Genomes and Genes
Summary: The analysis of an activity, procedure, method, technique, or business to determine what must be accomplished and how the necessary operations may best be accomplished.
Publications260 found, 100 shown here
- Creating a systems approach to patient safety through better teamworkStephen M Powell
Healthcare Team Training, LLC, USA
Biomed Instrum Technol 40:205-7. 2006....
- The intersection of patient safety and nursing researchPatricia Hinton Walker
Graduate School of Nursing, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
Annu Rev Nurs Res 24:3-15. 2006....
- Systems analysis of plant cell wall degradation by the model filamentous fungus Neurospora crassaChaoguang Tian
Department of Plant and Microbial Biology, California Institute for Quantitative Biosciences QB3 Chemistry Mass Spectrometry Facility, University of California, Berkeley, CA 94720, USA
Proc Natl Acad Sci U S A 106:22157-62. 2009..These results show that the powerful tools available in N. crassa allow for a comprehensive system level understanding of plant cell wall degradation mechanisms used by a ubiquitous filamentous fungus...
- Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis proteinMarkus Rehm
Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland
EMBO J 25:4338-49. 2006..Our study supports the hypothesis that high levels of XIAP control caspase activation and substrate cleavage, and may promote apoptosis resistance and sublethal caspase activation in vivo...
- A systems analysis of mutational effects in HIV-1 protease and reverse transcriptaseTrevor Hinkley
ETH Zurich, Institute of Integrative Biology, Zurich, Switzerland
Nat Genet 43:487-9. 2011..We find that the fitness landscape of HIV-1 protease and reverse transcriptase is characterized by strong epistasis...
- Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapyAndreas U Lindner
Centre for Systems Medicine, Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland
Cancer Res 73:519-28. 2013..Together, our findings offer a ready clinical tool with the potential to tailor chemotherapy to individual patients...
- Designing a quality improvement intervention: a systematic approachM A van Bokhoven
Centre for Quality of Care Research Department of General Practice, Maastricht University, The Netherlands
Qual Saf Health Care 12:215-20. 2003..Decisions that have to be made during the design process of a quality improvement intervention are visualised, allowing them to serve as a starting point for a systematic evaluation of the intervention...
- A dynamical systems analysis of afferent control in a neuromechanical model of locomotion: I. Rhythm generationLucy E Spardy
Department of Mathematics, University of Pittsburgh, Pittsburgh, PA 15260, USA
J Neural Eng 8:065003. 2011....
- Availability and use of emergency obstetric care services in public hospitals in Laos PDR: a systems analysisXaysomphou Douangphachanh
Reproductive Health and Research, World Health Organization, Switzerland
Biosci Trends 4:318-24. 2010..These data can therefore help government to assign and allocate budgets appropriately, and help policymakers and planners to identify systemic bottlenecks and prioritize solutions and will help in improving maternal health...
- Bone physiology, disease and treatment: towards disease system analysis in osteoporosisTeun M Post
Pharmacokinetics, Pharmacodynamics, Pharmacometrics P3, Schering Plough, Oss, The Netherlands
Clin Pharmacokinet 49:89-118. 2010....
- Persistence of unsafe practice in everyday work: an exploration of organizational and psychological factors constraining safety in the operating roomS Espin
Faculty of Community Services, Ryerson University, 350 Victoria Street, Toronto, Canada
Qual Saf Health Care 15:165-70. 2006....
- Communication failures in the operating room: an observational classification of recurrent types and effectsL Lingard
University of Toronto, Toronto, Ontario, Canada
Qual Saf Health Care 13:330-4. 2004..This study was part of a larger project to develop a team checklist to improve communication in the OR...
- Introducing soft systems methodology plus (SSM+): why we need it and what it can contributeJeffrey Braithwaite
Graduate Management Programs, Faculty of Medicine, University of New South Wales
Aust Health Rev 25:191-8. 2002....
- Glucose sensing in the pancreatic beta cell: a computational systems analysisLeonid E Fridlyand
Department of Medicine, The University of Chicago, Chicago, IL 60637, USA
Theor Biol Med Model 7:15. 2010..The goal of this work is to uncover contributions of the cytoplasmic and mitochondrial processes in this secretory coupling mechanism using mathematical modeling in a systems biology approach...
- Regulation of release factor expression using a translational negative feedback loop: a systems analysisRussell Betney
School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom
RNA 18:2320-34. 2012..e., control precision) is proportional to eRF1 affinity for the premature stop codon. The validated model represents an important tool to analyze this and other translational negative feedback loops...
- Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilizationJasmin Schmid
Centre for Systems Medicine, Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St Stephen s Green, Dublin 2, Ireland
J Biol Chem 287:41546-59. 2012....
- Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade CCarmen Elena Gómez
Department of Molecular and Cellular Biology, Centro Nacional de Biotecnologia, CSIC, Madrid, Spain
PLoS ONE 7:e35485. 2012..Here we describe using systems analysis the biological and immunological characteristics of the attenuated vaccinia virus Ankara strain expressing ..
- Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesionXiaodong Huang
Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093, USA
BMC Syst Biol 2:49. 2008....
- Linear and nonlinear systems analysis of the visual system: why does it seem so linear? A review dedicated to the memory of Henk SpekreijseRobert Shapley
Center for Neural Science, New York University, 4 Washington Place, New York, NY 10003, USA
Vision Res 49:907-21. 2009Linear and nonlinear systems analysis are tools that can be used to study communication systems like the visual system. The first step of systems analysis often is to test whether or not the system is linear...
- Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responsesDaniel E Zak
Seattle Biomedical Research Institute, Seattle, WA 98109, USA
Proc Natl Acad Sci U S A 108:11536-41. 2011..Taken together, these results demonstrate that SHARPIN is an essential adaptor downstream of the branch point defined by the panr2 mutation in NEMO...
- Intracranial fluid dynamics in normal and hydrocephalic states: systems analysis with phase-contrast magnetic resonance imagingGiovanni De Marco
Department of Biophysics and Image Processing, Northern Hospital, and University of Picardie Jules Verne, Amiens, France
J Comput Assist Tomogr 28:247-54. 2004..To present a novel magnetic resonance (MR) method of analysis of cerebrospinal fluid (CSF) flow dynamics...
