institute of Mental Health, Bethesda, MD 20892, USA
Neuron 63:254-66. 2009..By representing stimulus durations and relative durations--both bound to stimulus features and event order--the frontal cortex could contribute to both temporal perception and episodic memory...
- Spatial memory and the monkey hippocampus: not all space is created equalPamela Banta Lavenex
Laboratory of Brain and Cognitive Development, Department of Medicine, Unit of Physiology, University of Fribourg, FR 1700, Switzerland
Hippocampus 19:8-19. 2009..Finally, we conclude that the available data demonstrate unequivocally that the central role of the hippocampus in allocentric, spatial relational learning and memory is conserved among vertebrates, including nonhuman primates...
- Emergence of a novel and highly divergent HTLV-3 in a primate hunter in CameroonHaoqiang Zheng
Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Virology 401:137-45. 2010....
- Anthropoid primates from the Oligocene of Pakistan (Bugti Hills): data on early anthropoid evolution and biogeographyLaurent Marivaux
Laboratoire de Paléontologie, Institut des Sciences de l Evolution de Montpellier, Unité Mixte de Recherche Centre National de la Recherche Scientifique 5554, c c 064, Universite Montpellier II, Montpellier, France
Proc Natl Acad Sci U S A 102:8436-41. 2005..These fossils provide data on temporal and paleobiogeographic aspects of early anthropoid evolution and significantly expand the record of stem anthropoid evolution in the Paleogene of South Asia...
- The prefrontal cortex: response selection or maintenance within working memory?J B Rowe
Wellcome Department of Cognitive Neurology, Institute of Neurology, 12 Queen Square, London WC1N 3BG, UK
Science 288:1656-60. 2000..This accounts for the fact that this area is activated both when subjects select between items on working memory tasks and when they freely select between movements on tasks of willed action...
- Object representations in the temporal cortex of monkeys and humans as revealed by functional magnetic resonance imagingAndrew H Bell
Laboratory of Brain and Cognition, National Institute of Mental Health, 49 Convent Dr, Bethesda, MD 20892, USA
J Neurophysiol 101:688-700. 2009..In addition, they further support the idea that representations of complex stimuli in IT cortex are organized into multiple hierarchical tiers, encompassing both semantic and physical properties...
- Mapping of the preferred direction in the motor cortexApostolos P Georgopoulos
Brain Sciences Center, Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
Proc Natl Acad Sci U S A 104:11068-72. 2007..These findings provide evidence for an orderly mapping of the preferred direction in the motor cortex...
- Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator proteinJ I Huggenvik
Department of Physiology, Southern Illinois University School of Medicine, Carbondale 62901 6523, USA
Mol Endocrinol 12:1619-39. 1998..The sequence and functional similarities between NUDR and DEAF-1 suggest that NUDR may also act as a cofactor to regulate the transcription of genes during fetal development or differentiation of testicular cells...
- Decision-making with multiple alternativesAnne K Churchland
Howard Hughes Medical Institute, Department of Physiology and Biophysics, National Primate Research Center, University of Washington Medical School, Seattle, Washington 98195, USA
Nat Neurosci 11:693-702. 2008..These physiological observations constitute an effective strategy for handling increased task difficulty. The differences appear to explain subjects' accuracy and reaction times...
- Progress and prospects: naked DNA gene transfer and therapyH Herweijer
Mirus Corporation and University of Wisconsin Madison, Madison, WI 53705, USA
Gene Ther 10:453-8. 2003..The availability of plasmid DNA expression vectors that enable sustained high level expression, allows for the development of gene therapies based on the delivery of naked plasmid DNA...
- Retrospective and prospective persistent activity induced by Hebbian learning in a recurrent cortical networkGianluigi Mongillo
Dipartimento di Fisiologia Umana, Universita di Roma La Sapienza, Rome, Italy INFM, Dipartimento di Fisica, Universita di Roma La Sapienza, Rome, Italy
Eur J Neurosci 18:2011-24. 2003....
- Natural products that reduce rotavirus infectivity identified by a cell-based moderate-throughput screening assayMark E Shaneyfelt
Veterinary Molecular Biology, Montana State University, Bozeman, MT 59715, USA
Virol J 3:68. 2006....
- Late middle Eocene epoch of Libya yields earliest known radiation of African anthropoidsJean Jacques Jaeger
Institut International de Paléoprimatologie et Paléontologie humaine, Évolution et Paléoenvironnements, CNRS UMR 6046, Universite de Poitiers, 40 Avenue du Recteur Pineau, 86022 Poitiers, France
Nature 467:1095-8. 2010....
- Valuation of uncertain and delayed rewards in primate prefrontal cortexSoyoun Kim
Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06510, USA
Neural Netw 22:294-304. 2009..These results show that the primate lateral prefrontal cortex plays a central role in estimating the values of alternative actions based on multiple sources of information...
- PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23Zubair M Ahmed
Section of Human Genetics, Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD, USA
Hum Mol Genet 12:3215-23. 2003..Our results further strengthen the importance of protocadherin 15 in the morphogenesis and cohesion of stereocilia bundles and retinal photoreceptor cell maintenance or function...
- Plasmodium cynomolgi genome sequences provide insight into Plasmodium vivax and the monkey malaria cladeShin Ichiro Tachibana
Laboratory of Malariology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan
Nat Genet 44:1051-5. 2012..The sequencing of the P. cynomolgi genome is a critical step in developing a model system for P. vivax research and in counteracting the neglect of P. vivax...
- Modulation of multidrug resistance protein (MRP1/ABCC1) expression: a novel physiological role for ouabainR C Valente
Instituto de Bioquimica Medica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Cell Biol Toxicol 23:421-7. 2007....
