laboratory animals

Summary

Top Publications

  1. ncbi Species-specific assessment of pain in laboratory animals
    Karen L Stasiak
    Department of Pathology, Veterinary Teaching Hospital, Colorado State University, Fort Collins, CO 80523 1682, USA
    Contemp Top Lab Anim Sci 42:13-20. 2003
  2. ncbi Modifications to husbandry and housing conditions of laboratory rodents for improved well-being
    Abigail L Smith
    School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA
    ILAR J 46:140-7. 2005
  3. ncbi Cardiac troponin I is a sensitive, specific biomarker of cardiac injury in laboratory animals
    P J O'Brien
    Safety Sciences Europe, Sandwich, Kent CT1 3NJ, UK
    Lab Anim 40:153-71. 2006
  4. ncbi Establishing an appropriate period of acclimatization following transportation of laboratory animals
    Jennifer A Obernier
    Institute for Laboratory Animal Research, The National Academies, Washington, DC, USA
    ILAR J 47:364-9. 2006
  5. ncbi Guidelines for the design and statistical analysis of experiments using laboratory animals
    Michael F W Festing
    MRC Toxicology Unit, University of Leicester, UK
    ILAR J 43:244-58. 2002
  6. ncbi Laboratory animals: the Renaissance rat
    Alison Abbott
    Nature 428:464-6. 2004
  7. pmc Hearing in laboratory animals: strain differences and nonauditory effects of noise
    Jeremy G Turner
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, Illinois 62794 9629, USA
    Comp Med 55:12-23. 2005
  8. ncbi An inclined plane system with microcontroller to determine limb motor function of laboratory animals
    Ming Wen Chang
    Department of Electrical Engineering, National Cheng Kung University, Tainan 701, Taiwan
    J Neurosci Methods 168:186-94. 2008
  9. ncbi Spatial and temporal patterns of expression of messenger RNA for insulin-like growth factors and their binding proteins in the placenta of man and laboratory animals
    V K Han
    Department of Paediatrics, Obstetrics and Gynaecology, Biochemistry and Anatomy, MRC Group in Fetal and Neonatal Health and Development, Lawson Research Institute, University of Western Ontario, London, Ontario, N6A 4V2, Canada
    Placenta 21:289-305. 2000
  10. ncbi A comparative immunohistochemical study of pancreatic islets in laboratory animals (rats, dogs, minipigs, nonhuman primates)
    G Wieczorek
    Experimental Pathology, Novartis Pharma AG, Basel, Switzerland
    Exp Toxicol Pathol 50:151-72. 1998

Research Grants

  1. Study of Genetics, Endotoxin and Allergen (SAGE)
    Karin Pacheco; Fiscal Year: 2007
  2. A Novel Detector for Combined Optical and PET Imaging
    Arion Chatziioannou; Fiscal Year: 2007
  3. IBANGS Annual Meeting support
    John Crabbe; Fiscal Year: 2005
  4. Genetics of Longevity and Age-Sensitive Traits in Mice
    Richard Miller; Fiscal Year: 2008
  5. Identity and Function of CNS Progenitor Cell Genes
    Harley Kornblum; Fiscal Year: 2007
  6. Methamphetamine, Stress and SIV: Effects at Blood-Brain Barrier and Lymph Nodes
    John P Capitanio; Fiscal Year: 2010
  7. POSITRON TOMOGRAPHY IN ISCHEMIC HEART DISEASE
    Heinrich Schelbert; Fiscal Year: 2004
  8. WILD DERIVED MOUSE STOCKS--NEW MODELS FOR AGING RESEARCH
    Richard Miller; Fiscal Year: 2004
  9. METABOLISM OF CARCINOGENIC TOBACCO SPECIFIC NITROSAMINES
    Stephen Hecht; Fiscal Year: 2003
  10. THE ECONOMICS OF POLYDRUG ABUSE
    RICHARD MEISCH; Fiscal Year: 2001

Detail Information

Publications200 found, 100 shown here

  1. ncbi Species-specific assessment of pain in laboratory animals
    Karen L Stasiak
    Department of Pathology, Veterinary Teaching Hospital, Colorado State University, Fort Collins, CO 80523 1682, USA
    Contemp Top Lab Anim Sci 42:13-20. 2003
    ....
  2. ncbi Modifications to husbandry and housing conditions of laboratory rodents for improved well-being
    Abigail L Smith
    School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA
    ILAR J 46:140-7. 2005
    ..Also suggested are possible inexpensive and effective enrichment schemes for laboratory mice that might include reducing the cage floor space per mouse combined with providing nesting material...
  3. ncbi Cardiac troponin I is a sensitive, specific biomarker of cardiac injury in laboratory animals
    P J O'Brien
    Safety Sciences Europe, Sandwich, Kent CT1 3NJ, UK
    Lab Anim 40:153-71. 2006
    ..directly demonstrates that cardiac troponin I (cTnI) is a sensitive, specific, and persistent biomarker in laboratory animals. Histopathological and pathophysiological cardiac changes in dogs, rats and mice correlated with increased ..
  4. ncbi Establishing an appropriate period of acclimatization following transportation of laboratory animals
    Jennifer A Obernier
    Institute for Laboratory Animal Research, The National Academies, Washington, DC, USA
    ILAR J 47:364-9. 2006
    Stress associated with transportation has widespread effects on physiological systems in laboratory animals, including changes in the cardiovascular, endocrine, immune, central nervous, and reproductive systems...
  5. ncbi Guidelines for the design and statistical analysis of experiments using laboratory animals
    Michael F W Festing
    MRC Toxicology Unit, University of Leicester, UK
    ILAR J 43:244-58. 2002
    ....
  6. ncbi Laboratory animals: the Renaissance rat
    Alison Abbott
    Nature 428:464-6. 2004
  7. pmc Hearing in laboratory animals: strain differences and nonauditory effects of noise
    Jeremy G Turner
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, Illinois 62794 9629, USA
    Comp Med 55:12-23. 2005
    Hearing in laboratory animals is a topic that traditionally has been the domain of the auditory researcher...
  8. ncbi An inclined plane system with microcontroller to determine limb motor function of laboratory animals
    Ming Wen Chang
    Department of Electrical Engineering, National Cheng Kung University, Tainan 701, Taiwan
    J Neurosci Methods 168:186-94. 2008
    ..It is found that the system is stable, accurate and easily used by investigators...
  9. ncbi Spatial and temporal patterns of expression of messenger RNA for insulin-like growth factors and their binding proteins in the placenta of man and laboratory animals
    V K Han
    Department of Paediatrics, Obstetrics and Gynaecology, Biochemistry and Anatomy, MRC Group in Fetal and Neonatal Health and Development, Lawson Research Institute, University of Western Ontario, London, Ontario, N6A 4V2, Canada
    Placenta 21:289-305. 2000
    ..to date highlight the diversity in the expression of the IGF system among placentae of man and different laboratory animals, and even between closely related species...