- Metabolic systems analysis to advance algal biotechnologyBrian J Schmidt
Department of Biomedical Engineering, University of Virginia, Health System, Charlottesville, VA 22908, USA
Biotechnol J 5:660-70. 2010....
- Systems analysis in health care: framework and exampleE Ammenwerth
Department of Medical Informatics, University Medical Center Heidelberg, Germany
Methods Inf Med 41:134-40. 2002..Therefore, we aimed to support systematic systems analysis in health care by developing a comprehensive framework that presents and describes potential areas of analysis...
- Measurement of technical efficiency of public hospitals in Kenya: using Data Envelopment AnalysisJoses M Kirigia
World Health Organisation, Regional Office for Africa, Medical School, Harare, Zimbabwe
J Med Syst 26:39-45. 2002..The study singled out the inefficient hospitals and provided the magnitudes of specific input reductions or output increases needed to attain technical efficiency...
- Intracranial pressure waves: characterization of a pulsation absorber with notch filter properties using systems analysis: laboratory investigationRui Zou
Neurosurgery Department, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
J Neurosurg Pediatr 2:83-94. 2008..ICP) and arterial blood pressure can be quantitatively characterized using a newly developed technique in systems analysis, the time-varying transfer function...
- Systems analysis of cellular networks under uncertaintyHans Michael Kaltenbach
Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland
FEBS Lett 583:3923-30. 2009..A deeper understanding, better scaling, and the ability to combine the approaches pose formidable challenges for future theory developments...
- Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania majorArvind K Chavali
Department of Biomedical Engineering, University of Virginia, Charlottesville, VA 22908, USA
Mol Syst Biol 4:177. 2008..major is the first of its kind for a protozoan. It can serve as a tool for clarifying discrepancies between data sources, generating hypotheses that can be experimentally validated and identifying ideal therapeutic targets...
- Understanding and responding to adverse eventsCharles Vincent
Department of Surgical Oncology and Technology, Imperial College School of Science, Technology, and Medicine, St Mary s Hospital, London
N Engl J Med 348:1051-6. 2003
- Biochemical systems analysis of genome-wide expression dataE O Voit
Department of Biometry and Epidemiology, 135 Rutledge Avenue, Medical University of South Carolina, Charleston, SC 29425, USA
Bioinformatics 16:1023-37. 2000..Modern methods of genomics have produced an unprecedented amount of raw data. The interpretation and explanation of these data constitute a major, well-recognized challenge...
- Systems analysis unfolds the relationship between the phosphoketolase pathway and growth in Aspergillus nidulansGianni Panagiotou
Center for Microbial Biotechnology, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark
PLoS ONE 3:e3847. 2008..niger and A. oryzae. Here we identified the gene coding for a novel metabolic pathway in A. nidulans, namely the phosphoketolase pathway, and investigated the role of an increased phosphoketolase activity...
- An illustration of whole systems thinkingKanwal Kalim
Centre for Health Informatics, City University, London, UK
Health Serv Manage Res 19:174-85. 2006..Soft systems thinking is the best approach, given the complexity of health care. It is a flexible, cost-effective solution, which should be a prerequisite before any new health policy is launched...
- Computer systems analysis of spaceflight induced changes in left ventricular massRichard L Summers
Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA
Comput Biol Med 37:358-63. 2007..This data was further evaluated in a systems analysis approach using a well-established advanced computer model of circulatory functioning...
- Systems analysis of small signaling modules relevant to eight human diseasesKelly F Benedict
Department of Biomedical Engineering, University of Virginia Health System, One Boar s Head Pointe, Charlottesville, VA 22908, USA
Ann Biomed Eng 39:621-35. 2011..addiction, Alzheimer's disease, cancer, diabetes, HIV, heart disease, malaria, and tuberculosis, we show that systems analysis of small (4-25 species), bounded protein signaling modules rapidly generates new quantitative knowledge from ..
- Systems analysis of collaboration in 5 national tobacco control networksDouglas A Luke
Center for Tobacco Policy Research, Brown School of Social Work, Washington University in St Louis, St Louis, MO 63112, USA
Am J Public Health 100:1290-7. 2010....
- Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysisMarc T Facciotti
Institute for Systems Biology, 1441 North 34th Street, Seattle, WA 98103, USA
BMC Syst Biol 4:64. 2010..Therefore, a relatively quick and inexpensive strategy for observing changes in large fractions of the genetic elements is highly desirable...
- Optimizing bioconversion pathways through systems analysis and metabolic engineeringDaniel E Stafford
Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Proc Natl Acad Sci U S A 99:1801-6. 2002..We demonstrate this method in the indene bioconversion network of Rhodococcus modified for the overproduction of 1,2-indandiol, a key precursor for the AIDS drug Crixivan...
- Systems analysis of GLP-1 receptor signaling in pancreatic β-cellsYukari Takeda
Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, Japan
Am J Physiol Cell Physiol 301:C792-803. 2011..To examine robustness of the signaling system in controlling [cAMP], magnitudes of AC and PDE activities were compared in the presence or absence of GLP-1 and/or the PDE inhibitor IBMX.(1)...
- The critical path method to analyze and modify OR-workflow: integration of an image documentation systemA Endress
Department of Obstetrics and Gynecology, University of Tuebingen, Tuebingen, Germany
Minim Invasive Ther Allied Technol 15:177-86. 2006..It is an appropriate method to transparently show integration possibilities and to define workflow-based requirements for the development process of new systems...
- Complex nursing systemsThomas R Clancy
Professional Services, Mercy Hospital, Iowa City, IA 52245, USA
J Nurs Manag 13:192-201. 2005..This paper further discusses the merits of computational modelling and simulation which can assist nurse administrators predict the results of their decisions through a virtual complex system environment...
- Integrating patient safety into practiceChristine Baldrey
Clinical Nurse Consultant, Continence Service, The Royal Melbourne Hospital, Victoria, Australia
J Nurs Care Qual 21:14. 2006
- Great Safety Performance: an improvement process using leading indicatorsDianne Dyck
Occupational Health and Safety, ENMAX Corporation, Calgary, Alberta
AAOHN J 52:511-20. 2004..By using the Great Safety Performance model, organizations can design and implement a variety of high leverage improvement initiatives specific to their business situations...
- Clinical risk management and patient safety education for nurses: a critiqueMegan Jane Johnstone
Division of Nursing and Midwifery, School of Health Sciences, RMIT University, Bundoora, Melbourne, VIC 3083, Australia
Nurse Educ Today 27:185-91. 2007....
