birds

Summary

Summary: Warm-blooded VERTEBRATES possessing FEATHERS and belonging to the class Aves.

Top Publications

  1. ncbi The global diversity of birds in space and time
    W Jetz
    Department of Ecology and Evolutionary Biology, Yale University, 165 Prospect Street, New Haven, Connecticut 06520 8106, USA
    Nature 491:444-8. 2012
  2. ncbi Origin of the West Nile virus responsible for an outbreak of encephalitis in the northeastern United States
    R S Lanciotti
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80522, USA
    Science 286:2333-7. 1999
  3. ncbi A phylogenomic study of birds reveals their evolutionary history
    Shannon J Hackett
    Zoology Department, Field Museum of Natural History, 1400 South Lake Shore Drive, Chicago, IL 60605, USA
    Science 320:1763-8. 2008
  4. ncbi Global patterns of influenza a virus in wild birds
    Bjorn Olsen
    Department of Infectious Diseases, Umea University, SE 90187 Umea, Sweden
    Science 312:384-8. 2006
  5. pmc The genome of the green anole lizard and a comparative analysis with birds and mammals
    Jessica Alföldi
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA
    Nature 477:587-91. 2011
  6. pmc Phylogenomic analyses support the position of turtles as the sister group of birds and crocodiles (Archosauria)
    Ylenia Chiari
    Institut des Sciences de l Evolution, UMR5554 CNRS IRD, Universite Montpellier 2, Montpellier, France
    BMC Biol 10:65. 2012
  7. pmc Experimental infection of North American birds with the New York 1999 strain of West Nile virus
    Nicholas Komar
    Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA
    Emerg Infect Dis 9:311-22. 2003
  8. pmc Identification of Birds through DNA Barcodes
    Paul D N Hebert
    Department of Zoology, University of Guelph, Guelph, Ontario, Canada
    PLoS Biol 2:e312. 2004
  9. pmc Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome
    Ron A M Fouchier
    Department of Virology and National Influenza Center, Erasmus Medical Center, Dr Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands
    Proc Natl Acad Sci U S A 101:1356-61. 2004
  10. ncbi A global perspective on the epidemiology of West Nile virus
    Laura D Kramer
    The Arbovirus Laboratories, Wadsworth Center, New York State Department of Health, Slingerlands, NY 12159, USA
    Annu Rev Entomol 53:61-81. 2008

Research Grants

  1. NIH Director's Pioneer Award
    ERICH JARVIS; Fiscal Year: 2009
  2. Recombinant Attenuated Salmonella Vaccines for Humans
    Roy Curtiss; Fiscal Year: 2012
  3. Estrogen Modulation of Auditory Processing
    Raphael Pinaud; Fiscal Year: 2012
  4. Genomic approaches to inner ear hair cell regeneration
    Michael Lovett; Fiscal Year: 2010
  5. INTRACELLULAR CALCIUM IN HAIR CELLS
    Robert Fettiplace; Fiscal Year: 2013
  6. Coronavirus RNA Replication
    DAVID ALVIN BRIAN; Fiscal Year: 2012
  7. Regeneration of stereocilia of cochlear hair cells
    David Z Z He; Fiscal Year: 2010
  8. The Evolutionary and Biological Bases of Host Switching in Viruses
    Colin R Parrish; Fiscal Year: 2013
  9. Development of Cross Protective H5 Hemagglutinin Antigens
    Susan C Bock; Fiscal Year: 2010
  10. Astrovirus structure and replication
    Yizhi Jane Tao; Fiscal Year: 2013

Detail Information

Publications369 found, 100 shown here

  1. ncbi The global diversity of birds in space and time
    W Jetz
    Department of Ecology and Evolutionary Biology, Yale University, 165 Prospect Street, New Haven, Connecticut 06520 8106, USA
    Nature 491:444-8. 2012
    ..Here we present, analyse and map the first complete dated phylogeny of all 9,993 extant species of birds, a widely studied group showing many unique adaptations...
  2. ncbi Origin of the West Nile virus responsible for an outbreak of encephalitis in the northeastern United States
    R S Lanciotti
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80522, USA
    Science 286:2333-7. 1999
    ..that was concurrent with extensive mortality in crows (Corvus species) as well as the deaths of several exotic birds at a zoological park in the same area...
  3. ncbi A phylogenomic study of birds reveals their evolutionary history
    Shannon J Hackett
    Zoology Department, Field Museum of Natural History, 1400 South Lake Shore Drive, Chicago, IL 60605, USA
    Science 320:1763-8. 2008
    ..challenge current classifications and alter our understanding of trait evolution; for example, some diurnal birds evolved from nocturnal ancestors...
  4. ncbi Global patterns of influenza a virus in wild birds
    Bjorn Olsen
    Department of Infectious Diseases, Umea University, SE 90187 Umea, Sweden
    Science 312:384-8. 2006
    ..subsequently spread to Russia, the Middle East, Europe, and Africa, has put increased focus on the role of wild birds in the persistence of influenza viruses...
  5. pmc The genome of the green anole lizard and a comparative analysis with birds and mammals
    Jessica Alföldi
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA
    Nature 477:587-91. 2011
    ..Among amniotes, genome sequences are available for mammals and birds, but not for non-avian reptiles...
  6. pmc Phylogenomic analyses support the position of turtles as the sister group of birds and crocodiles (Archosauria)
    Ylenia Chiari
    Institut des Sciences de l Evolution, UMR5554 CNRS IRD, Universite Montpellier 2, Montpellier, France
    BMC Biol 10:65. 2012
    ..as either the sister group to all other reptiles, to lepidosaurs (tuatara, lizards and snakes), to archosaurs (birds and crocodiles), or to crocodilians...
  7. pmc Experimental infection of North American birds with the New York 1999 strain of West Nile virus
    Nicholas Komar
    Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA
    Emerg Infect Dis 9:311-22. 2003
    ..Passeriform and charadriiform birds were more reservoir competent (a derivation of viremia data) than other species tested...
  8. pmc Identification of Birds through DNA Barcodes
    Paul D N Hebert
    Department of Zoology, University of Guelph, Guelph, Ontario, Canada
    PLoS Biol 2:e312. 2004
    ..We determined COI barcodes for 260 species of North American birds and found that distinguishing species was generally straightforward...
  9. pmc Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome
    Ron A M Fouchier
    Department of Virology and National Influenza Center, Erasmus Medical Center, Dr Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands
    Proc Natl Acad Sci U S A 101:1356-61. 2004
    ..Because H7N7 viruses have caused disease in mammals, including horses, seals, and humans, on several occasions in the past, they may be unusual in their zoonotic potential and, thus, form a pandemic threat to humans...
  10. ncbi A global perspective on the epidemiology of West Nile virus
    Laura D Kramer
    The Arbovirus Laboratories, Wadsworth Center, New York State Department of Health, Slingerlands, NY 12159, USA
    Annu Rev Entomol 53:61-81. 2008
    ..Vector control strategies, vaccines, and antivirals, which now must be considered on a global scale, are also discussed...
  11. pmc Lineage 1 and 2 strains of encephalitic West Nile virus, central Europe
    Tamas Bakonyi
    University of Veterinary Medicine, Vienna, Austria
    Emerg Infect Dis 12:618-23. 2006
    ..The emergence of an exotic WNV strain in Hungary emphasizes the role of migrating birds in introducing new viruses to Europe.
  12. pmc Birds track their Grinnellian niche through a century of climate change
    Morgan W Tingley
    Department of Environmental Science, Policy, and Management and Integrative Biology, and Museum of Vertebrate Zoology, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 106:19637-43. 2009
    ....
  13. pmc Spatial, temporal, and species variation in prevalence of influenza A viruses in wild migratory birds
    Vincent J Munster
    Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    PLoS Pathog 3:e61. 2007
    Although extensive data exist on avian influenza in wild birds in North America, limited information is available from elsewhere, including Europe...