  10. ncbi A comparative immunohistochemical study of pancreatic islets in laboratory animals (rats, dogs, minipigs, nonhuman primates)
    G Wieczorek
    Experimental Pathology, Novartis Pharma AG, Basel, Switzerland
    Exp Toxicol Pathol 50:151-72. 1998
    ..and describe the patterns of distribution of pancreatic islets within the pancreas of four species of laboratory animals, including rats, dogs, minipigs and monkeys, and furthermore, to identify immunohistochemically various ..
  11. ncbi Defining, measuring, and interpreting stress in laboratory animals
    Cynthia Pekow
    Veterinary Medical Unit, Research 151 L, Veterans Affairs Puget Sound Health Care System, 1660 South Columbian Way, Seattle, Washington 98108, USA
    Contemp Top Lab Anim Sci 44:41-5. 2005
    ..However, stress is not inherently bad, and a stress response should not be assumed to indicate an experience of distress or pain. This paper examines ways in which research animal stress may be defined, measured, and interpreted...
  12. ncbi Virucidal efficacy of physico-chemical treatments against coronaviruses and parvoviruses of laboratory animals
    M Saknimit
    Laboratory Animal Research Center, University of Tsukuba, Ibaraki, Japan
    Jikken Dobutsu 37:341-5. 1988
    ..Ultraviolet radiation inactivated all viruses within 15 minutes. No significant differences in stability against physico-chemical treatments were seen between viruses in the same group...
  13. pmc Incidence of allergy and allergy symptoms among workers exposed to laboratory animals
    L Elliott
    Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599 7435, USA
    Occup Environ Med 62:766-71. 2005
    Few studies have described relations between exposure to laboratory animals and the incidence of laboratory animal allergy (LAA)...
  14. ncbi [Prevalence of occupational allergy to laboratory animals in two towns of northern and central Italy]
    F Larese Filon
    Dipartimento di Scienze di Medicina Pubblica, Universita degli Studi di Trieste, Via della Pieta 19, 34129 Trieste
    Med Lav 93:87-94. 2002
    ..Laboratory animal allergy (LAA) is a well known occupational hazard for workers employed in biological and medical research institutes, but few Italian data on this disease exist...
  15. ncbi Review of growth plate closure compared with age at sexual maturity and lifespan in laboratory animals
    Susan H Kilborn
    Animal Care and Veterinary Service, Department of Medicine, University of Ottawa, Ontario, Canada K1H 8M5
    Contemp Top Lab Anim Sci 41:21-6. 2002
    ..The rat was compared to other laboratory animals to assess differences in the duration of bone growth and its relationship to age at sexual maturity and ..
  16. ncbi An updated review of inhalation studies with cigarette smoke in laboratory animals
    Christopher R E Coggins
    Carson Watts Consulting, 1266 CarsonWatts Road, King, North Carolina 27021 7453, USA
    Int J Toxicol 26:331-8. 2007
    Until recently, the published literature on inhalation studies with laboratory animals and cigarette smoke consisted entirely of negative findings, as far as neoplastic disease is concerned...
  17. ncbi Factors affecting hearing in mice, rats, and other laboratory animals
    James F Willott
    University of South Florida, Tampa, FL, USA
    J Am Assoc Lab Anim Sci 46:23-7. 2007
    ..An understanding of genetic and environmental influences on hearing and auditory behavior is important for those who provide, use, and care for laboratory animals.
  18. ncbi [Laboratory animals and official Mexican norms (NOM-062-ZOO-1999)]
    Aline S de Aluja
    Departamento de Patologia, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autonoma de Mexico, Circuito exterior s n, Ciudad Universitaria, CP 04510 Mexico, D F
    Gac Med Mex 138:295-8. 2002
    ..Mexican norm Nom 0062-Zoo-1999 entitled Technical specifications for the production, care and use of laboratory animals. The history of animal experimentation is briefly resumed...
  19. ncbi [Microbiological standardization of laboratory animals]
    W Nicklas
    Deutsches Krebsforschungszentrum, Zentrales Tierlabor
    Berl Munch Tierarztl Wochenschr 112:201-10. 1999
    An overview is given on various aspects of microbiological standardisation of laboratory animals. The paper focuses on small rodents because rats and mice are the most frequently used animal species...
  20. ncbi Design, construction, and characterization of a novel robotic welding fume generator and inhalation exposure system for laboratory animals
    James M Antonini
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
    J Occup Environ Hyg 3:194-203; quiz D45. 2006
    ....
  21. ncbi RandoMate: a program for the generation of random mating schemes for small laboratory animals
    Armin O Schmitt
    Institute for Animal Sciences, Humboldt Universitat zu Berlin, Berlin, Germany
    Mamm Genome 20:321-5. 2009
    ..RandoMate is freely available at http://www2.hu-berlin.de/RandoMate ...
  22. ncbi Wallace P. Rowe lecture. Poxviruses of laboratory animals
    F Fenner
    John Curtin School of Medical Research, Australian National University
    Lab Anim Sci 40:469-80. 1990
    ..The list could have been extended had I included chickens and swine as laboratory animals, for that would have meant that I would have spoken about the birdpox viruses and swinepox virus as well...
  23. ncbi Natural pathogens of laboratory animals and their effects on research
    M D Connole
    Department of Veterinary Pathology and Anatomy, School of Veterinary Science, The University of Queensland, Brisbane, Australia
    Med Mycol 38:59-65. 2000
    The natural fungal pathogens of laboratory animals such as rabbits and guinea pigs are mainly dermatophyte species, most commonly Trichophyton mentagrophytes and also, less frequently Microsporum gypseum and M. canis...
  24. ncbi Enrichment strategies for laboratory animals from the viewpoint of clinical veterinary behavioral medicine: emphasis on cats on dogs
    Karen L Overall
    Center for Neurobiology and Behavior Psychiatry Department, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    ILAR J 46:202-15. 2005
    Behavioral wellness has become a recent focus for the care of laboratory animals, farm and zoo animals, and pets. Behavioral enrichment issues for these groups are more similar than dissimilar, and each group can learn from the other...
  25. ncbi Primary and secondary allergies to laboratory animals
    Leslie E Goodno
    Department of Epidemiology, CB 7435 McGavran Greenberg Hall, UNC School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7435, USA
    J Occup Environ Med 44:1143-52. 2002
    Although laboratory animal allergy (LAA) is a significant occupational hazard among workers exposed to laboratory animals, few studies have evaluated long-term risks to workers who remain in the workplace...
  26. ncbi Potential for unintended consequences of environmental enrichment for laboratory animals and research results
    Kathryn Bayne
    AAALAC International, Hilo, HI, USA
    ILAR J 46:129-39. 2005
    ....