- System weaknesses as contributing causes of accidents in health careSven Ternov
Ergonomics and Aerosol Technology, Department of Design Sciences, Lund Institute of Technology, Lund, Sweden
Int J Qual Health Care 17:5-13. 2005..Accidents in health care, resulting in injury or death to the patient, are a matter of considerable concern. The aim of this study is to examine whether system weaknesses can contribute to these accidents, and if so, how...
- Transforming care at the bedside: designing new care systems in an age of complexityMary Viney
Seton Healthcare Network, and School of Nursing, The University of Texas at Austin, 1700 Red River, Austin, TX 78701, USA
J Nurs Care Qual 21:143-50. 2006..The article discusses the innovation process and the change cycles, impact of various innovations, and lessons learned...
- Incident reporting in one UK accident and emergency departmentCatherine M Tighe
Clinical Safety Research Unit, Department of Biosurgery and Surgical Technology, Imperial College, St Mary s Campus, Praed Street, London W2 1NY, United Kingdom
Accid Emerg Nurs 14:27-37. 2006..This research may have implications for the incident reporting process in other specialities as well as in other hospitals...
- Safety in the academic medical center: transforming challenges into ingredients for improvementDavid Blumenthal
Institute for Health Policy, Massachusetts General Hospital and Partners Health System, 55 Fruit Street, Boston, MA 02114, USA
Acad Med 81:817-22. 2006....
- FMEA and RCA: the mantras of modern risk managementJ W Senders
Toronto, Ontario M6R 2X5, Canada
Qual Saf Health Care 13:249-50. 2004
- Analysis of clinical incidents: a window on the system not a search for root causesC A Vincent
Qual Saf Health Care 13:242-3. 2004..3 New risk management and patient safety programmes-whether local or national-rely on incident reporting to provide data on the nature of safety problems and to provide indications of the causes of those problems and the likely solutions...
- Quality and safety by designJ B Battles
Agency for Healthcare Research and Quality AHRQ, Center for Quality Improvement and Patient Safety, 540 Gather Road, Rockville, MD 20850, USA
Qual Saf Health Care 15:i1-3. 2006..In order to bring about major improvements in quality and safety, these design methods can and should be used to redesign healthcare delivery systems...
- Interview with Frances A. Griffin, Institute for Healthcare Improvement. Interview by Diane E. FeatherstonFrances A Griffin
J Nurs Care Qual 20:369-72. 2005
- A human factors engineering paradigm for patient safety: designing to support the performance of the healthcare professionalB T Karsh
Industrial and Systems Engineering, University of Wisconsin Madison, Madison, WI, USA
Qual Saf Health Care 15:i59-65. 2006..The concepts of human performance and hazard reduction are explained...
- Industrial strength. Patient safety means leading pre-industrial health care into a post-industrial worldChuck Appleby
Trustee 55:10-4, 19, 2. 2002..Innovative methods of improving patient safety--including one pioneered by Toyota--highlight the need for hospitals and their staff to adopt a post-industrial mindset...
- Expertise isn't the only answer to leadership in safetyKarlene Kerfoot
Nursing and Patient Care Services, Clarian Health, Indianapolis, IN, USA
Nurs Econ 23:100-2. 2005..In the words of Collins (2001), "Good is the enemy of Great" (p. 1). With new eyes that represent diverse cognitive skills, we will overcome our blindness to defects and move from good to great...
- Patient safety: planting the seedStephanie S Poe
Johns Hopkins Hospital, The Johns Hopkins University School of Nursing, Baltimore, MD 21287, USA
J Nurs Care Qual 20:198-202. 2005
- Error recovery in a hospital pharmacyL Kanse
University of Queensland, Brisbane, Australia
Ergonomics 49:503-16. 2006..Guidance is given on how performance in recovery could be measured. A case is made for supporting recovery as an addition to prevention-based safety methods...
- How can we improve the nursing work environment?Julie Holden
Maternal Newborn Services, Melrose Wakefield Hospital, Melrose, MA, USA
MCN Am J Matern Child Nurs 31:34-8. 2006..This transformation could mean that the terms "Nursing Organizations" and "Learning Organizations" would not have to be oxymorons...
- Narrativizing errors of care: critical incident reporting in clinical practiceRick Iedema
Centre for Clinical Governance Research, School of Public Health and Community Medicine, The University of New South Wales, Sydney 2052 NSW, Australia
Soc Sci Med 62:134-44. 2006....
- "Going solid": a model of system dynamics and consequences for patient safetyR Cook
Department of Anesthesia and Critical Care, University of Chicago, Chicago, IL 60615, USA
Qual Saf Health Care 14:130-4. 2005..Because the model addresses the dynamic aspects of safety, it is particularly suited to understanding current conditions in modern healthcare delivery and the way these conditions may lead to accidents...
- Will the future continue to repeat the past?S J Woodward
Qual Saf Health Care 14:74. 2005
- Case management and patient safety: opportunities for process and performance improvementSherrie Dulworth
Milliman Care Guidelines, Seattle, Wash, USA
Case Manager 16:69-72; quiz 73. 2005..Some case managers voice doubts about the ability to affect safety because they typically are not direct caregivers. Is it realistic to expect case managers and their organizations to influence and improve patient safety?..
- [List of complications--reduction of errors and complications by elimination of unsafe actions and conditions]M Staubli
Medizinische Abteilung, Spital Zollikerberg, Zollikerberg
Ther Umsch 62:199-204. 2005..The principle for the reduction of such events is the elimination of unsafe actions and conditions and apparently harmless errors in daily diagnostic and therapeutic interventions in order to avoid the potentially serious consequences...
- Patient safety and the art and science of medicineWilliam F Minogue
Maryland Patient Safety Center, USA
Md Med 6:13-5. 2005
- [Failure prevention in clinical practice through identification of failure examples]M L Hansis
RHON KLINIKUM AG, Bad Neustadt
Ther Umsch 62:179-83. 2005..Recognizing patterns of underlying causes for errors is the key to effective error prevention. In many cases the true cause might be predominantly organizational...