  14. ncbi Random forests for classification in ecology
    D Richard Cutler
    Department of Mathematics and Statistics, Utah State University, Logan, Utah 84322 3900, USA
    Ecology 88:2783-92. 2007
    ..California, USA, rare lichen species presence in the Pacific Northwest, USA, and nest sites for cavity nesting birds in the Uinta Mountains, Utah, USA...
  15. ncbi A DNA test to sex most birds
    R Griffiths
    Molecular Laboratory, DEEB, Glasgow University, UK
    Mol Ecol 7:1071-5. 1998
    b>Birds are difficult to sex. Nestlings rarely show sex-linked morphology and we estimate that adult females appear identical to males in over 50% of the world's bird species...
  16. pmc Rapid microsatellite identification from Illumina paired-end genomic sequencing in two birds and a snake
    Todd A Castoe
    Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado, United States of America
    PLoS ONE 7:e30953. 2012
    ..Given that Illumina Seq-to-SSR is effective, inexpensive, and reliable even for species such as birds that have few SSR loci, it seems that there are now few situations for which prior hybridization is justifiable.
  17. pmc Epizootic emergence of Usutu virus in wild and captive birds in Germany
    Norbert Becker
    German Mosquito Control Association, KABS, Waldsee, Germany
    PLoS ONE 7:e32604. 2012
    This study aimed to identify the causative agent of mass mortality in wild and captive birds in southwest Germany and to gather insights into the phylogenetic relationship and spatial distribution of the pathogen...
  18. pmc The evolutionary genetics and emergence of avian influenza viruses in wild birds
    Vivien G Dugan
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    PLoS Pathog 4:e1000076. 2008
    We surveyed the genetic diversity among avian influenza virus (AIV) in wild birds, comprising 167 complete viral genomes from 14 bird species sampled in four locations across the United States...
  19. ncbi An overview of the epidemiology of avian influenza
    Dennis J Alexander
    Virology Department, VLA Weybridge, Addlestone, Surrey, UK
    Vaccine 25:5637-44. 2007
    Only viruses of the Influenzavirus A genus have been isolated from birds and termed avian influenza [AI] viruses, but viruses with all 16 haemagglutinin [H1-H16] and all 9 neuraminidase [N1-N9] influenza A subtypes in the majority of ..
  20. pmc Emergence of Usutu virus, an African mosquito-borne flavivirus of the Japanese encephalitis virus group, central Europe
    Herbert Weissenbock
    Institute of Pathology and Forensic Veterinary Medicine, Vienna, Austria
    Emerg Infect Dis 8:652-6. 2002
    During late summer 2001 in Austria, a series of deaths in several species of birds occurred, similar to the beginning of the West Nile virus (WNV) epidemic in the United States...
  21. pmc Introduction of West Nile virus in the Middle East by migrating white storks
    Mertyn Malkinson
    Kirmon Veterinary Institute, Beit Dagan, Isreal
    Emerg Infect Dis 8:392-7. 2002
    ..Since these storks were migrating southwards for the first time and had not flown over Israel, we assume that they had become infected with WNV at some point along their route of migration in Europe...
  22. pmc Evolution of modern birds revealed by mitogenomics: timing the radiation and origin of major orders
    M Andreina Pacheco
    Center for Evolutionary Medicine and Informatics, The Biodesign Institute, Arizona State University, AZ, USA
    Mol Biol Evol 28:1927-42. 2011
    Mitochondrial (mt) genes and genomes are among the major sources of data for evolutionary studies in birds. This places mitogenomic studies in birds at the core of intense debates in avian evolutionary biology...
  23. ncbi West Nile virus emergence and large-scale declines of North American bird populations
    Shannon L LaDeau
    Smithsonian Migratory Bird Center, National Zoological Park, Washington, DC 20008, USA
    Nature 447:710-3. 2007
    ..Our findings demonstrate the potential impacts of an invasive species on a diverse faunal assemblage across broad geographical scales, and underscore the complexity of subsequent community response...
  24. pmc The pathogenesis of influenza virus infections: the contributions of virus and host factors
    Satoshi Fukuyama
    ERATO Infection Induced Host Responses Project, Japan Science and Technology Agency, Saitama 332 0012, Japan
    Curr Opin Immunol 23:481-6. 2011
    ..Here, we review the contributions of both virus and host factors to the pathogenesis of these viral infections...
  25. pmc Migratory flyway and geographical distance are barriers to the gene flow of influenza virus among North American birds
    Tommy Tsan Yuk Lam
    Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, PA 16802, USA
    Ecol Lett 15:24-33. 2012
    Despite the importance of migratory birds in the ecology and evolution of avian influenza virus (AIV), there is a lack of information on the patterns of AIV spread at the intra-continental scale...
  26. pmc Mutation rate is linked to diversification in birds
    Robert Lanfear
    Centre for Macroevolution and Macroecology, Ecology Evolution and Genetics, Research School of Biology, Australian National University, Canberra ACT 0200, Australia
    Proc Natl Acad Sci U S A 107:20423-8. 2010
    ..rate of molecular evolution and net diversification with a 19-gene, 17-kb DNA sequence dataset from 64 families of birds. We show that rates of molecular evolution are positively correlated to net diversification in birds. Using a 7...
  27. ncbi The proliferative ventricular zone in adult vertebrates: a comparative study using reptiles, birds, and mammals
    Jose Manuel Garcia-Verdugo
    Departamento de Biologia Celular, Facultad de Ciencias Biologicas, Universidad de Valencia, Valencia, Spain
    Brain Res Bull 57:765-75. 2002
    ..Here we review the organization and cellular composition of the ventricular wall of reptiles, birds, and mammals in an effort to identify differences and commonalities among these vertebrate classes...
  28. ncbi Calibrating the avian molecular clock
    J T Weir
    Department of Ecology and Evolution, University of Chicago, Chicago, IL 60637, USA
    Mol Ecol 17:2321-8. 2008
    ..Minor but significant variance in rates occurred across lineages but was not explained by differences in generation time, body size or latitudinal distribution as previously suggested...
  29. ncbi Extra pair paternity in birds: a review of interspecific variation and adaptive function
    Simon C Griffith
    Department of Zoology, University of Oxford, Oxford, OX1 3PS, UK
    Mol Ecol 11:2195-212. 2002
    ..Contrary to prior expectations, birds are only very rarely sexually monogamous, with 'extra-pair offspring' found in approximately 90% of species...
  30. ncbi H5N1 influenza--continuing evolution and spread
    Robert G Webster
    Department of Infectious Diseases, Division of Virology, St Jude Children s Research Hospital, Memphis, TN, USA
    N Engl J Med 355:2174-7. 2006
  31. pmc Host heterogeneity dominates West Nile virus transmission
    A Marm Kilpatrick
    Consortium for Conservation Medicine, New York, NY 10001, USA
    Proc Biol Sci 273:2327-33. 2006
    ....
  32. pmc Persistence of highly pathogenic avian influenza viruses in natural ecosystems
    Camille Lebarbenchon
    Centre de Recherche de la Tour du Valat, Arles, France
    Emerg Infect Dis 16:1057-62. 2010
    ..low pathogenic avian influenza viruses persist and evolve in wild populations, HPAI viruses evolve in domestic birds and cause economically serious epizootics that only occasionally infect wild populations...
  33. ncbi Global hotspots of species richness are not congruent with endemism or threat
    C David L Orme
    Division of Biology and
    Nature 436:1016-9. 2005
    ..Consequently, the different types of hotspots also vary greatly in their utility as conservation tools...
  34. ncbi Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses
    M Hatta
    Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Drive, Madison, WI 53706, USA
    Science 293:1840-2. 2001
    In 1997, an H5N1 influenza A virus was transmitted from birds to humans in Hong Kong, killing 6 of the 18 people infected. When mice were infected with the human isolates, two virulence groups became apparent...