  27. ncbi Immunogenicity of biopharmaceuticals in laboratory animals
    D Wierda
    Toxicology Division, Lilly Research Laboratories, Eli Lilly and Company, 2001 W Main Street, GL45, Greenfield, IN 46140, USA
    Toxicology 158:71-4. 2001
    ..In addition, the characterization of the immunogenicity of biotechnology molecules provides a practical basis for determining the significance of antibody formation in preclinical safety studies...
  28. ncbi Recognizing and assessing pain, suffering and distress in laboratory animals: a survey of current practice in the UK with recommendations
    Penny Hawkins
    Research Animals Department, RSPCA, Wilberforce Way, Southwater, West Sussex, RH13 9RS, UK
    Lab Anim 36:378-95. 2002
    ..org.uk/pain/(Hawkins 2002). The present paper and the full report, including its recommendations, are intended to provide a source of information, discussion topics and ideas for all establishments that need to monitor animal well-being...
  29. ncbi Hearing ranges of laboratory animals
    Henry E Heffner
    Department of Psychology, University of Toledo, Toledo, OH, USA
    J Am Assoc Lab Anim Sci 46:20-2. 2007
    ..As a result, a sound that is easily audible to one species may be less audible, or even inaudible, to another. The purpose of this review is to describe the variation in the hearing ranges of common laboratory animals.
  30. ncbi Carcinogenicity studies of inhaled cigarette smoke in laboratory animals: old and new
    Stephen S Hecht
    The Cancer Center, University of Minnesota, Mayo Mail Code 806, 420 Delaware Street, SE, Minneapolis, MN 55455, USA
    Carcinogenesis 26:1488-92. 2005
    ..This commentary attempts to put the new results in perspective with the existing literature on cigarette smoke inhalation studies in animals and discusses strengths, limitations and possible applications of available models...
  31. ncbi Evaluation and applications of radiotelemetry in small laboratory animals
    Klaas Kramer
    Department of Safety and Environmental Affairs, Free University, DVM, 1081 BT Amsterdam, The Netherlands
    Physiol Genomics 13:197-205. 2003
    Radiotelemetry is the "state of the art" for monitoring physiological functions in awake and freely moving laboratory animals, while minimizing stress artifacts...
  32. ncbi Phytochemical screening and effect of aqueous extract of Ficus sycomorus L. (Moraceae) stem bark on muscular activity in laboratory animals
    U K Sandabe
    Department of Veterinary Physiology and Pharmacology, University of Maiduguri, P M B 1069, Maiduguri, Nigeria
    J Ethnopharmacol 104:283-5. 2006
    ..It was concluded that the extract has inhibitory effect on both smooth and skeletal muscles contractions and contains important constituents for pharmacological activities...
  33. ncbi Association of Toll-like receptor 4 alleles with symptoms and sensitization to laboratory animals
    Karin Pacheco
    Division of Environmental and Occupational Health Sciences, Department of Medicine, National Jewish Medical and Research Center, Denver, CO 80206, USA
    J Allergy Clin Immunol 122:896-902.e4. 2008
    Researchers and technicians working with laboratory animals (LAs) are exposed to animal allergen and endotoxin, which can interact to potentiate or inhibit symptoms or allergic responses...
  34. ncbi Guidance on the transport of laboratory animals
    Jeremy Swallow
    Pfizer Global Research and Development, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK
    Lab Anim 39:1-39. 2005
  35. ncbi Reference data for the principal physiological indicators in three species of laboratory animals
    C L Alemán
    Departamento de Toxicologia, Centro de Productos Naturales, Centro Nacional de Investigaciones Cientificas, La Habana, Cuba
    Lab Anim 34:379-85. 2000
    This paper contains the reference data for the main physiological indicators of three species of laboratory animals: mice, rabbits and dogs...
  36. ncbi An event-driven motion correction method for neurological PET studies of awake laboratory animals
    Victor W Zhou
    School of Physics, University of Sydney, NSW 2006, Sydney, Australia
    Mol Imaging Biol 10:315-24. 2008
    The purpose of the study is to investigate the feasibility of an event driven motion correction method for neurological microPET imaging of small laboratory animals in the fully awake state.
  37. ncbi Natural history of sensitization, symptoms and occupational diseases in apprentices exposed to laboratory animals
    D Gautrin
    Dept of Chest Medicine, , Montreal, Canada
    Eur Respir J 17:904-8. 2001
    ..and asthma (OA); and assesses the predictive value of skin testing and RC symptoms in apprentices exposed to laboratory animals, in a 3-4-yr programme...
  38. ncbi The use of radiotelemetry in small laboratory animals: recent advances
    K Kramer
    Department of Safety and Environmental Affairs, Free University, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
    Contemp Top Lab Anim Sci 40:8-16. 2001
    ..provides an alternative means of obtaining physiological measurements from awake and freely moving laboratory animals, without introducing stress artifacts...
  39. ncbi Pathology and pathophysiology of drug-induced arterial injury in laboratory animals and its implications on the evaluation of novel chemical entities for human clinical trials
    C Louden
    Department of Safety Assessment, SmithKline Beechman Pharmaceuticals, King of Prussia, PA 19403, USA
    Pharmacol Toxicol 89:158-70. 2001
    In toxicology studies, drug-induced arterial injury in laboratory animals continues to be a pressing issue of concern, particularly to those engaged in the discovery and development of novel therapies intended for human use...
  40. ncbi Investigating the dopaminergic synapse in vivo. II. Molecular imaging studies in small laboratory animals
    Susanne Nikolaus
    Clinic of Nuclear Medicine, University Hospital Dusseldorf, Germany
    Rev Neurosci 18:473-504. 2007
    ..Therefore, small laboratory animals such as rats and mice have become invaluable models for a variety of human disorders...
  41. ncbi Guidelines for the veterinary care of laboratory animals: report of the FELASA/ECLAM/ESLAV Joint Working Group on Veterinary Care
    Hanna Marja Voipio
    Laboratory Animal Centre, PO Box 5000, FIN 90014 University of Oulu, Finland
    Lab Anim 42:1-11. 2008
    ..Managerial aspects, including occupational health and safety, are also areas where the veterinarian's input can assist in the successful implementation of the programme...
  42. ncbi Incidence and host determinants of probable occupational asthma in apprentices exposed to laboratory animals
    D Gautrin
    Department of Chest Medicine, Hôpital du Sacré Coeur, Montreal, Quebec, Canada
    Am J Respir Crit Care Med 163:899-904. 2001
    ..43 to 0.78). It is concluded that apprentices in animal health show a high incidence of probable OA, and that preexposure airway caliber and responsiveness as well as sensitization to pets are associated with an increased risk...