- [Preliminary results of an anonymous internet-based reporting system for critical incidents in ambulatory primary care]A Brun
Facharzt FMH fürAllgemeinmedizin, Hauptstrasse 14, CH 3512, Walkringen
Ther Umsch 62:175-8. 2005..As incentives for more intensive participation there are the hope for comments on reported cases by other participants and the expectation that reported errors will be avoided by the readers...
- [Critical incidents]D Scheidegger
Departement Anästhesie, Universitäitsspital Basel
Ther Umsch 62:169-74. 2005....
- [Experiences with "incident reporting" at the East Switzerland Childrens Hospital]B Kehrer
Facharztfür Kinderchirurgie, Tutilostrasse 5, CH 9011 St Gallen
Ther Umsch 62:161-7. 2005..In Switzerland a National Foundation for Patient Safety has been created for supporting all the acting professionals in the healthcare system in their challenging task...
- Implementation of patient centeredness to enhance patient safetyKarin Janine Berntsen
Jamul, CA 91935, USA
J Nurs Care Qual 21:15-9. 2006
- Creating an organizational culture for medication safetyRobin Donohoe Dennison
University of Kentucky College of Nursing, Lexington, KY, USA
Nurs Clin North Am 40:1-23. 2005..collaboration; Staffing: adequate number and staffing mix; Administration support for the clinical goal of patient safety; Failure mode and effects analysis with team member involvement; Environment and equipment to support patient safety..
- Violations and migrations in health care: a framework for understanding and managementR Amalberti
IMASSA, Cognitive Science Department, Bretigny sur Orge, France
Qual Saf Health Care 15:i66-71. 2006..Violations cannot be eliminated but they can be managed. Solutions are specific to each step of the model, with a mix of relaxing constraints, increasing peer control (staff), and constraining dangerous individuals...
- Accidents waiting to happen: the contribution of latent conditions to patient safetyC M Lowe
NHS National Patient Safety Agency, 4 8 Maple Street, London W1T 5HD, UK
Qual Saf Health Care 15:i72-5. 2006..A better understanding of these elements and specific healthcare design challenges will result in improved patient safety...
- First do no harm: integrating patient safety and quality improvementZubina Mawji
Lehigh Valley Hospital and Health Network, 1210 S Cedar Crest Blvd, Suite 3600, Allentown, PA 18103, USA
Jt Comm J Qual Improv 28:373-86. 2002..The projects stress delivery of cost-effective medical care while reducing preventable adverse events through improved communication, process redesign, and evidence-based protocol use...
- Breaking the error chainDavid Crouch
Nurs Times 99:22-5. 2003
- St. John Health System and patient safetyFrancis Wilson
Medical Services, St John Health System, Warren, Michigan, USA
Qual Manag Health Care 12:46-52. 2003..John Health System developed a comprehensive approach to improving patient safety and how that was implemented in our 8 hospital system with independent medical staffs...
- Nursing is essential to improving patient safetyPamela Mitchell
J Adv Nurs 38:109-10. 2002
- Human factors and systems engineering approach to patient safety for radiotherapyA Joy Rivera
Industrial and Systems Engineering, University of Wisconsin Madison, Madison, WI 53706, USA
Int J Radiat Oncol Biol Phys 71:S174-7. 2008..However, an understanding of the human factors and systems engineering is lacking, and confusion remains about what it means to apply their principles. This paper provides a primer on them and their applications to patient safety...
- Patient Safety Leadership WalkRoundsAllan Frankel
Partners HealthCare System, Boston, USA
Jt Comm J Qual Saf 29:16-26. 2003..Executives are surveyed quarterly about actions they have taken as a direct result of WalkRounds and are asked what they have learned from the rounds...
- John M. Eisenberg Patient Safety Awards. System innovation: Veterans Health Administration National Center for Patient SafetyJeffrey R Heget
Veterans Affairs VA National Center for Patient Safety, 24 Frank Lloyd Wright Drive, Lobby M, P O Box 486, Ann Arbor, MI 48106 0486, USA
Jt Comm J Qual Improv 28:660-5. 2002..NCPS's aim is to foster a culture of safety in the Department of Veterans Affairs (VA) by developing and providing patient safety programs and delivering standardized tools, methods, and initiatives to the 163 VA facilities...
- Educating physicians prepared to improve care and safety is no accident: it requires a systematic approachD C Aron
Education Office 14 W, Louis Stokes Cleveland DVA Medical Center, 10701 East Blvd, Cleveland, OH 44106, USA
Qual Saf Health Care 11:168-73. 2002..We apply a systems analysis from the field of human error to identify ways in which medical school education can increase the number of ..
- The Veterans Affairs root cause analysis system in actionJames P Bagian
VA National Center for Patient Safety, 2215 Fuller Drive, Ann Arbor, MI 48105, USA
Jt Comm J Qual Improv 28:531-45. 2002..The cases illustrate that broadly applicable, high-impact actions can result from a thorough RCA process...
- From blaming to proactively changing the future: the leader's safety challengeKarlene M Kerfoot
Aurora Health System, Milwaukee, WI, USA
Nurs Econ 26:280-1. 2008..Many nurses have left their positions because they have chosen not to work in a culture of blame. Eliminating all forms of blame is essential for excellence in patient care outcomes and loyalty of staff...
- Root cause analysis in perinatal care: health care professionals creating safer health care systemsM M Boyer
The Women's Center at University Community Hospital, Tampa, Florida, USA
J Perinat Neonatal Nurs 15:40-54. 2001..Risk reduction strategies are presented to make this process meaningful and efficient while promoting the ultimate goal of safer health care systems...
- The safety checklist program: creating a culture of safety in intensive care unitsMarcia M Piotrowski
VA Ann Arbor Healthcare System VAAAHS, Ann Arbor, Michigan, USA
Jt Comm J Qual Improv 28:306-15. 2002....
- Using health care Failure Mode and Effect Analysis: the VA National Center for Patient Safety's prospective risk analysis systemJoseph DeRosier
Department of Veterans Affairs, VA National Center for Patient Safety 10X, 24 Frank Lloyd Wright Drive, Lobby M, PO Box 486, Ann Arbor, MI 48106 0486, USA
Jt Comm J Qual Improv 28:248-67, 209. 2002..The authors describe HFMEA, a five-step process used to proactively evaluate a health care process, and provide examples of a team's forms and actions regarding prostate-specific antigen testing...