  35. pmc Comparative genomics based on massive parallel transcriptome sequencing reveals patterns of substitution and selection across 10 bird species
    Axel Künstner
    Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Sweden
    Mol Ecol 19:266-76. 2010
    ..Overall, this study demonstrates the usefulness of next-generation sequencing for obtaining genomic resources for comparative genomic analysis of non-model organisms...
  36. ncbi Avian flu: influenza virus receptors in the human airway
    Kyoko Shinya
    Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Nature 440:435-6. 2006
    ..Our findings may provide a rational explanation for why H5N1 viruses at present rarely infect and spread between humans although they can replicate efficiently in the lungs...
  37. pmc Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals
    Debby van Riel
    Department of Virology, Erasmus MC, P O Box 2040, 3015 CA, Rotterdam, The Netherlands
    Am J Pathol 171:1215-23. 2007
    ..The PVA in human respiratory tract most closely mirrored that in ferrets and pigs for human influenza viruses and that in ferrets, pigs, and cats for avian influenza viruses...
  38. pmc Identifying the world's most climate change vulnerable species: a systematic trait-based assessment of all birds, amphibians and corals
    Wendy B Foden
    Global Species Programme, International Union for Conservation of Nature, Cambridge, United Kingdom
    PLoS ONE 8:e65427. 2013
    ..In the largest such assessment to date, we applied this approach to each of the world's birds, amphibians and corals (16,857 species)...
  39. ncbi Increasing awareness of avian ecological function
    Cagan H Sekercioglu
    Stanford University Center for Conservation Biology, Department of Biological Sciences, Stanford, CA 94305 5020, USA
    Trends Ecol Evol 21:464-71. 2006
    b>Birds are one of the most diverse groups of ecosystem service providers, whose ecological functions range from creating soil to shaping primate behavior, Nevertheless, the impression that birds have little influence on ecological ..
  40. pmc The role of host genetics in susceptibility to influenza: a systematic review
    Peter Horby
    Oxford University Clinical Research Unit Wellcome Trust Major Overseas Programme, Hanoi, Vietnam
    PLoS ONE 7:e33180. 2012
    ..A systematic review was conducted to summarize the current state of evidence on the role of host genetics in susceptibility to influenza (PROSPERO registration number: CRD42011001380)...
  41. ncbi Reintroduction of H5N1 highly pathogenic avian influenza virus by migratory water birds, causing poultry outbreaks in the 2010-2011 winter season in Japan
    Yoshihiro Sakoda
    Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060 0818, Japan
    J Gen Virol 93:541-50. 2012
    ..Since then, in Japan, H5N1 HPAIVs have been isolated from 63 wild birds in 17 prefectures and caused HPAI outbreaks in 24 chicken farms in nine prefectures by the end of March in 2011...
  42. ncbi Epidemic West Nile encephalitis, New York, 1999: results of a household-based seroepidemiological survey
    F Mostashari
    Communicable Disease Program, New York City Department of Health, NY 10013, USA
    Lancet 358:261-4. 2001
    ..We did a household-based seroepidemiological survey to assess more clearly the public-health impact of the epidemic, its range of illness, and risk factors associated with infection...
  43. pmc Antecedent avian immunity limits tangential transmission of West Nile virus to humans
    Jennifer L Kwan
    Center for Vectorborne Diseases, Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America
    PLoS ONE 7:e34127. 2012
    West Nile virus (WNV) is a mosquito-borne flavivirus maintained and amplified among birds and tangentially transmitted to humans and horses which may develop terminal neuroinvasive disease...
  44. ncbi Usutu virus in Africa
    Birgit Nikolay
    Unité des Arbovirus et Virus de Fièvres Hémorragiques, Institut Pasteur de Dakar, Dakar, Senegal
    Vector Borne Zoonotic Dis 11:1417-23. 2011
    ..The host range in Africa includes mainly Culex mosquitoes, birds, and also humans with one benign and one severe case...
  45. ncbi Challenging claims in the study of migratory birds and climate change
    Endre Knudsen
    Centre for Ecological and Evolutionary Synthesis CEES, Department of Biology, University of Oslo, Norway
    Biol Rev Camb Philos Soc 86:928-46. 2011
    ..and discuss key statements emerging from the rapidly developing study of changing spring phenology in migratory birds. These well-studied organisms have been instrumental for understanding climate-change effects, but research is ..
  46. ncbi Mitochondrial DNA under siege in avian phylogeography
    Robert M Zink
    Bell Museum of Natural History, University of Minnesota, St Paul, MN 55108, USA
    Mol Ecol 17:2107-21. 2008
    ..Here we review the relative merits of mitochondrial and nuclear phylogeographical studies, using birds as an exemplar class of organisms...
  47. pmc Fine-scale variation in vector host use and force of infection drive localized patterns of West Nile virus transmission
    Gabriel L Hamer
    Department of Pathobiological Sciences, University of Wisconsin, Madison, Wisconsin, United States of America
    PLoS ONE 6:e23767. 2011
    ..Rather, robust assessment of local transmission risk should incorporate heterogeneity in vector host feeding and variation in vertebrate reservoir competence at the spatial scale of vector-host interaction...
  48. ncbi Predators and the breeding bird: behavioral and reproductive flexibility under the risk of predation
    Steven L Lima
    Department of Biology, Indiana State University, Terre Haute, Indiana 47809, USA
    Biol Rev Camb Philos Soc 84:485-513. 2009
    A growing body of work suggests that breeding birds have a significant capacity to assess and respond, over ecological time, to changes in the risk of predation to both themselves and their eggs or nestlings...
  49. pmc A method for investigating population declines of migratory birds using stable isotopes: origins of harvested lesser scaup in North America
    Keith A Hobson
    Environment Canada, Saskatoon, Saskatchewan, Canada
    PLoS ONE 4:e7915. 2009
    Elucidating geographic locations from where migratory birds are recruited into adult breeding populations is a fundamental but largely elusive goal in conservation biology...
  50. pmc Disentangling vector-borne transmission networks: a universal DNA barcoding method to identify vertebrate hosts from arthropod bloodmeals
    Miguel Alcaide
    Estacion Biologica de Donana CSIC, Isla de la Cartuja, Sevilla, Spain
    PLoS ONE 4:e7092. 2009
    ..Such information is crucial to support the efficient management of initiatives aimed at reducing epidemiologic risks of arthropod vector-borne pathogens, a priority for public health...
  51. pmc Highly pathogenic avian influenza (H5N1): pathways of exposure at the animal-human interface, a systematic review
    Maria D Van Kerkhove
    MRC Centre for Outbreak Analysis and Modelling, Imperial College London, London, United Kingdom
    PLoS ONE 6:e14582. 2011
    ..Therefore, we review risk factors for H5N1 infection in humans...
  52. pmc Evidence for avian and human host cell factors that affect the activity of influenza virus polymerase
    Olivier Moncorgé
    Department of Virology, Division of Infectious Diseases, Imperial College London, Wright Fleming Institute, Norfolk Place, W2 1PG London, UK
    J Virol 84:9978-86. 2010
    ..Finally, our results strongly suggest that the well-known adaptative mutation E627K on viral protein PB2 facilitates the ability of a human positive factor to enhance replication of influenza virus in human cells...
  53. ncbi Influenza A viruses of migrating wild aquatic birds in North America
    Scott Krauss
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Vector Borne Zoonotic Dis 4:177-89. 2004
    ..The viruses reported in this study are available for genomic study to determine whether prediction of host range or pandemic potential is possible...
  54. pmc Species richness, hotspots, and the scale dependence of range maps in ecology and conservation
    Allen H Hurlbert
    National Center for Ecological Analysis and Synthesis, 735 State Street, Santa Barbara, CA 93101, USA
    Proc Natl Acad Sci U S A 104:13384-9. 2007
    ..We suggest that range-map data contain less information than is generally assumed and provide guidance about the appropriate scale of their use...