  43. ncbi Mandatory " enriched" housing of laboratory animals: the need for evidence-based evaluation
    Ann C Benefiel
    Beckman Institute, University of Illinois, Urbana Campaign, IL, USA
    ILAR J 46:95-105. 2005
    Environmental enrichment for laboratory animals has come to be viewed as a potential method for improving animal well-being in addition to its original sense as a paradigm for learning how experience molds the brain...
  44. ncbi A survey of rodent-borne pathogens carried by wild-caught Norway rats: a potential threat to laboratory rodent colonies
    Judith D Easterbrook
    The W Harry Feinstone Department of Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lab Anim 42:92-8. 2008
    ..8%), were identified in wild-caught rats. The risk of pathogen transmission from wild-caught rats to laboratory colonies needs to be mitigated by minimizing exposures rather than assuming wild animals represent a minimal hazard...
  45. ncbi Science-based assessment of animal welfare: laboratory animals
    V Baumans
    Division of Laboratory Animal Science, Utrecht University, P O Box 80 166, 3508 TD Utrecht, the Netherlands Karolinska Institute, 17177 Stockholm, Sweden
    Rev Sci Tech 24:503-13. 2005
    ..In this paper, attention is paid to the assessment of welfare, environmental factors affecting welfare, legislative requirements and future trends such as the production and use of genetically modified animals...
  46. ncbi Genetically modified laboratory animals--what welfare problems do they face?
    Mia Buehr
    Center for Bioethics and Risk Assessment, Department of Molecular Biology, University of Aarhus, Denmark
    J Appl Anim Welf Sci 6:319-38. 2003
    ..In this article, we also consider suffering that may be involved in the process of generating GM animals. Finally, we discuss the role of GM animals in attempts to reduce, replace, and refine the use of animals in research...
  47. ncbi Host determinants for the development of allergy in apprentices exposed to laboratory animals
    D Gautrin
    Dept of Chest Medicine, Hôpital du Sacré Coeur, Montreal, Canada
    Eur Respir J 19:96-103. 2002
    ..sensitization and diseases differ between atopic and nonatopic subjects starting a career with exposure to laboratory animals (LA)...
  48. ncbi Frequency of allergic rhinitis to laboratory animals in university employees as confirmed by chamber challenges
    P Ruoppi
    Department of Otorhinolaryngology, Kuopio University Hospital, Kuopio, Finland
    Allergy 59:295-301. 2004
    ..Occupational risk for laboratory animal allergy (LAA) is well known, but prevention is often insufficient and new cases keep appearing...
  49. ncbi Experimental infection of laboratory animals and sheep with Gongylonema pulchrum in Japan
    Noboru Kudo
    School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan
    J Vet Med Sci 65:921-5. 2003
    ..No distinct morphological differences were observed in the worms from rabbits and sheep. These results indicate that rabbits are very suitable experimental definitive hosts for G. pulchrum...
  50. pmc A fully implantable stimulator for use in small laboratory animals
    Rodney E Millard
    Department of Otolaryngology, University of Melbourne, East Melbourne, Victoria 3002, Australia
    J Neurosci Methods 166:168-77. 2007
    ..which are delivered to a bipolar electrode array for chronic stimulation of neural tissue in free-running laboratory animals such as rats and mice. The system is magnetically coupled and contains no batteries or external leadwires...
  51. ncbi Interspecies transmission of Enterozytozoon bieneusi supported by observations in laboratory animals and phylogeny
    C Drosten
    Medical Microbiology Section, Bernhard Nocht Insitute for Tropical Medicine, Bernhard Nocht Str 74, 20359 Hamburg, Germany
    Med Microbiol Immunol 194:207-9. 2005
    ..Zoonotic potential of E. bieneusi is thus supported on a phylogenetic basis...
  52. ncbi Measuring blood pressure in small laboratory animals
    Klaas Kramer
    Department of Safety and Environmental Affairs DVM, Free University, Amsterdam, The Netherlands
    Methods Mol Med 108:51-62. 2005
    ..This chapter describes the surgical aspects of the radiotelemetry techniques currently used to monitor and measure blood pressure in awake animals...
  53. ncbi Nasal lavage fluid examination and rhinomanometry in the diagnostics of occupational airway allergy to laboratory animals
    Anna Krakowiak
    Department of Occupational Diseases, Nofer Institute of Occupational Medicine, Lodz, Poland
    Int J Occup Med Environ Health 16:125-32. 2003
    ....
  54. ncbi The use of lignocaine-prilocaine local anaesthetic cream for pain-free venepuncture in laboratory animals
    P A Flecknell
    Comparative Biology Centre, Medical School, Newcastle upon Tyne, UK
    Lab Anim 24:142-6. 1990
    ..of topical application of a eutectic mixture of local anaesthetics (EMLA cream) in a number of species of laboratory animals. Application of EMLA cream enabled percutaneous insertion of catheters into the cephalic vein in dogs and ..
  55. ncbi Have the prevalence and incidence of occupational asthma and rhinitis because of laboratory animals declined in the last 25 years?
    I Folletti
    Occupational Allergology, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Allergy 63:834-41. 2008
    ..Data for time trends in the prevalence of occupational asthma (OA) and rhinitis (OR) are not known...
  56. ncbi A novel type of implantable and programmable infusion pump for small laboratory animals
    Chikara Abe
    Department of Physiology, Gifu University Graduate School of Medicine, Gifu, Japan
    J Pharmacol Toxicol Methods 59:7-12. 2009
    The iPRECIO (Primetech Corporation, Tokyo, Japan) is a new form of pump for infusing small laboratory animals. The key features of the iPRECIO are that it can be implanted within the animal, it is refillable, and it is programmable...
  57. ncbi Japanese macaques as laboratory animals
    Tadashi Isa
    Section for NBR Promotion, National Institute for Physiological Sciences, Myodaiji, Okazaki, Japan
    Exp Anim 58:451-7. 2009
    ..The project is in progress and should lead to the establishment of a National Primate Center in Japan, which will support the supply of monkeys as well as social outreach and handling of animal welfare issues...
  58. pmc Molecular characterization of pneumococcal isolates from pets and laboratory animals
    Mark van der Linden
    Department of Medical Microbiology, National Reference Center for Streptococci, University Hospital RWTH, Aachen, Germany
    PLoS ONE 4:e8286. 2009
    ..dolphins (n = 2), rat (n = 2), gorilla (n = 1)) treated in medical veterinary laboratories and zoos, and 44 laboratory animals (mastomys (multimammate mice; n = 32), mice (n = 6), rats (n = 4), guinea pigs (n = 2)) during routine ..
  59. pmc Comparable measures of cognitive function in human infants and laboratory animals to identify environmental health risks to children
    Carolyn Sharbaugh
    Westat, Rockville, Maryland, USA
    Environ Health Perspect 111:1630-9. 2003
    ..examining measures of cognitive function that can be applied to both human infants (0-12 months old) and laboratory animals. We begin with a discussion of the definition of cognitive function and important considerations in cross-..