- A user's manual for the IOM's 'Quality Chasm' reportDonald M Berwick
Institute for Healthcare Improvement, Boston, USA
Health Aff (Millwood) 21:80-90. 2002....
- Improving medication safety and patient care in the emergency departmentChristopher E Schmidt
Nurse Corps, United States Navy, and Emergency Department, Naval Hospital Jacksonville, Jacksonville, Fla, USA
J Emerg Nurs 29:12-6. 2003..Through participation in a nationwide institute for healthcare improvement initiative, our emergency department performance improvement group focused on human and system factors that contributed to potential medication errors...
- National Patient Safety Agency: improving patient safety across all critical care areasSimon Keady
Women and Children s Services, University College London Hospitals NHS Foundation Trust, UK
Intensive Crit Care Nurs 24:137-40. 2008..This article gives an insight into the rationale and steps currently being undertaken to respond to these recommendations...
- How to make the most of failure mode and effect analysisErik Stalhandske
Department of Veterans Affairs National Center for Patient Safety, 24 Frank Lloyd Wright Drive, Lobby M, PO Box 486, Ann Arbor, MI 48106, USA
Biomed Instrum Technol 37:96-102. 2003..For additional information on HFMEA, visit the VA website at www.patientsafety.gov/HFMEA.html...
- Pursuing safe medication use and the promise of technologyZane Robinson Wolf
La Salle University, School of Nursing and Health Sciences, Philadelphia, PA, USA
Medsurg Nurs 16:92-100. 2007..They use technologic innovations aimed at error prevention, yet medication errors persist. The importance of improved decision making through computerized systems in the prevention of medication errors is emphasized...
- Incident reports--correcting processes and reducing errorsDebra Dunn
St Joseph s Wayne Hospital, NJ, USA
AORN J 78:212, 214-6, 219-20, passim; quiz 235-8. 2003..The steps that guide managers in adapting an incident reporting system that incorporates continuous quality improvement are identified...
- Stopping the error cascade: a report on ameliorators from the ASIPS collaborativeBennett Parnes
Department of Family Medicine, University of Colorado at Denver and Health Sciences Center, Aurora, CO 80045 0508, USA
Qual Saf Health Care 16:12-6. 2007..To present a novel examination of how error cascades are stopped (ameliorated) before they affect patients...
- Cutting healthcare costs without preventable clinical incidents--together we can improveW Nicklin
Ottawa Hospital and School of Nursing, Queen's University, Ottawa
Healthc Pap 2:66-70, discussion 86-9. 2001..Finally, the litigious sensitivity of the public and healthcare systems overall intensifies the "error" element. This element is counter-productive to the openness required for the systems approach...
- Making patients safer! Reducing error in Canadian healthcareG R Baker
Department of Health Administration, University of Toronto
Healthc Pap 2:10-31. 2001..These are not easy tasks and will require investments in new equipment and new skills. These steps are essential if we are to maintain public confidence in healthcare...
- Malpractice prevention, patient safety, and quality of care: a critical linkageL Gregory Pawlson
National Committee for Quality Assurance, 2000 I Street, NW, Suite 500, Washington, DC 20036, USA
Am J Manag Care 10:281-4. 2004....
- Creating a culture of safetyShelia Allen
International Federation of Perioperative Nurses
J Perioper Pract 17:244-6. 2007
- Safeguarding patients: complexity science, high reliability organizations, and implications for team training in healthcareLeslie M McKeon
College of Nursing, Univeristy of Tennessee Health Science Center, Memphis, TN 38163, USA
Clin Nurse Spec 20:298-304; quiz 305-6. 2006..Cultural and system barriers to achieving high reliability performance within healthcare and implications for team training are discussed...
- Transforming care at the bedside: implementation and spread model for single-hospital and multihospital systemsSusan Christie Martin
Center for Quality Improvement and Innovation, University of Pittsburgh Medical Center, 4601 Baum Boulevard, Pittsburgh, PA 15213, USA
J Nurs Adm 37:444-51. 2007..The authors describe Transforming Care at the Bedside as implemented by one of Institute for Healthcare Improvement/Robert Wood Johnson's initial pilot hospitals, including promising outcomes and a model for spreading the initiative...
- Challenges in delivering safe patient care: a commentary on a quality improvement initiativeLynne Currie
Quality Improvement Programme, RCN Institute, Radcliffe Infirmary, Oxford, UK
J Nurs Manag 15:162-8. 2007..In conclusion, the paper describes the implications arising from the quality improvement initiative and the need for further research exploring the nature of safety culture in health-care organizations...
- Replacements of single basic amino acids in the pleckstrin homology domain of phospholipase C-delta1 alter the ligand binding, phospholipase activity, and interaction with the plasma membraneH Yagisawa
Department of Life Science, Faculty of Science, Himeji Institute of Technology, Harima Science Garden City, Hyogo 678 12, Japan
J Biol Chem 273:417-24. 1998..All residues (with the exception of the K43E substitution) found to be critical for the analyzed PLC-delta1 functions are present at the surface of the PH domain shown to contain the Ins(1,4,5)P3 binding pocket...
- The future of human spaceflightM Reichert
German Aerospace Center DLR, 53183 Bonn, Germany
Acta Astronaut 49:495-522. 2001..roadmaps are investigated for space tourism and human missions to the Moon and Mars, based on a comprehensive systems analysis approach...
- Metabolite stress and tolerance in the production of biofuels and chemicals: gene-expression-based systems analysis of butanol, butyrate, and acetate stresses in the anaerobe Clostridium acetobutylicumKeith V Alsaker
Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA
Biotechnol Bioeng 105:1131-47. 2010....
- Access to community pharmacies by the elderly in Illinois: a geographic information systems analysisSwu Jane Lin
Department of Pharmacy Administration, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA
J Med Syst 28:301-9. 2004..The geographic access to community pharmacies appears to be appropriate in Illinois. However, a small portion of rural elderly who do not have a pharmacy in their nearby areas may warrant special attention...
- CSHL 2010 Conference on Molecular Genetics and Bacteria & PhagesDavid J Stewart; Fiscal Year: 2010..areas such as genomics and metagenomics, sociomicrobiology, molecular ecology, structural biology and systems analysis. For many graduate students and postdoctoral fellows, this is the first large meeting at which they have an ..