- Rearrangement of receptive field topography after intracortical and peripheral stimulation: the role of plasticity in inhibitory pathwaysGeorge J Kalarickal
Department of Computer Science, University of North Carolina at Chapel Hill, USA
Network 13:1-40. 2002..It is shown that lateral inhibitory pathway plasticity is sufficient to model RF changes and increase in position discrimination after peripheral stimulation. Several novel and testable predictions are made based on the EXIN model...
- Language evolution: semantic combinations in primate callsKate Arnold
School of Psychology, University of St Andrews, St Andrews KY16 9JP, UK
Nature 441:303. 2006..Our findings indicate that non-human primates can combine calls into higher-order sequences that have a particular meaning...
- Campbell's monkeys concatenate vocalizations into context-specific call sequencesKarim Ouattara
Laboratoire EthoS Ethologie Animale et Humaine, Unite Mixte de Recherche 6552, Centre National de la Recherche Scientifique, Universite de Rennes 1, Station Biologique, 35380 Paimpont, France
Proc Natl Acad Sci U S A 106:22026-31. 2009..As the different sequences were so tightly linked to specific external events, the Campbell's monkey call system may be the most complex example of 'proto-syntax' in animal communication known to date...
- Utilization of the Denny-Brown collection: differential recovery of forelimb and hind limb stepping after extensive unilateral cerebral lesionsJ A Vilensky
Department of Anatomy, Indiana University School of Medicine, Fort Wayne 46805, USA
Behav Brain Res 82:223-33. 1997..This suggests that there is an underlying physiological basis to the widely-held belief that, in humans, lower limb recovery after stroke is generally more complete than that of the upper limb...
- Does skeletal anatomy reflect adaptation to locomotor patterns? Cortical and trabecular architecture in human and nonhuman anthropoidsColin N Shaw
Department of Anthropology, The Pennsylvania State University, University Park, PA 16802, USA
Am J Phys Anthropol 147:187-200. 2012....
- Relating neuronal firing patterns to functional differentiation of cerebral cortexShigeru Shinomoto
Graduate School of Science, Kyoto University, Sakyo ku, Kyoto, Japan
PLoS Comput Biol 5:e1000433. 2009..Thus, signaling patterns may play an important role in function-specific cerebral cortical computation...
- Involvement of the prefrontal cortex in problem solvingHajime Mushiake
Department of Physiology, Tohoku University School of Medicine, 2 1 Seiryo cho, Aoba ku, Sendai 980 8575, Japan
Int Rev Neurobiol 85:1-11. 2009..Our data suggest that the PFC is involved primarily in the dynamic representation of multiple future events that occur as a consequence of behavioral actions in problem-solving situations...
- Measurement of variability dynamics in cortical spike trainsMartin P Nawrot
Bernstein Center for Computational Neuroscience Freiburg, Germany
J Neurosci Methods 169:374-90. 2008..Finally, we discuss the effect of several additional factors such as serial interval correlation and refractory period on the empiric relation of FF and CV(2)...
- SINE insertions in cladistic analyses and the phylogenetic affiliations of Tarsius bancanus to other primatesJ Schmitz
Primate Genetics, German Primate Center, Kellnerweg 4, D 37077 Gottingen, Germany
Genetics 157:777-84. 2001..The three Alu insertions characterized underpin the monophyly of haplorhine primates (Anthropoidea and Tarsioidea) from a novel perspective...
- Comparative mapping of higher visual areas in monkeys and humansGuy A Orban
Lab Neuro en Psychofysiologie, K U Leuven, Medical School, Campus Gasthuisberg, Herestraat 49, B 3000 Leuven, Belgium
Trends Cogn Sci 8:315-24. 2004..In the long term, fMRI offers opportunities to compare the functional anatomy of a variety of cognitive functions in the two species...
- Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificityJoseph E Rabinowitz
Gene Therapy Center Laboratoire de Thérapie Génique, CHU Hotel Dieu, 44035 Nantes Cedex 01, France
J Virol 76:791-801. 2002..The development of these helper plasmids should facilitate direct comparisons of serotypes, as well as begin the standardization of production for further clinical development...
- Synaptic computation underlying probabilistic inferenceAlireza Soltani
Department of Neurobiology and Kavli Institute of Neuroscience, Yale University School of Medicine, New Haven, Connecticut, USA
Nat Neurosci 13:112-9. 2010....
- Independent and redundant information in nearby cortical neuronsD S Reich
Laboratory of Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Science 294:2566-8. 2001..Redundancy was independent of cluster size. Summing neuronal responses to reduce variability discards potentially useful information, and the discarded information increases with cluster size...
- Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor functionErwan Bezard
Basal Gang, Laboratoire de Neurophysiologie, CNRS UMR 5543, Universite Victor Segalen, 33076 Bordeaux, France
Nat Med 9:762-7. 2003....
- Bionomics of Anopheles latens in Kapit, Sarawak, Malaysian Borneo in relation to the transmission of zoonotic simian malaria parasite Plasmodium knowlesiCheong H Tan
Infectious Diseases Research Centre, Institute for Medical Research Jalan Pahang, 50588 Kuala Lumpur, Malaysia
Malar J 7:52. 2008..A study was initiated to identify the vectors of malaria, to elucidate where transmission is taking place and to understand the bionomics of the vectors in Kapit...
- Systemic cancer therapy with a tumor-selective vaccinia virus mutant lacking thymidine kinase and vaccinia growth factor genesJ A McCart
Surgery Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892-1502, USA
Cancer Res 61:8751-7. 2001..It is a promising vector for use in tumor-directed gene therapy, given its enhanced safety profile, tumor selectivity, and the oncolytic effects after systemic delivery...