  60. ncbi Laboratory animal welfare: cage enrichment and mouse behaviour
    David P Wolfer
    Division of Neuroanatomy and Behaviour, Institute of Anatomy, University of Zurich, 8057 Zurich, Switzerland
    Nature 432:821-2. 2004
    ..Our findings indicate that the housing conditions of laboratory mice can be markedly improved without affecting the standardization of results...
  61. ncbi Scientific procedures on living animals in Great Britain in 2003: the facts, figures and consequences
    Michelle Hudson
    FRAME, Russell and Burch House, 96 98 North Sherwood Street, Nottingham NG1 4EE, UK
    Altern Lab Anim 32:473-85. 2004
    ..The implications of these latest statistics are discussed with reference to key areas of interest and to the impact of existing regulations and pending legislative reforms...
  62. ncbi To enrich or not to enrich: providing shelter does not complicate handling of laboratory mice
    Christel P H Moons
    Animal Nutrition, Genetics, Breeding and Ethology, Faculty of Veterinary Medicine, Ghent University, Belgium
    Contemp Top Lab Anim Sci 43:18-21. 2004
    ..does not complicate catching or handling mice and that allowing access to enrichment in the laboratory cage, which has been shown to have positive effects on welfare, does not interfere with the management or cost of laboratory animals.
  63. ncbi Assessment of the use of two commercially available environmental enrichments by laboratory mice by preference testing
    Pascalle L P Van Loo
    Department of Laboratory Animal Science, Utrecht University, The Netherlands
    Lab Anim 39:58-67. 2005
    In the field of biomedical research, the demand for standardization of environmental enrichment for laboratory animals is growing. For laboratory mice, a wide variety of environmental enrichment items are commercially available...
  64. ncbi Environmental enrichment options for laboratory rats and mice
    David Key
    National Institute for Medical Research, Medical Research Council, The Ridgeway, Mill Hill, London NW7 1AA
    Lab Anim (NY) 33:39-44. 2004
  65. ncbi Environmental enrichment: room for reduction?
    Heleen A Van de Weerd
    Department of Laboratory Animal Science, Faculty of Veterinary Medicine, Utrecht University, P O Box 80 166, 3508 TD Utrecht, The Netherlands
    Altern Lab Anim 32:69-71. 2004
    ....
  66. ncbi Effects of an individually ventilated cage system on the airway integrity of rats (Rattus norvegicus) in a laboratory in Brazil
    M A Teixeira
    Centro de Ciencias Biologicas e da Saude, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil
    Lab Anim 40:419-31. 2006
    ....
  67. ncbi Husbandry refinements for rats, mice, dogs and non-human primates used in telemetry procedures. Seventh report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement, Part B
    Penny Hawkins
    Research Animals Department, RSPCA, Wilberforce Way, Southwater, West Sussex, RH13 9RS, UK
    Lab Anim 38:1-10. 2004
  68. ncbi Issues to consider for preparing ferrets as research subjects in the laboratory
    Roberta Scipioni Ball
    Department of Animal Health, Marshall BioResources, North Rose, NY, USA
    ILAR J 47:348-57. 2006
    ..Ferrets have a distinct niche in biomedical research and are hardy animals that thrive well in the laboratory...
  69. ncbi A renewed look at laboratory rodent housing and management
    Janet C Gonder
    Garber Consulting LLC, Pinehurst, NC, USA
    ILAR J 48:29-36. 2007
    Since its publication in 1996, the Guide for the Care and Use of Laboratory Animals (National Research Council, Washington DC, National Academy Press) has become a primary source of information for institutional animal care and use ..
  70. ncbi Survey of environmental enhancement programs for laboratory primates
    Kate C Baker
    Division of Veterinary Medicine, Tulane National Primate Research Center, Covington, Louisiana 70433, USA
    Am J Primatol 69:377-94. 2007
    ..The data from this survey may be useful for anticipating future program evaluations, establishing more effective internal evaluations, and assessing program progress and resource allocation...
  71. ncbi Reflecting on refinement
    Julia Schulhof
    Lab Anim (NY) 31:9. 2002
  72. doi Animal health assurance
    John Donovan
    BioResources Consulting, Wayne, Pennsylvania, USA
    Curr Protoc Neurosci . 2002
    A program to assure the health of laboratory animals and to provide a stable environment for their maintenance is necessary to reduce unwanted variables or complicating factors in experimentation...
  73. ncbi Training nonhuman primates to cooperate with scientific procedures in applied biomedical research
    Leah Scott
    Biomedical Sciences, Dstl Porton Down, Salisbury, Wiltshire, England
    J Appl Anim Welf Sci 6:199-207. 2003
    ..The importance of discussion and consideration of alternative procedures cannot be overemphasized...
  74. ncbi Introduction: environmental enrichment
    Thomas L Wolfle
    Institute for Laboratory Animal Research, Washington, DC, USA
    ILAR J 46:79-82. 2005
  75. ncbi USDA perspective on environmental enrichment for animals
    Jodie A Kulpa-Eddy
    United States Department of Agriculture, Animal and Plant Health Inspection Service, Riverdale, MD, USA
    ILAR J 46:83-94. 2005
    ....
  76. ncbi Considerations in the selection and conditioning of Old World monkeys for laboratory research: animals from domestic sources
    John P Capitanio
    California National Primate Research Center, University of California, Davis, CA, USA
    ILAR J 47:294-306. 2006
    ..Attention to issues of animal selection and conditioning by both researchers and colony managers can lead to the shared goal of high-quality research that utilizes the minimal number of animals...
  77. ncbi Laboratory environments and rodents' behavioural needs: a review
    J P Balcombe
    Physicians Committee for Responsible Medicine, 5100 Wisconsin Avenue, NW, Suite 400, Washington, DC 20016, USA
    Lab Anim 40:217-35. 2006
    ..Adding environmental 'enrichments' to small cages reduces but does not eliminate these problems, and I argue that substantial changes in housing and husbandry conditions would be needed to further reduce them...
  78. ncbi Management of unanticipated outcomes in transgenic mouse facilities
    Stacy Pritt
    Covance Research Products, Inc, Denver, PA 17517, USA
    Lab Anim (NY) 35:27-30. 2006
    ....
  79. ncbi Selection, acclimation, training, and preparation of dogs for the research setting
    LaVonne D Meunier
    Department of Laboratory Animal Science, GlaxoSmithKline Pharmaceuticals, King of Prussia, PA, USA
    ILAR J 47:326-47. 2006
    ..Canine socialization and training programs provided by skilled personnel, together with comprehensive veterinary health programs, can further enhance animal welfare and minimize interanimal and group variability in studies...
  80. ncbi Behavioral assessment of intermittent wheel running and individual housing in mice in the laboratory
    Therese M Pham
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Appl Anim Welf Sci 8:157-73. 2005
    ..Intermittent withdrawal of individual housing affects the animals more than other commodities. Wheel running normalizes some effects of intermittent separation from the enriched, social home cage...