- 2012 CSHL Bacteria &Phages ConferenceDavid J Stewart; Fiscal Year: 2012..areas such as genomics and metagenomics, sociomicrobiology, molecular ecology, structural biology and systems analysis. For many graduate students and postdoctoral fellows, this is the first large, international meeting at which ..
- Systems Analysis of Cardiac Chromatin StructureThomas M Vondriska; Fiscal Year: 2013..The significance to the clinical realm is to provide a mechanistic basis for how the genome is reprogrammed with disease, such that future therapies can target specific chromatin remodeling events. ..
- Biomedical Computing Support of Cancer Control and SurveillanceDAVID RONEY; Fiscal Year: 2009..This Contract provides computer systems analysis, programming, data management, data analysis, statistical reporting, and documentation services for research ..
- Systems analysis of TGFbeta signaling and SnoN function in liverKunxin Luo; Fiscal Year: 2013..The long-term goal of this project is to understand how proper levels of TGF2 signaling activity are maintained and regulated in normal tissues and primary cells using a system biology approach. ..
- Physical and Functional Systems Analysis of Mammalian MitochondriaJODI M NUNNARI; Fiscal Year: 2013..Collectively, these objectives are designed to provide new insights into the complex etiologies of diseases and have the potential to identify novel therapeutic avenues. ..
- Prognostic &Therapeutic Implications of Breathing Patterns in Acute Lung InjuryFRANK JOSEPH JACONO; Fiscal Year: 2013..as changes in variability of respiratory patterns with ALI and VALI are not appreciated, and a complex systems analysis approach has not previously been applied to these important clinical conditions...
- Impact of Presenilin 2 Mutation and Deficiency on Microglial FunctionSuman Jayadev; Fiscal Year: 2010..b>Systems analysis of multiple genomic datasets reveals PS2 is overrepresented in immune pathways and is co-regulated with ..
- Application of Omics in Lung DiseaseClaire M Doerschuk; Fiscal Year: 2013..Our Program consists of four omics, leading expertise in bioinformatics, integrative systems analysis of complex biological systems, and clinical research, as well as opportunities to use cohorts in large ..
- RECEPTOR INTERACTION WITH GTP-REGULATORY PROTEINSGary L Johnson; Fiscal Year: 2012..Cumulatively, this work represents a mechanistic systems analysis of the function and regulation of an important MAP3K, MEKK1, which is critical in the control of homeostasis...
- Environment Change and Diarrheal Disease: A Natural ExperimentJoseph N S Eisenberg; Fiscal Year: 2012..coli strains over time and across our study region (Specific Aim 2);and 3) Systems analysis to model the role that social capital and migration play in the transmission of enteric pathogens, and to ..
- Receptor Tyrosine Kinase Signaling NetworksJoannes B Hoek; Fiscal Year: 2010..considerable potential of a novel cross-disciplinary approach that combines experimental studies, nonlinear systems analysis and interactive computational models to achieve a quantitative understanding of RTK signaling networks...
- AUDITORY MEMORIES AND VOCAL LEARNINGFrederic E Theunissen; Fiscal Year: 2013..experiments, we will analyze the neurons'tuning and selectivity using state-of-the-art techniques from systems analysis and information theory...
- Forebrain circuits and control of feeding behavior by learned cuesGorica D Petrovich; Fiscal Year: 2013..The proposed goals will be accomplished with a combination of behavioral and neural systems analysis that include selective neurotoxic lesions, anatomical pathway tracing, and imaging with immediate early genes ..
- Proteomic analysis of eukaryotic protein synthesisAndrew J Link; Fiscal Year: 2010..Hence a comprehensive understanding of protein synthesis is needed for systems analysis of both the normal and disease-altered translation process...
- Systems Analysis Vaccine Responses in Healthy and Hyporesponsive HumansAnna Karolina Palucka; Fiscal Year: 2013..abstract_text> ..
- DEVELOPMENT OF A PRIMATE GENOMIC RESOURCEMichael G Katze; Fiscal Year: 2012..To build these resources, we have teamed with the Biological Systems Analysis and Mass Spectrometry group headed by Dr. Richard D. Smith at Pacific Northwest National Laboratory...
- Hsp90 Dependent Rab TetheringWILLIAM EDWARD BALCH; Fiscal Year: 2012..vesicular traffic in the exocytic and endocytic pathways, a result now strongly supported by a comprehensive systems analysis of Hsp90 function in yeast...
- microRNAs and integrative control of cardiopoiesisMark Mercola; Fiscal Year: 2013..is innovative in that it merges state of the art functional screening of miRs with miR target identification and systems analysis in order to expose the logic underying the emergence of distinct cell types in the heart from stem cells.
- Systems analysis of transcriptional interactions underlying foam cell formationStephen A Ramsey; Fiscal Year: 2013..Ramsey to achieve his career goal of becoming an independent investigator in cardiovascular disease-related research, equipped to use experimental and quantitative methods in a synergistic manner. ..
- Dissecting the neural control of social attachmentNIRAO MAHESH SHAH; Fiscal Year: 2011..genetic tools with behavioral analysis, high resolution anatomic and functional neural circuit mapping, and systems analysis of signaling to understand how the brain normally generates social attachments...
- Dissecting the neural control of social attachmentNIRAO MAHESH SHAH; Fiscal Year: 2013..genetic tools with behavioral analysis, high resolution anatomic and functional neural circuit mapping, and systems analysis of signaling to understand how the brain normally generates social attachments...
- An in vitro-in vivo correlation model to predict serum non-transferrin bound ironAmy Barton Pai; Fiscal Year: 2013..Specific Aim 4. Establish the relationship between in vitro labile iron data and in vivo NTBI data - A systems analysis approach will be utilized to establish an IVIVC for each IV iron complex formulation.
- Gene Function and Pathway Analysis Using Systems Level Approaches in ProkaryotesCAROL ANNE GROSS; Fiscal Year: 2013..Thus, we function at the interface between systems analysis and mechanistic biology...
- Systems Approach to Immunity and InflammationRichard J Ulevitch; Fiscal Year: 2013..group will focus on mice identified by exome sequencing to have ENU induced mutations in genes predicted by systems analysis to be critical regulators of immune ceil networks and will establish the role of these genes in the immune ..
- Understanding Disparities in Obesity and its Comorbidities in the USYoufa Wang; Fiscal Year: 2010..Aim 3: To conduct simulation analyses using systems analysis approaches to examine the effects of potential interventions and scenarios for helping eliminate the ..