- A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restrictionMelvyn W Yap
Division of Virology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, United Kingdom
Curr Biol 15:73-8. 2005..A single amino acid substitution (R332P) in the human Trim5alpha can confer the ability to restrict HIV-1, suggesting that small changes during evolution may have profound effects on our susceptibility to cross-species infection...
- Discovery of novel human and animal cells infected by the severe acute respiratory syndrome coronavirus by replication-specific multiplex reverse transcription-PCRLaura Gillim-Ross
Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208, USA
J Clin Microbiol 42:3196-206. 2004..Our data and other in vivo studies indicate that SARS-CoV has a wide host range, suggesting that the cellular receptor(s) utilized by SARS-CoV is highly conserved and is expressed by a variety of tissues...
- Target selection in area V4 during a multidimensional visual search taskTadashi Ogawa
Division of Sensory and Cognitive Information, National Institute for Physiological Sciences, Okazaki, Aichi 444 8585, Japan
J Neurosci 24:6371-82. 2004....
- Neuroscience. Predicting future rewardsBarry J Richmond
Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, MD 20892, USA
Science 301:179-80. 2003
- Linear vestibular self-motion signals in monkey medial superior temporal areaF Bremmer
Department of Zoology and Neurobiology, Ruhr University Bochum, Germany
Ann N Y Acad Sci 871:272-81. 1999..The remaining 25% (5/20) preferred directions that were antialigned. Our results provide strong evidence that neurons in the MST area are at least in part involved in the processing of self-motion...
- Endocytosis by random initiation and stabilization of clathrin-coated pitsMarcelo Ehrlich
Department of Cell Biology, Harvard Medical School and the CBR Institute for Biomedical Research, 200 Longwood Avenue, Boston, MA 02115, USA
Cell 118:591-605. 2004..Cargo incorporation occurs primarily or exclusively in a newly formed coated pit. Our data lead to a model in which coated pits initiate randomly but collapse unless stabilized, perhaps by cargo capture...
- Structure and function of declarative and nondeclarative memory systemsL R Squire
Veterans Affairs Medical Center, San Diego, La Jolla, CA 92161, USA
Proc Natl Acad Sci U S A 93:13515-22. 1996....
- Neural mechanism for stochastic behaviour during a competitive gameAlireza Soltani
Department of Physics and Volen Center for Complex Systems, Brandeis University, Waltham, MA 02454, USA
Neural Netw 19:1075-90. 2006..Finally, when combined with a meta-learning algorithm, our model accounts for the slow drift in the animal's strategy based on a process of reward maximization...
- A neural circuit model of flexible sensorimotor mapping: learning and forgetting on multiple timescalesStefano Fusi
Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Neuron 54:319-33. 2007..This model prediction is confirmed by monkey data. Therefore, our work reveals a scenario for conditional associative learning that is distinct from instant switching between sets of well-established sensorimotor associations...
- Impact of learning on representation of parts and wholes in monkey inferotemporal cortexChris I Baker
Center for the Neural Basis of Cognition, 115 Mellon Institute, 4400 Fifth Avenue, Pittsburgh, Pennsylvania 15213, USA
Nat Neurosci 5:1210-6. 2002..These results indicate a possible neural mechanism for holistic or configural effects in expert versus novice observers...
- The role of cortical area MST in a model of combined smooth eye-head pursuitP W Dicke
Department of Neurology, University of Tubingen, Germany
Biol Cybern 80:71-84. 1999..Since only isodirectional hidden units contributed to the flow of information, the preponderance of isodirectional MSTl-VT neurons might be the result of developmental pruning, eliminating the second group...
- Neuronal correlates of perceptual stability during eye movementsPeter W Dicke
Center for Neurology, Hertie Institute for Clinical Brain Research, Department of Cognitive Neurology, University of Tuebingen, Otfried Mueller Str 27, 72076 Tuebingen, Germany
Eur J Neurosci 27:991-1002. 2008....
- Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shedVincent H J Leonard
Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, USA
J Clin Invest 118:2448-58. 2008..Thus, EpR is probably a basolateral protein, and infection of the airway epithelium is not essential for systemic spread and virulence of MV...
- Detecting precise firing sequences in experimental dataM Abeles
Department of Physiology and Interdisciplinary Center for Neural Computation, The Hebrew University, PO Box 12272, 91 120, Jerusalem, Israel
J Neurosci Methods 107:141-54. 2001..Pitfalls which may cause false detection of PFSs, or loss of existing PFSs, include searching for PFSs in which the same neuron participates more than once, and attempting to produce a surrogate with some fixed statistical property...
- In vitro antiplasmodial activity and cytotoxicity of crude extracts and compounds from the stem bark of Kigelia africana (Lam.) Benth (Bignoniaceae)Denis Zofou
Biotechnology Unit, University of Buea, P O Box 63 Buea, South West Region, Cameroon
Parasitol Res 108:1383-90. 2011..These findings justify the use of K. africana stem bark as antimalaria by traditional healers of Western Cameroon, and could constitute a good basis for further studies towards development of new leads or natural drugs for malaria...
- Comparison of local measures of spike time irregularity and relating variability to firing rate in motor cortical neuronsAdrián Ponce-Alvarez
Institut de Neurosciences Cognitives de la Mediterranee, CNRS Université de la Méditerranée, Marseille, France
J Comput Neurosci 29:351-65. 2010..Neurons with a CV(2)-rate decoupling have a rather constant CV(2) and discharge mainly irregularly. Neurons with a CV(2)-rate coupling can modulate their CV(2) and explore a larger range of CV(2) values...