  55. ncbi Evolutionary relationships, cospeciation, and host switching in avian malaria parasites
    Robert E Ricklefs
    Department of Biology, University of Missouri, 8001 Natural Bridge Road, St Louis, Missouri 63121 4499, USA
    Syst Biol 53:111-9. 2004
    ..Detailed studies of the phylogeographic distributions of hosts and parasites are needed to characterize these events...
  56. pmc Detection of influenza A viruses from different species by PCR amplification of conserved sequences in the matrix gene
    R A Fouchier
    National Influenza Center and Department of Virology, Erasmus University, Rotterdam, The Netherlands
    J Clin Microbiol 38:4096-101. 2000
    ..This PCR proved to be fully reactive with a panel of 25 genetically diverse virus isolates that were obtained from birds, humans, pigs, horses, and seals and that included all known subtypes of influenza A virus...
  57. ncbi Revisiting Lévy flight search patterns of wandering albatrosses, bumblebees and deer
    Andrew M Edwards
    British Antarctic Survey, High Cross, Madingley Road, Cambridge CB3 0ET, UK
    Nature 449:1044-8. 2007
    ..Our results question the strength of the empirical evidence for biological Lévy flights...
  58. ncbi Photoperiodic control of seasonality in birds
    A Dawson
    Centre for Ecology and Hydrology, Huntingdon, Cambridgeshire, UK
    J Biol Rhythms 16:365-80. 2001
    This review examines how birds use the annual cycle in photoperiod to ensure that seasonal events--breeding, molt, and song production--happen at the appropriate time of year...
  59. pmc Sialic acid receptor detection in the human respiratory tract: evidence for widespread distribution of potential binding sites for human and avian influenza viruses
    John M Nicholls
    Pathology Department, The University of Hong Kong, Pok Fu Lam, Hong Kong, Hong Kong SAR
    Respir Res 8:73. 2007
    ....
  60. ncbi Cities change the songs of birds
    Hans Slabbekoorn
    Behavioural Biology, Institute of Biology, Leiden University, 2300 RA Leiden, The Netherlands
    Curr Biol 16:2326-31. 2006
    ..At the same time, they reveal a behavioral plasticity that may be key to urban success and the lack of which may explain detrimental effects on bird communities that live in noisy urbanized areas or along highways...
  61. ncbi Global seabird response to forage fish depletion--one-third for the birds
    Philippe M Cury
    Institut de Recherche pour le Developpement, UMR EME 212, Centre de Recherche Halieutique Méditerranéenne et Tropicale, Avenue Jean Monnet, Sète Cedex, France
    Science 334:1703-6. 2011
    ..The threshold approximated one-third of the maximum prey biomass observed in long-term studies. This provides an indicator of the minimal forage fish biomass needed to sustain seabird productivity over the long term...
  62. ncbi 2009 West Nile disease epidemic in Italy: first evidence of overwintering in Western Europe?
    F Monaco
    Istituto Zooprofilattico Sperimentale dell Abruzzo e Molise G Caporale, Via Campo Boario, 64100 Teramo, Italy
    Res Vet Sci 91:321-6. 2011
    ....
  63. ncbi Avian malaria parasites share congeneric mosquito vectors
    M Kimura
    Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, New York 14853, USA
    J Parasitol 96:144-51. 2010
    ..We tested this prediction by asking if 5 different mosquito species, known to feed on birds and abundant in the northeastern United States, were naturally infected in the field with identical avian ..
  64. pmc Potential impacts of climatic change on European breeding birds
    Brian Huntley
    Institute of Ecosystem Science, School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom
    PLoS ONE 3:e1439. 2008
    ..Such estimates are of greatest value when they are made for large ensembles of species and for extensive (sub-continental or continental) regions...
  65. ncbi Molecular evolution of the toll-like receptor multigene family in birds
    Miguel Alcaide
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Muscat
    Mol Biol Evol 28:1703-15. 2011
    ....
  66. ncbi West Nile in the Mediterranean basin: 1950-2000
    B Murgue
    Centre National de Référence des Arbovirus et des Fièvres hémorragiques virales, Institut Pasteur, Paris, France
    Ann N Y Acad Sci 951:117-26. 2001
    ..It is distinguishable from the group including the Israel-1998 and New York-1999 isolates, as well as the Tunisia-1997 human isolate...
  67. ncbi Emerging vectors in the Culex pipiens complex
    Dina M Fonseca
    Genetics Program, Smithsonian Institution, National Museum of Natural History, 3001 Connecticut Avenue N W, Washington, DC 20008 0551, USA
    Science 303:1535-8. 2004
    ..in the Culex pipiens complex are excellent enzootic vectors of West Nile virus, circulating the virus among birds, whereas others bite mainly humans and other mammals...
  68. ncbi A basal dromaeosaurid and size evolution preceding avian flight
    Alan H Turner
    Division of Paleontology, American Museum of Natural History, Central Park West at 79th Street, New York, NY 10024 5192, USA
    Science 317:1378-81. 2007
    Fossil evidence for changes in dinosaurs near the lineage leading to birds and the origin of flight has been sparse. A dinosaur from Mongolia represents the basal divergence within Dromaeosauridae...
  69. pmc Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes
    Frederic Veyrunes
    Research School of Biological Sciences, Australian National University, Canberra 2601, Australia
    Genome Res 18:965-73. 2008
    ..There is no equivalent in other amniotes, although some taxa (notably birds and snakes) have differentiated sex chromosomes...
  70. pmc Environmental transmission of low pathogenicity avian influenza viruses and its implications for pathogen invasion
    Pejman Rohani
    Odum School of Ecology, University of Georgia, Athens, GA 30602, USA
    Proc Natl Acad Sci U S A 106:10365-9. 2009
    ....
  71. ncbi Commercialization of animal-derived remedies as complementary medicine in the semi-arid region of Northeastern Brazil
    Rômulo R N Alves
    Departamento de Biologia, Universidade Estadual da Paraiba, Avenida das Baraúnas, Campina Grande, Paraíba 58109 753, Brazil romulo
    J Ethnopharmacol 124:600-8. 2009
    ..While widespread and of great importance to large population that has limited access to contemporary medicine, such practices are poorly understood and the potential value of medicinal animal species largely unknown...
  72. ncbi A pre-Archaeopteryx troodontid theropod from China with long feathers on the metatarsus
    Dongyu Hu
    Paleontological Institute, Shenyang Normal University, 253 North Huanghe Street, Shenyang 110034, China
    Nature 461:640-3. 2009
    ..The specimen is referable to the Troodontidae, which are among the theropods most closely related to birds. This new find refutes the 'temporal paradox'1 and provides significant information on the temporal framework of ..
  73. pmc H5N1 outbreaks and enzootic influenza
    Robert G Webster
    St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Emerg Infect Dis 12:3-8. 2006
    ..In fact, the root cause of the continuing H5N1 pandemic threat may be the way the pathogenicity of H5N1 viruses is masked by co-circulating influenza viruses or bad agricultural vaccines...
  74. ncbi Effects of environmental methylmercury on the health of wild birds, mammals, and fish
    Anton M Scheuhammer
    National Wildlife Research Centre, Environment Canada, Carleton University, Ottawa
    Ambio 36:12-8. 2007
    Wild piscivorous fish, mammals, and birds may be at risk for elevated dietary methylmercury intake and toxicity...
  75. ncbi Sources of potentially infectious human microsporidia: molecular characterisation of microsporidia isolates from exotic birds in the Czech Republic, prevalence study and importance of birds in epidemiology of the human microsporidial infections
    D Kasicková
    University of South Bohemia in Ceske Budejovice, Faculty of Biological Science, Branisovska 31, Ceske Budejovice, Czech Republic
    Vet Parasitol 165:125-30. 2009
    A total of 287 faecal specimens of captive exotic birds from the orders Psittaciformes, Passeriformes and Columbiformes were randomly collected from Bohemian pet stores, avian breeders and avian keepers and were screened for the presence ..