- Heart Failure Readmissions in Older Adults: A systems PerspectiveLEORA HORWITZ; Fiscal Year: 2013..group of large datasets;and (4) to develop advanced expertise in organizational behavior, human ergonomics, systems analysis and other techniques necessary for building safe and patient-centered healthcare systems...
- An Advanced Technology Flat-Panel Imager for FluoroscopyLarry E Antonuk; Fiscal Year: 2012..2) Quantitative modeling (involving cascaded systems analysis and detailed circuit simulations) to provide guidance in array design and assist in prototype evaluation...
- A systems approach to metabolic dysregulation in the heartMohit Jain; Fiscal Year: 2013..aims to leverage his prior training in cardiovascular physiology and disease with newly acquired skills in systems analysis, genomics, metabolomics and macro-molecule mass spectrometry within a structured and mentored scientific ..
- Cadiorenal and Metabolic Diseases Research CenterJohn E Hall; Fiscal Year: 2013..disease research at UMMC by recruiting new faculty with expertise in clinical and translational research and in emerging technologies, such as in vivo imaging, molecular genetics, bioinformatics, and systems analysis.
- Physiological Genomics of Critical Illness and InjuryJ Perren Cobb; Fiscal Year: 2009..the goal of which is to bring together those with the diverse skills sets necessary to apply genomics and systems analysis to the study of critical illness and injury...
- Complex Systems & Control of MMR-Deficient CellsKenneth Loparo; Fiscal Year: 2009..Through an iterative process that involves model development and systems analysis, experimentation and data collection, model testing and validation, and a detailed study of coordination and ..
- 2010 Neurobiology of Cognition Gordon Research ConferenceXiao Jing Wang; Fiscal Year: 2010..Neuroscience that have begun to uncover the brain circuit basis of higher cognitive functions at the level of systems analysis, computational principles, and neurophysiological mechanisms...
- Quantitative tools for investigating sensory systemsFrederic E Theunissen; Fiscal Year: 2010..The algorithms represent modern improvements to the classical engineering systems analysis approach that could only be applied to the most peripheral stages of sensory processing...
- Towards Effective and Efficient Adoption of Health IT in Home Health CareGünes Koru; Fiscal Year: 2013..far, the pressing challenges and opportunities of HHAs have not been sufficiently studied from an information systems analysis perspective...
- Systems analysis of cell type differentiation in xenopus developmentMARC WALLACE KIRSCHNER; Fiscal Year: 2013..Such studies could facilitate the development of procedures to direct cell differentiation in ways that would ultimately contribute to regenerative medicine in the treatment of important human diseases. ..
- TRAINING IN THE NEUROPLASTICITY OF AGINGEdward H Koo; Fiscal Year: 2013..technical expertise in the fields of Molecular Genetics, Protein Chemistry, Cell Biology, Neurophysiology, Systems Analysis, Pharmacology, Cognitive Neuroscience, Computational Neuroscience, and Clinical Neurology...
- Systems Analysis of BMP Regulation in Developing Zebrafish EmbryosDAVID MICHAEL UMULIS; Fiscal Year: 2013..Understanding the mechanism of BMP-mediated patterning in vertebrates will provide the basis for tightly controlling BMP signaling in tissue regeneration and other prospective treatments of human disease. ..
- Imaging in 2020-VIII: Integrating Molecular Imaging and Complex BiologyThomas J Meade; Fiscal Year: 2012..systems, animal and theoretical models to assess biological systems and the use of imaging in computational systems analysis. This year will expand the diversity of the scientists that gather in Jackson Hole to include systems ..
- HIPPOCAMPAL AND CORTICAL CODING IN MEMORYHoward B Eichenbaum; Fiscal Year: 2013..To understand the information processing mechanisms that underlie episodic memory, we propose a systems analysis that will compare the nature of information processing and identify functional interactions between cortical ..
- Development of Bimanual Coordination of Early ChildhoodKAREN E BRAKKE; Fiscal Year: 2010..Individual developmental trajectories will be mapped according to the principles and methods of developmental systems analysis. Additionally, introduction of auditory or human models will allow the investigator to determine whether ..
- Identifying network pertubation using secreted protein profiles in glioblastomaNathan D Price; Fiscal Year: 2011..but chose to defer this position for 2-3 years for the express purpose of transitioning his career focus onto systems analysis of cancer. The mentored phase of this award will provide Dr...
- Causes and Interventions for Childhood Obesity:Innovative Systems AnalysisYoufa Wang; Fiscal Year: 2013DESCRIPTION (provided by applicant): Causes and Interventions for Childhood Obesity: Innovative Systems Analysis Obesity has become a public health crisis in the United States...
- Johns Hopkins Pediatric Obesity Research and Training CenterYoufa Wang; Fiscal Year: 2012..The Center will build upon a solid research and training base with ongoing NIH funded projects directly related to childhood obesity and systems analysis.
- Mouse Genetic Resources for Multigeneic Disease AnalysisNathan A Berger; Fiscal Year: 2012..CSSs are a statistically powerful way to dissect the genetic control of these traits, simultaneously enabling gene discovery, functional studies, and systems analysis.
- Mouse Genetic Resources for Multigeneic Disease AnalysisNathan A Berger; Fiscal Year: 2011..CSSs are a statistically powerful way to dissect the genetic control of these traits, simultaneously enabling gene discovery, functional studies, and systems analysis.
- Computational investigation of neuropathic changes in primary afferent excitabiliSteven A Prescott; Fiscal Year: 2012..modeling will be used to replicate cellular excitability changes in minimal computer models so that dynamical systems analysis can be used to explain excitability changes on the basis of altered nonlinear interactions...
- Systems Analysis of Inflammatory Pathways in HIV InfectionDANA H GABUZDA; Fiscal Year: 2013..abstract_text> ..
- Systems Analysis and Improvement to Optimize pMTCT: A Cluster Randomized TrialKenneth Sherr; Fiscal Year: 2013DESCRIPTION (provided by applicant): Systems Analysis and Improvement to Optimize pMTCT: A Cluster Randomized Trial...