- Risk to human health from a plethora of simian immunodeficiency viruses in primate bushmeatMartine Peeters
Institue de Recherche pour la Développement, Laboratoire Retrovirus, 911 Avenue Agropolis, BP 5045, 34032 Montpellier Cedex 1, France
Emerg Infect Dis 8:451-7. 2002..These data document for the first time that a substantial proportion of wild monkeys in Cameroon are SIV infected and that humans who hunt and handle bushmeat are exposed to a plethora of genetically highly divergent viruses...
- Differences in spiking patterns among cortical neuronsShigeru Shinomoto
Department of Physics, Graduate School of Science, Kyoto University, Kyoto 606 8502, Japan
Neural Comput 15:2823-42. 2003..This suggests that neurons in each area can be classified into different groups possessing unique spiking statistics and corresponding functional properties...
- Simian T-cell leukemia virus (STLV) infection in wild primate populations in Cameroon: evidence for dual STLV type 1 and type 3 infection in agile mangabeys (Cercocebus agilis)Valerie Courgnaud
UR36, IRD, and University of Montpellier I, Montpellier, France
J Virol 78:4700-9. 2004....
- Unitary events in multiple single-neuron spiking activity: II. Nonstationary dataSonja Grün
Department of Neurophysiology, Max Planck Institute for Brain Research, D 60528 Frankfurt Main, Germany
Neural Comput 14:81-119. 2002..The potential of the new method is illustrated by results from multiple single-unit recordings from frontal and motor cortical areas in awake, behaving monkey...
- Identification and molecular characterization of new STLV-1 and STLV-3 strains in wild-caught nonhuman primates in CameroonFlorian Liegeois
UMR 145, Institut de Recherche pour le Developpement IRD and University of Montpellier 1, Montpellier, France
Virology 371:405-17. 2008..cephus. Finally, we identify relative divergence levels in the tax/rex phylogeny suggesting that additional types of PTLV should be defined, particularly for the highly divergent STLV-1(MarB43) strain that we provisionally name STLV-5...
- New multiple antigenic peptide-based enzyme immunoassay for detection of simian immunodeficiency virus infection in nonhuman primates and humansC B Ndongmo
Division of AIDS, STD, and TB Laboratory, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Clin Microbiol 42:5161-9. 2004..As shown with SIV-infected talapoin monkeys, this assay has the potential to detect previously unidentified SIV strains and should be suitable for sentinel surveillance for potential new cross-species transmissions of SIVs to humans...
- Variability in neuronal activity in primate cortex during working memory tasksM Shafi
Neuropsychiatric Institute, 760 Westwood Plaza, School of Medicine, University of California, Los Angeles, CA 90095 1759, USA
Neuroscience 146:1082-108. 2007..These results may serve as a guide in the evaluation of current theories of the cortical mechanisms of working memory...
- Big bang in the evolution of extant malaria parasitesToshiyuki Hayakawa
Laboratory of Malariology, International Research Center of Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
Mol Biol Evol 25:2233-9. 2008..Interestingly, the rapid diversification coincides with the radiation of the mammalian genera, suggesting that adaptive radiation to new mammalian hosts triggered the rapid diversification of extant malaria parasite lineages...
- Decoding spike trains instant by instant using order statistics and the mixture-of-Poissons modelMatthew C Wiener
Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 4415, USA
J Neurosci 23:2394-406. 2003..Most of the error in estimating stimulus probabilities is attributable to not having enough data to specify the parameters of the model rather than to misspecification of the model itself...
- Central African hunters exposed to simian immunodeficiency virusMarcia L Kalish
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 11:1928-30. 2005..001). One person had strong humoral and weak cellular immune reactivity to SIVcol peptides. Humans are exposed to and possibly infected with SIV, which has major public health implications...
- Touch and go: decision-making mechanisms in somatosensationR Romo
Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, 04510 Mexico, D F Mexico
Annu Rev Neurosci 24:107-37. 2001..Responses recorded in motor areas seem to reflect the output of decision-making operations, which suggests that the ability to make decisions occurs at the sensory-motor interface...
- Genotyping of Giardia intestinalis from domestic and wild animals in Japan using glutamete dehydrogenase gene sequencingTadashi Itagaki
Laboratory of Veterinary Parasitology, Faculty of Agriculture, Iwate University, 3 18 8 Ueda, Morioka 020 0105, Japan
Vet Parasitol 133:283-7. 2005..This is the first report on the genotypes of Giardia isolates from cats, calves and wild monkeys in Japan...
- Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's diseaseChuan En Wang
Department of Human Genetics, Emory University School ofMedicine, Atlanta, GA 30322, USA
Hum Mol Genet 17:2738-51. 2008....
- A triple mutation in the second transmembrane domain of mouse dopamine transporter markedly decreases sensitivity to cocaine and methylphenidateRong Chen
Department of Pharmacology, The Ohio State University College of Medicine, Columbus, Ohio, USA
J Neurochem 94:352-9. 2005..Such functional but cocaine-insensitive DAT mutants can be used to generate a knock-in mouse line to study the role of DAT in cocaine addiction...
- Problem of dural scarring in recording from awake, behaving monkeys: a solution using 5-fluorouracilR L Spinks
Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, United Kingdom
J Neurophysiol 90:1324-32. 2003..It is also possible that this technique may be useful in other situations where there is dural scarring after surgical intervention or injury...