  81. ncbi Balancing animal well-being, cost, and employee health and safety in caging design and selection
    Terry Receveur
    Eli Lilly and Company, Indianapolis, Indiana, USA
    Contemp Top Lab Anim Sci 44:68-71. 2005
  82. ncbi Preparation of swine for the laboratory
    Alison C Smith
    Department of Comparative Medicine, Medical University of South Carolina, Charleston, SC, USA
    ILAR J 47:358-63. 2006
    ..This manuscript provides an overview of best practices that have been utilized in the authors' facility...
  83. ncbi Introduction to the 3Rs (refinement, reduction and replacement)
    Faisal Guhad
    Pfizer Animal Health, Vet Med R and D Pharmaceuticals Discovery, Sandwich, Kent, United Kingdom
    Contemp Top Lab Anim Sci 44:58-9. 2005
  84. ncbi Behavioral management of chimpanzees in biomedical research facilities: the state of the science
    Mollie A Bloomsmith
    Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA
    ILAR J 46:192-201. 2005
    ..The next challenge is to implement effectively and thoroughly the approaches that have been shown to be beneficial...
  85. ncbi Environmental enrichment for nonhuman primates: theory and application
    Corrine K Lutz
    Division of Behavioral Biology, New England Primate Research Center, Harvard Medical School, Southborough, MA, USA
    ILAR J 46:178-91. 2005
    ..Only social contact satisfies the goal of promoting a wide variety of species-typical activities while at the same time reducing or preventing the development of abnormal behavior...
  86. ncbi Environmental enrichment for laboratory rodents and rabbits: requirements of rodents, rabbits, and research
    Vera Baumans
    Karolinska Institutet, Stockholm, Sweden
    ILAR J 46:162-70. 2005
    ..However, housing systems for laboratory animals have often been designed on the basis of economic and ergonomic aspects...
  87. ncbi Environmental enrichment for laboratory rodents
    Eric Hutchinson
    Division of Veterinary Resources, Office of Research Services, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    ILAR J 46:148-61. 2005
    ..Survey data on current enrichment practices in a large multi-institutional organization are presented, and practical aspects requiring consideration when devising a rodent enrichment program are discussed...
  88. ncbi Balancing animal research with animal well-being: establishment of goals and harmonization of approaches
    James L Weed
    Division of Veterinary Resources, Office of Research Services, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    ILAR J 46:118-28. 2005
    ..Better documentation of environmental variables and their correlation with experimental results will promote critical knowledge about the relationships between an animal's environment, its well-being, and science...
  89. ncbi Stereotypies and other abnormal repetitive behaviors: potential impact on validity, reliability, and replicability of scientific outcomes
    Joseph P Garner
    Department of Animals Sciences, Purdue University, West Lafayette, IN, USA
    ILAR J 46:106-17. 2005
    ..Thus, ARBs in laboratory animals may compromise validity, reliability, and replicability, especially in behavioral experiments; and ..
  90. ncbi Preparation of animals for research--issues to consider for rodents and rabbits
    Laura A Conour
    Department of Veterinary Services, Charles River Laboratories Charles River, Wilmington, MA, USA
    ILAR J 47:283-93. 2006
    ..Stress and distress are placed in perspective as they relate to the preparation of laboratory animals for research.
  91. ncbi Activists seek personhood for animals
    R Scott Nolen
    J Am Vet Med Assoc 223:759-60. 2003
  92. ncbi Of mice and their environments
    John C Crabbe
    Science 299:1313-4. 2003
  93. ncbi The rehabilitation of captive baboons
    A Kessel
    Department of Laboratory Animal Medicine, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245-0549, USA
    J Med Primatol 30:71-80. 2001
    ..This study provides evidence that even behaviorally disturbed nonhuman primates can be successfully rehabilitated to live in social groups...
  94. ncbi Environmental enrichment of nonhuman primates, dogs and rabbits used in toxicology studies
    Kathryn A L Bayne
    AAALAC International, Rockville, Maryland 20842, USA
    Toxicol Pathol 31:132-7. 2003
    The increasing emphasis on the provision of environmental enrichment to laboratory animals, vis-à-vis the USDA Animal Welfare Regulations, the Guide for the Care and Use of Laboratory Animals (NRC 1996), and a potential forthcoming ..
  95. ncbi The impact of reduced frequency of cage changes on the health of mice housed in ventilated cages
    C K Reeb-Whitaker
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Lab Anim 35:58-73. 2001
    ..In conclusion, under the conditions of this study, cage changes once every 14 days and ventilation rates of 60 ACH provide optimum conditions for animal health and practical husbandry...
  96. ncbi Are "by-stander" female Sprague-Dawley rats affected by experimental procedures?
    Jody Sharp
    Department of Physiology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Contemp Top Lab Anim Sci 42:19-27. 2003
    ..Finally, group housing often, but not always, reduces the stress-like responses that can occur in female by-stander rats...
  97. ncbi Automated mouse euthanasia in an individually ventilated caging system: system development and assessment
    Alyssa R McIntyre
    Tri Institutional Training Program in Laboratory Animal Medicine and Science, Memorial Sloan Kettering Cancer Center, Rockefeller University, New York, NY, USA
    J Am Assoc Lab Anim Sci 46:65-73. 2007
    ..This system was safe, effective, and labor-saving for euthanizing large numbers of mice in an aesthetically acceptable and humane manner compatible with recommendations provided in the ACLAM 2005 Report on Euthanasia...
  98. ncbi Report of the 2006 RSPCA/UFAW Rodent Welfare Group meeting
    Barney Reed
    Research Animals Department, Science Group, RSPCA, Wilberforce Way, Southwater, West Sussex RH13 9RS, UK
    Lab Anim (NY) 37:216-22. 2008
    ..Topics included the housing and husbandry of mice and rats, refining the use of rodents in asthma research, good practice for the euthanasia of rodents using carbon dioxide and achieving reduction by sharing genetically modified mice...
  99. ncbi A comprehensive, barcoded system for the management of animal information in a research facility
    C Pryor
    Lab Animal Resources, Merck Research Laboratories, PO Box 4, WP44-201, Sumneytown Pike, West Point, PA 19486, USA
    Lab Anim (NY) 30:36-8. 2001
    ..The authors describe an easy-to-use barcode-based animal tracking system that has improved record keeping and data retrieval and proved instrumental in the containment of an outbreak...