- Chemistry and Mechanisms for Environmental StressDaniel C Liebler; Fiscal Year: 2013..Toxicology" and highlights the implementation of global profiling technologies and data integration tools for systems analysis. The second is entitled "Chemistry and Biology of Metal Toxicity" and focuses on new mechanistic studies of ..
- Infrared microscopy for a systems approach to prostate pathologyRohit Bhargava; Fiscal Year: 2013..Predictions will be compared to the clinical standard today (Kattan nomogram). A systems analysis approach is proposed to examine important histologic and chemical transformations that characterize ..
- Modeling the Role of Differentiation in Cancer ProgressionSYLVIA KATINA PLEVRITIS; Fiscal Year: 2013..The Stanford CCSB will develop three essential and interlocking methods for a comprehensive systems analysis of cancer...
- NRSA Training Grant in Quantitative NeuroscienceKenneth A Norman; Fiscal Year: 2013..neuroscience, ranging from information-theoretic analyses of neuronal spiking and nonlinear dynamical systems analysis of decision- making to multivariate decoding of human neuroimaging data...
- A Systems Approach for Community-Linked Health Research Across the "Plaza"MAGDA G PECK; Fiscal Year: 2010..and reach greater shared understanding of community health issues amenable to collaborative research;data systems analysis, inventory, assessment and redesign to inform research priorities and support future research;development and ..
- SYSTEMS ANALYSIS OF HEAD STABILIZATIONBarry Peterson; Fiscal Year: 1999....
- IN VIVO DETECTION OF FREE RADICALS USING NMRThomas Clanton; Fiscal Year: 2000..abstract_text> ..
- PERCEPTUAL ORGANIZATION OF TWO DIMENSIONAL PATTERNSWilson S Geisler; Fiscal Year: 2013..In our lab we call this "natural systems analysis." This novel approach to vision science is composed of several steps: (1) identify natural tasks, (2) measure ..
- Neuromarkers of Social Coordination: A Dynamical ApproachJ A Scott Kelso; Fiscal Year: 2012..The research represents a first attempt to incorporate dynamical systems analysis into the study of socially-mediated neurophysiological activity in conscious, interacting humans...
- BIOMEDICAL COMPUTING SUPPORT FOR THE DIVISION OF CANCER CONTROL AND POPULATION SDAVID RONEY; Fiscal Year: 2013..The support provided are in the areas of (1) computer systems analysis, (2) programming, (3) data management, (4) data analysis, (5) statistical reporting, (6) WWW development and (..
- BIOMEDICAL COMPUTING SUPPORT FOR THE DIVISION OF CANCER CONTROL AND POPULATION SDAVID RONEY; Fiscal Year: 2012..The support provided are in the areas of (1) computer systems analysis, (2) programming, (3) data management, (4) data analysis, (5) statistical reporting, (6) WWW development and (..
- BIOMEDICAL COMPUTING SUPPORT FOR THE DIVISION OF CANCER CONTROL AND POPULATION SDAVID RONEY; Fiscal Year: 2010..The support provided are in the areas of (1) computer systems analysis, (2) programming, (3) data management, (4) data analysis, (5) statistical reporting, (6) WWW development and (..
- BIOMEDICAL COMPUTING SUPPORT FOR THE DIVISION OF CANCER CONTROL AND POPULATION SDAVID RONEY; Fiscal Year: 2011
- PROCESSES OF VISUAL TRACKINGMartin Gizzi; Fiscal Year: 1993..Phase I training includes instruction in neuro-ophthalmology, control systems analysis, electro-oculography and infrared oculography in humans, the use of magnetic search coils an physiological ..
- BLOOD PRESSURE & RENAL FUNCTION IN HYPERINSULINEMIAJohn Hall; Fiscal Year: 1991..A systems analysis of the interrelationships between insulin, body fluid homeostasis, and arterial pressure regulation will be ..
- Interrogation of systems level mechanisms controlling DNA repair processesNitin S Baliga; Fiscal Year: 2010..This hypothesis is motivated by two main observations: a. in systems analysis of UV response, although extraordinarily resistant, not all expected repair genes in this microbe responded ..
- IMPACT OF CAPITATION ON MH SERVICES TO THE CMIARIE SCHINNAR; Fiscal Year: 1992..Although the study is structured in a quasi-experimental framework it is intended as a systems analysis of the impact of a capitation financing experiment on Medicaid mental health clients: especially the CMI and ..
- NIDDK BIOTECHNOLOGY CENTER AT THE UNIVERSITY OF FLORIDAJin Xiong She; Fiscal Year: 2002..to researchers, the paradigm of analyzing a single gene effect in a biological system has shifted to a global systems analysis. New high-throughput technologies have created unparalleled opportunities to study the mechanism of diseases, ..
- Surveillance, Analysis, and Interventions to Improve Pa*Victoria Fraser; Fiscal Year: 2003..using critical incident analysis, root cause analysis, epidemiologic methods, and organizational and systems analysis to determine factors associated with errors...
- Systems analysis of oxygen regulation in HalobacteriumAMY SCHMID; Fiscal Year: 2007..These proposed experiments are expected to result in a transcriptional network model that addresses how organisms maintain homeostasis despite stress. [unreadable] [unreadable] [unreadable]..
- COMPUTER ANALYSIS OF AGING IN DICTYOSTELIUMBarbara Wright; Fiscal Year: 1992..understanding of the biochemical mechanisms responsible for differentiation and aging must be sought using a SYSTEMS analysis, at a level of complexity and integration much greater than that encompassed by any theory thus far ..
- Low-cost digital x-ray detectors using liquid crystalsJohn Rowlands; Fiscal Year: 2007..This visible image is then readout optically by a digital camera. The Methods to be used are linear systems analysis, Monte Carlo simulation, detective quantum efficiency (DQE) measurement, phantom tests, as well as comparison ..
- SYSTEMS ANALYSIS OF BARORECEPTOR REFLEXArtin Shoukas; Fiscal Year: 1992..As in Part A, the two mechanisms are removed sequentially and their separate and interactive contributions quantified. Plasma level of AVP and renin activity are measured and correlated with arterial pressure change...
- Acquisition of a 600-MHz Nuclear Magnetic Resonance SpectrometerJAMES GLOER; Fiscal Year: 2009..Projects dedicated to improving our molecular level understanding of muscular dystrophy, Parkinson's disease, and asthma, as well as the toxicology of environmental pollutants will also benefit from access to this instrument. ..