- Association of clathrin, AP-2 adaptor and actin cytoskeleton with developing interlocking membrane domains of lens fibre cellsCheng Jing Zhou
Department of Anatomy and Neurobiology, Morehouse School of Medicine, Atlanta, GA 30310, USA
Exp Eye Res 77:423-32. 2003..The coordinated 'pulling and pushing' actions generated by the clathrin/AP-2 complex and branching actin networks during interlocking domain formation are discussed...
- Shotgun proteomic analysis of Chlamydia trachomatisPaul Skipp
Centre for Proteomic Research, and School of Biological Sciences, University of Southampton, Southampton, UK
Proteomics 5:1558-73. 2005..Taken together, >/=35% of the predicted proteome for C. trachomatis has been experimentally verified, representing the most extensive survey of any chlamydial proteome to date...
- Segmental duplications and the evolution of the primate genomeRhea Vallente Samonte
Department of Genetics and Center for Human Genetics, School of Medicine and University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106, USA
Nat Rev Genet 3:65-72. 2002..Although the precise fraction is unknown, some of these duplicated segments have recently been shown to be associated with rapid gene innovation and chromosomal rearrangement in the genomes of man and the great apes...
- Dengue virus type 2 infections of Aedes aegypti are modulated by the mosquito's RNA interference pathwayIrma Sanchez-Vargas
Department of Microbiology, Arthropod Borne and Infectious Diseases Laboratory, Colorado State University, Fort Collins, Colorado, United States of America
PLoS Pathog 5:e1000299. 2009..Our findings indicate a major role for RNAi as a determinant of DENV transmission by Ae. aegypti...
- Turning on and off with excitation: the role of spike-timing asynchrony and synchrony in sustained neural activityB S Gutkin
Unite de Neurosciences Intergratives et Computationelles, CNRS, Gif-sur-Yvette 91198, France
J Comput Neurosci 11:121-34. 2001..The activity that codes working memories may be structured so that the motor command is both the read-out and a direct clearing signal. We show examples of data that is compatible with our theory...
- The neural origins and implications of imitation, mirror neurons and tool useAtsushi Iriki
RIKEN Brain Science Institute, Laboratory for Symbolic Cognitive Development, 2 1 Hirosawa, Wako Shi, Saitama 351 0198, Japan
Curr Opin Neurobiol 16:660-7. 2006..Although tool-use training is patently non-naturalistic, its marked effects on brain organization and behavior could shed light on the evolution of higher intelligence in humans...
- Optimal decoding of correlated neural population responses in the primate visual cortexYuzhi Chen
Department of Psychology and Center for Perceptual Systems, 1 University Station, A8000, University of Texas at Austin, Austin, Texas 78712, USA
Nat Neurosci 9:1412-20. 2006..Overall, our results suggest an unexpected role for inhibitory mechanisms in efficient decoding of neural population responses...
- Sensory-motor and cognitive functions of the human posterior parietal cortex involved in manual actionsSarah H Creem-Regehr
Department of Psychology, University of Utah, Salt Lake City, UT 84112, USA
Neurobiol Learn Mem 91:166-71. 2009..Proposed theories of multiple dorsal stream systems supporting different action-relevant goals are discussed...
- Dynamics of depolarization and hyperpolarization in the frontal cortex and saccade goalEyal Seidemann
Department of Neurobiology and the Grodetsky Center for Studies of Higher Brain Function, Weizmann Institute of Science, Rehovot 76100, Israel
Science 295:862-5. 2002..During this hyperpolarization saccades are almost exclusively ipsilateral, suggesting an important role for hyperpolarization in determining saccade goal...
- Loss of N-glycolylneuraminic acid in human evolution. Implications for sialic acid recognition by siglecsE C Brinkman-Van der Linden
Glycobiology Research and Training Center and Department of Medicine, University of California San Diego, La Jolla, California 92093, USA
J Biol Chem 275:8633-40. 2000..Others showed that siglec-4a (myelin-associated glycoprotein) prefers Neu5Ac over Neu5Gc. Thus, the human loss of Neu5Gc may alter biological processes involving siglec-1, and possibly, siglec-4a or -5...
- Identification of a highly divergent HIV type 2 and proposal for a change in HIV type 2 classificationFlorence Damond
Virology Department, Hopital Bichat, 75877 Paris 18, France
AIDS Res Hum Retroviruses 20:666-72. 2004..The single-strain lineages C to G and the 96FR12034 lineage identified here should be considered only as putative groups until related strains are identified that confirm circulation of these viruses in the human population...
- Task-related modulation in the monkey inferotemporal cortexGyula Sary
Department of Physiology, University of Szeged, H 6720, Dom ter 10, Szeged, Hungary
Brain Res 1121:76-82. 2006..It was found that behavioral relevance reduces the latency in the inferotemporal cortex and it was concluded that behavioral significance accelerates information processing. This effect has not been described previously...
- Neurons of the cerebral cortex exhibit precise interspike timing in correspondence to behaviorTomer Shmiel
Bar Ilan University, Ramat Gan 52900, Israel
Proc Natl Acad Sci U S A 102:18655-7. 2005..Here we show, in behaving monkeys, that time intervals between spikes, measured in correspondence to a specific behavior, may be controlled to within the milliseconds range...
- Metabolism of the new nonbenzodiazepine anxiolytic agent, RWJ-51204, in mouse, rat, dog, monkey and human hepatic S9 fractions, and in rats, dogs and humansW N Wu
Johnson and Johnson Pharmaceutical Research and Development, LLC, Spring House, PA 19477, USA
Eur J Drug Metab Pharmacokinet 29:263-8. 2004..Pathways 2-4 formed minor/trace oxidized, and dehydrated metabolites. RWJ-51204 is extensively metabolized in vitro (except dog) and in vivo in rats, dogs and humans...