  76. pmc A phylogeny of birds based on over 1,500 loci collected by target enrichment and high-throughput sequencing
    John E McCormack
    Museum of Natural Science, Louisiana State University, Baton Rouge, Louisiana, USA
    PLoS ONE 8:e54848. 2013
    Evolutionary relationships among birds in Neoaves, the clade comprising the vast majority of avian diversity, have vexed systematists due to the ancient, rapid radiation of numerous lineages...
  77. ncbi Fine-scale genetic variation and evolution of West Nile Virus in a transmission "hot spot" in suburban Chicago, USA
    Luigi Bertolotti
    Universita degli Studi di Torino, Dipartimento di Produzioni Animali, Epidemiologia, Ecologia, Via Leonardo da Vinci, 44, 10095 Grugliasco TO, Italy
    Virology 374:381-9. 2008
    Mosquitoes and birds were sampled for West Nile virus (WNV) in suburban Chicago, USA, in a "hot spot" of arboviral transmission. Viral genetic diversity within this area was similar to that within Illinois and the United States...
  78. pmc Sex bias and dosage compensation in the zebra finch versus chicken genomes: general and specialized patterns among birds
    Yuichiro Itoh
    Department of Integrative Biology and Physiology, University of California, Los Angeles, CA 90095 1606, USA
    Genome Res 20:512-8. 2010
    ..These patterns suggest that different avian taxa may have evolved specific compensatory mechanisms...
  79. pmc Host and habitat specialization of avian malaria in Africa
    Claire Loiseau
    Department of Biology, San Francisco State University, 1600 Holloway Avenue, San Francisco, CA 94132, USA
    Mol Ecol 21:431-41. 2012
    ..Thus, with environmental changes, we anticipate a change in the distribution of both specialist and generalist parasites with potential impacts on bird communities...
  80. ncbi West Nile virus: Uganda, 1937, to New York City, 1999
    C G Hayes
    Infectious Diseases Directorate, Naval Medical Research Center, Silver Spring, Maryland 20910 7500, USA
    Ann N Y Acad Sci 951:25-37. 2001
    ..geographical distribution, not uncommon infection of humans, transmission by mosquitoes, and association with wild birds as enzootic hosts were well documented by the mid-1960s...
  81. pmc Mosquito, bird and human surveillance of West Nile and Usutu viruses in Emilia-Romagna Region (Italy) in 2010
    Mattia Calzolari
    Istituto Zooprofilattico Sperimentale della Lombardia e dell Emilia Romagna B Ubertini, Brescia, Italy
    PLoS ONE 7:e38058. 2012
    ..Surveillance was improved in following years by extending the monitoring to larger areas and increasing the numbers of mosquitoes and birds tested.
  82. pmc Avian influenza viruses infect primary human bronchial epithelial cells unconstrained by sialic acid α2,3 residues
    Christine M Oshansky
    Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America
    PLoS ONE 6:e21183. 2011
    ....
  83. ncbi Neuroanatomy of flying reptiles and implications for flight, posture and behaviour
    Lawrence M Witmer
    Department of Biomedical Sciences, College of Osteopathic Medicine, Ohio University, Athens, Ohio 45701, USA
    Nature 425:950-3. 2003
    Comparison of birds and pterosaurs, the two archosaurian flyers, sheds light on adaptation to an aerial lifestyle...
  84. pmc Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air
    Neal Van Hoeven
    Influenza Division, Mailstop G 16, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road Northeast, Atlanta, GA 30333, USA
    Proc Natl Acad Sci U S A 106:3366-71. 2009
    ..These findings demonstrate that the adaptation of the HA and PB2 proteins are critical for the development of pandemic influenza strains from avian influenza viruses...
  85. ncbi Changes in wind pattern alter albatross distribution and life-history traits
    Henri Weimerskirch
    Centre d Etudes Biologiques de Chize, CNRS, 79360 Villiers en Bois, France
    Science 335:211-4. 2012
    ..Consequently, the duration of foraging trips has decreased, breeding success has improved, and birds have increased in mass by more than 1 kilogram...
  86. pmc Revised nomenclature for avian telencephalon and some related brainstem nuclei
    Anton Reiner
    Department of Anatomy, University of Tennessee Health Science Center, Memphis 38163, USA
    J Comp Neurol 473:377-414. 2004
    The standard nomenclature that has been used for many telencephalic and related brainstem structures in birds is based on flawed assumptions of homology to mammals...
  87. ncbi Thresholds in forest bird occurrence as a function of the amount of early-seral broadleaf forest at landscape scales
    M G Betts
    Department of Forest Ecosystems and Society, 312 Richardson Hall, Oregon State University, Corvallis, Oregon 97331, USA
    Ecol Appl 20:2116-30. 2010
    ..Forest management treatments that maintain or restore even small amounts of broadleaf vegetation could mitigate further declines...
  88. ncbi Ecological correlates of risk and incidence of West Nile virus in the United States
    Brian F Allan
    Department of Biology, Washington University, One Brookings Drive, Campus Box 1137, Saint Louis, MO, 63130, USA
    Oecologia 158:699-708. 2009
    ..Several species of birds appear to be the primary reservoir hosts, whereas other bird species, as well as other vertebrate species, can be ..
  89. ncbi Maternal hormones as a tool to adjust offspring phenotype in avian species
    Ton G G Groothuis
    Department of Behavioural Biology, University of Groningen, P O Box 14, 9750 AA Haren, The Netherlands
    Neurosci Biobehav Rev 29:329-52. 2005
    ..The field would greatly benefit from an analysis of the underlying physiological mechanisms...
  90. ncbi Phylogenetic analysis of influenza A viruses (H6N8, H1N8, H4N2, H9N2, H10N7) isolated from wild birds, ducks, and ostriches in South Africa from 2007 to 2009
    Celia Abolnik
    Agricultural Research Council Onderstepoort Veterinary Institute, Private Bag X05, Onderstepoort, Pretoria 0110, South Africa
    Avian Dis 54:313-22. 2010
    Influenza A strains emerging from wild birds are a constant threat to South Africa's valuable ostrich industry...
  91. ncbi A new PCR assay for simultaneous studies of Leucocytozoon, Plasmodium, and Haemoproteus from avian blood
    Olof Hellgren
    Department of Animal Ecology, Ecology Building, Lund University, SE 22362 Lund, Sweden
    J Parasitol 90:797-802. 2004
    ..Although only a small number of different bird species were investigated (6 passerine species), we found 22 different parasite species lineages (4 Haemoproteus, 8 Plasmodium, and 10 Leucocytozoon)...
  92. pmc Phylogenomics of nonavian reptiles and the structure of the ancestral amniote genome
    Andrew M Shedlock
    Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, Harvard University, 26 Oxford Street, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 104:2767-72. 2007
    ..The sequences reported in this paper have been deposited in the GenBank database (accession nos. CZ 250707-CZ 257443 and DX 390731-DX 389174)...
  93. pmc The birds and the bees and the flowers and the trees: lessons from genetic mapping of sex determination in plants and animals
    Deborah Charlesworth
    Department of Zoology, Edward Grey Institute, University of Oxford, Oxford OX1 3PS, United Kingdom
    Genetics 186:9-31. 2010
    ....
  94. pmc The survey of H5N1 flu virus in wild birds in 14 Provinces of China from 2004 to 2007
    Zheng Kou
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    PLoS ONE 4:e6926. 2009
    ..The highly pathogenic H5N1 avian influenza emerged in the year 1996 in Asia, and has spread to Europe and Africa recently. At present, effective monitoring and data analysis of H5N1 are not sufficient in Chinese mainland...