  100. ncbi Should clinical complications affect USDA pain categories? C is correct
    Gail T Colbern
    Laboratory Animal Resources at Genentech, Inc, 1 DNA Way, MS 72, South San Francisco, CA, USA
    Lab Anim (NY) 36:14. 2007
  101. ncbi Affordable noise control in a laboratory animal facility
    David L Carlton
    Laboratory Animal Resources and Research, Texas A and M University, Building 972, Agronomy Road, College Station, TX 77843 4473, USA
    Lab Anim (NY) 31:47-8. 2002

Research Grants62

  1. Study of Genetics, Endotoxin and Allergen (SAGE)
    Karin Pacheco; Fiscal Year: 2007
    Symptoms and sensitization to laboratory animals (LA) are frequent occupational hazards of research scientists, technicians, and others who work with animals. Animal allergen and endotoxin are the two main exposures for these workers...
  2. A Novel Detector for Combined Optical and PET Imaging
    Arion Chatziioannou; Fiscal Year: 2007
    ..Furthermore, this imaging system will be of reduced cost, due to its field of view customized to the application of small animal imaging. ..
  3. IBANGS Annual Meeting support
    John Crabbe; Fiscal Year: 2005
    ..This young society represents an opportunity to attract a core group of young investigators to alcohol research during their formative years. ..
  4. Genetics of Longevity and Age-Sensitive Traits in Mice
    Richard Miller; Fiscal Year: 2008
    ..abstract_text> ..
  5. Identity and Function of CNS Progenitor Cell Genes
    Harley Kornblum; Fiscal Year: 2007
    ..In another set of experiments, microarray analysis will be used to compare gene expression in PTEN-deficient and wild type neurosphere cultures to discover genes and gene networks regulating self-renewal. ..
  6. Methamphetamine, Stress and SIV: Effects at Blood-Brain Barrier and Lymph Nodes
    John P Capitanio; Fiscal Year: 2010
    ..Relevance ..
  7. POSITRON TOMOGRAPHY IN ISCHEMIC HEART DISEASE
    Heinrich Schelbert; Fiscal Year: 2004
    ....
  8. WILD DERIVED MOUSE STOCKS--NEW MODELS FOR AGING RESEARCH
    Richard Miller; Fiscal Year: 2004
    ....
  9. METABOLISM OF CARCINOGENIC TOBACCO SPECIFIC NITROSAMINES
    Stephen Hecht; Fiscal Year: 2003
    ..abstract_text> ..
  10. THE ECONOMICS OF POLYDRUG ABUSE
    RICHARD MEISCH; Fiscal Year: 2001
    ..The overall aim is to determine what combinations of drugs are taken when the cost of each drug is varied. The results will demonstrate a systematic and quantitative strategy for the analysis of polydrug abuse. ..
  11. SUPPORT FOR INSTITUTE FOR LABORATORY ANIMAL RESEARCH
    JOANNE ZURLO; Fiscal Year: 2008
    ..The overall objectives of ILAR are: [unreadable] to promote humane and appropriate care and use of laboratory animals; [unreadable] to provide a forum within the National Academies for the National Institutes of Health to ..
  12. Coronary Vasa Vasorum - Role of 3D Branching Geometry
    Erik Ritman; Fiscal Year: 2009
    ..abstract_text> ..
  13. CARCINOGENIC CYCLIC NITROSAMINE DNA ADDUCTS
    Stephen S Hecht; Fiscal Year: 2010
    ..The proposed research is significant because of the known human exposure to these carcinogens through the diet, tobacco products, and endogenous formation. ..
  14. MULTIDISCIPLINARY MICRO CT-3D IMAGING FACILITY
    Erik Ritman; Fiscal Year: 2001
    ..AIM IV - Continue to provide the 3D micro-CT imaging service to investigator-users so that this experience will guide innovation, improvement and/or expansion of the imaging repertoire of the micro-CT methodology. ..
  15. PATHOLOGY OF THE LABORATORY MOUSE
    John Sundberg; Fiscal Year: 2006
    ..The Workshop will accommodate 16 participants who will have an opportunity to interact with a group of prominent mouse pathologists and geneticists from both TJL, and other leading institutions. ..
  16. Micro-CT of Solute Transport in Organs & Tissue Scaffolds
    Erik Ritman; Fiscal Year: 2009
    ....
  17. Imaging Serotonergic Transmission in HIV Depression
    Martin Pomper; Fiscal Year: 2006
    ..abstract_text> ..
  18. PSMA-based SPECT Tracers for Prostate Cancer Imaging
    Martin Pomper; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  19. PSMA-based PET Ligands for Prostate Cancer Imaging
    Martin Pomper; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  20. Integrative mechanisms of cortical circuits
    GORDON MURRAY SHEPHERD; Fiscal Year: 2010
    ..The results will therefore suggest new principles for the functioning of cortical modules, and for the neural basis of normal odor processing. ..
  21. Amygdalar Modulation of Fear-Conditioned Changes in REM Sleep
    ADRIAN MORRISON; Fiscal Year: 2009
    ..It is very important to investigate the serotonergic modulation of CFC in animals because drugs that influence 5-HT function have widespread acceptance for treating PTSD yet little is known about their actions in related animal models. ..
  22. GCPII-Based Brain Imaging Agents
    Martin Pomper; Fiscal Year: 2008
    ..Working with our knowledge of PSMA/GCPII imaging and the recently published crystal structure of PSMA, we intend to pursue new derivatives suitable for imaging GCPII within the central nervous system ..
  23. PSMA-based Gene Reporter-Probe System(RMI)
    Martin Pomper; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  24. Senselab: Integration of Multidisciplinary Sensory Data
    Gordon Shepherd; Fiscal Year: 2008
    ..abstract_text> ..
  25. Lung Cancer Chemoprevention: Isothiocyanates, inositol
    Stephen Hecht; Fiscal Year: 2008
    ..abstract_text> ..
  26. A Novel Device to Allow Zoom-In Imaging for PET Scanners
    Yuan Chuan Tai; Fiscal Year: 2007
    ..of molecular imaging to study disease models, pharmacokinetics of new drugs, and gene expression using small laboratory animals via in vivo imaging has shown promising results...
  27. PATHOGENESIS OF MURINE PARVOVIRUS FIELD STRAINS
    David Besselsen; Fiscal Year: 2007
    ..In addition, these studies will provide information about perturbations in host physiology and gene expression induced by murine parvoviruses, and basic scientific information about parvovirus host interaction. ..
  28. Role of Cytokines in Two Hit Organ Injury
    Jean Nemzek; Fiscal Year: 2006
    ..Successful completion of these aims could impact current two hit theories and use of immune therapy in septic patients exposed to additional inflammatory insults. ..
  29. GENETICS OF AGE SENSITIVE TRAITS IN MICE
    Richard Miller; Fiscal Year: 2003
    ..At best, the program may permit the localization of loci that influence multiple age-sensitive domains and are thus plausible candidates for genes that regulate the rate of aging per se. ..
  30. Circadian Rhythms: Photic Sensitivity and Behavior
    Roberto Refinetti; Fiscal Year: 2003
    ..abstract_text> ..