- Interspecies scaling of biliary excreted drugs: a comparison of several methodsIftekhar Mahmood
Clinical Pharmacology and Toxicology Branch HFD 579, Office of Drug Evaluation VI, Center for Drug Evaluation and Research, Food and Drug Administration, Woodmont Office Center II, Rockville, Maryland 20852, USA
J Pharm Sci 94:883-92. 2005..The simple allometry and the monkey liver blood flow (MLBF) approaches gave almost similar results. For some drugs the simple allometry predicted clearance better than the MLBF approach and vice versa...
- Enantiomer ratio of MK-0767 in humans and nonclinical speciesZhongzhou Shen
Department of Drug Metabolism, Merck Research Laboratories, Rahway, NJ 07065, USA
Rapid Commun Mass Spectrom 19:1125-9. 2005....
- A mathematical description of the functionality of correction factors used in allometry for predicting human drug clearanceHuadong Tang
Department of Pharmaceutical Sciences, College of Pharmacy, The University of Arizona, Tucson, AZ 85721, USA
Drug Metab Dispos 33:1294-6. 2005..However, ROE may still serve as a useful practical approach in predicting human CL since it was derived from real observations and has been applied to many examples...
- GB toxicity reassessed using newer techniques for estimation of human toxicity from animal inhalation toxicity data: new method for estimating acute human toxicity (GB)R W Bide
Defence R and D Canada Suffield, Box 4000, Medicine Hat, Alberta, Canada T1A 8K6
J Appl Toxicol 25:393-409. 2005..These values are recommended for general use for the total human population. The empirical relationships employed in the calculations may not be valid for exposure times >30 min...
- Accuracy of allometrically predicted pharmacokinetic parameters in humans: role of species selectionHuadong Tang
Department of Pharmaceutical Sciences, College of Pharmacy, The University of Arizona, Tucson, AZ 85721, USA
Drug Metab Dispos 33:1288-93. 2005..Appreciation of this species or weight dependence should guide researchers in selecting animal species and designing optimal experiments in the application of allometric scaling...
- Characterization of the Bex gene family in humans, mice, and ratsEnrique Alvarez
Medical Scientist Training Program, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Gene 357:18-28. 2005..We conclude that the Bex gene family members are highly homologous but differ in their expression patterns, subcellular localization, and degradation by the proteasome...
- DEVELOPMENT OF THE CORTICOTHALAMIC SYSTEMEdward Jones; Fiscal Year: 2003..Defective maturation may be a concomitant of or a basis for certain forms of seizures in young individuals. ..
- CORTICAL ACTIVITY DURING INDIVIDUATED MOVEMENTMarc Schieber; Fiscal Year: 2002..Finally, we will map M1 repeatedly during motor skill learning to determine (Aim 4) whether any spatial segregation diminishes as the M1 territories that provide output to trained muscles progressively enlarge and increasingly overlap. ..
- NEURONAL POPULATIONS PARTICIPATING IN MOTORIC CHOICESMarc Schieber; Fiscal Year: 2004..inactivation or microstimulation of the PMv, SMA, and striatum bias motoric choices? (4) How do the partially overlapping cortico-striatal projections from the PMv and SMA correlate with striatal regions participating in motoric choices? ..
- ACTIVITY-DEPENDENT PLASTICITY IN SENSORY CORTEXEdward Jones; Fiscal Year: 2004....
- Randomized Controlled Trial of Pediatric CI TherapyEdward Taub; Fiscal Year: 2006..abstract_text> ..
- Visual Target Selection for Saccadic Eye MovementsMichele Basso; Fiscal Year: 2007..abstract_text> ..
- A TREATMENT FOR EXCESS MOTOR DISABILITY IN THE AGEDEdward Taub; Fiscal Year: 2007..abstract_text> ..
- Complete Proteome of Cerebrospinal FluidSteven Schutzer; Fiscal Year: 2006..unreadable] [unreadable] [unreadable] [unreadable]..
- Object-Centered Eye-Movement Signals in the CortexCarl Olson; Fiscal Year: 2004..Series 4 will investigate whether neurons in the frontal eve field (FEF) carry object-centered signals. ..
- ASSAY TO DETECT ACUTE ACTIVE LYME DISEASESteven Schutzer; Fiscal Year: 2005..It can also detect infection early than free antibody assays. Therefore this assay can fulfill a great need in Lyme disease diagnosis and has high market potential. ..
- Development & Manufacture of an MDR Tuberculosis VaccineSteven Reed; Fiscal Year: 2005..This will enable us to immediately proceed to human clinical trials after the end of the funding period. ..
- Neural circuitry of the parietal lobeRALPH SIEGEL; Fiscal Year: 2006....
- Detection of Virulent Burkholderia malleiSteven Schutzer; Fiscal Year: 2006..In Phase 2 we will also develop the immuno-based assays. ..
- Framework for Modeling Human CognitionCarl Olson; Fiscal Year: 2006....
- SYNAPTIC CONNECTIONS OF SPINAL CORD NEURONSWilliam Willis; Fiscal Year: 2007..Preliminary evidence supports the feasibility of the work and suggests that the results could lead to a number of new targets for improvements in pain therapy. ..
- SPATIAL FUNCTIONS OF THE MEDIAL TEMPORAL LOBEWENDY SUZUKI; Fiscal Year: 2008..The results from these studies have implications for understanding a variety of neurological states associated with memory dysfunction including Alzheimer's disease, epilepsy and schizophrenia. ..