  95. ncbi Evolutionary stasis: the stable chromosomes of birds
    Hans Ellegren
    Department of Evolutionary Biology, Evolutionary Biology Centre, Norbyvagen 18D, SE 75236 Uppsala, Sweden
    Trends Ecol Evol 25:283-91. 2010
    ..However, in birds chromosomal evolution occurs at an unusually slow rate and recent whole-genome comparisons have shown that many ..
  96. ncbi FOXP2 as a molecular window into speech and language
    Simon E Fisher
    Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK
    Trends Genet 25:166-77. 2009
    ..This body of research represents the first functional genetic forays into neural mechanisms contributing to human spoken language...
  97. ncbi Adjustment to climate change is constrained by arrival date in a long-distance migrant bird
    C Both
    Zoological Laboratory, Groningen University, PO Box 14, 9750 AA Haren, The Netherlands
    Nature 411:296-8. 2001
    ....
  98. ncbi The physiological basis of diving to depth: birds and mammals
    G L Kooyman
    Scripps Institution of Oceanography, University of California, San Diego, La Jolla 92093 0204, USA
    Annu Rev Physiol 60:19-32. 1998
    ..Blood N2 levels remain below the threshold for decompression sickness. No such adaptive model is known for birds. There appear to be two diving strategies used by animals that dive to depth...
  99. ncbi Pathology and viral distribution in fatal Usutu virus infections of birds from the 2001 and 2002 outbreaks in Austria
    S Chvala
    Institute of Pathology and Forensic Veterinary Medicine, University of Veterinary Medecine, Veterinarplatz 1, Vienna A 1210, Austria
    J Comp Pathol 131:176-85. 2004
    ..In the present study, 40 of the birds (representing three species), confirmed as cases of USUV infection, were examined by four methods (histopathology, ..
  100. pmc Molecular mapping of movement-associated areas in the avian brain: a motor theory for vocal learning origin
    Gesa Feenders
    Volkswagen Nachwuchsgruppe Animal Navigation, Institut für Biologie und Umweltwissenschaften IBU, University of Oldenburg, Oldenburg, Germany
    PLoS ONE 3:e1768. 2008
    ..It is a rare trait found in three distantly related groups of birds-songbirds, hummingbirds, and parrots...
  101. ncbi Physiology of diving of birds and mammals
    P J Butler
    School of Biological Sciences, The University of Birmingham, Edgbaston, United Kingdom
    Physiol Rev 77:837-99. 1997
    This review concentrates on the physiological responses, and their control, in freely diving birds and mammals that enable them to remain submerged and sometimes quite active for extended periods of time...

Research Grants75

  1. NIH Director's Pioneer Award
    ERICH JARVIS; Fiscal Year: 2009
    ..groups of distantly related mammals (humans, cetaceans, elephants, and bats) and three groups of distantly related birds (parrots, hummingbirds, and songbirds) [unreadable] with the vast majority of species that do not have it - non-..
  2. Recombinant Attenuated Salmonella Vaccines for Humans
    Roy Curtiss; Fiscal Year: 2012
    ..by ensuring inability to persist and/or to completely lyse in vivo and especially in the intestinal tracts of birds and animals, (iii) to design and construct S...
  3. Estrogen Modulation of Auditory Processing
    Raphael Pinaud; Fiscal Year: 2012
    ..Second, a combination of intracerebral pharmacology in awake birds and biochemical methods will determine the specific intracellular mechanisms by which E2 influences auditory-..
  4. Genomic approaches to inner ear hair cell regeneration
    Michael Lovett; Fiscal Year: 2010
    ..Mammals cannot regenerate their hair cells. However, birds (and other lower vertebrates) can regenerate these cells...
  5. INTRACELLULAR CALCIUM IN HAIR CELLS
    Robert Fettiplace; Fiscal Year: 2013
    ..Hair cell responses will be measured in the isolated cochleae of both mammals and birds and will be combined with intracellular Ca2+ imaging...
  6. Coronavirus RNA Replication
    DAVID ALVIN BRIAN; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Coronaviruses, with the largest known viral RNA genome, infect birds and mammals, including humans, and cause diseases ranging from subclinical to lethal...
  7. Regeneration of stereocilia of cochlear hair cells
    David Z Z He; Fiscal Year: 2010
    ..in the last two decades have demonstrated that lost hair cells can be replaced by production of new hair cells in birds and lower vertebrates...
  8. The Evolutionary and Biological Bases of Host Switching in Viruses
    Colin R Parrish; Fiscal Year: 2013
    ..Although H3N8 EIV first emerged in horses from birds in 1963, only in the last ~10 years has it jumped to dogs, and on multiple occasions...
  9. Development of Cross Protective H5 Hemagglutinin Antigens
    Susan C Bock; Fiscal Year: 2010
    ..endemically in poultry of southeast Asia have recently been disseminated across the globe by wild migratory birds. These avian influenzas are also able to infect humans, and during the past decade have caused several outbreaks ..
  10. Astrovirus structure and replication
    Yizhi Jane Tao; Fiscal Year: 2013
    ..by applicant): Astroviruses are small, non-enveloped, positive-sense RNA viruses that infect humans, mammals and birds, posing a serious threat to human health and the well being of wild animals and economically important livestock...
  11. The role of the interaction between the C-terminal domain of RNA pol II and a his
    Uchechi E Ukaegbu; Fiscal Year: 2012
    ..domain (CTD) of the largest subunit of RNA pol II of primate parasites that is not found in parasites of rodents, birds or bats...
  12. Developing a Paramyxovirus-based H5N1 Vaccine
    Biao He; Fiscal Year: 2012
    ..avian influenza virus has most notably emerged in Southeast Asia and resulted in the destruction of millions of birds, infected 309 people, caused 187 human fatalities since 2003 (WHO, Cumulative Number of Confirmed Human Cases of ..
  13. Neural substrates for matching hearing to utterance
    Darcy B Kelley; Fiscal Year: 2012
    ..The match can be achieved via learning (as in song birds or humans) or be innate or largely unlearned (as in frogs or non-human primates), but in both cases strong ..
  14. REGULATION OF COCHLEAR REGENERATION BY CANONICAL WNT SIGNALING
    MATTHEW RYAN BARTON; Fiscal Year: 2012
    ..Although the mammalian inner ear is unable to replace lost or damaged hair cells, birds and other non-mammalian vertebrates can regenerate hair cells (HC) after injury...
  15. Regulation of cochlea hair cell differentiation by the Lin28b/let-7 axis
    Erin Golden; Fiscal Year: 2013
    ..While many vertebrates, including birds and reptiles, are able to regenerate damaged hair cells, mammals (including humans) do not retain this ability, ..
  16. Whole-genome analysis of direct Doublesex target genes
    MARK B VAN DOREN; Fiscal Year: 2012
    ..DMRT) family, which have been shown to regulate sexual dimorphism in organisms as diverse as flies, worms, fish, birds, mice and man...
  17. Social and Motivational Properties of Vasoactive Intestinal Polypeptide Circuits
    James L Goodson; Fiscal Year: 2013
    ..Limbic-hypothalamic circuits in birds and mammals are strongly conserved, allowing the behavioral robustness of finches to inform relevant studies in ..
  18. 9th International Symposium on Bordetella
    Nicholas H Carbonetti; Fiscal Year: 2010
    ..Beyond the original bordetellae, B. avium is an important cause of respiratory infections in birds and is responsible for tremendous economic losses for the poultry industry...
  19. Impact of corn grind diameter and housing environment on performance and presence
    Kenneth Anderson; Fiscal Year: 2013
    ..Laying hens will be inspected daily and birds with visual health problems or poor body condition will be humanely euthanized by cervical dislocation and ..
  20. Development of novel transsynaptic tracers for use in the central nervous system
    Constance L Cepko; Fiscal Year: 2013
    ..We found that VSV can transmit transsynaptically in mice, monkeys, and multiple other species, including birds, amphibians, and fish...