  31. 5 NUCLEASE ASSAYS FOR RODENT HEALTH MONITORING
    David Besselsen; Fiscal Year: 2002
    ..FFPNA will greatly enhance the diagnostic capabilities for routine health monitoring of laboratory rodents and will provide a viable, cost-effective alternative for RAP testing. ..
  32. BRAINSTEM MECHANISMS OF ALERTING
    ADRIAN MORRISON; Fiscal Year: 2002
    ..These experiments address basic mechanisms likely to be altered in narcolepsy and PTSD. ..
  33. Mark I Model 68A Rodent/Cell line Gamma Irradiator
    Sanford Feldman; Fiscal Year: 2004
    ....
  34. MURINE MODEL FOR MONKEY B VIRUS INFECTION
    JERRY RITCHEY; Fiscal Year: 2004
    ..abstract_text> ..
  35. A Proteomic Analysis of Neural Progenitors
    Harley Kornblum; Fiscal Year: 2004
    ..It is anticipated that these pilot studies will pave the way for new avenues in the study of neural progenitor cell biology. ..
  36. Lovelace Respiratory Symposium 2003
    Rogene Henderson; Fiscal Year: 2003
    ..Future topics will be developed with the same sensitivity to meeting the information needs of our audience. Continuing medical education credits are available through the University of New Mexico School of Medicine. ..
  37. CNS METABOLIC CORRELATES OF HIV DEMENTIA BY MRS IMAGING
    Martin Pomper; Fiscal Year: 2001
    ..abstract_text> ..
  38. Purchase of Ventilated Caging Systems and Workstations
    Debra Hickman; Fiscal Year: 2006
    ..We currently have 5 rooms that house rodents in ventilated filter-top caging but do not have access to a workstation. ..
  39. Tobacco Carcinogenesis
    Stephen Hecht; Fiscal Year: 2005
    ..Steven Tannenbaum (MIT), Dr. Jack Henningfield (Johns Hopkins and Pinney Associates), Drs. Jeffrey Seeman and Anthony Tricker (Philip Morris), and Dr. John Lauterbach (an independent consultant, formerly with Brown and Williamson). ..
  40. SCREENING MICE FOR AUDITORY & NEUROBEHAVIORAL PHENOTYPES
    JAMES WILLOTT; Fiscal Year: 2002
    ..Johnson. This will be accompanied by development of an easy-to-use software/ hardware package that will integrate all screening techniques in a single, serial protocol for use on individual mice. ..
  41. In Vivo Myocardial Microcirculatory Function
    ERIK LEO RITMAN; Fiscal Year: 2010
    ..abstract_text> ..
  42. SIMIAN AIDS: SOCIAL STRESS, ENDOCRINE & IMMUNE FUNCTION
    John Capitanio; Fiscal Year: 2004
    ..abstract_text> ..
  43. Hearing in Belgian Waterslager Canaries
    AMANDA LAUER; Fiscal Year: 2004
    ..Thus, the proposed experiments will increase our understanding of the functional consequences of hearing impairment in these birds, and of hearing impairment in general. ..
  44. Dinitroaniline Specificity for Tubulin
    Naomi Morrissette; Fiscal Year: 2005
    ....
  45. RESEARCH TRAINING FOR VETERINARIANS: ANIMAL MODELS
    John Sundberg; Fiscal Year: 2008
    ..The investigators ask to maintain the three slots currently funded. This program is designed to meet the increasing demand for scientists in functional genomics research. ..
  46. Mechanisms of Dinitroaniline Action, Selectivity and Resistance
    Naomi S Morrissette; Fiscal Year: 2010
    ..In summary, we believe that further study of the dinitroanilines will elucidate new aspects of tubulin function and define novel ways to specifically disrupt parasite tubulins. ..
  47. SUPPORT FOR INSTITUTE FOR LABORATORY ANIMAL RESEARCH
    JOANNE ZURLO; Fiscal Year: 2001
    ..Sample illustrative occupational health and safety plans should be developed for personnel working in large and small holdings of NHP. ..
  48. DEMOLITION AND ASTHMA IN CHICAGO PUBLIC HOUSING
    Samuel Dorevitch; Fiscal Year: 2006
    ....
  49. Workshop on Science-Based Guidelines for Lab Animals
    JOANNE ZURLO; Fiscal Year: 2003
    ..abstract_text> ..
  50. INSTITUTE FOR LABORATORY ANIMAL RESEARCH
    JOANNE ZURLO; Fiscal Year: 2004
    ..will be achieved by accomplishing the following: by promoting humane and appropriate care and use of laboratory animals; by providing a forum within the National Academy of Sciences for the National Institutes of Health to ..
  51. Enhancing Human Subjects Research Protection, Year Two
    ROBERT LOWMAN; Fiscal Year: 2003
    ..abstract_text> ..
  52. Novel Approaches to Studying the Situ Bioremediation of Complex Mixtures
    ROLF HALDEN; Fiscal Year: 2009
    ..abstract_text> ..
  53. IMPORTANCE OF PERIPHERAL SITES OF ANALGESIC ACTION
    Jerry Collins; Fiscal Year: 2001
    ..Attempts will be made to obtain and test new compounds that do not cross the blood-brain barrier. ..
  54. Chemoprevention in Mice after Tobacco Smoke Exposure
    Hanspeter Witschi; Fiscal Year: 2004
    ..Eventually, these preclinical studies in an animal model of "former smokers" will help to evaluate the potential usefulness and also possible dosage regimens of chemopreventive agents characterized by their suppressing action. ..
  55. ANALYSES OF COMMUNICATION SOUNDS IN AUDITORY MIDBRAIN
    CHRISTINE PORTFORS; Fiscal Year: 2005
    ..This study will establish the extent of selectivity among social vocalizations in the IC and the contribution of combination sensitivity to selectivity. ..
  56. Development of a rapid behavioral tinnitus screen for rats.
    Jeremy Turner; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  57. Modulation of age-related changes in the auditory system
    JAMES WILLOTT; Fiscal Year: 2008
    ..The ultimate goal is to develop new approaches for amelioration and treatment ofpresbycusis and other hearing disorders. [unreadable] [unreadable]..
  58. Developing techniques for studying tinnitus in animals
    Henry Heffner; Fiscal Year: 2007
    ..Knowing the pitch of an animal's tinnitus is necessary to distinguish between physiological changes due to hearing loss from those due to tinnitus. [unreadable] [unreadable]..
  59. Auditory Plasticity in the Aged Mouse
    Jeremy Turner; Fiscal Year: 2005
    ..abstract_text> ..
  60. Alopecia and Ulcerative Dermatitis in B6 Mice
    John Sundberg; Fiscal Year: 2007
    ..Future work will apply findings to human patients to either modify lifestyle or more appropriately treat CCCA to reduce suffering and disfiguration. [unreadable] [unreadable] [unreadable]..