- CRCNS - Higher-Level Neural Specialization for Natural Shape StatisticsCHARLES CONNOR; Fiscal Year: 2008..abstract_text> ..
- Human T Cell Antigens of Mycobacterium tuberculosisSteven Reed; Fiscal Year: 2009..Finally, we will test antigens/vaccine formulations in rodent models of infection and disease. By the end of the funding period, we will have defined a second vaccine candidate for entry into clinical trials. ..
- ANALYSIS OF STRUCTURE-FROM-MOTION IN VISUAL CORTEXRALPH SIEGEL; Fiscal Year: 2003..These studies will be crucial in correctly choosing which parietal representations are best modified through therapy when there are spatial deficits in human subjects caused by parietal damage through stroke. ..
- NEURAL EFFECTS OF INTERFERENCE WITH WORKING MEMORYClayton Curtis; Fiscal Year: 2002..abstract_text> ..
- Assay to detect early neurologic Lyme diseaseSteven Schutzer; Fiscal Year: 2003..BbIC Ab and Ag will be identified. Focus will be towards on specific and in vivo expressed Bb Ags. Results will be statistically analyzed. Phase 2 will be designed for broadscale usage and refinement. ..
- LIVE, ATTENUATED, RECOMBINANT VACCINE - WEST NILE VIRUSThomas Monath; Fiscal Year: 2002..abstract_text> ..
- Racial Variations in Optic Nerve Head Structure and BiomechanicsJ CRAWFORD contact DOWNS; Fiscal Year: 2011....
- The Cortical Representation of Oculomotor ProprioceptionMichael Goldberg; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- NEUROBIOLOGICAL PARAMETERS OF COCAINE REINFORCEMENTScott Hemby; Fiscal Year: 2008..abstract_text> ..
- Functional Imaging of Decision NetworksVINCENT FERRERA; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Toward a Unified Model of Cognitive ControlRANDALL O REILLY; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
- OLFACTORY CORTEXJoseph Price; Fiscal Year: 2002..By correlating the PET and MRI images, levels of metabolic and synaptic activity can be determined within the defined architectonic areas as a function of unipolar or bipolar depression. ..
- Chemoprevention Through Activation of Estrogen Receptor Alpha-Induced SenescenceHarikrishna Nakshatri; Fiscal Year: 2007..Our long- term goal is to identify molecular targets for senescence-based chemoprevention strategies for ERa-positive breast cancers. [unreadable] [unreadable] [unreadable]..
- Novel Brain Neuroimaging Markers of Age-Related Mobility ImpairmentCaterina Rosano; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- NEURAL CONTROL OF VERGENCE AND OCULAR ACCOMMODATIONPAUL GAMLIN; Fiscal Year: 2001....
- Molecular and Structural Bases of Hypothalamic PubertyTONY PLANT; Fiscal Year: 2009....
- Visual and Auditory Processing Streams in the Cerebral CortexJosef P Rauschecker; Fiscal Year: 2010..abstract_text> ..
- Induction of HIV-specific Immune ResponsesRajesh T Gandhi; Fiscal Year: 2010..By understanding the mechanisms by which immune responses against HIV can be augmented, this may lead to improved ways of treating this disease and may help in developing a vaccine to prevent this infection. ..
- rTMS and Motor Learning Training to Promote Recovery from HemiparesisJames Carey; Fiscal Year: 2009..The potential impact of this research is a radical change to rehabilitation that accomplishes a higher quality of life in stroke. ..
- Modulation of HIV-1 specific T cell function by TLR ligandsMarcus Altfeld; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- 3D Reconstruction of Optic Nerve HeadsJ Downs; Fiscal Year: 2008..Using these 3D reconstructions of the ONH and principles of biomechanical engineering, we can model the mechanical and vascular effects of elevated IOP in glaucoma. [unreadable] [unreadable] [unreadable]..
- METHYLATION PROFILING AND RISK OF COLORECTAL CANCERHassan Ashktorab; Fiscal Year: 2007..These studies will help in the detection and _rofiling of genetic changes in the pathway of CRC in AA. ..
- MODELING THE MENOPAUSAL TRANSITION AND MENOPAUSEJAY KAPLAN; Fiscal Year: 2008..Therefore the proposed program is directly relevant to the missions of multiple NIHInstitutes, including - butnot limited to - NIA, NICHD, NHLBI, NIDDKand NIMH. ..
- LIGAND GATED ION CHANNELS AND ETOH DISCRIMINATIONKathleen Grant; Fiscal Year: 2001..These findings will suggest variables that determine the effectiveness of pharmacological agents to block ethanol's stimulus effects, and may suggest the appropriate receptor system(s) to target. ..
- MULTIDIMENSIONAL DYNAMIC OF THE VESTIBULO OCULAR REFLEXTheodore Raphan; Fiscal Year: 2008..When the study is completed, we will have a quantitative model of how the vestibular system contributes to maintenance of binocular gaze stability while moving. ..
- Fast and slow dopamine signaling in prefrontal cortexJeremy Seamans; Fiscal Year: 2006..A new theory will be proposed that incorporates fast and slow signaling from VTA neurons and that explains the existing literature while providing a new way to think about normal and pathological states involving PFC DA. ..
- Molecular Fingerprint of Cocaine Abuse AnalysisScott Hemby; Fiscal Year: 2003..In addition, identification of differentially expressed genes may provide novel targets for the pharmacotherapeutic development and/or the refinement of existent pharmacotherapies. ..
- A Computational Facility for Neuroimaging ResearchGregory McCarthy; Fiscal Year: 2003..abstract_text> ..