  21. Demography of Sex Differences in Health and Survival
    James W Vaupel; Fiscal Year: 2013
    ..How do they vary over place? * How have they varied over time? * How do they vary across species of mammals, birds, reptiles, amphibians and fish? Second, to the extent that the paradox is true, why is this the case? Various ..
  22. NEURAL STEROIDOGENIC ENZYMES AND BRAIN FUNCTION
    BARNETT ALAN SCHLINGER; Fiscal Year: 2013
    ..We propose performing microdialysis on the songbird hippocampus to measure steroids, glutamate and GABA as the birds perform natural hippocampal-based spatial and temporal memory intensive behaviors...
  23. Neural Coding and Perception of Learned Vocalizations
    SARAH M WOOLLEY; Fiscal Year: 2013
    ..We will train adult birds to recognize and respond to specific songs and then compare the responses of midbrain neurons to recognizable ..
  24. Inflammatory Response in Influenza Virus Infection
    Thomas M Moran; Fiscal Year: 2010
    ..Recently, highly pathogenic avian influenza viruses have arisen in aquatic birds and the subsequent zoonotic infections of humans have raised fear of a human pandemic...
  25. Multiple roles of inhibition in temporal coding of sensory information
    Ariel Lyons-Warren; Fiscal Year: 2012
    ..A temporal code uses precisely timed events to represent information. For example, sound localization in birds, mammals, and other vertebrates relies on temporal codes in which the events are spike times...
  26. The Structure and Function of the Influenza Virus Genome
    Robert A Lamb; Fiscal Year: 2013
    ..continuing great concern today is the highly virulent avian H5N1 influenza virus that is still circulating among birds and transmitting to humans in parts of Far East Asia...
  27. Gene Transfer Tools for Delivery and Investigation of Inner Ear MicroRNAs
    MICHELLE LYNN STOLLER; Fiscal Year: 2013
    ..Hair cells and supporting cells are created from the same progenitor pool during development and in birds, hair cell loss stimulates supporting cells to divide and regenerate additional hair cells...
  28. Quantitative Trait Genes for Circadian Phenotypes
    John R Hofstetter; Fiscal Year: 2013
    ..The first is a model for humans who are "early birds" and the other a model for "night owls". The goal is identifying genes that underlie this difference...
  29. Induced immunity as a source of maternal effects on offspring phenotype
    Charles Thompson; Fiscal Year: 2013
    ..excellent alternative model to evaluate maternal effects of prenatal stress because: (i) the endocrine systems of birds are similar to those of mammals, (ii) bird embryos are readily amenable to experimental manipulation within eggs, ..
  30. Translation of smart contrast agents for brain tumor characterization by MR
    Garry E Kiefer; Fiscal Year: 2013
    ..and TmDOTMA, provide extracellular pH/temperature maps with biosensor imaging of redundant deviation in shifts (BIRDS). These types of SCAs are used as MRS shift agents to separate resonances of endogenous molecules (or ions)...
  31. Basal Ganglia-Thalamic Interactions in Behaving Songbirds During Learning
    JESSE HEYMANN GOLDBERG; Fiscal Year: 2011
    ..is a clinically relevant group of deep brain structures that appear to play similar functions in humans and birds-motor sequence learning...
  32. Basal Ganglia-Thalamic Interactions in Behaving Songbirds During Learning
    JESSE HEYMANN GOLDBERG; Fiscal Year: 2013
    ..is a clinically relevant group of deep brain structures that appear to play similar functions in humans and birds-motor sequence learning...
  33. Role of Cytoplasmic Actin Isoforms in the Inner Ear
    Benjamin J Perrin; Fiscal Year: 2010
    ..isoforms vary at only 4 of 375 amino acid residues;however, these small sequence differences are conserved between birds and mammals, suggesting that [unreadable]cyto-- and ?cyto-actin nave distinct cellular functions...
  34. Uncovering mechanisms controlling notochord vacuole and spine morphogenesis
    Michel Bagnat; Fiscal Year: 2013
    ..These fluid-filled vacuoles have been described in every vertebrate embryo studied including fish, amphibians, birds, and mammals...
  35. Role of Shh-Hey1/Hey2 and Activin A in Hair Cell Differentiation
    Ana Benito-Gonzalez; Fiscal Year: 2013
    ..While many vertebrates, including birds and reptiles, are able to regenerate damaged hair cells, mammals (including humans) do not retain this ability, ..
  36. CELLULAR MECHANISMS OF THE VESTIBULAR SYSTEM
    Anna Lysakowski; Fiscal Year: 2013
    ..on the type I hair cell and its calyx ending, phylogenetically recent acquisitions only found in reptiles, birds and mammals. These structures are restricted to central/striolar zones in reptiles and birds...
  37. The Role of RNA Interference in West Nile Virus Diversification
    Douglas E Brackney; Fiscal Year: 2010
    ..WNV genetic diversity is greater in mosquitoes than birds in both nature and the laboratory...
  38. Notch signaling pathways in auditory support cell differentiation and maintenance
    Angelika Doetzlhofer; Fiscal Year: 2013
    ..Remarkably, non-mammalian vertebrates regenerate lost hair cells. In birds, supporting cells have been shown to replace lost hair cells by mechanisms involving either cell division or ..
  39. Bordetella pathogenesis: an undergraduate research tool
    Louise M Temple; Fiscal Year: 2010
    ..In the proposed study, we will collect a number of new B. avium isolates from wild birds and commercial turkeys, as well as creating deletion mutants of specific genes predicted to be important in ..
  40. Determining the genetic and developmental basis of epidermal appendage evolution
    ERIC DOMYAN; Fiscal Year: 2013
    ..by applicant): The development of epidermal appendages, such as hair in mammals and feathers and scales in birds, provides a particularly tractable model for studying medically-relevant processes such as fate determination, ..
  41. Transmission dynamics and spillover of avian influenza under changing agricultura
    Xiangming Xiao; Fiscal Year: 2013
    ..HPAI) subtype H5N1 persists in a number of countries in Asia and Africa, and continues to evolve in wild birds, domestic poultry and humans...
  42. Performance Error Signals in Basal Ganglia-Forebrain Circuits of the Songbird
    Michale S Fee; Fiscal Year: 2013
    ..pathway (AFP), a basal ganglia-forebrain circuit necessary for song learning, but not for singing in adult birds. In preliminary experiments, we have found that transient inactivation of the AFP output produces an immediate ..
  43. The Structure and Function of the Influenza Virus Genome
    Robert A Lamb; Fiscal Year: 2011
    ..continuing great concern today is the highly virulent avian H5N1 influenza virus that is still circulating among birds and transmitting to humans in parts of Far East Asia...
  44. EID - Effects of avian migration & anthropogenic change on the distribution & tra
    Thomas Smith; Fiscal Year: 2009
    ..Wild birds have also often been implicated in the spread of numerous zoonotic diseases leading to global pandemics...
  45. PERIPHERAL MECHANISMS OF HEARING
    Mario A Ruggero; Fiscal Year: 2013
    ..b>Birds, including pigeons, are more distantly related to humans, having evolved from dinosaurs...
  46. CELLULAR AND MOLECULAR BIOLOGY OF AGING
    Richard A Miller; Fiscal Year: 2013
    ..short-term primary fibroblast cells from a wide range of short-lived and long-lived rodents, primates, bats, birds, and dogs, and stimulate research at UM and elsewhere into cellular traits correlated with longevity across ..
  47. A Unique Natural Model for Studying the Mechanisms Underlying Social Behavior
    Donna L Maney; Fiscal Year: 2013
    ..have established that individuals with a white-stripe (WS) on the crown are more competitive and aggressive, and birds with a tan stripe (TS) engage in more parental care...
  48. Formation and Function of Circuitry for Vocal Learning
    Stephanie Ann White; Fiscal Year: 2013
    ..Area X FoxP2 levels are robust early in development, but when juvenile or adult birds practice their songs, FoxP2 is acutely down-regulated...