- COOPERATIVE HUMORAL & CELLULAR IMMUNITY AGAINST HIV/SIVDennis Burton; Fiscal Year: 2005..This will provide us with the first opportunity to look at the effects of potent human mAbs on established infection in the presence of functional T cells. ..
- RECOVERY OF DAMAGE TO THE VESTIBULAR-AUDITORY SYSTEMNEAL BARMACK; Fiscal Year: 2003..abstract_text> ..
- Physiology of Lamina I and V STT CellsArthur Craig; Fiscal Year: 2005..This research will provide new insights into the synergy between lamina I and V STT neurons and into the integration underlying pain, temperature and itch sensations that is altered in clinical disorders. ..
- CELLULAR REGULATION OF TYROSINE HYDROXYLASEJohn Haycock; Fiscal Year: 2001..The effects of haloperidol on Ser19, Ser3l, and Ser4O phosphorylation will be studied by immunohistochemical and blot immunolabeling procedures using site- and phosphorylation state-specific antibodies. ..
- Effects of Dietary Soy on Biomarkers in Prostate CancerJ Cline; Fiscal Year: 2004..abstract_text> ..
- Mechanisms of Growth Inhibition by Helicobacter PylorHassan Ashktorab; Fiscal Year: 2003..These studies will help to establish how bacteria can increase apoptosis possibly through generation of ROS and in specific circumstances this may alter one's risk of developing cancer. ..
- Role of Ang-(1-7) in normal and hypertensive pregnancyK Brosnihan; Fiscal Year: 2003..The major goal of these studies is to understand the contribution of the vasodilator component of the RAAS to blood pressure regulation in normal pregnancy. ..
- STRUCTURE AND FUNCTION OF ROD AND CONE PIGMENTSMasahiro Kono; Fiscal Year: 2004..These results will also be important in the understanding of the activation mechanisms of the larger field of G protein-coupled receptors. ..
- COGNITION AND ESTROGEN IN MIDDLE-AGED FEMALE MONKEYSMary Lou Voytko; Fiscal Year: 2003..The findings from these novel experiments in middle-aged monkeys will significantly advance our understanding of the effects of different ovarian hormone therapies on cognitive and neurobiological profiles of primates. ..
- Accumbens-pallidal GABA and morphine reinforcementScott Hemby; Fiscal Year: 2005..Changes in the expression levels of multiple genes will be assessed in terms of morphine reinforcement and direct pharmacological effects of the drug. ..
- Adjuvant Therapy for Vascular Inflammation in DiabetesSushil Jain; Fiscal Year: 2006..abstract_text> ..
- NEUROBIOLOGY OF PRIMATE SOCIAL BEHAVIORDavid Amaral; Fiscal Year: 2002..These studies will provide important insights into the neurobiology of normal social behavior and may contribute to an understanding of pathologies of social communication in disorders such as autism. ..
- Neural Basis of Semantic Constraints on Adjective OrderDavid Kemmerer; Fiscal Year: 2006..This will be done by recording event-related potentials in normal adults while they read examples of natural and unnatural adjective orders. [unreadable] [unreadable]..
- VESTIBULAR MECHANISMS IN THE DYNAMICS OF LOCOMOTIONTheodore Raphan; Fiscal Year: 2006....
- GLOBIN SWITCHING AND ERYTHROID DIFFERENTIATIONThalia Papayannopoulou; Fiscal Year: 2002....
- TRAINING PROGRAM IN SYSTEMS NEUROSCIENCEDavid Amaral; Fiscal Year: 2002..abstract_text> ..
- Multilevel Dynamics of Conditional Control MechanismsGin McCollum; Fiscal Year: 2006....
- Studies on the Eppin family of proteins on chromosome 20MICHAEL G O apos RAND; Fiscal Year: 2010..This aim will test the hypothesis that anti-Eppin antibodies disrupt Eppin's modulation of PSA activity. ..
- BEHAVIORAL EFFECTS AND ABUSE OF DOPAMINERGIC DRUGSJack Bergman; Fiscal Year: 2007..This research should point to novel directions for the development of medications with which to manage the abuse and addictive liabilities of psychomotor stimulant drugs ..
- Functional architecture of switching between two tasksGlenn Wylie; Fiscal Year: 2004..Thus, our pilot data suggest that we have found two robust methods for investigating control processes, and it is the purpose of this proposal to use these paradigms to gain a better understanding of executive control. ..
- Reduction and Telemetry of Neural Data for an Implantable Data Acquisition SystemMICHAEL RIZK; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- MECHANISMS OF PERCEPTUAL ORGANIZATION IN HUMAN VISIONRobert Blake; Fiscal Year: 2005..In addition, the work on spatial structure from temporal synchrony may have implications for understanding clinical disorders involving disruptions in temporal processing, including dyslexia. ..
- COCHLEAR MECHANICSWILLIAM RHODE; Fiscal Year: 2007..Mechanical measurements will be compared I to auditory nerve responses in the same species and using the same signals. ..
- Female sexuality: modulation by estrogen and androgenKim Wallen; Fiscal Year: 2005..These therapies will also be compared on their effects on neuroendocrine function. These studies will markedly increase our understanding of the role that ovarian steroids play in modulating women's sexuality. ..
- SOY, LIFE STAGE, STRESS AND ATHEROSCLEROSIS IN FEMALESJAY KAPLAN; Fiscal Year: 2009....
- ARBOVIRUS PERSISTENCE IN SEASONAL WETLANDSWilliam Reisen; Fiscal Year: 2002..Virus ecology at wetlands in the Coachella Valley of southeastern California with consistent enzootic activity will be compared with wetlands in the southern San Joaquin Valley where virus activity currently is intermittent. ..