  49. AUDITORY MEMORIES AND VOCAL LEARNING
    Frederic E Theunissen; Fiscal Year: 2013
    ..We will also record neural activity in awake behaving birds using a miniaturized electrode drive...
  50. Southern Hemisphere Influenza and Vaccine Effectiveness Research and Surveillance
    Sue Huang; Fiscal Year: 2013
    ..ID) is cooperating with the WHO Collaborating Center for Studies on the Ecology of Influenza in Animals and Birds, and with New Zealand public health laboratories and Universities to conduct a five year study in the southern ..
  51. Mechanisms underlying asymmetric rotation and vascular development of the midgut
    Natasza A Kurpios; Fiscal Year: 2013
    ..In mice and birds, Pitx2 is necessary and sufficient to produce the leftward tilt, and this rotation is randomized in embryos ..
  52. UBIQUITIN AND CELLULAR FACTORS IN CORONAVIRUS ASSEMBLY
    THOMAS MILLER GALLAGHER; Fiscal Year: 2010
    Coronaviruses cause respiratory and gastrointestinal diseases in birds and animals. These RNA viruses are genetically variable and can rapidly evolve to infect humans, sometimes causing severe acute respiratory disease...
  53. Glycan receptors specific for canine influenza infection
    Xiu Feng Wan; Fiscal Year: 2013
    ..Human infection of animal origin influenza A viruses by contacting wild or farmed animals (e.g. birds or swine) has caused serious public concerns...
  54. In-ovo vaccination/avian influenza/bird/human
    DE CHU CHRISTOPHER TANG; Fiscal Year: 2010
    ..Vaccinating eggs before they hatch is much faster, easier, and less expensive than vaccinating live birds. The aim of this proposal is to develop a safe and effective vaccine which can rapidly vaccinate eggs to stop or ..
  55. Defining ATOH1 function and regulation in avian supporting cells
    Rebecca Lewis; Fiscal Year: 2013
    ..However, regeneration of hair cells readily occurs in birds, restoring hearing function...
  56. Sensorimotor control of the oropharynx and esophagus
    RODERICK ATKINS SUTHERS; Fiscal Year: 2013
    ..Parallels between the production of speech and birdsong have recently been strengthened by the discovery in birds of new song-related motor programs that modulate the dimensions of the supra glottal vocal tract, causing it to ..
  57. Molecular Interactions During Neural Crest Formation
    MARTIN IGNACIO GARCIA-CASTRO; Fiscal Year: 2013
    ..This work will illuminate fundamental principles of neural crest formation in higher vertebrates (birds and mammals), and will invigorate human neural crest studies.
  58. COORDINATION OF CIRCADIAN PHYSIOLOGY OF DIVERSE SPECIES
    Deborah Bell Pedersen; Fiscal Year: 2010
    ..The research instead revealed that all circadian systems, from cyanobacteria to mammals and birds: (1) comprise multiple circadian oscillations that behave independently under some experimental conditions and are ..
  59. Quasispecies dynamics in arbovirus persistence emergence and fitness
    GREGORY DAVID EBEL; Fiscal Year: 2013
    ..Virus will be passed in each of these birds and genetic diversity and fitness assessed...
  60. 6th International Symposium on the Biology of Vertebrate Sex Determination
    Richard R Behringer; Fiscal Year: 2012
    ..is attended by the entire international field working on diverse vertebrate systems including amphibians, fishes, birds, reptiles, monotremes, marsupials, and eutherian mammals, including domesticated species, mice, and humans...
  61. Determining the reservoir hosts for host-targeted control measures to prevent Lym
    MARIA ANA DIUK WASSER; Fiscal Year: 2010
    ..important in maintaining this pathogen is very limited, due to the logistical difficulty of studying mammals and birds in natural settings. This project will examine the variability in the composition of the B...
  62. Stimulation of retinal regeneration
    Thomas A Reh; Fiscal Year: 2013
    ..Regeneration is considerably more limited in birds and rodents, both in quantity and types of neurons generated...
  63. MECHANISMS OF NEUROPATHOGENESIS IN BORNA DISEASE
    Mady Hornig; Fiscal Year: 2002
    ..Natural infection has been confirmed only in horses, sheep, cattle, birds, and cats; however, primates can be infected experimentally...
  64. CELLULAR MECHANISMS OF THE VESTIBULAR SYSTEM
    Jay Goldberg; Fiscal Year: 2009
    ..on the type I hair cell and its calyx ending, phylogenetically recent acquisitions, only found in reptiles, birds and mammals. These structures are restricted to central/striolar zones In reptiles and birds...
  65. ENVIRONMENTAL SEX DETERMINATION AND DIFFERENTIATION
    David Crews; Fiscal Year: 1991
    Mammals, birds, and reptiles constitute the amniote vertebrates. In all mammals and birds, and in many reptiles, sex is determined at fertilization by genotype (genotypic sex determination or GSD)...
  66. PATHOGENIC/IMMUNOGENIC/STUDIES/CRYPTOSPORIDIUM GENOTYPES
    Abhineet Sheoran; Fiscal Year: 2006
    ..C. meleagridis (which infects birds and mammals) has also been associated with human cryptosporidiosis recently. C...
  67. Cochlear Therapy through Magnetic Targeted Drug Delivery
    Richard Kopke; Fiscal Year: 2009
    ..When hair cells die, spiral ganglion neurons also may lose their peripheral axons and degenerate. In birds, but not mammals, supporting cells re-enter the cell cycle, divide and differentiate into new hair cells...
  68. Emergence and adaption of West Nile virus in New York
    Laura Kramer; Fiscal Year: 2006
    ..The virus was first identified in the Western Hemisphere in 1999 when humans, mosquitoes, birds and horses in a limited area near New York City were found infected...
  69. High frequency auditory sensitivity in birds
    Bernard Lohr; Fiscal Year: 2004
    ..this research is to advance the understanding of the limitations, diversity, and comparative aspects of hearing in birds. The study of avian auditory sensitivity has provided a number of insights into the more general mechanisms of ..
  70. ALTERNATIVE ROLES FOR PHOSPHOENOLPYRUVATE CARBOXYKINASE
    Paul Ray; Fiscal Year: 1991
    ..The hepatic cellular distribution of PEPCK varies with species: mitochondrial(M) in birds, cytoplasmic(C) in rodents and both M and C in other species. M and C activities are due to different isozymes...
  71. GENE CONVERSION IN MYC INDUCED BURSAL LYMPHOMAS
    Craig Thompson; Fiscal Year: 2001
    ..period with avian leukosis (ALV), a retrovirus that does not contain a known transforming segment, 50-70% of birds in susceptible strains develop B cell lymphomas by 5-6 months of age...
  72. Effects of Acoustic Trauma on Age-Related Hearing Loss
    Dianne Durham; Fiscal Year: 2002
    ..Broiler birds raised commercially for meat production show a substantial progressive age-related cochlear degeneration beginning ..
  73. DEVELOPMENT OF SOUND LOCALIZATION
    Catherine Carr; Fiscal Year: 2000
    ..Mechanisms of time coding may be particularly accessible in the bird's auditory brainstem. In birds, auditory nerve fibers enter the brain and divide to terminate in the cochlear nucleus angularis and the cochlear ..
  74. VENUE OF AMPLIFICATION OF EEE OUTBREAKS
    Andrew Spielman; Fiscal Year: 2004
    ..This proposal aims to determine whether outbreaks of eastern equine encephalitis virus (EEEV) develop mainly among birds that attain high local abundance, are faithful to particular roost sites, are probed repeatedly by vector ..
  75. MOLECULAR NEUROBIOLOGY OF THE CIRCADIAN CLOCK
    Vincent Cassone; Fiscal Year: 2000
    ..In birds, melatonin plays a particularly critical role...